Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.0229 | 0.1404 |
Loa Loa (eye worm) | hypothetical protein | 0.0634 | 0.078 | 0.0869 |
Mycobacterium ulcerans | polyketide synthase | 0.4371 | 0.558 | 0.6998 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Leishmania major | quinone oxidoreductase, putative | 0.0257 | 0.0295 | 0.1878 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0295 | 0.0322 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.1037 | 0.1297 | 0.8284 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.4115 | 0.525 | 0.6567 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.4004 | 0.5108 | 0.6413 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0257 | 0.0295 | 0.0295 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.4004 | 0.5108 | 0.6413 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.4115 | 0.525 | 0.525 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) | 0.0257 | 0.0295 | 0.0173 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase Adh | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0425 | 0.0512 | 0.0453 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.4372 | 0.5581 | 1 |
Onchocerca volvulus | 0.0257 | 0.0295 | 0.0069 | |
Leishmania major | acyl carrier protein, putative | 0.0417 | 0.0502 | 0.3199 |
Echinococcus multilocularis | Malonyl coenzyme A acyl carrier protein transacylase | 0.0261 | 0.0301 | 0.1899 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0103 | 0.0104 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.4371 | 0.558 | 0.6998 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0203 | 0.0227 | 0.1393 |
Echinococcus granulosus | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0257 | 0.0295 | 0.1864 |
Brugia malayi | Phosphopantetheine attachment site family protein | 0.0417 | 0.0502 | 0.0502 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0035 | 0.0012 | 0.0012 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.1878 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 0.0232 | 0.0232 |
Mycobacterium ulcerans | dehydrogenase | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium ulcerans | thioesterase | 0.3442 | 0.4386 | 0.5436 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.3308 | 0.4214 | 0.5211 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.3308 | 0.4214 | 0.5211 |
Loa Loa (eye worm) | phosphopantetheine attachment site family protein | 0.0417 | 0.0502 | 0.0555 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0417 | 0.0502 | 0.3214 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.0229 | 0.1404 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0418 | 0.0503 | 0.9403 |
Onchocerca volvulus | 0.0425 | 0.0512 | 0.0301 | |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0207 | 0.0232 | 0.1446 |
Brugia malayi | Importin beta-1 subunit | 0.0035 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0372 | 0.0443 | 0.0489 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1244 | 0.1564 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0106 | 0.0103 | 0.0601 |
Plasmodium falciparum | carbonic anhydrase | 0.011 | 0.0107 | 0.0752 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.0257 | 0.0295 | 0.2264 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Leishmania major | NADP-dependent alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.1878 |
Echinococcus multilocularis | snurportin 1 | 0.0372 | 0.0443 | 0.2832 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0425 | 0.0512 | 0.0453 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.4115 | 0.525 | 0.6538 |
Mycobacterium ulcerans | acyl carrier protein | 0.0417 | 0.0502 | 0.0353 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0257 | 0.0295 | 0.2264 |
Brugia malayi | CHE-14 protein | 0.0046 | 0.0025 | 0.0025 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.4371 | 0.558 | 0.6998 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.0301 | 0.0328 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.4371 | 0.558 | 0.6973 |
Schistosoma mansoni | acetylcholinesterase | 0.0207 | 0.0232 | 0.1423 |
Echinococcus granulosus | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Leishmania major | zinc binding dehydrogenase-like protein | 0.0257 | 0.0295 | 0.1878 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.4115 | 0.525 | 0.6598 |
Schistosoma mansoni | gliotactin | 0.0207 | 0.0232 | 0.1423 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.2716 | 0.3454 | 0.4168 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.2967 | 0.3776 | 0.4687 |
Mycobacterium ulcerans | oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Echinococcus granulosus | Malonyl coenzyme A acyl carrier protein transacylase | 0.0261 | 0.0301 | 0.1899 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0023 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0103 | 0.0104 |
