Detailed information for compound 1654135

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 358.299 | Formula: C18H14O8
  • H donors: 4 H acceptors: 6 LogP: 1.55 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)Cc1cc(O)cc2c1c(=O)cc(o2)c1cc(O)c(c(c1)O)O
  • InChi: 1S/C18H14O8/c1-25-16(23)5-9-2-10(19)6-15-17(9)11(20)7-14(26-15)8-3-12(21)18(24)13(22)4-8/h2-4,6-7,19,21-22,24H,5H2,1H3
  • InChiKey: KSXNMXZRSOPOBO-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0366 0.053
Echinococcus granulosus importin 5 0.0005 0.0006 0.0007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0241 0.0418
Onchocerca volvulus 0.0015 0.0231 0.0041
Loa Loa (eye worm) hypothetical protein 0.0035 0.0703 0.1018
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0621 0.1075
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2266 0.2459
Schistosoma mansoni hypothetical protein 0.0015 0.0241 0.0262
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0539 0.0815
Trypanosoma brucei glucose transporter 1E 0.0032 0.0621 0.5932
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0414 0.0449
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0539 0.5153
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0231 0.0251
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0084 0.0122
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0231 0.0251
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.2605 0.3773
Echinococcus granulosus snurportin 1 0.0301 0.6904 0.7494
Echinococcus multilocularis Smad4 0.0008 0.0067 0.0073
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0773 0.0767
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0006 0.0016 0.0127
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0715 0.6834
Echinococcus multilocularis geminin 0.0166 0.3747 0.4068
Plasmodium falciparum hexose transporter 0.0102 0.2266 0.2261
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.0035 0.0703 0.1018
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0231 0.0251
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0217 0.0376
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.3747 0.6491
Echinococcus granulosus cpg binding protein 0.003 0.0574 0.0623
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0703 0.137
Loa Loa (eye worm) solute carrier family 6 member 4 0.0015 0.0231 0.0335
Toxoplasma gondii sugar transporter ST2 0.0014 0.0217 0.0327
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.3747 0.6491
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.0401
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0099 0.2192 0.2379
Treponema pallidum sodium- and chloride- dependent transporter 0.0015 0.0231 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.1019 0.1476
Leishmania major hypothetical protein, conserved 0.0005 0.0006 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Trichomonas vaginalis esterase, putative 0.0035 0.0703 0.1217
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.2266 0.3924
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0231 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.003 0.0052
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0175 0.0254
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0703 0.6715
Echinococcus granulosus GPCR family 2 0.0015 0.0241 0.0262
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0414 0.5256
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0414 0.0449
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0597 0.0648
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0162 0.3671 0.7156
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0231 0.0251
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0612 0.0664
Brugia malayi MH2 domain containing protein 0.0117 0.2605 0.4513
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2266 0.2459
Brugia malayi Sugar transporter family protein 0.0102 0.2266 0.3925
Echinococcus multilocularis snurportin 1 0.0301 0.6904 0.7494
Echinococcus multilocularis dnaJ subfamily B 0.04 0.9212 1
Echinococcus multilocularis General substrate transporter 0.0088 0.193 0.2096
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0375
Schistosoma mansoni glycyl-tRNA synthetase 0.0006 0.0016 0.0017
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0217 0.0235
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0067 0.0073
Brugia malayi Cam kinase protein 1 0.0031 0.0612 0.106
Brugia malayi MH2 domain containing protein 0.0008 0.0067 0.0116
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.1204 0.1819
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0566 0.0615
Loa Loa (eye worm) hypothetical protein 0.0033 0.0659 0.0955
Leishmania major hypothetical protein, conserved 0.0014 0.0217 0.2071
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0067 0.0097
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0006 0.0016 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0612 0.1059
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.2192 0.2379
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0612 0.0664
Loa Loa (eye worm) hypothetical protein 0.0035 0.0703 0.1018
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0082 0.0142
Brugia malayi hypothetical protein 0.0014 0.0217 0.0376
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0659 0.1142
Brugia malayi MH1 domain containing protein 0.0008 0.0067 0.0116
Brugia malayi Sugar transporter family protein 0.0014 0.0217 0.0376
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0044 0.0048
Trypanosoma cruzi hexose transporter 0.0032 0.0621 0.5932
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0715 0.071
Echinococcus granulosus solute carrier family 22 0.0014 0.0217 0.0235
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0366 0.3493
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.0335
