Detailed information for compound 1881144

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 304.467 | Formula: C20H32O2
  • H donors: 2 H acceptors: 2 LogP: 4.44 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=C[C@]1(C)CC[C@@]2([C@@H](C1)CC[C@@H]1C2=CC[C@@H](C1(C)C)O)CO
  • InChi: 1S/C20H32O2/c1-5-19(4)10-11-20(13-21)14(12-19)6-7-15-16(20)8-9-17(22)18(15,2)3/h5,8,14-15,17,21-22H,1,6-7,9-13H2,2-4H3/t14-,15-,17+,19-,20+/m1/s1
  • InChiKey: XHDDXJBGGUJQQL-XUMMFJMYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0291 0.0724 0.0714
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0421 0.041
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.0724 0.5849
Brugia malayi G-protein alpha subunit 0.002 0.0022 0.0037
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0016 0.0011 0.0018
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0056 0.0763
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.0227 0.0216
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0174 0.0421 0.041
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0039 0.0072 0.0061
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0135 0.0319 1
Schistosoma mansoni synaptojanin 0.0027 0.004 0.0029
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.002 0.0022 0.0011
Brugia malayi acetyltransferase, GNAT family protein 0.0172 0.0416 0.0694
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0157 0.0378 0.0768
Mycobacterium ulcerans polyketide synthase MbtD 0.0048 0.0095 0.1181
Schistosoma mansoni hypothetical protein 0.0174 0.042 0.041
Echinococcus granulosus jumonji domain containing protein 0.0043 0.008 0.0069
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0022 0.0011
Echinococcus granulosus neuropeptides capa receptor 0.0174 0.0421 0.041
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0097 0.0626
Brugia malayi Melatonin receptor type 1A 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0017 0.0532
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0291 0.0724 0.1208
Entamoeba histolytica hypothetical protein 0.0113 0.0262 0.8137
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.2323 0.5992 0.5987
Plasmodium falciparum DNase I-like protein, putative 0.0027 0.004 0.1255
Schistosoma mansoni hypothetical protein 0.008 0.0178 0.0168
Giardia lamblia Methyltransferase like 2 0.0047 0.0093 0.2337
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.002 0.0022 0.0037
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0027 0.004 0.0153
Onchocerca volvulus 0.0174 0.0421 0.3385
Treponema pallidum exodeoxyribonuclease (exoA) 0.0135 0.0319 1
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0027 0.004 0.041
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0104 0.0239 0.3205
Mycobacterium ulcerans polyketide synthase 0.0167 0.0403 0.5498
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0049 0.0535
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0023 0.003 0.0039
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0101 0.1263
Echinococcus multilocularis geminin 0.1218 0.3126 0.3118
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0016 0.0011 0.0018
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0421 0.041
Trypanosoma cruzi mitochondrial protein 99, putative 0.0027 0.004 0.041
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.004
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0022 0.0011
Leishmania major hypothetical protein, conserved 0.0047 0.0093 0.1145
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0033 0.0312
Schistosoma mansoni neutral sphingomyelinase 0.0027 0.004 0.0029
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0039 0.0072 0.0858
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0027 0.004 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0027 0.004 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0174 0.0421 0.041
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Echinococcus granulosus peregrin 0.0035 0.006 0.0049
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0027 0.004 0.0152
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0174 0.0421 0.041
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0027 0.004 0.0153
Schistosoma mansoni opsin-like receptor 0.0174 0.0421 0.041
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0034 0.1052
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Echinococcus granulosus neuropeptide Y receptor 0.0174 0.0421 0.041
Giardia lamblia PHD finger protein 15 0.0031 0.0049 0.086
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0027 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0039 0.0072 0.0858
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0421 0.041
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0029 0.0256
Brugia malayi Dopamine receptor protein 2 0.0174 0.0421 0.0702
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0027 0.004 0.0029
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0033 0.0312
Leishmania major RNA-editing complex protein MP100, putative 0.0027 0.004 0.041
Brugia malayi G protein-coupled receptor 0.0174 0.0421 0.0702
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Plasmodium vivax exodeoxyribonuclease III, putative 0.0027 0.004 0.0552
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Echinococcus multilocularis AMP dependent ligase 0.0017 0.0014 0.0003
Onchocerca volvulus 0.0291 0.0724 0.5887
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0468 0.1183 0.1173
Onchocerca volvulus 0.002 0.0022 0.009
Brugia malayi ORL1-like opioid receptor 0.0174 0.0421 0.0702
Schistosoma mansoni hypothetical protein 0.1218 0.3126 0.3118
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium ulcerans esterase/lipase LipP 0.0291 0.0724 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0054
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0022 0.0037
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0174 0.0421 0.0702
Echinococcus granulosus neuropeptide FF receptor 2 0.0174 0.0421 0.041
Echinococcus multilocularis neuropeptide FF receptor 2 0.0174 0.0421 0.041
Mycobacterium ulcerans hypothetical protein 0.0024 0.0033 0.0312
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Entamoeba histolytica hypothetical protein 0.0113 0.0262 0.8137
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.004 0.0552
Schistosoma mansoni biogenic amine receptor 0.0174 0.0421 0.041
Trichomonas vaginalis glutaminase, putative 0.0269 0.0668 0.5383
