Detailed information for compound 286927

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 362.505 | Formula: C25H30O2
  • H donors: 2 H acceptors: 2 LogP: 5.58 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c(c1)C[C@H](C1C2CCC2(C1CCC2O)C)Cc1ccccc1
  • InChi: 1S/C25H30O2/c1-25-12-11-21-20-8-7-19(26)15-17(20)14-18(13-16-5-3-2-4-6-16)24(21)22(25)9-10-23(25)27/h2-8,15,18,21-24,26-27H,9-14H2,1H3/t18-,21?,22?,23?,24?,25?/m1/s1
  • InChiKey: VBLWCYNQWREDNM-GVLFCTMHSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni phosphoserine phosphatase 0.0151 0.0061 0.075
Entamoeba histolytica hypothetical protein 0.058 0.0332 0.4399
Trichomonas vaginalis PIKK family atypical protein kinase 0.1205 0.0726 1
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0772 0.0453 0.0444
Loa Loa (eye worm) hypothetical protein 0.009 0.0022 0.0301
Loa Loa (eye worm) hypothetical protein 0.0809 0.0476 0.6511
Schistosoma mansoni hypothetical protein 0.0104 0.0031 0.0339
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0254 0.0126 0.0362
Schistosoma mansoni phospholipid-transporting atpase 0.0091 0.0023 0.0231
Echinococcus multilocularis serine protein kinase ATM 0.0684 0.0397 0.0389
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0772 0.0453 0.6119
Brugia malayi larval opioid receptor 0.0104 0.0031 0.0416
Echinococcus granulosus tm gpcr rhodopsin 0.0104 0.0031 0.0022
Entamoeba histolytica alcohol dehydrogenase, putative 0.0104 0.0031 0.0126
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0239 0.0116 0.1349
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0772 0.0453 0.0444
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0771 0.0452 0.6225
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.046 0.0256 0.0247
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0621 0.0357 0.0349
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0241 0.0118 0.2852
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0104 0.0031 0.0127
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0104 0.0031 0.0022
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1205 0.0726 0.2007
Onchocerca volvulus 0.1213 0.0731 1
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0239 0.0116 0.0334
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0104 0.0031 0.0339
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.046 0.0256 0.3462
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0621 0.0357 0.479
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0104 0.0031 0.0339
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0239 0.0116 0.1597
Schistosoma mansoni histamine h1 receptor 0.0104 0.0031 0.0339
Onchocerca volvulus 0.0104 0.0031 0.0123
Entamoeba histolytica aldose reductase, putative 0.0358 0.0192 0.2408
Schistosoma mansoni phospholipid-transporting atpase 0.009 0.0022 0.022
Loa Loa (eye worm) cytochrome P450 family protein 0.0116 0.0039 0.0526
Schistosoma mansoni amine GPCR 0.0104 0.0031 0.0339
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.0809 0.0476 0.6511
Echinococcus multilocularis g protein coupled receptor 0.0104 0.0031 0.0022
Loa Loa (eye worm) hypothetical protein 0.0248 0.0122 0.167
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0104 0.0031 0.0022
Trypanosoma brucei aldo/keto reductase, putative 0.0104 0.0031 0.0425
Echinococcus multilocularis allatostatin A receptor 0.0104 0.0031 0.0022
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0292 0.015 0.206
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0104 0.0031 0.042
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1205 0.0726 0.0718
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0104 0.0031 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0031 0.0126
Echinococcus multilocularis neuropeptide receptor 0.0104 0.0031 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.1184 0.0713 0.9807
Loa Loa (eye worm) hypothetical protein 0.0373 0.0201 0.2743
Schistosoma mansoni biogenic amine receptor 0.0104 0.0031 0.0339
Plasmodium falciparum copper-transporting ATPase 0.0241 0.0118 0.2218
Schistosoma mansoni phospholipid-transporting atpase 0.0091 0.0023 0.0231
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0241 0.0118 0.1619
Loa Loa (eye worm) phosphatidylinositol 3 0.0239 0.0116 0.1586
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0292 0.015 0.1812
Echinococcus granulosus peptide allatostatin:somatostatin 0.0104 0.0031 0.0022
Toxoplasma gondii aldo-keto reductase 0.0104 0.0031 0.0127
Echinococcus multilocularis neuropeptide Y receptor 0.0104 0.0031 0.0022
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0771 0.0452 0.6107
Brugia malayi E1-E2 ATPase family protein 0.0241 0.0118 0.159
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0241 0.0118 0.0109
Trichomonas vaginalis cation-transporting ATPase, putative 0.0091 0.0023 0.0012
Loa Loa (eye worm) TYRA-2 protein 0.0104 0.0031 0.042
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0292 0.015 0.0413
Trichomonas vaginalis PIKK family atypical protein kinase 0.1193 0.0719 0.9893
Trichomonas vaginalis aldo/keto reductase, putative 0.0358 0.0192 0.2408
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Trypanosoma cruzi cation-transporting ATPase, putative 0.0241 0.0118 0.0339
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1205 0.0726 0.2094
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0104 0.0031 0.0022
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0358 0.0192 0.5761
Plasmodium falciparum aldehyde reductase, putative 0.0104 0.0031 0.0206
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0091 0.0023 0.0012
Leishmania major cation-transporting ATPase, putative 0.009 0.0022 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0104 0.0031 0.0022
Brugia malayi Na,K-ATPase alpha subunit 0.0795 0.0468 0.6319
Loa Loa (eye worm) oxidoreductase 0.0358 0.0192 0.262
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.058 0.0332 0.4399
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0241 0.0118 0.3109
Brugia malayi NADH-dependent xylose reductase 0.0104 0.0031 0.0418
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Schistosoma mansoni type V p-type atpase isoform 0.0091 0.0023 0.0231
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0104 0.0031 0.0339
Echinococcus multilocularis voltage gated potassium channel subunit 0.0104 0.0031 0.0022
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0091 0.0023 0.0314
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0241 0.0118 0.2852
Schistosoma mansoni neuropeptide receptor 0.0104 0.0031 0.0339
Leishmania major aldo-keto reductase-like protein 0.0358 0.0192 0.0529
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.0338 0.0179 0.2445
Echinococcus multilocularis serotonin receptor 0.0809 0.0476 0.0467
