Detailed information for compound 173434

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 309.344 | Formula: C20H13N4+
  • H donors: 1 H acceptors: 1 LogP: 4.25 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nn1c2cc3c(n[n+]2c2c1cccc2)c1c2c3cccc2ccc1
  • InChi: 1S/C20H13N4/c21-23-16-9-1-2-10-17(16)24-18(23)11-15-13-7-3-5-12-6-4-8-14(19(12)13)20(15)22-24/h1-11H,21H2/q+1
  • InChiKey: UQGIQGYTNKMXQU-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0018 0.0023 0.0048
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0232 0.0467
Brugia malayi YY1-associated factor 2 0.0348 0.1613 0.3467
Brugia malayi MH2 domain containing protein 0.0025 0.0056 0.0113
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0023 0.0048
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0016
Echinococcus multilocularis geminin 0.0171 0.0758 0.0758
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0018 0.0018
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0018 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Mycobacterium tuberculosis Conserved protein 0.0037 0.0115 0.0943
Brugia malayi MH1 domain containing protein 0.0025 0.0056 0.0113
Onchocerca volvulus 0.0477 0.2231 0.4776
Schistosoma mansoni survival motor neuron protein 0.0048 0.0168 0.0235
Leishmania major hypothetical protein, unknown function 0.0018 0.0023 0.0048
Schistosoma mansoni hypothetical protein 0.0348 0.1613 0.2395
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0114 0.0155
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0248
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0979 0.4645 0.4645
Plasmodium falciparum zinc finger protein, putative 0.0018 0.0023 0.0016
Schistosoma mansoni cellular tumor antigen P53 0.0306 0.1411 0.2093
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.001 0.001
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0018 0.0023 0.0016
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.2177 0.2177
Loa Loa (eye worm) hypothetical protein 0.0306 0.1411 0.3037
Leishmania major hypothetical protein, conserved 0.0026 0.0062 0.0286
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0115 0.0115
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0248
Onchocerca volvulus 0.0061 0.0233 0.0452
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.001 0.001
Onchocerca volvulus 0.0348 0.1613 0.3438
Toxoplasma gondii hypothetical protein 0.0018 0.0023 0.0016
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Loa Loa (eye worm) RING finger protein 20 0.0018 0.0023 0.0051
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Brugia malayi CXXC zinc finger family protein 0.0058 0.0215 0.0456
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0058 0.15
Brugia malayi hypothetical protein 0.0018 0.0023 0.0043
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0979 0.4645 1
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0348 0.1613 0.3438
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0115 0.0246
Entamoeba histolytica hypothetical protein 0.0037 0.0114 1
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0115 0.0621
Schistosoma mansoni ap endonuclease 0.0019 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0301 0.1388 0.2989
Loa Loa (eye worm) histone methyltransferase 0.002 0.0034 0.0074
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0248
Echinococcus granulosus Smad4 0.0025 0.0056 0.0056
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0115 0.0943
Echinococcus granulosus microtubule associated protein 2 0.1406 0.6702 0.6702
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0248
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0115 0.0621
Toxoplasma gondii RING zinc finger protein 0.0018 0.0023 0.0016
Echinococcus granulosus ring finger protein 113a 0.0018 0.0023 0.0023
Plasmodium falciparum RING zinc finger protein, putative 0.0018 0.0023 0.0016
Echinococcus granulosus lamin dm0 0.0027 0.0066 0.0066
Schistosoma mansoni smad1 5 8 and 0.0025 0.0056 0.0068
Leishmania major DNA repair protein-like protein 0.0018 0.0023 0.0048
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Schistosoma mansoni cpg binding protein 0.0058 0.0215 0.0306
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.001 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0089 0.0089
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0018 0.0023 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0232 1
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0066 0.0142
Brugia malayi hypothetical protein 0.0018 0.0023 0.0043
Leishmania major hypothetical protein, conserved 0.0348 0.1613 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0016
Brugia malayi beta-lactamase family protein 0.0037 0.0115 0.0241
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0027 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0023 0.0048
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0027 0.0057
Echinococcus multilocularis smad 0.0025 0.0056 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Onchocerca volvulus 0.0301 0.1388 0.2953
Toxoplasma gondii ABC1 family protein 0.0037 0.0115 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0348 0.1613 0.1613
Loa Loa (eye worm) hypothetical protein 0.0026 0.0064 0.0137
Onchocerca volvulus 0.0348 0.1613 0.3438