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0056
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0027 0.004 0.0153
Brugia malayi beta-lactamase 0.0291 0.0724 0.1208
Onchocerca volvulus Fatty acid synthase homolog 0.0284 0.0705 0.573
Toxoplasma gondii type I fatty acid synthase, putative 0.0168 0.0405 0.5534
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0174 0.0421 0.041
Brugia malayi Dopamine receptor protein 1 0.0174 0.0421 0.0702
Echinococcus multilocularis dro:myosuppressin receptor 0.0174 0.0421 0.041
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0056 0.0624
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0113 0.0262 0.0251
Brugia malayi Latrophilin receptor protein 2 0.008 0.0178 0.0298
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0033 0.0056
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0067
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0167 0.0403 0.0821
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0034 0.0463
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0033 0.0047
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0291 0.0724 0.1208
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0033 0.0312
Brugia malayi isocitrate dehydrogenase 0.0033 0.0056 0.0093
Schistosoma mansoni hypothetical protein 0.0302 0.0752 0.0742
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni neuropeptide f receptor 76f 0.0174 0.0421 0.041
Schistosoma mansoni biogenic amine receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0167 0.0403 0.0821
Brugia malayi glutaminase DH11.1 0.0269 0.0668 0.1115
Mycobacterium ulcerans thioesterase 0.0131 0.031 0.4189
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.004
Loa Loa (eye worm) melatonin receptor type 1A 0.0174 0.0421 0.0702
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0027 0.004 0.1255
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0028 0.0042 0.007
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0129 0.0118
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0174 0.0421 0.0702
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Trichomonas vaginalis set domain proteins, putative 0.0483 0.1222 1
Plasmodium vivax acyl carrier protein, putative 0.0016 0.0011 0.0148
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0039 0.0072 0.0858
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0122 0.0111
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0033 0.0047
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0049 0.0098 0.1219
Echinococcus granulosus neuropeptide s receptor 0.0174 0.0421 0.041
Leishmania major hypothetical protein, conserved 0.0027 0.004 0.041
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0023 0.003 0.0261
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.002 0.0022 0.0037
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0101 0.0659
Schistosoma mansoni ap endonuclease 0.0135 0.0319 0.0308
Echinococcus multilocularis synaptojanin 1 0.0027 0.004 0.0029
Echinococcus multilocularis traf and tnf receptor associated protein 0.0027 0.004 0.0029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0421 0.041
Entamoeba histolytica acyl-CoA synthetase, putative 0.004 0.0074 0.1996
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0022 0.0037
Onchocerca volvulus 0.0174 0.0421 0.3385
Onchocerca volvulus 0.0027 0.004 0.0241
Onchocerca volvulus 0.0174 0.0421 0.3385
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.107 0.1786
Onchocerca volvulus 0.0291 0.0724 0.5887
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0067
Schistosoma mansoni opsin-like receptor 0.0174 0.0421 0.041
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0468 0.1183 0.1173
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0049 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0468 0.1183 0.1173
Brugia malayi Serotonin receptor 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trypanosoma brucei polo-like protein kinase 0.0099 0.0227 0.3027
Mycobacterium tuberculosis Conserved protein 0.0291 0.0724 0.1492
Mycobacterium ulcerans polyketide synthase Pks13 0.0235 0.0579 0.7972
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi RE15519p 0.0174 0.0421 0.0702
Mycobacterium ulcerans beta-lactamase 0.0291 0.0724 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0129 0.0118
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0157 0.0378 0.5142
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0033 0.0312
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0022 0.0011
Schistosoma mansoni hypothetical protein 0.0031 0.0049 0.0038
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.009 0.225
Toxoplasma gondii type I fatty acid synthase, putative 0.0112 0.026 0.3494
Loa Loa (eye worm) G-protein coupled receptor 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0028 0.0043 0.0072
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni jumonji domain containing protein 0.008 0.0176 0.0165
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi UDP-GlcNAc:a-6-D-mannoside b1,2-N-acetylglucosaminyltransferase II 0.2323 0.5992 1
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0022 0.0011
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0227 0.6991
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0056 0.0045
Loa Loa (eye worm) hypothetical protein 0.2323 0.5992 1
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.002 0.0022 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0027 0.004 0.1255
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0027 0.004 0.041
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0113 0.0262 0.0251
Plasmodium falciparum importin beta, putative 0.0028 0.0043 0.1346
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0033 0.0312
Echinococcus multilocularis neuropeptides capa receptor 0.0174 0.0421 0.041
Echinococcus multilocularis serotonin receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trichomonas vaginalis penicillin-binding protein, putative 0.0291 0.0724 0.5849
Schistosoma mansoni carbon catabolite repressor protein 0.0027 0.004 0.0029
Mycobacterium tuberculosis Probable thioesterase TesA 0.0131 0.031 0.0625
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.002 0.0022 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0015 0.0008
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0027 0.004 0.0153
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0129 0.0118
