Detailed information for compound 2072858

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.314 | Formula: C16H26BrN5O2
  • H donors: 1 H acceptors: 3 LogP: 1.42 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cnn(c1C)C)CN1CCN(C(=O)C1)C1CCCC1.Br
  • InChi: 1S/C16H25N5O2.BrH/c1-12-14(9-17-19(12)2)18-15(22)10-20-7-8-21(16(23)11-20)13-5-3-4-6-13;/h9,13H,3-8,10-11H2,1-2H3,(H,18,22);1H
  • InChiKey: VBCMBJNGSGNIKH-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.002 0.0008 0.0008
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0008 0.0008
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Plasmodium vivax amine transporter, putative 0.0027 0.0012 0.328
Leishmania major DNA polymerase eta, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0013 0.0003 0.0002
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis serotonin receptor 0.002 0.0008 0.0008
Plasmodium falciparum monocarboxylate transporter, putative 0.0013 0.0003 0.0983
Echinococcus granulosus sodium dependent phosphate transport protein 1 0.0013 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.002 0.0008 0.0008
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0007 0.219
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.3941
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Giardia lamblia NADH oxidase lateral transfer candidate 0.0019 0.0007 0.9419
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0012 0.0012
Onchocerca volvulus 0.002 0.0008 0.0006
Echinococcus multilocularis MFS transporter ceroid lipofuscinosis neuronal 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.002 0.0008 0.0008
Trichomonas vaginalis glucose-6-phosphate translocase, putative 0.0013 0.0003 0.0071
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni sodium/chloride dependent transporter 0.0158 0.0102 0.0102
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0007 0.049
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0013 0.0003 0.0071
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Echinococcus granulosus dna polymerase eta 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0007 0.0007
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0014 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0007 0.9788
Echinococcus multilocularis thioredoxin glutathione reductase 0.0054 0.0031 0.0031
Treponema pallidum sodium- and chloride- dependent transporter 0.0158 0.0102 1
Onchocerca volvulus Sialin homolog 0.0013 0.0003 0.0002
Echinococcus granulosus alpha 1A adrenergic receptor 0.002 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0007 0.0007
Onchocerca volvulus 0.0013 0.0003 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Leishmania major C-8 sterol isomerase-like protein 1.304 0.8938 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0008 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Onchocerca volvulus Sialin homolog 0.0013 0.0003 0.0002
Onchocerca volvulus 0.0013 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 1.304 0.8938 0.8938
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0008 0.0008
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Loa Loa (eye worm) solute carrier family 6 member 4 0.0158 0.0102 0.0102
Echinococcus granulosus 7tm_1 domain containing protein 0.002 0.0008 0.0008
Trypanosoma brucei protein associated with differentiation 3, putative 0.0013 0.0003 0.0001
Entamoeba histolytica major facilitator superfamily protein 0.0013 0.0003 0.2334
Plasmodium falciparum thioredoxin reductase 0.0019 0.0007 0.219
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0008 0.0008
Echinococcus multilocularis alpha 1A adrenergic receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.0013 0.0003 0.0002
Echinococcus multilocularis sugar phosphate exchanger solute carrier family 0.0013 0.0003 0.0003
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Giardia lamblia Multidrug resistance protein B 0.0013 0.0003 0.4227
Onchocerca volvulus 0.0013 0.0003 0.0002
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0011 0.0001 0.0001
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0011 0.0001 0.0001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0158 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma brucei trypanothione reductase 0.0054 0.0031 0.0033
Brugia malayi AKH receptor 0.002 0.0008 0.0008
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0011 0.0001 0.0001
Brugia malayi Cation transporter family protein 0.0011 0.0001 0.0001
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Trypanosoma brucei drug resistence protein, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0007
Loa Loa (eye worm) thioredoxin reductase 0.0054 0.0031 0.0031
Brugia malayi GnHR receptor homolog 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0007 0.0006
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0013 0.0003 0.0003
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0007 0.0006
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0007 0.0006
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0027 0.0012 0.0012
Echinococcus granulosus peptide allatostatin:somatostatin 0.002 0.0008 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0901 0.0612 0.0612
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0011 0.0001 0.0001
Trypanosoma cruzi drug resistance protein, putative 0.0013 0.0003 0.0001
Echinococcus granulosus solute carrier family 43 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Echinococcus multilocularis feline leukemia virus subgroup C 0.0013 0.0003 0.0003
