Detailed information for compound 340477

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 364.351 | Formula: C20H16N2O5
  • H donors: 2 H acceptors: 4 LogP: 1.85 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cc(=O)c2c(o1)cccc2)N[C@H](C(=O)C(=O)N)Cc1ccccc1
  • InChi: 1S/C20H16N2O5/c21-19(25)18(24)14(10-12-6-2-1-3-7-12)22-20(26)17-11-15(23)13-8-4-5-9-16(13)27-17/h1-9,11,14H,10H2,(H2,21,25)(H,22,26)/t14-/m0/s1
  • InChiKey: MBYZTIZOYMTNOR-AWEZNQCLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens calpain 1, (mu/I) large subunit Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127139 All targets in OG5_127139
Brugia malayi calpain family protein 1 Get druggable targets OG5_127139 All targets in OG5_127139
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) Get druggable targets OG5_127139 All targets in OG5_127139
Loa Loa (eye worm) calpain family protein 1 Get druggable targets OG5_127139 All targets in OG5_127139
Schistosoma mansoni family C2 unassigned peptidase (C02 family) Get druggable targets OG5_127139 All targets in OG5_127139
Echinococcus granulosus family C2 unassigned peptidase C02 family Get druggable targets OG5_127139 All targets in OG5_127139
Echinococcus granulosus calpain A Get druggable targets OG5_127139 All targets in OG5_127139
Onchocerca volvulus Get druggable targets OG5_127139 All targets in OG5_127139
Brugia malayi calpain family protein 1 Get druggable targets OG5_127139 All targets in OG5_127139
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127139 All targets in OG5_127139
Loa Loa (eye worm) calpain family protein 1 Get druggable targets OG5_127139 All targets in OG5_127139
Schistosoma mansoni family C2 unassigned peptidase (C02 family) Get druggable targets OG5_127139 All targets in OG5_127139
Echinococcus multilocularis calpain A Get druggable targets OG5_127139 All targets in OG5_127139
Echinococcus multilocularis calpain family protein 1, d Get druggable targets OG5_127139 All targets in OG5_127139
Schistosoma japonicum Calpain-A, putative Get druggable targets OG5_127139 All targets in OG5_127139
Schistosoma mansoni family C2 unassigned peptidase (C02 family) Get druggable targets OG5_127139 All targets in OG5_127139
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127139 All targets in OG5_127139
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127139 All targets in OG5_127139
Schistosoma japonicum Calpain-1 catalytic subunit, putative Get druggable targets OG5_127139 All targets in OG5_127139
Schistosoma japonicum ko:K08585 calpain, invertebrate, putative Get druggable targets OG5_127139 All targets in OG5_127139
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus calpain A calpain 1, (mu/I) large subunit 714 aa 753 aa 31.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum importin beta, putative 0.0028 0.0134 0.0132
Schistosoma mansoni transient receptor potential channel 0.0272 0.1947 0.3835
Brugia malayi calpain family protein 1 0.0066 0.0412 0.1625
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.004 0.008
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0136 0.0267
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.1006 0.9955
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0351 0.2536 1
Brugia malayi latrophilin 2 splice variant baaae 0.024 0.1709 0.6739
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0136 0.0449
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Echinococcus granulosus voltage gated hydrogen channel 1 0.0014 0.0024 0.0044
Mycobacterium leprae Probable lipase LipE 0.0112 0.0756 0.7379
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0049 0.0285 0.0283
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0002 0.0004
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0051 0.0074
Treponema pallidum glycyl-tRNA synthetase 0.0011 0.0002 0.0002
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0622 0.1221
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0098 0.0649 0.1275
Schistosoma mansoni smad1 5 8 and 0.0016 0.004 0.008
Schistosoma mansoni hypothetical protein 0.0029 0.0136 0.0267
Entamoeba histolytica hypothetical protein 0.0071 0.0452 0.1759
Echinococcus multilocularis sodium leak channel non selective protein 0.0014 0.0024 0.0044
Schistosoma mansoni voltage-gated ion channel 0.0014 0.0024 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.093 0.1829
Treponema pallidum fructose-bisphosphate aldolase 0.0298 0.2141 1
Echinococcus granulosus geminin 0.0692 0.5076 1
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.0104 0.0102
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.0011 0.0002 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0069 0.0135
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0078 0.0114
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0025 0.0107 0.1392
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0018 0.0056 0.0106
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0024 0.0048
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0094 0.1216
Brugia malayi MH2 domain containing protein 0.0233 0.1659 0.654
Entamoeba histolytica hypothetical protein 0.0035 0.0182 0.0702
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0024 0.0033
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0014 0.0024 0.0095
Schistosoma mansoni protein kinase 0.0098 0.0649 0.1279
Trichomonas vaginalis esterase, putative 0.0112 0.0756 0.3287
Brugia malayi Aspartyl-tRNA synthetase 0.0011 0.0002 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0256 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0051 0.0049
Loa Loa (eye worm) beta-lactamase 0.0112 0.0756 0.2529
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0173 0.1367
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0069 0.0135
Mycobacterium ulcerans integral membrane transport protein 0.0045 0.0256 0.2519
Echinococcus multilocularis Smad4 0.0016 0.004 0.0076
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0672 0.067
Onchocerca volvulus 0.0045 0.0256 0.1393
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0024 0.0044
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0356 0.1405
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.0104 0.0398
Schistosoma mansoni ran 0.0021 0.0078 0.0153
Entamoeba histolytica hypothetical protein 0.0023 0.0094 0.0358
Chlamydia trachomatis thioredoxin reductase 0.0146 0.101 1
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0045 0.0256 0.0501
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0069 0.0661
Loa Loa (eye worm) voltage-dependent calcium channel 0.0014 0.0024 0.0074
Brugia malayi hypothetical protein 0.0014 0.0024 0.0095
Loa Loa (eye worm) hypothetical protein 0.0058 0.0356 0.1189
Trypanosoma cruzi hexose transporter, putative 0.0099 0.0659 0.8706
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.2181 0.731
Plasmodium falciparum protein kinase 7 0.0901 0.6631 0.663
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2141 0.9322
Schistosoma mansoni ryanodine receptor related 0.0014 0.0025 0.0048
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0018 0.0056 0.016
Entamoeba histolytica hypothetical protein 0.0101 0.0673 0.2622
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0096 0.0634 0.125
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0024 0.0074
Trichomonas vaginalis glucose transporter, putative 0.0099 0.0659 0.2861
Brugia malayi hypothetical protein 0.0035 0.0182 0.0717
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0134 0.1747
Trypanosoma brucei THT1 - hexose transporter, putative 0.0099 0.0659 0.8706
Loa Loa (eye worm) hypothetical protein 0.0096 0.0634 0.2121
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0756 0.3287
Loa Loa (eye worm) hypothetical protein 0.0112 0.0756 0.2529
Loa Loa (eye worm) hypothetical protein 0.0029 0.0141 0.0467
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0069 0.0883
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0014 0.0024 0.0044
Mycobacterium ulcerans sugar transporter 0.0045 0.0256 0.2519
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0016 0.004 0.0058
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.004 0.0076
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0002 0.0004
Entamoeba histolytica hypothetical protein 0.0035 0.0182 0.0702
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0111 0.0749 0.2954
Echinococcus granulosus pyruvate kinase 0.0017 0.0051 0.0096
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0025 0.0107 0.1392
