Detailed information for compound 2072984

Basic information

Technical information
  • TDR Targets ID: 2072984
  • Name: N,N-dimethylquinoline-2,4-diamine
  • MW: 187.241 | Formula: C11H13N3
  • H donors: 1 H acceptors: 1 LogP: 1.97 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(c1cc(N)c2c(n1)cccc2)C
  • InChi: 1S/C11H13N3/c1-14(2)11-7-9(12)8-5-3-4-6-10(8)13-11/h3-7H,1-2H3,(H2,12,13)
  • InChiKey: OXLDRPPQCHUJAO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (4-amino-2-quinolyl)-dimethyl-amine
  • BAS 00232407
  • CBDivE_008496
  • Oprea1_387820
  • Oprea1_378112

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei RNA helicase, putative 0.0218 0.0145 0.0752
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0004
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0037 0.0039
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.8339 0.6192 0.6192
Loa Loa (eye worm) hypothetical protein 0.0153 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0084 0.0046 0.0046
Echinococcus multilocularis alpha glucosidase 0.0116 0.007 0.007
Trichomonas vaginalis alpha-glucosidase, putative 0.2373 0.175 0.2822
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0169 0.0109 0.0109
Brugia malayi hypothetical protein 0.0074 0.0038 0.0038
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0153 0.0097 0.0104
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.8339 0.6192 0.6192
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0013 0.0013
Brugia malayi Glycosyl hydrolases family 38 protein 0.0044 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0128 0.0079 0.0079
Brugia malayi Melibiase family protein 0.0153 0.0097 0.0097
Trichomonas vaginalis glucosylceramidase, putative 0.5471 0.4057 0.655
Schistosoma mansoni hypothetical protein 0.0238 0.0161 0.0173
Schistosoma mansoni alpha-amylase 0.0116 0.007 0.0075
Brugia malayi Trehalase family protein 0.0128 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.022 0.0147 0.0158
Loa Loa (eye worm) TAR-binding protein 0.0072 0.0037 0.0037
Echinococcus granulosus mitogen activated protein kinase 0.0043 0.0015 0.0015
Echinococcus multilocularis lysosomal alpha mannosidase 0.008 0.0043 0.0043
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0034 0.011
Trypanosoma brucei lysosomal alpha-mannosidase precursor, putative 0.008 0.0043 0.0159
Trypanosoma brucei glucosidase, putative 0.2373 0.175 1
Schistosoma mansoni hypothetical protein 0.0218 0.0145 0.0156
Onchocerca volvulus Glucosylceramidase homolog 0.5471 0.4057 0.5771
Trichomonas vaginalis glucosylceramidase, putative 0.8339 0.6192 1
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.033 0.0229 0.1289
Schistosoma mansoni bile acid beta-glucosidase-related 0.7586 0.5631 0.6047
Trichomonas vaginalis glycogen debranching enzyme, putative 0.033 0.0229 0.0364
Schistosoma mansoni beta-mannosidase 0.0097 0.0055 0.0059
Brugia malayi RNA binding protein 0.0072 0.0037 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.8339 0.6192 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.2338 0.1724 0.9852
Trichomonas vaginalis Periplasmic beta-glucosidase precursor, putative 0.0039 0.0012 0.0013
Trichomonas vaginalis alpha-glucosidase, putative 0.2373 0.175 0.2822
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0111 0.0066 0.01
Echinococcus granulosus mitogen activated protein kinase 3 0.0043 0.0015 0.0015
Trichomonas vaginalis maltase-glucoamylase, putative 0.1415 0.1037 0.1669
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.2373 0.175 0.2822
Entamoeba histolytica beta-galactosidase, putative 0.0202 0.0133 0.0741
Loa Loa (eye worm) alpha-L-fucosidase 0.0253 0.0171 0.0171
Mycobacterium leprae Putative uncharacterized protein ML2045 0.0116 0.007 0.5
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0034 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.5766 0.4276 0.6904