Toxoplasma gondii exonuclease III APE 0.0019 0.0007 0.2216
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0007 0.0441
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0003
Brugia malayi follicle stimulating hormone receptor 0.0252 0.0167 0.0167
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0008 0.0008
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0007 0.0305
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0007 0.0282
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Brugia malayi putative neuropeptide receptor NPR1 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.6665 0.4566 0.4566
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0004 0.1208
Plasmodium vivax thioredoxin reductase, putative 0.0054 0.0031 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0158 0.0102 0.0102
Onchocerca volvulus 0.0013 0.0003 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Plasmodium falciparum monocarboxylate transporter, putative 0.0013 0.0003 0.0983
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Trypanosoma cruzi protein associated with differentiation 4, putative 0.0013 0.0003 0.0001
Trypanosoma cruzi C-8 sterol isomerase, putative 1.304 0.8938 1
Schistosoma mansoni biogenic amine receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0006
Brugia malayi ERG2 and Sigma1 receptor like protein 1.304 0.8938 0.8938
Schistosoma mansoni neuropeptide f receptor 76f 0.002 0.0008 0.0008
Brugia malayi Dopamine receptor protein 2 0.002 0.0008 0.0008
Echinococcus multilocularis biogenic amine (5HT) receptor 0.002 0.0008 0.0008
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Loa Loa (eye worm) hypothetical protein 0.0158 0.0102 0.0102
Brugia malayi G protein-coupled receptor F59B2.13 0.002 0.0008 0.0008
Giardia lamblia Sugar transport family protein 0.0013 0.0003 0.4227
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0008 0.0008
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) hippocampus abundant transcript 1a 0.0013 0.0003 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0008 0.0008
Brugia malayi G-protein coupled receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.0027 0.0012 0.0011
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus granulosus somatostatin receptor 0.002 0.0008 0.0008
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4227
Echinococcus granulosus neuropeptides capa receptor 0.002 0.0008 0.0008
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0011 0.0001 0.0001
Trypanosoma cruzi hypothetical protein 0.0013 0.0003 0.0001
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Trypanosoma brucei riboflavin transporter 0.0013 0.0003 0.0001
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0013 0.0003 0.0983
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis neuropeptide receptor A26 0.002 0.0008 0.0008
Onchocerca volvulus 0.0013 0.0003 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.2334
Echinococcus multilocularis vesicular acetylcholine transporter 1.4587 1 1
Leishmania major MFS transporter, putative 0.0013 0.0003 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0008 0.0008
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0007 0.1338
Echinococcus multilocularis allatostatin A receptor 0.002 0.0008 0.0008
Giardia lamblia hypothetical protein 0.0013 0.0003 0.4227
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0003 0.0983
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0008 0.0008
Brugia malayi Abnormal catecholamine distribution protein 1 0.0013 0.0003 0.0003
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0017 0.0017
Echinococcus granulosus Solute carrier family 22 5 0.0013 0.0003 0.0003
Echinococcus granulosus biogenic amine 5HT receptor 0.002 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0008 0.0008
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0008 0.0008
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0008 0.0008
Echinococcus multilocularis synaptic vesicle 2 protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0013 0.0003 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Brugia malayi Tachykinin-like peptides receptor 99D 0.002 0.0008 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.002 0.0008 0.0008
Schistosoma mansoni ap endonuclease 0.0019 0.0007 0.0007
Schistosoma mansoni drug efflux protein-related 0.0013 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0008 0.0008
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0011 0.0001 0.0001
Schistosoma mansoni biogenic amine receptor 0.002 0.0008 0.0008
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0011 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0012 0.0012
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0003 0.0983
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni peptide (allatostatin)-like receptor 0.002 0.0008 0.0008
Brugia malayi Serotonin/octopamine receptor family protein 7 0.002 0.0008 0.0008
Plasmodium falciparum thioredoxin reductase 0.0054 0.0031 1
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis synaptic vesicular amine transporter 0.0013 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.002 0.0008 0.0008
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0007 0.219
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0007 0.9531
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Trypanosoma cruzi integral membrane transport protein, putative 0.0013 0.0003 0.0001
Brugia malayi excitatory GABA receptor EXP-1A 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0049 0.0027 0.0026