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0232 0.0331
Schistosoma mansoni cpg binding protein 0.0061 0.0231 0.0329
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0089 0.0191
Loa Loa (eye worm) RiNg Finger protein family member 0.0018 0.0023 0.0051
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Chlamydia trachomatis DNA topoisomerase I 0.0979 0.4645 0.5
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0056 0.0056
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0115 0.5
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0034 0.0034
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0018 0.0023 0.0023
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0044 0.0087
Echinococcus granulosus smad 0.0025 0.0056 0.0056
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Plasmodium falciparum trophozoite exported protein 1 0.0018 0.0023 0.0016
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0132
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0215 0.0463
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0056 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0018 0.0023 0.0023
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.2177 0.2177
Onchocerca volvulus 0.0348 0.1613 0.3438
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0168 0.0354
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0419 0.1954 0.4205
Onchocerca volvulus 0.0048 0.0168 0.0312
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trypanosoma brucei DNA repair protein, putative 0.0018 0.0023 0.0048
Toxoplasma gondii ran binding protein 0.0348 0.1613 0.3449
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0115 0.0156
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0115 0.4282
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0016 0.0027
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.001 0.001
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0089 0.0089
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0018 0.0023 0.0016
Echinococcus multilocularis musashi 0.0027 0.0066 0.0066
Onchocerca volvulus 0.0979 0.4645 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0044 0.0044
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0115 0.4282
Loa Loa (eye worm) hypothetical protein 0.0068 0.0264 0.0568
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.001 0.0015
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0348 0.1613 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0016 0.0034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0089 0.0191
Brugia malayi RING finger protein 20 0.0018 0.0023 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0348 0.1613 0.3472
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0115 0.0943
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0019
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0062 0.0099
Schistosoma mansoni TRABID protein (C64 family) 0.0348 0.1613 0.2395
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Loa Loa (eye worm) hypothetical protein 0.0348 0.1613 0.3472
Echinococcus granulosus Zinc finger RanBP2 type 0.0348 0.1613 0.1613
Toxoplasma gondii helicase, putative 0.0018 0.0023 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0115 0.0246
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0232 0.2056
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0018 0.0023 0.0048
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0348 0.1613 1
Schistosoma mansoni Smad4 0.0025 0.0056 0.0068
Leishmania major hypothetical protein, conserved 0.0348 0.1613 1
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0348 0.1613 0.3449
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0018 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0979 0.4645 1
Brugia malayi hypothetical protein 0.0018 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Schistosoma mansoni smad 0.0025 0.0056 0.0068
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0979 0.4645 1
Echinococcus multilocularis lamin 0.0027 0.0066 0.0066
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0076 0.0303 0.0646
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0018 0.0023 0.0023
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0066 0.0255 0.0549
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0062 0.0099
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0348 0.1613 1
Schistosoma mansoni hypothetical protein 0.0979 0.4645 0.6927
Echinococcus granulosus cpg binding protein 0.0061 0.0231 0.0231
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0018 0.0023 0.0016
Schistosoma mansoni brg-1 associated factor 0.0979 0.4645 0.6927
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0233 0.0332
Brugia malayi intermediate filament protein 0.0027 0.0066 0.0135
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0027 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0233 0.0233
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.002
Schistosoma mansoni peter pan-related 0.0018 0.0023 0.0019
Toxoplasma gondii hypothetical protein 0.0018 0.0023 0.0016
Brugia malayi isocitrate dehydrogenase 0.0016 0.0016 0.0027
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0018 0.0023 0.0048
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0044 0.0044