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.004 0.041
Brugia malayi hypothetical protein 0.0113 0.0262 0.0437
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0298 0.0743 0.1239
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0129 0.0118
Mycobacterium ulcerans hypothetical protein 0.0027 0.004 0.041
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0174 0.0421 0.041
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0128 0.1635
Brugia malayi putative neuropeptide receptor NPR1 0.0174 0.0421 0.0702
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0056 0.0624
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0291 0.0724 1
Echinococcus multilocularis snurportin 1 0.0302 0.0752 0.0742
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0129 0.0303 0.0612
Echinococcus granulosus tm gpcr rhodopsin 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0265 0.0657 0.1097
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0033 0.0312
Mycobacterium ulcerans glutaminase 0.0269 0.0668 0.9214
Echinococcus granulosus tm gpcr rhodopsin 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0015 0.0008
Schistosoma mansoni cpg binding protein 0.0029 0.0044 0.0033
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0024 0.0013
Brugia malayi Methyltransferase-like protein 4 0.0047 0.0093 0.0155
Brugia malayi CXXC zinc finger family protein 0.0029 0.0044 0.0074
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0023 0.003 0.0039
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0152 0.0365 0.0741
Mycobacterium tuberculosis Conserved protein 0.0291 0.0724 0.1492
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0015 0.0008
Mycobacterium ulcerans Type I modular polyketide synthase 0.0157 0.0378 0.5142
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.004 0.0873
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0167 0.0403 0.0821
Echinococcus granulosus 7tm_1 domain containing protein 0.0174 0.0421 0.041
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0049 0.0038
Entamoeba histolytica G protein alpha subunit, putative 0.002 0.0022 0.0273
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0179
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0022 0.0011
Onchocerca volvulus 0.0174 0.0421 0.3385
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0093 0.0589
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0039 0.0072 0.0061
Brugia malayi Bromodomain containing protein 0.0035 0.006 0.01
Leishmania major endonuclease/exonuclease protein-like protein 0.0027 0.004 0.041
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0027 0.004 0.0873
Mycobacterium tuberculosis Conserved protein 0.0047 0.0093 0.0171
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0039 0.0072 0.0858
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0038 0.0069 0.0122
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0039 0.0072 1
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0027 0.004 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0024 0.0032 0.03
Brugia malayi follicle stimulating hormone receptor 0.0174 0.0421 0.0702
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.004 0.041
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0157 0.0378 0.0768
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0027 0.004 0.0061
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Onchocerca volvulus 0.0174 0.0421 0.3385
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0157 0.0378 0.5142
Loa Loa (eye worm) acyl carrier protein 0.0016 0.0011 0.0018
Loa Loa (eye worm) fatty acid synthase 0.0155 0.0372 0.0621
Trichomonas vaginalis ran, putative 0.0021 0.0024 0.0015
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0056 0.0045
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0017 0.0014 0.0036
Mycobacterium tuberculosis Conserved protein 0.0027 0.004 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0048 0.0095 0.0176
Onchocerca volvulus 0.0483 0.1222 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0033 0.0312
Onchocerca volvulus 0.0174 0.0421 0.3385
Brugia malayi beta-lactamase family protein 0.0291 0.0724 0.1208
Echinococcus granulosus tachykinin peptides receptor 99D 0.0174 0.0421 0.041
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0468 0.1183 0.1974
Entamoeba histolytica Ran family GTPase 0.0021 0.0024 0.0334
Loa Loa (eye worm) acyl carrier protein 0.0072 0.0157 0.0263
Onchocerca volvulus 0.0174 0.0421 0.3385
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Brugia malayi Dopamine receptor 0.0174 0.0421 0.0702
Echinococcus granulosus importin subunit beta 1 0.0028 0.0043 0.0032
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0167 0.0403 0.5498
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0174 0.0421 0.0702
Plasmodium falciparum acyl carrier protein 0.0016 0.0011 0.0337
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.002 0.0022 0.0037
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0235 0.0579 0.119
Echinococcus multilocularis peregrin 0.0035 0.006 0.0049
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0064 0.0135 0.0259
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0127 0.0298 0.4025
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Echinococcus multilocularis neuropeptide receptor 0.387 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.0724 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0167 0.0403 0.0393
Echinococcus granulosus synaptojanin 1 0.0027 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) G-protein coupled receptor 0.0174 0.0421 0.0702
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.008 0.0069
Echinococcus multilocularis neuropeptide s receptor 0.0174 0.0421 0.041
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Mycobacterium ulcerans thioesterase TesA 0.0131 0.031 0.4189
Schistosoma mansoni hypothetical protein 0.1218 0.3126 0.3118
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis fmrfamide receptor 0.0174 0.0421 0.041
Echinococcus multilocularis sex peptide receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0056
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0024 0.0013
Echinococcus granulosus traf and tnf receptor associated protein 0.0027 0.004 0.0029
Trypanosoma cruzi mitochondrial protein 99, putative 0.0027 0.004 0.041
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0135 0.0319 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis expressed protein 0.002 0.0022 0.0011
