Detailed information for compound 253059

Basic information

Technical information
  • TDR Targets ID: 253059
  • Name: 6-chloroacridin-2-amine
  • MW: 228.677 | Formula: C13H9ClN2
  • H donors: 1 H acceptors: 1 LogP: 3.47 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1ccc2c(c1)cc1c(n2)cc(cc1)Cl
  • InChi: 1S/C13H9ClN2/c14-10-2-1-8-5-9-6-11(15)3-4-12(9)16-13(8)7-10/h1-7H,15H2
  • InChiKey: FMJZJKQGQIXNDY-UHFFFAOYSA-N  

Network

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Synonyms

  • 6-chloro-2-acridinamine
  • (6-chloroacridin-2-yl)amine
  • 40505-20-2
  • ACRIDINE, 2-AMINO-6-CHLORO-
  • BRN 0166510
  • 3-Amino-8-chloroacridine (European)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0196 0.0196
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0092 0.0158
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0043 0.0268 0.4645
Loa Loa (eye worm) troponin I 0.0085 0.0608 0.104
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0671 0.0671
Onchocerca volvulus Cathepsin F homolog 0.0081 0.0577 0.1493
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0226 0.1132
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0577 0.0987
Brugia malayi hypothetical protein 0.0045 0.0284 0.0486
Onchocerca volvulus 0.0081 0.0577 0.1493
Trypanosoma brucei ISWI complex protein 0.0016 0.0048 0.0243
Brugia malayi Bromodomain containing protein 0.0077 0.0548 0.0938
Echinococcus multilocularis dnaJ subfamily B 0.0325 0.2546 0.2546
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0577 0.0987
Leishmania major GTP-binding protein, putative 0.0017 0.0059 0.0297
Loa Loa (eye worm) hypothetical protein 0.0733 0.5843 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Schistosoma mansoni hypothetical protein 0.0034 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Onchocerca volvulus 0.0023 0.0107 0.0242
Echinococcus granulosus chromobox protein 1 0.0071 0.0494 0.0494
Schistosoma mansoni cathepsin S (C01 family) 0.0043 0.0268 0.0268
Giardia lamblia Cysteine protease 0.0043 0.0268 0.1345
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0083
Brugia malayi cathepsin F-like cysteine proteinase 0.0038 0.0232 0.0397
Giardia lamblia Cathepsin L precursor 0.0043 0.0268 0.1345
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0097 0.0706 0.1208
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0058 0.0387 0.0663
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0196 0.0985
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0097 0.0706 0.0706
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0043 0.0268 0.4645
Schistosoma mansoni bromodomain containing protein 0.0065 0.0452 0.0452
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0196 0.0985
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0011 0.0057
Plasmodium falciparum serine repeat antigen 8 0.0043 0.0268 0.4645
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0267 0.1341
Schistosoma mansoni hypothetical protein 0.0244 0.1897 0.1897
Schistosoma mansoni rotamase 0.0027 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Loa Loa (eye worm) hypothetical protein 0.0043 0.0269 0.0461
Entamoeba histolytica serine/threonine protein kinase, putative 0.0075 0.0532 0.7299
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0075 0.0532 0.0911
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0043 0.0268 0.3673
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0068 0.1181
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0342 0.0586
Schistosoma mansoni hypothetical protein 0.0073 0.0512 0.0512
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0577 0.7908
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.0785 0.1344
Schistosoma mansoni hypothetical protein 0.003 0.0162 0.0162
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0342 0.1719
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0016 0.0285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Loa Loa (eye worm) LGC-31 protein 0.0097 0.0706 0.1208
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0043 0.0043
Onchocerca volvulus 0.0043 0.0268 0.067
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0101 0.0101
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0226 0.5
Entamoeba histolytica cysteine protease, putative 0.0043 0.0268 0.3673
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.001 0 0.0001
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0026 0.0132 0.0663
Entamoeba histolytica hypothetical protein 0.0052 0.0345 0.4726
Leishmania major cathepsin L-like protease 0.0081 0.0577 0.2895
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.015 0.0751
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0196 0.0336
Entamoeba histolytica cysteine proteinase 2 0.0081 0.0577 0.7908
Trypanosoma cruzi PAB1-binding protein , putative 0.0038 0.0231 0.0395
Echinococcus multilocularis GPCR, family 2 0.0034 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.003 0.0162 0.0277
Echinococcus granulosus cathepsin L 0.0081 0.0577 0.0577
Entamoeba histolytica hypothetical protein 0.0073 0.0511 0.701
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0015 0.0042 0.1124
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0043 0.0268 0.1345
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0052 0.0345 0.059
Echinococcus multilocularis chromobox protein 1 0.0071 0.0494 0.0494
Giardia lamblia Cathepsin L precursor 0.0043 0.0268 0.1345
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0043 0.0268 0.1345
Onchocerca volvulus 0.0045 0.0284 0.0713
Echinococcus multilocularis cysteine protease 0.0081 0.0577 0.0577
Echinococcus multilocularis cathepsin L 0.0043 0.0268 0.0268
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0284 0.0486
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0016 0.0016
Loa Loa (eye worm) MH2 domain-containing protein 0.0095 0.0688 0.1178
Trypanosoma cruzi ISWI complex protein 0.0016 0.0048 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Toxoplasma gondii peptidylprolyl isomerase 0.0026 0.0132 0.0663
Loa Loa (eye worm) hypothetical protein 0.004 0.0243 0.0416
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0269 0.1351
Onchocerca volvulus 0.0081 0.0577 0.1493
Loa Loa (eye worm) hypothetical protein 0.0038 0.0231 0.0395
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0028
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0226 0.1132
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0196 0.0336
Plasmodium vivax JmjC domain containing protein 0.001 0 0.0002
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0043 0.0268 0.0268
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0226 0.1132
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0028
Trypanosoma cruzi polo-like protein kinase, putative 0.0075 0.0532 0.0911
Giardia lamblia Cathepsin L precursor 0.0043 0.0268 0.1345
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0081 0.0577 0.2895
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0043 0.0268 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0043 0.0268 0.1345
Entamoeba histolytica hypothetical protein 0.0073 0.0511 0.701
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0162 0.0277
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0256 0.1992 0.3409
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.1076 0.1076
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0097 0.0706 0.0706
Giardia lamblia Cysteine protease 0.0043 0.0268 0.1345
Brugia malayi cytoplasmic intermediate filament protein 0.0011 0.0016 0.0027
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0016 0.0028
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0255 0.0255
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0117 0.0201
Brugia malayi Troponin T 0.005 0.0329 0.0563
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.001 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Plasmodium falciparum serine repeat antigen 2 0.0043 0.0268 0.4645
