Detailed information for compound 1798486

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 265.393 | Formula: C19H23N
  • H donors: 1 H acceptors: 0 LogP: 4.69 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: C([C@@H]1C[C@@H](N1)CCc1ccccc1)Cc1ccccc1
  • InChi: 1S/C19H23N/c1-3-7-16(8-4-1)11-13-18-15-19(20-18)14-12-17-9-5-2-6-10-17/h1-10,18-20H,11-15H2/t18-,19+
  • InChiKey: ROSVKMDXTPQTKS-KDURUIRLSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0023 0.0023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0856 0.3782 0.3782
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0407 0.076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.1278 1
Toxoplasma gondii isocitrate dehydrogenase 0.0051 0.0158 0.3543
Schistosoma mansoni single-minded 0.0016 0.0001 0.0001
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0023 0.0023
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0025 0.0041
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1183 0.5257 0.9829
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0426 0.0426
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.002 0.0019 0.0036
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0255 0.116
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0066 0.0066
Trypanosoma cruzi heat shock protein 90, putative 0.0035 0.0084 0.0156
Leishmania major protein kinase, putative 0.0016 0.0001 0.0001
Onchocerca volvulus Protein UBASH3A homolog 0.002 0.0019 0.0033
Echinococcus granulosus heat shock protein 90 0.0035 0.0084 0.0084
Trypanosoma brucei Heat shock protein 83, putative 0.0035 0.0084 0.0156
Trypanosoma brucei unspecified product 0.0041 0.0115 0.0213
Echinococcus multilocularis isocitrate dehydrogenase 0.0051 0.0158 0.0158
Schistosoma mansoni microtubule-associated protein tau 0.2236 1 1
Giardia lamblia Fructose-bisphosphate aldolase 0.03 0.1278 0.4065
Brugia malayi Pre-SET motif family protein 0.0031 0.0066 0.0298
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0012 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0023 0.0104
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0044 0.279
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0588 1
Echinococcus granulosus phosphoglycerate mutase 0.002 0.0019 0.0019
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0017 0.0005 0.0005
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0012 0.0022
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0044 0.279
Echinococcus multilocularis aryl hydrocarbon receptor 0.0055 0.0175 0.0175
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.1183 0.5257 0.9829
Echinococcus granulosus intermediate filament protein 0.006 0.0196 0.0196
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0079 0.0148
Mycobacterium tuberculosis Conserved hypothetical protein 0.006 0.0199 0.2925
Brugia malayi Cathepsin L-like precursor 0.0016 0.0002 0.0007
Leishmania major hypothetical protein, unknown function 0.002 0.0019 0.0036
Schistosoma mansoni heat shock protein 0.0035 0.0084 0.0084
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0044 0.0988
Leishmania major DNA polymerase eta, putative 0.0073 0.0256 0.0479
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0407 0.185
Echinococcus multilocularis transcription factor eb 0.0115 0.0448 0.0448
Echinococcus granulosus transcription factor eb 0.0115 0.0448 0.0448
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.002 0.0019 0.0315
Brugia malayi Muscleblind-like protein 0.03 0.1279 0.582
Toxoplasma gondii heat shock protein 90, putative 0.0035 0.0084 0.1879
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.0082
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.0513 0.2241 0.4189
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0023 0.0023
Brugia malayi steroid hormone receptor 0.0021 0.0023 0.0104
Loa Loa (eye worm) histone methyltransferase 0.002 0.0016 0.003
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0199 0.0599
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0066 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.002 0.0019 0.0036
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0063 0.0116
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0028 0.0052 0.0536
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.1264 0.2363
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0145
Onchocerca volvulus 0.002 0.0019 0.0033
Mycobacterium leprae Possible phosphoglycerate mutase 0.002 0.0019 0.0315
Mycobacterium ulcerans acid phosphatase 0.002 0.0019 0.0024
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0002 0.0104
Trypanosoma brucei glycerolphosphate mutase, putative 0.002 0.0019 0.0036
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.002 0.0019 0.0315
Brugia malayi Cathepsin L-like precursor 0.0016 0.0002 0.0007
Schistosoma mansoni ap endonuclease 0.0021 0.0025 0.0025
Loa Loa (eye worm) cysteine protease 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0098 0.0183
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.002 0.0019 0.0019
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.002 0.0019 0.0036
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.006 0.0199 0.0199
Plasmodium vivax phosphoglucomutase-2, putative 0.002 0.0019 0.1208
Onchocerca volvulus 0.006 0.0199 0.0368
Loa Loa (eye worm) hypothetical protein 0.0029 0.0057 0.0107
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.002 0.0019 0.0056