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0232 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Schistosoma mansoni hypothetical protein 0.0031 0.0089 0.0117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0233 0.0332
Loa Loa (eye worm) hypothetical protein 0.0234 0.1063 0.2288
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0058 0.0125
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0232 0.0331
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0115 0.0943
Onchocerca volvulus Huntingtin homolog 0.0122 0.0526 0.1087
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.036 0.1668 0.3591
Toxoplasma gondii hypothetical protein 0.0018 0.0023 0.0016
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0056 0.0056
Brugia malayi Cytochrome P450 family protein 0.0025 0.0058 0.0118
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0348 0.1613 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0018 0.0023 0.0048
Leishmania major hypothetical protein 0.0018 0.0023 0.0048
Schistosoma mansoni hypothetical protein 0.0171 0.0758 0.1118
Echinococcus multilocularis 0.0018 0.0023 0.0023
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0115 0.0248
Onchocerca volvulus 0.0027 0.0066 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0115 0.0214
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0115 0.0943
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0023 0.0048
Schistosoma mansoni zinc finger protein 0.0348 0.1613 0.2395
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0058 0.0265
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Echinococcus granulosus lamin 0.0027 0.0066 0.0066
Brugia malayi beta-lactamase 0.0037 0.0115 0.0241
Echinococcus granulosus ring and YY1 binding protein 0.0348 0.1613 0.1613
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0248
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.1063 0.1063
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0018 0.0023 0.0019
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0027 0.0027
Loa Loa (eye worm) brahma associated protein 0.0979 0.4645 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0816 0.3863 0.3863
Brugia malayi MH1 domain containing protein 0.0025 0.0056 0.0113
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0115 0.0241
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0095
Mycobacterium ulcerans hypothetical protein 0.0037 0.0115 0.4282
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0016
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0264 0.0561
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0023
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Brugia malayi MH2 domain containing protein 0.0025 0.0056 0.0113
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0076 0.0303 0.0653
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0062 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0348 0.1613 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0007 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0023 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0115 0.0621
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Echinococcus multilocularis dnaJ subfamily B 0.0819 0.3879 0.3879
Echinococcus granulosus geminin 0.0171 0.0758 0.0758
Brugia malayi hypothetical protein 0.0017 0.0018 0.0031
Schistosoma mansoni microtubule-associated protein tau 0.1406 0.6702 1
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0979 0.4645 0.4645
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0348 0.1613 0.1613
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0019
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0089 0.0089
Mycobacterium leprae Probable lipase LipE 0.0037 0.0115 0.5
Brugia malayi Pre-SET motif family protein 0.0061 0.0233 0.0493
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0089 0.0184
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0348 0.1613 0.3467
Schistosoma mansoni hypothetical protein 0.0031 0.0089 0.0117
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0018 0.0023 0.0016
Entamoeba histolytica hypothetical protein 0.0037 0.0114 1
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0018 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0348 0.1613 0.3472
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0051
Trichomonas vaginalis ankyrin, putative 0.0018 0.0023 0.0048
Echinococcus multilocularis ring finger protein 170 0.0018 0.0023 0.0023
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0027 0.0025
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0018 0.0023 0.0016
Echinococcus granulosus zinc finger protein Ran binding 0.0348 0.1613 0.1613
Brugia malayi RING zinc finger protein 0.0018 0.0023 0.0043
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.001 0.001
Brugia malayi Zinc finger protein 183 homolog 0.0018 0.0023 0.0043
Brugia malayi SWIB/MDM2 domain containing protein 0.0979 0.4645 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0018 0.0023 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0115 0.0246
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Onchocerca volvulus 0.0037 0.0115 0.0198
Echinococcus multilocularis Smad4 0.0025 0.0056 0.0056
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.1063 0.1063
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0115 0.0246
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0115 0.0943