Schistosoma mansoni eyes absent homolog 0.0032 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0073 0.0512 0.0877
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0226 0.0386
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Loa Loa (eye worm) hypothetical protein 0.0048 0.0311 0.0533
Entamoeba histolytica hypothetical protein 0.0019 0.0073 0.1
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0108 0.0542
Schistosoma mansoni hypothetical protein 0.0325 0.2546 0.2545
Schistosoma mansoni ran 0.0017 0.0059 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Schistosoma mansoni troponin I 0.0085 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0032 0.0183 0.0314
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0097 0.0706 0.0706
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0033 0.0164
Trypanosoma cruzi cysteine proteinase, putative 0.0081 0.0577 0.0987
Brugia malayi Troponin T 0.005 0.0329 0.0563
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0017 0.0061 0.0061
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0097 0.0706 0.0706
Echinococcus multilocularis importin subunit beta 1 0.0023 0.0108 0.0108
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0045 0.0284 0.0284
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0226 0.1132
Brugia malayi Cathepsin L-like precursor 0.0038 0.0232 0.0397
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0512 0.0877
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0017 0.0059 0.0101
Entamoeba histolytica cysteine protease, putative 0.0043 0.0268 0.3673
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis dna polymerase eta 0.0012 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0031 0.0174 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Schistosoma mansoni cpg binding protein 0.0026 0.0133 0.0133
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0733 0.5843 0.5843
Toxoplasma gondii cathepsin CPL 0.0081 0.0577 0.2895
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0268 0.1345
Mycobacterium ulcerans hypothetical protein 0.0024 0.0117 0.3118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0097 0.0706 0.1208
Echinococcus multilocularis protein patched 0.0043 0.0269 0.0269
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0097 0.0706 0.0706
Brugia malayi Cation transporter family protein 0.0097 0.0706 0.1208
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0423 0.0423
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0267 0.1341
Schistosoma mansoni troponin I 0.0085 0.0608 0.0608
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0212 0.0212
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0075 0.0532 0.0532
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0081 0.0577 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0671 0.0671
Schistosoma mansoni hypothetical protein 0.0034 0.0196 0.0196
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0017 0.0059 0.0297
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0043 0.0268 0.1345
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0043 0.0268 0.4645
Echinococcus granulosus peregrin 0.0032 0.0181 0.0181
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0017 0.0059 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0532 0.0532
Echinococcus multilocularis cathepsin L cysteine protease 0.0081 0.0577 0.0577
Brugia malayi MAP kinase sur-1 0.0052 0.0342 0.0586
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0226 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0081 0.0577 0.0577
Schistosoma mansoni hypothetical protein 0.0016 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0021 0.0092 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0227 0.1138
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0464 0.0464
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0045 0.0284 0.0486
Loa Loa (eye worm) hypothetical protein 0.0107 0.0785 0.1344
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0464 0.2328
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0081 0.0577 0.0577
Brugia malayi hypothetical protein 0.0025 0.0122 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0268 0.1345
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0016 0.0083
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0225
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0733 0.5843 0.5843
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0342 0.1719
Onchocerca volvulus 0.0043 0.0268 0.067
Onchocerca volvulus 0.0081 0.0577 0.1493
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0268 0.1345
Echinococcus multilocularis nAChR subunit 0.0097 0.0706 0.0706
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0196 0.0335
Brugia malayi serine/threonine-protein kinase plk-2 0.0075 0.0532 0.0911
Loa Loa (eye worm) hypothetical protein 0.0045 0.0283 0.0484
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0268 0.0268
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0577 0.0987
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0026 0.0026
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0016 0.0016
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0043 0.0268 0.0459
Onchocerca volvulus 0.0241 0.1867 0.4932
Plasmodium falciparum cysteine proteinase falcipain 1 0.0081 0.0577 1
Trichomonas vaginalis rotamase, putative 0.0026 0.0132 0.0663
Echinococcus granulosus nAChR subunit 0.0097 0.0706 0.0706
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0196 0.0336
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0043 0.0268 0.0459
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0117
Brugia malayi Cathepsin L-like precursor 0.0081 0.0577 0.0987
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0238 0.0238
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0577 0.7908
Giardia lamblia Cathepsin B precursor 0.0043 0.0268 0.1345
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0464 0.0794
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0006
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0236 0.0236
Schistosoma mansoni chromobox protein 0.0012 0.0016 0.0016
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0016 0.0028
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.001 0 0.0001
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.005 0.0329 0.0833
Brugia malayi Cathepsin L-like precursor 0.0043 0.0268 0.0459
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0017 0.0059 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0268 0.1345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0268 0.1345
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0083
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0268 0.0459
Echinococcus multilocularis microtubule associated protein 2 0.1248 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Plasmodium vivax unspecified product 0.0081 0.0577 1
Plasmodium vivax unspecified product 0.0043 0.0268 0.4645
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0671 0.0671
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0238 0.0408
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0243 0.1219
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Loa Loa (eye worm) hypothetical protein 0.0021 0.0093 0.0159
Echinococcus multilocularis glycine receptor subunit beta 0.0097 0.0706 0.0706
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.0532 0.2673
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0011
Echinococcus granulosus dna polymerase kappa 0.0022 0.0101 0.0101
Giardia lamblia Cathepsin B precursor 0.0043 0.0268 0.1345
Echinococcus granulosus geminin 0.039 0.3073 0.3073
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0038 0.0232 0.0397
Brugia malayi ImpB/MucB/SamB family protein 0.0012 0.0023 0.0039
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0117 0.3118
Schistosoma mansoni kinase 0.0039 0.0235 0.0235
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Trichomonas vaginalis ran, putative 0.0017 0.0059 0.0297
