Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.0275 | 0.0805 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.002 | 0.0175 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0055 |
Brugia malayi | CCR4 | 0.0009 | 0.0003 | 0.0028 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.002 | 0.0175 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.1182 | 0.6219 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.002 | 0.0175 |
Plasmodium vivax | hypothetical protein, conserved | 0.0009 | 0.0003 | 0.0044 |
Trypanosoma cruzi | DNA topoisomerase type IB small subunit, putative | 0.0031 | 0.0122 | 0.0782 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.05 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0003 | 0.0028 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0005 | 0.0047 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0032 | 0.0129 | 0.0207 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase domain containing protein | 0.0009 | 0.0003 | 0.0021 |
Mycobacterium ulcerans | beta-lactamase | 0.0032 | 0.0129 | 0.0207 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0104 | 0.0912 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0005 | 0.0016 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0021 | 0.0067 | 0.0107 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0009 | 0.0003 | 0.0028 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0155 | 0.0779 | 0.682 |
Onchocerca volvulus | 0.0047 | 0.0205 | 1 | |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0018 | 0.0055 | 0.0055 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.002 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0067 | 0.0587 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0054 | 0.0242 | 0.2185 |
Brugia malayi | Deoxynucleoside kinase family protein | 0.0085 | 0.0407 | 0.3563 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.002 | 0.0058 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.002 | 0.0175 |
Mycobacterium ulcerans | hypothetical protein | 0.0032 | 0.0129 | 0.0207 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0049 | 0.0217 | 0.1903 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.0379 | 0.1965 | 0.5753 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.0033 | 0.0212 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0043 | 0.0184 | 0.0539 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0008 | 0.0001 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0175 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.002 | 0.0058 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0009 | 0.0003 | 0.0028 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0009 | 0.0003 | 0.0021 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0137 | 0.0879 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0009 | 0.0003 | 0.0003 |
Echinococcus granulosus | GPCR family 2 | 0.0049 | 0.0217 | 0.0637 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0028 | 0.0104 | 0.0167 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.002 | 0.0058 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0032 | 0.0129 | 0.0207 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0001 | 0.0004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0043 | 0.0184 | 0.1643 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.002 | 0.0175 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0021 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0043 | 0.0184 | 0.0296 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0028 | 0.0104 | 0.0167 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.002 | 0.0175 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.002 | 0.0175 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0079 | 0.0507 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.002 | 0.002 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0012 | 0.002 | 0.0951 |
Brugia malayi | DNA topoisomerase I | 0.0123 | 0.0611 | 0.5344 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0301 | 0.1554 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.002 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0175 |
Entamoeba histolytica | inositol polyphosphate 5-phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0018 | 0.0055 | 0.0355 |
Leishmania major | thymidine kinase, putative | 0.0301 | 0.1554 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0217 | 0.0217 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0137 | 0.0879 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0217 | 0.1105 | 0.1777 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0912 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0653 | 0.3416 | 0.3416 |
Plasmodium vivax | endonuclease/exonuclease/phosphatase domain containing protein | 0.0009 | 0.0003 | 0.0044 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0008 | 0.0001 | 0.0004 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.05 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.002 | 0.0058 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0204 | 0.0598 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0113 | 0.0985 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0032 | 0.0129 | 0.0129 |
Leishmania major | inositol phosphosphingolipid phospholipase C-Like | 0.0009 | 0.0003 | 0.0017 |
Giardia lamblia | Thymidine kinase | 0.0301 | 0.1554 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0217 | 0.0637 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0129 | 0.0833 |
Echinococcus multilocularis | thymidine kinase | 0.0379 | 0.1965 | 0.1965 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0061 | 0.0097 |