Echinococcus granulosus neuropeptide receptor 0.0104 0.0031 0.0022
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1226 0.074 0.0731
Leishmania major calcium-translocating P-type ATPase 0.0771 0.0452 0.1249
Trichomonas vaginalis PIKK family atypical protein kinase 0.1195 0.072 0.9914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0241 0.0118 0.2521
Echinococcus multilocularis g protein coupled receptor 0.0104 0.0031 0.0022
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0684 0.0397 0.5372
Trypanosoma brucei calcium-translocating P-type ATPase 0.0621 0.0357 0.4921
Schistosoma mansoni amine GPCR 0.0104 0.0031 0.0339
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0241 0.0118 0.1357
Brugia malayi Dopamine receptor protein 2 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.1193 0.0719 0.9893
Leishmania major P-type ATPase, putative 0.0621 0.0357 0.0987
Trypanosoma brucei cation-transporting ATPase, putative 0.0241 0.0118 0.1619
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0621 0.0357 0.4831
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0621 0.0357 0.479
Trichomonas vaginalis PIKK family atypical protein kinase 0.1184 0.0713 0.9807
Onchocerca volvulus 0.0104 0.0031 0.0123
Loa Loa (eye worm) calcium ATPase 0.009 0.0022 0.0301
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0104 0.0031 0.0022
Mycobacterium tuberculosis Probable oxidoreductase 0.0358 0.0192 0.5285
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0794 0.0467 1
Brugia malayi RE15519p 0.0104 0.0031 0.0416
Schistosoma mansoni amine GPCR 0.0104 0.0031 0.0339
Loa Loa (eye worm) hypothetical protein 0.0248 0.0122 0.167
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0104 0.0031 0.042
Brugia malayi Melatonin receptor type 1A 0.0104 0.0031 0.0416
Echinococcus multilocularis cation transporting ATPase 13A1 0.0241 0.0118 0.0109
Echinococcus granulosus 7TM GPCR rhodopsin 0.0104 0.0031 0.0022
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0547 0.0311 0.4248
Plasmodium vivax hypothetical protein 0.0239 0.0116 0.218
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0772 0.0453 0.6186
Schistosoma mansoni cation-transporting atpase fly 0.009 0.0022 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0688 0.04 0.5364
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0104 0.0031 0.0339
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0239 0.0116 0.218
Echinococcus granulosus phospholipid transporting atpase ih 0.0091 0.0023 0.0014
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0358 0.0192 0.2591
Brugia malayi G-protein coupled receptor 0.0104 0.0031 0.0416
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0091 0.0023 0.0012
Echinococcus multilocularis somatostatin receptor 0.0104 0.0031 0.0022
Loa Loa (eye worm) hypothetical protein 0.0241 0.0118 0.1608
Echinococcus granulosus neuropeptide s receptor 0.0104 0.0031 0.0022
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0358 0.0192 0.259
Loa Loa (eye worm) calcium ATPase 0.0434 0.024 0.3276
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Brugia malayi Serotonin receptor 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.0358 0.0192 0.262
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0239 0.0116 0.1597
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0478 0.0267 0.3484
Schistosoma mansoni cation-transporting atpase worm 0.0241 0.0118 0.1523
Echinococcus multilocularis aldo keto reductase 0.0358 0.0192 0.0183
Schistosoma mansoni fkbp-rapamycin associated protein 0.0669 0.0388 0.5204
Mycobacterium ulcerans hypothetical protein 0.0104 0.0031 0.0662
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0647 0.0374 0.4996
Trichomonas vaginalis PIKK family atypical protein kinase 0.07 0.0407 0.5472
Loa Loa (eye worm) hypothetical protein 0.0187 0.0083 0.1137
Trichomonas vaginalis PIKK family atypical protein kinase 0.1193 0.0719 0.9893
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0104 0.0031 0.0022
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0242 0.0118 0.1369
Leishmania major hypothetical protein, conserved 0.5786 0.362 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Echinococcus multilocularis dro:myosuppressin receptor 0.0104 0.0031 0.0022
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0688 0.04 0.5364
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0647 0.0374 0.5054
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0239 0.0116 0.218
Brugia malayi calcium ATPase 0.0338 0.0179 0.2417
Plasmodium vivax cation transporting ATPase, putative 0.0241 0.0118 0.2218
Schistosoma mansoni growth hormone secretagogue receptor 0.0104 0.0031 0.0339
Onchocerca volvulus 0.0104 0.0031 0.0123
Loa Loa (eye worm) G-protein coupled receptor 0.0104 0.0031 0.042
Loa Loa (eye worm) hypothetical protein 0.0505 0.0284 0.3887
Entamoeba histolytica phospholipid-transporting ATPase IA, putative 0.0091 0.0023 0.0012
Echinococcus granulosus nervana 2 0.1213 0.0731 0.0723
Brugia malayi neuropeptide F receptor 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.0669 0.0388 0.5303
Loa Loa (eye worm) hypothetical protein 0.0239 0.0116 0.1586
Echinococcus multilocularis Zinc finger, PHD finger 0.0292 0.015 0.0141
Schistosoma mansoni opsin-like receptor 0.0104 0.0031 0.0339
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0771 0.0452 0.0443
Echinococcus multilocularis nervana 2 0.1213 0.0731 0.0723
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0151 0.0061 0.0176
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0669 0.0388 0.5242
Onchocerca volvulus 0.0104 0.0031 0.0123
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0826 0.0487 0.0478
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0241 0.0118 0.1357
Trypanosoma cruzi P-type H+-ATPase, putative 0.0338 0.0179 0.0515
Echinococcus granulosus calcium transporting atpase 0.0621 0.0357 0.0349
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.1213 0.0731 1
Brugia malayi E1-E2 ATPase family protein 0.0491 0.0275 0.3721
Echinococcus multilocularis neuropeptides capa receptor 0.0104 0.0031 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.1174 0.0707 0.9722
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0241 0.0118 0.1357
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0241 0.0118 0.1357
Schistosoma mansoni aldo-keto reductase 0.0358 0.0192 0.2531
Leishmania major aminophospholipid translocase, putative 0.0091 0.0023 0.0063
Echinococcus multilocularis orexin receptor type 2 0.0104 0.0031 0.0022
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1226 0.074 0.2133
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0091 0.0023 0.0066
Echinococcus multilocularis fmrfamide receptor 0.0104 0.0031 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Giardia lamblia Aldose reductase 0.0358 0.0192 0.2408