Brugia malayi MH2 domain containing protein 0.0016 0.004 0.0159
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0025 0.0107 0.1392
Echinococcus granulosus smad 0.0016 0.004 0.0076
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0098 0.0649 0.2171
Echinococcus granulosus dna polymerase eta 0.002 0.0069 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0014 0.0024 0.0095
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0018 0.0056 0.0234
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0024 0.0044
Echinococcus granulosus pyruvate kinase 0.0034 0.0173 0.0336
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0173 0.0254
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0024 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2141 0.9322
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0649 0.1275
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0014 0.0024 0.0095
Loa Loa (eye worm) hypothetical protein 0.0018 0.0056 0.018
Trichomonas vaginalis ran, putative 0.0021 0.0078 0.0331
Onchocerca volvulus 0.0112 0.0756 0.4398
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0014 0.0024 0.0095
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0002 0.0004
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0094 0.04
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.0504 0.6652
Onchocerca volvulus 0.0045 0.0256 0.1393
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0024 0.0044
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0285 0.0558
Echinococcus multilocularis sodium channel protein 0.0014 0.0024 0.0044
Echinococcus granulosus pyruvate kinase 0.0017 0.0051 0.0096
Mycobacterium ulcerans hypothetical protein 0.0016 0.004 0.0378
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0096 0.0634 0.1246
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.145 0.4855
Loa Loa (eye worm) hypothetical protein 0.0098 0.0649 0.2171
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0111 0.0749 0.1472
Schistosoma mansoni protein kinase 0.0098 0.0649 0.1279
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0014 0.0024 0.0294
Plasmodium vivax importin-beta 2, putative 0.0028 0.0134 0.0132
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0024 0.0048
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.0756 0.1374
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0883
Brugia malayi calpain 5 0.0017 0.0051 0.0203
Loa Loa (eye worm) calpain family protein 1 0.0048 0.0283 0.0942
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.0756 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0356 0.1189
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0319 0.2297 0.4522
Onchocerca volvulus 0.0045 0.0256 0.1393
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0183 0.0357
Echinococcus multilocularis dna polymerase eta 0.002 0.0069 0.0131
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0112 0.0753 0.9952
Trypanosoma brucei glucose transporter, putative 0.0099 0.0659 0.8706
Plasmodium falciparum pyruvate kinase 0.0034 0.0173 0.0171
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.004 0.0506
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0018 0.0056 0.018
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0056 0.0712
Schistosoma mansoni pyruvate kinase 0.0034 0.0173 0.034
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0025 0.0107 0.1392
Echinococcus multilocularis musashi 0.0058 0.0356 0.0698
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0014 0.0024 0.0044
Onchocerca volvulus 0.0156 0.1085 0.6371
Brugia malayi hypothetical protein 0.0078 0.0504 0.1986
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0024 0.0048
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0756 0.1489
Brugia malayi calpain 7 0.0025 0.0107 0.0422
Trichomonas vaginalis sugar transporter, putative 0.0099 0.0659 0.2861
Echinococcus multilocularis solute carrier family 22 0.0045 0.0256 0.0501
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0014 0.0024 0.0044
Schistosoma mansoni DNA polymerase eta 0.002 0.0069 0.0135
Brugia malayi Bromodomain containing protein 0.0029 0.0136 0.0535
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus multilocularis GPCR, family 2 0.0111 0.0749 0.1472
Echinococcus granulosus voltage dependent calcium channel 0.0014 0.0024 0.0044
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0014 0.0024 0.0048
Brugia malayi MH1 domain containing protein 0.0016 0.004 0.0159
Schistosoma mansoni ran 0.0021 0.0078 0.0153
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0024 0.0048
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0024 0.0048
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0002 0.0005
Echinococcus multilocularis calpain 0.0025 0.0107 0.0207
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0069 0.0883
Loa Loa (eye worm) hypothetical protein 0.0041 0.0227 0.0756
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0285 0.3758
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0078 0.0076
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0024 0.0044
Echinococcus multilocularis calcium dependent protein kinase 0.0092 0.0604 0.1187
Plasmodium vivax calpain, putative 0.0025 0.0107 0.0105
Brugia malayi voltage-dependent calcium channel 0.0014 0.0024 0.0095
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0002 0.0005
Loa Loa (eye worm) major facilitator superfamily transporter 0.0045 0.0256 0.0852
Chlamydia trachomatis histidine--tRNA ligase 0.0011 0.0002 0.0003
Echinococcus granulosus calpain 5 0.0025 0.0107 0.0207
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0141 0.0274
Schistosoma mansoni calpain C (C02 family) 0.0025 0.0107 0.0211
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0354 0.2561 1
Echinococcus granulosus sodium channel protein 0.0014 0.0024 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0659 0.2861
Loa Loa (eye worm) hypothetical protein 0.024 0.1709 0.5726
Echinococcus multilocularis glycyl tRNA synthetase 0.0018 0.0056 0.0106
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Echinococcus granulosus calcium dependent protein kinase 0.0092 0.0604 0.1187
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0182 0.0358
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0024 0.0048
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0014 0.0024 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2141 0.9322
Giardia lamblia Pyruvate kinase 0.0034 0.0173 0.0667
Leishmania major lysyl-tRNA synthetase, putative 0.0071 0.0452 0.5969
Schistosoma mansoni lysyl-tRNA synthetase 0.0071 0.0452 0.0891
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0014 0.0025 0.0097
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0014 0.0024 0.0044
Echinococcus granulosus calpain 0.0025 0.0107 0.0207
Trypanosoma brucei sugar transporter, putative 0.0045 0.0256 0.3368
Brugia malayi hypothetical protein 0.005 0.0298 0.1173
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0097 0.0318
Trypanosoma brucei histidyl-tRNA synthetase 0.0011 0.0002 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Trypanosoma brucei glucose transporter, putative 0.0099 0.0659 0.8706
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Mycobacterium tuberculosis Conserved protein 0.0112 0.0756 0.1374
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0014 0.0024 0.0044
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0183 0.0357
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0025 0.0107 0.1392
Onchocerca volvulus 0.0045 0.0256 0.1393
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0014 0.0024 0.0048
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0094 0.04
Loa Loa (eye worm) hypothetical protein 0.0153 0.1061 0.3551
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Plasmodium falciparum hexose transporter 0.0319 0.2297 0.2295
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0098 0.0649 0.1275
Brugia malayi Sugar transporter family protein 0.0319 0.2297 0.9056
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0112 0.0753 0.9952
Loa Loa (eye worm) hypothetical protein 0.0112 0.0756 0.2529
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0025 0.0107 0.1392
Leishmania major glucose transporter, lmgt1 0.0099 0.0659 0.8706
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0024 0.0044
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0285 0.0558
Onchocerca volvulus 0.0058 0.0356 0.1996
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0024 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Schistosoma mansoni hypothetical protein 0.0692 0.5076 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.0098 0.065 0.0648