Echinococcus granulosus | neutral sphingomyelinase | 0.0009 | 0.0003 | 0.0009 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0028 | 0.0104 | 0.0671 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0001 | 0.0004 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0217 | 0.1105 | 0.1777 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0009 | 0.0003 | 0.0028 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0043 | 0.0184 | 0.1186 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0043 | 0.0184 | 0.1186 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.0003 | 0.0017 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0085 | 0.0407 | 0.262 |
Onchocerca volvulus | 0.0029 | 0.0113 | 0.5469 | |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0009 | 0.0003 | 0.0021 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0029 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0061 | 0.0097 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0483 |
Loa Loa (eye worm) | deoxynucleoside kinase | 0.0085 | 0.0407 | 0.3563 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0137 | 0.0879 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0085 | 0.0407 | 0.262 |
Echinococcus multilocularis | deoxyribonuclease 1 2 | 0.0009 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0175 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0043 | 0.0184 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0205 | 0.1797 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0032 | 0.0129 | 0.0833 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0125 | 0.0804 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.002 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0175 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0224 | 0.1143 | 0.1143 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0301 | 0.1554 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0217 | 0.0637 |
Echinococcus granulosus | synaptojanin 1 | 0.0009 | 0.0003 | 0.0009 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0032 | 0.0129 | 0.0207 |
Schistosoma mansoni | hypothetical protein | 0.0009 | 0.0003 | 0.0009 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.002 | 0.0058 |
Trypanosoma cruzi | DNA topoisomerase IB, large subunit, putative | 0.0092 | 0.0446 | 0.2873 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0079 | 0.0507 |
Giardia lamblia | Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative | 0.0085 | 0.0407 | 0.2605 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.1143 | 1 |
Trypanosoma cruzi | mitochondrial protein 99, putative | 0.0009 | 0.0003 | 0.0021 |
Brugia malayi | RNA recognition motif domain containing protein | 0.006 | 0.0275 | 0.2406 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0009 | 0.0003 | 0.0021 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0029 |
Onchocerca volvulus | 0.0012 | 0.002 | 0.0951 | |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0121 | 0.0355 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.002 | 0.0175 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0014 | 0.0033 | 0.0033 |
Mycobacterium ulcerans | lipase LipD | 0.0032 | 0.0129 | 0.0207 |
Plasmodium vivax | topoisomerase I, putative | 0.0123 | 0.0611 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0049 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0129 | 0.1132 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0175 |
Schistosoma mansoni | synaptojanin | 0.0009 | 0.0003 | 0.0009 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0032 | 0.0129 | 0.1132 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0009 | 0.0003 | 0.0021 |
Echinococcus granulosus | dnaJ subfamily B | 0.0417 | 0.2166 | 0.6342 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0029 |
Trypanosoma brucei | DNA topoisomerase IB, large subunit | 0.0092 | 0.0446 | 0.2873 |
Toxoplasma gondii | propionate-CoA ligase | 0.0008 | 0.0001 | 0.0005 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0028 | 0.0104 | 0.0167 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0204 | 0.0598 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.0275 | 0.0805 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0067 | 0.0587 |
Entamoeba histolytica | sphingomyelinase C precursor, putative | 0.0009 | 0.0003 | 0.0021 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0043 | 0.0183 | 0.0535 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0043 | 0.0184 | 0.1613 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0092 | 0.0446 | 0.1307 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0301 | 0.1554 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0003 | 0.0028 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0121 | 0.0355 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0129 | 0.1132 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0242 | 0.2114 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0009 | 0.0003 | 0.0021 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0009 | 0.0003 | 0.0021 |
Echinococcus granulosus | inositol polyphosphate 5 phosphatase OCRL 1 | 0.0009 | 0.0003 | 0.0009 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.0519 | 0.152 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.0275 | 0.0805 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0014 | 0.0033 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0001 | 0.0004 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0001 | 0.0004 |
Mycobacterium tuberculosis | Conserved protein | 0.0032 | 0.0129 | 0.0207 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0043 | 0.0183 | 0.1172 |
Schistosoma mansoni | ocrl type II inositol 5-phosphatase | 0.0009 | 0.0003 | 0.0009 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0008 | 0.0001 | 0.0004 |
Giardia lamblia | Hypothetical protein | 0.0085 | 0.0407 | 0.2605 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0129 | 0.1132 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.002 | 0.0058 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0034 | 0.0137 | 0.0877 |