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Onchocerca volvulus 0.0239 0.0116 0.1325
Schistosoma mansoni adenoreceptor 0.0104 0.0031 0.0339
Loa Loa (eye worm) hypothetical protein 0.0069 0.0009 0.0126
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0647 0.0374 0.4996
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0771 0.0452 0.1304
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0339 0.018 0.2238
Schistosoma mansoni amine GPCR 0.0104 0.0031 0.0339
Trichomonas vaginalis cation-transporting ATPase, putative 0.0771 0.0452 0.6107
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0684 0.0397 0.5471
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Onchocerca volvulus 0.0358 0.0192 0.2391
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0621 0.0357 0.4921
Loa Loa (eye worm) hypothetical protein 0.0744 0.0435 0.5947
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0338 0.0179 0.0515
Plasmodium falciparum phospholipid-transporting ATPase, putative 0.0091 0.0023 0.0019
Loa Loa (eye worm) hypothetical protein 0.1213 0.0731 1
Echinococcus multilocularis phosphoserine phosphatase 0.0151 0.0061 0.0052
Echinococcus granulosus alpha 1A adrenergic receptor 0.0104 0.0031 0.0022
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1174 0.0707 0.973
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0826 0.0487 0.0478
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Entamoeba histolytica alcohol dehydrogenase, putative 0.0104 0.0031 0.0126
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0621 0.0357 0.479
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0765 0.0449 0.6055
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0091 0.0023 0.0063
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.0031 0.0339
Leishmania major P-type H -ATPase, putative 0.0489 0.0274 0.0758
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0239 0.0116 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.1193 0.0719 0.9893
Echinococcus granulosus serotonin receptor 0.0104 0.0031 0.0022
Echinococcus multilocularis sex peptide receptor 0.0104 0.0031 0.0022
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.1213 0.0731 0.0723
Echinococcus granulosus neuropeptide FF receptor 2 0.0104 0.0031 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0239 0.0116 0.0334
Trypanosoma cruzi copper-transporting ATPase, putative 0.0151 0.0061 0.0176
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1196 0.072 0.199
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0771 0.0452 0.6225
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0744 0.0435 0.5926
Trypanosoma cruzi target of rapamycin kinase 3 0.1196 0.072 0.2077
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0104 0.0031 0.0022
Echinococcus granulosus tachykinin peptides receptor 99D 0.0104 0.0031 0.0022
Schistosoma mansoni opsin-like receptor 0.0104 0.0031 0.0339
Giardia lamblia Copper-transporting P-type ATPase 0.0241 0.0118 0.1357
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0358 0.0192 0.2408
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0546 0.031 1
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0338 0.0179 0.2417
Trichomonas vaginalis PIKK family atypical protein kinase 0.1195 0.072 0.9914
Onchocerca volvulus 0.0104 0.0031 0.0123
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.012 0.0041 0.0118
Trichomonas vaginalis cation-transporting ATPase, putative 0.0771 0.0452 0.6107
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0091 0.0023 0.0314
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0771 0.0452 0.6107
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0241 0.0118 0.1357
Loa Loa (eye worm) hypothetical protein 0.0241 0.0118 0.1608
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0104 0.0031 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.1195 0.072 0.9914
Echinococcus granulosus neuropeptides capa receptor 0.0104 0.0031 0.0022
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0239 0.0116 0.15
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Trichomonas vaginalis PIKK family atypical protein kinase 0.043 0.0237 0.3055
Echinococcus multilocularis aldo keto reductase 0.0358 0.0192 0.0183
Trichomonas vaginalis cation-transporting ATPase, putative 0.0091 0.0023 0.0012
Onchocerca volvulus 0.0104 0.0031 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0338 0.0179 0.2445
Trypanosoma cruzi hypothetical protein, conserved 0.5548 0.3469 1
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0091 0.0023 0.0014
Brugia malayi putative neuropeptide receptor 0.0104 0.0031 0.0416
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0104 0.0031 0.0123
Plasmodium vivax copper-transporting ATPase, putative 0.0241 0.0118 0.2218
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0292 0.015 0.1959
Trichomonas vaginalis aldo-keto reductase, putative 0.0104 0.0031 0.0126
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0239 0.0116 0.1568
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0091 0.0023 0.0012
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0153 0.0062 0.0571
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0091 0.0023 0.0012
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1205 0.0726 1
Entamoeba histolytica protein kinase rad3, putative 0.0669 0.0388 0.5193
Trichomonas vaginalis PIKK family atypical protein kinase 0.1193 0.0719 0.9893
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0179 0.0079 0.1063
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.1184 0.0713 0.9807
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Echinococcus granulosus serine protein kinase ATM 0.0684 0.0397 0.0389
Schistosoma mansoni pol-related 0.0358 0.0192 0.2531
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0669 0.0388 0.1118
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0771 0.0452 0.6107
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0771 0.0452 0.6107
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Plasmodium falciparum calcium-transporting ATPase 0.0621 0.0357 0.7782
Leishmania major phosphatidylinositol 3-kinase, putative 0.1174 0.0707 0.1953
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1205 0.0726 0.0718
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0104 0.0031 0.0022
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0241 0.0118 0.0109
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1205 0.0726 1
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0104 0.0031 0.0206
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0408 0.0223 0.2857
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0104 0.0031 0.0339
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0644 0.0372 0.4967
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0241 0.0118 0.2852
