Detailed information for compound 1906279

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 292.335 | Formula: C17H16N4O
  • H donors: 2 H acceptors: 2 LogP: 3.01 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1ccc(cc1)/C=N/NC(=O)Nc1c(C)cccc1C
  • InChi: 1S/C17H16N4O/c1-12-4-3-5-13(2)16(12)20-17(22)21-19-11-15-8-6-14(10-18)7-9-15/h3-9,11H,1-2H3,(H2,20,21,22)/b19-11+
  • InChiKey: PKMXDJNFSCMMCI-YBFXNURJSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bacillus anthracis Antrax lethal toxin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0063 0.0153 0.0601
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0182 0.0493 0.1933
Onchocerca volvulus 0.0886 0.251 1
Echinococcus granulosus tar DNA binding protein 0.0097 0.025 0.0941
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0182 0.0493 0.196
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0063 0.0153 0.0605
Echinococcus multilocularis caspase 8 0.0026 0.0048 0.0182
Giardia lamblia Pms1-like protein 0.001 0.0002 0.0014
Trypanosoma cruzi metacaspase, putative 0.0026 0.0048 0.0181
Trypanosoma cruzi heat shock protein 85, putative 0.0059 0.0141 0.054
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0177
Loa Loa (eye worm) hypothetical protein 0.0286 0.0791 0.31
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0025 0.0045 0.017
Echinococcus multilocularis heat shock protein 90 0.0069 0.017 0.0639
Onchocerca volvulus 0.0049 0.0113 0.0452
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0493 0.196
Leishmania major cathepsin L-like protease 0.0886 0.251 0.9691
Brugia malayi Papain family cysteine protease containing protein 0.0467 0.1311 0.5139
Loa Loa (eye worm) jmjC domain-containing protein 0.0088 0.0226 0.0885
Trypanosoma cruzi prolyl endopeptidase 0.0079 0.0199 0.0761
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Brugia malayi glutaminase DH11.1 0.0283 0.0782 0.3066
Trichomonas vaginalis rotamase, putative 0.0101 0.0262 0.104
Onchocerca volvulus Cathepsin L homolog 0.0886 0.251 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0286 0.0791 0.31
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0043 0.0374
Giardia lamblia Cathepsin B precursor 0.0404 0.1129 1
Brugia malayi Trypsin family protein 0.0025 0.0045 0.0177
Brugia malayi hypothetical protein 0.0024 0.0043 0.0169
Schistosoma mansoni integrin beta subunit 0.01 0.0259 0.0976
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0023 0.004 0.0149
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Brugia malayi cathepsin L-like precursor 0.0601 0.1692 0.6635
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0025 0.0044 0.0171
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0012 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.004 0.0156
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0026 0.0047 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.0262 0.104
Brugia malayi putative neuropeptide receptor 0.0049 0.0113 0.0445
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0113 0.0445
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.004 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Loa Loa (eye worm) TOPoisomerase family member 0.001 0.0002 0.0006
Plasmodium falciparum metacaspase 1 0.0026 0.0048 0.0187
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0056 0.0133 0.051
Brugia malayi jmjC domain containing protein 0.0088 0.0226 0.0885
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0062 0.0235
Toxoplasma gondii Hsp90 domain-containing protein 0.0261 0.0719 0.2864
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0046 0.0104 0.0391
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0097 0.025 0.098
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0107 0.0279 0.1051
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0113 0.0427
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0113 0.0427
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0023 0.004 0.0149
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0046 0.0104 0.0408
Schistosoma mansoni tar DNA-binding protein 0.0097 0.025 0.0941
Brugia malayi RNA binding protein 0.0097 0.025 0.098
Giardia lamblia Cathepsin L precursor 0.0182 0.0493 0.4366
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0493 0.196
Leishmania major heat shock protein, putative 0.0046 0.0104 0.0395
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Plasmodium vivax serine-repeat antigen (SERA) 0.0182 0.0493 0.196
Brugia malayi Papain family cysteine protease containing protein 0.0467 0.1311 0.5139
Onchocerca volvulus Alhambra homolog 0.0022 0.0036 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0493 0.196
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0026 0.0215
Echinococcus granulosus cathepsin l1 0.0601 0.1692 0.6368
Onchocerca volvulus 0.0245 0.0675 0.269
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0113 0.0427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Trypanosoma cruzi cysteine peptidase, putative 0.0914 0.259 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.007 0.0172 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0187
Trypanosoma brucei C-terminal motor kinesin, putative 0.0075 0.0188 0.0724
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0113 0.0427
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0182 0.0493 0.196
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0182 0.0493 0.1856
Plasmodium falciparum cysteine proteinase falcipain 3 0.0886 0.251 1
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0056 0.0133 0.0522
Trypanosoma cruzi heat shock protein 85, putative 0.0069 0.017 0.065
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0113 0.0427
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Giardia lamblia Heat shock protein HSP 90-alpha 0.0059 0.0141 0.1252
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Trichomonas vaginalis heat shock protein, putative 0.0069 0.017 0.0671
Toxoplasma gondii DNA topoisomerase 2, putative 0.001 0.0002 0.0006
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Onchocerca volvulus 0.0049 0.0113 0.0452
Trypanosoma brucei metacaspase MCA3 0.0026 0.0048 0.0184
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0043 0.017
Onchocerca volvulus 0.0017 0.0022 0.0087
Trypanosoma cruzi heat shock protein, putative 0.0046 0.0104 0.0395
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0113 0.0427
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0113 0.0427
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0901 0.255 0.9599
Echinococcus granulosus Mastin 0.0025 0.0045 0.017
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Echinococcus multilocularis tar DNA binding protein 0.0097 0.025 0.0941
Schistosoma mansoni hypothetical protein 0.0025 0.0045 0.017
Trypanosoma cruzi major cysteine proteinase, putative 0.0182 0.0493 0.1899
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0031 0.0063 0.0183
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0113 0.0427
Echinococcus granulosus cathepsin b 0.0901 0.255 0.9599
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0038 0.0083 0.0325
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0113 0.0445
Onchocerca volvulus 0.0025 0.0045 0.018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0886 0.251 0.984
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Onchocerca volvulus 0.0049 0.0113 0.0452
Loa Loa (eye worm) RNA binding protein 0.0097 0.025 0.098
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0113 0.0427
Trypanosoma brucei DNA topoisomerase ii 0.001 0.0002 0.0003
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0113 0.0427
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0113 0.0452
Schistosoma mansoni hypothetical protein 0.0049 0.0113 0.0427
Brugia malayi Cathepsin L-like precursor 0.0886 0.251 0.984
Brugia malayi AKH receptor 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Schistosoma mansoni endoplasmin 0.0069 0.017 0.0639
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0048 0.019
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Toxoplasma gondii cathepsin CPC1 0.0182 0.0493 0.1965
Entamoeba histolytica hypothetical protein 0.0182 0.0493 0.196
Echinococcus granulosus glycoprotein Antigen 5 0.0025 0.0045 0.017
Loa Loa (eye worm) isocitrate dehydrogenase 0.0012 0.0008 0.0032
Schistosoma mansoni hypothetical protein 0.0024 0.0043 0.0163
Trypanosoma cruzi cysteine protease, putative 0.0467 0.1311 0.5058
Schistosoma mansoni hypothetical protein 0.0058 0.0139 0.0524
Echinococcus granulosus proteasome prosome macropain 0.0056 0.0133 0.0499
Echinococcus granulosus cathepsin l1 0.0886 0.251 0.9445
Brugia malayi Papain family cysteine protease containing protein 0.0182 0.0493 0.1933
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0063 0.0153 0.0601
Trypanosoma cruzi cysteine peptidase, putative 0.0914 0.259 1
Plasmodium falciparum serine repeat antigen 5 0.0182 0.0493 0.196
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0113 0.0427
Toxoplasma gondii cathepsin B 0.0404 0.1129 0.45
Brugia malayi Dopamine receptor protein 2 0.0049 0.0113 0.0445
Brugia malayi Trypsin family protein 0.0025 0.0045 0.0177