Brugia malayi Pre-SET motif family protein 0.0205 0.145 0.5716
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0141 0.0278
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2141 0.9322
Echinococcus granulosus Sugar transporter ERD6 protein 0.0045 0.0256 0.0501
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.0756 0.7479
Entamoeba histolytica calpain large subunit domain III containing protein 0.0017 0.0051 0.0193
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0024 0.0033
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0173 0.0258
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.006 0.0372 0.0637
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0883
Echinococcus granulosus Smad4 0.0016 0.004 0.0076
Trypanosoma brucei glucose transporter 1E 0.0099 0.0659 0.8706
Toxoplasma gondii facilitative glucose transporter GT1 0.0319 0.2297 0.3462
Onchocerca volvulus 0.0045 0.0256 0.1393
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0011 0.0002 0.0002
Toxoplasma gondii sugar transporter ST3 0.0045 0.0256 0.0383
Trypanosoma brucei calpain-like protein, putative 0.0025 0.0107 0.1392
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0318
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0024 0.0044
Leishmania major myo-inositol/proton symporter (MIT) 0.0045 0.0256 0.3368
Leishmania major GTP-binding protein, putative 0.0021 0.0078 0.1006
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0515 0.3759 0.3758
Echinococcus multilocularis synaptic vesicle 2 protein 0.0045 0.0256 0.0501
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0023 0.028
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0146 0.101 0.4395
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0056 0.0712
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0018 0.0056 0.022
Echinococcus multilocularis pyruvate kinase 0.0034 0.0173 0.0336
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0014 0.0024 0.0044
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0024 0.0048
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.0104 0.1352
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0256 0.1009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0173 0.2264
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0025 0.0107 0.1392
Echinococcus granulosus synaptic vesicle 2 protein 0.0045 0.0256 0.0501
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0025 0.0107 0.1392
Brugia malayi hypothetical protein 0.0045 0.0256 0.1009
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0173 0.2264
Onchocerca volvulus 0.0054 0.0322 0.1789
Plasmodium falciparum lysine--tRNA ligase 0.0071 0.0452 0.045
Schistosoma mansoni hypothetical protein 0.0111 0.0749 0.1476
Trypanosoma cruzi hexose transporter, putative 0.0045 0.0256 0.3368
Echinococcus granulosus tumor protein p63 0.0367 0.2653 0.5225
Giardia lamblia DNA repair protein RAD52 0.0354 0.2561 1
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0478 0.0942
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0173 0.2264
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0096 0.0634 0.125
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.004 0.0076
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0011 0.0008 0.0073
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Onchocerca volvulus 0.0112 0.0756 0.4398
Toxoplasma gondii hypothetical protein 0.0014 0.0024 0.0033
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0025 0.0107 0.1392
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0014 0.0024 0.0095
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0024 0.0044
Brugia malayi Pre-SET motif family protein 0.0029 0.0141 0.0557
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0134 0.1747
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0135 0.093 0.3113
Echinococcus multilocularis short transient receptor potential channel 6 0.0272 0.1947 0.3833
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0173 0.0573
Echinococcus granulosus lamin 0.0058 0.0356 0.0698
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0024 0.0044
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0173 0.0744
Echinococcus multilocularis General substrate transporter 0.0274 0.1963 0.3864
Brugia malayi major facilitator superfamily protein 0.0045 0.0256 0.1009
Toxoplasma gondii transporter, major facilitator family protein 0.0045 0.0256 0.0383
Echinococcus granulosus solute carrier family 22 0.0045 0.0256 0.0501
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Schistosoma mansoni hypothetical protein 0.0014 0.0024 0.0048
Plasmodium vivax sugar transporter, putative 0.0045 0.0256 0.0254
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0014 0.0024 0.0044
Schistosoma mansoni hypothetical protein 0.0319 0.2297 0.4524
Leishmania major protein kinase, putative 0.0098 0.0649 0.8582
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0098 0.0649 0.2171
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0018 0.0056 0.021
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0285 0.3758
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0173 0.0893
Schistosoma mansoni transient receptor potential channel 4 0.0411 0.2983 0.5877
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.004 0.0076
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0356 0.1189
Echinococcus multilocularis tumor protein p63 0.0367 0.2653 0.5225
Plasmodium falciparum mitogen-activated protein kinase 2 0.0515 0.3759 0.3758
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0319 0.2297 0.4522
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Brugia malayi Importin beta-1 subunit 0.0028 0.0134 0.0527
Brugia malayi hypothetical protein 0.0045 0.0256 0.1009
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0023 0.028
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0014 0.0024 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0256 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0256 0.1107
Echinococcus granulosus intermediate filament protein 0.0058 0.0356 0.0698
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.004 0.0129
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0319 0.2297 0.4522
Schistosoma mansoni hypothetical protein 0.0035 0.0182 0.0358
Leishmania major DNA polymerase eta, putative 0.002 0.0069 0.0883
Brugia malayi Transient-receptor-potential like protein 0.0153 0.1061 0.4182
Trypanosoma brucei unspecified product 0.002 0.0069 0.0883
Echinococcus multilocularis voltage dependent calcium channel 0.0014 0.0024 0.0044
Brugia malayi PHD-finger family protein 0.0029 0.0136 0.0535
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0173 0.0893
Trypanosoma brucei kinesin, putative 0.0017 0.0051 0.0655
Echinococcus multilocularis transfer RNA-Gly 0.0014 0.0024 0.0044
Chlamydia trachomatis lysine--tRNA ligase 0.0071 0.0452 0.4464
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0146 0.101 0.4395
Echinococcus multilocularis conserved hypothetical protein 0.0014 0.0024 0.0044
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0069 0.0055
Trypanosoma brucei calpain-like protein, putative 0.0025 0.0107 0.1392
Giardia lamblia Hexose transporter 0.0045 0.0256 0.0992
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0141 0.0278
Brugia malayi beta-lactamase family protein 0.0112 0.0756 0.2981
Loa Loa (eye worm) hypothetical protein 0.0139 0.0959 0.3209
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.004 0.0129
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.004 0.0506
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0018 0.0056 0.0712
Schistosoma mansoni sugar transporter 0.0045 0.0256 0.0504
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0024 0.0044
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.0024 0.0044
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.0756 0.1374
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0756 1
Leishmania major hypothetical protein, conserved 0.0112 0.0756 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0014 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0096 0.0634 0.2502
Schistosoma mansoni importin beta-1 0.0028 0.0134 0.0263
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0104 0.041
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0024 0.0044
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0319 0.2297 0.4522
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0173 0.0893
