Detailed information for compound 20885

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 332.805 | Formula: C16H13ClN2O2S
  • H donors: 1 H acceptors: 3 LogP: 3.58 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cccc(c1)c1nc([nH]c1c1ccccc1)S(=O)(=O)C
  • InChi: 1S/C16H13ClN2O2S/c1-22(20,21)16-18-14(11-6-3-2-4-7-11)15(19-16)12-8-5-9-13(17)10-12/h2-10H,1H3,(H,18,19)
  • InChiKey: LWRWEAMTXVIDIA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0204 0.027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0274 0.3247 0.4285
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0016 0.0049 0.0073
Schistosoma mansoni ferritin light chain 0.0017 0.0059 0.0078
Echinococcus multilocularis protein patched 0.0042 0.0371 0.0371
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0049 0.0064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Trypanosoma cruzi cysteine peptidase, putative 0.0014 0.0028 0.0012
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0204 0.0204
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0486 0.1433
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0486 0.0486
Trypanosoma brucei cysteine peptidase C (CPC) 0.0096 0.1038 1
Onchocerca volvulus 0.0035 0.0285 0.052
Brugia malayi Cathepsin L-like precursor 0.0051 0.0486 0.0849
Entamoeba histolytica hypothetical protein 0.0109 0.1201 0.3486
Echinococcus granulosus cysteine protease 0.003 0.0226 0.0226
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0438 0.1226
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0085 0.0148
Brugia malayi G-protein coupled receptor 0.0029 0.0204 0.0356
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0065 0.0661 0.1156
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0016 0.0049 0.0448
Loa Loa (eye worm) hypothetical protein 0.0035 0.0285 0.0376
Entamoeba histolytica cysteine protease, putative 0.0051 0.0486 0.1368
Brugia malayi DKFZp564C0469 protein 0.002 0.0093 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0441 0.1604
Brugia malayi hypothetical protein 0.0109 0.1201 0.2098
Trypanosoma cruzi major cysteine proteinase, putative 0.0016 0.0049 0.0076
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0029 0.0204 0.0204
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0024 0.0116
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0.0028 0.0037
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0204 0.0204
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0055 0.0096
Entamoeba histolytica Ran family GTPase 0.0022 0.0123 0.0293
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0055 0.0302
Echinococcus multilocularis cathepsin b 0.0274 0.3247 0.3247
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0204 0.0269
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.2099 0.277
Onchocerca volvulus 0.0051 0.0486 0.0887
Entamoeba histolytica cysteine protease, putative 0.0016 0.0049 0.0073
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.1063 0.1063
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0093 0.0789
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0024 0.0042
Echinococcus granulosus g protein coupled receptor 0.0029 0.0204 0.0204
Mycobacterium ulcerans beta-lactamase 0.0035 0.0285 0.1671
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0024 0.0032
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0292 0.1715
Echinococcus multilocularis serotonin receptor 0.0029 0.0204 0.0204
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0052 0.0489 0.0489
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0055 0.0414
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0016 0.0049 0.0073
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni myosin xvIII 0.0029 0.0204 0.0269
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.2099 0.2099
Echinococcus granulosus hypothetical protein 0.0029 0.0204 0.0204
Schistosoma mansoni cathepsin S (C01 family) 0.0016 0.0049 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0055 0.0095
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0049 0.0089
Brugia malayi AKH receptor 0.0029 0.0204 0.0356
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.1584 1
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0486 0.1368
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0268 0.0937
Brugia malayi Bromodomain containing protein 0.0228 0.2679 0.4682
Echinococcus multilocularis fetal alzheimer antigen, falz 0.007 0.0715 0.0715
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0123 0.0221
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0204 0.0269
Entamoeba histolytica cysteine protease, putative 0.0016 0.0049 0.0073
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus multilocularis protein dispatched 1 0.0048 0.0445 0.0445
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0079 0.017
Trypanosoma brucei unspecified product 0.0019 0.0085 0.0708
Echinococcus multilocularis somatostatin receptor 0.0029 0.0204 0.0204
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0085 0.0708
Brugia malayi fibroinase precursor 0.0016 0.0049 0.0085
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0085 0.018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0055 0.0055
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0109 0.1196 0.1196
Onchocerca volvulus 0.0029 0.0204 0.0372
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0029 0.0204 0.0372
Schistosoma mansoni hypothetical protein 0.0109 0.1201 0.1584
Schistosoma mansoni apoferritin-2 0.0017 0.0059 0.0078
Onchocerca volvulus Neuropeptide F receptor homolog 0.0029 0.0204 0.0372
Schistosoma mansoni histamine h1 receptor 0.0029 0.0204 0.0269
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0285 0.0498
Leishmania major DNA polymerase kappa, putative 0.0019 0.0085 0.0599
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0085 0.0112
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0016 0.0049 0.0064
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0631 0.0832
Loa Loa (eye worm) hypothetical protein 0.002 0.0093 0.0123
Schistosoma mansoni zinc finger protein 0.0061 0.0604 0.0797
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0441 0.2671
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Brugia malayi Papain family cysteine protease containing protein 0.003 0.0226 0.0395
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0441 0.2671
Brugia malayi beta-lactamase 0.0035 0.0285 0.0498
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0204 0.0204
Echinococcus granulosus replication factor c subunit 1 0.002 0.0093 0.0093
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.0497 0.0497
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0226 0.0598
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Plasmodium falciparum serine repeat antigen 3 0.0016 0.0049 0.0448
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0049 0.0073
Echinococcus granulosus zinc finger protein 0.0061 0.0604 0.0604
Onchocerca volvulus 0.0051 0.0486 0.0887
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0204 0.0204
Entamoeba histolytica hypothetical protein 0.0109 0.1201 0.3486
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0169 0.1942 0.3395