Trichomonas vaginalis beta-mannosidase, putative 0.0097 0.0055 0.0083
Schistosoma mansoni cpg binding protein 0.0034 0.0009 0.0009
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0116 0.007 0.007
Loa Loa (eye worm) trehalase 0.0128 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0044 0.0016 0.0016
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0043 0.0015 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.1415 0.1037 0.1669
Brugia malayi Alpha-L-fucosidase family protein 0.0253 0.0171 0.0171
Brugia malayi Glycosyl hydrolases family 31 protein 0.1415 0.1037 0.1037
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0037 0.0039
Brugia malayi Trehalase family protein 0.0128 0.0079 0.0079
Schistosoma mansoni alpha-amylase 0.0116 0.007 0.0075
Treponema pallidum hypothetical protein 0.0044 0.0016 0.5
Entamoeba histolytica glycogen debranching enzyme, putative 0.033 0.0229 0.1289
Brugia malayi Amylo-alpha-1,6-glucosidase family protein 0.033 0.0229 0.0229
Onchocerca volvulus 0.0032 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0128 0.0079 0.0079
Onchocerca volvulus 0.0128 0.0079 0.0112
Loa Loa (eye worm) hypothetical protein 0.0852 0.0617 0.0617
Loa Loa (eye worm) hypothetical protein 0.0044 0.0016 0.0016
Onchocerca volvulus 0.0044 0.0016 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.2373 0.175 0.2822
Loa Loa (eye worm) RNA binding protein 0.0072 0.0037 0.0037
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0034 0.0034
Onchocerca volvulus 0.0128 0.0079 0.0112
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0153 0.0097 0.0104
Loa Loa (eye worm) TRE-2 protein 0.0128 0.0079 0.0079
Trypanosoma cruzi lysosomal alpha-mannosidase precursor, putative 0.008 0.0043 0.0159
Loa Loa (eye worm) hypothetical protein 0.0028 0.0004 0.0004
Leishmania major glycosyl hydrolase-like protein 0.1415 0.1037 0.589
Loa Loa (eye worm) hypothetical protein 0.0064 0.0031 0.0031
Brugia malayi Glycosyl hydrolases family 38 protein 0.0044 0.0016 0.0016
Echinococcus multilocularis trehalose 6 phosphate hydrolase 0.0028 0.0004 0.0004
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.1415 0.1037 0.1475
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.2373 0.175 1
Echinococcus granulosus non lysosomal glucosylceramidase 0.7586 0.5631 0.5631
Giardia lamblia Kinase, CMGC MAPK 0.0043 0.0015 0.0044
Echinococcus granulosus alpha glucosidase 0.0116 0.007 0.007
Echinococcus granulosus lysosomal alpha glucosidase 1.3453 1 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0016 0.0016
Schistosoma mansoni cpg binding protein 0.0032 0.0007 0.0008
Schistosoma mansoni ceramide glucosyltransferase 0.7592 0.5636 0.6052
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0169 0.0109 0.0109
Trichomonas vaginalis alpha-mannosidase 2c1, putative 0.0044 0.0016 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0169 0.0109 0.017
Echinococcus multilocularis dnaJ subfamily B 0.0463 0.0328 0.0328
Trichomonas vaginalis alpha-glucosidase, putative 0.2373 0.175 0.2822
Trichomonas vaginalis alpha-glucosidase, putative 0.1415 0.1037 0.1669
Brugia malayi TAR-binding protein 0.0072 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.1415 0.1037 0.1037
Trichomonas vaginalis alpha-glucosidase, putative 0.1415 0.1037 0.1669
Brugia malayi trehalase I 0.0044 0.0016 0.0016
Brugia malayi hypothetical protein 0.0044 0.0016 0.0016
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0153 0.0097 0.0097
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0116 0.007 0.007
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0034 0.011
Brugia malayi lysosomal alpha-mannosidase 0.0044 0.0016 0.0016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0153 0.0097 0.0104
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.0028 0.0004 0.0004
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0153 0.0097 0.0104
