Detailed information for compound 341773

Basic information

Technical information
  • TDR Targets ID: 341773
  • Name: 1-(3-bromophenyl)-2-[(2-methoxyphenyl)methyla mino]ethanol
  • MW: 336.224 | Formula: C16H18BrNO2
  • H donors: 2 H acceptors: 1 LogP: 2.8 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1CNCC(c1cccc(c1)Br)O
  • InChi: 1S/C16H18BrNO2/c1-20-16-8-3-2-5-13(16)10-18-11-15(19)12-6-4-7-14(17)9-12/h2-9,15,18-19H,10-11H2,1H3
  • InChiKey: QMYGLCYUZLYDOR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(3-bromophenyl)-2-(o-anisylamino)ethanol
  • 1-(3-bromophenyl)-2-[(2-methoxybenzyl)amino]ethanol

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Staphylococcus aureus Phenylalanyl-tRNA synthetase alpha chain Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain Get druggable targets OG5_127036 All targets in OG5_127036
Plasmodium yoelii phenylalanyl-tRNA synthetase, putative Get druggable targets OG5_127036 All targets in OG5_127036
Leishmania braziliensis phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative Get druggable targets OG5_127036 All targets in OG5_127036
Babesia bovis phenylalanyl-tRNA synthetase family protein Get druggable targets OG5_127036 All targets in OG5_127036
Theileria parva phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Leishmania mexicana phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit Get druggable targets OG5_127036 All targets in OG5_127036
Brugia malayi phenylalanyl (f) trna synthetase protein 1 Get druggable targets OG5_127036 All targets in OG5_127036
Leishmania donovani phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Candida albicans phenylalanyl-tRNA synthetase Get druggable targets OG5_127036 All targets in OG5_127036
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS Get druggable targets OG5_127036 All targets in OG5_127036
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha Get druggable targets OG5_127036 All targets in OG5_127036
Cryptosporidium parvum putative phenylalanyl-tRNA synthetase Get druggable targets OG5_127036 All targets in OG5_127036
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha Get druggable targets OG5_127036 All targets in OG5_127036
Candida albicans phenylalanyl-tRNA synthetase Get druggable targets OG5_127036 All targets in OG5_127036
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS Get druggable targets OG5_127036 All targets in OG5_127036
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative Get druggable targets OG5_127036 All targets in OG5_127036
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative Get druggable targets OG5_127036 All targets in OG5_127036
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B Get druggable targets OG5_127036 All targets in OG5_127036
Trypanosoma congolense phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127036 All targets in OG5_127036
Schistosoma japonicum ko:K01889 phenylalanyl-tRNA synthetase alpha chain [EC6.1.1.20A], putative Get druggable targets OG5_127036 All targets in OG5_127036
Plasmodium berghei phenylalanine--tRNA ligase alpha subunit, putative Get druggable targets OG5_127036 All targets in OG5_127036
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Trypanosoma brucei gambiense phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Neospora caninum hypothetical protein Get druggable targets OG5_127036 All targets in OG5_127036
Leishmania infantum phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B Get druggable targets OG5_127036 All targets in OG5_127036
Plasmodium knowlesi phenylalanine--tRNA ligase alpha subunit, putative Get druggable targets OG5_127036 All targets in OG5_127036
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha Get druggable targets OG5_127036 All targets in OG5_127036
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative Get druggable targets OG5_127036 All targets in OG5_127036
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha Get druggable targets OG5_127036 All targets in OG5_127036
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha Get druggable targets OG5_127036 All targets in OG5_127036
Cryptosporidium hominis phenylalanyl-trna synthetase-like protein Get druggable targets OG5_127036 All targets in OG5_127036
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Presenilins-associated rhomboid-like protein, mitochondrial homolog Phenylalanyl-tRNA synthetase alpha chain   352 aa 396 aa 25.0 %
Babesia bovis phenylalanine-tRNA ligase, putative Phenylalanyl-tRNA synthetase alpha chain   352 aa 359 aa 24.8 %
Theileria parva phenylalanyl-tRNA synthetase, putative Phenylalanyl-tRNA synthetase alpha chain   352 aa 315 aa 24.4 %
Candida albicans phenylalanine--tRNA ligase Phenylalanyl-tRNA synthetase alpha chain   352 aa 314 aa 27.1 %
Candida albicans phenylalanine--tRNA ligase Phenylalanyl-tRNA synthetase alpha chain   352 aa 314 aa 27.1 %
Echinococcus multilocularis phenylalanyl tRNA synthetase Phenylalanyl-tRNA synthetase alpha chain   352 aa 315 aa 28.3 %
Echinococcus granulosus phenylalanyl tRNA synthetase Phenylalanyl-tRNA synthetase alpha chain   352 aa 291 aa 29.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0669 0.0788
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0158 0.0552
Trypanosoma brucei heat shock protein, putative 0.0034 0.0316 0.0665
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0175 0.0381
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0148 0.169 0.449
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0158 0.0899
Echinococcus granulosus protocadherin 11 0.0009 0.0025 0.0029
Schistosoma mansoni ets-related 0.0011 0.0042 0.0049
Trypanosoma cruzi heat shock protein, putative 0.0014 0.0077 0.011
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0037 0.0044
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.169 0.449
Echinococcus granulosus neuroligin 0.0023 0.0189 0.0223
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0106 0.0125
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0269 0.0701
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0312 0.3669 1
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0014 0.0077 0.0295
Schistosoma mansoni hypothetical protein 0.0012 0.0052 0.0061
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0946 0.3543
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0168 0.0431
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0042 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0131 0.0154
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0012 0.0015