Echinococcus multilocularis | thymidine kinase | 0.0379 | 0.1965 | 0.1965 |
Loa Loa (eye worm) | beta-lactamase | 0.0032 | 0.0129 | 0.1132 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0021 | 0.0067 | 0.0107 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0199 | 0.0583 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0204 | 0.0598 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Echinococcus multilocularis | synaptojanin 1 | 0.0009 | 0.0003 | 0.0003 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.002 | 0.002 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0125 | 0.0804 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0079 | 0.0508 |
Brugia malayi | isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0483 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0129 | 0.1132 |
Leishmania major | hypothetical protein, conserved | 0.0032 | 0.0129 | 0.083 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Brugia malayi | RNA binding protein | 0.006 | 0.0275 | 0.2406 |
Echinococcus granulosus | thymidine kinase | 0.0379 | 0.1965 | 0.5753 |
Loa Loa (eye worm) | DNA topoisomerase I | 0.0123 | 0.0611 | 0.5344 |
Plasmodium vivax | exodeoxyribonuclease III, putative | 0.0009 | 0.0003 | 0.0044 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.0242 | 0.1554 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0029 |
Mycobacterium tuberculosis | Conserved protein | 0.0032 | 0.0129 | 0.0207 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0104 | 0.0167 |
Leishmania major | DNA topoisomerase IB, large subunit | 0.0092 | 0.0446 | 0.2871 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0043 | 0.0183 | 0.1175 |
Brugia malayi | TAR-binding protein | 0.006 | 0.0275 | 0.2406 |
Schistosoma mansoni | nocturnin | 0.0009 | 0.0003 | 0.0009 |
Plasmodium falciparum | topoisomerase I | 0.0123 | 0.0611 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.002 | 0.0058 |
Schistosoma mansoni | hypothetical protein | 0.0417 | 0.2166 | 0.6342 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.0003 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0003 | 0.0029 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0092 | 0.0592 |
Mycobacterium ulcerans | molybdopterin-guanine dinucleotide biosynthesis protein A | 0.0217 | 0.1105 | 0.1777 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0032 | 0.0129 | 0.0379 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.002 | 0.0175 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0204 | 0.1789 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Echinococcus multilocularis | transfer RNA-Ile | 0.0379 | 0.1965 | 0.1965 |
Trichomonas vaginalis | type II inositol 5-phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0043 | 0.0184 | 0.1183 |
Trichomonas vaginalis | type IV inositol 5-phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.002 | 0.0175 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0009 | 0.0003 | 0.0009 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0043 | 0.0184 | 0.1186 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0028 | 0.0104 | 0.0167 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0104 | 0.0912 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.002 | 0.0058 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0001 | 0.0004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0204 | 0.0598 |
Giardia lamblia | GTOR | 0.0043 | 0.0183 | 0.1157 |
Toxoplasma gondii | non-specific serine/threonine protein kinase | 0.0009 | 0.0005 | 0.0044 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0021 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.002 | 0.0175 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Schistosoma mansoni | NADH-ubiquinone oxidoreductase | 0.0085 | 0.0407 | 0.1192 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0043 | 0.0184 | 0.3012 |
Plasmodium falciparum | exodeoxyribonuclease III, putative | 0.0009 | 0.0003 | 0.0044 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0032 | 0.0129 | 0.0207 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0061 | 0.0097 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.002 | 0.0175 |
Leishmania major | pantothenate kinase subunit, putative | 0.001 | 0.0009 | 0.0056 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0092 | 0.0446 | 0.1307 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0009 | 0.0003 | 0.0028 |
Schistosoma mansoni | cript-related | 0.0009 | 0.0003 | 0.0009 |
Echinococcus multilocularis | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.0085 | 0.0407 | 0.0407 |
Onchocerca volvulus | 0.0032 | 0.0129 | 0.6294 | |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0043 | 0.0184 | 0.0184 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.002 | 0.0058 |
Plasmodium falciparum | endonuclease/exonuclease/phosphatase family protein, putative | 0.0009 | 0.0003 | 0.0044 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0032 | 0.0129 | 0.0207 |
Loa Loa (eye worm) | TAR-binding protein | 0.006 | 0.0275 | 0.2406 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0519 | 0.4544 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0207 | 0.1056 | 0.1698 |
Loa Loa (eye worm) | endonuclease/Exonuclease/phosphatase | 0.0009 | 0.0003 | 0.0028 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0032 | 0.0129 | 0.0207 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0028 | 0.0104 | 0.0167 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0012 | 0.002 | 0.002 |
Brugia malayi | beta-lactamase family protein | 0.0032 | 0.0129 | 0.1132 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.002 | 0.0058 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0049 | 0.0217 | 0.1903 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0024 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | oxidoreductase | 0.0008 | 0.0001 | 0.0004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0129 | 0.0833 |