Plasmodium vivax importin-beta 2, putative 0.0023 0.0108 0.1871
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0006
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0045 0.0284 0.0486
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.0532 0.2673
Loa Loa (eye worm) hypothetical protein 0.0024 0.0117 0.0201
Schistosoma mansoni hypothetical protein 0.0041 0.0257 0.0257
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0194 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0081 0.0577 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0012 0.0023 0.0023
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0511 0.0511
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0117 0.1607
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0196 0.0196
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0012 0.0016 0.0285
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.006 0.2155
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Onchocerca volvulus 0.0052 0.0345 0.0875
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0269 0.0269
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0196 0.0196
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0494 0.0845
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0097 0.0706 0.0706
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Loa Loa (eye worm) hypothetical protein 0.0072 0.0502 0.086
Loa Loa (eye worm) hypothetical protein 0.005 0.0329 0.0563
Echinococcus granulosus Chromobox protein 3 0.0012 0.0016 0.0016
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0256 0.1992 1
Loa Loa (eye worm) helicase 0.0012 0.0016 0.0028
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0225
Giardia lamblia Cathepsin B precursor 0.0043 0.0268 0.1345
Schistosoma mansoni troponin t invertebrate 0.0105 0.0772 0.0772
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0058 0.0292
Echinococcus multilocularis glycine receptor subunit beta 0.0097 0.0706 0.0706
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Brugia malayi Ets-domain containing protein 0.0058 0.0387 0.0663
Brugia malayi CHE-14 protein 0.0043 0.0269 0.0461
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0577 0.1493
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0196 0.0196
Schistosoma mansoni hypothetical protein 0.0041 0.0257 0.0257
Brugia malayi cathepsin B-like cysteine proteinase 0.0733 0.5843 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0196 0.0196
Echinococcus granulosus chromobox protein 1 0.0071 0.0494 0.0494
Loa Loa (eye worm) hypothetical protein 0.0032 0.0183 0.0314
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Echinococcus multilocularis chromobox protein 2 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0081 0.0577 0.0987
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0108 0.0542
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0268 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0045 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0039 0.0237 0.0406
Loa Loa (eye worm) fibroinase 0.0081 0.0577 0.0987
Echinococcus multilocularis expressed protein 0.0027 0.0137 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0016 0.0083
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0041 0.0255 0.3492
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0019 0.0073 0.0366
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0268 0.0459
Echinococcus multilocularis Chromo domain 0.0012 0.0016 0.0016
Trypanosoma brucei unspecified product 0.002 0.0082 0.0411
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0256 0.1992 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0028
Loa Loa (eye worm) hypothetical protein 0.0053 0.0347 0.0594
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0058 0.0292
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0021 0.0096 0.0164
Loa Loa (eye worm) hypothetical protein 0.0041 0.0255 0.0436
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0019 0.0073 0.0366
Leishmania major cathepsin L-like protease 0.0081 0.0577 0.2895
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0117
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0342 0.0586
Echinococcus multilocularis lamin 0.0021 0.0096 0.0096
Brugia malayi Inositol-1 0.0037 0.0226 0.0386
Leishmania major cathepsin L-like protease 0.0081 0.0577 0.2895
Brugia malayi intermediate filament protein 0.0021 0.0096 0.0164
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0097 0.0706 0.1208
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0117 0.3118
Brugia malayi Protein cec-1. 0.0012 0.0016 0.0028
Brugia malayi RNA, U transporter 1 0.0065 0.0449 0.0768
Schistosoma mansoni hypothetical protein 0.0073 0.0511 0.0511
Plasmodium falciparum serine repeat antigen 4 0.0043 0.0268 0.4645
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0083
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0464 0.2328
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0083
Loa Loa (eye worm) hypothetical protein 0.0038 0.0232 0.0397
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0016 0.0016
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0097 0.0706 0.1208
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0577 0.0987
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0017 0.0059 0.1025
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0101 0.2114
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0729 0.0729
Brugia malayi M-phase phosphoprotein, mpp8 0.0012 0.0016 0.0028
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0038 0.0232 0.0397
Leishmania major cathepsin L-like protease 0.0081 0.0577 0.2895
Trypanosoma cruzi PAB1-binding protein , putative 0.0038 0.0231 0.0395
Schistosoma mansoni lamin 0.0021 0.0096 0.0096
Brugia malayi chromobox protein homolog 3 0.004 0.0243 0.0416
Trichomonas vaginalis set domain proteins, putative 0.0241 0.1867 0.9373
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Loa Loa (eye worm) hypothetical protein 0.0085 0.0608 0.104
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Echinococcus multilocularis geminin 0.039 0.3073 0.3073
Toxoplasma gondii histone lysine methyltransferase SET1 0.0047 0.03 0.1507
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0227 0.1138
Schistosoma mansoni importin beta-1 0.0023 0.0108 0.0108
Schistosoma mansoni inositol monophosphatase 0.0037 0.0226 0.0225
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0733 0.5843 0.5843
Entamoeba histolytica cysteine protease, putative 0.0043 0.0268 0.3673
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0268 0.0268
Schistosoma mansoni nAChR subunit 0.0097 0.0706 0.0706
Plasmodium falciparum ataxin-2 like protein, putative 0.0038 0.0231 0.4
Echinococcus granulosus importin subunit beta 1 0.0023 0.0108 0.0108
Onchocerca volvulus 0.0081 0.0577 0.1493
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0265 0.0265
Onchocerca volvulus 0.0081 0.0577 0.1493
Echinococcus multilocularis troponin i 0.0085 0.0608 0.0608
Brugia malayi excitatory GABA receptor EXP-1A 0.0097 0.0706 0.1208
Onchocerca volvulus 0.0052 0.0345 0.0875
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0671 0.0671
Echinococcus multilocularis cathepsin L cysteine protease 0.0081 0.0577 0.0577
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0172 0.0861
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0017 0.0059 0.1025
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0068 0.1181
Schistosoma mansoni nAChR subunit 0.0097 0.0706 0.0706
Brugia malayi PHD-finger family protein 0.0027 0.0138 0.0235
Echinococcus multilocularis cathepsin b 0.0733 0.5843 0.5843
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0097 0.0706 0.0706
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0081 0.0577 0.0987
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.0785 0.1344
Schistosoma mansoni cpg binding protein 0.0026 0.0133 0.0133
Schistosoma mansoni inositol monophosphatase 0.0037 0.0226 0.0225
Brugia malayi hypothetical protein 0.0045 0.0284 0.0486