Brugia malayi PHD-finger family protein 0.0031 0.0049 0.0082
Brugia malayi beta-lactamase family protein 0.0291 0.0724 0.1208
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0468 0.1183 0.1173
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1859 0.4787 1
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0022 0.0011
Schistosoma mansoni glutaminase 0.0269 0.0668 0.0658
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.0629 0.105
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0027 0.004 0.0029
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0017 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0227 0.0216
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0174 0.0421 0.041
Echinococcus granulosus tm gpcr rhodopsin 0.0174 0.0421 0.041
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0157 0.0378 0.5142
Brugia malayi Serotonin receptor 0.0174 0.0421 0.0702
Toxoplasma gondii ABC1 family protein 0.0291 0.0724 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0129 0.1656
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0174 0.0421 0.041
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0029 0.0061
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.0724 0.5849
Schistosoma mansoni hypothetical protein 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0056 0.0624
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.004 0.0552
Echinococcus granulosus neuropeptide receptor 0.0174 0.0421 0.041
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.009 0.2508
Echinococcus granulosus neuropeptide receptor A26 0.0174 0.0421 0.041
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.0227 0.0378
Brugia malayi G-protein coupled receptor 0.0174 0.0421 0.0702
Brugia malayi hypothetical protein 0.002 0.0022 0.0037
Loa Loa (eye worm) TYRA-2 protein 0.0174 0.0421 0.0702
Schistosoma mansoni adenoreceptor 0.0174 0.0421 0.041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0033 0.0312
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Schistosoma mansoni alpha-1 adrenergic receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable lipase LipE 0.0291 0.0724 0.1492
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0033 0.0645
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0174 0.0421 0.041
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0291 0.0724 0.1492
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0023 0.003 0.0049
Mycobacterium ulcerans lipase LipD 0.0291 0.0724 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0129 0.0118
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0056 0.0093
Echinococcus multilocularis serotonin receptor 0.0174 0.0421 0.041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Schistosoma mansoni nocturnin 0.0027 0.004 0.0029
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.002 0.0022 0.0037
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0227 0.3027
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.002 0.0022 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0097 0.0626
Echinococcus granulosus G protein coupled receptor 139 0.0174 0.0421 0.041
Onchocerca volvulus 0.0023 0.003 0.0154
Loa Loa (eye worm) hypothetical protein 0.041 0.1033 0.1724
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0027 0.004 0.041
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0039 0.0072 0.2259
Mycobacterium tuberculosis Probable exported protein 0.0027 0.004 0.0061
Onchocerca volvulus 0.0174 0.0421 0.3385
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0028 0.0387
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0056
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.2323 0.5992 0.5987
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0027 0.004 0.0029
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0066 0.0055
Schistosoma mansoni trimeric G-protein alpha o subunit 0.002 0.0022 0.0011
Mycobacterium tuberculosis Probable hydrolase 0.0291 0.0724 0.1492
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0172 0.0416 0.0405
Echinococcus granulosus g protein coupled receptor 0.0174 0.0421 0.041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.004 0.041
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0135 0.0319 0.0308
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0033 0.0645
Schistosoma mansoni hypothetical protein 0.008 0.0178 0.0168
Onchocerca volvulus 0.0291 0.0724 0.5887
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0056 0.0624
Echinococcus multilocularis G protein coupled receptor 139 0.387 1 1
Brugia malayi hypothetical protein 0.0025 0.0034 0.0056
Brugia malayi exodeoxyribonuclease III family protein 0.0135 0.0319 0.0532
Loa Loa (eye worm) neuropeptide F receptor 0.0174 0.0421 0.0702
Entamoeba histolytica hypothetical protein 0.0023 0.0029 0.0514
Mycobacterium ulcerans polyketide synthase 0.0157 0.0378 0.5142
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Mycobacterium ulcerans Type I modular polyketide synthase 0.0157 0.0378 0.5142
Schistosoma mansoni histamine h1 receptor 0.0174 0.0421 0.041
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0134 0.0123
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0468 0.1183 0.1173
Loa Loa (eye worm) hypothetical protein 0.0031 0.0049 0.0082
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0023 0.003 0.0261
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0174 0.0421 0.041
Echinococcus granulosus AMP dependent ligase 0.0017 0.0014 0.0003
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trypanosoma brucei hypothetical protein, conserved 0.0236 0.0581 0.7998
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0285 0.0475
Onchocerca volvulus 0.0027 0.004 0.0241
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Schistosoma mansoni cript-related 0.0027 0.004 0.0029
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0027 0.004 0.0029
Brugia malayi neuropeptide F receptor 0.0174 0.0421 0.0702
Leishmania major hypothetical protein, conserved 0.0027 0.004 0.041
Onchocerca volvulus 0.0154 0.0369 0.296
Brugia malayi AMP-binding enzyme family protein 0.0154 0.0369 0.0617
Brugia malayi AKH receptor 0.0174 0.0421 0.0702
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.004 0.041
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0061
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0152 0.0365 0.0741
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0024 0.0041