Plasmodium vivax | hypothetical protein, conserved | 0.0032 | 0.0129 | 0.2112 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0012 | 0.002 | 0.0951 |
Echinococcus multilocularis | tar DNA binding protein | 0.006 | 0.0275 | 0.0275 |
Trypanosoma brucei | DNA topoisomerase type IB small subunit | 0.0031 | 0.0122 | 0.0782 |
Trypanosoma cruzi | inositol 5-phosphatase 1, putative | 0.0009 | 0.0003 | 0.0021 |
Brugia malayi | hypothetical protein | 0.0224 | 0.1143 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.015 | 0.0963 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0021 | 0.0067 | 0.1091 |
Mycobacterium tuberculosis | Probable exported protein | 0.0009 | 0.0003 | 0.0004 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0021 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0092 | 0.0592 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0141 | 0.1233 |
Trichomonas vaginalis | sphingomyelinase C 2 precursor, putative | 0.0009 | 0.0003 | 0.0021 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0155 | 0.0779 | 0.682 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0217 | 0.0637 |
Onchocerca volvulus | 0.0032 | 0.0129 | 0.6294 | |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.002 | 0.0058 |
Onchocerca volvulus | 0.0009 | 0.0003 | 0.0132 | |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0085 | 0.0407 | 0.262 |
Trichomonas vaginalis | skeletal muscle/kidney enriched inositol 5-phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0106 | 0.0519 | 0.4544 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0043 | 0.0184 | 0.1186 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0018 | 0.0055 | 0.0088 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0175 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0009 | 0.0003 | 0.0044 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0008 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0014 | 0.0033 | 0.0288 |
Brugia malayi | Isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0483 |
Trypanosoma cruzi | pantothenate kinase subunit, putative | 0.001 | 0.0009 | 0.0059 |
Toxoplasma gondii | exonuclease III APE | 0.0043 | 0.0184 | 0.1667 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.002 | 0.0175 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0014 | 0.0033 | 0.0288 |
Loa Loa (eye worm) | CCR4-NOT transcription complex subunit 6 family protein | 0.0009 | 0.0003 | 0.0028 |
Mycobacterium ulcerans | hypothetical protein | 0.0217 | 0.1105 | 0.1777 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0009 | 0.0003 | 0.0021 |
Trichomonas vaginalis | Phospholipase C precursor, putative | 0.0009 | 0.0003 | 0.0021 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0009 | 0.0003 | 0.0021 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.002 | 0.002 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0121 | 0.0121 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0009 | 0.0003 | 0.0021 |
Mycobacterium tuberculosis | Conserved protein | 0.0032 | 0.0129 | 0.0207 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.002 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0067 | 0.0587 |
Mycobacterium ulcerans | hypothetical protein | 0.0028 | 0.0104 | 0.0167 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0104 | 0.0167 |
Leishmania major | RNA-editing complex protein MP100, putative | 0.0009 | 0.0003 | 0.0017 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0104 | 0.0668 |
Echinococcus granulosus | DNA topoisomerase 1 | 0.0123 | 0.0611 | 0.1787 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.002 | 0.0175 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0024 | 0.0085 | 0.0248 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0121 | 0.0355 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0008 | 0.0001 | 0.0004 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0054 | 0.0242 | 0.3951 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0204 | 0.0204 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0125 | 0.0804 |
Trypanosoma brucei | RNA editing exonuclease 2 | 0.0009 | 0.0003 | 0.0021 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0204 | 0.1789 |
Plasmodium falciparum | carbon catabolite repressor protein 4, putative | 0.0009 | 0.0003 | 0.0044 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.002 | 0.0064 | 0.0411 |
Trypanosoma brucei | Inositol phosphosphingolipids phospholipase C | 0.0009 | 0.0003 | 0.0021 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0032 | 0.0129 | 0.0379 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0028 | 0.0104 | 0.0167 |
Echinococcus multilocularis | neutral sphingomyelinase | 0.0009 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0005 | 0.0043 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0137 | 0.0879 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0005 | 0.0042 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.002 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0175 |
Trypanosoma cruzi | Endonuclease/Exonuclease/phosphatase family, putative | 0.0009 | 0.0003 | 0.0021 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0043 | 0.0183 | 0.1175 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0018 | 0.0055 | 0.0897 |
Schistosoma mansoni | ap endonuclease | 0.0043 | 0.0184 | 0.0539 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0043 | 0.0184 | 0.1613 |
Echinococcus granulosus | NADH ubiquinone oxidoreductase 42 kDa subunit | 0.0085 | 0.0407 | 0.1192 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0.0001 | 0.0003 |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.002 | 0.0175 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.0033 | 0.0212 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.002 | 0.0058 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.002 | 0.0175 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0.0001 | 0.0003 |
