Detailed information for compound 2073562

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 644.751 | Formula: C38H44O9
  • H donors: 2 H acceptors: 5 LogP: 6.64 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=CCc1c2O[C@]34[C@H]5C[C@H](C(=O)[C@]3(C/C=C(\C(=O)O)/C)OC5(C)C)C3C4(C(=O)c2c(c2c1O[C@](C)(CCC=C(C)C)C=C2)O)O3)C
  • InChi: 1S/C38H44O9/c1-19(2)10-9-15-35(8)16-14-22-27(39)26-29(23(28(22)44-35)12-11-20(3)4)45-38-25-18-24(32-37(38,46-32)31(26)41)30(40)36(38,47-34(25,6)7)17-13-21(5)33(42)43/h10-11,13-14,16,24-25,32,39H,9,12,15,17-18H2,1-8H3,(H,42,43)/b21-13-/t24-,25+,32?,35-,36+,37?,38-/m1/s1
  • InChiKey: WCBINTABDRSBOM-BXQNXPOQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi uridine phosphorylase family protein 0.0029 0.0247 0.0431
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0021 0.0035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0021 0.0014
Schistosoma mansoni dishevelled 0.0016 0.007 0.0117
Onchocerca volvulus Alhambra homolog 0.002 0.0127 0.0281
Treponema pallidum fructose-bisphosphate aldolase 0.03 0.3989 1
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0419 0.074
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0029 0.0247 0.043
Loa Loa (eye worm) hypothetical protein 0.002 0.0127 0.0216
Giardia lamblia Hypothetical protein 0.0074 0.0866 0.2001
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0023 0.0163 0.0306
Schistosoma mansoni coup transcription factor 0.0012 0.0021 0.0035
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0011 0.0008 0.0001
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.003 0.027 0.0263
Mycobacterium ulcerans thymidine phosphorylase 0.0737 1 1
Echinococcus multilocularis Protein son of sevenless 0.0011 0.0008 0.0001
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.007 0.0113
Toxoplasma gondii phosphorylase family protein 0.0029 0.0247 0.0433
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.002 0.0127 0.0212
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0073 0.086 0.1646
Schistosoma mansoni hypothetical protein 0.0019 0.0115 0.0192
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0084 0.0138
Schistosoma mansoni smad 0.0011 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0034 0.0324 0.0568
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.006 0.0099
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0021 0.0024
Schistosoma mansoni methylthioadenosine phosphorylase 0.0029 0.0247 0.0412
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.003 0.027 0.0517
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0023 0.0163 0.0156
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.021 0.0364
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0021 0.0014
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0021 0.0035
Schistosoma mansoni purine nucleoside phosphorylase 0.0138 0.1758 0.2934
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0011 0.0007 0.0012
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0029 0.0247 0.0602
Loa Loa (eye worm) hypothetical protein 0.0041 0.0419 0.074
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0073 0.086 0.153
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0084 0.0138
Loa Loa (eye worm) DIX domain-containing protein 0.0016 0.007 0.0113
Mycobacterium ulcerans cystathionine beta-synthase 0.0023 0.0163 0.0079
Schistosoma mansoni dep domain containing protein 0.0016 0.007 0.0117
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0029 0.0247 0.0472
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0021 0.0014
Trypanosoma cruzi nucleobase transporter, putative 0.0013 0.0028 0.0041
Brugia malayi N-terminal motif family protein 0.0321 0.4272 0.7655
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0013 0.0028 0.0038
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0023 0.0163 0.0201
Schistosoma mansoni chloride channel protein 0.0023 0.0163 0.0272
Leishmania major hypothetical protein, conserved 0.0023 0.0163 0.0266
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0029 0.0247 0.0431
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.007 0.0063
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0021 0.0031
Echinococcus granulosus H:Cl exchange transporter 7 0.0023 0.0163 0.0156
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.018 0.2335 0.4418
Giardia lamblia PHD finger protein 15 0.002 0.0127 0.011
Schistosoma mansoni z-protein (S1r protein) 0.0016 0.007 0.0117
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0021 0.0014
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0011 0.0008 0.0013
Entamoeba histolytica hypothetical protein 0.007 0.0811 0.2018
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0029 0.0247 0.0472
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0073 0.086 0.1646
Echinococcus multilocularis purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0013 0.0028 0.0038
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0073 0.086 0.0853
Schistosoma mansoni alpha(13)fucosyltransferase 0.0034 0.0314 0.0525