Echinococcus granulosus defective proboscis extension response 0.0016 0.0104 0.0123
Loa Loa (eye worm) hypothetical protein 0.0064 0.0682 0.1807
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 0.0422 0.4994 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0025 0.0048
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0151 0.0178
Echinococcus granulosus FTZ F1 alpha 0.001 0.0037 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0037 0.0081
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0016 0.0104 0.0123
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0015
Brugia malayi hypothetical protein 0.0156 0.1791 0.6753
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0042 0.0049
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0151 0.0151
Schistosoma mansoni ets-related 0.0227 0.2647 0.3115
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.1022 0.1202
Echinococcus multilocularis importin subunit beta 1 0.003 0.027 0.027
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0151 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0037 0.0093
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0687 0.0809
Echinococcus multilocularis transcription factor btf3 0.0036 0.0346 0.0346
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0225 0.0412
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0151 0.0013
Loa Loa (eye worm) cell death specification protein 2 0.0009 0.0025 0.0048
Onchocerca volvulus 0.003 0.0269 0.138
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0151 0.0827
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0145 0.0171
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0212 0.025
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0092 0.1022 0.263
Schistosoma mansoni bromodomain containing protein 0.0008 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0189 0.0488
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0106 0.0106
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0151 0.0207
Schistosoma mansoni microtubule-associated protein tau 0.0712 0.8497 1
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0346 0.0852
Loa Loa (eye worm) hypothetical protein 0.0023 0.0189 0.0488
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0189 0.009
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 0.0422 0.4994 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0158 0.0552
Schistosoma mansoni endoplasmin 0.0034 0.0316 0.0371
Schistosoma mansoni ran 0.0022 0.0175 0.0206
Brugia malayi Ets-domain containing protein 0.0075 0.0812 0.3036
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.0088 0.0977 1
Echinococcus granulosus neuropeptide s receptor 0.048 0.5693 0.6701
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0081
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0225 0.1961
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0026 0.022 0.0259
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0202 0.1799
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0145 0.0504
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0094
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Trichomonas vaginalis ran, putative 0.0022 0.0175 0.1092
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0037 0.0044
Echinococcus multilocularis zinc finger protein 0.0024 0.0197 0.0197
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0151 0.0177
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0145 0.1197
Entamoeba histolytica hypothetical protein 0.0037 0.0359 0.0793
Echinococcus multilocularis smad 0.0008 0.0012 0.0012
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0026 0.022 0.0788
Toxoplasma gondii hypothetical protein 0.005 0.0517 0.5134
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0037 0.0044
Echinococcus granulosus acetylcholinesterase 0.0136 0.1556 0.1831
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.0316 0.0767
Schistosoma mansoni zinc finger protein 0.0016 0.0102 0.012
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0037 0.0044
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0189 0.0223
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.008
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0189 0.0189
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0145 0.1152
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0189 0.0189
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0106 0.0082
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0158 0.0186
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0026 0.022 0.022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0037 0.0093
Brugia malayi Cell death specification protein 2 0.0009 0.0025 0.0047
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0037 0.0044
Schistosoma mansoni hypothetical protein 0.0175 0.2019 0.2377
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0235 0.05
Echinococcus multilocularis BRK domain containing protein 0.0012 0.0056 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0037 0.0044
Schistosoma mansoni DNA helicase recq1 0.002 0.0158 0.0186
Brugia malayi Ets-domain containing protein 0.0075 0.0812 0.3036
Echinococcus granulosus ccaat enhancer binding protein delta 0.0009 0.0025 0.0029
Brugia malayi jmjC domain containing protein 0.0016 0.0106 0.0357
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0042 0.0049
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0106 0.0125
Plasmodium vivax JmjC domain containing protein 0.0016 0.0106 0.0786
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0235 0.2149
Trypanosoma brucei heat shock protein, putative 0.0034 0.0316 0.0665
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0643 0.0757
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0175 0.0618
Trypanosoma brucei heat shock protein, putative 0.0034 0.0316 0.0665
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0316 0.2652
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0106 0.0125
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0153 0.0392
Leishmania major basic transcription factor 3a, putative 0.0036 0.0346 0.075
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0202 0.0349
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0571 0.6797 0.8
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0158 0.133
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0346 0.3324
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0014 0.0077 0.0077
Loa Loa (eye worm) BRM protein 0.0044 0.0445 0.1173
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0158 0.0333
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0346 0.0909