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus glycine receptor subunit beta 0.0011 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0008 0.0008
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0012 0.0012
Trypanosoma cruzi major facilitator superfamily, putative 0.0013 0.0003 0.0001
Brugia malayi Cation transporter family protein 0.0011 0.0001 0.0001
Brugia malayi Serotonin receptor 0.002 0.0008 0.0008
Schistosoma mansoni survival motor neuron protein 0.0049 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0009 0.0384
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis fmrfamide receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.0027 0.0012 0.0011
Mycobacterium tuberculosis Probable dehydrogenase 0.0124 0.0079 0.8888
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0001 0.0001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni sodium-dependent phosphate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus synaptic vesicle 2 protein 0.0013 0.0003 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0017 0.0017
Onchocerca volvulus Sugar phosphate exchanger 3 homolog 0.0013 0.0003 0.0002
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus multilocularis Hippocampus abundant transcript 1 protein 0.0013 0.0003 0.0003
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Schistosoma mansoni adenylate cyclase 0.0013 0.0003 0.0003
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Echinococcus multilocularis MFS transporter ceroid lipofuscinosis neuronal 0.0013 0.0003 0.0003
Echinococcus multilocularis neuropeptide s receptor 0.002 0.0008 0.0008
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.3941
Leishmania major transporter-like protein 0.0013 0.0003 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.0031 0.0033
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0007 0.0006
Echinococcus granulosus hypothetical protein 0.002 0.0008 0.0008
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.002 0.0008 0.0008
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0158 0.0102 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus vesicular acetylcholine transporter 1.4587 1 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0006
Echinococcus granulosus synaptic vesicular amine transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0008 0.0008
Schistosoma mansoni biogenic amine receptor 0.002 0.0008 0.0008
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0011 0.0001 0.0001
Brugia malayi larval opioid receptor 0.002 0.0008 0.0008
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0007 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0007 0.0007
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0017 0.0017
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Onchocerca volvulus 0.002 0.0008 0.0006
Schistosoma mansoni selectively expressed in embryonic epithelia protein-1 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0008 0.0008
Plasmodium falciparum glutathione reductase 0.0019 0.0007 0.219
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0013 0.0003 0.0002
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0011 0.0001 0.0001
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0007 0.2203
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0011 0.0001 0.0001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0007 0.9188
Echinococcus granulosus glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0007 0.0305
Plasmodium falciparum metabolite/drug transporter, putative 0.0013 0.0003 0.0983
Giardia lamblia DINP protein human, muc B family 0.0019 0.0007 1
Brugia malayi Dopamine receptor 0.002 0.0008 0.0008
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0008 0.0008
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis vesicular glutamate transporter 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis sodium dependent phosphate transport protein 1 0.0013 0.0003 0.0003
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0007 0.0006
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0007
Giardia lamblia Major facilitator family transporter 0.0013 0.0003 0.4227
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Schistosoma mansoni opsin-like receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.002 0.0008 0.0006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.002 0.0008 0.0008
Echinococcus multilocularis glycine receptor subunit beta 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.002 0.0008 0.0008
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0011 0.0001 0.0001
Echinococcus granulosus Hippocampus abundant transcript 1 protein 0.0013 0.0003 0.0003
Echinococcus granulosus dro:myosuppressin receptor 0.002 0.0008 0.0008
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0027 0.0012 0.0012
Echinococcus granulosus Glycerol 3 phosphate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0009 0.0384
Onchocerca volvulus 0.0273 0.0181 0.018
Schistosoma mansoni hypothetical protein 0.0366 0.0245 0.0245
Brugia malayi neuropeptide F receptor 0.002 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.002 0.0008 0.0008
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0007 0.0006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0008 0.0008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.002 0.0008 0.0008
Plasmodium falciparum glutathione reductase 0.0054 0.0031 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Trichomonas vaginalis hypothetical protein 0.0013 0.0003 0.0071