Schistosoma mansoni smad 0.0016 0.004 0.008
Plasmodium falciparum threonine--tRNA ligase 0.0018 0.0056 0.0054
Trypanosoma brucei glucose transporter, putative 0.0099 0.0659 0.8706
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0018 0.0056 0.0712
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0756 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0024 0.0048
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0034 0.0174 0.1703
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.093 0.1829
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Onchocerca volvulus 0.0045 0.0256 0.1393
Loa Loa (eye worm) hypothetical protein 0.0029 0.0136 0.0449
Toxoplasma gondii sugar transporter ST1 0.0045 0.0256 0.0383
Onchocerca volvulus 0.0045 0.0256 0.1393
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0096 0.0634 0.2121
Plasmodium falciparum calcium-dependent protein kinase 4 0.0098 0.065 0.0648
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0014 0.0024 0.0095
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0045 0.0256 0.0414
Echinococcus granulosus histidyl tRNA synthetase 0.0011 0.0002 0.0001
Schistosoma mansoni 60S ribosomal protein L21 0.0014 0.0024 0.0048
Onchocerca volvulus 0.0041 0.0227 0.1221
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2141 0.9322
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0319 0.2297 0.4522
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0024 0.0048
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0069 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.004 0.0166
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0049 0.0285 0.0562
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0024 0.0044
Schistosoma mansoni calpain (C02 family) 0.0025 0.0107 0.0211
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0014 0.0024 0.0044
Schistosoma mansoni calcium-activated potassium channel 0.0014 0.0024 0.0048
Brugia malayi beta-lactamase 0.0112 0.0756 0.2981
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0096 0.0634 0.2502
Loa Loa (eye worm) hypothetical protein 0.0034 0.0173 0.0573
Brugia malayi olfactory channel protein osm-9 0.0014 0.0024 0.0095
Loa Loa (eye worm) pax transcription factor protein 2 0.0237 0.1689 0.5657
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Plasmodium vivax threonine--tRNA ligase, putative 0.0018 0.0056 0.0054
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0715 0.5251 1
Schistosoma mansoni vesicular amine transporter 0.0014 0.0024 0.0048
Treponema pallidum prolyl-tRNA synthetase 0.0034 0.0174 0.0803
Brugia malayi cation channel family protein 0.0014 0.0024 0.0095
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.2141 0.8357
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0069 0.0883
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0173 0.0573
Loa Loa (eye worm) hypothetical protein 0.0049 0.0288 0.0961
Entamoeba histolytica protein kinase, putative 0.0023 0.0097 0.037
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0049 0.0285 0.3758
Leishmania major hypothetical protein, conserved 0.0078 0.0504 0.6652
Echinococcus multilocularis solute carrier family 22 0.0045 0.0256 0.0501
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.0504 0.0502
Trichomonas vaginalis set domain proteins, putative 0.0233 0.1661 0.7228
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0018 0.0056 0.021
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Toxoplasma gondii ABC1 family protein 0.0112 0.0756 0.1138
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0155 0.0512
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0181 0.0352
Trypanosoma cruzi hexose transporter, putative 0.0054 0.0325 0.4278
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Trypanosoma brucei calpain-like protein, putative 0.0025 0.0107 0.1392
Leishmania major glycyl tRNA synthetase, putative 0.0011 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0078 0.1006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0134 0.0442
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0078 0.0296
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0024 0.0097
Onchocerca volvulus 0.0237 0.1689 1
Brugia malayi ion channel NompC 0.0014 0.0024 0.0095
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0071 0.0452 0.4464
Schistosoma mansoni sugar transporter 0.0045 0.0256 0.0504
Trypanosoma brucei THT1 - hexose transporter, putative 0.0099 0.0659 0.8706
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0045 0.0256 0.3368
Trypanosoma cruzi hexose transporter 0.0099 0.0659 0.8706
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0045 0.0256 0.0414
Echinococcus granulosus pyruvate kinase 0.0034 0.0173 0.0336
Echinococcus granulosus solute carrier family 22 0.0045 0.0256 0.0501
Echinococcus multilocularis smad 0.0016 0.004 0.0076
Schistosoma mansoni hypothetical protein 0.0692 0.5076 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.1006 0.1854
Echinococcus multilocularis calcium activated potassium channel 0.002 0.007 0.0133
Onchocerca volvulus Alhambra homolog 0.0029 0.0136 0.067
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0014 0.0024 0.0044
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0014 0.0024 0.0095
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0756 0.0754
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0014 0.0024 0.0095
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0111 0.0749 0.1472
Trypanosoma brucei THT1 - hexose transporter, putative 0.0099 0.0659 0.8706
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0024 0.0044
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0107 0.0211
Echinococcus multilocularis snurportin 1 0.0303 0.2181 0.4295
Toxoplasma gondii hypothetical protein 0.0014 0.0024 0.0033
Schistosoma mansoni sugar transporter 0.0045 0.0256 0.0504
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.0756 0.2981
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0018 0.0056 0.0532
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0098 0.065 0.0977
Schistosoma mansoni voltage-dependent calcium channel 0.0014 0.0024 0.0048
Plasmodium falciparum calcium-dependent protein kinase 1 0.0098 0.065 0.0648
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0133 0.0258
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0024 0.0044
Echinococcus multilocularis short transient receptor potential channel 6 0.0272 0.1947 0.3833
Echinococcus multilocularis pyruvate kinase 0.0017 0.0051 0.0096
Echinococcus multilocularis muscleblind protein 1 0.0152 0.1056 0.2077
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0024 0.0097
Echinococcus multilocularis two pore calcium channel protein 1 0.0014 0.0024 0.0044
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0155 0.061
Brugia malayi Latrophilin receptor protein 2 0.0111 0.0749 0.2954
Echinococcus granulosus pyruvate kinase 0.0017 0.0051 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0285 0.0558
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0111 0.0749 0.1472
Brugia malayi RNA, U transporter 1 0.0081 0.0524 0.2066
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0024 0.0044
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0014 0.0024 0.0095
Onchocerca volvulus 0.0029 0.0141 0.0703
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Loa Loa (eye worm) hypothetical protein 0.0112 0.0756 0.2529
Loa Loa (eye worm) calpain family protein 1 0.0066 0.0412 0.1376
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0098 0.0649 0.256
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0659 0.2861
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0112 0.0753 0.1132
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0024 0.0044
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0069 0.0661
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0285 0.3758
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0069 0.0271
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Loa Loa (eye worm) MH2 domain-containing protein 0.0233 0.1659 0.5556
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0223
Schistosoma mansoni protein kinase 0.0098 0.0649 0.1279
Brugia malayi jmjC domain containing protein 0.0035 0.0181 0.0713
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0018 0.0056 0.022
Schistosoma mansoni hypothetical protein 0.0111 0.0749 0.1476
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0062 0.0387 0.1677
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0014 0.0024 0.0044