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0358 0.0192 0.2409
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0239 0.0116 0.1334
Leishmania major calcium-transporting ATPase, putative 0.0621 0.0357 0.0987
Schistosoma mansoni potassium channel beta 0.0104 0.0031 0.0341
Onchocerca volvulus 0.0104 0.0031 0.0123
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.1213 0.0731 0.0723
Schistosoma mansoni opsin-like receptor 0.0104 0.0031 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.1184 0.0713 0.9807
Trichomonas vaginalis conserved hypothetical protein 0.0505 0.0284 0.3724
Loa Loa (eye worm) hypothetical protein 0.0771 0.0452 0.6183
Onchocerca volvulus 0.0104 0.0031 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.043 0.0237 0.3055
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0771 0.0452 0.6174
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0826 0.0487 0.6558
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0358 0.0192 0.2531
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0358 0.0192 0.259
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0104 0.0031 0.0022
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0104 0.0031 0.0339
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0771 0.0452 0.1304
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Echinococcus granulosus dro:myosuppressin receptor 0.0104 0.0031 0.0022
Echinococcus granulosus orexin receptor type 2 0.0104 0.0031 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0669 0.0388 0.5193
Echinococcus granulosus g protein coupled receptor 0.0104 0.0031 0.0022
Echinococcus multilocularis copper transporting ATPase 1 0.0241 0.0118 0.0109
Loa Loa (eye worm) G-protein coupled receptor 0.0104 0.0031 0.042
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Mycobacterium tuberculosis Conserved hypothetical protein 0.0239 0.0116 0.2798
Leishmania major phosphatidylinositol kinase related protein, putative 0.0254 0.0126 0.0347
Schistosoma mansoni hypothetical protein 0.0104 0.0031 0.0339
Echinococcus multilocularis cation transporting atpase worm 0.0241 0.0118 0.0109
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0771 0.0452 0.0443
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0292 0.015 0.1812
Schistosoma mansoni biogenic amine (5HT) receptor 0.0809 0.0476 0.6408
Schistosoma mansoni cation-transporting atpase worm 0.009 0.0022 0.022
Schistosoma mansoni copper ABC transporter ATPase 0.0241 0.0118 0.1523
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0091 0.0023 0.0312
Onchocerca volvulus 0.0104 0.0031 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Toxoplasma gondii aldose reductase, putative 0.0358 0.0192 0.2434
Echinococcus multilocularis g-protein coupled receptor 0.0104 0.0031 0.0022
Entamoeba histolytica aldose reductase, putative 0.0358 0.0192 0.2408
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Echinococcus multilocularis neuropeptide s receptor 0.0104 0.0031 0.0022
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0104 0.0031 0.0085
Onchocerca volvulus 0.0358 0.0192 0.2391
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0239 0.0116 0.0334
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0621 0.0357 0.103
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0091 0.0023 0.0012
Loa Loa (eye worm) oxidoreductase 0.0358 0.0192 0.262
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0373 0.0201 0.0578
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0585 0.0335 1
Echinococcus granulosus cation transporting ATPase 13A3 0.0241 0.0118 0.0109
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0104 0.0031 0.0339
Brugia malayi neuropeptide F receptor 0.0104 0.0031 0.0416
Echinococcus granulosus g protein coupled receptor 0.0104 0.0031 0.0022
Trypanosoma brucei P-type H+-ATPase, putative 0.0489 0.0274 0.3778
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0104 0.0031 0.0339
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0091 0.0023 0.0012
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0241 0.0118 0.1357
Onchocerca volvulus 0.0104 0.0031 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.1193 0.0719 0.9893
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Schistosoma mansoni atpase class VI type 11c 0.0153 0.0062 0.0762
Onchocerca volvulus 0.1213 0.0731 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0104 0.0031 0.0416
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Brugia malayi Membrane calcium atpase protein 3 0.0621 0.0357 0.4831
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.063 0.0363 0.7779
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0239 0.0116 0.15
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0684 0.0397 0.5335
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0239 0.0116 0.0334
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0753 0.0441 0.6071
Brugia malayi calcium ATPase 0.0283 0.0144 0.1946
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0239 0.0116 0.0107
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0104 0.0031 0.0022
Schistosoma mansoni transmemberane protein 0.1213 0.0731 0.9885
Trichomonas vaginalis PIKK family atypical protein kinase 0.068 0.0395 0.5293
Echinococcus granulosus cation transporting ATPase 13A1 0.0241 0.0118 0.0109
Brugia malayi Potential phospholipid-transporting ATPase IA 0.009 0.0022 0.0298
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0091 0.0023 0.0012
Echinococcus granulosus nervana 2 0.1213 0.0731 0.0723
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0621 0.0357 0.0349
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.1213 0.0731 0.0723
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0523 0.0295 0.633
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0104 0.0031 0.0416
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.1186 0.0714 0.9829
Echinococcus granulosus aldo keto reductase 0.0358 0.0192 0.0183
Echinococcus multilocularis serotonin receptor 0.0809 0.0476 0.0467
Brugia malayi Cytochrome P450 family protein 0.0116 0.0039 0.052
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.063 0.0363 0.7779
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0151 0.0061 0.0559
Echinococcus granulosus voltage gated potassium channel subunit 0.0104 0.0031 0.0022
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0772 0.0453 0.6119
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1185 0.0714 0.1972
Echinococcus granulosus copper transporting ATPase 1 0.0241 0.0118 0.0109
Onchocerca volvulus 0.0104 0.0031 0.0123
Echinococcus multilocularis neuropeptide receptor 0.0104 0.0031 0.0022
Echinococcus granulosus tm gpcr rhodopsin 0.0104 0.0031 0.0022
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.1213 0.0731 0.9885