Schistosoma mansoni histamine h1 receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.002 0.0008 0.0008
Plasmodium vivax glutathione reductase, putative 0.0054 0.0031 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0007 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0006
Onchocerca volvulus 0.0013 0.0003 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Toxoplasma gondii hypothetical protein 0.0027 0.0012 0.3941
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0124 0.0079 0.8888
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Onchocerca volvulus 0.002 0.0008 0.0006
Echinococcus multilocularis orexin receptor type 2 0.002 0.0008 0.0008
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.002 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus thyrotropin releasing hormone receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.002 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0004 0.0291
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.2334
Loa Loa (eye worm) hypothetical protein 0.0158 0.0102 0.0102
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0124 0.0079 0.8888
Brugia malayi Cation transporter family protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) ACC-1 protein 0.0011 0.0001 0.0001
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus granulosus protein spinster 0.0013 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0006
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0011 0.0001 0.0001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.002 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Echinococcus granulosus vesicular glutamate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus feline leukemia virus subgroup C 0.0013 0.0003 0.0003
Trypanosoma cruzi protein associated with differentiation 8, putative 0.0013 0.0003 0.0001
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.0158 0.0158
Onchocerca volvulus 0.0027 0.0012 0.0011
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus granulosus serotonin transporter 0.0158 0.0102 0.0102
Echinococcus granulosus tm gpcr rhodopsin 0.0901 0.0612 0.0612
Schistosoma mansoni ap endonuclease 0.0019 0.0007 0.0007
Echinococcus granulosus solute carrier family 43 0.0013 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.002 0.0008 0.0008
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0007 0.045
Schistosoma mansoni phosphate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0012 0.328
Trypanosoma brucei Protein Associated with Differentiation 1 0.0013 0.0003 0.0001
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0007 0.0007
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0007 0.0007
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus g-protein coupled receptor 0.002 0.0008 0.0008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.002 0.0008 0.0008
Entamoeba histolytica major facilitator superfamily transporter, putative 0.0013 0.0003 0.2334
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0011 0.0001 0.0001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.002 0.0008 0.0008
Leishmania major DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Schistosoma mansoni myosin xvIII 0.002 0.0008 0.0008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0017 0.5593
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0006
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0008 0.0008
Entamoeba histolytica major facilitator superfamily protein 0.0013 0.0003 0.2334
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0012 0.0012
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0013 0.0003 0.0983
Schistosoma mansoni amine GPCR 0.002 0.0008 0.0008
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Onchocerca volvulus 0.002 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0012 0.0012
Onchocerca volvulus 0.0013 0.0003 0.0002
Echinococcus multilocularis G protein coupled receptor 139 0.002 0.0008 0.0008
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0013 0.0003 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0007 0.0006
Brugia malayi Melatonin receptor type 1A 0.002 0.0008 0.0008
Schistosoma mansoni solute carrier family 17 member 7 (vesicular glutamate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0003 0.0983
Echinococcus granulosus bloom syndrome protein 0.0022 0.0009 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0007 0.0007
Echinococcus multilocularis dna polymerase eta 0.0019 0.0007 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0011 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis g-protein coupled receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) LGC-31 protein 0.0011 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Toxoplasma gondii hypothetical protein 0.0027 0.0012 0.3941
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0007 0.0006
Echinococcus granulosus synaptic vesicle 2 protein 0.0013 0.0003 0.0003
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0007 0.9377
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0019 0.0007 0.408
Schistosoma mansoni neuropeptide receptor 0.002 0.0008 0.0008
Schistosoma mansoni tetracycline-efflux transporter 0.0013 0.0003 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0007 0.049
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.002 0.0008 0.0008
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi integral membrane transport protein, putative 0.0013 0.0003 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma brucei unspecified product 0.0019 0.0007 0.0006