Schistosoma mansoni jumonji domain containing protein 0.0023 0.004 0.0149
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus granulosus SHC transforming protein 3 0.0053 0.0124 0.0467
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0056 0.0133 0.0522
Echinococcus multilocularis cathepsin L 0.0182 0.0493 0.1856
Trypanosoma brucei Metacaspase-4 0.0026 0.0048 0.0184
Onchocerca volvulus 0.0886 0.251 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Trypanosoma brucei heat shock protein 90, putative 0.0069 0.017 0.0653
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0177
Echinococcus multilocularis caspase 0.007 0.0172 0.0647
Schistosoma mansoni hypothetical protein 0.0025 0.0045 0.017
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0048 0.0193
Brugia malayi Trypsin family protein 0.0257 0.0707 0.2774
Echinococcus granulosus prolyl endopeptidase 0.0079 0.0199 0.0747
Mycobacterium ulcerans replicative DNA helicase DnaB 0.04 0.1116 1
Giardia lamblia Cathepsin B precursor 0.0182 0.0493 0.4366
Schistosoma mansoni amine GPCR 0.0049 0.0113 0.0427
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0013 0.0049
Entamoeba histolytica cysteine proteinase, putative 0.0467 0.1311 0.5219
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0045 0.017
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0056 0.0133 0.0499
Schistosoma mansoni hypothetical protein 0.0049 0.0113 0.0427
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0012 0.0008 0.0027
Echinococcus multilocularis serotonin receptor 0.0049 0.0113 0.0427
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0182 0.0493 0.4366
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.001 0.0002 0.0006
Brugia malayi Papain family cysteine protease containing protein 0.0182 0.0493 0.1933
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.01
Schistosoma mansoni myosin xvIII 0.0049 0.0113 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0182 0.0493 0.196
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0014 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Trypanosoma cruzi DNA polymerase kappa, putative 0.0014 0.0013 0.0044
Echinococcus granulosus g protein coupled receptor 0.0049 0.0113 0.0427
Trypanosoma cruzi cysteine peptidase, putative 0.0467 0.1311 0.5058
Echinococcus granulosus endoplasmin 0.0065 0.0158 0.0594
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.001 0.0002 0.0006
Plasmodium falciparum phd finger protein, putative 0.0022 0.0036 0.0136
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0063 0.0153 0.0611
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Onchocerca volvulus 0.0025 0.0043 0.0172
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0113 0.0427
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.0008 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Entamoeba histolytica kinesin, putative 0.0075 0.0188 0.0744
Echinococcus multilocularis endoplasmin 0.0065 0.0158 0.0594
Loa Loa (eye worm) transcription factor SMAD2 0.0089 0.0227 0.089
Echinococcus multilocularis cathepsin b 0.0901 0.255 0.9599
Brugia malayi Trypsin-like protease protein 5 0.0025 0.0045 0.0177
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0182 0.0493 0.4366
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0257 0.0707 0.2662
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0042 0.016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0886 0.251 0.9445
Echinococcus multilocularis cathepsin L 0.0467 0.1311 0.4932
Loa Loa (eye worm) ctsf protein 0.0886 0.251 0.984
Brugia malayi Cathepsin L-like precursor 0.0886 0.251 0.984
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.001 0.0002 0.0006
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0031 0.0063 0.0061
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0034 0.0071 0.0273
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0051
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0061 0.023
Loa Loa (eye worm) hypothetical protein 0.0257 0.0707 0.2774
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0158 0.0623
Entamoeba histolytica cysteine protease, putative 0.0886 0.251 1
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0065 0.0158 0.0156
Echinococcus multilocularis Mastin 0.0025 0.0045 0.017
Brugia malayi jmjC domain containing protein 0.0023 0.004 0.0156
Trypanosoma brucei heat shock protein, putative 0.0069 0.017 0.0653
Echinococcus multilocularis expressed protein 0.0101 0.0262 0.0988
Echinococcus granulosus cathepsin L 0.0467 0.1311 0.4932
Echinococcus multilocularis lysine specific demethylase 5A 0.0087 0.0223 0.0839
Onchocerca volvulus 0.0049 0.0113 0.0452
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0113 0.0427
Brugia malayi Protein kinase domain containing protein 0.0032 0.0066 0.0259
Schistosoma mansoni histamine h1 receptor 0.0049 0.0113 0.0427
Mycobacterium ulcerans hypothetical protein 0.0025 0.0043 0.0374
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0404 0.1129 0.4497
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0046 0.0104 0.0391
Trichomonas vaginalis heat shock protein, putative 0.004 0.0087 0.0343
Toxoplasma gondii peptidylprolyl isomerase 0.0099 0.0256 0.1019
Brugia malayi Kringle domain containing protein 0.0032 0.0066 0.0259
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0886 0.251 1
Schistosoma mansoni cathepsin F (C01 family) 0.0886 0.251 0.9445
Plasmodium falciparum heat shock protein 90, putative 0.0261 0.0719 0.2859
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0023 0.0021
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0182 0.0493 0.196
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0079 0.0199 0.0761
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0031 0.0063 0.0237
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0171
Brugia malayi Dopamine receptor protein 1 0.0049 0.0113 0.0445
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0048 0.0184
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0187
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0257 0.0707 0.2662
Plasmodium vivax unspecified product 0.0182 0.0493 0.196
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0025 0.0045 0.017
Echinococcus multilocularis jumonji domain containing 1A 0.0023 0.004 0.0149
Onchocerca volvulus 0.0025 0.0045 0.018
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0025 0.0045 0.0177
Trichomonas vaginalis glutaminase, putative 0.0283 0.0782 0.3111
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0886 0.251 0.984
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Toxoplasma gondii cathepsin CPL 0.0886 0.251 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0045 0.017
Trypanosoma cruzi heat shock protein 90, putative 0.0059 0.0141 0.054
Plasmodium vivax metacaspase 1, putative 0.0026 0.0048 0.0187
Echinococcus multilocularis laminin 0.0025 0.0044 0.0164
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0113 0.0427
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.0008 0.0031
Brugia malayi cathepsin Z-like cysteine proteinase 0.0182 0.0493 0.1933
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Onchocerca volvulus 0.0025 0.0045 0.018
Loa Loa (eye worm) cathepsin B 0.0404 0.1129 0.4428
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Toxoplasma gondii TIM10 family protein, putative 0.0038 0.0083 0.033
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0901 0.255 0.9599
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0182 0.0493 0.4366
Onchocerca volvulus 0.0049 0.0113 0.0452
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0043 0.0161
Echinococcus multilocularis PHD finger protein rhinoceros 0.0022 0.0036 0.0134
Onchocerca volvulus 0.0231 0.0635 0.2531
Schistosoma mansoni jumonji domain containing protein 0.0118 0.031 0.1167
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus multilocularis cathepsin L cysteine protease 0.0886 0.251 0.9445
Plasmodium falciparum serine repeat antigen 3 0.0182 0.0493 0.196
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0031 0.0061 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0043 0.0166
Loa Loa (eye worm) hypothetical protein 0.0025 0.0043 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0187
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.04 0.1116 1
Entamoeba histolytica cysteine protease, putative 0.0182 0.0493 0.196
Schistosoma mansoni glutaminase 0.0283 0.0782 0.2943
Schistosoma mansoni tar DNA-binding protein 0.0097 0.025 0.0941
Leishmania major DNA polymerase eta, putative 0.0014 0.0013 0.0044
Plasmodium falciparum LCCL domain-containing protein 0.0017 0.0023 0.0086
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Loa Loa (eye worm) hypothetical protein 0.0182 0.0493 0.1933
Trypanosoma brucei heat shock protein, putative 0.0069 0.017 0.0653
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0026 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0187
Brugia malayi Dopamine receptor 0.0049 0.0113 0.0445
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.0008 0.0031
Echinococcus multilocularis heat shock protein 90 0.0059 0.0141 0.0532
Toxoplasma gondii kringle domain-containing protein 0.0032 0.0066 0.0263