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0063 0.0483
Leishmania major protein kinase, putative 0.0016 0.0001 0.0001
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0063 0.3947
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0039 0.0102 0.0461
Trypanosoma brucei unspecified product 0.0041 0.0115 0.0213
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0084 0.0156
Plasmodium vivax vivapain-2 0.0016 0.0002 0.0104
Schistosoma mansoni hypothetical protein 0.0034 0.0079 0.0079
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0242 0.0739
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0199 0.1547
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.002 0.0019 0.0036
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0158 0.0295
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0115 0.0213
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0199 0.037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0023 0.0104
Echinococcus multilocularis dna polymerase kappa 0.006 0.0199 0.0199
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.1203 0.5349 0.5349
Echinococcus multilocularis phosphoglycerate mutase 0.002 0.0019 0.0019
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0002 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.013 0.013
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0012 0.0022
Schistosoma mansoni hypothetical protein 0.0521 0.2274 0.2274
Plasmodium vivax phosphoglycerate mutase, putative 0.002 0.0019 0.1208
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0023 0.0023
Echinococcus multilocularis microtubule associated protein 2 0.2236 1 1
Toxoplasma gondii phosphoglycerate mutase family protein 0.002 0.0019 0.0428
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0055 0.0055
Echinococcus granulosus heat shock protein 90 0.0028 0.0052 0.0052
Brugia malayi hypothetical protein 0.0017 0.0003 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0199 0.0371
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.056 0.1047
Brugia malayi nuclear hormone receptor 0.0021 0.0023 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.1278 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0066 0.0066
Echinococcus granulosus phosphoglycerate mutase 0.002 0.0019 0.0019
Mycobacterium ulcerans hypothetical protein 0.002 0.0019 0.0024
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0051 0.0158 0.0158
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0039 0.0102 0.019
Loa Loa (eye worm) hypothetical protein 0.0106 0.0407 0.076
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.071 0.3127 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0025 0.0073
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.002 0.0019 0.0036
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0058 0.0191 0.0357
Entamoeba histolytica Flap nuclease, putative 0.003 0.0063 0.0194
Echinococcus multilocularis cpg binding protein 0.0063 0.0214 0.0214
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0063 0.0163
Trypanosoma brucei heat shock protein, putative 0.0035 0.0084 0.0156
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0023 0.0043
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0115 0.0444 0.0829
Onchocerca volvulus 0.1203 0.5349 1
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.1183 0.5257 0.9829
Brugia malayi polk-prov protein 0.0019 0.0012 0.0053
Trypanosoma brucei DNA polymerase eta, putative 0.0114 0.0443 0.0828
Onchocerca volvulus Protein UBASH3A homolog 0.002 0.0019 0.0033
Onchocerca volvulus Huntingtin homolog 0.0131 0.0516 0.0962
Echinococcus multilocularis lamin dm0 0.006 0.0196 0.0196
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0002 0.0003
Toxoplasma gondii phosphoglycerate mutase PGMII 0.002 0.0019 0.0428
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0073 0.0256 0.5752
Echinococcus multilocularis musashi 0.006 0.0196 0.0196
Brugia malayi hypothetical protein 0.0038 0.0098 0.0444
Toxoplasma gondii exonuclease III APE 0.0021 0.0025 0.0546
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.0084 0.0262
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0472 0.2055 0.3842
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0158 0.0295
Echinococcus multilocularis flap endonuclease 1 0.003 0.0063 0.0063
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0242 0.3634
Echinococcus multilocularis survival motor neuron protein 1 0.0504 0.2198 0.2198
Entamoeba histolytica hypothetical protein 0.0111 0.0426 0.1357
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0051 0.0158 1
Brugia malayi CXXC zinc finger family protein 0.006 0.0199 0.0902
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0025 0.0045
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0072 0.0324
Toxoplasma gondii phosphoglycerate mutase 0.002 0.0019 0.0428
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Onchocerca volvulus 0.0103 0.0391 0.0727
Onchocerca volvulus 0.0472 0.2055 0.384
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0588 0.1848
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Echinococcus multilocularis heat shock protein 90 0.0035 0.0084 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0158 0.0158
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.1264 0.2363
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0199 0.0902
Trypanosoma brucei heat shock protein, putative 0.0035 0.0084 0.0156