Echinococcus granulosus neuropeptide receptor 0.002 0.0008 0.0008
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0007 0.0006
Echinococcus granulosus nAChR subunit 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0034 0.0017 0.0016
Echinococcus multilocularis somatostatin receptor 0.002 0.0008 0.0008
Echinococcus multilocularis neuropeptide receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus g protein coupled receptor 0.002 0.0008 0.0008
Entamoeba histolytica major facilitator superfamily protein 0.0013 0.0003 0.2334
Toxoplasma gondii hypothetical protein 0.0013 0.0003 0.0983
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0124 0.0079 0.8888
Toxoplasma gondii hypothetical protein 0.0013 0.0003 0.0983
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein 0.0013 0.0003 0.0001
Echinococcus granulosus g protein coupled receptor 0.002 0.0008 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.002 0.0008 0.0008
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Brugia malayi sulfakinin receptor protein 0.002 0.0008 0.0008
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni drug transporter 0.0013 0.0003 0.0003
Echinococcus granulosus glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Trichomonas vaginalis transport proetin, putative 0.0013 0.0003 0.0071
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis fmrfamide receptor 0.002 0.0008 0.0008
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Brugia malayi transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.002 0.0008 0.0008
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0013 0.0003 0.0003
Brugia malayi glutathione reductase 0.0054 0.0031 0.0031
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0007 0.219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.002 0.0008 0.0008
Echinococcus granulosus sex peptide receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Echinococcus multilocularis transfer RNA-Leu 0.0013 0.0003 0.0003
Schistosoma mansoni phosphate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni alpha-1 adrenergic receptor 0.002 0.0008 0.0008
Echinococcus multilocularis nAChR subunit 0.0011 0.0001 0.0001
Trypanosoma brucei Protein Associated with Differentiation, putative 0.0013 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0366 0.0245 0.0245
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0011 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0008 0.0008
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0012 0.0012
Echinococcus granulosus MFS transporter ceroid lipofuscinosis neuronal 0.0013 0.0003 0.0003
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Brugia malayi neuropeptide F receptor 0.002 0.0008 0.0008
Toxoplasma gondii zinc finger protein 36 family 3 protein 0.0013 0.0003 0.0983
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0007 0.9788
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Brugia malayi Serotonin receptor 0.002 0.0008 0.0008
Trypanosoma brucei transporter, putative 0.0013 0.0003 0.0001
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0017 0.0017
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0027 0.0012 0.0012
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0252 0.0167 0.0167
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Echinococcus multilocularis solute carrier family 43 0.0013 0.0003 0.0003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.002 0.0008 0.0008
Mycobacterium tuberculosis Probable reductase 0.0124 0.0079 0.8888
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma brucei transporter, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0007 1
Giardia lamblia Multidrug resistance protein B 0.0013 0.0003 0.4227
Schistosoma mansoni opsin-like receptor 0.002 0.0008 0.0008
Echinococcus multilocularis vesicular glutamate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0007 0.0006
Onchocerca volvulus Vesicular acetylcholine transporter homolog 1.4587 1 1
Toxoplasma gondii hypothetical protein 0.0013 0.0003 0.0983
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis neuropeptide receptor 0.002 0.0008 0.0008
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0013 0.0003 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0138 0.0089 1
Leishmania major hypothetical protein, unknown function 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0007 0.0006
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.002 0.0008 0.0008
Schistosoma mansoni sodium-dependent amino acid transporter 0.0027 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Onchocerca volvulus 0.002 0.0008 0.0006
Echinococcus multilocularis Glycerol 3 phosphate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.024 0.0158 0.0158
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.002 0.0008 0.0008
Onchocerca volvulus Neuropeptide F receptor homolog 0.002 0.0008 0.0006
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4227
Entamoeba histolytica sucrose transporter, putative 0.0013 0.0003 0.2334
Echinococcus granulosus thioredoxin glutathione reductase 0.0054 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0239 0.0158 0.0158
Trypanosoma brucei C-8 sterol isomerase, putative 1.304 0.8938 1
Echinococcus granulosus MFS transporter ceroid lipofuscinosis neuronal 0.0013 0.0003 0.0003
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0027 0.0012 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0007 0.0007