Echinococcus granulosus cytoplasmic intermediate filament protein 0.001 0.0006 0.0006
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0342 0.1719
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0196 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0101 0.0174
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0097 0.0706 0.1208
Brugia malayi CXXC zinc finger family protein 0.0023 0.0107 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0083
Brugia malayi Cathepsin L-like precursor 0.0081 0.0577 0.0987
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0172 0.0172
Leishmania major hypothetical protein, conserved 0.0038 0.0231 0.1158
Onchocerca volvulus 0.0476 0.3769 1
Brugia malayi Pre-SET motif family protein 0.0031 0.0172 0.0294
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0423 0.0423
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0011 0.0057
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0159 0.0159
Brugia malayi cathepsin F-like cysteine proteinase 0.0043 0.0268 0.0459
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0577 0.7908
Loa Loa (eye worm) hypothetical protein 0.0051 0.0332 0.0569
Onchocerca volvulus 0.0045 0.0284 0.0713
Echinococcus granulosus glycine receptor subunit alpha 1 0.0097 0.0706 0.0706
Loa Loa (eye worm) hypothetical protein 0.01 0.0729 0.1248
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0097 0.0706 0.0706
Brugia malayi cathepsin L-like cysteine proteinase 0.0043 0.0268 0.0459
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0196 0.0196
Toxoplasma gondii cathepsin CPC1 0.0043 0.0268 0.1345
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0196 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0268 0.1345
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Echinococcus granulosus cathepsin b 0.0733 0.5843 0.5843
Plasmodium falciparum serine repeat antigen 7 0.0043 0.0268 0.4645
Plasmodium vivax serine-repeat antigen (SERA) 0.0043 0.0268 0.4645
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0464 0.0464
Echinococcus granulosus cathepsin l1 0.0081 0.0577 0.0577
Echinococcus multilocularis cathepsin L 0.0081 0.0577 0.0577
Echinococcus granulosus glycine receptor subunit alpha 1 0.0097 0.0706 0.0706
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Brugia malayi Cation transporter family protein 0.0097 0.0706 0.1208
Brugia malayi isocitrate dehydrogenase 0.0034 0.0196 0.0336
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0043 0.0268 0.0268
Schistosoma mansoni hypothetical protein 0.0034 0.0196 0.0196
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0097 0.0706 0.0706
Schistosoma mansoni hypothetical protein 0.039 0.3073 0.3073
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0058 0.0292
Brugia malayi Cathepsin L-like precursor 0.0081 0.0577 0.0987
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0162 0.0812
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0075 0.0532 0.2673
Giardia lamblia Hypothetical protein 0.0043 0.0268 0.1345
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0742 0.0742
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0117
Schistosoma mansoni acetylcholine receptor subunit beta 0.0045 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0041 0.0257 0.0439
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0577 0.0987
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0097 0.0706 0.0706
Brugia malayi CHD4 protein 0.0015 0.0043 0.0073
Echinococcus granulosus cysteine protease 0.0081 0.0577 0.0577
Brugia malayi Heterochromatin protein 1 0.0071 0.0494 0.0845
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0097 0.0706 0.1208
Loa Loa (eye worm) GABA receptor subunit 0.0052 0.0345 0.059
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Giardia lamblia Hypothetical protein 0.0043 0.0268 0.1345
Brugia malayi hypothetical protein 0.0012 0.0016 0.0028
Brugia malayi Pre-SET motif family protein 0.0212 0.1632 0.2793
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0043 0.0268 0.0268
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0196 0.0196
Brugia malayi jmjC domain containing protein 0.0097 0.0705 0.1207
Schistosoma mansoni cathepsin s 0.0038 0.0232 0.0232
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0016 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.006 0.2155
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0226 0.0386
Schistosoma mansoni chromobox protein 0.0071 0.0494 0.0494
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0117 0.0588
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0671 0.0671
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0226 0.1132
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0284 0.0486
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0083
Giardia lamblia Cathepsin L-like protease 0.0043 0.0268 0.1345
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0028
Loa Loa (eye worm) ACC-1 protein 0.0097 0.0706 0.1208
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.1632 0.2793
Echinococcus multilocularis musashi 0.0021 0.0096 0.0096
Plasmodium falciparum serine repeat antigen 1 0.0043 0.0268 0.4645
Brugia malayi Cathepsin L-like precursor 0.0043 0.0268 0.0459
Plasmodium falciparum serine repeat antigen 9 0.0043 0.0268 0.4645
Giardia lamblia Cathepsin B precursor 0.0043 0.0268 0.1345
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0105 0.0772 0.2014
Plasmodium vivax unspecified product 0.0038 0.0232 0.4021
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0082 0.014
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0117 0.0588
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0097 0.0706 0.1208
Schistosoma mansoni nAChR subunit 0.0045 0.0284 0.0284
Giardia lamblia Cathepsin L precursor 0.0043 0.0268 0.1345
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0268 0.1345
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0045 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Loa Loa (eye worm) hypothetical protein 0.0034 0.0196 0.0335
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0016 0.0083
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0043 0.0268 0.1345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0162 0.0162
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0671 0.1148
Echinococcus granulosus cpg binding protein 0.0026 0.0133 0.0133
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0117 0.1607
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.0311 0.0311
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0068 0.0116
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0097 0.0706 0.0706
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Schistosoma mansoni acetylcholine receptor-related 0.0045 0.0284 0.0284
Schistosoma mansoni hypothetical protein 0.0017 0.0061 0.0061
Echinococcus multilocularis nAChR subunit 0.0052 0.0345 0.0345
Schistosoma mansoni patched 1 0.0043 0.0269 0.0269
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0043 0.0268 0.4645
Echinococcus multilocularis GA binding protein alpha chain 0.0058 0.0387 0.0387
Trichomonas vaginalis importin beta-1, putative 0.0019 0.0073 0.0366
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0342 0.0342
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0464 0.6357
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0043 0.0042
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0342 0.0342
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Onchocerca volvulus 0.0097 0.0706 0.1837
Echinococcus granulosus expressed conserved protein 0.0094 0.0681 0.0681
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0101 0.0174
Plasmodium vivax serine-repeat antigen (SERA) 0.0043 0.0268 0.4645
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0016 0.0028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0196 0.0196
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0097 0.0706 0.0706