Loa Loa (eye worm) alpha amylase 0.0116 0.007 0.007
Trypanosoma brucei lysosomal alpha-mannosidase precursor, putative 0.0067 0.0033 0.0102
Brugia malayi hypothetical protein 0.0128 0.0079 0.0079
Loa Loa (eye worm) amylo-alpha-1,6-glucosidase 0.0161 0.0103 0.0103
Loa Loa (eye worm) beta-glucuronidase 0.0161 0.0103 0.0103
Echinococcus granulosus trehalose 6 phosphate hydrolase 0.0028 0.0004 0.0004
Onchocerca volvulus 0.0044 0.0016 0.0023
Schistosoma mansoni hypothetical protein 0.0028 0.0004 0.0004
Echinococcus granulosus tar DNA binding protein 0.0072 0.0037 0.0037
Echinococcus multilocularis glycogen debranching enzyme 0.033 0.0229 0.0229
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.1415 0.1037 0.589
Trypanosoma cruzi hypothetical protein, conserved 0.2373 0.175 1
Schistosoma mansoni alpha-amylase 0.0116 0.007 0.0075
Schistosoma mansoni hypothetical protein 0.0424 0.0299 0.0321
Echinococcus multilocularis fucosidase, alpha L 1, tissue 0.0418 0.0294 0.0294
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0015 0.0018
Brugia malayi CXXC zinc finger family protein 0.0032 0.0007 0.0007
Echinococcus granulosus ceramide glucosyltransferase 0.7592 0.5636 0.5636
Echinococcus granulosus neutral alpha glucosidase AB 0.2373 0.175 0.175
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0153 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0128 0.0079 0.0079
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0034 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.8339 0.6192 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0016 0.0016
Brugia malayi Ceramide glucosyltransferase 0.7592 0.5636 0.5636
Trypanosoma cruzi hypothetical protein, conserved 0.2373 0.175 1
Echinococcus multilocularis alpha mannosidase 2 0.0044 0.0016 0.0016
Schistosoma mansoni alpha-amylase 0.0116 0.007 0.0075
Entamoeba histolytica oligo-1,6-glucosidase, putative 0.0116 0.007 0.0377
Echinococcus multilocularis non lysosomal glucosylceramidase 0.7586 0.5631 0.5631
Brugia malayi RNA recognition motif domain containing protein 0.0072 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.033 0.0229 0.0229
Chlamydia trachomatis glycogen hydrolase 0.0028 0.0004 0.5
Loa Loa (eye worm) glycosyl hydrolase family 38 protein 0.0044 0.0016 0.0016
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0034 0.0037
Trypanosoma cruzi lysosomal alpha-mannosidase precursor, putative 0.008 0.0043 0.0159
Echinococcus granulosus dnaJ subfamily B 0.0463 0.0328 0.0328
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.0044 0.0016 0.0017
Giardia lamblia 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase 0.033 0.0229 0.0886
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0037 0.0039
Plasmodium vivax hypothetical protein, conserved 0.026 0.0177 0.5
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0153 0.0097 0.0097
Onchocerca volvulus Trehalase homolog 0.0128 0.0079 0.0112
Loa Loa (eye worm) hypothetical protein 0.0128 0.0079 0.0079
Leishmania major alpha glucosidase II subunit, putative 0.2373 0.175 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0029 0.0144
Schistosoma mansoni hypothetical protein 0.0463 0.0328 0.0352
Loa Loa (eye worm) hypothetical protein 0.1136 0.0829 0.0829
Schistosoma mansoni bile acid beta-glucosidase-related 0.7586 0.5631 0.6047
Trichomonas vaginalis trehalase, putative 0.0128 0.0079 0.0121
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0034 0.0172
Mycobacterium ulcerans beta-glucosidase BglS 0.0039 0.0012 0.0278
Brugia malayi hypothetical protein 0.0044 0.0016 0.0016
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.008 0.0043 0.0046
Trichomonas vaginalis alpha-glucosidase, putative 0.1415 0.1037 0.1669
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0079 0.0121
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0034 0.0036
Toxoplasma gondii melibiase subfamily protein 0.0153 0.0097 0.0533