Leishmania major oligopeptidase b 0.0031 0.0063 0.0237
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0113 0.0427
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0023 0.0021
Schistosoma mansoni caspase-7 (C14 family) 0.007 0.0172 0.0647
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0177
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0065 0.0158 0.0467
Loa Loa (eye worm) hypothetical protein 0.0065 0.016 0.0629
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0113 0.0427
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0058 0.0219
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0182 0.0493 0.1856
Giardia lamblia Cathepsin L-like protease 0.0182 0.0493 0.4366
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0182 0.0493 0.196
Mycobacterium ulcerans recombinase A 0.0112 0.0292 0.2609
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Echinococcus multilocularis lysine specific demethylase 6a 0.0023 0.004 0.0149
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0171
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0043 0.0161
Schistosoma mansoni amine GPCR 0.0049 0.0113 0.0427
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0113 0.0427
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0012 0.0008 0.0029
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0038 0.0083 0.0312
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0259
Trypanosoma brucei metacaspase MCA2 0.0026 0.0048 0.0184
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0113 0.0427
Onchocerca volvulus 0.0049 0.0113 0.0452
Trypanosoma brucei DNA topoisomerase II beta, putative 0.001 0.0002 0.0003
Trypanosoma cruzi heat shock protein 90, putative 0.0069 0.017 0.065
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0113 0.0427
Echinococcus multilocularis dna polymerase eta 0.0014 0.0013 0.0049
Trypanosoma cruzi cysteine proteinase, putative 0.0467 0.1311 0.5058
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0042 0.016
Plasmodium vivax vivapain-1 0.0467 0.1311 0.5219
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0038 0.0083 0.0325
Brugia malayi Fibulin-1 precursor 0.0025 0.0044 0.0171
Schistosoma mansoni hypothetical protein 0.0058 0.0139 0.0524
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Leishmania major C-terminal motor kinesin, putative 0.0075 0.0188 0.0721
Loa Loa (eye worm) hypothetical protein 0.0286 0.0791 0.31
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0182 0.0493 0.1856
Trypanosoma brucei heat shock protein, putative 0.0069 0.017 0.0653
Entamoeba histolytica hypothetical protein 0.0107 0.0279 0.1107
Loa Loa (eye worm) MH2 domain-containing protein 0.0089 0.0227 0.089
Mycobacterium ulcerans DNA polymerase IV 0.0014 0.0013 0.0103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Echinococcus granulosus neurogenic locus notch protein 0.0009 0.0000000036994 0.000000013922
Echinococcus granulosus lysine specific demethylase 5A 0.0088 0.0226 0.0849
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0048 0.0193
Loa Loa (eye worm) hypothetical protein 0.0182 0.0493 0.1933
Loa Loa (eye worm) twinkle helicase 0.0114 0.03 0.1175
Plasmodium falciparum heat shock protein 90, putative 0.004 0.0087 0.0343
Leishmania major cathepsin L-like protease 0.0886 0.251 0.9691
Onchocerca volvulus Cell death protein 3 homolog 0.0051 0.0118 0.0472
Echinococcus granulosus microtubule associated protein 2 0.0713 0.2015 0.7583
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.007 0.0172 0.0647
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Brugia malayi cathepsin L precursor 0.0182 0.0493 0.1933
Loa Loa (eye worm) hypothetical protein 0.0601 0.1692 0.6635
Plasmodium vivax LCCL domain-containing protein 0.0017 0.0023 0.0086
Echinococcus multilocularis neuropeptide FF receptor 2 0.0049 0.0113 0.0427
Brugia malayi follicle stimulating hormone receptor 0.0178 0.0482 0.1888
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0079 0.0199 0.0747
Onchocerca volvulus 0.0049 0.0113 0.0452
Echinococcus multilocularis serotonin receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0113 0.0445
Onchocerca volvulus 0.0049 0.0113 0.0452
Onchocerca volvulus 0.0049 0.0113 0.0452
Schistosoma mansoni hypothetical protein 0.0938 0.2657 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0099 0.0256 0.1013
Onchocerca volvulus Cathepsin L homolog 0.0886 0.251 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Giardia lamblia DINP protein human, muc B family 0.0014 0.0013 0.0115
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0012 0.0008 0.0026
Echinococcus granulosus enteropeptidase 0.0025 0.0045 0.017
Giardia lamblia Cysteine protease 0.0182 0.0493 0.4366
Trypanosoma cruzi DNA polymerase kappa, putative 0.0014 0.0013 0.0044
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0113 0.0427
Plasmodium falciparum heat shock protein 90 0.0069 0.017 0.0671
Echinococcus granulosus Tolloid protein 1 0.0025 0.0044 0.0164
Schistosoma mansoni adenoreceptor 0.0049 0.0113 0.0427
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Echinococcus multilocularis tissue type plasminogen activator 0.0032 0.0066 0.0249
Echinococcus granulosus apoptotic protease activating factor 1 0.0024 0.0043 0.0163
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0182 0.0493 0.196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Plasmodium vivax unspecified product 0.0467 0.1311 0.5219
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0045 0.017
Brugia malayi cathepsin F-like cysteine proteinase 0.0286 0.0791 0.31
Giardia lamblia Heat shock protein HSP 90-alpha 0.0069 0.017 0.1504
Trypanosoma brucei heat shock protein, putative 0.0069 0.017 0.0653
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0113 0.0427
Brugia malayi hypothetical protein 0.0025 0.0045 0.0177
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0113 0.0445
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Chlamydia trachomatis replicative DNA helicase 0.04 0.1116 1
Schistosoma mansoni heat shock protein 0.0069 0.017 0.0639
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0886 0.251 0.984
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0493 0.196
Echinococcus granulosus heat shock protein 90 0.0069 0.017 0.0639
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0058 0.0139 0.0546
Brugia malayi Cathepsin L-like precursor 0.0886 0.251 0.984
Schistosoma mansoni cathepsin F (C01 family) 0.0601 0.1692 0.6368
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0113 0.0427
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Mycobacterium ulcerans proteasome PrcB 0.0056 0.0133 0.1175
Echinococcus multilocularis cysteine protease 0.0886 0.251 0.9445
Treponema pallidum recombinase A 0.0112 0.0292 0.2609
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0113 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0023 0.0086
Onchocerca volvulus Cathepsin L homolog 0.0182 0.0493 0.1965
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Onchocerca volvulus Prolyl endopeptidase homolog 0.0079 0.0199 0.0791
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0066 0.0249
Toxoplasma gondii heat shock protein 90, putative 0.0069 0.017 0.0677
Echinococcus granulosus caspase 0.007 0.0172 0.0647
Echinococcus granulosus heat shock protein 0.0069 0.017 0.0639
Schistosoma mansoni heat shock protein 0.0069 0.017 0.0639
Trypanosoma cruzi DNA repair protein, putative 0.0034 0.0071 0.027
Echinococcus granulosus fmrfamide receptor 0.0049 0.0113 0.0427
Giardia lamblia Cathepsin L precursor 0.0182 0.0493 0.4366
Plasmodium falciparum endoplasmin, putative 0.005 0.0116 0.0456
Loa Loa (eye worm) hypothetical protein 0.0182 0.0493 0.1933
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0113 0.0445
Toxoplasma gondii heat shock protein HSP90 0.0069 0.017 0.0677
Schistosoma mansoni hypothetical protein 0.0058 0.0139 0.0524
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Trypanosoma brucei metacaspase 0.0026 0.0048 0.0184
Schistosoma mansoni heat shock protein 0.0046 0.0104 0.0391
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0135 0.0361 0.1437
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0032 0.0066 0.0257
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0113 0.0427
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0404 0.1129 0.4358
Plasmodium falciparum serine repeat antigen 4 0.0182 0.0493 0.196
Leishmania major cathepsin L-like protease 0.0914 0.259 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0058 0.0139 0.0524
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0045 0.017
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0113 0.0445
Schistosoma mansoni biogenic amine receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0286 0.0791 0.31
Plasmodium vivax proteasome subunit beta type-5, putative 0.0056 0.0133 0.0522
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0113 0.0445
Brugia malayi Tachykinin-like peptides receptor 99D 0.0049 0.0113 0.0445
Entamoeba histolytica cysteine proteinase, putative 0.0467 0.1311 0.5219
Loa Loa (eye worm) hypothetical protein 0.0026 0.0047 0.0184