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Mycobacterium tuberculosis Conserved protein 0.0035 0.0285 0.1003
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0055 0.0072
Schistosoma mansoni hypothetical protein 0.0041 0.0352 0.0465
Plasmodium falciparum serine repeat antigen 9 0.0016 0.0049 0.0448
Plasmodium vivax vivapain-2 0.0051 0.0486 0.8386
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.2099 0.277
Loa Loa (eye worm) hypothetical protein 0.002 0.0093 0.0123
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0085 0.018
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.1067 0.1408
Onchocerca volvulus 0.0029 0.0204 0.0372
Loa Loa (eye worm) hypothetical protein 0.0474 0.5721 0.755
Leishmania major cathepsin L-like protease 0.0051 0.0486 0.4555
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0109 0.1196 0.1196
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.1584 0.6004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0486 0.0641
Schistosoma mansoni neuropeptide receptor 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0037 0.0309 0.0407
Schistosoma mansoni zinc finger protein 0.0046 0.0424 0.0559
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0093 0.0681
Leishmania major cathepsin L-like protease 0.0051 0.0486 0.4555
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0204 0.0204
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0226 0.0298
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0204 0.0204
Mycobacterium tuberculosis Conserved protein 0.0035 0.0285 0.1003
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0204 0.0204
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0204 0.0204
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0059 0.0134
Echinococcus granulosus neuropeptide receptor 0.0029 0.0204 0.0204
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0093 0.0681
Loa Loa (eye worm) hypothetical protein 0.0116 0.1287 0.1699
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0079 0.0994
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0016 0.0049 0.0085
Schistosoma mansoni ferritin 0.0017 0.0059 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0093 0.0123
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0575 0.0575
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0079 0.0104
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0093 0.0204
Loa Loa (eye worm) hypothetical protein 0.0454 0.5476 0.7226
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0285 0.1003
Schistosoma mansoni hypothetical protein 0.0065 0.0661 0.0873
Echinococcus multilocularis muscleblind protein 0.015 0.1705 0.1705
Plasmodium falciparum serine repeat antigen 1 0.0016 0.0049 0.0448
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0486 0.0887
Echinococcus granulosus cathepsin b 0.0274 0.3247 0.3247
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0441 0.2671
Plasmodium falciparum serine repeat antigen 8 0.0016 0.0049 0.0448
Echinococcus granulosus geminin 0.0505 0.6104 0.6104
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus multilocularis GPCR, family 2 0.0031 0.0236 0.0236
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.1201 0.1201
Echinococcus multilocularis muscleblind protein 1 0.015 0.1705 0.1705
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.1063 0.1858
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.2099 0.2099
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0096 0.1038 0.3004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Brugia malayi hypothetical protein 0.002 0.0093 0.0163
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0204 0.0269
Loa Loa (eye worm) fibroinase 0.0051 0.0486 0.0641
Brugia malayi RE15519p 0.0029 0.0204 0.0356
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.3399 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0016 0.0049 0.0073
Loa Loa (eye worm) hypothetical protein 0.0163 0.1873 0.2472
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0093 0.0204
Loa Loa (eye worm) hypothetical protein 0.0058 0.0575 0.0758
Onchocerca volvulus 0.0029 0.0204 0.0372
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0204 0.0269
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0204 0.0269
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0016 0.0049 0.0448
Leishmania major GTP-binding protein, putative 0.0022 0.0123 0.0974
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0042 0.0371 0.049
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0631 0.0832
Schistosoma mansoni survival motor neuron protein 0.0097 0.1048 0.1383
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0441 0.077
Onchocerca volvulus 0.0014 0.0024 0.0044
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0059 0.0223
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni ferritin 0.0017 0.0059 0.0078
Trichomonas vaginalis ferritin, putative 0.0017 0.0059 0.0103
Brugia malayi RNA, U transporter 1 0.0166 0.1909 0.3337
Schistosoma mansoni hypothetical protein 0.0505 0.6104 0.8055
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Mycobacterium ulcerans hypothetical protein 0.0035 0.0285 0.1671
Loa Loa (eye worm) ctsf protein 0.0051 0.0486 0.0641
Brugia malayi RNA binding protein 0.0063 0.0631 0.1103
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0123 0.0974
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0204 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0371 0.1028
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0049 0.0073
Brugia malayi hypothetical protein 0.0454 0.5476 0.9571
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0486 0.0641
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0486 0.0641
Trypanosoma cruzi cysteine proteinase, putative 0.003 0.0226 0.0626
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0093 0.0204
Entamoeba histolytica hypothetical protein 0.0109 0.1201 0.3486
Schistosoma mansoni DNA ligase IV 0.002 0.0093 0.0123
Brugia malayi Bromodomain containing protein 0.0116 0.1285 0.2245
Schistosoma mansoni ran 0.0022 0.0123 0.0162
Onchocerca volvulus 0.0014 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0052 0.0497 0.0656
Onchocerca volvulus 0.0029 0.0204 0.0372
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0204 0.0356
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Onchocerca volvulus 0.0029 0.0204 0.0372
Brugia malayi CXXC zinc finger family protein 0.0029 0.0204 0.0357
Brugia malayi neuropeptide F receptor 0.0029 0.0204 0.0356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Onchocerca volvulus 0.0097 0.1048 0.1914
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0049 0.0073
Loa Loa (eye worm) hypothetical protein 0.0036 0.0292 0.0385
Onchocerca volvulus 0.0029 0.0204 0.0372
Brugia malayi Cathepsin L-like precursor 0.0037 0.0309 0.0539
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0182 0.2106 0.2106
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0024 0.0024
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0055 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0049 0.0073
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0204 0.0204
Toxoplasma gondii cathepsin B 0.0096 0.1038 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0014 0.0028 0.0049