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Brugia malayi hypothetical protein 0.0045 0.0284 0.0486
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0217 0.0217
Trypanosoma brucei importin beta-1 subunit, putative 0.0023 0.0108 0.0542
Schistosoma mansoni neurotransmitter gated ion channel 0.0045 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0024 0.0117 0.0201
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0027 0.0137 0.0235
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0511 0.0511
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0049 0.0323 0.0322
Schistosoma mansoni nAChR subunit 0.0097 0.0706 0.0706
Echinococcus granulosus cathepsin L cysteine proteinase 0.0081 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Giardia lamblia Cathepsin L precursor 0.0043 0.0268 0.1345
Brugia malayi Fli-1 protein 0.0175 0.1333 0.2281
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.006 0.2155
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0342 0.1719
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.0532 0.2673
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0494 0.2478
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0101 0.0174
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0117 0.1607
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0226 0.3092
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0063 0.0063
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0043 0.0268 0.4645
Brugia malayi cathepsin L-like precursor 0.0043 0.0268 0.0459
Loa Loa (eye worm) troponin T 0.005 0.0329 0.0563
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0083
Leishmania major importin beta-1 subunit, putative 0.0019 0.0073 0.0366
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0026 0.0132 0.1812
Onchocerca volvulus 0.0097 0.0706 0.1837
Echinococcus granulosus lamin dm0 0.0021 0.0096 0.0096
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0043 0.0268 0.4645
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0268 0.1345
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0058 0.0292
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0255 0.0255
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0101 0.0509
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0033 0.0164
Loa Loa (eye worm) intermediate filament protein 0.0021 0.0096 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0137 0.0689
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0196 0.3402
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0238 0.0238
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0045 0.0284 0.0486
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0464 0.0794
Brugia malayi PHD-finger family protein 0.0013 0.0027 0.0047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0028
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Echinococcus multilocularis cysteine protease 0.0081 0.0577 0.0577
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.0532 0.2673
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0043 0.0268 0.1345
Giardia lamblia Cathepsin L precursor 0.0043 0.0268 0.1345
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0081 0.0577 0.0577
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0045 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Schistosoma mansoni intermediate filament proteins 0.0021 0.0096 0.0096
Plasmodium vivax ataxin-2 like protein, putative 0.0038 0.0231 0.4
Brugia malayi PHD-finger family protein 0.003 0.0162 0.0277
Loa Loa (eye worm) acetylcholine receptor protein 0.0045 0.0284 0.0486
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Schistosoma mansoni lamin 0.0021 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0049 0.032 0.0548
Brugia malayi hypothetical protein 0.0073 0.0511 0.0875
Echinococcus multilocularis peregrin 0.0032 0.0181 0.0181
Entamoeba histolytica cysteine proteinase, putative 0.0043 0.0268 0.3673
Echinococcus granulosus glycine receptor subunit beta 0.0097 0.0706 0.0706
Echinococcus multilocularis chromobox protein 1 0.0071 0.0494 0.0494
Echinococcus granulosus cathepsin L 0.0043 0.0268 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0268 0.1345
Schistosoma mansoni terminal deoxycytidyl transferase 0.0012 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Giardia lamblia Cysteine protease 0.0043 0.0268 0.1345
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0269 0.0269
Schistosoma mansoni hypothetical protein 0.039 0.3073 0.3073
Schistosoma mansoni cathepsin C 0.0043 0.0268 0.0268
Brugia malayi Troponin I 0.0085 0.0608 0.104
Plasmodium vivax vivapain-1 0.0081 0.0577 1
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0101 0.0509
Entamoeba histolytica hypothetical protein 0.0073 0.0511 0.701
Trypanosoma cruzi cysteine peptidase, putative 0.0038 0.0232 0.0397
Echinococcus granulosus intermediate filament protein 0.0021 0.0096 0.0096
Plasmodium falciparum phd finger protein, putative 0.003 0.0162 0.2806
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0017 0.0059 0.0297
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0043 0.0268 0.4645
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0001 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0043 0.0268 0.1345
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0577 0.0987
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0097 0.0706 0.0706
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0012 0.0214
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0117 0.0201
Echinococcus multilocularis lamin dm0 0.0021 0.0096 0.0096
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0311 0.0311
Entamoeba histolytica hypothetical protein 0.0012 0.0016 0.0225
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Brugia malayi jmjC domain containing protein 0.0039 0.0238 0.0408
Plasmodium vivax heterochromatin protein 1, putative 0.0012 0.0016 0.0285
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0081 0.0577 0.0987
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0097 0.0706 0.0706
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0342 0.1719
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0012 0.0023 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0117 0.0201
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0117 0.3118
Brugia malayi Importin beta-1 subunit 0.0023 0.0108 0.0185
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0733 0.5843 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0196 0.3402
Schistosoma mansoni cpg binding protein 0.0023 0.0107 0.0107
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0117 0.5443
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0162 0.0812
Onchocerca volvulus 0.0097 0.0706 0.1837
Loa Loa (eye worm) ACC-1 protein 0.0097 0.0706 0.1208
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0243 0.0603
Schistosoma mansoni nAChR subunit 0.0097 0.0706 0.0706
Trypanosoma cruzi polo-like protein kinase, putative 0.0075 0.0532 0.0911
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0043 0.0268 0.4645
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0045 0.0284 0.0284
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.1076 0.1076
Plasmodium vivax hypothetical protein, conserved 0.003 0.0162 0.2806
Onchocerca volvulus Troponin I homolog 0.0085 0.0608 0.1576
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0162 0.0162
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0043 0.0268 0.4645
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0196 0.0336
Giardia lamblia Encystation-specific protease 0.0043 0.0268 0.1345
Trypanosoma cruzi DNA polymerase eta, putative 0.0012 0.0023 0.0039
Echinococcus multilocularis expressed conserved protein 0.0094 0.0681 0.0681
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Trypanosoma brucei PAB1-binding protein , putative 0.0038 0.0231 0.1158
Onchocerca volvulus 0.0045 0.0284 0.0713
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0063 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0671 0.0671