Echinococcus multilocularis phosphoserine phosphatase 0.0151 0.0061 0.0052
Brugia malayi follicle stimulating hormone receptor 0.0104 0.0031 0.0416
Trichomonas vaginalis cation-transporting ATPase, putative 0.0771 0.0452 0.6107
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0647 0.0374 0.4996
Trypanosoma cruzi P-type H+-ATPase, putative 0.0489 0.0274 0.0791
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1205 0.0726 0.2094
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trichomonas vaginalis cation-transporting ATPase, putative 0.0489 0.0274 0.3583
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0771 0.0452 0.6107
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1205 0.0726 1
Brugia malayi putative neuropeptide receptor NPR1 0.0104 0.0031 0.0416
Leishmania major phosphatidylinositol 3-kinase, putative 0.0292 0.015 0.0413
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Loa Loa (eye worm) hypothetical protein 0.0795 0.0468 0.6392
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0358 0.0192 0.0529
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0292 0.015 0.0141
Echinococcus granulosus Na:K ATPase alpha subunit 0.0644 0.0372 0.0363
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0239 0.0116 0.0107
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0373 0.0201 0.2712
Echinococcus granulosus g protein coupled receptor 0.0104 0.0031 0.0022
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0241 0.0118 0.159
Trichomonas vaginalis PIKK family atypical protein kinase 0.1174 0.0707 0.9722
Schistosoma mansoni neuropeptide F-like receptor 0.0104 0.0031 0.0339
Plasmodium vivax P-type ATPase4, putative 0.0772 0.0453 1
Brugia malayi Dopamine receptor protein 1 0.0104 0.0031 0.0416
Trypanosoma cruzi aldo-keto reductase 0.0358 0.0192 0.0552
Echinococcus granulosus nervana 2 0.1213 0.0731 0.0723
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0434 0.024 0.3088
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0358 0.0192 0.2409
Echinococcus multilocularis calcium transporting atpase 0.0621 0.0357 0.0349
Plasmodium vivax aldehyde reductase, putative 0.0104 0.0031 0.0206
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1226 0.074 1
Onchocerca volvulus 0.0104 0.0031 0.0123
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0292 0.015 0.2961
Trichomonas vaginalis PIKK family atypical protein kinase 0.1184 0.0713 0.9807
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0104 0.0031 0.0127
Echinococcus granulosus phospholipid transporting ATPase IF 0.0091 0.0023 0.0014
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1196 0.072 0.9917
Trichomonas vaginalis PIKK family atypical protein kinase 0.1174 0.0707 0.9722
Trichomonas vaginalis cation-transporting ATPase, putative 0.0091 0.0023 0.0012
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0091 0.0023 0.0012
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0647 0.0374 0.4996
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0091 0.0023 0.0012
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Loa Loa (eye worm) melatonin receptor type 1A 0.0104 0.0031 0.042
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0282 0.0143 0.0413
Trichomonas vaginalis aldo/keto reductase, putative 0.0358 0.0192 0.2408
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Loa Loa (eye worm) phosphatidylinositol 3 0.0239 0.0116 0.1586
Loa Loa (eye worm) hypothetical protein 0.0446 0.0247 0.3374
Trypanosoma brucei calcium-transporting ATPase, putative 0.0373 0.0201 0.2762
Schistosoma mansoni myosin xvIII 0.0104 0.0031 0.0339
Echinococcus granulosus somatostatin receptor 0.0104 0.0031 0.0022
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.068 0.0395 0.5293
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0091 0.0023 0.0312
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0771 0.0452 0.6225
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0545 0.031 0.4081
Mycobacterium ulcerans oxidoreductase 0.0358 0.0192 0.4106
Echinococcus multilocularis aldehyde reductase 0.0255 0.0126 0.0117
Echinococcus multilocularis phosphoserine phosphatase 0.0151 0.0061 0.0052
Giardia lamblia Phosphatidylinositol 4-kinase 0.0239 0.0116 0.1334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.1186 0.0714 0.9829
Toxoplasma gondii P-type ATPase PMA1 0.0489 0.0274 0.3622
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0241 0.0118 0.2521
Toxoplasma gondii target of rapamycin (TOR), putative 0.1193 0.0719 1
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0104 0.0031 0.0126
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0104 0.0031 0.042
Trypanosoma brucei aldo-keto reductase, putative 0.0358 0.0192 0.2638
Trichomonas vaginalis aldo-keto reductase, putative 0.0104 0.0031 0.0126
Mycobacterium leprae Conserved hypothetical protein 0.0255 0.0126 0.3412
Trichomonas vaginalis PIKK family atypical protein kinase 0.1184 0.0713 0.9807
Schistosoma mansoni neuropeptide receptor 0.0104 0.0031 0.0339
Trichomonas vaginalis aldo/keto reductase, putative 0.0358 0.0192 0.2408
Loa Loa (eye worm) oxidoreductase 0.0358 0.0192 0.262
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0292 0.015 0.2046
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0358 0.0192 0.2409
Brugia malayi Dopamine receptor 0.0104 0.0031 0.0416
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0239 0.0116 0.218
Echinococcus granulosus hypothetical protein 0.0358 0.0192 0.0183
Brugia malayi FAT domain containing protein 0.0505 0.0284 0.3843
Loa Loa (eye worm) phosphatidylinositol 3 0.1185 0.0714 0.976
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0772 0.0453 0.0444
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0373 0.0201 0.2743
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0239 0.0116 0.1349
Echinococcus multilocularis neuropeptides capa receptor 0.0104 0.0031 0.0022
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0771 0.0452 0.1249
Echinococcus granulosus allatostatin A receptor 0.0104 0.0031 0.0022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.0031 0.0339
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1185 0.0714 0.9827
Schistosoma mansoni sodium / potassium ATPase beta chain 0.1213 0.0731 0.9885
Loa Loa (eye worm) phosphatidylinositol 3 0.1205 0.0726 0.9932
Onchocerca volvulus 0.0794 0.0467 0.6269
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0104 0.0031 0.0422
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0621 0.0357 0.479
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.1213 0.0731 0.0723
Trichomonas vaginalis PIKK family atypical protein kinase 0.0688 0.04 0.5364
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0292 0.015 0.0431
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0241 0.0118 0.2521
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0771 0.0452 0.1304