Plasmodium falciparum threonine--tRNA ligase 0.0006 0.0016 0.001
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0231 0.0226
Plasmodium falciparum amino acid transporter, putative 0.0015 0.0231 0.0226
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0597 0.849
Plasmodium vivax importin-beta 2, putative 0.0028 0.0539 0.0534
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0703 0.137
Loa Loa (eye worm) hypothetical protein 0.0015 0.0231 0.0335
Loa Loa (eye worm) hypothetical protein 0.0099 0.2192 0.3175
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0414 1
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0621 0.1075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0463 0.067
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0612 0.0606
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0006 0.0016 0.0027
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0612 0.0925
Brugia malayi MH1 domain containing protein 0.0008 0.0067 0.0116
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0415 0.0719
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0715 0.6834
Echinococcus multilocularis smad 0.0008 0.0067 0.0073
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0597 0.7675
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.1047 0.1041
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5773 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.5932
Toxoplasma gondii HEAT repeat-containing protein 0.0005 0.0006 0.0009
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0334 0.4744
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0612 0.0664
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0142 0.3188 0.3461
Brugia malayi CXXC zinc finger family protein 0.0028 0.0537 0.093
Loa Loa (eye worm) hypothetical protein 0.0015 0.0231 0.0335
Echinococcus granulosus importin subunit beta 1 0.0028 0.0539 0.0586
Mycobacterium ulcerans lipase LipD 0.0035 0.0703 0.1915
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.2192 0.2379
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0067 0.0073
Mycobacterium ulcerans beta-lactamase 0.0035 0.0703 0.1915
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0217 0.0375
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.0401
Loa Loa (eye worm) beta-lactamase 0.0035 0.0703 0.1018
Plasmodium falciparum transporter, putative 0.0015 0.0231 0.0226
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0165 0.3734 0.5643
Schistosoma mansoni glucose transport protein 0.0102 0.2266 0.2459
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.5932
Schistosoma mansoni cpg binding protein 0.003 0.0574 0.0623
Schistosoma mansoni sugar transporter 0.0014 0.0217 0.0235
Brugia malayi Smad1 0.0008 0.0067 0.0116
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0414 0.3952
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0621 0.5932
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0415 0.3964
Echinococcus granulosus Smad4 0.0008 0.0067 0.0073
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0006 0.0016 0.0043
Schistosoma mansoni glucose transport protein 0.0102 0.2266 0.2459
Entamoeba histolytica hypothetical protein 0.0023 0.0415 0.5333
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.1047 0.1582
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0612 0.106
Entamoeba histolytica hypothetical protein 0.0023 0.0414 0.5317
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.035
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0621 0.5932
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.5932
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.3747 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0231 0.0335
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.2266 0.2459
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0015 0.0231 0.5419
Brugia malayi acetyltransferase, GNAT family protein 0.0142 0.3188 0.5522
Leishmania major hypothetical protein, conserved 0.005 0.1047 1
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0006 0.0016 0.0023
Toxoplasma gondii hypothetical protein 0.0015 0.0231 0.035
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Schistosoma mansoni protein kinase 0.0031 0.0612 0.0664
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5773 1
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0414 0.0408
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0703 0.0763
Plasmodium falciparum mitogen-activated protein kinase 2 0.0165 0.3734 0.373
Brugia malayi hypothetical protein 0.0014 0.0217 0.0376
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0703 0.6715
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0366 0.036
Loa Loa (eye worm) Smad1 0.0008 0.0067 0.0097
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0703 0.0763
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0231 0.0251
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.0401
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0854 0.0927
Schistosoma mansoni ran 0.0021 0.0366 0.0397
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0006 0.0016 0.0017
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0597 0.1034
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0044 0.0048
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.3955 0.6851
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0703 0.137
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0612 0.0664
Mycobacterium ulcerans sugar transporter 0.0014 0.0217 0.059
Leishmania major hypothetical protein, conserved 0.0035 0.0703 0.6715
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Brugia malayi hypothetical protein 0.0014 0.0217 0.0376
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0703 0.1217
Loa Loa (eye worm) kap beta 3 protein 0.0005 0.0006 0.0009
Schistosoma mansoni hypothetical protein 0.0166 0.3747 0.4068