Leishmania major eukaryotic translation initiation factor-like protein 0.0073 0.086 0.1646
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0019 0.0117 0.011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.3989 0.7147
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0074 0.0866 0.0859
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0115 0.0108
Loa Loa (eye worm) chloride channel 3 0.0023 0.0163 0.028
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0029 0.0247 0.043
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.03 0.3989 1
Onchocerca volvulus 0.0159 0.2044 0.4777
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.003 0.027 0.0478
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0023 0.0163 0.0079
Trypanosoma brucei GMP reductase 0.0379 0.508 1
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0023 0.0163 0.0306
Treponema pallidum pfs protein (pfs) 0.0029 0.0247 0.0417
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0357 0.4769 1
Leishmania major nucleoside phosphorylase-like protein 0.0029 0.0247 0.0433
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0021 0.0024
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0021 0.0024
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0029 0.0247 0.043
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0208 0.2717 0.2655
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.3989 0.7147
Echinococcus granulosus histone lysine methyltransferase setb 0.0021 0.0137 0.013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0163 0.028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0024
Schistosoma mansoni hypothetical protein 0.0152 0.1947 0.3249
Loa Loa (eye worm) hypothetical protein 0.0074 0.0866 0.1541
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0357 0.4769 0.4725
Onchocerca volvulus 0.0031 0.0284 0.0647
Brugia malayi alpha1,3-fucosyltransferase homologue 0.0199 0.2594 0.4644
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0021 0.0035
Schistosoma mansoni hypothetical protein 0.0252 0.3321 0.5542
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0017 0.0084 0.0193
Brugia malayi jmjC domain containing protein 0.0065 0.0752 0.1338
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0811 0.0804
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0138 0.1758 0.3143
Schistosoma mansoni hypothetical protein 0.0019 0.0115 0.0192
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0024
Schistosoma mansoni hypothetical protein 0.0019 0.0115 0.0192
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.003 0.027 0.0517
Schistosoma mansoni alpha(13)fucosyltransferase 0.0034 0.0314 0.0525
Leishmania major eukaryotic translation initiation factor-like 0.0073 0.086 0.1646
Loa Loa (eye worm) RasGEF domain-containing protein 0.0011 0.0008 0.0001
Brugia malayi chloride channel protein 7 0.0023 0.0163 0.028
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0863 0.1652
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0021 0.0014
Toxoplasma gondii CBS domain-containing protein 0.0023 0.0163 0.0266
Treponema pallidum Mg2+ transport protein (mgtE) 0.0023 0.0163 0.0201
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0074 0.0866 0.1541
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0073 0.086 0.1435
Brugia malayi Pre-SET motif family protein 0.0021 0.0137 0.0233
Entamoeba histolytica DNA repair and recombination protein, putative 0.003 0.027 0.0659
Entamoeba histolytica hypothetical protein 0.007 0.0811 0.2018
Brugia malayi RasGEF domain containing protein 0.0011 0.0008 0.0001
Trichomonas vaginalis set domain proteins, putative 0.0159 0.2044 0.3657
Loa Loa (eye worm) hypothetical protein 0.0051 0.0554 0.0982
Mycobacterium ulcerans transcriptional regulator 0.0023 0.0163 0.0079
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0021 0.0014
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0863 0.0785
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Schistosoma mansoni jumonji/arid domain-containing protein 0.0026 0.021 0.035
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0001
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0073 0.086 0.2141
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0024
Mycobacterium ulcerans hypothetical protein 0.0023 0.0163 0.0079
Brugia malayi ancient conserved domain protein 2 0.0023 0.0163 0.028
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0029 0.0247 0.0164
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0379 0.508 0.8476
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0011 0.0008 0.0001
Leishmania major CBS domain protein, conserved 0.0023 0.0163 0.0266
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Echinococcus granulosus alpha13fucosyltransferase 0.0084 0.1016 0.101
Loa Loa (eye worm) chloride channel protein 7 0.0023 0.0163 0.028
Echinococcus multilocularis ras GTP exchange factor 0.0011 0.0008 0.0001
Echinococcus multilocularis purine nucleoside phosphorylase 0.011 0.1363 0.1357