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.041 0.1033 0.1724
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0028 0.0879
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0738
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0102 0.0234 0.3133
Onchocerca volvulus 0.0174 0.0421 0.3385
Echinococcus granulosus biogenic amine 5HT receptor 0.0174 0.0421 0.041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.007 0.0059
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0174 0.0421 0.041
Schistosoma mansoni cpg binding protein 0.003 0.0049 0.0038
Echinococcus multilocularis citrate lyase subunit beta protein 0.0027 0.004 0.0029
Leishmania major hypothetical protein, conserved 0.0027 0.004 0.041
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi MH2 domain containing protein 0.0121 0.0285 0.0475
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0179
Schistosoma mansoni synaptojanin 0.0027 0.004 0.0029
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0174 0.0421 0.041
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0135 0.0319 0.4314
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.002 0.0022 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0014 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Leishmania major hypothetical protein, conserved 0.0236 0.0581 0.7998
Toxoplasma gondii exonuclease III APE 0.0135 0.0319 0.4314
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus somatostatin receptor 0.0174 0.0421 0.041
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0056 0.1735
Brugia malayi G-protein coupled receptor 0.0174 0.0421 0.0702
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0049 0.0675
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0049 0.0038
Schistosoma mansoni opsin-like receptor 0.0174 0.0421 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0174 0.0421 0.041
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0034 0.0319
Brugia malayi RNA, U transporter 1 0.008 0.0178 0.0298
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.004 0.0153
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.0752 0.1256
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0127 0.0298 0.4025
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0027 0.004 0.041
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0049 0.0535
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus g protein coupled receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0127 0.0298 0.4025
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0056 0.0045
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0022 0.0011
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0027 0.004 0.1255
Mycobacterium leprae Probable polyketide synthase Pks1 0.0167 0.0403 0.5498
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.002 0.0022 0.0011
Onchocerca volvulus 0.002 0.0022 0.009
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0101 0.1392
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0024 0.0032 0.0045
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0135 0.0319 0.4314
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0178 0.0298
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.023 0.0219
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0174 0.0421 0.0702
Echinococcus multilocularis neuropeptide Y receptor 0.0174 0.0421 0.041
Plasmodium falciparum phd finger protein, putative 0.0031 0.0049 0.1535
Schistosoma mansoni hypothetical protein 0.0113 0.0262 0.0251
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.0227 0.3027
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0024 0.0032 0.0045
Entamoeba histolytica hypothetical protein 0.0113 0.0262 0.8137
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0174 0.0421 0.041
Schistosoma mansoni biogenic amine (5HT) receptor 0.0174 0.0421 0.041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0174 0.0421 0.041
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0131 0.031 0.4189
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0056 0.0045
Mycobacterium tuberculosis Probable esterase LipL 0.0291 0.0724 0.1492
Mycobacterium leprae Polyketide synthase Pks13 0.0235 0.0579 0.7972
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0023 0.003 0.0261
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0174 0.0421 0.041
Trichomonas vaginalis esterase, putative 0.0291 0.0724 0.5849
Echinococcus multilocularis beta LACTamase domain containing family member 0.0291 0.0724 0.0714
Trichomonas vaginalis ap endonuclease, putative 0.0135 0.0319 0.2472
Echinococcus granulosus neuropeptides capa receptor 0.0174 0.0421 0.041
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0027 0.004 0.041
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0033 0.0056
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.008 0.0178 0.0298
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Mycobacterium leprae conserved hypothetical protein 0.0291 0.0724 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.0724 1
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Brugia malayi GnHR receptor homolog 0.0174 0.0421 0.0702
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0056 0.0093
Onchocerca volvulus Neuropeptide F receptor homolog 0.0174 0.0421 0.3385
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0022 0.0011
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.002 0.0022 0.0037
Brugia malayi putative neuropeptide receptor 0.0174 0.0421 0.0702
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0178 0.0168
Onchocerca volvulus 0.0281 0.0698 0.5675
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0154 0.0369 0.0617
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0135 0.0319 1
Trypanosoma brucei RNA editing exonuclease 2 0.0027 0.004 0.041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0135 0.0319 0.4314
Echinococcus granulosus guanine nucleotide binding protein G protein 0.002 0.0022 0.0011
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.0227 0.1782
Treponema pallidum hypothetical protein 0.0027 0.004 0.095
Mycobacterium tuberculosis Probable lipase LipD 0.0291 0.0724 0.1492
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0056
Schistosoma mansoni neuropeptide receptor 0.0174 0.0421 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0039 0.0072 0.0061
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0174 0.0421 0.041
Giardia lamblia Kinase, PLK 0.0099 0.0227 0.6887