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0226 0.0298
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0486 0.0486
Schistosoma mansoni cathepsin B (C01 family) 0.0016 0.0049 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.3399 1
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0065 0.0661 0.0661
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0049 0.0064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0274 0.3247 0.4285
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0285 0.0376
Brugia malayi cathepsin Z-like cysteine proteinase 0.0016 0.0049 0.0085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0037
Schistosoma mansoni hypothetical protein 0.0031 0.0236 0.0311
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0055 0.0055
Leishmania major cathepsin L-like protease 0.0051 0.0486 0.4555
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0204 0.0269
Plasmodium falciparum serine repeat antigen 5 0.0016 0.0049 0.0448
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0486 0.0486
Schistosoma mansoni ferritin light chain 0.0017 0.0059 0.0078
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0079 0.054
Echinococcus granulosus tar DNA binding protein 0.0063 0.0631 0.0631
Schistosoma mansoni topbp1 0.002 0.0093 0.0123
Schistosoma mansoni importin beta-1 0.0058 0.0575 0.0758
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0085 0.0112
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0024 0.0042
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0085 0.0708
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0049 0.0073
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0016 0.0049 0.0448
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0268 0.0937
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0016 0.0049 0.0448
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.002 0.0093 0.0123
Onchocerca volvulus 0.0014 0.0024 0.0044
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0079 0.0162
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0204 0.0269
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0065 0.0661 0.0661
Leishmania major cathepsin L-like protease 0.0051 0.0486 0.4555
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0486 0.0641
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.2099 0.2099
Leishmania major cathepsin L-like protease 0.0051 0.0486 0.4555
Brugia malayi beta-lactamase family protein 0.0035 0.0285 0.0498
Loa Loa (eye worm) hypothetical protein 0.0035 0.0285 0.0376
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Mycobacterium ulcerans lipase LipD 0.0035 0.0285 0.1671
Onchocerca volvulus 0.0029 0.0204 0.0372
Brugia malayi Serotonin receptor 0.0029 0.0204 0.0356
Brugia malayi Melatonin receptor type 1A 0.0029 0.0204 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0016 0.0049 0.0073
Schistosoma mansoni bromodomain containing protein 0.0015 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.0098 0.1067 0.1408
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0226 0.0598
Echinococcus multilocularis neuropeptide s receptor 0.0029 0.0204 0.0204
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0274 0.3247 0.4285
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0085 0.0188
Echinococcus multilocularis expressed protein 0.0017 0.0059 0.0059
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.1583 0.1583
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0123 0.1794
Leishmania major hypothetical protein, conserved 0.0046 0.0424 0.3941
Brugia malayi isocitrate dehydrogenase 0.0016 0.0055 0.0096
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0059 0.0223
Loa Loa (eye worm) hypothetical protein 0.0169 0.1942 0.2563
Echinococcus granulosus dna polymerase kappa 0.0019 0.0085 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0226 0.2084
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0236 0.0236
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0085 0.018
Echinococcus granulosus allatostatin A receptor 0.0029 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0064
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0093 0.0204
Onchocerca volvulus 0.0454 0.5476 1
Schistosoma mansoni hypothetical protein 0.0065 0.0661 0.0873
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0486 0.0887
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0049 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3399 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Echinococcus multilocularis sex peptide receptor 0.0029 0.0204 0.0204
Schistosoma mansoni cathepsin s 0.0014 0.0028 0.0037
Trypanosoma cruzi cysteine proteinase, putative 0.003 0.0226 0.0626
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0631 0.0832
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0204 0.0269
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0037 0.0309 0.0883
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0204 0.0269
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0079 0.009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0079 0.0079
Echinococcus granulosus snurportin 1 0.0624 0.7578 0.7578
Brugia malayi ORL1-like opioid receptor 0.0029 0.0204 0.0356
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni amine GPCR 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0274 0.3247 0.4285
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0441 0.077
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0682 0.1192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3399 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0309 0.0407
Echinococcus multilocularis cathepsin L 0.003 0.0226 0.0226
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Loa Loa (eye worm) hypothetical protein 0.015 0.1705 0.2249
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0204 0.0204
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.1067 0.1864
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0079 0.0162
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0309 0.0407
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni biogenic amine receptor 0.0029 0.0204 0.0269
Schistosoma mansoni hypothetical protein 0.0041 0.0352 0.0465
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0016 0.0049 0.0448
Schistosoma mansoni hypothetical protein 0.0029 0.0204 0.0269
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0226 0.0598
Loa Loa (eye worm) hypothetical protein 0.002 0.0093 0.0123
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.1082 0.1428
Plasmodium falciparum serine repeat antigen 7 0.0016 0.0049 0.0448
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0486 0.0486
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0085 0.0085
Brugia malayi Importin beta-1 subunit 0.0058 0.0575 0.1004
Entamoeba histolytica cysteine proteinase 2 0.003 0.0226 0.0598
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus granulosus methyl CpG binding domain protein 2 0.0052 0.0489 0.0489
Loa Loa (eye worm) hypothetical protein 0.0048 0.0441 0.0582
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0204 0.0269
Echinococcus multilocularis cathepsin b 0.0274 0.3247 0.3247
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0371 0.0371