Schistosoma mansoni alpha(13)fucosyltransferase 0.0199 0.2594 0.4329
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0023 0.0163 0.0156
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0023 0.0163 0.0156
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.003 0.027 0.0517
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0074 0.0866 0.1541
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0137 0.0229
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0021 0.0024
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0113
Mycobacterium tuberculosis Conserved protein 0.0023 0.0163 0.0079
Brugia malayi N-terminal motif family protein 0.0011 0.0008 0.0001
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0379 0.508 0.5076
Giardia lamblia Fructose-bisphosphate aldolase 0.03 0.3989 1
Schistosoma mansoni hypothetical protein 0.003 0.027 0.0451
Mycobacterium tuberculosis Conserved protein 0.0023 0.0163 0.0079
Onchocerca volvulus 0.0023 0.0163 0.0364
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.1873 0.1804
Trypanosoma cruzi nucleobase transporter, putative 0.0013 0.0028 0.0041
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0001
Loa Loa (eye worm) glutaminase 2 0.0416 0.5578 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0017 0.0084 0.0077
Schistosoma mansoni smad1 5 8 and 0.0011 0.0007 0.0012
Schistosoma mansoni hypothetical protein 0.007 0.0811 0.1353
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0029 0.0247 0.0417
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0061 0.069 0.0683
Echinococcus multilocularis purine nucleoside phosphorylase 0.011 0.1363 0.1357
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0021 0.0014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0777 0.1297
Entamoeba histolytica nucleoside transporter, putative 0.0074 0.0866 0.2155
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0682 0.1211
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0011 0.0008 0.0001
Toxoplasma gondii CBS domain-containing protein 0.0023 0.0163 0.0266
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0379 0.508 0.9105
Schistosoma mansoni smad1 5 8 and 0.0011 0.0007 0.0012
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0073 0.086 0.153
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0113
Echinococcus granulosus purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Trichomonas vaginalis glutaminase, putative 0.0416 0.5578 1
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.007 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0021 0.0024
Echinococcus granulosus Protein son of sevenless 0.0011 0.0008 0.0001
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0158 0.2025 0.3622
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0074 0.0866 0.1541
Trypanosoma cruzi nucleoside transporter-like, putative 0.0013 0.0028 0.0041
Echinococcus granulosus uridine phosphorylase 1 0.0029 0.0247 0.024
Trypanosoma cruzi GMP reductase 0.0379 0.508 1
Schistosoma mansoni equilibrative nucleoside transporter 0.0013 0.0028 0.0048
Schistosoma mansoni hypothetical protein 0.0252 0.3321 0.5542
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0199 0.2597 0.2534
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0023 0.0163 0.0157
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0023 0.0163 0.0157
Toxoplasma gondii CBS family protein 0.0023 0.0163 0.0266
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0152 0.1947 0.1941
Leishmania major inosine-5-monophosphate dehydrogenase 0.0379 0.508 1
Trypanosoma cruzi GMP reductase 0.0379 0.508 1
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0021 0.0035
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0021 0.0035
Plasmodium falciparum purine nucleoside phosphorylase 0.0029 0.0247 0.0348
Trypanosoma cruzi chloride channel protein, putative 0.0023 0.0163 0.0306
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0357 0.4769 1
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0074 0.0866 0.2013
Echinococcus multilocularis dnaJ subfamily B 0.0446 0.5993 0.599
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0016 0.007 0.0117
Giardia lamblia Hypothetical protein 0.0023 0.0163 0.0201
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0021 0.0031
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0021 0.0024
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.007 0.0063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.3989 0.7147
Brugia malayi hypothetical protein 0.0016 0.007 0.0113
Brugia malayi regulator of G-protein signaling egl-10 0.0016 0.007 0.0113
Mycobacterium tuberculosis Conserved protein 0.0023 0.0163 0.0079
Brugia malayi hypothetical protein 0.0013 0.0028 0.0038
Schistosoma mansoni protein kinase subunit gamma 0.0023 0.0163 0.0272
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0017 0.0084 0.0139
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0029 0.0247 0.0417
Mycobacterium ulcerans glutaminase 0.0416 0.5578 0.554