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.021 0.0392
Entamoeba histolytica deoxycytidyl transferase, putative 0.006 0.0199 0.0629
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Leishmania major phosphoglycerate mutase protein, putative 0.002 0.0019 0.0036
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0055 0.0175 0.0326
Schistosoma mansoni DNA polymerase IV / kappa 0.0019 0.0012 0.0012
Onchocerca volvulus 0.0054 0.0171 0.0316
Brugia malayi PAS domain containing protein 0.0016 0.0001 0.0003
Brugia malayi phosphoglycerate mutase family protein 0.002 0.0019 0.0087
Trypanosoma brucei heat shock protein, putative 0.0035 0.0084 0.0156
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0242 0.0242
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0103 0.0391 0.1777
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.002 0.0019 0.0036
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.002 0.0019 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.013 0.013
Entamoeba histolytica hypothetical protein 0.0111 0.0426 0.1357
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.002 0.0019 0.0315
Leishmania major cathepsin L-like protease 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0131 0.0516 0.0965
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.02 0.02
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.056 0.1047
Schistosoma mansoni hypothetical protein 0.0034 0.0079 0.0079
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0116 0.0216
Brugia malayi heat shock protein 90 0.0035 0.0084 0.0381
Loa Loa (eye worm) hypothetical protein 0.1203 0.5349 1
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.071 0.3127 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0507 0.0507
Trypanosoma brucei heat shock protein, putative 0.0035 0.0084 0.0156
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.056 0.1047
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0199 0.0371
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0066 0.1473
Trypanosoma cruzi DNA polymerase eta, putative 0.0073 0.0256 0.0479
Brugia malayi MH2 domain containing protein 0.0127 0.0501 0.228
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.03 0.1278 0.4084
Brugia malayi jmjC domain containing protein 0.006 0.02 0.0907
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0023 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.021 0.0392
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.0501 0.0937
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Trypanosoma brucei heat shock protein, putative 0.0035 0.0084 0.0156
Loa Loa (eye worm) isocitrate dehydrogenase 0.0051 0.0158 0.0295
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0093 0.0346 0.1102
Mycobacterium leprae conserved hypothetical protein 0.002 0.0019 0.0315
Giardia lamblia DINP protein human, muc B family 0.006 0.0199 0.0599
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0023 0.0023
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.021 0.0392
Loa Loa (eye worm) hypothetical protein 0.03 0.1279 0.2391
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.1264 0.2363
Schistosoma mansoni ap endonuclease 0.0021 0.0025 0.0025
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.0084 0.0156
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0063 0.0116
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0023 0.0104
Schistosoma mansoni phosphoglycerate mutase 0.002 0.0019 0.0019
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0052 0.0097
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Schistosoma mansoni hypothetical protein 0.002 0.0019 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0066 0.0066
Echinococcus granulosus aryl hydrocarbon receptor 0.0055 0.0175 0.0175
Plasmodium falciparum DNA repair protein REV1, putative 0.0019 0.0012 0.0732
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0028 0.0052 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0023 0.0023
Brugia malayi nuclear receptor NHR-88 0.0021 0.0023 0.0104
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.015 0.0279
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1203 0.5349 1
Brugia malayi hypothetical protein 0.0131 0.0516 0.2348
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0025 0.0186
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0002 0.0003
Mycobacterium ulcerans phosphoglycerate mutase 0.002 0.0019 0.0024
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.002 0.0019 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.1183 0.5257 0.9829
Schistosoma mansoni cpg binding protein 0.0063 0.0214 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0022
Schistosoma mansoni coup transcription factor 0.0021 0.0023 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0023 0.0104
Loa Loa (eye worm) hypothetical protein 0.0034 0.0079 0.0148
Treponema pallidum fructose-bisphosphate aldolase 0.03 0.1278 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0063 0.1399
Loa Loa (eye worm) endoplasmin 0.0035 0.0084 0.0156
Schistosoma mansoni hypothetical protein 0.0111 0.0426 0.0426
Giardia lamblia Hypothetical protein 0.071 0.3127 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0407 0.185
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0039 0.0102 0.0461
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.0855 0.1598
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0023 0.0023