Loa Loa (eye worm) hypothetical protein 0.0073 0.0791 0.21
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0123 0.0145
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0106 0.0106
Entamoeba histolytica hypothetical protein 0.0024 0.0202 0.0421
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0009 0.0025 0.0029
Plasmodium falciparum flap endonuclease 1 0.0027 0.0235 0.2072
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0233 0.1737
Brugia malayi jmjC domain containing protein 0.0061 0.0643 0.2394
Brugia malayi hypothetical protein 0.0009 0.0025 0.0047
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0316 0.0691
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0316 0.0665
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0022 0.004
Schistosoma mansoni cpg binding protein 0.0033 0.0313 0.0368
Schistosoma mansoni ets 0.0011 0.0042 0.0049
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0158 0.0158
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0014 0.0077 0.0124
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Echinococcus multilocularis carboxylesterase 5A 0.0136 0.1556 0.1556
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0015
Plasmodium vivax endoplasmin, putative 0.0034 0.0316 0.3
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0016 0.0104 0.0123
Echinococcus granulosus acetylcholinesterase 0.0136 0.1556 0.1831
Schistosoma mansoni heat shock protein 0.0014 0.0077 0.0091
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.044 0.1109
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0175 0.1515
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0026 0.022 0.1588
Schistosoma mansoni ap endonuclease 0.0019 0.0145 0.0171
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.0088 0.0977 0.0977
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0189 0.009
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0946 0.0946
Brugia malayi Ets-domain containing protein 0.0011 0.0042 0.0112
Brugia malayi nuclear receptor NHR-88 0.001 0.0037 0.0093
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0092 0.1022 0.2711
Brugia malayi Hsp90 protein 0.0014 0.0077 0.0245
Giardia lamblia Heat shock protein HSP 90-alpha 0.0027 0.0233 0.0495
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0042 0.0042
Leishmania major importin beta-1 subunit, putative 0.0024 0.0202 0.0349
Schistosoma mansoni cpg binding protein 0.0033 0.0313 0.0368
Brugia malayi Fli-1 protein 0.0227 0.2647 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Loa Loa (eye worm) hypothetical protein 0.0156 0.1791 0.4778
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0151 0.0207
Echinococcus granulosus Immunoglobulin 0.0016 0.0104 0.0123
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0233 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0235 0.1759
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0026 0.022 0.1588
Echinococcus granulosus bloom syndrome protein 0.002 0.0158 0.0186
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0027 0.0233 0.0182
Brugia malayi PHD-finger family protein 0.0029 0.0264 0.0954
Brugia malayi Fibronectin type III domain containing protein 0.0016 0.0104 0.0348
Mycobacterium ulcerans hypothetical protein 0.0164 0.189 0.3599
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0012 0.0015
Echinococcus granulosus Chromo domain 0.0012 0.0056 0.0066
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0346 0.3324
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0151 0.0013
Onchocerca volvulus 0.0023 0.0189 0.093
Schistosoma mansoni ran 0.0022 0.0175 0.0206
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0037 0.0093
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0555 0.1427
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0037 0.0037
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0011 0.0041 0.0097
Brugia malayi hypothetical protein 0.0037 0.0359 0.1315
Schistosoma mansoni thyroid hormone receptor 0.001 0.0037 0.0044
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0145 0.0759
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0175 0.0381
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0145 0.0286
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0131 0.0154
Brugia malayi Cell death specification protein 2 0.0009 0.0025 0.0047
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.0088 0.0977 0.2506
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0122 0.0415
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0037 0.0093
Loa Loa (eye worm) acetylcholinesterase 1 0.0136 0.1556 0.4147
Brugia malayi hypothetical protein 0.0009 0.0025 0.0047
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0318 0.3741 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0175 0.0451
Leishmania major hypothetical protein, conserved 0.0026 0.0225 0.0412
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0159 0.0915
Leishmania major DNA polymerase kappa, putative 0.002 0.0151 0.0207
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0037 0.0044
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0106 0.0191
Echinococcus multilocularis acetylcholinesterase 0.0136 0.1556 0.1556
Echinococcus granulosus cpg binding protein 0.0033 0.0313 0.0368
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0009 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0023 0.0189 0.0488
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0235 0.0235
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.027 0.2517
Loa Loa (eye worm) hypothetical protein 0.0018 0.0131 0.0333
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0037 0.0093
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0037 0.0069
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0042 0.0112
Leishmania major hypothetical protein, conserved 0.0016 0.0102 0.0069
Loa Loa (eye worm) hypothetical protein 0.0136 0.1556 0.4147
Schistosoma mansoni gabp alpha 0.0075 0.0812 0.0956
Loa Loa (eye worm) hypothetical protein 0.0092 0.1016 0.2702
Echinococcus multilocularis cpg binding protein 0.0033 0.0313 0.0313
Echinococcus granulosus zinc finger protein 0.0024 0.0197 0.0232
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0092 0.1022 0.2711
Echinococcus multilocularis transcriptional factor nfil3:e4bp4 0.0009 0.0025 0.0025
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0151 0.0013
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.0346 0.0763
Echinococcus multilocularis protocadherin 11 0.0009 0.0025 0.0025
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0212 0.0212
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0092 0.1022 0.263