Brugia malayi DIX domain containing protein 0.0016 0.007 0.0113
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0115 0.0194
Echinococcus granulosus equilibrative nucleoside transporter 0.0074 0.0866 0.0859
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0023 0.0163 0.0079
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0021 0.0024
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0023 0.0163 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0021 0.0024
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0379 0.508 1
Brugia malayi RasGEF domain containing protein 0.0011 0.0008 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0811 0.1353
Loa Loa (eye worm) hypothetical protein 0.0084 0.1016 0.1812
Echinococcus multilocularis peregrin 0.002 0.0127 0.012
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0016 0.007 0.0146
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0138 0.1758 0.3142
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0863 0.0785
Brugia malayi jmjC domain containing protein 0.0026 0.021 0.0364
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0021 0.0014
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0029 0.0247 0.0433
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0021 0.0014
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0073 0.086 0.153
Brugia malayi N-terminal motif family protein 0.0011 0.0008 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0137 0.0233
Mycobacterium ulcerans hypothetical protein 0.0023 0.0163 0.0079
Schistosoma mansoni chloride channel protein 0.0023 0.0163 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0021 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0021 0.0024
Echinococcus multilocularis son of sevenless 1 0.0011 0.0008 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.2115 0.211
Entamoeba histolytica hypothetical protein 0.0029 0.0247 0.0602
Plasmodium falciparum protein MAM3, putative 0.0023 0.0163 0.0168
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0379 0.508 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0165 0.212 0.3794
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0379 0.508 1
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.007 0.0063
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.007 0.0063
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0038
Schistosoma mansoni jumonji domain containing protein 0.0052 0.0567 0.0947
Toxoplasma gondii IMP dehydrogenas 0.0379 0.508 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0682 0.1211
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0115 0.0194
Echinococcus granulosus Transcription initiation factor TFIID subunit 0.0051 0.0554 0.0548
Echinococcus granulosus Pleckstrin G protein interacting region 0.0016 0.007 0.0063
Loa Loa (eye worm) fucosyl transferase 0.0199 0.2594 0.4644
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0023 0.0163 0.0306
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0077 0.0912 0.1522
Trichomonas vaginalis conserved hypothetical protein 0.003 0.027 0.0471
Mycobacterium tuberculosis Hypothetical protein 0.0029 0.0247 0.0164
Loa Loa (eye worm) RasGEF domain-containing protein 0.0011 0.0008 0.0001
Trypanosoma cruzi chloride channel protein, putative 0.0023 0.0163 0.0306
Loa Loa (eye worm) hypothetical protein 0.0019 0.0115 0.0194
Mycobacterium ulcerans hypothetical protein 0.0023 0.0163 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0021 0.0024
Trypanosoma cruzi nucleoside transporter 1, putative 0.0013 0.0028 0.0041
Echinococcus granulosus lysine specific demethylase 5A 0.0026 0.021 0.0203
Echinococcus multilocularis purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0138 0.1758 0.1688
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.007 0.0113
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0021 0.0014
Mycobacterium tuberculosis Conserved hypothetical protein 0.0029 0.0247 0.0164
Onchocerca volvulus 0.0016 0.007 0.0146
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0011 0.0008 0.0013
Echinococcus granulosus purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Schistosoma mansoni glutaminase 0.0416 0.5578 0.9308
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0021 0.0024
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0679 0.1289
Loa Loa (eye worm) hypothetical protein 0.0023 0.0163 0.028
Schistosoma mansoni hypothetical protein 0.0041 0.0419 0.07
Loa Loa (eye worm) loechrig isoform VII 0.0023 0.0163 0.028
Schistosoma mansoni thyroid hormone receptor 0.0164 0.2115 0.353
Brugia malayi glutaminase DH11.1 0.0416 0.5578 1
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0011 0.0008 0.0013
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0208 0.2717 0.2655
Loa Loa (eye worm) hypothetical protein 0.011 0.1363 0.2435
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0021 0.0024
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0011 0.0008 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0021 0.0024