Echinococcus multilocularis transient receptor potential gamma protein 0.0411 0.2983 0.5875
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.0756 0.1374
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0014 0.0024 0.0044
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0071 0.0452 0.5969
Plasmodium vivax calcium-dependent protein kinase, putative 0.0098 0.065 0.0648
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0136 0.0264
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0351 0.2536 0.85
Schistosoma mansoni calpain-7 (C02 family) 0.0025 0.0107 0.0211
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.004 0.0076
Mycobacterium tuberculosis Conserved protein 0.0112 0.0756 0.1374
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0014 0.0024 0.0095
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.093 0.1832
Schistosoma mansoni glucose transport protein 0.0319 0.2297 0.4524
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0014 0.0024 0.0095
Echinococcus multilocularis calpain 5 0.0025 0.0107 0.0207
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0146 0.101 1
Brugia malayi major facilitator superfamily protein 0.0045 0.0256 0.1009
Echinococcus granulosus calcium activated potassium channel 0.002 0.007 0.0133
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0104 0.041
Leishmania major hypothetical protein, conserved 0.0016 0.004 0.0506
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0078 0.015
Schistosoma mansoni lamin 0.0058 0.0356 0.0702
Echinococcus granulosus TRP transient receptor potential channel 0.0153 0.1061 0.2086
Loa Loa (eye worm) ryanodine receptor 0.0014 0.0024 0.0074
Loa Loa (eye worm) hypothetical protein 0.0054 0.0322 0.1073
Schistosoma mansoni glucose transport protein 0.0319 0.2297 0.4524
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0014 0.0024 0.0048
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0002 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0649 0.1279
Schistosoma mansoni hypothetical protein 0.0111 0.0749 0.1476
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0078 0.0076
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus multilocularis voltage dependent calcium channel 0.0014 0.0024 0.0044
Schistosoma mansoni intermediate filament proteins 0.0058 0.0356 0.0702
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0025 0.0107 0.1392
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0011 0.0002 0.0002
Echinococcus multilocularis calpain A 0.0069 0.0434 0.0852
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.006 0.0372 0.3423
Loa Loa (eye worm) hypothetical protein 0.0112 0.0756 0.2529
Schistosoma mansoni hypothetical protein 0.0303 0.2181 0.4297
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.0104 0.1352
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0285 0.0427
Brugia malayi cation channel family protein 0.0014 0.0024 0.0095
Brugia malayi Isocitrate dehydrogenase 0.0049 0.0285 0.1125
Onchocerca volvulus 0.0045 0.0256 0.1393
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0024 0.0044
Schistosoma mansoni hypothetical protein 0.0035 0.0183 0.036
Plasmodium falciparum calcium-dependent protein kinase 2 0.0098 0.065 0.0648
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0181 0.0356
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0024 0.0033
Trypanosoma brucei glucose transporter 2A 0.0099 0.0659 0.8706
Brugia malayi Pax transcription factor protein 2 0.0237 0.1689 0.6658
Plasmodium falciparum phd finger protein, putative 0.0029 0.0136 0.0134
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0182 0.0354
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0098 0.065 0.0977
Loa Loa (eye worm) hypothetical protein 0.0258 0.1845 0.6181
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0112 0.0753 0.9952
Onchocerca volvulus 0.0045 0.0256 0.1393
Chlamydia trachomatis pyruvate kinase 0.0034 0.0173 0.1693
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Loa Loa (eye worm) Smad1 0.0016 0.004 0.0129
Brugia malayi beta-lactamase family protein 0.0112 0.0756 0.2981
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0025 0.0107 0.1392
Schistosoma mansoni transient receptor potential channel 0.0272 0.1947 0.3835
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0024 0.0074
Loa Loa (eye worm) calpain 5 0.0017 0.0051 0.0166
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0014 0.0024 0.0048
Echinococcus multilocularis geminin 0.0692 0.5076 1
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0883
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Echinococcus granulosus snurportin 1 0.0303 0.2181 0.4295
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0049 0.0285 0.3758
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0069 0.0271
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0096 0.0634 0.2471
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0319 0.2297 0.4522
Leishmania major pyruvate kinase 0.0034 0.0173 0.2264
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Giardia lamblia Thioredoxin reductase 0.0146 0.101 0.394
Echinococcus granulosus short transient receptor potential channel 6 0.0272 0.1947 0.3833
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0096 0.0634 0.6126
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.006 0.0372 0.0637
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0649 0.1275
Mycobacterium ulcerans hypothetical protein 0.0112 0.0756 0.7479
Onchocerca volvulus 0.0233 0.1661 0.9832
Echinococcus granulosus transient receptor potential ion channel A 0.0397 0.2881 0.5674
Loa Loa (eye worm) hypothetical protein 0.0071 0.0452 0.151
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0014 0.0024 0.0095
Schistosoma mansoni glucose transporter 0.0045 0.0256 0.0504
Treponema pallidum threonyl-tRNA synthetase 0.0018 0.0056 0.0251
Onchocerca volvulus 0.0045 0.0256 0.1393
Leishmania major glucose transporter, lmgt2 0.0099 0.0659 0.8706
Echinococcus multilocularis solute carrier family 22 0.0045 0.0256 0.0501
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0256 0.1107
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0146 0.101 0.4395
Echinococcus multilocularis pyruvate kinase 0.0017 0.0051 0.0096
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0071 0.0452 0.4246
Brugia malayi MH1 domain containing protein 0.0016 0.004 0.0159
Echinococcus granulosus calpain 7 C02 family 0.0025 0.0107 0.0207
Onchocerca volvulus 0.0045 0.0256 0.1393
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0412 0.0812
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0069 0.0434 0.0856
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0069 0.026
Plasmodium falciparum calcium-dependent protein kinase 5 0.0098 0.065 0.0648
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0014 0.0024 0.0044
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.0104 0.0201
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0045 0.0256 0.0254
Loa Loa (eye worm) hypothetical protein 0.0028 0.0132 0.0435
Entamoeba histolytica hypothetical protein 0.0035 0.0182 0.0702
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.0104 0.0154
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0045 0.0256 0.2519
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0504 0.0502
Onchocerca volvulus 0.0112 0.0756 0.4398
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Schistosoma mansoni voltage-gated cation channel 0.0014 0.0024 0.0048
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0098 0.065 0.0648
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2141 0.9322
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus granulosus potassium large conductance calcium activated 0.0014 0.0024 0.0044
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0024 0.0044
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0018 0.0056 0.018
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0014 0.0024 0.0044
Brugia malayi Calcitonin receptor-like protein seb-1 0.0351 0.2536 1
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0024 0.0044
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.0104 0.1352
Giardia lamblia Fructose-bisphosphate aldolase 0.0298 0.2141 0.8357
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Echinococcus multilocularis lamin dm0 0.0058 0.0356 0.0698
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.0756 0.2529
Mycobacterium ulcerans lipase LipD 0.0112 0.0756 0.7479
Brugia malayi Cam kinase protein 1 0.0098 0.0649 0.256
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0018 0.0056 0.0532