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0094
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0235 0.2149
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0189 0.0223
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0235 0.05
Schistosoma mansoni bromodomain containing protein 0.0069 0.0741 0.0872
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0081
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0037 0.0051
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0312 0.3669 1
Schistosoma mansoni hypothetical protein 0.0318 0.3741 0.4403
Plasmodium falciparum endoplasmin, putative 0.0021 0.0159 0.1261
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.189 0.3599
Brugia malayi steroid hormone receptor 0.001 0.0037 0.0093
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0158 0.0899
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0042 0.0094
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0202 0.1391
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0081
Echinococcus multilocularis BRK domain containing protein 0.0012 0.0056 0.0056
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0316 0.0767
Echinococcus multilocularis heat shock protein 90 0.0027 0.0233 0.0233
Echinococcus granulosus heat shock protein 90 0.0027 0.0233 0.0275
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0946 0.1113
Brugia malayi Protein kinase domain containing protein 0.0092 0.1022 0.3831
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Entamoeba histolytica Ran family GTPase 0.0022 0.0175 0.0357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0037 0.0081
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0106 0.0125
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0052 0.0061
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.027 0.0538
Loa Loa (eye worm) hypothetical protein 0.0023 0.0189 0.0488
Toxoplasma gondii Hsp90 domain-containing protein 0.0014 0.0077 0.0474
Echinococcus granulosus global transcription activator snf2l2 0.0072 0.0776 0.0914
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0687 0.0809
Entamoeba histolytica hypothetical protein 0.0102 0.1142 0.2652
Echinococcus granulosus muscleblind protein 0.0154 0.177 0.2083
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0225 0.0517
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Echinococcus multilocularis bloom syndrome protein 0.002 0.0158 0.0158
Echinococcus multilocularis BRK domain containing protein 0.0012 0.0056 0.0056
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0151 0.0207
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.064 0.643
Trypanosoma cruzi ISWI complex protein 0.0016 0.0102 0.0178
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0022 0.0026
Loa Loa (eye worm) hypothetical protein 0.0048 0.0484 0.1278
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Brugia malayi beta-NAC-like protein 0.0036 0.0346 0.1267
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.0088 0.0977 0.2261
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0042 0.0094
Plasmodium vivax DEAD/DEAH helicase, putative 0.0011 0.0041 0.0097
Schistosoma mansoni hypothetical protein 0.0011 0.0042 0.0049
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha 0.0422 0.4994 1
Echinococcus multilocularis Chromo domain 0.0012 0.0056 0.0056
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0158 0.0552
Schistosoma mansoni Smad4 0.0008 0.0012 0.0015
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0316 0.0665
Loa Loa (eye worm) hypothetical protein 0.0023 0.0189 0.0488
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0037 0.0044
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0042 0.0049
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0151 0.0315
Loa Loa (eye worm) hypothetical protein 0.0023 0.0189 0.0488
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0037 0.0037
Loa Loa (eye worm) helicase DNA-binding protein 0.0012 0.0056 0.0131
Schistosoma mansoni par domain protein 0.0009 0.0025 0.0029
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0225 0.2039
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0422 0.4994 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0106 0.0266
Giardia lamblia DINP protein human, muc B family 0.002 0.0151 0.03
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0346 0.075
Trypanosoma brucei heat shock protein, putative 0.0034 0.0316 0.0665
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0037 0.0043
Schistosoma mansoni gliotactin 0.0023 0.0189 0.0223
Echinococcus multilocularis neuropeptide receptor A26 0.048 0.5693 0.5693
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0225 0.1961
Trypanosoma brucei heat shock protein, putative 0.0034 0.0316 0.0665
Echinococcus multilocularis ets variant gene 4 0.0011 0.0042 0.0042
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0106 0.0695
Brugia malayi BRM protein 0.0072 0.0776 0.29
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0092 0.1022 0.2717
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0037 0.0044
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0151 0.0207
Loa Loa (eye worm) hypothetical protein 0.0009 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0009 0.0025 0.0048
Echinococcus multilocularis protein C ets 2 0.0011 0.0042 0.0042
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0037 0.0044
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0106 0.0125
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0081
Schistosoma mansoni thyrotroph embryonic factor related 0.0009 0.0025 0.0029
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0014 0.0077 0.0091
Echinococcus granulosus dual specificity 0.0092 0.1022 0.1202
Brugia malayi hypothetical protein 0.0026 0.0225 0.0806
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0012 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Schistosoma mansoni ap endonuclease 0.0019 0.0145 0.0171
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0151 0.0151
Echinococcus multilocularis neuroligin 0.0023 0.0189 0.0189
Treponema pallidum heat shock protein 90 0.0027 0.0233 0.2088
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0088 0.0977 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0081
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0189 0.0223
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0037 0.0093
Brugia malayi Cell death specification protein 2 0.0009 0.0025 0.0047
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0015 0.0093 0.0643
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0037 0.0069