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0029 0.0247 0.0602
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0379 0.508 0.5076
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0863 0.1652
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0023 0.0163 0.0156
Schistosoma mansoni smad1 5 8 and 0.0011 0.0007 0.0012
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0199 0.2597 0.4951
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.3989 0.7147
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0113
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0682 0.1211
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0247 0.043
Brugia malayi GMP reductase 0.0158 0.2025 0.3622
Leishmania major glycosyl transferase, putative 0.0034 0.0314 0.0566
Giardia lamblia Rrm3p helicase 0.003 0.027 0.0476
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0023 0.0163 0.0156
Trypanosoma cruzi chloride channel protein, putative 0.0023 0.0163 0.0306
Trypanosoma cruzi nucleoside transporter 1, putative 0.0013 0.0028 0.0041
Brugia malayi Fucosyl transferase family protein 0.0199 0.2594 0.4644
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0073 0.086 0.0853
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0023 0.0163 0.0079
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.007 0.0063
Echinococcus multilocularis cpg binding protein 0.0033 0.0308 0.0301
Entamoeba histolytica nucleoside transporter, putative 0.0013 0.0028 0.0053
Treponema pallidum hemolysin (tlyC) 0.0023 0.0163 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0024
Schistosoma mansoni uridine phosphorylase 0.0029 0.0247 0.0412
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.0084 0.0138
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0023 0.0163 0.0266
Loa Loa (eye worm) GMP reductase 0.0158 0.2025 0.3622
Schistosoma mansoni ap endonuclease 0.0017 0.0084 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0021 0.0024
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0023 0.0163 0.0079
Echinococcus granulosus purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Schistosoma mansoni jumonji/arid domain-containing protein 0.0026 0.021 0.035
Loa Loa (eye worm) transcription factor SMAD2 0.0165 0.212 0.3794
Onchocerca volvulus Putative GMP reductase 0.0158 0.2025 0.4731
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0029 0.0247 0.0417
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0017 0.0084 0.011
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0029 0.0247 0.0602
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0321 0.4272 1
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.003 0.027 0.0263
Echinococcus granulosus jumonji domain containing protein 0.0028 0.0235 0.0228
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0115 0.0108
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0137 0.0229
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0863 0.144
Brugia malayi hypothetical protein 0.0074 0.0866 0.1541
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0074 0.0866 0.1541
Onchocerca volvulus 0.0012 0.0021 0.0031
Brugia malayi translation initiation factor 4E 0.0073 0.086 0.1531
Loa Loa (eye worm) glutaminase 0.0416 0.5578 1
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0029 0.0247 0.043
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0752 0.0746
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0029 0.0247 0.043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0021 0.0024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0077 0.0912 0.1522
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0863 0.0785
Echinococcus granulosus purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.3989 0.7147
Giardia lamblia UPL-1 0.0029 0.0247 0.0417
Toxoplasma gondii hypothetical protein 0.0016 0.007 0.0082
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0029 0.0247 0.0472
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0029 0.0247 0.0602
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0073 0.086 0.168
Trypanosoma cruzi nucleoside transporter-like, putative 0.0013 0.0028 0.0041
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0021 0.0035
Schistosoma mansoni ap endonuclease 0.0017 0.0084 0.0141
Echinococcus granulosus dnaJ subfamily B 0.0446 0.5993 0.599
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0023 0.0163 0.0156
Echinococcus granulosus cpg binding protein 0.0033 0.0308 0.0301
Echinococcus multilocularis geminin 0.0252 0.3321 0.3316
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0138 0.1758 0.4287
Echinococcus multilocularis thymidine phosphorylase 0.0737 1 1
Loa Loa (eye worm) translation initiation factor 4E 0.0073 0.086 0.1531
Brugia malayi Nucleoside transporter family protein 0.0074 0.0866 0.1541
Schistosoma mansoni alpha(13)fucosyltransferase 0.0034 0.0314 0.0525
Schistosoma mansoni regulator of G protein signaling 0.0016 0.007 0.0117
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0021 0.0137 0.0215