Giardia lamblia Hypothetical protein 0.071 0.3127 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.006 0.0199 0.0199
Onchocerca volvulus Protein UBASH3A homolog 0.002 0.0019 0.0033
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0002 0.0104
Mycobacterium leprae conserved hypothetical protein 0.002 0.0019 0.0315
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0079 0.0079
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Trypanosoma brucei heat shock protein, putative 0.0035 0.0084 0.0156
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Trypanosoma brucei phosphoglycerate mutase, putative 0.002 0.0019 0.0036
Leishmania major glycerolphosphate mutase, putative 0.002 0.0019 0.0036
Loa Loa (eye worm) ctsf protein 0.0016 0.0002 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0242 0.0242
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0016 0.0016
Echinococcus granulosus 6 phosphofructo 2 kinase:fructose 2 0.1203 0.5349 0.5349
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0023 0.0023
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0023 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0199 0.0371
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1203 0.5349 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0023 0.0023
Leishmania major cathepsin L-like protease 0.0016 0.0002 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0025 0.0045
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0513 0.2241 0.4189
Schistosoma mansoni aryl hydrocarbon receptor 0.0017 0.0005 0.0005
Brugia malayi hypothetical protein 0.0026 0.0044 0.02
Echinococcus multilocularis cysteine protease 0.0016 0.0002 0.0002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0079 0.0079
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Schistosoma mansoni survival motor neuron protein 0.0103 0.0391 0.0391
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.1278 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0036
Onchocerca volvulus 0.002 0.0019 0.0033
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0024 0.0178
Echinococcus multilocularis geminin 0.0521 0.2274 0.2274
Schistosoma mansoni hypothetical protein 0.002 0.0019 0.0019
Toxoplasma gondii hypothetical protein 0.0048 0.0143 0.3215
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0066 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.1278 1
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.002 0.0019 0.0036
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0024 0.0178
Mycobacterium ulcerans hydrolase MutT1 0.002 0.0019 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0023 0.0104
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0023 0.0023
Schistosoma mansoni cpg binding protein 0.006 0.0199 0.0199
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Leishmania major cathepsin L-like protease 0.0016 0.0002 0.0003
Onchocerca volvulus Protein UBASH3A homolog 0.002 0.0019 0.0033
Echinococcus multilocularis Protein lozenge 0.0059 0.0195 0.0195
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0115 0.0448 0.2035
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0044 0.279
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0025 0.1541
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0063 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0199 0.0371
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0012 0.0022
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0002 0.0002
Echinococcus multilocularis phosphoglycerate mutase 0.002 0.0019 0.0019
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.006 0.0199 0.2925
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0023 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0023 0.0104
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.1183 0.5257 0.9829
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0002 0.0009
Schistosoma mansoni hypothetical protein 0.0521 0.2274 0.2274
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0588 0.9276
Onchocerca volvulus Protein cycle homolog 0.0039 0.0102 0.0187
Loa Loa (eye worm) hypothetical protein 0.0038 0.0098 0.0183
Echinococcus granulosus phosphoglycerate mutase 0.002 0.0019 0.0019
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0025 0.1541
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0028 0.0052 0.0875
Leishmania major phosphoglycerate mutase, putative 0.002 0.0019 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0016 0.0016
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.002 0.0019 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.1278 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.03 0.1278 0.4084
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0199 0.0371
Plasmodium vivax SET domain protein, putative 0.0031 0.0066 0.4157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.002 0.0019 0.0036
Schistosoma mansoni hypothetical protein 0.0103 0.0391 0.0391
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0002 0.0002
Brugia malayi hypothetical protein 0.0111 0.0426 0.1938
Brugia malayi jmjC domain containing protein 0.0064 0.0215 0.0977
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0036
Schistosoma mansoni endoplasmin 0.0035 0.0084 0.0084
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0023 0.0104
Toxoplasma gondii phosphoglycerate mutase family protein 0.002 0.0019 0.0428