Trichomonas vaginalis PIKK family atypical protein kinase 0.0239 0.0116 0.1334
Echinococcus multilocularis phosphoserine phosphatase 0.0151 0.0061 0.0052
Entamoeba histolytica hypothetical protein 0.0239 0.0116 0.1334
Echinococcus multilocularis nervana 2 0.1213 0.0731 0.0723
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0104 0.0031 0.042
Trichomonas vaginalis conserved hypothetical protein 0.0744 0.0435 0.5862
Loa Loa (eye worm) hypothetical protein 0.0304 0.0158 0.2155
Trypanosoma brucei P-type H+-ATPase, putative 0.0489 0.0274 0.3778
Echinococcus granulosus sex peptide receptor 0.0104 0.0031 0.0022
Brugia malayi hypothetical protein 0.0153 0.0062 0.0835
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0104 0.0031 0.0416
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0091 0.0023 0.0012
Toxoplasma gondii FATC domain-containing protein 0.0684 0.0397 0.5388
Echinococcus granulosus biogenic amine 5HT receptor 0.0104 0.0031 0.0022
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0772 0.0453 1
Giardia lamblia Aldose reductase 0.0358 0.0192 0.2408
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0104 0.0031 0.0022
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0669 0.0388 0.0379
Entamoeba histolytica aldose reductase, putative 0.0358 0.0192 0.2408
Brugia malayi Tachykinin-like peptides receptor 99D 0.0104 0.0031 0.0416
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0104 0.0031 0.0022
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0239 0.0116 0.218
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0241 0.0118 0.1523
Schistosoma mansoni biogenic amine (5HT) receptor 0.0104 0.0031 0.0339
Brugia malayi Serotonin receptor 0.0104 0.0031 0.0416
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1226 0.074 0.0731
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0239 0.0116 0.1568
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0669 0.0388 0.0379
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Loa Loa (eye worm) neuropeptide F receptor 0.0104 0.0031 0.042
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0241 0.0118 0.0339
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0292 0.015 0.0141
Trypanosoma cruzi aldo/keto reductase, putative 0.0358 0.0192 0.0552
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0358 0.0192 0.2408
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0241 0.0118 0.2521
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0104 0.0031 0.0022
Schistosoma mansoni hypothetical protein 0.0505 0.0284 0.3794
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0338 0.0179 0.0515
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0621 0.0357 0.4762
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0523 0.0295 0.8697
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0239 0.0116 0.15
Echinococcus multilocularis G-protein coupled receptor, putative 0.0104 0.0031 0.0022
Echinococcus granulosus tm gpcr rhodopsin 0.0104 0.0031 0.0022
Brugia malayi sulfakinin receptor protein 0.0104 0.0031 0.0416
Brugia malayi ORL1-like opioid receptor 0.0104 0.0031 0.0416
Chlamydia trachomatis metal transport ATPase 0.0241 0.0118 0.5
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0795 0.0468 0.629
Echinococcus multilocularis nervana 2 0.1213 0.0731 0.0723
Onchocerca volvulus 0.0104 0.0031 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.1193 0.0719 0.9893
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0771 0.0452 0.1249
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0292 0.015 0.1832
Leishmania major prostaglandin f synthase, putative 0.0358 0.0192 0.0529
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0104 0.0031 0.0022
Echinococcus granulosus neuropeptide receptor 0.0104 0.0031 0.0022
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0241 0.0118 0.1357
Entamoeba histolytica hypothetical protein 0.0239 0.0116 0.1334
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1205 0.0726 1
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Onchocerca volvulus 0.0358 0.0192 0.2391
Schistosoma mansoni ATPase 0.0771 0.0452 0.6081
Echinococcus granulosus neuropeptides capa receptor 0.0104 0.0031 0.0022
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0241 0.0118 0.2852
Plasmodium vivax hypothetical protein, conserved 0.0239 0.0116 0.218
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Echinococcus multilocularis G protein coupled receptor 139 0.0104 0.0031 0.0022
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0151 0.0061 0.0559
Trichomonas vaginalis PIKK family atypical protein kinase 0.1184 0.0713 0.9807
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0358 0.0192 0.2639
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0795 0.0468 0.6392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0239 0.0116 0.1334
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0433 0.0239 0.3077
Loa Loa (eye worm) oxidoreductase 0.0358 0.0192 0.262
Leishmania major proton motive ATPase, putative 0.0241 0.0118 0.0325
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0239 0.0116 0.218
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trichomonas vaginalis PIKK family atypical protein kinase 0.1205 0.0726 1
Schistosoma mansoni hypothetical protein 0.0104 0.0031 0.0339
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1205 0.0726 0.9817
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0358 0.0192 0.259
Trichomonas vaginalis aldo-keto reductase, putative 0.0104 0.0031 0.0126
Onchocerca volvulus Neuropeptide F receptor homolog 0.0104 0.0031 0.0123
Entamoeba histolytica phospholipid-transporting ATPase Neo1, putative 0.0091 0.0023 0.0012
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0104 0.0031 0.0022
Mycobacterium leprae conserved hypothetical protein 0.0239 0.0116 0.305
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0771 0.0452 0.6107
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1205 0.0726 0.2007
Schistosoma mansoni neuropeptide f receptor 76f 0.0104 0.0031 0.0339
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.1213 0.0731 0.9885
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0241 0.0118 0.159
Echinococcus granulosus neuropeptide receptor A26 0.0104 0.0031 0.0022
Toxoplasma gondii cation-transporting atpase family protein 0.0151 0.0061 0.0559
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Loa Loa (eye worm) glutamate receptor 0.0056 0.0001 0.0014
Schistosoma mansoni alpha-1 adrenergic receptor 0.0104 0.0031 0.0339
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0621 0.0357 0.0349
Echinococcus multilocularis neuropeptide receptor A26 0.0104 0.0031 0.0022
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Onchocerca volvulus 0.0358 0.0192 0.2391