Echinococcus granulosus phd:f box containing protein 0.0016 0.0106 0.0125
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0643 0.0643
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0687 0.1822
Trypanosoma brucei ISWI complex protein 0.0016 0.0102 0.0069
Echinococcus granulosus protein C ets 2 0.0011 0.0042 0.0049
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0158 0.0225
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0026 0.022 0.057
Brugia malayi Bromodomain containing protein 0.0041 0.041 0.1509
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0202 0.1391
Plasmodium falciparum heat shock protein 90, putative 0.0014 0.0077 0.0381
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0056 0.0165
Schistosoma mansoni hypothetical protein 0.0009 0.0025 0.0029
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0151 0.0527
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Entamoeba histolytica hypothetical protein 0.0037 0.0359 0.0793
Schistosoma mansoni thyroid hormone receptor 0.001 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0106 0.0125
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0202 0.1758
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0037 0.0093
Loa Loa (eye worm) hypothetical protein 0.0026 0.0225 0.0584
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0145 0.0286
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0643 0.0643
Echinococcus multilocularis microtubule associated protein 2 0.0712 0.8497 0.8497
Brugia malayi Muscleblind-like protein 0.0154 0.177 0.6671
Schistosoma mansoni zinc finger protein 0.0024 0.0197 0.0232
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.1397 0.3722
Schistosoma mansoni hypothetical protein 0.0009 0.0025 0.0029
Loa Loa (eye worm) BRM protein 0.0038 0.0373 0.098
Brugia malayi Bromodomain containing protein 0.0081 0.0887 0.3319
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.0088 0.0977 1
Plasmodium falciparum importin beta, putative 0.003 0.027 0.2444
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0037 0.0044
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.027 0.0538
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0812 0.2157
Echinococcus multilocularis muscleblind protein 1 0.0154 0.177 0.177
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0016 0.0104 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0037 0.0093
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0145 0.111
Onchocerca volvulus 0.0156 0.1791 1
Onchocerca volvulus 0.0023 0.0189 0.093
Loa Loa (eye worm) bZIP transcription factor family protein 0.0009 0.0025 0.0048
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0202 0.0117
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0316 0.0691
Echinococcus granulosus neuropeptide receptor A26 0.048 0.5693 0.6701
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0151 0.0315
Brugia malayi jmjC domain containing protein 0.0016 0.0106 0.0357
Entamoeba histolytica protein kinase domain containing protein 0.0092 0.1022 0.2367
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0012 0.0015
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0233 0.0541
Echinococcus multilocularis global transcription activator snf2l2 0.0072 0.0776 0.0776
Brugia malayi hypothetical protein 0.0023 0.0189 0.0671
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0037 0.0051
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0158 0.0316
Echinococcus granulosus heat shock protein 90 0.0034 0.0316 0.0371
Plasmodium falciparum phenylalanine--tRNA ligase 0.0026 0.022 0.1909
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.0316 0.0665
Echinococcus granulosus endoplasmin 0.0027 0.0233 0.0275
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0026 0.022 0.0259
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0812 0.0812
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0151 0.0178
Echinococcus multilocularis heat shock protein 90 0.0034 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0011 0.0042 0.0049
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0175 0.1431
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0026 0.022 0.0259
Trichomonas vaginalis lymphoid specific helicase, putative 0.0015 0.0093 0.0177
Echinococcus multilocularis roundabout 2 0.0016 0.0104 0.0104
Onchocerca volvulus 0.001 0.0037 0.0069
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0037 0.0037
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0037 0.0044
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0151 0.0387
Echinococcus multilocularis snurportin 1 0.0318 0.3741 0.3741
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0026 0.022 0.1987
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0151 0.0178
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0148 0.169 0.455
Loa Loa (eye worm) hypothetical protein 0.0009 0.0025 0.0048
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0158 0.0158
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0175 0.0175
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0037 0.0081
Toxoplasma gondii exonuclease III APE 0.0019 0.0145 0.1197
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0316 0.0767
Entamoeba histolytica recQ family DNA helicase 0.001 0.0037 0.0029
Leishmania major hypothetical protein, conserved 0.0016 0.0106 0.0082
Trypanosoma cruzi ISWI complex protein 0.0016 0.0102 0.0178
Echinococcus granulosus protocadherin 11 0.0009 0.0025 0.0029
Loa Loa (eye worm) hypothetical protein 0.0092 0.1016 0.2702
Schistosoma mansoni heat shock protein 0.0034 0.0316 0.0371
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0145 0.019
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0202 0.0349
Schistosoma mansoni transcriptional factor nfil3/e4bp4 0.0009 0.0025 0.0029
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0145 0.037
Echinococcus granulosus dna polymerase kappa 0.002 0.0151 0.0178
Loa Loa (eye worm) hypothetical protein 0.002 0.0151 0.0387
Echinococcus multilocularis muscleblind protein 0.0154 0.177 0.177
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0016 0.0104 0.0123
Schistosoma mansoni transcription factor btf3 0.0036 0.0346 0.0407
Leishmania major mitochondrial DNA polymerase beta 0.0312 0.3669 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0037 0.0044
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0189 0.1246
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0151 0.0827
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0042 0.0049
Loa Loa (eye worm) hypothetical protein 0.0009 0.0025 0.0048
Entamoeba histolytica hypothetical protein 0.0036 0.0346 0.0763