Schistosoma mansoni cathepsin F (C01 family) 0.0043 0.0268 0.0268
Schistosoma mansoni ran 0.0017 0.0059 0.0059
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0284 0.0486
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Onchocerca volvulus 0.0021 0.0096 0.0212
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0028
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0464 0.0794
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0268 0.0459
Plasmodium vivax vivapain-2 0.0081 0.0577 1
Echinococcus granulosus chromobox protein 2 0.0012 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Schistosoma mansoni hypothetical protein 0.0085 0.0608 0.0608
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0464 0.0794
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0268 0.0268
Onchocerca volvulus Putative nachr subunit 0.0097 0.0706 0.1837
Leishmania major hypothetical protein, conserved 0.0016 0.0048 0.0243
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0097 0.0706 0.1208
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0081 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0024 0.0117 0.0201
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Echinococcus multilocularis zinc finger protein 0.0021 0.0094 0.0094
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0244 0.1897 0.3246
Echinococcus granulosus GPCR family 2 0.0034 0.0196 0.0196
Brugia malayi Cathepsin L-like cysteine proteinase 0.0043 0.0268 0.0459
Loa Loa (eye worm) hypothetical protein 0.0021 0.0096 0.0164
Giardia lamblia Kinase, PLK 0.0075 0.0532 0.2673
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0243 0.1219
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0075 0.0532 0.0532
Schistosoma mansoni cathepsin F (C01 family) 0.0081 0.0577 0.0577
Brugia malayi Cathepsin L-like precursor 0.0081 0.0577 0.0987
Schistosoma mansoni hypothetical protein 0.0041 0.0257 0.0257
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0733 0.5843 0.5843
Schistosoma mansoni neurotransmitter gated ion channel 0.0052 0.0345 0.0345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0268 0.1345
Brugia malayi MH2 domain containing protein 0.0095 0.0688 0.1178
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0039 0.0195
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0217 0.0217
Plasmodium falciparum serine repeat antigen 6 0.0043 0.0268 0.4645
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0097 0.0706 0.1208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0268 0.1345
Schistosoma mansoni chromobox protein 0.0071 0.0494 0.0494
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0097 0.0706 0.1208
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0268 0.0459
Giardia lamblia Cathepsin B precursor 0.0256 0.1992 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.0043 0.0268 0.1345
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0342 0.1719
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Entamoeba histolytica hypothetical protein 0.0043 0.0268 0.3673
Loa Loa (eye worm) troponin 0.005 0.0329 0.0563
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0117
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0026 0.0132 0.0226
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0342 0.0586
Entamoeba histolytica cysteine protease, putative 0.0043 0.0268 0.3673
Plasmodium vivax SET domain protein, putative 0.0031 0.0172 0.2975
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0268 0.0268
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0511 0.0511
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0043 0.0043
Entamoeba histolytica hypothetical protein 0.0073 0.0511 0.701
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0097 0.0706 0.1208
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0577 0.7908
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0226 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0083
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0097 0.0706 0.1208
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0097 0.0706 0.1208
Loa Loa (eye worm) fli-1 protein 0.0175 0.1333 0.2281
Brugia malayi hypothetical protein 0.0038 0.0231 0.0395
Echinococcus granulosus glycine receptor subunit alpha 1 0.0097 0.0706 0.0706
Schistosoma mansoni nAChR subunit 0.0097 0.0706 0.0706
Loa Loa (eye worm) transcription factor SMAD2 0.0095 0.0688 0.1178
Brugia malayi polk-prov protein 0.0014 0.0033 0.0056
Brugia malayi Cathepsin L-like precursor 0.0081 0.0577 0.0987
Entamoeba histolytica cysteine proteinase 1, putative 0.0081 0.0577 0.7908
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0012 0.0016 0.0285
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0226 0.1132
Trypanosoma cruzi cruzipain precursor, putative 0.0081 0.0577 0.0987
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0342 0.1719
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0038 0.0232 0.0397
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0097 0.0706 0.1208
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Brugia malayi hypothetical protein 0.0476 0.3769 0.6451
Loa Loa (eye worm) cathepsin B 0.0256 0.1992 0.3409
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0705 0.0705
Brugia malayi ImpB/MucB/SamB family protein 0.0012 0.0023 0.0039
Plasmodium falciparum importin beta, putative 0.0023 0.0108 0.1871
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0063 0.0063
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0068 0.2612
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0577 0.0987
Schistosoma mansoni microtubule-associated protein tau 0.1248 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.0532 0.2673
Giardia lamblia Cysteine protease 0.0043 0.0268 0.1345
Onchocerca volvulus 0.0042 0.0265 0.0662
Onchocerca volvulus 0.0021 0.0096 0.0212
Plasmodium falciparum ataxin-2 like protein, putative 0.0038 0.0231 0.4
Schistosoma mansoni zinc finger protein 0.0021 0.0094 0.0094
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0052 0.0345 0.059
Echinococcus granulosus cathepsin L cysteine protease 0.0081 0.0577 0.0577
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0705 0.0705
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0196 0.0335
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0097 0.0706 0.0706
Schistosoma mansoni hypothetical protein 0.0041 0.0257 0.0257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0268 0.1345
Loa Loa (eye worm) hypothetical protein 0.0038 0.0232 0.0397
Trypanosoma cruzi major cysteine proteinase, putative 0.0043 0.0268 0.0459
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0256 0.1992 0.1992
Echinococcus multilocularis cpg binding protein 0.0026 0.0133 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0058 0.0292
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0058 0.0292
Brugia malayi Cathepsin L-like precursor 0.0081 0.0577 0.0987
Giardia lamblia DINP protein human, muc B family 0.0015 0.0042 0.0213
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0036 0.018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0196 0.0196
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0097 0.0706 0.1208
Trichomonas vaginalis rotamase, putative 0.0027 0.0137 0.0689
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0083
Echinococcus multilocularis cathepsin b 0.0733 0.5843 0.5843
Brugia malayi hypothetical protein 0.0032 0.0183 0.0314
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0097 0.0706 0.1208
Plasmodium falciparum heterochromatin protein 1 0.0012 0.0016 0.0285
Echinococcus granulosus GA binding protein alpha chain 0.0058 0.0387 0.0387
Brugia malayi AF-10 protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0039
Schistosoma mansoni troponin I 0.0085 0.0608 0.0608
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0052 0.0345 0.059
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0342 0.0586
Loa Loa (eye worm) cysteine protease 0.0081 0.0577 0.0987