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0093 0.0163
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0204 0.0204
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0024 0.0116
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0441 0.2671
Brugia malayi topoisomerase 0.002 0.0093 0.0163
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0085 0.0188
Schistosoma mansoni hypothetical protein 0.0067 0.0682 0.09
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0055 0.0072
Loa Loa (eye worm) hypothetical protein 0.002 0.0093 0.0123
Schistosoma mansoni cpg binding protein 0.0029 0.0204 0.027
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0016 0.0049 0.0448
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0064
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0226 0.0626
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Brugia malayi beta-lactamase family protein 0.0035 0.0285 0.0498
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0093 0.0093
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0486 0.0887
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0285 0.0376
Brugia malayi hypothetical protein 0.0474 0.5721 1
Brugia malayi hypothetical protein 0.002 0.0093 0.0163
Echinococcus multilocularis dna polymerase eta 0.0019 0.0085 0.0085
Plasmodium falciparum replication factor C subunit 1, putative 0.002 0.0093 0.1253
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.1201 0.1584
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.007 0.0715 0.0944
Entamoeba histolytica cysteine protease, putative 0.0016 0.0049 0.0073
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0049 0.0085
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0236 0.0412
Loa Loa (eye worm) hypothetical protein 0.0014 0.0028 0.0037
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0285 0.1671
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3399 1
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0204 0.0204
Plasmodium vivax unspecified product 0.0014 0.0028 0.0073
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0204 0.0204
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.2099 0.3669
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0285 0.0285
Schistosoma mansoni hypothetical protein 0.0031 0.0236 0.0311
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0268 0.0937
Trypanosoma brucei ISWI complex protein 0.0046 0.0424 0.4012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Plasmodium vivax importin-beta 2, putative 0.0058 0.0575 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0285 0.0376
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0079 0.0994
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0016 0.0049 0.0073
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0085 0.0234
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0285 0.0809
Onchocerca volvulus 0.0029 0.0204 0.0372
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0204 0.0204
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0049 0.0073
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0575 0.5484
Echinococcus multilocularis ferritin 0.0017 0.0059 0.0059
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.1201 0.1201
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0123 0.0307
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Loa Loa (eye worm) hypothetical protein 0.0031 0.0236 0.0311
Onchocerca volvulus 0.0016 0.0049 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Onchocerca volvulus 0.0037 0.0309 0.0564
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Brugia malayi sulfakinin receptor protein 0.0029 0.0204 0.0356
Echinococcus multilocularis nibrin 0.002 0.0093 0.0093
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0059 0.0134
Leishmania major hypothetical protein, conserved 0.0035 0.0285 0.2571
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0055 0.0556
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0204 0.0269
Echinococcus multilocularis snurportin 1 0.0624 0.7578 0.7578
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.002 0.0093 0.0442
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0285 0.1003
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0093 0.0204
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0204 0.0356
Brugia malayi cathepsin L precursor 0.0016 0.0049 0.0085
Loa Loa (eye worm) hypothetical protein 0.0036 0.0292 0.0385
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0236 0.0311
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0096 0.1038 0.3146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.003 0.0226 0.2084
Brugia malayi Papain family cysteine protease containing protein 0.003 0.0226 0.0395
Loa Loa (eye worm) hypothetical protein 0.0131 0.1468 0.1937
Schistosoma mansoni opsin-like receptor 0.0029 0.0204 0.0269
Onchocerca volvulus 0.0051 0.0486 0.0887
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0285 0.4733
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0371 0.0371
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0096 0.1038 0.137
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0085 0.0389
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0309 0.0843
Schistosoma mansoni amine GPCR 0.0029 0.0204 0.0269
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0631 0.0832
Loa Loa (eye worm) hypothetical protein 0.0214 0.2498 0.3297
Trypanosoma cruzi ISWI complex protein 0.0046 0.0424 0.124
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0079 0.065
Brugia malayi GnHR receptor homolog 0.0029 0.0204 0.0356
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0441 0.1235
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0204 0.0204
Echinococcus granulosus cathepsin l1 0.0051 0.0486 0.0486
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0204 0.0356
Plasmodium falciparum serine repeat antigen 6 0.0016 0.0049 0.0448
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0486 0.1368
Onchocerca volvulus 0.0029 0.0204 0.0372
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0055 0.0302
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0064
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0204 0.0356
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0079 0.0211
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0024 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0093 0.0204
Brugia malayi G-protein coupled receptor 0.0029 0.0204 0.0356
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0285 0.0772
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0441 0.2671
Brugia malayi Dopamine receptor protein 1 0.0029 0.0204 0.0356
Entamoeba histolytica cysteine protease, putative 0.0016 0.0049 0.0073
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0055 0.0414
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0441 0.411
Onchocerca volvulus 0.0035 0.0285 0.052
Trypanosoma cruzi ISWI complex protein 0.0046 0.0424 0.124
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0204 0.0269
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.1584 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0204 0.0204
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0049 0.0064