Schistosoma mansoni biogenic amine receptor 0.0049 0.0113 0.0427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Brugia malayi MH2 domain containing protein 0.0089 0.0227 0.089
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0184 0.0499 0.1955
Leishmania major DNA polymerase kappa, putative 0.0014 0.0013 0.0044
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0182 0.0493 0.1933
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0182 0.0493 0.196
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0049 0.0113 0.0427
Schistosoma mansoni opsin-like receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) TK/ROR protein kinase 0.0032 0.0066 0.0259
Echinococcus multilocularis neurogenic locus notch protein 0.0009 0.0000000036994 0.000000013922
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0182 0.0493 0.196
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0056 0.0133 0.052
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0071 0.0175 0.0173
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0113 0.0427
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0901 0.255 0.9599
Brugia malayi Proteasome A-type and B-type family protein 0.0056 0.0133 0.052
Schistosoma mansoni jumonji/arid domain-containing protein 0.0088 0.0226 0.0849
Giardia lamblia Cathepsin L precursor 0.0182 0.0493 0.4366
Echinococcus granulosus integrin beta 2 0.0126 0.0333 0.1254
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Brugia malayi GnHR receptor homolog 0.0049 0.0113 0.0445
Loa Loa (eye worm) endoplasmin 0.0069 0.017 0.0666
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0023 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Toxoplasma gondii PA14 domain-containing protein 0.0017 0.0023 0.0092
Schistosoma mansoni protein phosphatase 2C 0.0023 0.004 0.0149
Loa Loa (eye worm) heat shock protein 75 0.0046 0.0104 0.0407
Plasmodium falciparum serine repeat antigen 2 0.0182 0.0493 0.196
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0045 0.017
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0404 0.1129 0.425
Entamoeba histolytica hypothetical protein 0.0107 0.0279 0.1107
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0009 0.0000000036994 0.00000001474
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0043 0.0374
Schistosoma mansoni hypothetical protein 0.0107 0.0279 0.1051
Mycobacterium ulcerans heat shock protein 90 0.0065 0.0158 0.1401
Giardia lamblia Cathepsin L precursor 0.0182 0.0493 0.4366
Trypanosoma brucei prolyl oligopeptidase, putative 0.0031 0.0063 0.024
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0182 0.0493 0.196
Loa Loa (eye worm) hypothetical protein 0.0058 0.0139 0.0546
Trypanosoma cruzi heat shock protein 90, putative 0.0029 0.0055 0.0208
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Echinococcus multilocularis fibrillin 1 0.003 0.0059 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0467 0.1311 0.5219
Schistosoma mansoni phd/f-box containing protein 0.0023 0.004 0.0149
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0063 0.0153 0.0601
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0886 0.251 1
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.001 0.0002 0.0006
Echinococcus multilocularis neuropeptide receptor A26 0.0049 0.0113 0.0427
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0031 0.0063 0.024
Plasmodium vivax endoplasmin, putative 0.0069 0.017 0.0671
Plasmodium falciparum serine repeat antigen 1 0.0182 0.0493 0.196
Giardia lamblia Hypothetical protein 0.0182 0.0493 0.4366
Brugia malayi EGF-like domain containing protein 0.0009 0.0000000036994 0.000000014505
Plasmodium falciparum LCCL domain-containing protein 0.0017 0.0023 0.0086
Trypanosoma brucei heat shock protein 90, putative 0.0069 0.017 0.0653
Echinococcus granulosus caspase 8 0.0026 0.0048 0.0182
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0675 0.1905 0.7171
Brugia malayi hypothetical protein 0.0057 0.0136 0.0532
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0013 0.0051
Entamoeba histolytica cysteine proteinase, putative 0.0467 0.1311 0.5219
Schistosoma mansoni pyruvate dehydrogenase 0.001 0.0002 0.0006
Plasmodium vivax vivapain-3 0.0467 0.1311 0.5219
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0182 0.0493 0.196
Brugia malayi cathepsin Z-like cysteine proteinase 0.0182 0.0493 0.1933
Schistosoma mansoni tar DNA-binding protein 0.0097 0.025 0.0941
Trypanosoma brucei oligopeptidase b 0.0031 0.0063 0.024
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0113 0.0427
Trypanosoma cruzi DNA repair protein, putative 0.0034 0.0071 0.027
Schistosoma mansoni neuropeptide receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0182 0.0493 0.1933
Brugia malayi neuropeptide F receptor 0.0049 0.0113 0.0445
Plasmodium falciparum metacaspase-like protein 0.0026 0.0048 0.0187
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.059 0.2313
Trichomonas vaginalis Antigenic protein P1, putative 0.0017 0.0023 0.0086
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0031 0.0061 0.0534
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3216 0.9176 0.9176
Trypanosoma cruzi metacaspase, putative 0.0026 0.0048 0.0181
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.021 0.0573 0.2278
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0113 0.0427
Trypanosoma cruzi metacaspase, putative 0.0026 0.0048 0.0181
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0901 0.255 0.9599
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0012 0.0008 0.0031
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0022 0.0036 0.0134
Schistosoma mansoni eyes absent homolog 0.0065 0.016 0.0604
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0113 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0113 0.0427
Echinococcus granulosus cysteine protease 0.0467 0.1311 0.4932
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.01
Leishmania major cathepsin L-like protease 0.0886 0.251 0.9691
Echinococcus granulosus neuropeptide receptor 0.0049 0.0113 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Echinococcus multilocularis cysteine protease 0.0886 0.251 0.9445
Brugia malayi jmjC domain containing protein 0.0023 0.004 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0006
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0025 0.0044 0.0171
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0102 0.0401
Plasmodium vivax serine-repeat antigen (SERA) 0.0182 0.0493 0.196
Brugia malayi N-terminal motif family protein 0.0135 0.0361 0.1414
Giardia lamblia Cathepsin B precursor 0.0182 0.0493 0.4366
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus multilocularis GPCR, family 2 0.0058 0.0139 0.0524
Schistosoma mansoni cathepsin C 0.0182 0.0493 0.1856
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0132 0.0352 0.1325
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0182 0.0493 0.1856
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Brugia malayi TAR-binding protein 0.0097 0.025 0.098
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0012 0.0045
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0056 0.0133 0.0392
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0062 0.0235
Onchocerca volvulus 0.0886 0.251 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0043 0.0125
Onchocerca volvulus 0.0049 0.0113 0.0452
Plasmodium vivax heat shock protein 86, putative 0.0069 0.017 0.0671
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Loa Loa (eye worm) hypothetical protein 0.0901 0.255 1
Echinococcus multilocularis dnaJ subfamily B 0.0243 0.0669 0.2517
Trypanosoma brucei prolyl endopeptidase 0.0079 0.0199 0.0764
Trypanosoma cruzi cysteine proteinase, putative 0.0467 0.1311 0.5058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0601 0.1692 0.674
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0113 0.0427
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0182 0.0493 0.1856
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0044 0.0171
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.019
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0184 0.0499 0.1955
Loa Loa (eye worm) fibroinase 0.0886 0.251 0.984
Entamoeba histolytica cysteine proteinase 1, putative 0.0467 0.1311 0.5219
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0012 0.0008 0.0027
Schistosoma mansoni amine GPCR 0.0049 0.0113 0.0427
Echinococcus multilocularis transmembrane protease serine 3 0.0025 0.0045 0.017
Schistosoma mansoni neuropeptide receptor 0.0049 0.0113 0.0427
Schistosoma mansoni hypothetical protein 0.0938 0.2657 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0123 0.0324 0.1221
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0013 0.0009 0.0034
Toxoplasma gondii isocitrate dehydrogenase 0.0012 0.0008 0.0033
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0012 0.0008 0.0031
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni hypothetical protein 0.0063 0.0153 0.0577
Trichomonas vaginalis conserved hypothetical protein 0.0182 0.0493 0.196
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0014 0.0013 0.0044
Brugia malayi jmjC domain containing protein 0.0023 0.004 0.0156