Loa Loa (eye worm) importin-beta domain-containing protein 0.0005 0.0006 0.0009
Schistosoma mansoni smad 0.0008 0.0067 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0703 0.6715
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0231 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.003 0.0052
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0621 0.5932
Echinococcus granulosus General substrate transporter 0.0088 0.193 0.2096
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.3747 0.6491
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0414 0.1127
Schistosoma mansoni hypothetical protein 0.04 0.9212 1
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0006 0.0016 0.0023
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0044 0.0048
Loa Loa (eye worm) acetyltransferase 0.0142 0.3188 0.4618
Toxoplasma gondii sugar transporter ST3 0.0014 0.0217 0.0327
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0612 0.0664
Plasmodium vivax sugar transporter, putative 0.0014 0.0217 0.0211
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0539 0.5153
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.5932
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0414 0.0717
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0134 0.0365
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0149
Schistosoma mansoni smad1 5 8 and 0.0008 0.0067 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0015 0.0231 0.0335
Loa Loa (eye worm) hypothetical protein 0.0015 0.0231 0.0335
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0005 0.0006 0.0056
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.1019 0.1765
Toxoplasma gondii ABC1 family protein 0.0035 0.0703 0.1062
Schistosoma mansoni smad1 5 8 and 0.0008 0.0067 0.0073
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0703 0.1218
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.3747 0.6491
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0854 0.129
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0612 0.0664
Trichomonas vaginalis ran, putative 0.0021 0.0366 0.0633
Schistosoma mansoni hypothetical protein 0.0166 0.3747 0.4068
Echinococcus multilocularis importin 5 0.0005 0.0006 0.0007
Brugia malayi Importin beta-1 subunit 0.0028 0.0539 0.0934
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0217 0.0376
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.1047 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0231 0.0335
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0241 0.0262
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0217 0.2071
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0241 0.035
Loa Loa (eye worm) hypothetical protein 0.0035 0.0703 0.1018
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0597 0.7704
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Schistosoma mansoni ran 0.0021 0.0366 0.0397
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.2266 0.3424
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2266 0.2459
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0366 0.3493
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0597 0.0648
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0006 0.0016 0.003
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0044 0.0048
Brugia malayi Sugar transporter family protein 0.0014 0.0217 0.0376
Mycobacterium ulcerans hypothetical protein 0.0035 0.0703 0.1915
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0217 0.0235
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0703 0.0697
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.1019 0.1765
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0366 0.0552
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0217 0.059
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2266 0.2459
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Brugia malayi major facilitator superfamily protein 0.0014 0.0217 0.0376
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0612 0.0606
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.3747 0.6491
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0612 0.5843
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0537 0.0778
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0134 0.5495
Brugia malayi glycyl-tRNA synthetase 0.0006 0.0016 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0715 0.6834
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Echinococcus multilocularis translational activator gcn1 0.0005 0.0006 0.0007
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0414 0.0716
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0612 0.0606
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.5773 0.8362
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0231 0.0401
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0612 0.0925
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0301 0.6904 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0044 0.0048
Loa Loa (eye worm) hypothetical protein 0.0015 0.0241 0.035
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Leishmania major protein kinase, putative 0.0031 0.0612 0.5843
Schistosoma mansoni hypothetical protein 0.0033 0.0659 0.0715
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0231 0.0251
Loa Loa (eye worm) norepinephrine transporter 0.0015 0.0231 0.0335
Echinococcus multilocularis solute carrier family 22 0.0014 0.0217 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Onchocerca volvulus 0.0015 0.0231 0.0041
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2266 0.2459
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0217 0.0314
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.003 0.0052
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0217 0.0314
Schistosoma mansoni cpg binding protein 0.0028 0.0537 0.0583