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0268 0.0937
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0085 0.0234
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0065 0.0661 0.0873
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.015 0.1705 0.2249
Giardia lamblia Cathepsin B precursor 0.0096 0.1038 0.2953
Trichomonas vaginalis ran, putative 0.0022 0.0123 0.0293
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.1048 0.1832
Schistosoma mansoni bromodomain containing protein 0.0193 0.224 0.2956
Loa Loa (eye worm) hypothetical protein 0.0123 0.1376 0.1816
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Schistosoma mansoni neuropeptide receptor 0.0029 0.0204 0.0269
Echinococcus granulosus expressed protein 0.0017 0.0059 0.0059
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0274 0.3247 0.4285
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0486 0.0486
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0486 0.8386
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0064
Leishmania major cathepsin L-like protease 0.0051 0.0486 0.4555
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0204 0.0204
Leishmania major cathepsin L-like protease 0.0051 0.0486 0.4555
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0441 0.2671
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0016 0.0049 0.0448
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.1067 0.1864
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0497 0.0656
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0204 0.0204
Echinococcus multilocularis survival motor neuron protein 1 0.0474 0.5721 0.5721
Brugia malayi cathepsin B-like cysteine proteinase 0.0274 0.3247 0.5675
Giardia lamblia Cathepsin B precursor 0.0096 0.1038 0.2953
Plasmodium falciparum cysteine proteinase falcipain 1 0.003 0.0226 0.3666
Brugia malayi follicle stimulating hormone receptor 0.0029 0.0204 0.0356
Plasmodium vivax unspecified product 0.0016 0.0049 0.0448
Schistosoma mansoni ap endonuclease 0.0018 0.0079 0.0104
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0016 0.0049 0.0448
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0204 0.0204
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0016 0.0049 0.0448
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0441 0.2671
Loa Loa (eye worm) hypothetical protein 0.0035 0.0285 0.0376
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0204 0.0204
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Toxoplasma gondii cathepsin CPL 0.0051 0.0486 0.4555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0226 0.0598
Echinococcus granulosus g protein coupled receptor 0.0029 0.0204 0.0204
Loa Loa (eye worm) apoptosis regulator protein 0.0065 0.0661 0.0873
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0631 0.0832
Trypanosoma cruzi cruzipain precursor, putative 0.0014 0.0028 0.0012
Loa Loa (eye worm) oxidoreductase 0.0014 0.0024 0.0032
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0486 0.4555
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0204 0.0269
Brugia malayi larval opioid receptor 0.0029 0.0204 0.0356
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0049 0.0064
Brugia malayi Cathepsin L-like precursor 0.0051 0.0486 0.0849
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.003 0.0226 0.0626
Echinococcus granulosus somatostatin receptor 0.0029 0.0204 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Plasmodium vivax serine-repeat antigen (SERA) 0.0016 0.0049 0.0448
Trypanosoma cruzi major cysteine proteinase, putative 0.0016 0.0049 0.0076
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0055 0.0556
Brugia malayi Cathepsin L-like precursor 0.0051 0.0486 0.0849
Echinococcus granulosus tachykinin peptides receptor 99D 0.0029 0.0204 0.0204
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.082 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0806 0.9835 0.9835
Schistosoma mansoni cpg binding protein 0.0036 0.0296 0.039
Onchocerca volvulus 0.0029 0.0204 0.0372
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0438 0.1226
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0292 1
Schistosoma mansoni ferritin 0.0017 0.0059 0.0078
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0123 0.1079
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0631 0.0832
Brugia malayi Cathepsin L-like precursor 0.0051 0.0486 0.0849
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0204 0.0204
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0236 0.0236
Trypanosoma cruzi cruzipain precursor, putative 0.0051 0.0486 0.1433
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0016 0.0049 0.0064
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.06 0.0792
Loa Loa (eye worm) hypothetical protein 0.0015 0.0031 0.0041
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0204 0.0269
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0085 0.0708
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0204 0.0204
Schistosoma mansoni apoptosis regulator bax 0.0065 0.0661 0.0873
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Echinococcus multilocularis zinc finger protein 0.0061 0.0604 0.0604
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0204 0.0204
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3399 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0204 0.0269
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0204 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0085 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0016 0.0049 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0049 0.0073
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0486 0.0486
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.3399 1
Toxoplasma gondii cathepsin CPC2 0.0016 0.0049 0.0243
Schistosoma mansoni ap endonuclease 0.0018 0.0079 0.0104
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0204 0.0204
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0292 0.103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0093 0.1253
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0489 0.0646
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0049 0.0085
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0079 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3399 1
Brugia malayi G protein-coupled receptor 0.0029 0.0204 0.0356
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0016 0.0049 0.0073
Schistosoma mansoni cathepsin C 0.0016 0.0049 0.0064
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0204 0.0269
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0441 0.1235
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0024 0.0042
Brugia malayi Cathepsin L-like precursor 0.0051 0.0486 0.0849
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0079 0.0351
Echinococcus multilocularis cathepsin L 0.0016 0.0049 0.0049
Onchocerca volvulus 0.0051 0.0486 0.0887
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0285 0.0809
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0096 0.1038 1
Toxoplasma gondii exonuclease III APE 0.0018 0.0079 0.054
Loa Loa (eye worm) cathepsin B 0.0096 0.1038 0.137
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0441 0.2671