Trichomonas vaginalis penicillin-binding protein, putative 0.0291 0.0724 0.5849
Echinococcus granulosus alpha 1A adrenergic receptor 0.0174 0.0421 0.041
Brugia malayi jmjC domain containing protein 0.01 0.023 0.0383
Loa Loa (eye worm) G protein alpha subunit 3 0.002 0.0022 0.0037
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0179
Echinococcus multilocularis cpg binding protein 0.003 0.0049 0.0038
Schistosoma mansoni hypothetical protein 0.0174 0.0421 0.041
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0027 0.004 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0027 0.004 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0172 0.0416 0.0405
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0027 0.004 0.0873
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0291 0.0724 0.0714
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0033 0.0312
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Onchocerca volvulus 0.0061 0.0129 0.0975
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0022 0.0011
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0027 0.004 0.0153
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0056 0.0045
Echinococcus granulosus neuropeptide Y receptor 0.0174 0.0421 0.041
Brugia malayi hypothetical protein 0.0016 0.0011 0.0019
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.002 0.0022 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0291 0.0724 0.1492
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0033 0.0056
Onchocerca volvulus 0.0024 0.0033 0.0184
Brugia malayi Pre-SET motif family protein 0.0424 0.107 0.1786
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0174 0.0421 0.041
Onchocerca volvulus 0.0174 0.0421 0.3385
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0027 0.004 0.041
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.002 0.0022 0.0037
Echinococcus granulosus allatostatin A receptor 0.0174 0.0421 0.041
Schistosoma mansoni GTP-binding protein alpha subunit 0.002 0.0022 0.0011
Brugia malayi Importin beta-1 subunit 0.0028 0.0043 0.0072
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.0227 0.0216
Schistosoma mansoni myosin xvIII 0.0174 0.0421 0.041
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0174 0.0421 0.041
Plasmodium vivax importin-beta 2, putative 0.0028 0.0043 0.0592
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0174 0.0421 0.041
Mycobacterium tuberculosis Hypothetical protein 0.0047 0.0093 0.0171
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.002 0.0022 0.0037
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0056 0.0093
Echinococcus granulosus cpg binding protein 0.003 0.0049 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0468 0.1183 0.1173
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi Phosphopantetheine attachment site family protein 0.0016 0.0011 0.0018
Schistosoma mansoni importin beta-1 0.0028 0.0043 0.0032
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.004 0.041
Mycobacterium ulcerans polyketide synthase MbtC 0.0039 0.0072 0.0858
Echinococcus multilocularis g protein coupled receptor 0.0174 0.0421 0.041
Leishmania major importin beta-1 subunit, putative 0.0023 0.0029 0.0256
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0023 0.003 0.0039
Leishmania major hypothetical protein, conserved 0.0291 0.0724 1
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi sulfakinin receptor protein 0.0174 0.0421 0.0702
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0157 0.0378 0.063
Echinococcus granulosus citrate lyase subunit beta protein 0.0027 0.004 0.0029
Onchocerca volvulus 0.0174 0.0421 0.3385
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0034 0.1052
Schistosoma mansoni hypothetical protein 0.0174 0.0421 0.041
Schistosoma mansoni neuropeptide F-like receptor 0.0174 0.0421 0.041
Schistosoma mansoni transcription factor LCR-F1 0.0113 0.0262 0.0251
Mycobacterium ulcerans fatty acid synthase Fas 0.0049 0.0098 0.1219
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi larval opioid receptor 0.0174 0.0421 0.0702
Mycobacterium ulcerans Type I modular polyketide synthase 0.0157 0.0378 0.5142
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0027 0.004 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0061
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0056 0.0045
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0044 0.0074
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0027 0.004 0.1255
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1646 0.4237 0.4231
Echinococcus multilocularis somatostatin receptor 0.0174 0.0421 0.041
Echinococcus multilocularis g-protein coupled receptor 0.0174 0.0421 0.041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0104 0.0239 0.3205
Schistosoma mansoni ran 0.0021 0.0024 0.0013
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0039 0.0072 0.0858
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0135 0.0319 0.4314
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.002 0.0022 0.0037
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.004 0.0873
Onchocerca volvulus 0.0174 0.0421 0.3385
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0023 0.003 0.0261
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0027 0.004 0.041
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.0227 0.0378
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0056 0.0624
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0174 0.0421 0.0702
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0285 0.0475
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0023 0.003 0.0261
Echinococcus granulosus geminin 0.1218 0.3126 0.3118
Echinococcus granulosus neutral sphingomyelinase 0.0027 0.004 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0129 0.0118
Schistosoma mansoni neuropeptide receptor 0.0174 0.0421 0.041
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0034 0.0319
Schistosoma mansoni kinase 0.005 0.01 0.009
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0028 0.0042 0.0166
Echinococcus multilocularis neuropeptides capa receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0089 0.0202 0.0399
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0135 0.0319 0.0308
Loa Loa (eye worm) hypothetical protein 0.0088 0.0198 0.0331
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0033 0.0312
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0015 0.0008