Trypanosoma cruzi | endonuclease/exonuclease/phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.002 | 0.0175 |
Onchocerca volvulus | 0.0046 | 0.0199 | 0.97 | |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.002 | 0.002 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0032 | 0.0129 | 0.1132 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0014 | 0.0033 | 0.0212 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0018 | 0.0055 | 0.0897 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0301 | 0.1554 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0242 | 0.2114 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.0779 | 0.682 |
Brugia malayi | beta-lactamase | 0.0032 | 0.0129 | 0.1132 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0217 | 0.0637 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0104 | 0.0667 |
Leishmania major | inositol/phosphatidylinositol phosphatase, putative | 0.0009 | 0.0003 | 0.0017 |
Schistosoma mansoni | thymidine kinase | 0.0379 | 0.1965 | 0.5753 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0286 | 0.0838 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.002 | 0.0175 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0054 | 0.0242 | 0.1554 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0067 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0001 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.0275 | 0.0805 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0123 | 0.0611 | 0.1787 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0301 | 0.1554 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.002 | 0.0058 |
Mycobacterium leprae | Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU | 0.1182 | 0.6219 | 1 |
Echinococcus multilocularis | inositol polyphosphate 5 phosphatase OCRL 1 | 0.0009 | 0.0003 | 0.0003 |
Trypanosoma cruzi | mitochondrial protein 99, putative | 0.0009 | 0.0003 | 0.0021 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0032 | 0.0129 | 0.0207 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0104 | 0.0668 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0043 | 0.0183 | 0.1175 |
Brugia malayi | beta-lactamase family protein | 0.0032 | 0.0129 | 0.1132 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.0033 | 0.0212 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0021 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0043 | 0.0183 | 0.0535 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.002 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0003 | 0.0028 |
Leishmania major | endonuclease/exonuclease protein-like protein | 0.0009 | 0.0003 | 0.0017 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0079 | 0.0508 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0054 | 0.0242 | 0.3951 |
Schistosoma mansoni | neutral sphingomyelinase | 0.0009 | 0.0003 | 0.0009 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0049 | 0.0217 | 0.1903 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0043 | 0.0183 | 0.0183 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0009 | 0.0003 | 0.0021 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0034 | 0.0137 | 0.0879 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0029 |
Schistosoma mansoni | carbon catabolite repressor protein | 0.0009 | 0.0003 | 0.0009 |
Echinococcus multilocularis | DNA topoisomerase 1 | 0.0123 | 0.0611 | 0.0611 |
Plasmodium vivax | endonuclease/exonuclease/phosphatase domain containing protein | 0.0009 | 0.0003 | 0.0044 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.006 | 0.0275 | 0.2406 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0912 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0162 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0014 | 0.0033 | 0.0096 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase domain containing protein | 0.0009 | 0.0003 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0067 | 0.0587 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Trypanosoma brucei | Endonuclease/Exonuclease/phosphatase family, putative | 0.0009 | 0.0003 | 0.0021 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0018 | 0.0115 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.002 | 0.0175 |
Schistosoma mansoni | tar DNA-binding protein | 0.006 | 0.0275 | 0.0805 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0008 | 0.0001 | 0.0001 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0005 | 0.0005 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.002 | 0.0058 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0014 | 0.0033 | 0.0212 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0028 | 0.0104 | 0.0668 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0129 | 0.0833 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0055 | 0.0352 |
Toxoplasma gondii | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0029 |
Trypanosoma brucei | inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0012 | 0.002 | 0.0951 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0021 | 0.0067 | 0.1091 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0014 | 0.0033 | 0.0096 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0008 | 0.0001 | 0.0003 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0043 | 0.0184 | 0.1186 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0129 | 0.0833 |
Schistosoma mansoni | synaptojanin | 0.0009 | 0.0003 | 0.0009 |
Trypanosoma cruzi | RNA-editing complex protein MP100, putative | 0.0009 | 0.0003 | 0.0021 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0028 | 0.0104 | 0.0167 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0055 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0032 | 0.0129 | 0.0379 |