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0016 0.0049 0.0064
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0016 0.0049 0.0448
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0285 0.1003
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0226 0.0298
Onchocerca volvulus 0.0051 0.0486 0.0887
Brugia malayi neuropeptide F receptor 0.0029 0.0204 0.0356
Leishmania major importin beta-1 subunit, putative 0.0047 0.0438 0.4081
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0204 0.0204
Echinococcus granulosus serotonin receptor 0.0029 0.0204 0.0204
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0029 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0049 0.0073
Echinococcus granulosus fetal alzheimer antigen falz 0.007 0.0715 0.0715
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0441 0.077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Brugia malayi Dopamine receptor 0.0029 0.0204 0.0356
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0575 0.5431
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0204 0.0269
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0274 0.3247 1
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0093 0.0214
Brugia malayi putative neuropeptide receptor 0.0029 0.0204 0.0356
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0441 0.1235
Echinococcus granulosus cpg binding protein 0.0036 0.0296 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0016 0.0049 0.0073
Brugia malayi Cathepsin L-like precursor 0.0051 0.0486 0.0849
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Giardia lamblia DINP protein human, muc B family 0.0019 0.0085 0.0108
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0093 0.0204
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0029 0.0204 0.0204
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0016 0.0049 0.0448
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0016 0.0049 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0438 0.1226
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Loa Loa (eye worm) hypothetical protein 0.0067 0.0682 0.09
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0036 0.0292 0.0385
Loa Loa (eye worm) PHD-finger family protein 0.0062 0.0623 0.0823
Mycobacterium leprae Probable lipase LipE 0.0035 0.0285 0.1671
Echinococcus granulosus muscleblind protein 0.015 0.1705 0.1705
Echinococcus granulosus dna polymerase eta 0.0019 0.0085 0.0085
Schistosoma mansoni neuropeptide receptor 0.0029 0.0204 0.0269
Brugia malayi TAR-binding protein 0.0063 0.0631 0.1103
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0085 0.0112
Schistosoma mansoni hypothetical protein 0.0505 0.6104 0.8055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Onchocerca volvulus 0.0029 0.0204 0.0372
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0123 0.0215
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0064
Onchocerca volvulus 0.0029 0.0204 0.0372
Echinococcus multilocularis geminin 0.0505 0.6104 0.6104
Giardia lamblia Replication factor C, subunit 1 0.002 0.0093 0.0132
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0016 0.0049 0.0064
Loa Loa (eye worm) bromodomain containing protein 0.0053 0.0512 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0309 0.0843
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0371 0.049
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0049 0.0085
Onchocerca volvulus 0.0029 0.0204 0.0372
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0292 0.4859
Leishmania major cathepsin L-like protease 0.0051 0.0486 0.4555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0204 0.0204
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0486 0.0641
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0486 0.1368
Loa Loa (eye worm) hypothetical protein 0.0036 0.0292 0.0385
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0486 0.0849
Echinococcus multilocularis cysteine protease 0.0051 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0035 0.0285 0.0376
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Brugia malayi Muscleblind-like protein 0.015 0.1705 0.2979
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0085 0.0708
Onchocerca volvulus 0.0014 0.0024 0.0044
Onchocerca volvulus 0.0029 0.0204 0.0372
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0024 0.0042
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0236 0.0236
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0204 0.0204
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0486 0.1433
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0049 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0049 0.0073
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0204 0.0269
Echinococcus multilocularis serotonin receptor 0.0029 0.0204 0.0204
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0204 0.0204
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0285 0.1003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.2099 0.277
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0609 0.5769
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.3399 1
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0093 0.0214
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0226 0.0598
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0204 0.0356
Onchocerca volvulus 0.0029 0.0204 0.0373
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0204 0.0269
Brugia malayi Cathepsin L-like cysteine proteinase 0.0037 0.0309 0.0539
Plasmodium vivax vivapain-3 0.003 0.0226 0.3666
Echinococcus granulosus neuropeptide s receptor 0.0029 0.0204 0.0204
Mycobacterium ulcerans hypothetical protein 0.0048 0.0441 0.2671
Schistosoma mansoni hypothetical protein 0.0624 0.7578 1
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0285 0.1003
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0285 0.2657
Entamoeba histolytica hypothetical protein 0.0109 0.1201 0.3486
Echinococcus granulosus cathepsin l1 0.0037 0.0309 0.0309
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0204 0.0204
Schistosoma mansoni amine GPCR 0.0029 0.0204 0.0269
Onchocerca volvulus 0.0035 0.0285 0.052
Onchocerca volvulus 0.0029 0.0204 0.0372
Echinococcus granulosus g protein coupled receptor 0.0029 0.0204 0.0204
Schistosoma mansoni patched 1 0.0042 0.0371 0.049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0204 0.0204
Entamoeba histolytica hypothetical protein 0.0016 0.0049 0.0073
Echinococcus granulosus neuropeptide receptor A26 0.0029 0.0204 0.0204
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0093 0.0123
Schistosoma mansoni cpg binding protein 0.0036 0.0296 0.039
Schistosoma mansoni hypothetical protein 0.0029 0.0204 0.0269
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0486 0.1433
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Trichomonas vaginalis esterase, putative 0.0035 0.0285 0.0772
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0441 0.411
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0055 0.0095
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0236 0.0412
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0204 0.0204
