Detailed information for compound 378092

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1350.65 | Formula: C52H79N13O17S6
  • H donors: 14 H acceptors: 17 LogP: -2.63 Rotable bonds: 51
    Rule of 5 violations (Lipinski): 4
  • SMILES: SCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCCC1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)O)CS)Cc1ccccc1)CS)C)CC(=O)N)CS)CS)[C@H](CC)C)CCC(=O)O)CS
  • InChi: 1S/C52H79N13O17S6/c1-4-25(2)41(64-44(73)28(12-13-40(69)70)58-45(74)31(20-84)56-38(67)14-16-83)50(79)63-34(23-87)48(77)62-33(22-86)47(76)60-30(18-37(53)66)51(80)65-15-8-11-36(65)49(78)55-26(3)42(71)61-32(21-85)46(75)59-29(17-27-9-6-5-7-10-27)43(72)54-19-39(68)57-35(24-88)52(81)82/h5-7,9-10,25-26,28-36,41,83-88H,4,8,11-24H2,1-3H3,(H2,53,66)(H,54,72)(H,55,78)(H,56,67)(H,57,68)(H,58,74)(H,59,75)(H,60,76)(H,61,71)(H,62,77)(H,63,79)(H,64,73)(H,69,70)(H,81,82)/t25-,26+,28+,29+,30+,31+,32+,33+,34+,35+,36?,41+/m1/s1
  • InChiKey: YHSLYDSLZGFEBF-MGQHPRSCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus glutamate receptor 2 0.0059 0.0485 0.048
Schistosoma mansoni protein tyrosine kinase 0.0216 0.2171 0.2159
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0279 0.0266
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Loa Loa (eye worm) hypothetical protein 0.0111 0.1044 0.1044
Schistosoma mansoni suppressor of cytokine signaling 0.0314 0.322 0.321
Loa Loa (eye worm) hypothetical protein 0.0035 0.0232 0.0232
Onchocerca volvulus 0.0314 0.322 0.5807
Brugia malayi hypothetical protein 0.0059 0.0485 0.0472
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0578 0.0564
Entamoeba histolytica tyrosin kinase, putative 0.0216 0.2171 0.3907
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0293 0.3003 1
Plasmodium falciparum tyrosine kinase-like protein 0.0216 0.2171 0.4614
Entamoeba histolytica hypothetical protein 0.004 0.0285 0.0491
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0166 0.0166
Schistosoma mansoni carbonic anhydrase-related 0.0444 0.4621 0.4613
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine protein kinase Fyn 0.053 0.5535 0.5532
Trypanosoma brucei Flagellum attachment zone protein 20 0.0216 0.2171 0.216
Echinococcus multilocularis tyrosine protein kinase csk 0.0216 0.2171 0.2166
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0194 0.0603
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0279 0.0889
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0077 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.2171 0.2159
Brugia malayi Guanylyl cyclase protein 23 0.0275 0.28 0.279
Loa Loa (eye worm) TK/DDR protein kinase 0.0216 0.2171 0.2171
Echinococcus granulosus tyrosine protein kinase csk 0.0216 0.2171 0.2166
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0946 1 1
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0194 0.0603
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Loa Loa (eye worm) fatty acid synthase 0.0027 0.015 0.015
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0015 0.001
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0173 0.1713 0.1709
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0194 0.0415
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Brugia malayi Protein kinase domain containing protein 0.053 0.5535 0.5529
Mycobacterium ulcerans hypothetical protein 0.0078 0.0695 0.2276
Loa Loa (eye worm) hypothetical protein 0.0047 0.0357 0.0357
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0216 0.2171 0.216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0077 0.0077
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0166 0.0153
Loa Loa (eye worm) SH2 domain-containing protein 0.0314 0.322 0.322
Brugia malayi Glutamate receptor 1 precursor 0.0114 0.1084 0.1072
Echinococcus multilocularis tyrosine protein kinase shark 0.053 0.5535 0.5532
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0018 0.0053 0.0126
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Schistosoma mansoni glutamate receptor AMPA 0.0114 0.1084 0.107
Brugia malayi Tyrosine-protein kinase abl-1 0.053 0.5535 0.5529
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0578 0.0573
Brugia malayi Variant SH3 domain containing protein 0.0314 0.322 0.3211
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0279 0.0889
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0314 0.322 0.5807
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Brugia malayi Tensin 0.0314 0.322 0.3211
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0077 0.0071
Loa Loa (eye worm) TK protein kinase 0.053 0.5535 0.5535
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0072 0.0067
Trypanosoma brucei Pseudokinase, putative 0.0216 0.2171 0.216
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0077 0.0071
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0015 0.0002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0401 0.0401
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0946 1 1
Echinococcus granulosus GPCR family 2 0.0035 0.0232 0.0226
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.1107 0.1107
Echinococcus granulosus growth factor receptor bound protein 2 0.0314 0.322 0.3216
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0072 0.0059
Brugia malayi Cytochrome P450 family protein 0.0015 0.0015 0.0002