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0023 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0242 0.0452
Toxoplasma gondii phosphoglycerate mutase family protein 0.002 0.0019 0.0428
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.1264 0.2363
Brugia malayi Cathepsin L-like precursor 0.0016 0.0002 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0632 1
Entamoeba histolytica heat shock protein 90, putative 0.0035 0.0084 0.0262
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0023 0.0104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0001 0.0001
Trypanosoma cruzi glycerolphosphate mutase, putative 0.002 0.0019 0.0036
Schistosoma mansoni jumonji domain containing protein 0.006 0.02 0.02
Leishmania major DNA polymerase kappa, putative 0.006 0.0199 0.0371
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0044 0.0082
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0186 0.0347
Mycobacterium leprae probable isochorismate synthase EntC 0.002 0.0019 0.0315
Leishmania major DNA polymerase eta, putative 0.0114 0.0443 0.0828
Leishmania major hypothetical protein, conserved 0.002 0.0019 0.0036
Mycobacterium ulcerans phosphohistidine phosphatase SixA 0.002 0.0019 0.0024
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Echinococcus multilocularis GPCR, family 2 0.0034 0.0079 0.0079
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1203 0.5349 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.002 0.0019 0.0036
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.002 0.0019 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0038 0.0098 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Schistosoma mansoni hypothetical protein 0.002 0.0019 0.0019
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0145
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0002 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0023 0.0023
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0023 0.004
Toxoplasma gondii heat shock protein HSP90 0.0035 0.0084 0.1879
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1203 0.5349 1
Trichomonas vaginalis set domain proteins, putative 0.0234 0.0982 0.7682
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Echinococcus granulosus dna polymerase eta 0.0114 0.0443 0.0443
Schistosoma mansoni terminal deoxycytidyl transferase 0.006 0.0199 0.0199
Plasmodium falciparum flap endonuclease 1 0.003 0.0063 0.3947
Plasmodium falciparum endoplasmin, putative 0.0021 0.0024 0.1477
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0023 0.0043
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0028 0.0052 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0023 0.0043
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.002 0.0019 0.0315
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0023 0.0023
Onchocerca volvulus 0.0021 0.0023 0.004
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0023 0.0023
Mycobacterium ulcerans lipoprotein LpqD 0.002 0.0019 0.0024
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.002 0.0019 0.0036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0114 0.0443 0.0828
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0445 1
Plasmodium falciparum phosphoglycerate mutase, putative 0.002 0.0019 0.1208
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0052 0.0402
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0199 0.0371
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0079 0.0079
Trypanosoma brucei heat shock protein, putative 0.0035 0.0084 0.0156
Loa Loa (eye worm) runx1 0.0059 0.0195 0.0363
Brugia malayi hypothetical protein 0.0039 0.0102 0.0461
Brugia malayi hypothetical protein 0.0504 0.2198 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.1278 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0116 0.0216
Echinococcus granulosus muscleblind protein 0.03 0.1279 0.1279
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1628 0.7263 0.7263
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.0196 0.0366
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0513 0.2241 0.4189
Echinococcus granulosus phosphoglycerate mutase 0.002 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0115 0.0213
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0023 0.0104
Trichomonas vaginalis phosphoglycerate mutase, putative 0.002 0.0019 0.0145
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0079 0.036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0023 0.0023
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.002 0.0019 0.0019
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Onchocerca volvulus 0.006 0.0196 0.0363
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0012 0.0259
Loa Loa (eye worm) hypothetical protein 0.0038 0.0098 0.0183
Entamoeba histolytica hypothetical protein 0.0111 0.0426 0.1357
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0022
Loa Loa (eye worm) hypothetical protein 0.0115 0.0444 0.0829
Leishmania major hypothetical protein, conserved 0.002 0.0019 0.0036
Brugia malayi Endoplasmin precursor 0.0035 0.0084 0.0381
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0001 0.0001
Brugia malayi hypothetical protein 0.0472 0.2055 0.9352
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.013 0.0591
Plasmodium vivax vivapain-2 0.0016 0.0002 0.0104
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0025 0.0041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0215 0.0215