Onchocerca volvulus | 0.0032 | 0.0129 | 0.6294 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0043 | 0.0184 | 0.3012 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0.0001 | 0.0003 |
Echinococcus multilocularis | tumor protein p63 | 0.032 | 0.1651 | 0.1651 |
Trypanosoma cruzi | Inositol phosphosphingolipids phospholipase C | 0.0009 | 0.0003 | 0.0021 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0061 | 0.0097 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0162 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0043 | 0.0183 | 0.1598 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0034 | 0.0137 | 0.088 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0043 | 0.0183 | 0.1175 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0129 | 0.1132 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0032 | 0.0129 | 0.0207 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0014 | 0.0033 | 0.0209 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0021 | 0.0067 | 0.5 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0055 | 0.0355 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0043 | 0.0183 | 0.1175 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0417 | 0.2166 | 0.2166 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.002 | 0.0058 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0021 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0032 | 0.0129 | 0.0833 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0653 | 0.3416 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0204 | 0.0204 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0046 | 0.0199 | 0.1743 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.002 | 0.0175 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0085 | 0.0407 | 0.262 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0217 | 0.0637 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0079 | 0.0508 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0018 | 0.0051 | 0.0328 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.002 | 0.002 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.0055 | 0.0355 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0653 | 0.3416 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.002 | 0.0175 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0091 | 0.0583 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0008 | 0.0001 | 0.0003 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0018 | 0.0055 | 0.0355 |
Leishmania major | hypothetical protein, conserved | 0.0009 | 0.0003 | 0.0017 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0008 | 0.0001 | 0.0003 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.002 | 0.0058 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0043 | 0.0183 | 0.1175 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0224 | 0.1143 | 0.3345 |
Echinococcus multilocularis | traf and tnf receptor associated protein | 0.0009 | 0.0003 | 0.0003 |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.002 | 0.0175 |
Toxoplasma gondii | DNA topoisomerase I, putative | 0.0123 | 0.0611 | 0.5524 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0125 | 0.0804 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.002 | 0.0175 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0125 | 0.0804 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.002 | 0.0175 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0113 | 0.0329 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0032 | 0.0129 | 0.0207 |
Onchocerca volvulus | 0.0009 | 0.0003 | 0.0132 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0079 | 0.0507 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0009 | 0.0005 | 0.0031 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.002 | 0.002 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0104 | 0.0912 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0054 | 0.0242 | 0.3951 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0043 | 0.0183 | 0.1175 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.0242 | 0.1554 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0175 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0125 | 0.0804 |
Onchocerca volvulus | Putative neutral sphingomyelinase | 0.0009 | 0.0003 | 0.0132 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0091 | 0.0583 |
Entamoeba histolytica | endonuclease/exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0021 |
Entamoeba histolytica | thymidine kinase, putative | 0.0301 | 0.1554 | 1 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0043 | 0.0183 | 0.1172 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0113 | 0.0985 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0043 | 0.0183 | 0.1598 |
Echinococcus granulosus | traf and tnf receptor associated protein | 0.0009 | 0.0003 | 0.0009 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0014 | 0.0033 | 0.0212 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0032 | 0.0129 | 0.0833 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0008 | 0.0001 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0104 | 0.0912 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Toxoplasma gondii | eukaryotic initiation factor-2B, gamma subunit, putative | 0.0217 | 0.1105 | 1 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0.0001 | 0.0003 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0043 | 0.0184 | 0.1168 |
Leishmania major | DNA topoisomerase type IB small subunit | 0.0031 | 0.0122 | 0.0779 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0092 | 0.0592 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0217 | 0.0217 |
Echinococcus granulosus | CCR4 NOT transcription complex subunit 6 | 0.0009 | 0.0003 | 0.0009 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0043 | 0.0184 | 0.1186 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0032 | 0.0129 | 0.0833 |