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0157 0.0378 0.0768
Echinococcus granulosus GPCR family 2 0.008 0.0178 0.0168
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Schistosoma mansoni biogenic amine receptor 0.0174 0.0421 0.041
Trypanosoma cruzi hypothetical protein, conserved 0.0236 0.0581 0.7998
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0033 0.0312
Brugia malayi G protein-coupled receptor F59B2.13 0.0174 0.0421 0.0702
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0174 0.0421 0.0702
Loa Loa (eye worm) glutaminase 0.0269 0.0668 0.1115
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0135 0.0319 0.4399
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.002 0.0022 0.0037
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0028 0.0043 0.0446
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0039 0.0072 0.012
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0236 0.0583 0.0572
Entamoeba histolytica hypothetical protein 0.0113 0.0262 0.8137
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0056 0.0624
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0101 0.0659
Leishmania major GTP-binding protein, putative 0.0021 0.0024 0.0179
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0081 0.0178 0.2349
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0039 0.0072 0.012
Schistosoma mansoni hypothetical protein 0.008 0.0178 0.0168
Echinococcus granulosus snurportin 1 0.0302 0.0752 0.0742
Schistosoma mansoni neuropeptide receptor 0.387 1 1
Echinococcus multilocularis allatostatin A receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0174 0.0421 0.0702
Leishmania major hypothetical protein, conserved 0.0025 0.0034 0.0319
Onchocerca volvulus Putative neutral sphingomyelinase 0.0027 0.004 0.0241
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0291 0.0724 0.1492
Echinococcus granulosus beta LACTamase domain containing family member 0.0291 0.0724 0.0714
Onchocerca volvulus 0.0174 0.0421 0.3385
Mycobacterium tuberculosis Conserved protein 0.0291 0.0724 0.1492
Onchocerca volvulus 0.0174 0.0421 0.3385
Echinococcus multilocularis G-protein coupled receptor, putative 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis neutral sphingomyelinase 0.0027 0.004 0.0029
Echinococcus granulosus dro:myosuppressin receptor 0.0174 0.0421 0.041
Brugia malayi Pre-SET motif family protein 0.0061 0.0129 0.0215
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0024 0.0179
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0235 0.0579 0.119
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.004 0.0067
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0043 0.0032
Trichomonas vaginalis Phospholipase C precursor, putative 0.0027 0.004 0.0153
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0174 0.0421 0.041
Schistosoma mansoni growth hormone secretagogue receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0291 0.0724 0.1208
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Loa Loa (eye worm) beta-lactamase 0.0291 0.0724 0.1208
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0024 0.0032 0.0045
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0167 0.0403 0.5498
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0037
Trypanosoma brucei hypothetical protein, conserved 0.0291 0.0724 1
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.004 0.0153
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0056 0.0045
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0129 0.0118
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0067
Echinococcus granulosus peptide allatostatin:somatostatin 0.0174 0.0421 0.041
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.009 0.2822
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0113 0.0263 0.0527
Echinococcus granulosus rhodopsin orphan GPCR 0.0174 0.0421 0.041
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0174 0.0421 0.041
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Echinococcus granulosus guanine nucleotide binding protein subunit 0.002 0.0022 0.0011
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Echinococcus multilocularis deoxyribonuclease 1 2 0.0027 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0174 0.042 0.0702
Loa Loa (eye worm) hypothetical protein 0.0052 0.0106 0.0177
Schistosoma mansoni ran 0.0021 0.0024 0.0013
Mycobacterium leprae Probable lipase LipE 0.0291 0.0724 1
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0039 0.0072 0.1989
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0043 0.0451
Brugia malayi CCR4 0.0028 0.0042 0.007
Schistosoma mansoni hypothetical protein 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0039 0.0072 0.0993
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.2323 0.5992 0.5987
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0174 0.0421 0.0702
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0027 0.004 0.0029
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0054
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0135 0.0319 0.0644
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0039 0.0072 0.0858
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0022 0.0011
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.007 0.0059
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.0629 0.105
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0027 0.004 0.0873
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0135 0.0319 0.4314
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.004 0.0067
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0154 0.0369 0.075
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.003 0.0261
Toxoplasma gondii type I fatty acid synthase 0.0024 0.0032 0.03
Brugia malayi jmjC domain containing protein 0.0039 0.007 0.0117
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0054 0.011 0.0207
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.023 0.0219
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0236 0.0583 0.0572
Schistosoma mansoni biogenic amine (5HT) receptor 0.0174 0.0421 0.041
Trichomonas vaginalis ap endonuclease, putative 0.0135 0.0319 0.2472
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0167 0.0403 0.5498
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0167 0.0403 0.5498
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0468 0.1183 0.1974
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0101 0.1263