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0077 0.0063
Loa Loa (eye worm) beta-lactamase 0.0078 0.0695 0.0695
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0194 0.0603
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0015 0.0002
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0077 0.0077
Schistosoma mansoni tyrosine kinase 0.0275 0.28 0.2789
Echinococcus multilocularis epidermal growth factor receptor 0.0216 0.2171 0.2166
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.053 0.5535 0.5532
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Loa Loa (eye worm) TK/Met protein kinase 0.0216 0.2171 0.2171
Loa Loa (eye worm) SRC-1 0.053 0.5535 0.5535
Mycobacterium ulcerans glutaminase 0.0293 0.3003 0.9999
Toxoplasma gondii type I fatty acid synthase, putative 0.002 0.0068 0.0133
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Echinococcus granulosus glutamate receptor 2 0.0173 0.1713 0.1709
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Onchocerca volvulus 0.0078 0.0695 0.1235
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0279 0.0889
Echinococcus multilocularis raf serine:threonine protein kinase 0.0216 0.2171 0.2166
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Entamoeba histolytica SH2 domain containing protein 0.0314 0.322 0.5807
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0444 0.4621 0.4614
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.1107 0.1102
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Mycobacterium tuberculosis Probable thioesterase TesA 0.0023 0.0104 0.0171
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0077 0.0077
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0695 0.0683
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.003 0.0172 0.0526
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.003 0.0172 0.0526
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Echinococcus multilocularis SHC transforming protein 3 0.0314 0.322 0.3216
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0314 0.322 0.321
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Echinococcus granulosus tyrosine protein kinase csk 0.0216 0.2171 0.2166
Brugia malayi glutaminase DH11.1 0.0293 0.3003 0.2993
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0216 0.2171 0.216
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0194 0.0603
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0314 0.322 0.3216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0077
Schistosoma mansoni growth factor receptor-bound protein 0.0314 0.322 0.321
Entamoeba histolytica protein kinase, putative 0.0314 0.322 0.5807
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Schistosoma mansoni tyrosine kinase 0.053 0.5535 0.5528
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.053 0.5535 0.5532
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.1107 0.1981
Echinococcus granulosus receptor type guanylyl cyclase 0.0275 0.28 0.2796
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0026 0.0134 0.0229
Entamoeba histolytica hypothetical protein 0.0021 0.0077 0.0114
Echinococcus multilocularis tyrosine protein kinase csk 0.0216 0.2171 0.2166
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.002 0.0029
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0072 0.0197
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0077 0.0061
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Echinococcus granulosus lamin 0.0029 0.0166 0.0161
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0401 0.0395
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0015 0.0015
Brugia malayi Sex muscle abnormal protein 5 0.0314 0.322 0.3211
Echinococcus multilocularis insulin receptor 0.0216 0.2171 0.2166
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0173 0.1713 0.1709
Mycobacterium ulcerans Type I modular polyketide synthase 0.0028 0.0154 0.0464
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0077 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0216 0.2171 0.7216
Schistosoma mansoni serine/threonine RGC 0.0216 0.2171 0.2159
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0444 0.4621 0.4614
Brugia malayi Variant SH3 domain containing protein 0.0314 0.322 0.3211
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0216 0.2171 0.2159
Plasmodium falciparum protein kinase, putative 0.0216 0.2171 0.4614
Onchocerca volvulus 0.0216 0.2171 0.3907
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Schistosoma mansoni vav2 0.0314 0.322 0.321
Loa Loa (eye worm) TK/ALK protein kinase 0.0216 0.2171 0.2171
Entamoeba histolytica tyrosin kinase, putative 0.0216 0.2171 0.3907
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0015 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0027 0.0145 0.0249
Onchocerca volvulus 0.0314 0.322 0.5807
Trichomonas vaginalis protein tyrosine kinase, putative 0.0216 0.2171 0.7216
Loa Loa (eye worm) hypothetical protein 0.0029 0.0166 0.0166
Echinococcus granulosus neuropeptide s receptor 0.0514 0.5366 0.5363
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0695 0.3134
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis tyrosine protein kinase ABL1 0.053 0.5535 0.5532
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0102 0.0088
Schistosoma mansoni hypothetical protein 0.0035 0.0232 0.0217