Loa Loa (eye worm) heat shock protein 90 0.0035 0.0084 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0023 0.0104
Schistosoma mansoni hypothetical protein 0.002 0.0019 0.0019
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0199 0.0599
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.021 0.0392
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.1278 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0016 0.0016
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0242 0.0242
Trypanosoma brucei unspecified product 0.006 0.0199 0.0371
Loa Loa (eye worm) hypothetical protein 0.0073 0.0255 0.0477
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0052 0.0402
Echinococcus multilocularis endoplasmin 0.0028 0.0052 0.0052
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.002 0.0037
Echinococcus granulosus cathepsin l1 0.0016 0.0002 0.0002
Trichomonas vaginalis phosphoglycerate mutase, putative 0.002 0.0019 0.0145
Mycobacterium leprae conserved hypothetical protein 0.002 0.0019 0.0315
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.006 0.0199 0.0371
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0242 0.0739
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.013 0.013
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0023 0.0023
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0426 0.0426
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0158 0.0158
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0002 0.0002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0022
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0215 0.0215
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0051 0.0158 0.0295
Schistosoma mansoni intermediate filament proteins 0.006 0.0196 0.0196
Schistosoma mansoni phosphoglycerate mutase 0.002 0.0019 0.0019
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.002 0.0019 0.0019
Trypanosoma cruzi DNA polymerase eta, putative 0.0114 0.0443 0.0828
Echinococcus granulosus lamin dm0 0.006 0.0196 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0023 0.0104
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0025 0.0025
Schistosoma mansoni lamin 0.006 0.0196 0.0196
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0015 0.0069
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Leishmania major DNA damage repair protein, putative 0.0019 0.0012 0.0022
Trypanosoma cruzi heat shock protein 85, putative 0.0028 0.0052 0.0097
Echinococcus multilocularis lamin 0.006 0.0196 0.0196
Echinococcus granulosus lamin 0.006 0.0196 0.0196
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Schistosoma mansoni hypothetical protein 0.002 0.0019 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0066 0.0066
Brugia malayi Flap endonuclease-1 0.003 0.0063 0.0283
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Echinococcus multilocularis dnaJ subfamily B 0.0856 0.3782 0.3782
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0023 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0044 0.0082
Leishmania major phosphoglycerate mutase family member 5, putative 0.002 0.0019 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Echinococcus multilocularis phosphoglycerate mutase 0.002 0.0019 0.0019
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0001 0.0001
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0023 0.0023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0023 0.0023
Brugia malayi hypothetical protein 0.0054 0.0171 0.0777
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0025 0.0042
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0028 0.0052 1
Loa Loa (eye worm) phosphoglycerate mutase 0.002 0.0019 0.0036
Mycobacterium ulcerans hypothetical protein 0.0156 0.0632 0.199
Schistosoma mansoni cpg binding protein 0.0063 0.0214 0.0214
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0023 0.0104
Toxoplasma gondii isocitrate dehydrogenase 0.0051 0.0158 0.3543
Brugia malayi ImpB/MucB/SamB family protein 0.0114 0.0443 0.2015
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0084 0.0156
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0051 0.0158 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0158 0.0158
Schistosoma mansoni hypothetical protein 0.002 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0002 0.0009
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0199 0.1547
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.02 0.02
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0023 0.0043
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0123
Mycobacterium ulcerans hypothetical protein 0.071 0.3127 1
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Mycobacterium ulcerans hypothetical protein 0.002 0.0019 0.0024
Onchocerca volvulus 0.0031 0.0066 0.012
Giardia lamblia Heat shock protein HSP 90-alpha 0.0035 0.0084 0.0231
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0044 0.0082
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.013 0.0243
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Brugia malayi intermediate filament protein 0.006 0.0196 0.0891
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.006 0.0199 0.0371
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0158 0.0295
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Brugia malayi ecdysteroid receptor 0.0021 0.0023 0.0104
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0023 0.0023