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.1047 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0854 0.129
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0286 0.2729
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.0401
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0621 0.1075
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.3747 0.6491
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0366 0.0634
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.5129 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0703 0.1217
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0703 0.1018
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0006 0.0016 0.0027
Brugia malayi hypothetical protein 0.0015 0.0231 0.0401
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.5932
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0404 0.0439
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0715 0.6834
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Leishmania major importin beta-1 subunit, putative 0.0023 0.0415 0.3964
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Mycobacterium leprae Probable lipase LipE 0.0035 0.0703 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.0016 0.0023
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0715 0.1081
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.1047 0.1041
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0231 0.0251
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0597 0.0648
Entamoeba histolytica Ran family GTPase 0.0021 0.0366 0.469
Leishmania major glucose transporter, lmgt2 0.0032 0.0621 0.5932
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Loa Loa (eye worm) hypothetical protein 0.0015 0.0231 0.0335
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0854 0.1479
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0027
Loa Loa (eye worm) sugar transporter 0.0014 0.0217 0.0314
Loa Loa (eye worm) hypothetical protein 0.0028 0.0539 0.0781
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0217 0.0235
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5773 1
Plasmodium vivax glycine--tRNA ligase, putative 0.0006 0.0016 0.001
Loa Loa (eye worm) serotonin transporter b 0.0015 0.0231 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0621 0.1075
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0217 0.0235
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0414 0.3952
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0084 0.0092
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0414 0.0449
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0612 0.0606
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0165 0.3734 0.373
Schistosoma mansoni hypothetical protein 0.0015 0.0241 0.0262
Echinococcus granulosus Threonyl tRNA synthetase C 0.0006 0.0016 0.0017
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0014 0.0217 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0231 0.0251
Onchocerca volvulus 0.0015 0.0231 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0375
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.3955 0.6851
Toxoplasma gondii protein kinase, putative 0.0289 0.6617 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0142 0.3188 0.3461
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0241 0.0262
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0099 0.2192 0.2379
Entamoeba histolytica protein kinase, putative 0.0031 0.0612 0.7897
Plasmodium vivax amine transporter, putative 0.0015 0.0231 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.5773 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.2192 0.3175
Onchocerca volvulus 0.0015 0.0231 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Brugia malayi beta-lactamase family protein 0.0035 0.0703 0.1218
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0006 0.0016 0.0043
Leishmania major GTP-binding protein, putative 0.0021 0.0366 0.3493
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0703 0.1915
Loa Loa (eye worm) hypothetical protein 0.0031 0.0597 0.0865
Onchocerca volvulus 0.0035 0.0703 0.1377
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5773 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.003 0.0052
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0773 1
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0006 0.0016 0.0149
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2266 0.2459
Echinococcus multilocularis solute carrier family 22 0.0014 0.0217 0.0235
Onchocerca volvulus 0.0028 0.0537 0.0906
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0703 0.1217
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0703 0.137
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0067 0.0073
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0773 1
Trichomonas vaginalis hypothetical protein 0.0005 0.0006 0.001
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Giardia lamblia Hexose transporter 0.0014 0.0217 0.2656
Echinococcus multilocularis serotonin transporter 0.0015 0.0231 0.0251
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0127
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Giardia lamblia Sugar-proton symporter 0.0014 0.0217 0.2656
Onchocerca volvulus 0.0035 0.0703 0.1377
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0703 0.0763
Brugia malayi beta-lactamase 0.0035 0.0703 0.1218
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0715 0.6834
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0241 0.0262
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0217 0.0375
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.2605 0.3773
Brugia malayi MH2 domain containing protein 0.0008 0.0067 0.0116
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Echinococcus granulosus solute carrier family 22 0.0014 0.0217 0.0235