Echinococcus multilocularis caspase 3 0.0043 0.0097 0.0364
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0101 0.0262 0.1029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0113 0.0427
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0043 0.0374
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0031 0.0063 0.0237
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0031 0.0063 0.0237
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.0008 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0113 0.0427
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0182 0.0493 0.4366
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) trypsin family protein 0.0025 0.0045 0.0177
Echinococcus granulosus cathepsin L 0.0182 0.0493 0.1856
Trypanosoma cruzi heat shock protein 85, putative 0.0069 0.017 0.065
Giardia lamblia Cathepsin L precursor 0.0182 0.0493 0.4366
Onchocerca volvulus 0.0049 0.0113 0.0452
Brugia malayi hypothetical protein 0.0057 0.0136 0.0532
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0079 0.0199 0.0778
Trypanosoma cruzi C-terminal motor kinesin, putative 0.0075 0.0188 0.0721
Trypanosoma brucei heat shock protein, putative 0.0069 0.017 0.0653
Toxoplasma gondii proteasome subunit beta type, putative 0.0056 0.0133 0.0528
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0113 0.0427
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0629 0.1772 0.6841
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0048 0.0187
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0013 0.0049
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0025 0.0044 0.0171
Loa Loa (eye worm) integrin beta-2 0.017 0.0459 0.18
Echinococcus multilocularis isocitrate dehydrogenase 0.0012 0.0008 0.0031
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Entamoeba histolytica cysteine protease, putative 0.0182 0.0493 0.196
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0026 0.0215
Trypanosoma cruzi cruzipain precursor, putative 0.0286 0.0791 0.3049
Schistosoma mansoni endoplasmin 0.0069 0.017 0.0639
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0113 0.0445
Leishmania major metacaspase, putative 0.0026 0.0048 0.0181
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0043 0.0374
Echinococcus granulosus lysine specific demethylase 6a 0.0023 0.004 0.0149
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0013 0.0051
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0171
Echinococcus granulosus transmembrane protease serine 3 0.0025 0.0045 0.017
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Brugia malayi Papain family cysteine protease containing protein 0.0886 0.251 0.984
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0025 0.0045 0.017
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0013 0.0044
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0901 0.255 0.9848
Schistosoma mansoni cpg binding protein 0.0018 0.0025 0.0093
Entamoeba histolytica cysteine proteinase, putative 0.0467 0.1311 0.5219
Brugia malayi latrophilin 2 splice variant baaae 0.0126 0.0332 0.1303
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0182 0.0493 0.196
Echinococcus multilocularis kinesin family member c 0.0075 0.0188 0.0708
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0112 0.0292 0.2609
Trichomonas vaginalis DNA polymerase eta, putative 0.0014 0.0013 0.0046
Echinococcus granulosus serotonin receptor 0.0049 0.0113 0.0427
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0113 0.0427
Onchocerca volvulus 0.0049 0.0113 0.0452
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.014
Echinococcus granulosus geminin 0.0938 0.2657 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0058 0.0139 0.0524
Loa Loa (eye worm) hypothetical protein 0.0054 0.0127 0.0497
Brugia malayi prolyl oligopeptidase family protein 0.0079 0.0199 0.0778
Leishmania major cathepsin L-like protease 0.0914 0.259 1
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0886 0.251 1
Schistosoma mansoni neuropeptide receptor 0.0049 0.0113 0.0427
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0182 0.0493 0.1856
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0608 0.1714 0.645
Schistosoma mansoni Replicative DNA helicase 0.04 0.1116 0.4202
Trypanosoma brucei DNA polymerase IV, putative 0.0014 0.0013 0.0048
Trypanosoma brucei DNA polymerase IV, putative 0.0014 0.0013 0.0048
Toxoplasma gondii histone lysine methyltransferase SET1 0.0033 0.0069 0.0275
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0026 0.0096
Plasmodium vivax heat shock protein, putative 0.0261 0.0719 0.2859
Echinococcus granulosus neuropeptide s receptor 0.0049 0.0113 0.0427
Brugia malayi isocitrate dehydrogenase 0.0012 0.0008 0.0032
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0061 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Echinococcus multilocularis somatostatin receptor 0.0049 0.0113 0.0427
Onchocerca volvulus 0.0031 0.0062 0.0249
Schistosoma mansoni neuropeptide receptor 0.0049 0.0113 0.0427
Giardia lamblia Cathepsin L-like protease 0.0182 0.0493 0.4366
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Onchocerca volvulus DNA topoisomerase 2 homolog 0.001 0.0002 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0023 0.0021
Trypanosoma cruzi C-terminal motor kinesin, putative 0.0075 0.0188 0.0721
Schistosoma mansoni phosphatidylserine receptor 0.0023 0.004 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0467 0.1311 0.5219
Treponema pallidum replicative DNA helicase (dnaB) 0.04 0.1116 1
Entamoeba histolytica cysteine proteinase, putative 0.0886 0.251 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0113 0.0452
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0493 0.196
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0113 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0182 0.0493 0.196
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0113 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Onchocerca volvulus 0.0049 0.0113 0.0452
Toxoplasma gondii calcium binding egf domain-containing protein 0.0025 0.0044 0.0174
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0134
Loa Loa (eye worm) glutaminase 0.0283 0.0782 0.3066
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0037 0.008 0.0301
Onchocerca volvulus 0.0601 0.1692 0.6742
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0012 0.0008 0.0026
Brugia malayi RNA recognition motif domain containing protein 0.0097 0.025 0.098
Echinococcus granulosus somatostatin receptor 0.0049 0.0113 0.0427
Onchocerca volvulus 0.0032 0.0066 0.0263
Plasmodium vivax SET domain protein, putative 0.0031 0.0062 0.0243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0601 0.1692 0.674
Mycobacterium ulcerans glutaminase 0.0283 0.0782 0.6999
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0048 0.0181
Echinococcus granulosus tissue type plasminogen activator 0.0032 0.0066 0.0249
Trypanosoma cruzi oligopeptidase b 0.0031 0.0063 0.0237
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Echinococcus granulosus cathepsin b 0.0901 0.255 0.9599
Loa Loa (eye worm) hypothetical protein 0.0025 0.0043 0.017
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0099 0.0256 0.0982
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.01
Toxoplasma gondii calcium binding egf domain-containing protein 0.0025 0.0044 0.0174
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Leishmania major C-terminal motor kinesin, putative 0.0075 0.0188 0.0721
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.001 0.0002 0.0006
Giardia lamblia Cathepsin B precursor 0.0182 0.0493 0.4366
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0062 0.0235
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0038 0.0083 0.0324
Schistosoma mansoni cathepsin F (C01 family) 0.0886 0.251 0.9445
Brugia malayi Pre-SET motif family protein 0.0216 0.059 0.2313
Brugia malayi Cathepsin L-like cysteine proteinase 0.0601 0.1692 0.6635
Toxoplasma gondii PHD-finger domain-containing protein 0.0022 0.0036 0.0142
Schistosoma mansoni cathepsin s 0.0286 0.0791 0.2976
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0113 0.0427
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Chlamydia trachomatis recombinase RecA 0.0112 0.0292 0.2609
Brugia malayi Isocitrate dehydrogenase 0.0012 0.0008 0.0032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0177
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0178 0.0482 0.1888
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0107 0.0279 0.1051
Echinococcus multilocularis heat shock protein 0.0069 0.017 0.0639
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0025 0.0044 0.0171
Echinococcus granulosus expressed protein 0.0038 0.0083 0.0312
Giardia lamblia Cysteine protease 0.0182 0.0493 0.4366
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0886 0.251 0.9445
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0036 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Loa Loa (eye worm) heat shock protein 90 0.0069 0.017 0.0666
Trichomonas vaginalis heat shock protein, putative 0.0059 0.0141 0.0558
Entamoeba histolytica hypothetical protein 0.0107 0.0279 0.1107