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0227 0.1707
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.002 0.0022 0.0011
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.041
Brugia malayi Tachykinin-like peptides receptor 99D 0.0174 0.0421 0.0702
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.002 0.0022 0.0011
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0049 0.0038
Echinococcus granulosus fmrfamide receptor 0.0174 0.0421 0.041
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0061 0.0129 0.0215
Onchocerca volvulus 0.0174 0.0421 0.3385
Echinococcus multilocularis GPCR, family 2 0.008 0.0178 0.0168
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0014 0.0036
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0178 0.0298
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.002 0.0009
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0033 0.0312
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0034 0.0319
Schistosoma mansoni ap endonuclease 0.0135 0.0319 0.0308
Onchocerca volvulus 0.0029 0.0044 0.0275
Giardia lamblia Inositol 5-phosphatase 4 0.0027 0.004 0.0558
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0017 0.0014 0.0036
Schistosoma mansoni amine GPCR 0.0174 0.0421 0.041
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.007 0.0117
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0024 0.0325
Schistosoma mansoni methyltransferase-related 0.0047 0.0093 0.0082
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0174 0.0421 0.041
Mycobacterium ulcerans polyketide synthase Pks9 0.0104 0.0239 0.3205
Onchocerca volvulus 0.002 0.0022 0.009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0468 0.1183 0.1173
Loa Loa (eye worm) acetyltransferase 0.0172 0.0416 0.0694
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0178 0.0168
Schistosoma mansoni neuropeptide receptor 0.0174 0.0421 0.041
Trypanosoma cruzi hypothetical protein, conserved 0.0236 0.0581 0.7998
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0034 0.0319
Echinococcus multilocularis orexin receptor type 2 0.0174 0.0421 0.041
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0043 0.0451
Echinococcus granulosus 7TM GPCR rhodopsin 0.0174 0.0421 0.041
Plasmodium vivax hypothetical protein, conserved 0.0027 0.004 0.0552
Echinococcus multilocularis neuropeptide receptor 0.0174 0.0421 0.041
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0174 0.0421 0.0702
Mycobacterium ulcerans hypothetical protein 0.0291 0.0724 1
Schistosoma mansoni hypothetical protein 0.008 0.0178 0.0168
Echinococcus granulosus hypothetical protein 0.0174 0.0421 0.041
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0174 0.0421 0.3385
Loa Loa (eye worm) hypothetical protein 0.0018 0.0017 0.0029
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0017 0.1017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0023 0.003 0.0039
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.002 0.0022 0.0011
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0174 0.0421 0.041
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0027 0.004 0.041
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0134 0.0223
Brugia malayi hypothetical protein 0.0174 0.0421 0.0702
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0098 0.0163
Leishmania major pantothenate kinase subunit, putative 0.0028 0.0043 0.0446
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0101 0.009
Brugia malayi neuropeptide F receptor 0.0174 0.0421 0.0702
Echinococcus multilocularis neuropeptide Y receptor 0.0174 0.0421 0.041
Schistosoma mansoni hypothetical protein 0.0027 0.004 0.0029
Echinococcus granulosus expressed protein 0.002 0.0022 0.0011
Loa Loa (eye worm) neuropeptide F receptor 0.0174 0.0421 0.0702
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0227 0.3027
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.042 0.0702
Loa Loa (eye worm) glutaminase 2 0.0269 0.0668 0.1115
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.004 0.041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.007 0.0059
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.002 0.0022 0.0037
Trichomonas vaginalis D-aminoacylase, putative 0.0291 0.0724 0.5849
Giardia lamblia hypothetical protein 0.0027 0.004 0.0558
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0056 0.0624
Schistosoma mansoni cpg binding protein 0.003 0.0049 0.0038
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0017 0.0013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0135 0.0319 0.0532
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Mycobacterium ulcerans hypothetical protein 0.0027 0.004 0.041
Schistosoma mansoni neuropeptide F-like receptor 0.0174 0.0421 0.041
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0135 0.0319 1
Echinococcus granulosus g protein coupled receptor 0.0174 0.0421 0.041
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0017 0.0234
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0039 0.0072 0.0858
Echinococcus granulosus biogenic amine 5HT receptor 0.0174 0.0421 0.041
Echinococcus granulosus g-protein coupled receptor 0.0174 0.0421 0.041
Echinococcus multilocularis fmrfamide receptor 0.0174 0.0421 0.041
Onchocerca volvulus Alhambra homolog 0.0031 0.0049 0.0315
Plasmodium vivax hypothetical protein, conserved 0.0291 0.0724 1
Echinococcus granulosus sex peptide receptor 0.0174 0.0421 0.041
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0043 0.0451
Echinococcus granulosus orexin receptor type 2 0.0174 0.0421 0.041
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.004 0.0873
Loa Loa (eye worm) hypothetical protein 0.0027 0.004 0.0067
Plasmodium vivax SET domain protein, putative 0.0061 0.0129 0.1779
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis neuropeptide receptor A26 0.0174 0.0421 0.041
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0049 0.0098 0.0182
Loa Loa (eye worm) hypothetical protein 0.0174 0.0421 0.0702
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0174 0.0421 0.041
Echinococcus granulosus serotonin receptor 0.0174 0.0421 0.041
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0024 0.0032 0.0045

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 5.57 uM Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method ChEMBL. 24660966

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 24660966

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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