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0204 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0093 0.0204
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0204 0.0269
Brugia malayi Dopamine receptor protein 2 0.0029 0.0204 0.0356
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0285 0.0772
Schistosoma mansoni hypothetical protein 0.0097 0.1048 0.1383
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0032
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0204 0.0356
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0093 0.0163
Trypanosoma cruzi cysteine protease, putative 0.003 0.0226 0.0626
Echinococcus granulosus cathepsin L 0.0016 0.0049 0.0049
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0204 0.0204
Plasmodium vivax vivapain-1 0.003 0.0226 0.3666
Brugia malayi CHE-14 protein 0.0042 0.0371 0.0649
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0285 0.0772
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0204 0.0204
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0204 0.0269
Schistosoma mansoni hypothetical protein 0.0041 0.0352 0.0465
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3399 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus granulosus fmrfamide receptor 0.0029 0.0204 0.0204
Brugia malayi cathepsin Z-like cysteine proteinase 0.0016 0.0049 0.0085
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0497 0.0656
Brugia malayi Cathepsin L-like precursor 0.0014 0.0028 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0486 0.1368
Schistosoma mansoni biogenic amine receptor 0.0029 0.0204 0.0269
Onchocerca volvulus 0.0051 0.0486 0.0887
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0085 0.0188
Schistosoma mansoni hypothetical protein 0.0029 0.0204 0.0269
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.002 0.0093 0.0442
Loa Loa (eye worm) hypothetical protein 0.0037 0.0309 0.0407
Loa Loa (eye worm) hypothetical protein 0.0051 0.0488 0.0644
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0204 0.0204
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0055 0.0055
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0204 0.0204
Echinococcus granulosus orexin receptor type 2 0.0029 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0486 0.1368
Echinococcus multilocularis cysteine protease 0.0051 0.0486 0.0486
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0204 0.0204
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.002 0.0093 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0079 0.5831
Loa Loa (eye worm) hypothetical protein 0.0035 0.0285 0.0376
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0055 0.0055
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0029 0.0204 0.0204
Echinococcus granulosus sex peptide receptor 0.0029 0.0204 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Entamoeba histolytica cysteine protease, putative 0.0016 0.0049 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Loa Loa (eye worm) beta-lactamase 0.0035 0.0285 0.0376
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0024 0.0042
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Echinococcus granulosus nibrin 0.002 0.0093 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Schistosoma mansoni neuropeptide receptor 0.0029 0.0204 0.0269
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Schistosoma mansoni hypothetical protein 0.0062 0.0623 0.0823
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0441 0.411
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Schistosoma mansoni opsin-like receptor 0.0029 0.0204 0.0269
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0029 0.0204 0.0269
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0085 0.0148
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0079 0.006
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0624 0.7578 1
Echinococcus granulosus cathepsin L 0.003 0.0226 0.0226
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0123 0.0307
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0079 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0093 0.0204
Brugia malayi F/Y-rich N-terminus family protein 0.0014 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0098 0.1063 0.1403
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.2099 0.277
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3399 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Schistosoma mansoni hypothetical protein 0.0046 0.0424 0.0559
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0285 0.1003
Giardia lamblia Cathepsin B precursor 0.0096 0.1038 0.2953
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0016 0.0049 0.0448
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0024 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0085 0.0708
Schistosoma mansoni adenoreceptor 0.0029 0.0204 0.0269
Onchocerca volvulus 0.0048 0.0441 0.0805
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.1063 0.1063
Brugia malayi Cathepsin L-like precursor 0.0037 0.0309 0.0539
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0182 0.2106 0.2106
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0093 0.0204
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0486 0.1368
Brugia malayi Serotonin receptor 0.0029 0.0204 0.0356
Schistosoma mansoni topbp1 0.002 0.0093 0.0123
Plasmodium falciparum importin beta, putative 0.0058 0.0575 1
Schistosoma mansoni hypothetical protein 0.0065 0.0661 0.0873
Schistosoma mansoni amine GPCR 0.0029 0.0204 0.0269
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0204 0.0204
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0204 0.0204
Echinococcus multilocularis expressed conserved protein 0.0092 0.099 0.099
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Entamoeba histolytica hypothetical protein 0.0047 0.0438 0.1226
Plasmodium falciparum serine repeat antigen 4 0.0016 0.0049 0.0448
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus granulosus cathepsin L cysteine protease 0.003 0.0226 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0204 0.0269
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0123 0.0123
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0204 0.0269
Brugia malayi cathepsin L-like cysteine proteinase 0.0016 0.0049 0.0085
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0285 0.0772
Entamoeba histolytica hypothetical protein 0.002 0.0093 0.0204
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0489 0.0646
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0486 0.8386
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0575 0.5484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0309 0.0843
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.0497 0.0497
Echinococcus granulosus ferritin 0.0017 0.0059 0.0059
Entamoeba histolytica cysteine protease, putative 0.0016 0.0049 0.0073
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0204 0.0204
Onchocerca volvulus 0.002 0.0093 0.017
Toxoplasma gondii ABC1 family protein 0.0035 0.0285 0.2571
Schistosoma mansoni hypothetical protein 0.0031 0.0236 0.0311
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Brugia malayi cathepsin F-like cysteine proteinase 0.0016 0.0049 0.0085
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0486 0.8386