Trypanosoma cruzi heat shock protein 90, putative 0.0028 0.0052 0.0097
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.002 0.0019 0.0036
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0034 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0051 0.0158 0.2264
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0131 0.0516 0.0965
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0002 0.0104
Loa Loa (eye worm) hypothetical protein 0.0028 0.0052 0.0097
Schistosoma mansoni hypothetical protein 0.0073 0.0255 0.0255
Echinococcus granulosus survival motor neuron protein 1 0.0504 0.2198 0.2198
Echinococcus multilocularis muscleblind protein 0.03 0.1279 0.1279
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0115 0.0213
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0025 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0012 0.0022
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0093 0.0346 0.0647
Schistosoma mansoni lozenge 0.0059 0.0195 0.0195
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0426 0.0426
Echinococcus multilocularis phosphoglycerate mutase 0.002 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0504 0.2198 0.4108
Trichomonas vaginalis heat shock protein, putative 0.0028 0.0052 0.0402
Giardia lamblia Grp94/Hsp90 0.0028 0.0052 0.0129
Brugia malayi Cathepsin L-like precursor 0.0016 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0054 0.0171 0.0319
Echinococcus granulosus heat shock protein 0.0035 0.0084 0.0084
Echinococcus multilocularis heat shock protein 0.0035 0.0084 0.0084
Trichomonas vaginalis heat shock protein, putative 0.0035 0.0084 0.0651
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0023 0.0023
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.0501 0.0937
Echinococcus multilocularis phosphoglycerate mutase 0.002 0.0019 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0157 0.0293
Echinococcus multilocularis muscleblind protein 1 0.03 0.1279 0.1279
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0023 0.0043
Trypanosoma cruzi phosphoglycerate mutase, putative 0.002 0.0019 0.0036
Echinococcus granulosus endoplasmin 0.0028 0.0052 0.0052
Toxoplasma gondii cathepsin CPL 0.0016 0.0002 0.0037
Trypanosoma brucei chrX additional, unordered contigs 0.0019 0.0012 0.0022
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0079 0.036
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Giardia lamblia Heat shock protein HSP 90-alpha 0.0028 0.0052 0.0129
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.002 0.0019 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0023 0.0043
Leishmania major cathepsin L-like protease 0.0016 0.0002 0.0003
Schistosoma mansoni DNA polymerase eta 0.0114 0.0443 0.0443
Echinococcus multilocularis dna polymerase eta 0.0114 0.0443 0.0443
Loa Loa (eye worm) intermediate filament protein 0.006 0.0196 0.0366
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0023 0.0043
Leishmania major cathepsin L-like protease 0.0016 0.0002 0.0003
Plasmodium vivax heat shock protein 86, putative 0.0035 0.0084 0.5304
Schistosoma mansoni flap endonuclease-1 0.0027 0.005 0.005
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0017 0.0005 0.0005
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0242 0.5429
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Trichomonas vaginalis phosphoglycerate mutase, putative 0.002 0.0019 0.0145
Echinococcus granulosus dna polymerase kappa 0.006 0.0199 0.0199
Mycobacterium ulcerans phosphoglycerate mutase 0.002 0.0019 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0023 0.0023
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0038 0.0098 0.0444
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0016 0.0016
Brugia malayi Cathepsin L-like precursor 0.0016 0.0002 0.0007
Echinococcus granulosus geminin 0.0521 0.2274 0.2274
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0023 0.0033 1
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0513 0.2241 0.4189
Leishmania major cathepsin L-like protease 0.0063 0.021 0.0392
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.0196 0.0891
Echinococcus multilocularis cysteine protease 0.0016 0.0002 0.0002
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0023 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0002 0.0009
Onchocerca volvulus 0.006 0.0196 0.0363
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Leishmania major hypothetical protein, conserved 0.002 0.0019 0.0036
Trypanosoma cruzi Heat shock protein 83, putative 0.0035 0.0084 0.0156
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.013 0.013
Echinococcus multilocularis heat shock protein 90 0.0028 0.0052 0.0052
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0093 0.0346 0.1102
Onchocerca volvulus 0.002 0.0019 0.0033
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Trichomonas vaginalis phosphoglycerate mutase, putative 0.002 0.0019 0.0145
Leishmania major hypothetical protein, conserved 0.0026 0.0044 0.0082
Loa Loa (eye worm) hypothetical protein 0.006 0.0196 0.0366
Leishmania major heat shock protein 83-1 0.0035 0.0084 0.0156
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0051 0.0158 0.0158
Brugia malayi UBASH3A protein homolog 0.002 0.0019 0.0087
Trypanosoma brucei heat shock protein, putative 0.0035 0.0084 0.0156
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0012 0.0022
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0002 0.0002