Mycobacterium leprae | conserved hypothetical protein | 0.0417 | 0.0502 | 0.0272 |
Loa Loa (eye worm) | alcohol dehydrogenase class III | 0.0257 | 0.0295 | 0.0322 |
Echinococcus multilocularis | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0025 | 0.0016 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.6158 | 0.7874 | 1 |
Onchocerca volvulus | 0.3866 | 0.4932 | 0.5056 | |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.4115 | 0.525 | 0.6567 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0107 | 0.0109 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.1037 | 0.1297 | 0.1394 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.5504 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.2716 | 0.3454 | 0.4216 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2264 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.127 | 0.1597 | 0.1786 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.1037 | 0.1297 | 1 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase | 0.0257 | 0.0295 | 0.0083 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0112 | 0.0109 | 0.0635 |
Mycobacterium tuberculosis | Conserved protein | 0.1244 | 0.1564 | 0.1818 |
Echinococcus granulosus | snurportin 1 | 0.0372 | 0.0443 | 0.2832 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0295 | 0.0322 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0112 | 0.0109 | 0.0646 |
Mycobacterium tuberculosis | S-nitrosomycothiol reductase MscR | 0.0257 | 0.0295 | 0.0173 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0046 | 0.0025 | 0.0146 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0203 | 0.0227 | 0.1682 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0417 | 0.0502 | 0.044 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0425 | 0.0512 | 0.0512 |
Echinococcus granulosus | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0203 | 0.0227 | 0.1736 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.4371 | 0.558 | 0.6973 |
Schistosoma mansoni | carbonic anhydrase-related | 0.011 | 0.0107 | 0.0623 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0417 | 0.0502 | 0.3816 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0203 | 0.0227 | 0.0227 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.1037 | 0.1297 | 0.8293 |
Brugia malayi | AMP-binding enzyme family protein | 0.3866 | 0.4932 | 0.4932 |
Trypanosoma brucei | Trans-2-enoyl-ACP reductase 2, putative | 0.0257 | 0.0295 | 0.2213 |
Onchocerca volvulus | 0.0257 | 0.0295 | 0.0069 | |
Echinococcus granulosus | carboxylesterase 5A | 0.1224 | 0.1538 | 1 |
Mycobacterium tuberculosis | Hypothetical protein | 0.1244 | 0.1564 | 0.1818 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0257 | 0.0295 | 0.2264 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0019 | 0.0105 |
Leishmania major | carbonic anhydrase-like protein | 0.0203 | 0.0227 | 0.144 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.3866 | 0.4932 | 0.6185 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.1037 | 0.1297 | 0.1297 |
Toxoplasma gondii | quinone oxidoreductase, putative | 0.0257 | 0.0295 | 0.0511 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.011 | 0.0107 | 0.0107 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.011 | 0.0107 | 0.0107 |
Brugia malayi | Carboxylesterase family protein | 0.1224 | 0.1538 | 0.1538 |
Echinococcus granulosus | carbonic anhydrase II | 0.0203 | 0.0227 | 0.1417 |
Mycobacterium ulcerans | hypothetical protein | 0.0417 | 0.0502 | 0.0353 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0257 | 0.0295 | 0.2264 |
Mycobacterium tuberculosis | Probable NADP-dependent alcohol dehydrogenase AdhC | 0.0257 | 0.0295 | 0.0173 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0203 | 0.0227 | 0.0227 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0041 | 0.0019 | 0.0062 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.1878 |
Chlamydia trachomatis | acyl carrier protein | 0.0417 | 0.0502 | 0.2016 |
Schistosoma mansoni | carbonic anhydrase | 0.011 | 0.0107 | 0.0623 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2264 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.1297 | 0.1632 | 0.1906 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0418 | 0.0503 | 0.0442 |
Plasmodium vivax | hypothetical protein, conserved | 0.0592 | 0.0726 | 0.5561 |
Echinococcus multilocularis | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Wolbachia endosymbiont of Brugia malayi | ACP S-malonyltransferase | 0.0261 | 0.0301 | 0.0053 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.4115 | 0.525 | 0.6567 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0207 | 0.0232 | 0.1446 |