Echinococcus multilocularis G-protein coupled receptor, putative 0.002 0.0008 0.0008
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0007 0.2216
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0138 0.0089 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Onchocerca volvulus 0.002 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0007 0.219
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Giardia lamblia MDR-type permease 0.0013 0.0003 0.4227
Onchocerca volvulus 0.002 0.0008 0.0006
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0158 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0007 0.0006
Schistosoma mansoni transport proetin (smap-4-related) 0.0013 0.0003 0.0003
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0008 0.0008
Onchocerca volvulus 0.0013 0.0003 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0003 0.0001
Onchocerca volvulus 0.002 0.0008 0.0006
Leishmania major trypanothione reductase 0.0054 0.0031 0.0033
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.002 0.0008 0.0006
Onchocerca volvulus 0.002 0.0008 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus granulosus allatostatin A receptor 0.002 0.0008 0.0008
Brugia malayi Thioredoxin reductase 0.0054 0.0031 0.0031
Echinococcus granulosus sugar phosphate exchanger 3 0.0013 0.0003 0.0003
Onchocerca volvulus Putative transporter 0.0013 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0008 0.0008
Echinococcus multilocularis sugar phosphate exchanger 3 0.0013 0.0003 0.0003
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Onchocerca volvulus 0.002 0.0008 0.0006
Leishmania major hypothetical protein, unknown function 0.0013 0.0003 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0008 0.0008
Onchocerca volvulus 0.0013 0.0003 0.0002
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0007 0.0009
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Schistosoma mansoni adenoreceptor 0.002 0.0008 0.0008
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0007 0.1338
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0007 0.0006
Trypanosoma brucei protein associated with differentiation 5, putative 0.0013 0.0003 0.0001
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Trypanosoma brucei major facilitator superfamily protein (MFS), putative 0.0013 0.0003 0.0001
Echinococcus multilocularis serotonin receptor 0.002 0.0008 0.0008
Brugia malayi G-protein coupled receptor 0.002 0.0008 0.0008
Trypanosoma brucei transporter protein, putative 0.0013 0.0003 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) melatonin receptor type 1A 0.002 0.0008 0.0008
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Echinococcus granulosus dna polymerase kappa 0.0019 0.0007 0.0007
Schistosoma mansoni sugar transporter 0.0013 0.0003 0.0003
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0011 0.0001 0.0001
Plasmodium falciparum pantothenate transporter 0.0013 0.0003 0.0983
Schistosoma mansoni amine GPCR 0.002 0.0008 0.0008
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0013 0.0003 0.0983
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Echinococcus granulosus glycine receptor subunit beta 0.0011 0.0001 0.0001
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.002 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.002 0.0008 0.0008
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0012 0.0012
Echinococcus multilocularis g protein coupled receptor 0.002 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Onchocerca volvulus 0.0013 0.0003 0.0002
Trypanosoma brucei protein associated with differentiation 6, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis geminin 0.0366 0.0245 0.0245
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0019 0.0007 0.8993
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0013 0.0003 0.0071
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni opsin-like receptor 0.002 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0008 0.0008
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Onchocerca volvulus Putative solute carrier family 17, member 7 0.0013 0.0003 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.0034 0.0017 0.0017
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Echinococcus multilocularis sex peptide receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.0013 0.0003 0.0002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.002 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Onchocerca volvulus EG:103B4.3 protein homolog 0.0013 0.0003 0.0002
Echinococcus granulosus sugar phosphate exchanger 0.0013 0.0003 0.0003
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0011 0.0001 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Schistosoma mansoni sodium/sialic acid cotransporter 0.0013 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0006
Echinococcus granulosus 7TM GPCR rhodopsin 0.002 0.0008 0.0008
Schistosoma mansoni growth hormone secretagogue receptor 0.002 0.0008 0.0008
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Trypanosoma cruzi major facilitator superfamily, putative 0.0013 0.0003 0.0001
Trypanosoma brucei Protein Associated with Differentiation 0.0013 0.0003 0.0001
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.002 0.0008 0.0008
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) norepinephrine transporter 0.0158 0.0102 0.0102
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0124 0.0079 0.8888
Trypanosoma cruzi major facilitator superfamily, putative 0.0013 0.0003 0.0001
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0013 0.0003 0.0003