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0074 0.0866 0.2013
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0023 0.0163 0.0266
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0023 0.0163 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0021 0.0024
Echinococcus granulosus son of sevenless 1 0.0011 0.0008 0.0001
Brugia malayi Voltage gated chloride channel family protein 0.0023 0.0163 0.028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0024
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.018 0.2335 0.227
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0013 0.0028 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0077 0.0912 0.0906
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.3989 0.7147
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0021 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0021 0.0137 0.0229
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.014 0.178 0.3182
Echinococcus multilocularis alpha(13)fucosyltransferase 0.0084 0.1016 0.101
Echinococcus granulosus purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Echinococcus granulosus purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0152 0.1947 0.1941
Brugia malayi RasGEF domain containing protein 0.0011 0.0008 0.0001
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0752 0.0746
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0863 0.0785
Echinococcus granulosus PHD finger protein rhinoceros 0.002 0.0127 0.012
Schistosoma mansoni alpha(13)fucosyltransferase 0.0034 0.0314 0.0525
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0021 0.0031
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0029 0.0247 0.0602
Schistosoma mansoni uridine phosphorylase 0.0029 0.0247 0.0412
Trypanosoma cruzi nucleobase transporter, putative 0.0013 0.0028 0.0041
Entamoeba histolytica nucleoside transporter, putative 0.0013 0.0028 0.0053
Schistosoma mansoni ras GTP exchange factor 0.0011 0.0008 0.0013
Brugia malayi loechrig isoform VII 0.0023 0.0163 0.028
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0023 0.0163 0.0079
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0029 0.0247 0.043
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0077 0.0912 0.1624
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0127 0.0196
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0021 0.0014
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0029 0.0247 0.0472
Mycobacterium leprae probable uridine phosphorylase 0.0029 0.0247 0.0171
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0138 0.1758 0.4105
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.003 0.027 0.0478
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0029 0.0247 0.0164
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.003 0.027 0.0478
Loa Loa (eye worm) hypothetical protein 0.0074 0.0866 0.1541
Schistosoma mansoni dishevelled 0.0016 0.007 0.0117
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0115 0.0108
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0077 0.0912 0.1522
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0021 0.0137 0.013
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0017 0.0084 0.0151
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0138 0.1758 0.3244
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0077 0.0912 0.0906
Trypanosoma brucei uridine phosphorylase 0.0029 0.0247 0.0433
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0029 0.0247 0.0348
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0074 0.0866 0.0859
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.007 0.0063
Toxoplasma gondii phosphorylase family protein 0.0029 0.0247 0.0433
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0021 0.0014
Brugia malayi MTAP 0.0029 0.0247 0.0431
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.3989 0.7147
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0017 0.0084 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0021 0.0024
Leishmania major chloride channel protein, putative 0.0023 0.0163 0.0266
Schistosoma mansoni hypothetical protein 0.002 0.0127 0.0212
Brugia malayi steroid hormone receptor 0.0012 0.0021 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0021 0.0024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0024
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0021 0.0024
Plasmodium vivax hypothetical protein, conserved 0.002 0.0127 0.0092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.3989 0.7147
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0024
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Schistosoma mansoni methylthioadenosine phosphorylase 0.0029 0.0247 0.0412
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0379 0.508 1
Schistosoma mansoni alpha(13)fucosyltransferase 0.0199 0.2594 0.4329
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0811 0.0804
Brugia malayi Bromodomain containing protein 0.002 0.0127 0.0216
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0021 0.0014