Mycobacterium tuberculosis | Acyl carrier protein (ACP) MbtL | 0.0417 | 0.0502 | 0.044 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.4371 | 0.558 | 0.6973 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0107 | 0.0109 |
Echinococcus granulosus | neuroligin | 0.0207 | 0.0232 | 0.1446 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.4371 | 0.558 | 0.7025 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 0.0232 | 0.0232 |
Mycobacterium ulcerans | NADPH quinone oxidoreductase FadB4 | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.011 | 0.0107 | 0.0107 |
Schistosoma mansoni | alcohol dehydrogenase | 0.0257 | 0.0295 | 0.1833 |
Mycobacterium tuberculosis | Probable alcohol dehydrogenase AdhA | 0.0257 | 0.0295 | 0.0173 |
Onchocerca volvulus | Acyl carrier protein, mitochondrial homolog | 0.0417 | 0.0502 | 0.0291 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0153 | 0.0163 | 0.0996 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0046 | 0.0025 | 0.0094 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0041 | 0.0019 | 0.0062 |
Mycobacterium ulcerans | zinc-type alcohol dehydrogenase AdhD | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.6158 | 0.7874 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Trypanosoma cruzi | acyl transferase-like protein, putative | 0.0261 | 0.0301 | 0.2305 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase | 0.0418 | 0.0503 | 0.0355 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD-dependent AdhB | 0.0257 | 0.0295 | 0.0083 |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0417 | 0.0502 | 0.3214 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0203 | 0.0227 | 0.1736 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.1037 | 0.1297 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0035 | 0.0012 | 0.0012 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium tuberculosis | Probable acyl carrier protein AcpA (ACP) | 0.0417 | 0.0502 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Echinococcus granulosus | acetylcholinesterase | 0.1224 | 0.1538 | 1 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.1037 | 0.1297 | 1 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.1037 | 0.1297 | 0.1394 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0425 | 0.0512 | 0.0285 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0112 | 0.0109 | 0.0109 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0041 | 0.0019 | 0.0062 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.1037 | 0.1297 | 0.1454 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.1037 | 0.1297 | 0.8422 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0023 | 0.0079 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0107 | 0.0104 | 0.0609 |
Schistosoma mansoni | methyltransferase-related | 0.1244 | 0.1564 | 1 |
Toxoplasma gondii | hypothetical protein | 0.011 | 0.0107 | 0.0174 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0338 | 0.0401 | 0.2552 |
Toxoplasma gondii | Zn-containing alcohol dehydrogenase | 0.0257 | 0.0295 | 0.0511 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0041 | 0.0019 | 0.0014 |
Leishmania major | oxidoreductase-like protein | 0.0257 | 0.0295 | 0.1878 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.1037 | 0.1297 | 0.1394 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Echinococcus granulosus | muscleblind protein | 0.0106 | 0.0103 | 0.0601 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0023 | 0.0079 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.2679 | 0.3407 | 0.6097 |
Onchocerca volvulus | 0.7196 | 0.9208 | 0.9656 | |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.4371 | 0.558 | 0.7025 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0425 | 0.0512 | 0.0366 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0425 | 0.0512 | 0.0366 |
Brugia malayi | hypothetical protein | 0.0207 | 0.0232 | 0.0232 |
Mycobacterium ulcerans | acyl carrier protein | 0.0417 | 0.0502 | 0.0353 |
Onchocerca volvulus | Putative alcohol dehydrogenase | 0.0257 | 0.0295 | 0.0069 |
Mycobacterium ulcerans | oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Treponema pallidum | acyl carrier protein | 0.0417 | 0.0502 | 0.5 |
Leishmania major | zinc-binding dehydrogenase-like protein | 0.0257 | 0.0295 | 0.1878 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.0257 | 0.0295 | 0.0083 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.2716 | 0.3454 | 0.4216 |
Toxoplasma gondii | type I fatty acid synthase | 0.0634 | 0.078 | 0.138 |
Loa Loa (eye worm) | acyl carrier protein | 0.1899 | 0.2405 | 0.2706 |
Mycobacterium ulcerans | oxidoreductase FadB5 | 0.0257 | 0.0295 | 0.0083 |
Echinococcus multilocularis | geminin | 0.0205 | 0.0229 | 0.1428 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0884 | 0.1101 | 0.7136 |