Brugia malayi Papain family cysteine protease containing protein 0.0182 0.0493 0.1933
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0046 0.0104 0.0414
Echinococcus granulosus caspase 3 0.0043 0.0097 0.0364
Brugia malayi G protein-coupled receptor 0.0049 0.0113 0.0445
Plasmodium vivax JmjC domain containing protein 0.0023 0.004 0.0152
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0063 0.0153 0.0605
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0063 0.0153 0.0577
Echinococcus granulosus cathepsin l cysteine peptidase 0.0886 0.251 0.9445
Entamoeba histolytica cysteine proteinase 2 0.0467 0.1311 0.5219
Trichomonas vaginalis set domain proteins, putative 0.0245 0.0675 0.2685
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0886 0.251 0.9445
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0062 0.0235
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0013 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0493 0.196
Echinococcus multilocularis caspase 2 0.0051 0.0118 0.0446
Plasmodium vivax vivapain-2 0.0886 0.251 1
Toxoplasma gondii PA14 domain-containing protein 0.0017 0.0023 0.0092
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0048 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Plasmodium falciparum serine repeat antigen 7 0.0182 0.0493 0.196
Loa Loa (eye worm) hypothetical protein 0.0009 0.0000000036994 0.000000014505
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0467 0.1311 0.4932
Onchocerca volvulus Neurogenic locus notch homolog 0.0009 0.0000000036994 0.00000001474
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus granulosus GPCR family 2 0.0058 0.0139 0.0524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0113 0.0445
Echinococcus granulosus sex peptide receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0171
Brugia malayi Calcitonin receptor-like protein seb-1 0.0184 0.0499 0.1955
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0023 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Onchocerca volvulus 0.0049 0.0113 0.0452
Toxoplasma gondii isocitrate dehydrogenase 0.0012 0.0008 0.0033
Onchocerca volvulus 0.0024 0.0043 0.0172
Echinococcus granulosus neuropeptide receptor 0.0049 0.0113 0.0427
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Trichomonas vaginalis rotamase, putative 0.0099 0.0256 0.1013
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0038 0.0083 0.0324
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus multilocularis neuropeptide s receptor 0.0049 0.0113 0.0427
Echinococcus granulosus phd:f box containing protein 0.0023 0.004 0.0149
Onchocerca volvulus DNA topoisomerase 2 homolog 0.001 0.0002 0.0006
Brugia malayi Cathepsin L-like precursor 0.0886 0.251 0.984
Onchocerca volvulus 0.0257 0.0707 0.2819
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Loa Loa (eye worm) cysteine protease 0.0886 0.251 0.984
Entamoeba histolytica heat shock protein 90, putative 0.0069 0.017 0.0671
Onchocerca volvulus 0.0886 0.251 1
Echinococcus granulosus peregrin 0.0022 0.0036 0.0134
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0182 0.0493 0.1856
Brugia malayi Kinesin-like protein klp-3 0.0075 0.0188 0.0738
Loa Loa (eye worm) hypothetical protein 0.0065 0.016 0.0629
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0113 0.0427
Plasmodium vivax heat shock protein 90, putative 0.0046 0.0104 0.0408
Echinococcus multilocularis glycoprotein Antigen 5 0.0025 0.0045 0.017
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.001 0.0002 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni rotamase 0.0101 0.0262 0.0988
Loa Loa (eye worm) hypothetical protein 0.0601 0.1692 0.6635
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.01
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0062 0.0235
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0113 0.0427
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0182 0.0493 0.196
Trypanosoma brucei DNA polymerase IV, putative 0.0014 0.0013 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Plasmodium falciparum cysteine proteinase falcipain 1 0.0467 0.1311 0.5219
Schistosoma mansoni cpg binding protein 0.0017 0.0022 0.0083
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0182 0.0493 0.196
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0043 0.0166
Echinococcus multilocularis SHC transforming protein 3 0.0053 0.0124 0.0467
Trypanosoma cruzi heat shock protein 85, putative 0.0069 0.017 0.065
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.001 0.0002 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Brugia malayi Serotonin receptor 0.0049 0.0113 0.0445
Echinococcus granulosus dna polymerase eta 0.0014 0.0013 0.0049
Trypanosoma cruzi DNA polymerase kappa, putative 0.0014 0.0013 0.0044
Brugia malayi RE15519p 0.0049 0.0113 0.0445
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0099 0.0256 0.0982
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0031 0.0061 0.023
Toxoplasma gondii PHD-finger domain-containing protein 0.0022 0.0036 0.0142
Trypanosoma brucei C-terminal motor kinesin, putative 0.0075 0.0188 0.0724
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0059 0.0141 0.0532
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0058 0.0139 0.0524
Echinococcus granulosus jumonji domain containing protein 0.003 0.006 0.0227
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0023 0.004 0.0158
Trypanosoma cruzi Heat shock protein 83, putative 0.0069 0.017 0.065
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0036 0.014
Echinococcus multilocularis peregrin 0.0022 0.0036 0.0134
Echinococcus granulosus cathepsin L cysteine protease 0.0467 0.1311 0.4932
Plasmodium vivax unspecified product 0.0286 0.0791 0.3146
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0013 0.0046
Echinococcus granulosus DNA topoisomerase 2 alpha 0.001 0.0002 0.0006
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0113 0.0427
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0012 0.0008 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0886 0.251 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0113 0.0427
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0048 0.0193
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Brugia malayi Cytochrome P450 family protein 0.0013 0.0012 0.0045
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0043 0.017
Leishmania major cathepsin L-like protease 0.0886 0.251 0.9691
Loa Loa (eye worm) latrophilin receptor protein 2 0.0058 0.0139 0.0546
Echinococcus granulosus JmjC domain containing protein 4 0.0023 0.004 0.0149
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0079 0.0199 0.0747
Brugia malayi Cathepsin L-like precursor 0.0601 0.1692 0.6635
Giardia lamblia Cysteine protease 0.0182 0.0493 0.4366
Brugia malayi Cell death protein 3 precursor 0.0051 0.0118 0.0464
Brugia malayi cathepsin F-like cysteine proteinase 0.0182 0.0493 0.1933
Schistosoma mansoni hypothetical protein 0.0126 0.0332 0.1251
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0886 0.251 1
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Brugia malayi hypothetical protein 0.0065 0.016 0.0629
Echinococcus granulosus tachykinin peptides receptor 99D 0.0049 0.0113 0.0427
Trichomonas vaginalis heat shock protein, putative 0.005 0.0116 0.0456
Plasmodium vivax vivapain-2 0.0886 0.251 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0061 0.0233
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0113 0.0427
Mycobacterium tuberculosis Probable peptidase 0.0031 0.0063 0.0061
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0065 0.0158 0.1401
Loa Loa (eye worm) hypothetical protein 0.0063 0.0153 0.0601
Echinococcus multilocularis cpg binding protein 0.0018 0.0025 0.0093
Mycobacterium ulcerans hypothetical protein 0.0025 0.0045 0.0392
Leishmania major cysteine peptidase A (CPA) 0.0886 0.251 0.9691
Echinococcus multilocularis microtubule associated protein 2 0.0713 0.2015 0.7583
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0043 0.0166
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni DNA topoisomerase II 0.001 0.0002 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0043 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0467 0.1311 0.506
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0126 0.0332 0.1303
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0113 0.0427
Brugia malayi Integrin beta pat-3 precursor 0.017 0.0459 0.18
Toxoplasma gondii prolyl endopeptidase 0.0079 0.0199 0.0791
Brugia malayi Pre-SET motif family protein 0.0031 0.0062 0.0245
Loa Loa (eye worm) hypothetical protein 0.0182 0.0493 0.1933
Echinococcus multilocularis proteasome (prosome, macropain) 0.0056 0.0133 0.0499
Trypanosoma brucei C-terminal motor kinesin, putative 0.0075 0.0188 0.0724
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0156
Loa Loa (eye worm) jmjC domain-containing protein 0.0023 0.004 0.0156
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0113 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0182 0.0493 0.196
Schistosoma mansoni amine GPCR 0.0049 0.0113 0.0427
Echinococcus multilocularis cathepsin b 0.0901 0.255 0.9599
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0013 0.0051