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Onchocerca volvulus 0.0216 0.2171 0.3907
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0216 0.2171 0.3907
Schistosoma mansoni tyrosine kinase 0.053 0.5535 0.5528
Loa Loa (eye worm) cytochrome P450 0.0015 0.0015 0.0015
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0695 0.1307
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0015 0.0019
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0072 0.0197
Entamoeba histolytica hypothetical protein 0.0021 0.0077 0.0114
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0216 0.2171 0.2166
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0194 0.0327
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0077 0.0071
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0293 0.3003 0.5742
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0695 0.228
Loa Loa (eye worm) hypothetical protein 0.0339 0.3489 0.3489
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Echinococcus granulosus tyrosine protein kinase Lyn 0.053 0.5535 0.5532
Schistosoma mansoni signal transduction protein lnk-related 0.0314 0.322 0.321
Brugia malayi tRNA modification GTPase TrmE family protein 0.0314 0.322 0.3211
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0077 0.0063
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0077 0.0061
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Schistosoma mansoni glutamate receptor NMDA 0.0173 0.1713 0.1701
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0216 0.2171 0.2166
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0695 0.0681
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0114 0.1084 0.1079
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0695 0.0695
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0072 0.0002
Echinococcus multilocularis glutamate receptor 2 0.0114 0.1084 0.1079
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.2171 0.2171
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0077 0.0071
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0279 0.0591
Schistosoma mansoni growth factor receptor-bound protein 0.0314 0.322 0.321
Echinococcus granulosus tyrosine protein kinase Fps85D 0.053 0.5535 0.5532
Entamoeba histolytica hypothetical protein 0.004 0.0285 0.0491
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0077 0.0071
Onchocerca volvulus 0.0216 0.2171 0.3907
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0216 0.2171 0.2166
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0444 0.4621 0.4614
Echinococcus granulosus atrial natriuretic peptide receptor 0.0059 0.0485 0.048
Brugia malayi Raf kinase 0.0216 0.2171 0.216
Echinococcus granulosus insulin receptor 0.0216 0.2171 0.2166
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Schistosoma mansoni hypothetical protein 0.0035 0.0232 0.0217
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine protein kinase Fyn 0.053 0.5535 0.5532
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Echinococcus granulosus expressed protein 0.0401 0.4153 0.415
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.053 0.5535 0.5532
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0194 0.0406
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0232 0.0226
Schistosoma mansoni hypothetical protein 0.0216 0.2171 0.2159
Echinococcus multilocularis neuropeptide s receptor 0.0514 0.5366 0.5363
Chlamydia trachomatis glutamine binding protein 0.0293 0.3003 1
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Plasmodium vivax protein kinase, putative 0.0216 0.2171 1
Loa Loa (eye worm) hypothetical protein 0.0444 0.4621 0.4621
Echinococcus granulosus natriuretic peptide receptor 1 0.0216 0.2171 0.2166
Onchocerca volvulus 0.0029 0.0166 0.0277
Echinococcus multilocularis heat shock protein 70 0.0216 0.2171 0.2166
Schistosoma mansoni hypothetical protein 0.0114 0.1084 0.107
Brugia malayi Protein kinase domain containing protein 0.053 0.5535 0.5529
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.2171 0.2171
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0293 0.3003 1
Echinococcus multilocularis nmda type glutamate receptor 0.0059 0.0485 0.048
Echinococcus multilocularis SH2 domain containing protein 7 0.0314 0.322 0.3216
Onchocerca volvulus 0.053 0.5535 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0216 0.2171 0.216
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0279 0.0889
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Echinococcus multilocularis tyrosine protein kinase HCK 0.0216 0.2171 0.2166
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Brugia malayi SH2 domain containing protein 0.0314 0.322 0.3211
Onchocerca volvulus 0.0216 0.2171 0.3907
Loa Loa (eye worm) protein kinase domain-containing protein 0.0216 0.2171 0.2171
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0279 0.0481
Echinococcus granulosus SH2 domain containing adapter protein F 0.0314 0.322 0.3216
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0077 0.0061
Brugia malayi Protein kinase domain containing protein 0.053 0.5535 0.5529
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0216 0.2171 0.2166
Echinococcus granulosus protein tyrosine kinase 0.0216 0.2171 0.2166
Entamoeba histolytica tyrosin kinase, putative 0.0216 0.2171 0.3907