Trypanosoma cruzi cruzipain precursor, putative 0.0038 0.0232 0.0397
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0342 0.0342
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0464 0.0464
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0226 0.0226
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0097 0.0706 0.0706
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.0509
Schistosoma mansoni hypothetical protein 0.0034 0.0196 0.0196
Schistosoma mansoni cathepsin B (C01 family) 0.0043 0.0268 0.0268
Echinococcus granulosus nAChR subunit 0.0052 0.0345 0.0345
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0017 0.0059 0.0101
Leishmania major cathepsin L-like protease 0.0081 0.0577 0.2895
Echinococcus granulosus GTP binding nuclear protein Ran 0.0017 0.0059 0.0059
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0026 0.0132 0.0663
Giardia lamblia Cathepsin L-like protease 0.0043 0.0268 0.1345
Brugia malayi Ets-domain containing protein 0.0058 0.0387 0.0663
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0238 0.0238
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0196 0.0985
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0039 0.0195
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Brugia malayi cathepsin Z-like cysteine proteinase 0.0043 0.0268 0.0459
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0052 0.0345 0.059
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0097 0.0706 0.0706
Brugia malayi cathepsin L precursor 0.0043 0.0268 0.0459
Schistosoma mansoni zinc finger protein 0.0016 0.0048 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.0532 0.2673
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Brugia malayi Cation transporter family protein 0.0097 0.0706 0.1208
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0342 0.1719
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0416 0.0712
Echinococcus granulosus glycine receptor subunit beta 0.0097 0.0706 0.0706
Trypanosoma brucei polo-like protein kinase 0.0075 0.0532 0.2673
Schistosoma mansoni ets-related 0.0175 0.1333 0.1333
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Plasmodium falciparum serine repeat antigen 5 0.0043 0.0268 0.4645
Onchocerca volvulus 0.0024 0.0117 0.0269
Entamoeba histolytica deoxycytidyl transferase, putative 0.0012 0.0023 0.0313
Toxoplasma gondii cathepsin CPC2 0.0043 0.0268 0.1345
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0012 0.0023 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0058 0.0292
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0068 0.5
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0016 0.0016
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0052 0.0345 0.0345
Schistosoma mansoni cathepsin F (C01 family) 0.0081 0.0577 0.0577
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0225
Schistosoma mansoni nAChR subunit 0.0045 0.0284 0.0284
Loa Loa (eye worm) inositol-1 0.0037 0.0226 0.0386
Toxoplasma gondii cathepsin B 0.0256 0.1992 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0023 0.0107 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.015 0.0751
Onchocerca volvulus 0.0097 0.0706 0.1837
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0117 0.3118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0058 0.0292
Trypanosoma brucei DNA polymerase eta, putative 0.0012 0.0023 0.0115
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0043 0.0268 0.1345
Schistosoma mansoni neurotransmitter gated ion channel 0.0045 0.0284 0.0284
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0268 0.1345
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0196 0.0196
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0118 0.0118
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0269 0.0461
Echinococcus granulosus oncosphere protein Tso22e 0.0105 0.0772 0.0772
Echinococcus granulosus expressed protein 0.0027 0.0137 0.0137
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0045 0.0284 0.0486
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0117 0.3118
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0052 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Leishmania major hypothetical protein, conserved 0.001 0 0.0001
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0097 0.0706 0.0706
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0026 0.0132 0.0226
Giardia lamblia Cathepsin B precursor 0.0256 0.1992 1
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0101 0.2114
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0196 0.0985
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0097 0.0706 0.1208
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0056 0.0056
Trypanosoma brucei cysteine peptidase C (CPC) 0.0256 0.1992 1
Echinococcus multilocularis protein dispatched 1 0.0049 0.0318 0.0318
Giardia lamblia PHD finger protein 15 0.003 0.0162 0.0812
Loa Loa (eye worm) hypothetical protein 0.0476 0.3769 0.6451
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Trypanosoma cruzi cysteine protease, putative 0.0081 0.0577 0.0987
Onchocerca volvulus 0.0081 0.0577 0.1493
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0577 0.7908
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0577 0.1493
Loa Loa (eye worm) hypothetical protein 0.0023 0.0108 0.0185
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0043 0.0268 0.4645
Brugia malayi hypothetical protein 0.0045 0.0284 0.0486
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0027 0.0137 0.0235
Onchocerca volvulus 0.0097 0.0706 0.1837
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0043 0.0268 0.4645
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Echinococcus multilocularis snurportin 1 0.0244 0.1897 0.1897
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0043 0.0268 0.3673
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Brugia malayi hypothetical protein 0.005 0.0329 0.0563
Onchocerca volvulus Alhambra homolog 0.003 0.0162 0.0387
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Plasmodium falciparum JmjC domain-containing protein, putative 0.001 0 0.0002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0267 0.0668
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0097 0.0706 0.0706
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0268 0.0459
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0194 0.9862
Toxoplasma gondii LsmAD domain-containing protein 0.0038 0.0231 0.1158
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Trypanosoma cruzi major cysteine proteinase, putative 0.0043 0.0268 0.0459
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0268 0.1345
Brugia malayi Bromodomain containing protein 0.0032 0.0181 0.031
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0097 0.0706 0.1208
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0544 0.0544
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0577 0.0987
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0081 0.0577 0.0577
Brugia malayi fibroinase precursor 0.0043 0.0268 0.0459
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0097 0.0706 0.1208
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0082 0.0411
Trypanosoma cruzi cysteine proteinase, putative 0.0081 0.0577 0.0987
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0017 0.0059 0.0297
Brugia malayi Intermediate filament tail domain containing protein 0.0021 0.0096 0.0164
Onchocerca volvulus 0.0097 0.0706 0.1837
Toxoplasma gondii histone lysine demethylase JMJD6a 0.001 0 0.0001
Schistosoma mansoni nAChR subunit 0.0097 0.0706 0.0706
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0097 0.0706 0.0706
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0671 0.1148
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0729 0.0729
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.0785 0.1344
Leishmania major cathepsin L-like protease 0.0081 0.0577 0.2895
Echinococcus granulosus snurportin 1 0.0244 0.1897 0.1897
Leishmania major DNA polymerase eta, putative 0.0012 0.0023 0.0115