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0066 0.0135
Echinococcus granulosus dnaJ subfamily B 0.0819 0.3879 0.3879
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0115 0.0115
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0279 0.0599
Mycobacterium tuberculosis Conserved protein 0.0037 0.0115 0.0943
Schistosoma mansoni ring finger protein 151 0.0018 0.0023 0.0019
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Brugia malayi Pre-SET motif family protein 0.0419 0.1954 0.4201
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0232 0.0232
Trypanosoma cruzi hypothetical protein 0.0018 0.0023 0.0048
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0066 0.0142
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0062 0.0286
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0348 0.1613 1
Onchocerca volvulus Huntingtin homolog 0.0122 0.0526 0.1087
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0023 0.0048
Schistosoma mansoni peter pan-related 0.0018 0.0023 0.0019
Brugia malayi hypothetical protein 0.0122 0.0526 0.1125
Schistosoma mansoni cpg binding protein 0.0061 0.0231 0.0329
Echinococcus granulosus ring finger protein 170 0.0018 0.0023 0.0023
Brugia malayi MH2 domain containing protein 0.036 0.1668 0.3587
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0062 0.0286
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Plasmodium vivax SET domain protein, putative 0.0061 0.0233 0.0468
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0058 0.0125
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0232 1
Brugia malayi brahma associated protein 60 kDa 0.0979 0.4645 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0027 0.5
Schistosoma mansoni hypothetical protein 0.0979 0.4645 0.6927
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0018 0.0018
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0037 0.0114 0.0155
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Onchocerca volvulus 0.0037 0.0115 0.0198
Trichomonas vaginalis esterase, putative 0.0037 0.0115 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Echinococcus multilocularis cpg binding protein 0.0061 0.0231 0.0231
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Toxoplasma gondii hypothetical protein 0.0018 0.0023 0.0016
Echinococcus multilocularis SWI:SNF matrix associated 0.0979 0.4645 0.4645
Plasmodium vivax RING zinc finger protein, putative 0.0018 0.0023 0.0016
Trypanosoma cruzi WLM domain containing protein, putative 0.0348 0.1613 1
Trypanosoma brucei hypothetical protein, conserved 0.0348 0.1613 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0216 0.0216
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0115 0.0943
Trichomonas vaginalis conserved hypothetical protein 0.0979 0.4645 1
Echinococcus granulosus SWI:SNF matrix associated 0.0979 0.4645 0.4645
Schistosoma mansoni hypothetical protein 0.0048 0.0168 0.0235
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0023 0.0048
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0018 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0536 0.0785
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.2177 0.2177
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Trichomonas vaginalis ion channel nompc, putative 0.0018 0.0023 0.0048
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0023 0.0048
Schistosoma mansoni hypothetical protein 0.0979 0.4645 0.6927
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0018 0.0023 0.0023
Echinococcus granulosus GPCR family 2 0.0031 0.0089 0.0089
Trypanosoma cruzi WLM domain containing protein, putative 0.0348 0.1613 1
Onchocerca volvulus 0.0058 0.0215 0.0414
Loa Loa (eye worm) transcription factor SMAD2 0.036 0.1668 0.3591
Trichomonas vaginalis set domain proteins, putative 0.0477 0.2231 0.4802
Schistosoma mansoni zinc finger protein 0.0018 0.0023 0.0019
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Chlamydia trachomatis SWIB complex protein 0.0979 0.4645 0.5
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0076 0.0303 0.0303
Schistosoma mansoni ap endonuclease 0.0019 0.0027 0.0025
Loa Loa (eye worm) nuclear factor I 0.0014 0.0003 0.0007
Trichomonas vaginalis ankyrin, putative 0.0018 0.0023 0.0048
Trichomonas vaginalis hypothetical protein 0.0018 0.0023 0.0048
Loa Loa (eye worm) hypothetical protein 0.0122 0.0526 0.1132
Schistosoma mansoni smad1 5 8 and 0.0025 0.0056 0.0068
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0115 0.0156
Loa Loa (eye worm) hypothetical protein 0.0027 0.0066 0.0142
Echinococcus multilocularis tumor protein p63 0.2092 1 1
Brugia malayi hypothetical protein 0.0037 0.0114 0.0239
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.0473 0.0988
Schistosoma mansoni hypothetical protein 0.0171 0.0758 0.1118
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0016 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0348 0.1613 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0076 0.0303 0.0303
Schistosoma mansoni voltage-gated potassium channel 0.0083 0.0337 0.0487
Trypanosoma brucei ring finger containing protein 0.0018 0.0023 0.0048
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0414 0.0885
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0348 0.1613 1
Toxoplasma gondii exonuclease III APE 0.0019 0.0027 0.0025