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.093 0.1829
Schistosoma mansoni hypothetical protein 0.024 0.1709 0.3367
Echinococcus granulosus lamin dm0 0.0058 0.0356 0.0698
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0319 0.2297 0.4522
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0319 0.2297 0.4522
Loa Loa (eye worm) voltage-gated calcium channel 0.0014 0.0024 0.0074
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0069 0.0434 0.0852
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0181 0.0356
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.0756 0.1374
Loa Loa (eye worm) hypothetical protein 0.0058 0.0357 0.1189
Echinococcus granulosus Threonyl tRNA synthetase C 0.0018 0.0056 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.004 0.0166
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0024 0.0048
Loa Loa (eye worm) calcium channel 0.0014 0.0024 0.0074
Toxoplasma gondii lysine-tRNA ligase 0.0071 0.0452 0.0679
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0011 0.0002 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Leishmania major hypothetical protein, conserved 0.0016 0.004 0.0506
Loa Loa (eye worm) hypothetical protein 0.0152 0.1056 0.3536
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0256 0.1009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0124 0.0408
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0078 0.0501 0.1673
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0136 0.0134
Loa Loa (eye worm) sugar transporter 0.0319 0.2297 0.7696
Echinococcus granulosus two pore calcium channel protein 1 0.0014 0.0024 0.0044
Echinococcus multilocularis transient receptor potential ion channel A 0.0397 0.2881 0.5674
Echinococcus multilocularis lamin 0.0058 0.0356 0.0698
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0025 0.0107 0.1392
Echinococcus granulosus calpain A 0.0025 0.0107 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0319 0.2297 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0181 0.0352
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0069 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0649 0.2821
Toxoplasma gondii protein kinase, putative 0.0901 0.6631 1
Schistosoma mansoni pyruvate kinase 0.0034 0.0173 0.034
Loa Loa (eye worm) hypothetical protein 0.0066 0.0412 0.1376
Giardia lamblia DINP protein human, muc B family 0.002 0.0069 0.026
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0025 0.0107 0.1392
Giardia lamblia Threonyl-tRNA synthetase 0.0018 0.0056 0.021
Echinococcus multilocularis dna polymerase kappa 0.002 0.0069 0.0131
Mycobacterium tuberculosis Conserved protein 0.0112 0.0756 0.1374
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0173 0.1693
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.0104 0.0102
Onchocerca volvulus 0.0045 0.0256 0.1393
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0756 0.3287
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0014 0.0024 0.0294
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.0756 0.1374
Plasmodium vivax proline--tRNA ligase, putative 0.0112 0.0753 0.0751
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0018 0.0056 0.003
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0024 0.0044
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0045 0.0256 0.2519
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0014 0.0024 0.0044
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.004 0.0506
Plasmodium vivax hexose transporter 0.0319 0.2297 0.2295
Chlamydia trachomatis threonine--tRNA ligase 0.0018 0.0056 0.0532
Leishmania major importin beta-1 subunit, putative 0.0023 0.0094 0.1216
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0363 0.1212
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0756 0.3287
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0014 0.0024 0.0294
Loa Loa (eye worm) hypothetical protein 0.0351 0.2536 0.85
Echinococcus granulosus peregrin 0.0029 0.0136 0.0264
Schistosoma mansoni hypothetical protein 0.0111 0.0749 0.1476
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0173 0.0573
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0069 0.029
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0104 0.0205
Schistosoma mansoni pyruvate kinase 0.0017 0.0051 0.01
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.2141 0.8357
Brugia malayi Smad1 0.0016 0.004 0.0159
Schistosoma mansoni threonyl-tRNA synthetase 0.0011 0.0002 0.0005
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0024 0.0074
Brugia malayi isocitrate dehydrogenase 0.0049 0.0285 0.1125
Echinococcus multilocularis calpain family protein 1, d 0.0048 0.0283 0.0554
Loa Loa (eye worm) T-complex protein 1 0.0024 0.0104 0.0342
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.093 0.1832
Trypanosoma brucei glucose transporter, putative 0.0099 0.0659 0.8706
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0135 0.093 0.3668
Brugia malayi Muscleblind-like protein 0.0152 0.1056 0.4165
Toxoplasma gondii sugar transporter ST2 0.0045 0.0256 0.0383
Echinococcus granulosus lysyl tRNA synthetase 0.0071 0.0452 0.0887
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0011 0.0002 0.0003
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0173 0.0744
Trichomonas vaginalis myo-inositol transporter, putative 0.0045 0.0256 0.1107
Echinococcus granulosus glycyl tRNA synthetase 0.0018 0.0056 0.0106
Echinococcus multilocularis two pore calcium channel protein 2 0.0014 0.0024 0.0044
Echinococcus granulosus importin subunit beta 1 0.0028 0.0134 0.026
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0002 0.0005
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.0104 0.0444
Echinococcus multilocularis potassium large conductance calcium activated 0.0014 0.0024 0.0044
Giardia lamblia PHD finger protein 15 0.0029 0.0136 0.0523
Echinococcus granulosus solute carrier family 22 0.0045 0.0256 0.0501
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0146 0.101 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0504 0.1683
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0141 0.0274
Loa Loa (eye worm) hypothetical protein 0.0152 0.1056 0.3536
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0101 0.0673 0.2622
Schistosoma mansoni glycyl-tRNA synthetase 0.0018 0.0056 0.011
Brugia malayi hypothetical protein 0.0156 0.1085 0.4277
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0018 0.0056 0.0532
Trypanosoma brucei unspecified product 0.0014 0.0023 0.028
Leishmania major hypothetical protein, unknown function 0.0014 0.0024 0.0294
Echinococcus multilocularis shaker cognate 0.0014 0.0024 0.0044
Echinococcus granulosus solute carrier family 22 0.0045 0.0256 0.0501
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0018 0.0056 0.0081
Schistosoma mansoni two-pore calcium channel 0.0014 0.0024 0.0048
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0024 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0023 0.028
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0002 0.0004
Loa Loa (eye worm) isocitrate dehydrogenase 0.0049 0.0285 0.095
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0182 0.0354
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0014 0.0024 0.0044
Giardia lamblia Pyruvate kinase 0.0017 0.0051 0.019
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0025 0.0107 0.1392
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.004 0.0506
Echinococcus multilocularis muscleblind protein 0.0152 0.1056 0.2077
Trypanosoma cruzi glucose transporter, putative 0.0045 0.0256 0.3368
Entamoeba histolytica protein kinase, putative 0.0098 0.0649 0.2529
Echinococcus granulosus calpain A 0.0069 0.0434 0.0852
Echinococcus multilocularis lysyl tRNA synthetase 0.0071 0.0452 0.0887
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Trichomonas vaginalis sugar transporter, putative 0.0099 0.0659 0.2861
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0097 0.0371
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0098 0.0649 0.1275
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0024 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2141 0.9322
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0024 0.0044
Echinococcus granulosus ryanodine receptor 44f 0.0014 0.0025 0.0045
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0024 0.0044
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0024 0.0044
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0045 0.0256 0.2519
Trypanosoma brucei glucose transporter, putative 0.0099 0.0659 0.8706