Toxoplasma gondii cathepsin CPC1 0.0016 0.0049 0.0243
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Plasmodium vivax vivapain-2 0.0051 0.0486 0.8386
Loa Loa (eye worm) hypothetical protein 0.0048 0.0441 0.0582
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0079 0.017
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0204 0.0356
Schistosoma mansoni hypothetical protein 0.0041 0.0352 0.0465
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0093 0.0214
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0631 0.1103
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0204 0.0204
Loa Loa (eye worm) RNA binding protein 0.0063 0.0631 0.0832
Loa Loa (eye worm) cysteine protease 0.0051 0.0486 0.0641
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Toxoplasma gondii preprocathepsin c precursor, putative 0.0016 0.0049 0.0243
Entamoeba histolytica cysteine proteinase 1, putative 0.003 0.0226 0.0598
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.1063 0.3079
Echinococcus granulosus survival motor neuron protein 1 0.0474 0.5721 0.5721
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0486 0.1433
Loa Loa (eye worm) hypothetical protein 0.0048 0.0441 0.0582
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0065 0.0661 0.0873
Onchocerca volvulus 0.0029 0.0204 0.0372
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.2622 1
Schistosoma mansoni biogenic amine receptor 0.0029 0.0204 0.0269
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0079 0.0079
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0123 0.0123
Brugia malayi PHD-finger family protein 0.0077 0.0804 0.1405
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0085 0.0599
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0085 0.0389
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0285 0.0772
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0049 0.0073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3399 1
Brugia malayi cathepsin L-like precursor 0.0037 0.0309 0.0539
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0285 0.1003
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0123 0.1794
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0631 0.0832
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0285 0.1671
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0049 0.0073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0226 0.0598
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0204 0.0269
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0285 0.1671
Onchocerca volvulus 0.0029 0.0204 0.0372
Mycobacterium tuberculosis Conserved protein 0.0035 0.0285 0.1003
Echinococcus multilocularis cpg binding protein 0.0036 0.0296 0.0296
Schistosoma mansoni ferritin 0.0017 0.0059 0.0078
Leishmania major DNA polymerase eta, putative 0.0019 0.0085 0.0599
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.1583 0.1583
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Brugia malayi hypothetical protein 0.0029 0.0204 0.0356
Schistosoma mansoni amine GPCR 0.0029 0.0204 0.0269
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0204 0.0269
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Echinococcus granulosus cathepsin b 0.0274 0.3247 0.3247
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0085 0.0188
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0204 0.0204
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0123 0.0162
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0016 0.0049 0.0064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0016 0.0049 0.0064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0204 0.0269
Plasmodium vivax unspecified product 0.003 0.0226 0.3666
Loa Loa (eye worm) hypothetical protein 0.0035 0.0285 0.0376
Plasmodium falciparum serine repeat antigen 2 0.0016 0.0049 0.0448
Entamoeba histolytica cysteine protease, putative 0.003 0.0226 0.0598
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0204 0.0269
Echinococcus granulosus importin subunit beta 1 0.0058 0.0575 0.0575
Schistosoma mansoni DNA polymerase eta 0.0019 0.0085 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.0292 0.0385
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0292 0.4859
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0055 0.0055
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0204 0.0356
Echinococcus granulosus expressed conserved protein 0.0092 0.099 0.099
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0016 0.0049 0.0073
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0059 0.0223
Schistosoma mansoni opsin-like receptor 0.0029 0.0204 0.0269
Schistosoma mansoni apoferritin-2 0.0017 0.0059 0.0078
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0016 0.0049 0.0448
Echinococcus multilocularis neuropeptide receptor A26 0.0029 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0064
Loa Loa (eye worm) hypothetical protein 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0019 0.0085 0.0112
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0204 0.0204
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0085 0.0188
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0055 0.0302
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0029 0.0204 0.0269
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0032
Treponema pallidum DNA ligase (lig) 0.002 0.0093 0.0103
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0441 0.1604
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.2099 0.2099
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0438 0.1284
Echinococcus granulosus GPCR family 2 0.0031 0.0236 0.0236
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0014 0.0028 0.0049
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0204 0.0204
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0204 0.0204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0093 0.0214
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0441 0.2671
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0371 0.0371
Schistosoma mansoni hypothetical protein 0.0031 0.0236 0.0311
Onchocerca volvulus 0.0051 0.0486 0.0887
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0093 0.0204
Echinococcus granulosus neuropeptide receptor 0.0029 0.0204 0.0204
Schistosoma mansoni ran 0.0022 0.0123 0.0162
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0285 0.0285
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0204 0.0204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0051 0.0486 0.4618
Plasmodium vivax serine-repeat antigen (SERA) 0.0016 0.0049 0.0448

Activities

Activity type Activity value Assay description Source Reference
Decrease (functional) = 55 % Decrease in paw volume by the effect of compound at a dose of 10 mg/kg ChEMBL. 3875725
ED50 (functional) > 130 mg kg-1 Effective dose determined by mouse phenyl-p-benzoquinone writhing (PQW) assay after peroral administration ChEMBL. 3875725
ED50 (functional) > 130 mg kg-1 Effective dose determined by mouse phenyl-p-benzoquinone writhing (PQW) assay after peroral administration ChEMBL. 3875725

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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