Brugia malayi Importin beta-1 subunit 0.003 0.027 0.0978
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0233 0.0182
Echinococcus multilocularis heat shock protein 0.0034 0.0316 0.0316
Echinococcus multilocularis Immunoglobulin 0.0016 0.0104 0.0104
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0189 0.0223
Schistosoma mansoni DNA polymerase eta 0.002 0.0151 0.0178
Brugia malayi nuclear hormone receptor 0.001 0.0037 0.0093
Schistosoma mansoni hypothetical protein 0.0016 0.01 0.0118
Brugia malayi Hepatic leukemia factor 0.0009 0.0025 0.0047
Brugia malayi RNA, U transporter 1 0.0085 0.0931 0.3489
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0037 0.0044
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0202 0.1719
Brugia malayi Carboxylesterase family protein 0.0023 0.0189 0.0671
Schistosoma mansoni nuclear hormone receptor 0.001 0.0037 0.0044
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0037 0.0093
Loa Loa (eye worm) hypothetical protein 0.0154 0.177 0.4721
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.0088 0.0977 1
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0346 0.3258
Trypanosoma brucei heat shock protein, putative 0.0034 0.0316 0.0665
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0015
Loa Loa (eye worm) hypothetical protein 0.0088 0.0977 0.2598
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0359 0.0422
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0346 0.0852
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0233 0.1737
Plasmodium falciparum phenylalanine--tRNA ligase 0.0026 0.022 0.1909
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0145 0.019
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0151 0.03
Trypanosoma brucei heat shock protein, putative 0.0034 0.0316 0.0665
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0359 0.4236 1
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.015 0.0311
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0106 0.0266
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0037 0.0037
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0032 0.0038
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0235 0.0611
Echinococcus multilocularis geminin 0.0175 0.2019 0.2019
Loa Loa (eye worm) carboxylesterase 0.0023 0.0189 0.0488
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0104 0.0348
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0027 0.0233 0.0182
Schistosoma mansoni flap endonuclease-1 0.0024 0.0204 0.024
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0037 0.0044
Echinococcus multilocularis endoplasmin 0.0027 0.0233 0.0233
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0212 0.025
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0022 0.0022
Trypanosoma brucei unspecified product 0.002 0.0151 0.0207
Toxoplasma gondii heat shock protein HSP90 0.0034 0.0316 0.3
Brugia malayi MH2 domain containing protein 0.0123 0.1397 0.5255
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0017 0.0122 0.0307
Schistosoma mansoni hypothetical protein 0.0012 0.0056 0.0066
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0233 0.0435
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.0088 0.0977 0.3662
Brugia malayi jmjC domain containing protein 0.0016 0.0106 0.0357
Loa Loa (eye worm) Smad1 0.0008 0.0012 0.0015
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0151 0.0315
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0159 0.0915
Echinococcus multilocularis dna polymerase kappa 0.002 0.0151 0.0151
Echinococcus granulosus microtubule associated protein 2 0.0712 0.8497 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0037 0.0093
Loa Loa (eye worm) hypothetical protein 0.004 0.0389 0.1022
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0042 0.0042
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0696 0.082
Brugia malayi hypothetical protein 0.0016 0.0104 0.0348
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0225 0.2039
Onchocerca volvulus 0.0086 0.0946 0.5213
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0158 0.0186
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0012 0.0015
Plasmodium vivax heat shock protein 90, putative 0.0014 0.0077 0.0474
Schistosoma mansoni hypothetical protein 0.0297 0.3496 0.4114
Echinococcus multilocularis dna polymerase eta 0.002 0.0151 0.0151
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.0063 0.0668 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0123 0.0145
Brugia malayi hypothetical protein 0.0017 0.0114 0.0384
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.044 0.1109
Brugia malayi transcription factor E74 isoform 0.0011 0.0042 0.0112
Loa Loa (eye worm) hypothetical protein 0.0016 0.0106 0.0266
Echinococcus multilocularis neuroglian 0.0016 0.0104 0.0104
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0145 0.0298
Brugia malayi Carboxylesterase family protein 0.0136 0.1556 0.5858
Loa Loa (eye worm) hypothetical protein 0.0086 0.0946 0.2514
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0151 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0346 0.2992
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0102 0.1142 0.2652
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0037 0.0081
Echinococcus granulosus dna polymerase eta 0.002 0.0151 0.0178
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0225 0.0517
Loa Loa (eye worm) heat shock protein 90 0.0034 0.0316 0.0827
Echinococcus multilocularis dual specificity 0.0092 0.1022 0.1022
Schistosoma mansoni heat shock protein 0.0034 0.0316 0.0371
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0037 0.0081
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.0316 0.3
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.0088 0.0977 0.2261
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0026 0.022 0.1987
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0136 0.1556 0.1831
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0175 0.0357
Plasmodium falciparum heat shock protein 90 0.0034 0.0316 0.2931
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0037 0.0093
Onchocerca volvulus 0.0023 0.0189 0.093
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0687 0.0809
Echinococcus granulosus flap endonuclease 1 0.0027 0.0235 0.0277
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0316 0.0767
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0812 0.0956
Echinococcus granulosus transcription factor btf3 0.0036 0.0346 0.0407
Schistosoma mansoni endoplasmin 0.0034 0.0316 0.0371
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0145 0.0298