Schistosoma mansoni alpha(13)fucosyltransferase 0.0034 0.0314 0.0525
Loa Loa (eye worm) hypothetical protein 0.0199 0.2594 0.4644
Plasmodium falciparum phd finger protein, putative 0.002 0.0127 0.0092
Brugia malayi exodeoxyribonuclease III family protein 0.0017 0.0084 0.0139
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0379 0.508 0.5038
Trypanosoma cruzi chloride channel protein, putative 0.0023 0.0163 0.0306
Chlamydia trachomatis AMP nucleosidase 0.0029 0.0247 1
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0029 0.0247 0.024
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.011 0.1363 0.1357
Echinococcus multilocularis GPCR, family 2 0.0019 0.0115 0.0108
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0016 0.007 0.0063
Brugia malayi ecdysteroid receptor 0.0012 0.0021 0.0024
Brugia malayi hypothetical protein 0.007 0.0811 0.1443
Echinococcus granulosus methylthioadenosine phosphorylase 0.0029 0.0247 0.024
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.007 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0077 0.0912 0.0906
Schistosoma mansoni cpg binding protein 0.0031 0.0284 0.0473
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0013 0.0028 0.0038
Brugia malayi MH2 domain containing protein 0.0165 0.212 0.3794
Leishmania major chloride channel protein, putative 0.0023 0.0163 0.0266
Echinococcus granulosus geminin 0.0252 0.3321 0.3316
Schistosoma mansoni alpha(13)fucosyltransferase 0.0199 0.2594 0.4329
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.03 0.3989 1
Brugia malayi ancient conserved domain protein 4 0.0023 0.0163 0.028
Loa Loa (eye worm) hypothetical protein 0.006 0.0682 0.1211
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0017 0.0084 0.0151
Brugia malayi hypothetical protein 0.0016 0.007 0.0113
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0379 0.508 1
Brugia malayi CXXC zinc finger family protein 0.0031 0.0284 0.0496
Echinococcus multilocularis jumonji domain containing protein 0.0028 0.0235 0.0228
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0073 0.086 0.1646
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0314 0.0605
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0247 0.043
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0021 0.0014
Echinococcus multilocularis purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0021 0.0035
Loa Loa (eye worm) hypothetical protein 0.0012 0.0021 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0021 0.0024
Plasmodium vivax SET domain protein, putative 0.0021 0.0137 0.0113
Schistosoma mansoni hypothetical protein 0.0019 0.0115 0.0192
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0863 0.144
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0016 0.007 0.0113
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0158 0.2025 0.3622
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0208 0.2717 0.5194
Loa Loa (eye worm) IMP dehydrogenase 1 0.0379 0.508 0.9105
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0023 0.0163 0.0079
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0284 0.0496
Toxoplasma gondii Purine nucleoside phosphorylase 0.0029 0.0247 0.0433
Schistosoma mansoni alpha(13)fucosyltransferase 0.0034 0.0314 0.0525
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0023 0.0163 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0021 0.0024
Schistosoma mansoni hypothetical protein 0.0056 0.0629 0.1049
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0029 0.0247 0.0472
Toxoplasma gondii exonuclease III APE 0.0017 0.0084 0.011
Loa Loa (eye worm) RasGEF domain-containing protein 0.0011 0.0008 0.0001
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0023 0.0163 0.0157
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0029 0.0247 0.043
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0013 0.0028 0.0038
Entamoeba histolytica hypothetical protein, conserved 0.003 0.027 0.0659
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0023 0.0163 0.0156
Brugia malayi nuclear receptor NHR-88 0.0012 0.0021 0.0024
Brugia malayi PHD-finger family protein 0.002 0.0127 0.0216
Schistosoma mansoni alpha(13)fucosyltransferase 0.0199 0.2594 0.4329
Echinococcus granulosus peregrin 0.002 0.0127 0.012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0021 0.0035
Echinococcus granulosus purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Loa Loa (eye worm) hypothetical protein 0.0023 0.0163 0.028
Brugia malayi Pre-SET motif family protein 0.014 0.178 0.3182
Echinococcus multilocularis uridine phosphorylase 1 0.0029 0.0247 0.024
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0021 0.0035
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0029 0.0247 0.0602
Echinococcus granulosus H:Cl exchange transporter 4 0.0023 0.0163 0.0156
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0074 0.0866 0.0859
Schistosoma mansoni purine nucleoside phosphorylase 0.0138 0.1758 0.2934
Schistosoma mansoni Smad4 0.0011 0.0007 0.0012