Echinococcus multilocularis | mitochondrial trans 2 enoyl coenzyme A reductase | 0.0257 | 0.0295 | 0.1864 |
Leishmania major | hypothetical protein, conserved | 0.0261 | 0.0301 | 0.1912 |
Plasmodium falciparum | malonyl CoA-acyl carrier protein transacylase | 0.0261 | 0.0301 | 0.2255 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0107 | 0.0104 | 0.1906 |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0417 | 0.0502 | 0.0502 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.1878 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0041 | 0.0019 | 0.0127 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0261 | 0.0301 | 0.1868 |
Loa Loa (eye worm) | carboxylesterase | 0.0207 | 0.0232 | 0.025 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0207 | 0.0232 | 0.009 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0257 | 0.0295 | 0.0295 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0207 | 0.0232 | 0.1446 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0207 | 0.0232 | 0.009 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks3 | 0.0634 | 0.078 | 0.0801 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0012 | 0.0001 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0261 | 0.0301 | 0.1868 |
Loa Loa (eye worm) | hypothetical protein | 0.1224 | 0.1538 | 0.1727 |
Loa Loa (eye worm) | hypothetical protein | 0.2299 | 0.2918 | 0.3286 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.3442 | 0.4386 | 0.5477 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0295 | 0.0322 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0153 | 0.0163 | 0.0996 |
Echinococcus multilocularis | muscleblind protein | 0.0106 | 0.0103 | 0.0601 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.127 | 0.1597 | 0.186 |
Trypanosoma cruzi | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2264 |
Trypanosoma brucei | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2213 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.1297 | 0.1632 | 0.1833 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0019 | 0.0009 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0425 | 0.0512 | 0.0453 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Schistosoma mansoni | zinc binding dehydrogenase | 0.0257 | 0.0295 | 0.1833 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.1037 | 0.1297 | 0.8422 |
Schistosoma mansoni | [ACP] S-malonyltransferase | 0.0261 | 0.0301 | 0.1868 |
Mycobacterium tuberculosis | Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) | 0.0257 | 0.0295 | 0.0173 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0257 | 0.0295 | 0.0173 |
Leishmania major | oxidoreductase, putative | 0.0257 | 0.0295 | 0.1878 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0634 | 0.078 | 0.0801 |
Leishmania major | d-xylulose reductase, putative | 0.0257 | 0.0295 | 0.1878 |
Wolbachia endosymbiont of Brugia malayi | acyl carrier protein | 0.0417 | 0.0502 | 0.2059 |
Toxoplasma gondii | acyl transferase domain-containing protein | 0.0261 | 0.0301 | 0.0521 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0112 | 0.0109 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0295 | 0.0322 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.3866 | 0.4932 | 0.5562 |
Echinococcus multilocularis | expressed conserved protein | 0.0101 | 0.0095 | 0.0555 |
Mycobacterium leprae | PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 | 0.0634 | 0.078 | 0.0639 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.3362 | 0.4284 | 0.5345 |
Mycobacterium tuberculosis | Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) | 0.0257 | 0.0295 | 0.0173 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.1037 | 0.1297 | 0.231 |
Mycobacterium tuberculosis | Possible dehydrogenase | 0.0257 | 0.0295 | 0.0173 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0112 | 0.0109 | 0.0635 |
Trypanosoma brucei | oxidoreductase, putative | 0.0257 | 0.0295 | 0.2213 |
Echinococcus granulosus | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.4115 | 0.525 | 0.6598 |
Mycobacterium tuberculosis | Possible dehydrogenase | 0.0257 | 0.0295 | 0.0173 |
Echinococcus granulosus | geminin | 0.0205 | 0.0229 | 0.1428 |
Loa Loa (eye worm) | carboxylesterase | 0.1224 | 0.1538 | 0.1727 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1224 | 0.1538 | 0.1727 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.011 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.1224 | 0.1538 | 0.1727 |
Leishmania major | nuclear receptor binding factor-like protein | 0.0257 | 0.0295 | 0.1878 |