Plasmodium falciparum | DNase I-like protein, putative | 0.0009 | 0.0003 | 0.0044 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.002 | 0.0058 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0108 | 0.0698 |
Schistosoma mansoni | survival motor neuron protein | 0.0046 | 0.0199 | 0.0583 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.0033 | 0.0212 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.0055 | 0.0055 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU | 0.1182 | 0.6219 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0085 | 0.0248 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0009 | 0.0003 | 0.0021 |
Mycobacterium ulcerans | bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase | 0.1182 | 0.6219 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0125 | 0.0804 |
Schistosoma mansoni | ap endonuclease | 0.0043 | 0.0184 | 0.0539 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.002 | 0.0058 |
Trichomonas vaginalis | esterase, putative | 0.0032 | 0.0129 | 0.0833 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0008 | 0.0001 | 0.0001 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0014 | 0.0033 | 0.0212 |
Trypanosoma brucei | inositol/phosphatidylinositol phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Trypanosoma brucei | thymidine kinase | 0.0301 | 0.1554 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0032 | 0.0129 | 0.0207 |
Echinococcus granulosus | tumor protein p63 | 0.032 | 0.1651 | 0.4833 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0043 | 0.0183 | 0.1175 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0047 | 0.0205 | 0.0601 |
Trichomonas vaginalis | ocrl type II inositol 5-phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Treponema pallidum | licC protein (licC) | 0.0217 | 0.1105 | 1 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0034 | 0.0137 | 0.088 |
Onchocerca volvulus | 0.0028 | 0.0104 | 0.5064 | |
Echinococcus granulosus | tar DNA binding protein | 0.006 | 0.0275 | 0.0805 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0155 | 0.0779 | 0.682 |
Giardia lamblia | Hypothetical protein | 0.0085 | 0.0407 | 0.2605 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0251 | 0.2273 |
Entamoeba histolytica | hypothetical protein | 0.0085 | 0.0407 | 0.262 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0008 | 0.0001 | 0.0005 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.002 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0217 | 0.1903 |
Trypanosoma brucei | DNA-(apurinic or apyrimidinic site) lyase, putative | 0.0009 | 0.0003 | 0.0021 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0023 | 0.0079 | 0.0508 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Giardia lamblia | Deoxynucleoside kinase | 0.0085 | 0.0407 | 0.2605 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0014 | 0.0033 | 0.0209 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0028 | 0.0104 | 0.0671 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0008 | 0.0001 | 0.0003 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0028 | 0.0104 | 0.0167 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.002 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0129 | 0.1132 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0003 | 0.0028 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0204 | 0.0598 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0217 | 0.0637 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.002 | 0.0058 |
Toxoplasma gondii | ABC1 family protein | 0.0032 | 0.0129 | 0.117 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.002 | 0.002 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0028 | 0.0104 | 0.0167 |
Leishmania major | hypothetical protein, conserved | 0.0054 | 0.0242 | 0.1551 |
Entamoeba histolytica | inositol polyphosphate-5-phosphatase, putative | 0.0009 | 0.0003 | 0.0021 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0009 | 0.0003 | 0.0028 |
Echinococcus granulosus | thymidine kinase | 0.0379 | 0.1965 | 0.5753 |
Mycobacterium ulcerans | hypothetical protein | 0.0217 | 0.1105 | 0.1777 |
Echinococcus multilocularis | CCR4 NOT transcription complex subunit 6 | 0.0009 | 0.0003 | 0.0003 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0043 | 0.0183 | 0.1175 |
Loa Loa (eye worm) | RNA binding protein | 0.006 | 0.0275 | 0.2406 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0028 | 0.0104 | 0.0671 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0008 | 0.0001 | 0.0001 |
Mycobacterium leprae | conserved hypothetical protein | 0.0032 | 0.0129 | 0.0207 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0032 | 0.0125 | 0.113 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Differential affinity (binding) | = 0.91 | Differential affinity is the ratio between M-TK and C-TK | ChEMBL. | 7097717 |
Differential affinity (binding) | = 1.8 | Differential affinity is the ratio between M-TK and C-TK | ChEMBL. | 7097717 |
Ki (binding) | = 0.002 mM | Competitive inhibition against rat cytoplasmic Thymidine kinase | ChEMBL. | 7097717 |
Ki (binding) | = 0.0039 mM | Competitive inhibition against rat cytoplasmic Thymidine kinase | ChEMBL. | 7097717 |
Ki (binding) | = 0.011 mM | Competitive inhibition against rat mitochondrial thymidine kinase | ChEMBL. | 7097717 |
Relative affinity (binding) | = 0.41 | Affinity towards cytoplasmic Thymidine kinase relative ot TdR. | ChEMBL. | 7097717 |
Relative affinity (binding) | = 0.73 | Affinity towards mitochondrial thymidine kinase relative to TdR. | ChEMBL. | 7097717 |
Relative affinity (binding) | = 0.8 | Affinity towards cytoplasmic Thymidine kinase relative ot TdR. | ChEMBL. | 7097717 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.