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.1873 0.3479
Echinococcus multilocularis purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.0737 1 1
Echinococcus granulosus GPCR family 2 0.0019 0.0115 0.0108
Schistosoma mansoni thyroid hormone receptor 0.0164 0.2115 0.353
Loa Loa (eye worm) uridine phosphorylase 0.0029 0.0247 0.0431
Echinococcus multilocularis purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0021 0.0137 0.013
Echinococcus multilocularis PHD finger protein rhinoceros 0.002 0.0127 0.012
Echinococcus granulosus purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Schistosoma mansoni methylthioadenosine phosphorylase 0.0029 0.0247 0.0412
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0023 0.0163 0.0201
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0023 0.0163 0.0266
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0115 0.0194
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0023 0.0163 0.0156
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0115 0.0108
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.042 0.0741
Brugia malayi nuclear hormone receptor 0.0012 0.0021 0.0024
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0077 0.0912 0.1624
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0021 0.0014
Echinococcus multilocularis lysine specific demethylase 5A 0.0024 0.0185 0.0178
Leishmania major guanosine monophosphate reductase 0.0379 0.508 1
Brugia malayi CLC chloride channel protein 0.0023 0.0163 0.028
Echinococcus multilocularis Transcription initiation factor TFIID subunit 0.0051 0.0554 0.0548
Leishmania major methylthioadenosine phosphorylase, putative 0.0029 0.0247 0.0433
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0863 0.0856
Echinococcus granulosus ras GTP exchange factor 0.0011 0.0008 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0314 0.0605
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0138 0.1758 0.1688
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0017 0.0084 0.011
Echinococcus multilocularis purine nucleoside phosphorylase 0.0138 0.1758 0.1752
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0127 0.0216
Loa Loa (eye worm) hypothetical protein 0.0074 0.0866 0.1541
Echinococcus multilocularis alpha(13)fucosyltransferase 0.0084 0.1016 0.101
Schistosoma mansoni alpha 13/4 fucosyltransferase Lewis 1 0.0115 0.143 0.2387
Onchocerca volvulus 0.0021 0.0137 0.0304
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0021 0.0024
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0073 0.086 0.153
Entamoeba histolytica hypothetical protein 0.007 0.0811 0.2018
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.1873 0.1804
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0077 0.0912 0.0906
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0029 0.0247 0.0164
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0021 0.0014
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.003 0.027 0.0478
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0021 0.0035
Treponema pallidum uridine phosphorylase (udp) 0.0029 0.0247 0.0417
Brugia malayi CBS domain containing protein 0.0023 0.0163 0.028
Schistosoma mansoni hypothetical protein 0.0446 0.5993 1
Schistosoma mansoni alpha(13)fucosyltransferase 0.0034 0.0314 0.0525
Trypanosoma cruzi nucleoside transporter 1, putative 0.0013 0.0028 0.0041
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0379 0.508 0.5038
Schistosoma mansoni protein kinase 0.0013 0.0028 0.0048
Onchocerca volvulus Alpha 1,3 fucosyltransferase homolog 0.0084 0.1016 0.2366
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0023 0.0163 0.0201
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0084 0.1016 0.101
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0021 0.0137 0.0229
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0021 0.0024
Schistosoma mansoni chloride channel protein 0.0023 0.0163 0.0272
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0379 0.508 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0163 0.028
Schistosoma mansoni cpg binding protein 0.0033 0.0308 0.0514
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0127 0.0196
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0011 0.0008 0.0013
Entamoeba histolytica hypothetical protein 0.007 0.0811 0.2018
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0073 0.086 0.2141
Loa Loa (eye worm) hypothetical protein 0.0321 0.4272 0.7655
Schistosoma mansoni alpha(13)fucosyltransferase 0.0034 0.0314 0.0525
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0863 0.0856
Echinococcus granulosus H:Cl exchange transporter 3 0.0023 0.0163 0.0156
Schistosoma mansoni cpg binding protein 0.0033 0.0308 0.0514
Schistosoma mansoni alpha(13)fucosyltransferase 0.0199 0.2594 0.4329
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0023 0.0163 0.0272
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0073 0.086 0.168

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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