Entamoeba histolytica hypothetical protein 0.0037 0.0114 1
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0058 0.0265
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0018 0.0023 0.0048
Brugia malayi Cytochrome P450 family protein 0.0025 0.0058 0.0118
Plasmodium vivax DNA repair protein RAD5, putative 0.0018 0.0023 0.0016
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0348 0.1613 1
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0018 0.0023 0.0048
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Brugia malayi hypothetical protein 0.0234 0.1063 0.2282
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0027 0.044
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0023 0.0019
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0018 0.0023 0.0048
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0027 0.0073
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0114 0.0114
Trichomonas vaginalis ankyrin, putative 0.0018 0.0023 0.0048
Brugia malayi brahma associated protein 60 kDa 0.0979 0.4645 1
Loa Loa (eye worm) beta-lactamase 0.0037 0.0115 0.0248
Echinococcus granulosus cell growth regulator with ring finger domain 0.0018 0.0023 0.0023
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0016
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.001 0.0023
Echinococcus multilocularis microtubule associated protein 2 0.1406 0.6702 0.6702
Schistosoma mansoni RNA binding protein 0.0348 0.1613 0.2395
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.001 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0083 0.0337 0.0487
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0058 0.0125
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0414 0.0885
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0233 0.0332
Schistosoma mansoni hypothetical protein 0.0819 0.3879 0.5782
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0027 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Schistosoma mansoni hypothetical protein 0.0068 0.0264 0.0379
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0044 0.005
Leishmania major hypothetical protein, conserved 0.0348 0.1613 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0027 0.0027
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0027 0.0057
Echinococcus granulosus RING finger protein 185 0.0018 0.0023 0.0023
Echinococcus multilocularis RING finger protein 185 0.0018 0.0023 0.0023
Brugia malayi hypothetical protein 0.0301 0.1388 0.2983
Brugia malayi B-box zinc finger family protein 0.0018 0.0023 0.0043
Onchocerca volvulus 0.0027 0.0066 0.0092
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0062 0.0286
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0051
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0279 0.0599
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0233 0.0233
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0018 0.0023 0.0016
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Schistosoma mansoni rnf5 0.0018 0.0023 0.0019
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0018 0.0023 0.0048
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0016 0.0016
Echinococcus multilocularis ring and YY1 binding protein 0.0348 0.1613 0.1613
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0018 0.0023 0.0023
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.1068 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0018 0.0023 0.0048
Echinococcus multilocularis GPCR, family 2 0.0031 0.0089 0.0089
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0979 0.4645 1
Echinococcus granulosus intermediate filament protein 0.0027 0.0066 0.0066
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0027 0.0073
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0056 0.0121
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0027 0.0025
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0027 0.011
Brugia malayi Zinc finger, C2H2 type family protein 0.0018 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0348 0.1613 0.3472
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Loa Loa (eye worm) hypothetical protein 0.0061 0.0233 0.0501
Brugia malayi Smad1 0.0025 0.0056 0.0113
Echinococcus multilocularis ring finger protein 113a 0.0018 0.0023 0.0023
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Leishmania major hypothetical protein, conserved 0.0018 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0348 0.1613 0.3449
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0089 0.0184
Brugia malayi Neuralized family protein 0.0018 0.0023 0.0043
Schistosoma mansoni intermediate filament proteins 0.0027 0.0066 0.0083
Loa Loa (eye worm) Smad1 0.0025 0.0056 0.0121
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0056 0.0068
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0018 0.0023 0.0023
Brugia malayi beta-lactamase family protein 0.0037 0.0115 0.0241
Schistosoma mansoni smad1 5 8 and 0.0025 0.0056 0.0068
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.001 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0058 0.0265
Entamoeba histolytica hypothetical protein 0.0037 0.0114 1
Loa Loa (eye worm) hypothetical protein 0.0348 0.1613 0.3472
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0414 0.0892