Mycobacterium leprae | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0418 | 0.0503 | 0.0274 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0207 | 0.0232 | 0.1446 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0046 | 0.0025 | 0.0094 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0207 | 0.0232 | 0.009 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0041 | 0.0019 | 0.0127 |
Giardia lamblia | Methyltransferase like 2 | 0.1244 | 0.1564 | 0.5 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0203 | 0.0227 | 0.1393 |
Mycobacterium ulcerans | Zn-dependent alcohol dehydrogenase, AdhX | 0.0257 | 0.0295 | 0.0083 |
Brugia malayi | Methyltransferase-like protein 4 | 0.1244 | 0.1564 | 0.1564 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0634 | 0.078 | 0.0801 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 0.0232 | 0.0232 |
Echinococcus granulosus | expressed conserved protein | 0.0101 | 0.0095 | 0.0555 |
Schistosoma mansoni | carbonic anhydrase-related | 0.011 | 0.0107 | 0.0623 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0207 | 0.0232 | 0.1469 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.3308 | 0.4214 | 0.5171 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0019 | 0.0019 |
Brugia malayi | Alcohol dehydrogenase class III | 0.0257 | 0.0295 | 0.0295 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.0257 | 0.0295 | 0.2264 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase AdhC | 0.0257 | 0.0295 | 0.0083 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.2088 | 0.2648 | 0.4734 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0203 | 0.0227 | 0.0245 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1224 | 0.1538 | 0.9836 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0207 | 0.0232 | 0.1446 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0112 | 0.0109 | 0.0635 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0203 | 0.0227 | 0.1417 |
Mycobacterium tuberculosis | Possible oxidoreductase FadB5 | 0.0257 | 0.0295 | 0.0173 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.6158 | 0.7874 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0104 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0023 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Schistosoma mansoni | patched 1 | 0.0046 | 0.0025 | 0.0093 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.6158 | 0.7874 | 1 |
Plasmodium falciparum | acyl carrier protein | 0.0417 | 0.0502 | 0.3816 |
Schistosoma mansoni | hypothetical protein | 0.0417 | 0.0502 | 0.3162 |
Brugia malayi | RNA, U transporter 1 | 0.0099 | 0.0093 | 0.0093 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.0257 | 0.0295 | 0.5504 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.3442 | 0.4386 | 0.5398 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0425 | 0.0512 | 0.0366 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks4 | 0.0634 | 0.078 | 0.0801 |
Mycobacterium ulcerans | NADP-dependent oxidoreductase | 0.0257 | 0.0295 | 0.0083 |
Echinococcus multilocularis | AMP dependent ligase | 0.0418 | 0.0503 | 0.3223 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0107 | 0.0104 | 0.0104 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.0257 | 0.0295 | 0.2264 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0417 | 0.0502 | 0.3857 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.4115 | 0.525 | 0.6538 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.1297 | 0.1632 | 0.1764 |
Echinococcus multilocularis | NADH dehydrogenase | 0.0417 | 0.0502 | 0.3214 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0417 | 0.0502 | 0.0881 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0207 | 0.0232 | 0.1469 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.4115 | 0.525 | 0.6598 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.7445 | 0.9528 | 1 |
Plasmodium vivax | malonyl CoA-acyl carrier protein transacylase precursor, putative | 0.0261 | 0.0301 | 0.2255 |
Echinococcus multilocularis | neuroligin | 0.0207 | 0.0232 | 0.1446 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0046 | 0.0025 | 0.0094 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0107 | 0.0104 | 0.0609 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Brugia malayi | Muscleblind-like protein | 0.0106 | 0.0103 | 0.0103 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0107 | 0.0623 |
Mycobacterium tuberculosis | Probable alcohol dehydrogenase Adh | 0.0257 | 0.0295 | 0.0173 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0257 | 0.0295 | 0.0295 |
Loa Loa (eye worm) | fatty acid synthase | 0.4075 | 0.52 | 0.5865 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0338 | 0.0401 | 0.2552 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0425 | 0.0512 | 0.0453 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0109 | 0.0106 | 0.0613 |
Schistosoma mansoni | acyl carrier protein | 0.0417 | 0.0502 | 0.3162 |