Schistosoma mansoni beta-galactosidase 0.0852 0.0617 0.0663
Echinococcus multilocularis mitogen activated protein kinase 0.0043 0.0015 0.0015
Echinococcus granulosus fucosidase alpha L 1 tissue 0.0418 0.0294 0.0294
Echinococcus granulosus glycogen debranching enzyme 0.033 0.0229 0.0229
Brugia malayi Trehalase family protein 0.0128 0.0079 0.0079
Echinococcus multilocularis glucan (1,4 alpha), branching enzyme 1 0.0028 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.8339 0.6192 1
Onchocerca volvulus 0.0128 0.0079 0.0112
Echinococcus multilocularis tar DNA binding protein 0.0072 0.0037 0.0037
Trichomonas vaginalis beta-glucosidase, putative 0.0335 0.0233 0.037
Trichomonas vaginalis glucosylceramidase, putative 0.5471 0.4057 0.655
Trichomonas vaginalis alpha-glucosidase, putative 0.1415 0.1037 0.1669
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0153 0.0097 0.0104
Echinococcus multilocularis mitogen activated protein kinase 3 0.0043 0.0015 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0037 0.0039
Loa Loa (eye worm) trehalase 0.0128 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0039 0.0012 0.0013
Giardia lamblia Ceramide glucosyltransferase 0.3441 0.2546 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.026 0.0177 0.5
Echinococcus multilocularis beta galactosidase 0.0852 0.0617 0.0617
Trichomonas vaginalis glycoside hydrolases, putative 0.0335 0.0233 0.037
Onchocerca volvulus 0.0128 0.0079 0.0112
Onchocerca volvulus Ceramide glucosyltransferase homolog 0.7592 0.5636 0.8017
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0064 0.0031 0.0031
Onchocerca volvulus 0.9464 0.703 1
Brugia malayi trehalase 0.0044 0.0016 0.0016
Trichomonas vaginalis maltase-glucoamylase, putative 0.2373 0.175 0.2822
Echinococcus granulosus lysosomal alpha mannosidase 0.008 0.0043 0.0043
Loa Loa (eye worm) trehalase 0.0044 0.0016 0.0016
Trichomonas vaginalis alpha-mannosidase, putative 0.0044 0.0016 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.5471 0.4057 0.655
Echinococcus granulosus cpg binding protein 0.0034 0.0009 0.0009
Loa Loa (eye worm) trehalase 0.0128 0.0079 0.0079
Schistosoma mansoni alpha-l-fucosidase 0.0253 0.0171 0.0184
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.1415 0.1037 0.1669
Brugia malayi Glycosyl hydrolases family 31 protein 0.2373 0.175 0.175
Brugia malayi Trehalase family protein 0.0044 0.0016 0.0016
Loa Loa (eye worm) trehalase 0.0044 0.0016 0.0016
Schistosoma mansoni alpha-glucosidase 1.253 0.9313 1
Brugia malayi MAP kinase sur-1 0.0043 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0128 0.0079 0.0079
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0153 0.0097 0.015
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.1415 0.1037 0.5916
Trichomonas vaginalis sucrase-isomaltase, putative 0.2338 0.1724 0.278
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.2373 0.175 0.175
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.1415 0.1037 0.1669
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.2373 0.175 0.2822
Mycobacterium tuberculosis Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-glucoamylase) (lysosomal alpha-glucosidas 0.0116 0.007 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0007 0.0007
Schistosoma mansoni ceramide glucosyltransferase 0.7592 0.5636 0.6052
Mycobacterium ulcerans alpha-mannosidase 0.0044 0.0016 0.0413
Onchocerca volvulus 0.0128 0.0079 0.0112
Schistosoma mansoni starch branching enzyme II 0.0028 0.0004 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.2373 0.175 0.2822
Loa Loa (eye worm) hypothetical protein 0.512 0.3796 0.3796
Trypanosoma brucei glycosyl hydrolase-like protein 0.1415 0.1037 0.589
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.2373 0.175 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0016 0.0016
Loa Loa (eye worm) ceramide glucosyltransferase 0.7592 0.5636 0.5636