Echinococcus granulosus tyrosine protein kinase Src42A 0.0314 0.322 0.3216
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0114 0.1084 0.1079
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0216 0.2171 0.2166
Schistosoma mansoni glutamate receptor kainate 0.0114 0.1084 0.107
Loa Loa (eye worm) hypothetical protein 0.0078 0.0695 0.0695
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.2171 0.2171
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Brugia malayi phosphofructokinase 0.0117 0.1107 0.1095
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0578 0.0564
Loa Loa (eye worm) TK/CSK protein kinase 0.0216 0.2171 0.2171
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Echinococcus granulosus intermediate filament protein 0.0029 0.0166 0.0161
Trypanosoma cruzi protein kinase, putative 0.0216 0.2171 0.216
Onchocerca volvulus 0.0216 0.2171 0.3907
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0028 0.0154 0.0267
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Echinococcus granulosus tyrosine protein kinase 0.0216 0.2171 0.2166
Onchocerca volvulus 0.0216 0.2171 0.3907
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.1764 0.1753
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0026 0.0134 0.0134
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Echinococcus granulosus tyrosine protein kinase Fyn 0.053 0.5535 0.5532
Loa Loa (eye worm) carbonic anhydrase 3 0.0946 1 1
Schistosoma mansoni carbonic anhydrase 0.0444 0.4621 0.4613
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.2171 0.2159
Giardia lamblia Protein 21.1 0.0216 0.2171 1
Schistosoma mansoni carbonic anhydrase-related 0.0444 0.4621 0.4613
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0293 0.3003 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0173 0.1713 0.1709
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0077 0.0061
Schistosoma mansoni SH2A 0.0314 0.322 0.321
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Echinococcus granulosus activin receptor type 0.0216 0.2171 0.2166
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0015 0.0015
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0077 0.0071
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Entamoeba histolytica hypothetical protein 0.004 0.0285 0.0491
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0077 0.0071
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0695 0.1307
Echinococcus multilocularis carbonic anhydrase 0.0444 0.4621 0.4618
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Loa Loa (eye worm) TK/EPH protein kinase 0.0216 0.2171 0.2171
Brugia malayi latrophilin 2 splice variant baaae 0.0076 0.0668 0.0655
Echinococcus granulosus tyrosine protein kinase Btk29A 0.053 0.5535 0.5532
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Echinococcus granulosus lamin dm0 0.0029 0.0166 0.0161
Brugia malayi hypothetical protein 0.0314 0.322 0.3211
Echinococcus multilocularis tyrosine protein kinase pr2 0.0216 0.2171 0.2166
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Echinococcus granulosus activated cdc42 kinase 1 0.0216 0.2171 0.2166
Toxoplasma gondii protein kinase 0.0216 0.2171 0.469
Entamoeba histolytica serine/threonine kinase, putative 0.0216 0.2171 0.3907
Brugia malayi ephrin receptor 1 precursor 0.0216 0.2171 0.216
Schistosoma mansoni alpha glucosidase 0.0039 0.0279 0.0265
Echinococcus granulosus tyrosine protein kinase Fyn 0.053 0.5535 0.5532
Brugia malayi Cytochrome P450 family protein 0.0015 0.0015 0.0002
Entamoeba histolytica ankyrin repeat protein 0.0216 0.2171 0.3907
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0072 0.0191
Schistosoma mansoni lamin 0.0029 0.0166 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0077 0.0211
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0166 0.0166
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Echinococcus multilocularis SH2 motif 0.0314 0.322 0.3216
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0077 0.0061
Schistosoma mansoni hypothetical protein 0.0035 0.0232 0.0217
Onchocerca volvulus 0.0103 0.096 0.1714
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0194 0.0269
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0401 0.0386
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Brugia malayi hypothetical protein 0.0017 0.0041 0.0028
Loa Loa (eye worm) phosphofructokinase 0.0117 0.1107 0.1107
Echinococcus granulosus tyrosine kinase 0.053 0.5535 0.5532
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0216 0.2171 0.216
Trichomonas vaginalis conserved hypothetical protein 0.0216 0.2171 0.7216
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Onchocerca volvulus 0.0026 0.0134 0.0219
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0216 0.2171 0.2166
Leishmania major protein kinase, putative 0.0216 0.2171 0.216
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0077 0.0061
Entamoeba histolytica hypothetical protein, conserved 0.0216 0.2171 0.3907
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis tensin 0.0314 0.322 0.3216
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Mycobacterium ulcerans beta-lactamase 0.0078 0.0695 0.2276
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0059 0.0485 0.0485
Loa Loa (eye worm) RNA binding protein 0.0067 0.0578 0.0578