Echinococcus multilocularis glycyl tRNA synthetase 0.0006 0.0016 0.0017
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0084 0.0092
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0715 0.071
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0334 0.065
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0703 1
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0703 0.137
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0612 0.0664
Brugia malayi major facilitator superfamily protein 0.0014 0.0217 0.0376
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Schistosoma mansoni protein kinase 0.0031 0.0612 0.0664
Loa Loa (eye worm) hypothetical protein 0.005 0.1047 0.1516
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0067 0.0097
Echinococcus multilocularis cpg binding protein 0.003 0.0574 0.0623
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0006 0.0016 0.0222
Leishmania major threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0149
Echinococcus granulosus glycyl tRNA synthetase 0.0006 0.0016 0.0017
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0597 0.0648
Loa Loa (eye worm) hypothetical protein 0.0035 0.0703 0.1018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.003 0.0052
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0217 0.0327
Loa Loa (eye worm) hypothetical protein 0.0014 0.0217 0.0314
Toxoplasma gondii HEAT repeat-containing protein 0.0005 0.0006 0.0009
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0414 0.5885
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0597 0.0865
Loa Loa (eye worm) sugar transporter 0.0102 0.2266 0.3282
Loa Loa (eye worm) hypothetical protein 0.0015 0.0231 0.0335
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0366 0.3493
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0414 0.1127
Trichomonas vaginalis helicase, putative 0.0006 0.003 0.0052
Chlamydia trachomatis proline--tRNA ligase 0.0011 0.0134 0.2978
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0612 0.0606
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0414 0.0408
Echinococcus granulosus smad 0.0008 0.0067 0.0073
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0366 0.036
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0334 0.065
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0612 0.0886
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0217 0.0211
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0703 0.1915
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0539 0.0586
Loa Loa (eye worm) hypothetical protein 0.0023 0.0414 0.0599
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0612 0.0606
Onchocerca volvulus 0.0035 0.0703 0.1377
Brugia malayi beta-lactamase family protein 0.0035 0.0703 0.1218
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0217 0.2071
Toxoplasma gondii glycyl-tRNA synthetase 0.0006 0.0016 0.0024
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.3095 0.336
Schistosoma mansoni glucose transport protein 0.0102 0.2266 0.2459
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0231 0.0251
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0703 0.1217
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0621 0.1075
Echinococcus granulosus dnaJ subfamily B 0.04 0.9212 1
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0597 0.1034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.003 0.0052
Plasmodium vivax hexose transporter 0.0102 0.2266 0.2261
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0415 0.0719
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0703 0.137
Schistosoma mansoni Smad4 0.0008 0.0067 0.0073
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0621 0.5932
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Brugia malayi RNA, U transporter 1 0.008 0.1752 0.3035
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0414 0.0625
Schistosoma mansoni glucose transporter 0.0014 0.0217 0.0235
Schistosoma mansoni hypothetical protein 0.0022 0.0404 0.0439
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.1047 0.1041
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0149
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0231 0.0251
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0231 0.0251
Schistosoma mansoni hypothetical protein 0.0102 0.2266 0.2459
Mycobacterium ulcerans epoxide hydrolase EphA 0.0162 0.3671 1
Echinococcus granulosus translational activator gcn1 0.0005 0.0006 0.0007
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0703 0.0763
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0217 0.0376
Schistosoma mansoni smad1 5 8 and 0.0008 0.0067 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0231 0.0251
Echinococcus granulosus geminin 0.0166 0.3747 0.4068
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0415 0.0719
Toxoplasma gondii sugar transporter ST1 0.0014 0.0217 0.0327
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0621 0.1075
Trypanosoma brucei sugar transporter, putative 0.0014 0.0217 0.2071
Trypanosoma brucei glucose transporter 2A 0.0032 0.0621 0.5932
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0612 0.0925
Schistosoma mansoni hypothetical protein 0.0015 0.0241 0.0262
Schistosoma mansoni importin-beta 2 0.0005 0.0006 0.0007
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0241 0.0418
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0007 0.0052 0.0492
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.0335
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0217 0.059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.003 0.0052
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0348 0.0603
Loa Loa (eye worm) hypothetical protein 0.0035 0.0703 0.1018
Echinococcus multilocularis solute carrier family 22 0.0014 0.0217 0.0235