Brugia malayi probable sodium-dependent inorganic phosphate cotransporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) TYRA-2 protein 0.002 0.0008 0.0008
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0013 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0011 0.0001 0.0001
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0013 0.0003 0.0071
Echinococcus granulosus neuropeptide receptor 0.002 0.0008 0.0008
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0007 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.002 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0017 0.0017
Brugia malayi G protein-coupled receptor 0.002 0.0008 0.0008
Schistosoma mansoni DNA polymerase eta 0.0019 0.0007 0.0007
Plasmodium falciparum transporter, putative 0.0027 0.0012 0.3941
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Schistosoma mansoni neuropeptide receptor 0.002 0.0008 0.0008
Trichomonas vaginalis set domain proteins, putative 0.0273 0.0181 1
Schistosoma mansoni vesicular amine transporter 0.0013 0.0003 0.0003
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0011 0.0001 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Onchocerca volvulus 0.002 0.0008 0.0006
Trypanosoma brucei protein associated with differentiation 7, putative 0.0013 0.0003 0.0001
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.3941
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0007 0.0006
Schistosoma mansoni hypothetical protein 0.0049 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Schistosoma mansoni biogenic amine (dopamine) receptor 0.002 0.0008 0.0008
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.0027 0.0012 0.0012
Loa Loa (eye worm) ACC-1 protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0013 0.0003 0.0003
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni vesicular amine transporter 0.0013 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0003
Brugia malayi ORL1-like opioid receptor 0.002 0.0008 0.0008
Schistosoma mansoni neuropeptide receptor 0.002 0.0008 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0006
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.002 0.0008 0.0008
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Onchocerca volvulus 0.002 0.0008 0.0006
Schistosoma mansoni neuropeptide receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.002 0.0008 0.0006
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0007 0.0007
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0003 0.0983
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0017 0.0017
Brugia malayi Dopamine receptor protein 1 0.002 0.0008 0.0008
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.002 0.0008 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0008 0.0008
Trypanosoma cruzi protein associated with differentiation 8, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Leishmania major monocarboxylate transporter-like protein 0.0013 0.0003 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0008 0.0008
Brugia malayi putative neuropeptide receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.0071
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0011 0.0001 0.0001
Brugia malayi Pre-SET motif family protein 0.024 0.0158 0.0158
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0138 0.0089 1
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni transporter spinster-related 0.0013 0.0003 0.0003
Echinococcus multilocularis synaptic vesicle 2 protein 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0007 0.1367
Brugia malayi hypothetical protein 0.0239 0.0158 0.0158
Echinococcus granulosus g protein coupled receptor 0.002 0.0008 0.0008
Schistosoma mansoni feline leukemia virus subgroup C receptor-related 0.0013 0.0003 0.0003
Trypanosoma brucei protein associated with differentiation 8, putative 0.0013 0.0003 0.0001
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus neuropeptide s receptor 0.002 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Schistosoma mansoni sialin (solute carrier family 17 member 5) (sodium/sialic acid cotransporter) (ast) (membrane glycoprotein hp59) 0.0013 0.0003 0.0003
Echinococcus multilocularis dro:myosuppressin receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0007 0.0282
Schistosoma mansoni vesicular acetylcholine transporter 1.4587 1 1
Loa Loa (eye worm) glutathione reductase 0.0054 0.0031 0.0031
Brugia malayi transporter 0.0013 0.0003 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0124 0.0079 0.8888
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Echinococcus granulosus neuropeptide FF receptor 2 0.002 0.0008 0.0008
Echinococcus multilocularis neuropeptides capa receptor 0.002 0.0008 0.0008
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0983
Trichomonas vaginalis Hexuronate transporter, putative 0.0013 0.0003 0.0071
Echinococcus granulosus vesicular glutamate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Brugia malayi Hypothetical transporter C09D4.1 0.0013 0.0003 0.0003
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0019 0.0007 0.8993
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0007 1
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0011 0.0001 0.0001
Schistosoma mansoni biogenic amine (5HT) receptor 0.002 0.0008 0.0008
Onchocerca volvulus 0.002 0.0008 0.0006
Schistosoma mansoni amine GPCR 0.002 0.0008 0.0008
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Schistosoma mansoni sugar transporter 0.0013 0.0003 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.0138 0.0089 1