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0401 0.0386
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Schistosoma mansoni hypothetical protein 0.0573 0.5996 0.599
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.1107 0.3531
Echinococcus granulosus carbonic anhydrase 0.0444 0.4621 0.4618
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.1107 0.1981
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0216 0.2171 0.2166
Brugia malayi Calcitonin receptor-like protein seb-1 0.0111 0.1044 0.1032
Echinococcus multilocularis muscleblind protein 1 0.0339 0.3489 0.3485
Echinococcus multilocularis tyrosine protein kinase Src42A 0.053 0.5535 0.5532
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Mycobacterium ulcerans polyketide synthase 0.0028 0.0154 0.0464
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.1107 0.3658
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0695 0.228
Echinococcus multilocularis 0.0015 0.0015 0.001
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0314 0.322 0.5807
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Onchocerca volvulus 0.0078 0.0695 0.1235
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Onchocerca volvulus 0.0314 0.322 0.5807
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0143 0.0157
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0695 0.1307
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0216 0.2171 0.2166
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Schistosoma mansoni shc transforming protein 0.0314 0.322 0.321
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0695 0.0683
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.1107 0.1095
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0695 0.228
Entamoeba histolytica serine/threonine kinase, putative 0.0216 0.2171 0.3907
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Echinococcus multilocularis tyrosine protein kinase Abl 0.053 0.5535 0.5532
Schistosoma mansoni hypothetical protein 0.0444 0.4621 0.4613
Echinococcus granulosus neuropeptide receptor A26 0.0514 0.5366 0.5363
Brugia malayi Receptor family ligand binding region containing protein 0.0059 0.0485 0.0472
Entamoeba histolytica tyrosin kinase, putative 0.0216 0.2171 0.3907
Schistosoma mansoni hypothetical protein 0.004 0.0285 0.027
Schistosoma mansoni tensin 0.0314 0.322 0.321
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0314 0.322 0.3216
Loa Loa (eye worm) SH2 domain-containing protein 0.0314 0.322 0.322
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) glutamate receptor 0.0059 0.0485 0.0485
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0077 0.0071
Echinococcus granulosus tar DNA binding protein 0.0067 0.0578 0.0573
Loa Loa (eye worm) hypothetical protein 0.0275 0.28 0.28
Entamoeba histolytica hypothetical protein 0.0059 0.0485 0.0854
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0194 0.0603
Echinococcus granulosus N chimaerin 0.0314 0.322 0.3216
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0143 0.0564
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0077 0.0061
Echinococcus granulosus tyrosine protein kinase shark 0.053 0.5535 0.5532
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0022 0.0022
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0194 0.08
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0018 0.0053 0.0345
Echinococcus multilocularis tyrosine protein kinase csk 0.0216 0.2171 0.2166
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0077 0.0211
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0216 0.2171 0.7216
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0072 0.0059
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0114 0.1084 0.1079
Trichomonas vaginalis AGC family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0216 0.2171 0.2166
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0102 0.0294
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus granulosus signal transduction protein lnk realted 0.0314 0.322 0.3216
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Brugia malayi SH2 domain containing protein 0.0314 0.322 0.3211
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0077 0.0071
Entamoeba histolytica cysteine surface protein, putative 0.0216 0.2171 0.3907
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0232 0.0218
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Trichomonas vaginalis STE family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0216 0.2171 0.2171
Echinococcus multilocularis transfer RNA-Thr 0.0216 0.2171 0.2166
Schistosoma mansoni ap endonuclease 0.002 0.0072 0.0057
Trichomonas vaginalis TK family protein kinase 0.0216 0.2171 0.7216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Onchocerca volvulus 0.0059 0.0485 0.0854
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0279 0.0266
Brugia malayi RhoGAP domain containing protein 0.0314 0.322 0.3211
Onchocerca volvulus 0.053 0.5535 1
Schistosoma mansoni tensin-related 0.0314 0.322 0.321
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine protein kinase Srms 0.053 0.5535 0.5532
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0173 0.1713 0.1709
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0077 0.0063