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0158 0.0225
Trypanosoma brucei heat shock protein, putative 0.0034 0.0316 0.0665
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.044 0.1109
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.0088 0.0977 0.2506
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0131 0.0154
Loa Loa (eye worm) heat shock protein 75 0.0014 0.0077 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0346 0.2992
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0202 0.0117
Echinococcus granulosus X box binding protein 1 0.0297 0.3496 0.4114
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.044 0.101
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0643 0.0757
Brugia malayi bZIP transcription factor family protein 0.0009 0.0025 0.0047
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.0088 0.0977 0.2589
Loa Loa (eye worm) hypothetical protein 0.0016 0.0106 0.0266
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0189 0.009
Echinococcus multilocularis BRK domain containing protein 0.0012 0.0056 0.0056
Brugia malayi jmjC domain containing protein 0.0064 0.0687 0.2561
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0037 0.0069
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0233 0.0541
Echinococcus granulosus Smad4 0.0008 0.0012 0.0015
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0042 0.0094
Echinococcus granulosus roundabout 2 0.0016 0.0104 0.0123
Loa Loa (eye worm) RecQ helicase 0.002 0.0158 0.0404
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0151 0.0315
Loa Loa (eye worm) hypothetical protein 0.0023 0.0189 0.0488
Entamoeba histolytica recQ family helicase, putative 0.001 0.0032 0.0017
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0012 0.0015
Brugia malayi heat shock protein 90 0.0034 0.0316 0.1151
Schistosoma mansoni cpg binding protein 0.003 0.0269 0.0316
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0123 0.0123
Brugia malayi hypothetical protein 0.0009 0.0025 0.0047
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0189 0.0189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0037 0.0081
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.0316 0.0691
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0037 0.0044
Echinococcus granulosus importin subunit beta 1 0.003 0.027 0.0318
Echinococcus granulosus smad 0.0008 0.0012 0.0015
Schistosoma mansoni hypothetical protein 0.0175 0.2019 0.2377
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0131 0.0131
Leishmania major DNA polymerase eta, putative 0.002 0.0151 0.0207
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0189 0.0223
Schistosoma mansoni elf1 0.0011 0.0042 0.0049
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.1397 0.3722
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0202 0.0117
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0037 0.0037
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0037 0.0037
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0175 0.1515
Schistosoma mansoni hypothetical protein 0.0016 0.0102 0.012
Schistosoma mansoni nephrin 0.0016 0.0104 0.0123
Loa Loa (eye worm) hypothetical protein 0.003 0.027 0.0704
Brugia malayi Carboxylesterase family protein 0.0023 0.0189 0.0671
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0027 0.0233 0.0667
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0037 0.0093
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0042 0.0042
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0202 0.1391
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0316 0.0767
Loa Loa (eye worm) hypothetical protein 0.0136 0.1556 0.4147
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0037 0.0093
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0106 0.0125
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0145 0.0145
Schistosoma mansoni hypothetical protein 0.0037 0.0359 0.0422
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0696 0.0696
Echinococcus multilocularis BRK domain containing protein 0.0012 0.0056 0.0056
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0175 0.0206
Giardia lamblia Grp94/Hsp90 0.0027 0.0233 0.0495
Schistosoma mansoni vesicular amine transporter 0.0016 0.0104 0.0123
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0081
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0189 0.0223
Echinococcus multilocularis neuropeptide s receptor 0.048 0.5693 0.5693
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0106 0.0266
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0158 0.0899
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0158 0.1245
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0158 0.133
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0106 0.0106
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0175 0.0274
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0037 0.0081
Echinococcus granulosus transcriptional factor nfil3:e4bp4 0.0009 0.0025 0.0029
Schistosoma mansoni DNA helicase recq5 0.002 0.0158 0.0186
Schistosoma mansoni coup transcription factor 0.001 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Echinococcus multilocularis chromodomain helicase DNA binding protein 7 0.0012 0.0056 0.0056
Echinococcus multilocularis acetylcholinesterase 0.0136 0.1556 0.1556
Loa Loa (eye worm) hypothetical protein 0.002 0.0158 0.0404
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0202 0.0117
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0106 0.0786
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Echinococcus granulosus heat shock protein 0.0034 0.0316 0.0371
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0037 0.0093
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0088 0.0977 0.115
Echinococcus granulosus twitchin 0.0016 0.011 0.0129
Loa Loa (eye worm) carboxylesterase 0.0023 0.0189 0.0488
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0042 0.0042
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0359 0.0359
Entamoeba histolytica recQ family helicase, putative 0.002 0.0158 0.0316
Echinococcus multilocularis BRK domain 0.0012 0.0056 0.0056
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0042 0.0094
Entamoeba histolytica hypothetical protein 0.0092 0.1022 0.2367
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0151 0.0315
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Plasmodium vivax heat shock protein, putative 0.0014 0.0077 0.0474
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0042 0.0042
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0151 0.0527