Loa Loa (eye worm) | hypothetical protein | 0.0634 | 0.078 | 0.0869 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0112 | 0.0109 | 0.0111 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase AdhE2 | 0.0257 | 0.0295 | 0.0083 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0207 | 0.0232 | 0.1446 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0112 | 0.0109 | 0.0646 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0425 | 0.0512 | 0.0366 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.1404 | 0.177 | 0.2084 |
Mycobacterium ulcerans | malonyl CoA-acyl carrier protein transacylase FabD | 0.0261 | 0.0301 | 0.009 |
Plasmodium vivax | acyl carrier protein, putative | 0.0417 | 0.0502 | 0.3816 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0038 | 0.0031 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.011 | 0.0107 | 0.0109 |
Trypanosoma cruzi | acyl transferase-like protein | 0.0261 | 0.0301 | 0.2305 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0035 | 0.0012 | 0.0001 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.167 | 0.2111 | 0.2527 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.1037 | 0.1297 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0592 | 0.0726 | 0.5561 |
Echinococcus multilocularis | carbonic anhydrase | 0.011 | 0.0107 | 0.0633 |
Schistosoma mansoni | hypothetical protein | 0.0372 | 0.0443 | 0.2786 |
Loa Loa (eye worm) | carboxylesterase | 0.0207 | 0.0232 | 0.025 |
Echinococcus multilocularis | acetylcholinesterase | 0.1224 | 0.1538 | 1 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.294 | 0.3742 | 0.6698 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1224 | 0.1538 | 1 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.1037 | 0.1297 | 1 |
Leishmania major | hypothetical protein, conserved | 0.1244 | 0.1564 | 1 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.1037 | 0.1297 | 1 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.1009 | 0.1262 | 0.1426 |
Mycobacterium ulcerans | thioesterase TesA | 0.3442 | 0.4386 | 0.5436 |
Echinococcus multilocularis | acetylcholinesterase | 0.1224 | 0.1538 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.011 | 0.0107 | 0.0107 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0425 | 0.0512 | 0.0366 |
Loa Loa (eye worm) | acyl carrier protein | 0.0417 | 0.0502 | 0.0555 |
Schistosoma mansoni | carbonic anhydrase-related | 0.011 | 0.0107 | 0.0623 |
Mycobacterium tuberculosis | Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) | 0.0257 | 0.0295 | 0.0173 |
Echinococcus granulosus | acetylcholinesterase | 0.1224 | 0.1538 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0207 | 0.0232 | 0.0232 |
Echinococcus granulosus | AMP dependent ligase | 0.0418 | 0.0503 | 0.3223 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.4115 | 0.525 | 0.6567 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0046 | 0.0025 | 0.0016 |
Brugia malayi | ADP-specific Phosphofructokinase/Glucokinase conserved region family protein | 0.0261 | 0.0301 | 0.0301 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0207 | 0.0232 | 0.1423 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.4371 | 0.558 | 0.7025 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0203 | 0.0227 | 0.0245 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase | 0.0257 | 0.0295 | 0.5504 |
Brugia malayi | AMP-binding enzyme family protein | 0.1271 | 0.1598 | 0.1598 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.2348 | 0.2982 | 0.3656 |
Mycobacterium ulcerans | quinone reductase Qor | 0.0257 | 0.0295 | 0.0083 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.1037 | 0.1297 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0041 | 0.0019 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.0232 | 0.025 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0443 | 0.0535 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase FadD9 | 0.0418 | 0.0503 | 0.0355 |
Mycobacterium ulcerans | polyketide synthase | 0.4115 | 0.525 | 0.6567 |
Brugia malayi | Carboxylesterase family protein | 0.1224 | 0.1538 | 0.1538 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0107 | 0.0109 |
Echinococcus granulosus | NADH dehydrogenase | 0.0417 | 0.0502 | 0.3214 |
Echinococcus multilocularis | protein dispatched 1 | 0.0053 | 0.0033 | 0.0149 |
Trypanosoma brucei | acyl transferase-like protein | 0.0261 | 0.0301 | 0.2255 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0112 | 0.0109 | 0.0646 |
Mycobacterium tuberculosis | Meromycolate extension acyl carrier protein AcpM | 0.0417 | 0.0502 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.6924 | 0.8858 | 1 |
Echinococcus multilocularis | protein patched | 0.0046 | 0.0025 | 0.0094 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.