Brugia malayi jmjC domain containing protein 0.0094 0.0622 0.2452
Echinococcus granulosus dna polymerase kappa 0.002 0.0069 0.0131
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Leishmania major hypothetical protein, conserved 0.0014 0.0024 0.0294
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0141 0.0278
Loa Loa (eye worm) transcription factor SMAD2 0.0233 0.1659 0.5556
Treponema pallidum thioredoxin reductase (trxB) 0.0146 0.101 0.4714
Leishmania major pyruvate kinase 0.0034 0.0173 0.2264
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.004 0.0166
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0014 0.0024 0.0095
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0146 0.101 0.4395
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0104 0.0205
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0049 0.0285 0.0558
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus granulosus muscleblind protein 0.0152 0.1056 0.2077
Trypanosoma cruzi kinesin, putative 0.0017 0.0051 0.0655
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0014 0.0024 0.0044
Trypanosoma brucei glucose transporter, putative 0.0099 0.0659 0.8706
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0014 0.0024 0.0048
Onchocerca volvulus 0.0045 0.0256 0.1393
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Echinococcus multilocularis pyruvate kinase 0.0034 0.0173 0.0336
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.1006 0.9957
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0069 0.029
Plasmodium falciparum proline--tRNA ligase 0.0112 0.0753 0.0751
Onchocerca volvulus 0.0058 0.0356 0.1996
Brugia malayi Sugar transporter family protein 0.0045 0.0256 0.1009
Schistosoma mansoni Mername-AA248 (C02 family) 0.0025 0.0107 0.0211
Echinococcus granulosus two pore calcium channel protein 2 0.0014 0.0024 0.0044
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0078 0.1006
Loa Loa (eye worm) ion channel NompC 0.0014 0.0024 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0011 0.0002 0.0001
Entamoeba histolytica thioredoxin reductase, putative 0.0146 0.101 0.394
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0024 0.0044
Trypanosoma cruzi histidyl-tRNA synthetase 0.0011 0.0002 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0504 0.0502
Entamoeba histolytica Ran family GTPase 0.0021 0.0078 0.0296
Brugia malayi lysyl-tRNA synthetase 0.0071 0.0452 0.1783
Giardia lamblia Sugar-proton symporter 0.0045 0.0256 0.0992
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0756 0.3287
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0098 0.065 0.0977
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0024 0.0044
Echinococcus granulosus transient receptor potential gamma protein 0.0411 0.2983 0.5875
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0883
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0014 0.0024 0.0095
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.0024 0.0044
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.0024 0.0074
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0173 0.0171
Echinococcus multilocularis histidyl tRNA synthetase 0.0011 0.0002 0.0001
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0146 0.101 1
Trypanosoma brucei unspecified product 0.0014 0.0023 0.028
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0649 0.1275
Loa Loa (eye worm) hypothetical protein 0.0411 0.2983 1
Mycobacterium leprae conserved hypothetical protein 0.0112 0.0756 0.7379
Onchocerca volvulus 0.0045 0.0256 0.1393
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0111 0.0749 0.1472
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0096 0.0634 0.2756
Loa Loa (eye worm) calpain 0.0025 0.0107 0.0352
Echinococcus multilocularis isocitrate dehydrogenase 0.0049 0.0285 0.0558
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0141 0.021
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0504 0.6652
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Schistosoma mansoni sugar transporter 0.0045 0.0256 0.0504
Brugia malayi glycyl-tRNA synthetase 0.0018 0.0056 0.022
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0024 0.0044
Trypanosoma cruzi hexose transporter, putative 0.0099 0.0659 0.8706
Brugia malayi MH2 domain containing protein 0.0016 0.004 0.0159
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0024 0.0048
Trichomonas vaginalis glucose transporter, putative 0.0045 0.0256 0.1107
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0322 0.0634
Echinococcus granulosus short transient receptor potential channel 6 0.0272 0.1947 0.3833
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0069 0.0434 0.0852
Brugia malayi calpain family protein 1 0.0066 0.0412 0.1625
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0219 0.0428
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0134 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Onchocerca volvulus 0.0045 0.0256 0.1393
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0883
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0173 0.2264
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0014 0.0024 0.0044
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0098 0.065 0.0648
Chlamydia trachomatis proline--tRNA ligase 0.0034 0.0174 0.1703
Leishmania major threonyl-tRNA synthetase, putative 0.0018 0.0056 0.0712
Echinococcus granulosus sodium leak channel non selective protein 0.0014 0.0024 0.0044
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0014 0.0024 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0256 0.1107
Loa Loa (eye worm) hypothetical protein 0.0111 0.0749 0.2506
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0756 0.1489
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.0756 0.1486
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0098 0.0649 0.8582
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0146 0.101 0.1862
Echinococcus granulosus hypothetical protein 0.0014 0.0024 0.0044
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0024 0.0044
Brugia malayi Sugar transporter family protein 0.0045 0.0256 0.1009
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0014 0.0024 0.0044
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0039 0.0215 0.0713
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0883
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0112 0.0753 0.9952
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0146 0.101 0.4395
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Schistosoma mansoni lamin 0.0058 0.0356 0.0702
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Plasmodium vivax SET domain protein, putative 0.0029 0.0141 0.0139
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0024 0.0048
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0098 0.0649 0.1275
Onchocerca volvulus 0.0045 0.0256 0.1393
Entamoeba histolytica hypothetical protein 0.0035 0.0182 0.0702
Giardia lamblia Glycyl-tRNA synthetase 0.0018 0.0056 0.021
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0132 0.0256
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0071 0.0452 0.5969
Trypanosoma brucei glucose transporter, putative 0.0099 0.0659 0.8706
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0002 0.0004
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0071 0.0452 0.4464
Echinococcus granulosus GPCR family 2 0.0111 0.0749 0.1472
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.2141 0.9322
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.093 0.1832
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0069 0.0434 0.0856
Echinococcus multilocularis ryanodine receptor 44f 0.0014 0.0025 0.0045
Loa Loa (eye worm) sugar transporter 0.0045 0.0256 0.0852
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0756 0.3287
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0011 0.0002 0.0001
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0018 0.0056 0.0532
Echinococcus granulosus General substrate transporter 0.0274 0.1963 0.3864
Leishmania major glucose transporter/membrane transporter D2, putative 0.0099 0.0659 0.8706
Leishmania major glucose transporter, lmgt3 0.0099 0.0659 0.8706
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0504 0.6652
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0136 0.0202
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0622 0.1221
Plasmodium vivax lysine--tRNA ligase, putative 0.0071 0.0452 0.045
Trypanosoma brucei antigen, putative 0.0025 0.0107 0.1392