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0113 0.0427
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Onchocerca volvulus Arrow homolog 0.0025 0.0044 0.0174
Echinococcus granulosus cpg binding protein 0.0018 0.0025 0.0093
Echinococcus granulosus g protein coupled receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0023 0.004 0.0158
Toxoplasma gondii cathepsin CPC2 0.0182 0.0493 0.1965
Schistosoma mansoni jumonji/arid domain-containing protein 0.0088 0.0226 0.0849
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0113 0.0427
Loa Loa (eye worm) glutaminase 2 0.0283 0.0782 0.3066
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0113 0.0445
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0056 0.0133 0.1174
Onchocerca volvulus 0.0025 0.0045 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Plasmodium vivax LCCL domain-containing protein 0.0017 0.0023 0.0086
Schistosoma mansoni microtubule-associated protein tau 0.0713 0.2015 0.7583
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Echinococcus multilocularis expressed protein 0.0038 0.0083 0.0312
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0113 0.0427
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Brugia malayi heat shock protein 90 0.0069 0.017 0.0666
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0182 0.0493 0.196
Brugia malayi Cathepsin L-like precursor 0.0886 0.251 0.984
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0113 0.0427
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0025 0.0045 0.017
Toxoplasma gondii preprocathepsin c precursor, putative 0.0182 0.0493 0.1965
Loa Loa (eye worm) TAR-binding protein 0.0097 0.025 0.098
Giardia lamblia Hypothetical protein 0.0182 0.0493 0.4366
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0493 0.196
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Loa Loa (eye worm) hypothetical protein 0.0184 0.0499 0.1955
Echinococcus granulosus hypothetical protein 0.0049 0.0113 0.0427
Brugia malayi Bromodomain containing protein 0.0022 0.0036 0.014
Schistosoma mansoni cpg binding protein 0.0018 0.0025 0.0093
Trypanosoma brucei cysteine peptidase C (CPC) 0.0404 0.1129 0.436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0493 0.196
Mycobacterium ulcerans DNA polymerase IV 0.0014 0.0013 0.0103
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0113 0.0445
Echinococcus granulosus heat shock protein 90 0.0059 0.0141 0.0532
Plasmodium falciparum cysteine repeat modular protein 1 0.0032 0.0066 0.0257
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.04 0.1116 0.3336
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0467 0.1311 0.4932
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0101 0.0262 0.1029
Brugia malayi Latrophilin receptor protein 2 0.0058 0.0139 0.0546
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0099 0.0256 0.0985
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Schistosoma mansoni caspase-7 (C14 family) 0.0051 0.0118 0.0446
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0886 0.251 1
Echinococcus multilocularis integrin beta 2 0.0126 0.0333 0.1254
Plasmodium falciparum proteasome subunit beta type-5 0.0056 0.0133 0.0522
Brugia malayi ORL1-like opioid receptor 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0025 0.0043 0.017
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0113 0.0427
Toxoplasma gondii heat shock protein 75, putative 0.0046 0.0104 0.0414
Loa Loa (eye worm) hypothetical protein 0.0031 0.0062 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Echinococcus multilocularis phd:f box containing protein 0.0023 0.004 0.0149
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0182 0.0493 0.1856
Schistosoma mansoni hypothetical protein 0.0243 0.0669 0.2517
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0048 0.0182
Trypanosoma cruzi cruzipain precursor, putative 0.0914 0.259 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0182 0.0493 0.196
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0012 0.0008 0.0031
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0023 0.004 0.0148
Echinococcus multilocularis kinesin protein KIFC3 0.0075 0.0188 0.0708
Echinococcus multilocularis enteropeptidase 0.0025 0.0045 0.017
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0043 0.017
Echinococcus multilocularis sex peptide receptor 0.0049 0.0113 0.0427
Schistosoma mansoni hypothetical protein 0.0049 0.0113 0.0427
Loa Loa (eye worm) CXXC zinc finger family protein 0.0017 0.0022 0.0086
Echinococcus multilocularis cathepsin L cysteine protease 0.0886 0.251 0.9445
Trypanosoma cruzi cysteine peptidase, putative 0.0886 0.251 0.9691
Brugia malayi cathepsin B-like cysteine proteinase 0.0901 0.255 1
Echinococcus granulosus caspase 2 0.0051 0.0118 0.0446
Brugia malayi jmjC domain containing protein 0.0023 0.004 0.0156
Echinococcus granulosus PHD finger protein rhinoceros 0.0022 0.0036 0.0134
Brugia malayi jmjC domain containing protein 0.0132 0.0352 0.138
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0113 0.0427
Brugia malayi CXXC zinc finger family protein 0.0017 0.0022 0.0086
Schistosoma mansoni opsin-like receptor 0.0049 0.0113 0.0427
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0058 0.0139 0.0524
Entamoeba histolytica cysteine protease, putative 0.0182 0.0493 0.196
Giardia lamblia Cathepsin L precursor 0.0182 0.0493 0.4366
Trypanosoma brucei Heat shock protein 83, putative 0.0069 0.017 0.0653
Trypanosoma cruzi oligopeptidase b 0.0031 0.0063 0.0237
Echinococcus granulosus allatostatin A receptor 0.0049 0.0113 0.0427
Onchocerca volvulus 0.0886 0.251 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0132 0.0352 0.1325
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni cathepsin B (C01 family) 0.0182 0.0493 0.1856
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0065 0.0158 0.0604
Trypanosoma brucei developmentally regulated phosphoprotein 0.001 0.0002 0.0003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0045 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Onchocerca volvulus 0.0025 0.0045 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0023 0.0086
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.001 0.0002 0.0006
Entamoeba histolytica heat shock protein 90, putative 0.0069 0.017 0.0671
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0156
Giardia lamblia Encystation-specific protease 0.0182 0.0493 0.4366
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0013 0.0048
Brugia malayi G-protein coupled receptor 0.0049 0.0113 0.0445
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0112 0.0292 0.087
Brugia malayi sulfakinin receptor protein 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0135 0.0361 0.1414
Plasmodium vivax LCCL domain-containing protein 0.0017 0.0023 0.0086
Entamoeba histolytica cysteine protease, putative 0.0182 0.0493 0.196
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0187
Schistosoma mansoni tar DNA-binding protein 0.0097 0.025 0.0941
Brugia malayi G-protein coupled receptor 0.0049 0.0113 0.0445
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0113 0.0427
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.001 0.0002 0.0003
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0182 0.0493 0.1933
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0182 0.0493 0.196
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0113 0.0445
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0182 0.0493 0.196
Echinococcus multilocularis apoptotic protease activating factor 1 0.0024 0.0043 0.0163
Leishmania major proteasome beta 5 subunit, putative 0.0056 0.0133 0.0506
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0014 0.0013 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0043 0.0374
Echinococcus granulosus g protein coupled receptor 0.0049 0.0113 0.0427
Echinococcus granulosus orexin receptor type 2 0.0049 0.0113 0.0427
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0043 0.0374
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Plasmodium falciparum serine repeat antigen 8 0.0182 0.0493 0.196
Brugia malayi PHD-finger family protein 0.0022 0.0036 0.014
Echinococcus granulosus dna polymerase kappa 0.0014 0.0013 0.0049
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni amine GPCR 0.0049 0.0113 0.0427
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.001 0.0002 0.0006
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0012 0.0046
Brugia malayi Cathepsin L-like precursor 0.0286 0.0791 0.31
Echinococcus multilocularis G protein coupled receptor 139 0.0049 0.0113 0.0427
Brugia malayi Probable DNA topoisomerase II 0.001 0.0002 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0048 0.0187
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0062 0.0235
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0493 0.196
Giardia lamblia Cysteine protease 0.0182 0.0493 0.4366
Schistosoma mansoni DNA polymerase eta 0.0014 0.0013 0.0049
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0062 0.0235
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni hypothetical protein 0.0058 0.0139 0.0524
Giardia lamblia Cathepsin B precursor 0.0404 0.1129 1