Brugia malayi Endoplasmin precursor 0.0034 0.0316 0.1151
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.0088 0.0977 0.115
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Echinococcus multilocularis ccaat enhancer binding protein delta ccaat enhancer binding protein beta 0.0009 0.0025 0.0025
Loa Loa (eye worm) fli-1 protein 0.0227 0.2647 0.7069
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0189 0.1246
Echinococcus multilocularis protocadherin 11 0.0009 0.0025 0.0025
Plasmodium falciparum heat shock protein 90, putative 0.0014 0.0077 0.0381
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.008
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0009 0.0025 0.0025
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0037 0.0044
Loa Loa (eye worm) hypothetical protein 0.0044 0.044 0.116
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0009 0.0025 0.0025
Entamoeba histolytica protein kinase, putative 0.0092 0.1022 0.2367
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0946 0.1113
Brugia malayi Carboxylesterase family protein 0.0023 0.0189 0.0671
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Brugia malayi Flap endonuclease-1 0.0027 0.0235 0.0846
Schistosoma mansoni cell adhesion molecule 0.0016 0.0104 0.0123
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0358 0.0358
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0123 0.0145
Brugia malayi Carboxylesterase family protein 0.0023 0.0189 0.0671
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.026
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0346 0.2992
Loa Loa (eye worm) hypothetical protein 0.0009 0.0025 0.0048
Schistosoma mansoni importin beta-1 0.003 0.027 0.0318
Schistosoma mansoni hypothetical protein 0.0021 0.0168 0.0198
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0012 0.0012
Echinococcus granulosus neuroglian 0.0016 0.0104 0.0123
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Echinococcus multilocularis Immunoglobulin 0.0016 0.0104 0.0104
Echinococcus granulosus snurportin 1 0.0318 0.3741 0.4403
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0158 0.0404
Giardia lamblia DNA repair protein RAD52 0.0359 0.4236 1
Schistosoma mansoni acetylcholinesterase 0.0023 0.0189 0.0223
Brugia malayi jmjC domain containing protein 0.0016 0.0106 0.0357
Plasmodium vivax importin-beta 2, putative 0.003 0.027 0.2517
Schistosoma mansoni smad 0.0008 0.0012 0.0015
Echinococcus granulosus BRK domain containing protein 0.0012 0.0056 0.0066
Entamoeba histolytica hypothetical protein 0.0037 0.0359 0.0793
Echinococcus multilocularis X box binding protein 1 0.0297 0.3496 0.3496
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0044 0.012
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0037 0.0093
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0037 0.0037
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0202 0.0455
Echinococcus multilocularis BRK domain containing protein 0.0012 0.0056 0.0056
Onchocerca volvulus 0.0023 0.0189 0.093
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0106 0.0106
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0235 0.0546
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0202 0.1799
Loa Loa (eye worm) carboxylesterase 0.0136 0.1556 0.4147
Entamoeba histolytica hypothetical protein 0.0024 0.0202 0.0421
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0026 0.022 0.1987
Loa Loa (eye worm) hypothetical protein 0.0016 0.0106 0.0266
Brugia malayi ecdysteroid receptor 0.001 0.0037 0.0093
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0042 0.0049
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0037 0.0081
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0189 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0151 0.0207
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0312 0.3669 1
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0106 0.0125
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0042 0.0049
Echinococcus multilocularis Smad4 0.0008 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0037 0.0093
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0081
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0358 0.0422
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0009 0.0025 0.0029
Leishmania major GTP-binding protein, putative 0.0022 0.0175 0.0274
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0233 0.1737
Echinococcus granulosus geminin 0.0175 0.2019 0.2377
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0235 0.0441
Toxoplasma gondii heat shock protein 75, putative 0.0014 0.0077 0.0474
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0202 0.1799
Schistosoma mansoni helicase 0.0072 0.0776 0.0914
Onchocerca volvulus 0.0023 0.0189 0.093
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0037 0.0037
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0106 0.0786
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Leishmania major heat shock protein 83-1 0.0034 0.0316 0.0665
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0359 0.0422
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0235 0.0441
Entamoeba histolytica protein kinase, putative 0.0092 0.1022 0.2367
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0037 0.0037
Plasmodium vivax heat shock protein 86, putative 0.0034 0.0316 0.3
Loa Loa (eye worm) hypothetical protein 0.001 0.0037 0.0081
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.0088 0.0977 1
Brugia malayi CXXC zinc finger family protein 0.003 0.0269 0.0972
Loa Loa (eye worm) hypothetical protein 0.0154 0.177 0.4721
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0145 0.0759
Entamoeba histolytica hypothetical protein 0.0037 0.0359 0.0793
Brugia malayi Carboxylesterase family protein 0.0136 0.1556 0.5858
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0042 0.0049
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0158 0.1245
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0189 0.0223
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0189 0.0223
Echinococcus granulosus carboxylesterase 5A 0.0136 0.1556 0.1831
Loa Loa (eye worm) endoplasmin 0.0034 0.0316 0.0827
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0106 0.0191

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 110 nM Inhibitory concentration against Staphylococcus aureus Phenylalanyl-tRNA synthetase ChEMBL. 15837314
IC50 (binding) = 110 nM Inhibitory concentration against Staphylococcus aureus Phenylalanyl-tRNA synthetase ChEMBL. 15837314

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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