Loa Loa (eye worm) TRE-1 protein 0.0128 0.0079 0.0079
Brugia malayi Trehalase protein 5 0.0044 0.0016 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.5766 0.4276 0.6904
Brugia malayi manba-prov protein 0.0097 0.0055 0.0055
Trichomonas vaginalis glycogen debranching enzyme, putative 0.033 0.0229 0.0364
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0072 0.0037 0.0037
Brugia malayi Glycosyl hydrolases family 38 protein 0.0044 0.0016 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0015 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0298 0.0205 0.0326
Brugia malayi 1,4-alpha-glucan branching enzyme 0.0028 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.5471 0.4057 0.655
Echinococcus multilocularis beta D xylosidase 2 0.0039 0.0012 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.8339 0.6192 1
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0015 0.0018
Echinococcus multilocularis lysosomal alpha glucosidase 1.3453 1 1
Echinococcus multilocularis lysosomal alpha glucosidase 1.3453 1 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.1415 0.1037 0.589
Echinococcus multilocularis cpg binding protein 0.0034 0.0009 0.0009
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0034 0.0034
Chlamydia trachomatis 1,4-alpha-glucan branching enzyme 0.0028 0.0004 0.5
Brugia malayi Trehalase family protein 0.0128 0.0079 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0015 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.8339 0.6192 1
Trichomonas vaginalis beta-galactosidase, putative 0.0298 0.0205 0.0326
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0043 0.0015 0.0063
Mycobacterium ulcerans trehalose synthase TreS 0.0116 0.007 0.2268
Echinococcus multilocularis ceramide glucosyltransferase 0.7592 0.5636 0.5636
Schistosoma mansoni alpha glucosidase 0.2373 0.175 0.1879
Trichomonas vaginalis glucosylceramidase, putative 0.5471 0.4057 0.655
Schistosoma mansoni alpha-glucosidase 1.253 0.9313 1
Mycobacterium ulcerans alpha-L-fucosidase 0.0418 0.0294 1
Schistosoma mansoni mannosidase alpha class 2a 0.0044 0.0016 0.0017
Mycobacterium tuberculosis Trehalose synthase TreS 0.0116 0.007 1
Trichomonas vaginalis glucosylceramidase, putative 0.5471 0.4057 0.655
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 1.3453 1 1
Echinococcus multilocularis bile acid beta glucosidase 0.7586 0.5631 0.5631
Trichomonas vaginalis glucosylceramidase, putative 0.5471 0.4057 0.655
Echinococcus multilocularis neutral alpha glucosidase AB 0.2373 0.175 0.175
Schistosoma mansoni alpha-amylase 0.0116 0.007 0.0075
Trichomonas vaginalis glycoside hydrolase, putative 0.0413 0.0291 0.0464
Entamoeba histolytica hypothetical protein 0.0039 0.0012 0.0046
Echinococcus granulosus beta galactosidase 0.0852 0.0617 0.0617
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0013 0.0013
Echinococcus granulosus bile acid beta glucosidase 0.7586 0.5631 0.5631
Loa Loa (eye worm) alpha amylase 0.0116 0.007 0.007
Brugia malayi hypothetical protein 0.0044 0.0016 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0015 0.0016
Echinococcus granulosus beta D xylosidase 2 0.0039 0.0012 0.0012
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0034 0.011
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0037 0.0039
Brugia malayi Trehalase family protein 0.0044 0.0016 0.0016
Schistosoma mansoni cpg binding protein 0.0034 0.0009 0.0009
Echinococcus granulosus glucan 14 alpha branching enzyme 1 0.0028 0.0004 0.0004
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0111 0.0066 0.01
Brugia malayi Beta-glucuronidase precursor 0.0161 0.0103 0.0103
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0153 0.0097 0.0104
Loa Loa (eye worm) hypothetical protein 0.0044 0.0016 0.0016

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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