Leishmania major hypothetical protein, conserved in leishmania 0.0013 0.0003 0.0001
Echinococcus granulosus neuropeptide receptor A26 0.002 0.0008 0.0008
Echinococcus multilocularis serotonin transporter 0.0158 0.0102 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.0071
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0011 0.0001 0.0001
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) neuropeptide F receptor 0.002 0.0008 0.0008
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0007 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.002 0.0008 0.0008
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0007 0.0286
Trypanosoma brucei unspecified product 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0019 0.0007 0.8993
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0009 0.0009
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0007 0.0007
Plasmodium falciparum amino acid transporter, putative 0.0027 0.0012 0.3941
Schistosoma mansoni neuropeptide F-like receptor 0.002 0.0008 0.0008
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.002 0.0008 0.0008
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0012 0.0012
Echinococcus granulosus serotonin receptor 0.002 0.0008 0.0008
Toxoplasma gondii thioredoxin reductase 0.0054 0.0031 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Trypanosoma brucei protein associated with differentiation 4, putative 0.0013 0.0003 0.0001
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4227
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4227
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0003 0.0001
Trypanosoma brucei unspecified product 0.0013 0.0003 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Entamoeba histolytica phosphate transporter, putative 0.0013 0.0003 0.2334
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0006
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Echinococcus multilocularis neuropeptide FF receptor 2 0.002 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Echinococcus granulosus G protein coupled receptor 139 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni feline leukemia virus subgroup C receptor-related 0.0013 0.0003 0.0003
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Plasmodium vivax SET domain protein, putative 0.0034 0.0017 0.5113
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) serotonin transporter b 0.0158 0.0102 0.0102
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0027 0.0027
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0007 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Brugia malayi gonadotropin-releasing hormone receptor 2 0.002 0.0008 0.0008
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.002 0.0008 0.0008
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.002 0.0008 0.0008
Echinococcus multilocularis solute carrier family 43 0.0013 0.0003 0.0003
Echinococcus multilocularis protein spinster 0.0013 0.0003 0.0003
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0011 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0007 0.0286
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Trypanosoma cruzi MFS transporter, putative 0.0013 0.0003 0.0001
Schistosoma mansoni amine GPCR 0.002 0.0008 0.0008
Schistosoma mansoni drug efflux protein-related 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis glycine receptor subunit beta 0.0011 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0003 0.0071
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0006
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Brugia malayi RE15519p 0.002 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Onchocerca volvulus Uncharacterized transporter homolog 0.0013 0.0003 0.0002
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 1.4587 1 1
Schistosoma mansoni protein transport protein Sec13 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.002 0.0008 0.0008
Echinococcus multilocularis g protein coupled receptor 0.002 0.0008 0.0008
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.0158 0.0158
Leishmania major integral membrane transport protein, putative,drug resistence protein, putative 0.0013 0.0003 0.0001
Leishmania major transporter, putative,major facilitator superfamily protein (MFS), putative 0.0013 0.0003 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.002 0.0008 0.0008
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0054 0.0031 0.3294
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2334
Trypanosoma cruzi major facilitator superfamily, putative 0.0013 0.0003 0.0001
Trypanosoma brucei transporter, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis tachykinin peptides receptor 99D 0.002 0.0008 0.0008
Giardia lamblia TM efflux prot 0.0013 0.0003 0.4227
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4227
Loa Loa (eye worm) RecQ helicase 0.0022 0.0009 0.0009
Echinococcus granulosus geminin 0.0366 0.0245 0.0245
Echinococcus granulosus fmrfamide receptor 0.002 0.0008 0.0008
Echinococcus granulosus tachykinin peptides receptor 99D 0.002 0.0008 0.0008
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0011 0.0001 0.0001
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0011 0.0001 0.0001
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus orexin receptor type 2 0.002 0.0008 0.0008
Onchocerca volvulus 0.0013 0.0003 0.0002

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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