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0113 0.0427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0467 0.1311 0.506
Trypanosoma cruzi cysteine peptidase, putative 0.0286 0.0791 0.3049
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0182 0.0493 0.196
Brugia malayi Serotonin receptor 0.0049 0.0113 0.0445
Trypanosoma brucei unspecified product 0.0014 0.0013 0.0048
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0467 0.1311 0.4932
Echinococcus granulosus expressed protein 0.0101 0.0262 0.0988
Entamoeba histolytica cysteine proteinase, putative 0.0886 0.251 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0013 0.0012
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.001 0.0002 0.0003
Brugia malayi hypothetical protein 0.0049 0.0113 0.0445
Onchocerca volvulus 0.0049 0.0113 0.0452
Giardia lamblia Cathepsin B precursor 0.0182 0.0493 0.4366
Brugia malayi Cathepsin L-like precursor 0.0601 0.1692 0.6635
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0113 0.0427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0914 0.259 1
Plasmodium falciparum serine repeat antigen 6 0.0182 0.0493 0.196
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0467 0.1311 0.5058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0182 0.0493 0.196
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Echinococcus multilocularis geminin 0.0938 0.2657 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0099 0.0256 0.0982
Schistosoma mansoni biogenic amine receptor 0.0049 0.0113 0.0427
Brugia malayi Melatonin receptor type 1A 0.0049 0.0113 0.0445
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0493 0.196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0113 0.0427
Schistosoma mansoni egf-like domain protein 0.0025 0.0044 0.0164
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0113 0.0445
Echinococcus granulosus laminin 0.0025 0.0044 0.0164
Schistosoma mansoni transcription factor LCR-F1 0.0107 0.0279 0.1051
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0182 0.0493 0.196
Plasmodium falciparum serine repeat antigen 9 0.0182 0.0493 0.196
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0048 0.0187
Echinococcus multilocularis dna polymerase kappa 0.0014 0.0013 0.0049
Leishmania major hypothetical protein, conserved 0.0032 0.0066 0.0249
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Entamoeba histolytica hypothetical protein 0.0107 0.0279 0.1107
Leishmania major heat shock protein 83-1 0.0069 0.017 0.065
Brugia malayi Cathepsin L-like precursor 0.0886 0.251 0.984
Schistosoma mansoni tar DNA-binding protein 0.0097 0.025 0.0941
Brugia malayi cathepsin L-like cysteine proteinase 0.0182 0.0493 0.1933
Echinococcus granulosus neuropeptide receptor A26 0.0049 0.0113 0.0427
Brugia malayi Hsp90 protein 0.0046 0.0104 0.0407
Giardia lamblia PHD finger protein 15 0.0022 0.0036 0.0316
Brugia malayi Kelch motif family protein 0.0026 0.0047 0.0184
Onchocerca volvulus Cathepsin F homolog 0.0886 0.251 1
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0023 0.0086
Giardia lamblia Kinesin-14 0.0075 0.0188 0.1666
Loa Loa (eye worm) hypothetical protein 0.0257 0.0707 0.2774
Onchocerca volvulus 0.0886 0.251 1
Entamoeba histolytica cysteine protease, putative 0.0182 0.0493 0.196
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Trypanosoma cruzi DNA polymerase kappa, putative 0.0014 0.0013 0.0044
Giardia lamblia Cathepsin B precursor 0.0404 0.1129 1
Trypanosoma cruzi cysteine peptidase, putative 0.0914 0.259 1
Echinococcus multilocularis jumonji domain containing protein 0.003 0.006 0.0227
Entamoeba histolytica cysteine protease, putative 0.0182 0.0493 0.196
Trypanosoma brucei heat shock protein 84, putative 0.0046 0.0104 0.0398
Echinococcus granulosus jumonji domain containing 1A 0.0023 0.004 0.0149
Schistosoma mansoni cathepsin S (C01 family) 0.0182 0.0493 0.1856
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0023 0.004 0.0148
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0043 0.0374
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Brugia malayi hypothetical protein 0.0026 0.0047 0.0184
Onchocerca volvulus 0.0182 0.0493 0.1965
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0056 0.0133 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0013 0.0048
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0182 0.0493 0.196
Echinococcus granulosus neuropeptide FF receptor 2 0.0049 0.0113 0.0427
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0113 0.0427
Trypanosoma brucei heat shock protein, putative 0.0069 0.017 0.0653
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0013 0.0049
Loa Loa (eye worm) hypothetical protein 0.0182 0.0493 0.1933
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0038 0.0083 0.033
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0023 0.004 0.0151
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.01
Schistosoma mansoni hypothetical protein 0.0032 0.0066 0.0249
Entamoeba histolytica cysteine protease, putative 0.0467 0.1311 0.5219
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0113 0.0427
Trypanosoma brucei heat shock protein, putative 0.0069 0.017 0.0653
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0404 0.1129 0.4358
Schistosoma mansoni hypothetical protein 0.0049 0.0113 0.0427
Echinococcus multilocularis prolyl endopeptidase 0.0079 0.0199 0.0747
Brugia malayi DNA topoisomerase II, alpha isozyme 0.001 0.0002 0.0006
Brugia malayi fibroinase precursor 0.0182 0.0493 0.1933
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0056 0.0133 0.0506
Giardia lamblia Grp94/Hsp90 0.0065 0.0158 0.1397
Mycobacterium leprae Conserved hypothetical protein 0.1178 0.3344 1
Giardia lamblia Cathepsin B precursor 0.0182 0.0493 0.4366
Brugia malayi neuropeptide F receptor 0.0049 0.0113 0.0445
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0177
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0113 0.0427
Toxoplasma gondii PA14 domain-containing protein 0.0017 0.0023 0.0092
Plasmodium falciparum JmjC domain-containing protein, putative 0.0023 0.004 0.0152
Trypanosoma brucei heat shock protein, putative 0.0069 0.017 0.0653
Loa Loa (eye worm) hypothetical protein 0.0182 0.0493 0.1933
Trypanosoma cruzi metacaspase, putative 0.0026 0.0048 0.0181
Onchocerca volvulus 0.0049 0.0113 0.0452
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0113 0.0427
Loa Loa (eye worm) hypothetical protein 0.0601 0.1692 0.6635
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0043 0.0125
Onchocerca volvulus 0.0049 0.0113 0.0452
Leishmania major cathepsin L-like protease 0.0914 0.259 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0113 0.0427
Trichomonas vaginalis endoplasmin, putative 0.005 0.0116 0.0456
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0445
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0113 0.0427
Onchocerca volvulus 0.0886 0.251 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0113 0.0427
Leishmania major cathepsin L-like protease 0.0886 0.251 0.9691
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0286 0.0791 0.31
Echinococcus multilocularis Tolloid protein 1 0.0025 0.0044 0.0164
Treponema pallidum heat shock protein 90 0.0065 0.0158 0.1401
Brugia malayi kinase, mitochondrial precursor 0.001 0.0002 0.0006
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0056 0.0133 0.0506
Echinococcus granulosus dnaJ subfamily B 0.0243 0.0669 0.2517
Brugia malayi Trypsin family protein 0.0025 0.0045 0.0177
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0113 0.0427
Entamoeba histolytica cysteine proteinase, putative 0.0601 0.1692 0.674
Brugia malayi Endoplasmin precursor 0.0069 0.017 0.0666
Schistosoma mansoni caspase-3 (C14 family) 0.007 0.0172 0.0647
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0169
Trichomonas vaginalis heat shock protein, putative 0.0065 0.0158 0.0623
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0031 0.0063 0.0549
Brugia malayi larval opioid receptor 0.0049 0.0113 0.0445
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0113 0.0427
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0045 0.017
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0025 0.0044 0.0164
Leishmania major hypothetical protein, conserved 0.0023 0.004 0.0148
Brugia malayi hypothetical protein 0.0107 0.0279 0.1095
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0182 0.0493 0.1856
Brugia malayi notch-like transmembrane receptor 0.0009 0.0000000036994 0.000000014505
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0464
Schistosoma mansoni opsin-like receptor 0.0049 0.0113 0.0427
Trypanosoma cruzi major cysteine proteinase, putative 0.021 0.0573 0.2208
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0026 0.0024
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0062 0.0249

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.5 uM Inhibition of Bacillus anthracis lethal toxin-induced mouse RAW264.7 cell death preincubated for 1 hr followed by lethal toxin challenge measured after 4 hrs ChEMBL. 24900841

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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