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0979 0.4645 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0018 0.0023 0.0048
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0016 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0115 0.0943
Mycobacterium ulcerans beta-lactamase 0.0037 0.0115 0.4282
Schistosoma mansoni fusion 0.0348 0.1613 0.2395
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0027 0.0073
Loa Loa (eye worm) hypothetical protein 0.0122 0.0526 0.1132
Trypanosoma brucei hypothetical protein, conserved 0.0348 0.1613 1
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0018 0.0023 0.0023
Onchocerca volvulus 0.0348 0.1613 0.3438
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0018 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Schistosoma mansoni mind bomb 0.0018 0.0023 0.0019
Echinococcus multilocularis zinc finger protein Ran binding 0.0348 0.1613 0.1613
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0348 0.1613 1
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0248
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0233 0.0332
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0233 0.0468
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0232 0.1355
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.001 0.001
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0031 0.0089 0.0117
Onchocerca volvulus 0.0306 0.1411 0.3002
Mycobacterium ulcerans lipase LipD 0.0037 0.0115 0.4282
Plasmodium vivax hypothetical protein, conserved 0.0979 0.4645 1
Echinococcus granulosus neuropeptide s receptor 0.0465 0.2177 0.2177
Brugia malayi hypothetical protein 0.0018 0.0023 0.0043
Plasmodium vivax zinc finger protein, putative 0.0018 0.0023 0.0016
Brugia malayi hypothetical protein 0.0018 0.0023 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Mycobacterium tuberculosis Conserved protein 0.0037 0.0115 0.0943
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Brugia malayi hypothetical protein 0.0018 0.0023 0.0043
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0018 0.0023 0.0023
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0018 0.0023 0.0023
Leishmania major hypothetical protein, conserved 0.0037 0.0115 0.0621
Schistosoma mansoni hypothetical protein 0.0018 0.0023 0.0019
Loa Loa (eye worm) hypothetical protein 0.0099 0.0414 0.0892
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0233 0.0233
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0115 0.0246
Brugia malayi hypothetical protein 0.0026 0.0062 0.0125
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0056 0.0056
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0056 0.0056
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0044 0.005
Echinococcus multilocularis SWI:SNF matrix associated 0.0979 0.4645 0.4645
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0232 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0018 0.0011
Leishmania major hypothetical protein, conserved 0.0348 0.1613 1
Leishmania major hypothetical protein, conserved 0.0348 0.1613 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0044 0.0044
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0018 0.0023 0.0016
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0027 0.0052
Schistosoma mansoni lamin 0.0027 0.0066 0.0083
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0062 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.001 0.001
Plasmodium vivax trophozoite exported protein 1, putative 0.0018 0.0023 0.0016
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0348 0.1613 0.3467
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0348 0.1613 0.1613
Schistosoma mansoni hypothetical protein 0.0031 0.0089 0.0117
Echinococcus multilocularis lamin dm0 0.0027 0.0066 0.0066
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0018 0.0023 0.0048
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0027 0.0059
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0979 0.4645 1
Schistosoma mansoni lamin 0.0027 0.0066 0.0083
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0348 0.1613 0.3467
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0018 0.0023 0.0048
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0348 0.1613 0.3467
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Onchocerca volvulus 0.0037 0.0115 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Trypanosoma cruzi hypothetical protein 0.0018 0.0023 0.0048
Leishmania major cytochrome p450-like protein 0.0025 0.0058 0.0265
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0033 0.0064
Trypanosoma brucei predicted zinc finger protein 0.0018 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048
Echinococcus multilocularis SWI:SNF matrix associated 0.0979 0.4645 0.4645
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.001 0.002
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0018 0.0023 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0048

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 37 uM In vitro inhibitory activity against colon carcinoma HT-29 cells after 72 hr using in-house program ChEMBL. No reference
EC50 (functional) = 37 uM In vitro inhibitory activity against colon carcinoma HT-29 cells after 72 hr using in-house program ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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