Brugia malayi isocitrate dehydrogenase 0.0051 0.0158 0.0718
Trichomonas vaginalis phosphoglycerate mutase, putative 0.002 0.0019 0.0145
Echinococcus granulosus dnaJ subfamily B 0.0856 0.3782 0.3782
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0199 0.0371
Trypanosoma cruzi phosphoglycerate mutase, putative 0.002 0.0019 0.0036
Entamoeba histolytica hypothetical protein 0.0111 0.0426 0.1357
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.002 0.0019 0.0036
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.002 0.0019 0.0019
Brugia malayi phosphoglycerate mutase family protein 0.002 0.0019 0.0087
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0215 0.0401
Schistosoma mansoni lamin 0.006 0.0196 0.0196
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0023 0.0043
Plasmodium vivax endoplasmin, putative 0.0035 0.0084 0.5304
Brugia malayi Isocitrate dehydrogenase 0.0051 0.0158 0.0718
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Leishmania major cathepsin L-like protease 0.0063 0.021 0.0392
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0063 0.0116
Schistosoma mansoni heat shock protein 0.0035 0.0084 0.0084
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0012 0.0022
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0472 0.2055 0.3842
Trypanosoma brucei heat shock protein 90, putative 0.0035 0.0084 0.0156
Mycobacterium ulcerans phosphoglyceromutase 0.002 0.0019 0.0024
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.002 0.0019 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Mycobacterium ulcerans bifunctional RNase H/acid phosphatase 0.002 0.0019 0.0024
Mycobacterium ulcerans heat shock protein 90 0.0028 0.0052 0.0129
Trypanosoma cruzi heat shock protein 85, putative 0.0035 0.0084 0.0156
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0242 0.0739
Echinococcus granulosus GPCR family 2 0.0034 0.0079 0.0079
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.002 0.0019 0.0056
Schistosoma mansoni 6-phosphofructokinase 0.1203 0.5349 0.5349
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0002 0.0003
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0025 0.0045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0002 0.0009
Echinococcus granulosus flap endonuclease 1 0.003 0.0063 0.0063
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.006 0.0199 0.0199
Schistosoma mansoni endoplasmin 0.0035 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.0034 0.0079 0.0079
Trypanosoma cruzi glycerolphosphate mutase, putative 0.002 0.0019 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0023 0.0104
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0025 0.0186
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.002 0.0019 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0023 0.0023
Brugia malayi Cathepsin L-like precursor 0.0016 0.0002 0.0007
Leishmania major DNA polymerase kappa, putative 0.0019 0.0012 0.0022
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0039 0.0102 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Echinococcus multilocularis phosphoglycerate mutase 0.002 0.0019 0.0019
Echinococcus granulosus cpg binding protein 0.0063 0.0214 0.0214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.1278 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0025 0.0086
Plasmodium falciparum heat shock protein 90 0.0035 0.0084 0.5304
Loa Loa (eye worm) hypothetical protein 0.03 0.1279 0.2391
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.013 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Treponema pallidum heat shock protein 90 0.0028 0.0052 0.0261
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0043
Plasmodium vivax DNA repair protein REV1, putative 0.0019 0.0012 0.0732
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0116 0.0216
Echinococcus granulosus phosphoglycerate mutase 0.002 0.0019 0.0019
Brugia malayi Pre-SET motif family protein 0.0206 0.0855 0.3889
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0072 0.0133
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0012 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0199 0.0371
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0002 0.0002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.013 0.013
Plasmodium falciparum phosphoglucomutase-2 0.002 0.0019 0.1208
Leishmania major cathepsin L-like protease 0.0063 0.021 0.0392
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0023 0.0023
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0012 0.0022
Onchocerca volvulus Huntingtin homolog 0.0131 0.0516 0.0962
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0051 0.0158 0.0158
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0023 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.021 0.0392
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0116 0.0216
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0051 0.0158 0.0295
Loa Loa (eye worm) fibroinase 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.069 0.3036 0.5675
Onchocerca volvulus 0.0234 0.0982 0.1833
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0023 0.0023
Toxoplasma gondii phosphoglycerate mutase family protein 0.002 0.0019 0.0428
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0025 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0215 0.0215

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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