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Brugia malayi Troponin T 0.005 0.0329 0.0563
Echinococcus granulosus cathepsin b 0.0733 0.5843 0.5843
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0043 0.0268 0.0459
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0342 0.0342
Trypanosoma cruzi ISWI complex protein 0.0016 0.0048 0.0083
Onchocerca volvulus 0.0031 0.0174 0.0419
Loa Loa (eye worm) hypothetical protein 0.0043 0.0268 0.0459
Brugia malayi Troponin family protein 0.0085 0.0608 0.104
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0268 0.1345
Plasmodium vivax vivapain-2 0.0081 0.0577 1
Entamoeba histolytica cysteine protease, putative 0.0081 0.0577 0.7908
Echinococcus granulosus dnaJ subfamily B 0.0325 0.2546 0.2546
Brugia malayi cathepsin Z-like cysteine proteinase 0.0043 0.0268 0.0459
Echinococcus granulosus cathepsin l1 0.0043 0.0268 0.0268
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0729 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0043 0.0268 0.4645
Loa Loa (eye worm) hypothetical protein 0.0097 0.0706 0.1208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0577 0.2895
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0225
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0001 0.0006
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0097 0.0706 0.1208
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0162 0.0162
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0671 0.0671
Schistosoma mansoni chromobox protein 0.0012 0.0016 0.0016
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0269 0.0269
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0268 0.067
Loa Loa (eye worm) ctsf protein 0.0081 0.0577 0.0987
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0041 0.0255 0.3492
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0017 0.0059 0.0059
Leishmania major cathepsin L-like protease 0.0081 0.0577 0.2895
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0081 0.0577 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0016 0.0083
Entamoeba histolytica Ran family GTPase 0.0017 0.0059 0.081
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0097 0.0706 0.0706
Echinococcus granulosus dna polymerase eta 0.0012 0.0023 0.0023
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.0311 0.0311
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0311 0.0311
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0016 0.0083
Entamoeba histolytica cysteine protease, putative 0.0043 0.0268 0.3673
Entamoeba histolytica cysteine protease, putative 0.0043 0.0268 0.3673
Onchocerca volvulus Serine\/threonine kinase homolog 0.0075 0.0532 0.1375
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0097 0.0706 0.0706
Plasmodium vivax vivapain-3 0.0081 0.0577 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0117 0.3118
Brugia malayi SET domain containing protein 0.0013 0.0029 0.005
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0577 0.0987
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0494 0.2478
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0172 0.0171
Brugia malayi hypothetical protein 0.0045 0.0284 0.0486
Echinococcus granulosus Chromo domain 0.0012 0.0016 0.0016
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0011 0.0016 0.0027
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0043 0.0073
Giardia lamblia Cathepsin B precursor 0.0256 0.1992 1
Echinococcus granulosus troponin i 0.0085 0.0608 0.0608
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0101 0.0509
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0081 0.0577 0.0577
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.006 0.2155
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0011 0.0012 0.0214
Schistosoma mansoni hypothetical protein 0.0012 0.0016 0.0016
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0043 0.0268 0.4645
Brugia malayi Bromodomain containing protein 0.0039 0.0237 0.0405
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0577 0.7908
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0268 0.1345
Echinococcus multilocularis oncosphere protein tso22e oncosphere protein tso22d oncosphere protein tso22c oncosphere protein tso22b oncosphere protein tso22 0.0105 0.0772 0.0772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0011 0.0057
Loa Loa (eye worm) hypothetical protein 0.0013 0.0027 0.0047
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0097 0.0706 0.0706
Leishmania major cathepsin L-like protease 0.0081 0.0577 0.2895
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0577 0.2895
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0016 0.0016
Schistosoma mansoni DNA polymerase eta 0.0012 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0083
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0196 0.0335
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0015 0.0042 0.0213
Trichomonas vaginalis CAMK family protein kinase 0.0075 0.0532 0.2673
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0016 0.0285
Loa Loa (eye worm) hypothetical protein 0.0045 0.0284 0.0486
Leishmania major DNA polymerase kappa, putative 0.0015 0.0042 0.0213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0577 0.2895
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0342 0.0586
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0196 0.0985
Loa Loa (eye worm) hypothetical protein 0.0085 0.0608 0.104
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0081 0.0577 0.2895
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0016 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0016 0.0083
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0042 0.0213
Loa Loa (eye worm) hypothetical protein 0.0018 0.0068 0.0117
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0117 0.5443
Echinococcus granulosus lamin 0.0021 0.0096 0.0096
Schistosoma mansoni nAChR subunit 0.0097 0.0706 0.0706
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0097 0.0706 0.1208
Giardia lamblia Cathepsin B precursor 0.0043 0.0268 0.1345
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0101 0.0174
Trypanosoma brucei protein kinase, putative 0.0052 0.0342 0.1719
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0101 0.0509
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0117 0.0588
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0117 0.3118
Echinococcus granulosus zinc finger protein 0.0021 0.0094 0.0094
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0236 0.0236
Schistosoma mansoni troponin I 0.0085 0.0608 0.0608
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0012 0.0023 0.0023
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0097 0.0706 0.0706
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0342 0.1719
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0045 0.0284 0.0486
Schistosoma mansoni gabp alpha 0.0058 0.0387 0.0387
Onchocerca volvulus 0.0012 0.0016 0.00000002729
Plasmodium falciparum serine repeat antigen 3 0.0043 0.0268 0.4645
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0017 0.0061 0.0061
Trichomonas vaginalis hypothetical protein 0.0012 0.0016 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0268 0.1345
Loa Loa (eye worm) hypothetical protein 0.0052 0.0345 0.059
Trypanosoma cruzi importin beta-1 subunit, putative 0.0019 0.0073 0.0125
Onchocerca volvulus 0.0081 0.0577 0.1493
Leishmania major cysteine peptidase A (CPA) 0.0081 0.0577 0.2895
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0097 0.0706 0.1208
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0729 0.1248

Activities

Activity type Activity value Assay description Source Reference
Minimal bacteriostatic concentration (functional) 0 Minimal bacteriostatic concentration against streptococcus pyogenes under conditions of pH 7.3, 37 degree C; 1 in <5000 ChEMBL. 6979630

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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