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0505 0.0284 0.0275
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0338 0.0179 0.225
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0292 0.015 0.0141
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0104 0.0031 0.0022
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0104 0.0031 0.0416
Echinococcus granulosus aldo keto reductase 0.0358 0.0192 0.0183
Loa Loa (eye worm) hypothetical protein 0.0264 0.0132 0.1806
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0239 0.0116 0.1349
Echinococcus multilocularis phosphoserine phosphatase 0.0151 0.0061 0.0052
Onchocerca volvulus 0.0358 0.0192 0.2391
Giardia lamblia Hypothetical protein 0.0239 0.0116 0.1334
Loa Loa (eye worm) phosphatidylinositol 3 0.0239 0.0116 0.1586
Schistosoma mansoni hypothetical protein 0.0239 0.0116 0.15
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Leishmania major phosphatidylinositol 4-kinase, putative 0.0239 0.0116 0.032
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.1213 0.0731 0.0723
Echinococcus granulosus phospholipid transporting ATPase IA 0.0091 0.0023 0.0014
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0091 0.0023 0.0309
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0091 0.0023 0.0012
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0545 0.031 0.4081
Trypanosoma cruzi proton motive ATPase 1, putative 0.0151 0.0061 0.0176
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0091 0.0023 0.0066
Schistosoma mansoni type V p-type atpase isoform 0.0241 0.0118 0.1523
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0358 0.0192 0.2409
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Trypanosoma brucei prostaglandin f synthase 0.0358 0.0192 0.2638
Plasmodium vivax phospholipid-transporting ATPase, putative 0.0091 0.0023 0.0019
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0644 0.0372 0.4987
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0644 0.0372 0.0363
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.1213 0.0731 0.0723
Echinococcus multilocularis neuropeptide FF receptor 2 0.0104 0.0031 0.0022
Plasmodium falciparum aldo-keto reductase, putative 0.0104 0.0031 0.0206
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Plasmodium vivax calcium-transporting ATPase, putative 0.0772 0.0453 1
Schistosoma mansoni amine GPCR 0.0104 0.0031 0.0339
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Entamoeba histolytica hypothetical protein 0.0684 0.0397 0.533
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Onchocerca volvulus 0.0104 0.0031 0.0123
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.046 0.0256 0.0247
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0091 0.0023 0.0014
Onchocerca volvulus 0.0358 0.0192 0.2391
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0241 0.0118 0.2521
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0104 0.0031 0.042
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Schistosoma mansoni ATPase 0.0771 0.0452 0.6081
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0292 0.015 0.1812
Echinococcus granulosus hypothetical protein 0.0104 0.0031 0.0022
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0358 0.0192 0.2409
Leishmania major copper-transporting ATPase-like protein, putative 0.0241 0.0118 0.0325
Loa Loa (eye worm) oxidoreductase 0.0358 0.0192 0.262
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.062 0.0357 0.475
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.5887 1 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0446 0.0247 0.0711
Loa Loa (eye worm) phosphatidylinositol 3 0.012 0.0041 0.0561
Schistosoma mansoni neuropeptide F-like receptor 0.0104 0.0031 0.0339
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Schistosoma mansoni biogenic amine receptor 0.0104 0.0031 0.0339
Giardia lamblia GTOR 0.1205 0.0726 1
Entamoeba histolytica hypothetical protein 0.0239 0.0116 0.1334
Onchocerca volvulus 0.0104 0.0031 0.0123
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0091 0.0023 0.0066
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.1213 0.0731 0.9885
Echinococcus multilocularis cation transporting ATPase 13A3 0.0241 0.0118 0.0109
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0292 0.015 0.1812
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0771 0.0452 0.6107
Schistosoma mansoni cation-transporting ATPase 0.0241 0.0118 0.1523
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1226 0.074 0.2133
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Echinococcus multilocularis fmrfamide receptor 0.0104 0.0031 0.0022
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0241 0.0118 0.3109
Trichomonas vaginalis cation-transporting ATPase, putative 0.0241 0.0118 0.1357
Echinococcus granulosus aldo keto reductase 0.0358 0.0192 0.0183
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0239 0.0116 0.0107
Schistosoma mansoni phospholipid-transporting atpase 1 (aminophospholipid flippase 1) 0.009 0.0022 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.069 0.0401 0.5386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0248 0.0122 0.1419
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0621 0.0357 0.0349
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0104 0.0031 0.0339
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0104 0.0031 0.0022
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0547 0.0311 0.42
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0434 0.024 0.3238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0684 0.0397 0.533
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0104 0.0031 0.0022
Schistosoma mansoni cation-transporting atpase worm 0.0241 0.0118 0.1523
Loa Loa (eye worm) phosphatidylinositol kinase 0.0239 0.0116 0.1586
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0358 0.0192 0.0553
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0647 0.0374 0.1078
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0241 0.0118 0.1372
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1226 0.074 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.1195 0.072 0.9914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0358 0.0192 0.2408
Brugia malayi AKH receptor 0.0104 0.0031 0.0416
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0771 0.0452 0.6107
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0239 0.0116 0.1568
Echinococcus granulosus G protein coupled receptor 139 0.0104 0.0031 0.0022
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0292 0.015 0.0431
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0239 0.0116 0.1334
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0104 0.0031 0.0339
Loa Loa (eye worm) neuropeptide F receptor 0.0104 0.0031 0.042
Giardia lamblia Phospholipid-transporting ATPase IIB, putative 0.0091 0.0023 0.0012