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.093 0.1829
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0078 0.0254
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0014 0.0024 0.0044
Leishmania major histidyl-tRNA synthetase, putative 0.0011 0.0002 0.0005
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0136 0.0264
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.0756 0.7479
Leishmania major hypothetical protein, conserved 0.0045 0.0256 0.3368
Loa Loa (eye worm) hypothetical protein 0.0112 0.0756 0.2529
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0136 0.0202
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0096 0.0634 0.1246
Schistosoma mansoni glucose transport protein 0.0319 0.2297 0.4524
Loa Loa (eye worm) hypothetical protein 0.0027 0.0124 0.0408
Brugia malayi hypothetical protein 0.0045 0.0256 0.1009
Echinococcus granulosus jumonji domain containing protein 0.004 0.0219 0.0428
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.0756 0.1374
Trypanosoma brucei glucose transporter, putative 0.0099 0.0659 0.8706
Echinococcus multilocularis hypothetical protein 0.0025 0.0107 0.0207
Echinococcus multilocularis pyruvate kinase 0.0027 0.012 0.0232
Trichomonas vaginalis sugar transport protein, putative 0.0045 0.0256 0.1107
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0078 0.0307
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0078 0.1006
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0014 0.0024 0.0074
Echinococcus multilocularis solute carrier family 22 0.0045 0.0256 0.0501
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0024 0.0044
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0049 0.0285 0.0283
Loa Loa (eye worm) hypothetical protein 0.0156 0.1085 0.3631
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0883
Trypanosoma cruzi kinesin, putative 0.0017 0.0051 0.0655
Echinococcus multilocularis peregrin 0.0029 0.0136 0.0264
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0173 0.0681
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0256 0.1009
Schistosoma mansoni Smad4 0.0016 0.004 0.008
Loa Loa (eye worm) hypothetical protein 0.0057 0.0348 0.1162
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.004 0.0506
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0078 0.015
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0112 0.0753 0.9952
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0181 0.0599
Loa Loa (eye worm) hypothetical protein 0.0048 0.0283 0.0942
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0141 0.0278
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0071 0.0452 0.1962
Giardia lamblia Lysyl-tRNA synthetase 0.0071 0.0452 0.1759
Loa Loa (eye worm) latrophilin receptor protein 2 0.0111 0.0749 0.2506
Loa Loa (eye worm) hypothetical protein 0.0112 0.0756 0.2529
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0069 0.0131
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0515 0.3759 0.5668
Trypanosoma cruzi sugar transporter, putative 0.0045 0.0256 0.3368
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0134 0.026
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.0756 0.1486
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0014 0.0024 0.0294
Leishmania major DNA polymerase kappa, putative 0.002 0.0069 0.0883
Echinococcus granulosus voltage dependent calcium channel 0.0014 0.0024 0.0044
Brugia malayi intermediate filament protein 0.0058 0.0356 0.1405
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0002 0.0004
Trichomonas vaginalis chaperonin, putative 0.0024 0.0104 0.0444
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.0756 0.1374
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0002 0.0004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0069 0.0223
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.0104 0.0398
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0883
Trichomonas vaginalis sugar transporter, putative 0.0099 0.0659 0.2861
Toxoplasma gondii glycyl-tRNA synthetase 0.0018 0.0056 0.0081
Schistosoma mansoni lysyl-tRNA synthetase 0.0071 0.0452 0.0891
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0024 0.0044
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0141 0.0274
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0153 0.1061 0.2086
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0104 0.0205
Trichomonas vaginalis glucose transporter, putative 0.0099 0.0659 0.2861
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0025 0.0107 0.1392
Mycobacterium ulcerans beta-lactamase 0.0112 0.0756 0.7479
Echinococcus multilocularis calpain 7 (C02 family) 0.0025 0.0107 0.0207
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0256 0.1107
Schistosoma mansoni smad1 5 8 and 0.0016 0.004 0.008
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0024 0.0044
Brugia malayi Cyclic-nucleotide gated cation channel 0.0014 0.0024 0.0095
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0024 0.0033
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0049 0.0285 0.0558
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0094 0.04
Schistosoma mansoni smad1 5 8 and 0.0016 0.004 0.008
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.0504 0.0757
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.0104 0.0201
Toxoplasma gondii anticodon binding domain-containing protein 0.0011 0.0002 0.0001
Plasmodium vivax glycine--tRNA ligase, putative 0.0018 0.0056 0.0054
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0014 0.0024 0.0044
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0173 0.0681
Trypanosoma brucei calpain-like protein, putative 0.0025 0.0107 0.1392
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0045 0.0256 0.0504
Plasmodium vivax CDK-related protein kinase 6, putative 0.1353 1 1
Onchocerca volvulus Putative transporter 0.0045 0.0256 0.1393
Leishmania major kinesin, putative 0.0017 0.0051 0.0655
Schistosoma mansoni transient receptor potential channel 0.0411 0.2983 0.5877
Trypanosoma cruzi hexose transporter, putative 0.0099 0.0659 0.8706
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0011 0.0002 0.0001
Loa Loa (eye worm) major facilitator superfamily transporter 0.0045 0.0256 0.0852
Giardia lamblia Prolyl-tRNA synthetase 0.0096 0.0634 0.2471
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0098 0.0649 0.1275
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0285 0.0427
Entamoeba histolytica protein kinase, putative 0.0098 0.0649 0.2529
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0049 0.0285 0.0471
Loa Loa (eye worm) hypothetical protein 0.0014 0.0024 0.0074
Echinococcus granulosus shaker cognate 0.0014 0.0024 0.0044
Echinococcus multilocularis pyruvate kinase 0.0017 0.0051 0.0096
Loa Loa (eye worm) hypothetical protein 0.0045 0.0256 0.0852
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0024 0.0033
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0014 0.0024 0.0044
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0132 0.0256

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8.73 uM Inhibitory concentration against human plasma mu-calpain ChEMBL. 15911268
IC50 (binding) = 8.73 uM Inhibitory concentration against human plasma mu-calpain ChEMBL. 15911268
Inhibition (binding) = 21.5 % Percent inhibition of bovine cathepsin B at 0.2 uM ChEMBL. 15911268
Inhibition (binding) = 21.5 % Percent inhibition of bovine cathepsin B at 0.2 uM ChEMBL. 15911268
Inhibition (binding) = 54.2 % Percent inhibition of human liver cathepsin L at 0.2 uM ChEMBL. 15911268
Inhibition (binding) = 54.2 % Percent inhibition of human liver cathepsin L at 0.2 uM ChEMBL. 15911268
Inhibition (binding) = 55.4 % Percent inhibition of bovine cathepsin B at 2 uM ChEMBL. 15911268
Inhibition (binding) = 55.4 % Percent inhibition of bovine cathepsin B at 2 uM ChEMBL. 15911268
Inhibition (binding) = 79.9 % Percent inhibition of bovine cathepsin B at 20 uM ChEMBL. 15911268
Inhibition (binding) = 79.9 % Percent inhibition of bovine cathepsin B at 20 uM ChEMBL. 15911268
Inhibition (binding) = 87.7 % Percent inhibition of human liver cathepsin L at 2 uM ChEMBL. 15911268
Inhibition (binding) = 87.7 % Percent inhibition of human liver cathepsin L at 2 uM ChEMBL. 15911268
Inhibition (binding) = 99.1 % Percent inhibition of human liver cathepsin L at 20 uM ChEMBL. 15911268
Inhibition (binding) = 99.1 % Percent inhibition of human liver cathepsin L at 20 uM ChEMBL. 15911268

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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