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0612 0.0606
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0277 0.0301
Brugia malayi hypothetical protein 0.0032 0.0634 0.1098
Plasmodium falciparum protein kinase 7 0.0289 0.6617 0.6615
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0854 0.0848
Schistosoma mansoni hypothetical protein 0.0301 0.6904 0.7494
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0366 0.0397
Leishmania major glucose transporter, lmgt3 0.0032 0.0621 0.5932
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.1047 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0241 0.0262
Schistosoma mansoni hypothetical protein 0.0015 0.0241 0.0262
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0217 0.2071
Schistosoma mansoni sugar transporter 0.0014 0.0217 0.0235
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0067 0.0073
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0006 0.0016 0.0149
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0703 0.137
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0217 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0231 0.0251
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0217 0.2071
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.1271 0.138
Echinococcus granulosus transportin 1 0.0005 0.0006 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.003 0.0052
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0366 0.0397
Plasmodium vivax threonine--tRNA ligase, putative 0.0006 0.0016 0.001
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0621 0.5932
Loa Loa (eye worm) hypothetical protein 0.0049 0.1019 0.1476
Echinococcus multilocularis transportin 1 0.0005 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0612 0.0886
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0854 0.1479
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Schistosoma mansoni sugar transporter 0.0014 0.0217 0.0235
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0231 0.0251
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0597 0.1034
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0414 0.0449
Leishmania major glucose transporter, lmgt1 0.0032 0.0621 0.5932
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.5932
Mycobacterium tuberculosis Conserved protein 0.0035 0.0703 0.137
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0217 0.059
Echinococcus granulosus solute carrier family 22 0.0014 0.0217 0.0235
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0612 0.0606
Toxoplasma gondii hypothetical protein 0.0015 0.0231 0.035
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0612 0.0664
Mycobacterium tuberculosis Conserved protein 0.0035 0.0703 0.137
Entamoeba histolytica protein kinase, putative 0.0031 0.0612 0.7897
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0217 0.0235
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0621 0.5932
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2266 0.2459
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.5932
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0217 0.0423
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0612 0.0886
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0099 0.2192 0.2379
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.3747 0.6491
Brugia malayi kap beta 3 protein 0.0005 0.0006 0.001
Schistosoma mansoni protein kinase 0.0031 0.0612 0.0664
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Plasmodium vivax CDK-related protein kinase 6, putative 0.0434 1 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0621 0.5932
Echinococcus multilocularis solute carrier family 22 0.0014 0.0217 0.0235
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5773 1
Schistosoma mansoni cpg binding protein 0.003 0.0574 0.0623
Schistosoma mansoni sugar transporter 0.0014 0.0217 0.0235
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0366 0.4622
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0703 0.1217
Plasmodium falciparum importin beta, putative 0.0028 0.0539 0.0534
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0414 0.3952
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0217 0.2071
Schistosoma mansoni importin beta-1 0.0028 0.0539 0.0586
Echinococcus granulosus serotonin transporter 0.0015 0.0231 0.0251
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0231 0.0251
Mycobacterium tuberculosis Conserved protein 0.0035 0.0703 0.137
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0217 0.0375
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0217 0.0423
Echinococcus granulosus solute carrier family 22 0.0014 0.0217 0.0235
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0621 0.5932
Echinococcus multilocularis GPCR, family 2 0.0015 0.0241 0.0262
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0612 0.0606
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.035
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0612 0.0664
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0067 0.0073
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0566 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.003 0.0052
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0231 0.035
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.5773 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0621 0.1075
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0231 0.0251
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0404 0.0439
Brugia malayi hypothetical protein 0.005 0.1047 0.1813

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Antibacterial activity against Escherichia coli MTCC 739 at 80 ug/ml by modified microtiter broth dilution method ChEMBL. 22677320

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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