Loa Loa (eye worm) phosphatidylinositol 3 0.076 0.0445 0.6087
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0241 0.0118 0.2521
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0153 0.0062 0.0053
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.1213 0.0731 0.0723
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0771 0.0452 0.6107
Echinococcus multilocularis aldo keto reductase 0.0358 0.0192 0.0183
Echinococcus multilocularis aldo keto reductase 0.0358 0.0192 0.0183
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.1195 0.072 0.9914
Trichomonas vaginalis PIKK family atypical protein kinase 0.1174 0.0707 0.9722
Trichomonas vaginalis PIKK family atypical protein kinase 0.1205 0.0726 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1205 0.0726 0.9819
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0358 0.0192 0.0183
Leishmania major calcium motive p-type ATPase, putative 0.0621 0.0357 0.0987
Echinococcus granulosus fmrfamide receptor 0.0104 0.0031 0.0022
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0505 0.0284 0.0275
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0091 0.0023 0.0014
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0241 0.0118 0.1372
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0258 0.0128 0.1763
Treponema pallidum cation-transporting ATPase, P-type 0.0241 0.0118 1
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.1213 0.0731 0.0723
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0104 0.0031 0.0418
Onchocerca volvulus 0.0104 0.0031 0.0125
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0772 0.0453 0.0444
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0394 0.0214 0.2727
Onchocerca volvulus 0.0104 0.0031 0.0123
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0358 0.0192 0.0183
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0239 0.0116 0.0107
Onchocerca volvulus 0.0104 0.0031 0.0123
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Leishmania major P-type H -ATPase, putative 0.0489 0.0274 0.0758
Trypanosoma brucei phospholipid-transporting ATPase, putative 0.009 0.0022 0.0303
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0358 0.0192 0.0529
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0239 0.0116 0.1334
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0091 0.0023 0.0063
Loa Loa (eye worm) E1-E2 ATPase 0.0489 0.0274 0.3752
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0292 0.015 0.1832
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0091 0.0023 0.0012
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0241 0.0118 0.0339
Brugia malayi GnHR receptor homolog 0.0104 0.0031 0.0416
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.1185 0.0714 0.9822
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0031 0.0022
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0684 0.0397 0.1146
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.0031 0.0339
Onchocerca volvulus 0.0239 0.0116 0.1325
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0104 0.0031 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0031 0.0339
Echinococcus granulosus neuropeptide Y receptor 0.0104 0.0031 0.0022
Echinococcus multilocularis neuropeptide Y receptor 0.0104 0.0031 0.0022
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Toxoplasma gondii P-type ATPase4, putative 0.0772 0.0453 0.6186
Echinococcus granulosus cation transporting atpase worm 0.0241 0.0118 0.0109
Schistosoma mansoni neuropeptide receptor 0.0104 0.0031 0.0339
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0772 0.0453 0.9707
Echinococcus granulosus g-protein coupled receptor 0.0104 0.0031 0.0022
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.046 0.0256 0.3502
Echinococcus granulosus 7tm_1 domain containing protein 0.0104 0.0031 0.0022
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0292 0.015 0.2961
Schistosoma mansoni neuropeptide receptor 0.0104 0.0031 0.0339
Echinococcus multilocularis nervana 2 0.1213 0.0731 0.0723
Echinococcus multilocularis phosphoserine phosphatase 0.0151 0.0061 0.0052
Echinococcus granulosus nervana 2 0.1213 0.0731 0.0723
Brugia malayi hypothetical protein 0.0104 0.0031 0.0416
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0621 0.0357 0.103
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0151 0.0061 0.0176
Trichomonas vaginalis aldo-keto reductase, putative 0.0358 0.0192 0.2408
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0358 0.0192 0.259
Leishmania major hypothetical protein, unknown function 0.0239 0.0116 0.032
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0104 0.0031 0.0416
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0292 0.015 0.1812
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trypanosoma brucei calcium-transporting ATPase, putative 0.0091 0.0023 0.0314
Loa Loa (eye worm) phosphatidylinositol 3 0.0239 0.0116 0.1586
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0621 0.0357 0.479
Leishmania major phosphatidylinositol kinase, putative 0.0239 0.0116 0.032
Echinococcus granulosus phospholipid transporting ATPase VA 0.0153 0.0062 0.0053
Echinococcus granulosus biogenic amine 5HT receptor 0.0809 0.0476 0.0467
Trypanosoma cruzi aldo/keto reductase, putative 0.0104 0.0031 0.0089
Echinococcus granulosus aldehyde reductase 0.0255 0.0126 0.0117
Brugia malayi G protein-coupled receptor 0.0104 0.0031 0.0416
Schistosoma mansoni hypothetical protein 0.0104 0.0031 0.0339
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0305 0.0158 0.1931
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0091 0.0023 0.0314
Echinococcus granulosus neuropeptide Y receptor 0.0104 0.0031 0.0022
Echinococcus multilocularis 0.0239 0.0116 0.0107
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0621 0.0357 0.4813
Schistosoma mansoni biogenic amine receptor 0.0104 0.0031 0.0339
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0647 0.0374 0.1078
Brugia malayi G-protein coupled receptor 0.0104 0.0031 0.0416
Loa Loa (eye worm) hypothetical protein 0.0104 0.0031 0.042
Schistosoma mansoni aldo-keto reductase 0.0358 0.0192 0.2531
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0292 0.015 0.2023
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0104 0.0031 0.0022
Trypanosoma cruzi P-type H+-ATPase, putative 0.0489 0.0274 0.0791
Brugia malayi Metabotropic glutamate receptor precursor. 0.0056 0.0001 0.0014
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0292 0.015 0.1959

Activities

Activity type Activity value Assay description Source Reference
RBA (binding) = 90 Relative binding affinity against estrogen receptor of rat uterine tissue was determined relative to estradiol ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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