Echinococcus granulosus integrin linked protein kinase 0.0216 0.2171 0.2166
Onchocerca volvulus 0.053 0.5535 1
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0015 0.0015
Schistosoma mansoni GTPase activating protein 0.0314 0.322 0.321
Leishmania major cytochrome p450-like protein 0.0015 0.0015 0.0002
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Echinococcus multilocularis carbonic anhydrase 0.0444 0.4621 0.4618
Echinococcus granulosus c src tyrosine kinase 0.053 0.5535 0.5532
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0401 0.0388
Brugia malayi hypothetical protein 0.0216 0.2171 0.216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0077
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0314 0.322 0.3211
Loa Loa (eye worm) hypothetical protein 0.0059 0.0485 0.0485
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0072 0.0059
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0077 0.0077
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0077 0.0071
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Schistosoma mansoni alpha-glucosidase 0.0153 0.1499 0.1486
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0028 0.0154 0.0267
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0314 0.322 0.3216
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0042 0.0301 0.055
Echinococcus granulosus tyrosine protein kinase Fyn 0.053 0.5535 0.5532
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0285 0.027
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0279 0.0889
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0695 0.1307
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) hypothetical protein 0.0078 0.0695 0.0695
Echinococcus granulosus tyrosine protein kinase Src64B 0.053 0.5535 0.5532
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0102 0.0294
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.1107 0.1094
Echinococcus granulosus retinal guanylyl cyclase 2 0.0216 0.2171 0.2166
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.2171 0.2171
Echinococcus multilocularis kinase suppressor of Ras 1 0.0216 0.2171 0.2166
Brugia malayi bone morphogenetic protein type 1 receptor 0.0216 0.2171 0.216
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0314 0.322 0.322
Entamoeba histolytica ankyrin repeat protein 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine kinase 0.053 0.5535 0.5532
Echinococcus multilocularis expressed protein 0.0401 0.4153 0.415
Trichomonas vaginalis conserved hypothetical protein 0.0216 0.2171 0.7216
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0216 0.2171 0.2171
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0143 0.013
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0028 0.0154 0.0267
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.1107 0.1095
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0314 0.322 0.322
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0216 0.2171 0.3907
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0314 0.322 0.321
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Onchocerca volvulus 0.053 0.5535 1
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0578 0.0565
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0042 0.0301 0.055
Echinococcus granulosus tyrosine protein kinase csk 0.0216 0.2171 0.2166
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Entamoeba histolytica hypothetical protein 0.004 0.0285 0.0491
Onchocerca volvulus Fatty acid synthase homolog 0.005 0.0393 0.0687
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0216 0.2171 0.2166
Echinococcus granulosus tyrosine protein kinase ABL1 0.053 0.5535 0.5532
Schistosoma mansoni lamin 0.0029 0.0166 0.0151
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0216 0.2171 0.2166
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0314 0.322 0.3216
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0285 0.0279
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0072 0.0106
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0695 0.0683
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0059 0.0485 0.0485
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Schistosoma mansoni glutamate receptor kainate 0.0114 0.1084 0.107
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0216 0.2171 0.7216
Loa Loa (eye worm) hypothetical protein 0.0078 0.0695 0.0695
Brugia malayi Furin-like cysteine rich region family protein 0.0216 0.2171 0.216
Toxoplasma gondii ABC1 family protein 0.0078 0.0695 0.1493
Echinococcus granulosus retinal guanylyl cyclase 2 0.0216 0.2171 0.2166
Brugia malayi Muscleblind-like protein 0.0339 0.3489 0.348
Schistosoma mansoni tyrosine kinase 0.0275 0.28 0.2789
Loa Loa (eye worm) TK/ABL protein kinase 0.053 0.5535 0.5535
Loa Loa (eye worm) RGC/RGC protein kinase 0.0275 0.28 0.28
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0232 0.0218
Brugia malayi Cytochrome P450 family protein 0.0015 0.0015 0.0002
Echinococcus multilocularis signal transduction protein lnk realted 0.0314 0.322 0.3216
Echinococcus multilocularis SH2 motif 0.0314 0.322 0.3216
Brugia malayi C-terminal src kinase protein 1 0.0216 0.2171 0.216
Onchocerca volvulus 0.0314 0.322 0.5807
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0077 0.0071
Echinococcus granulosus nmda type glutamate receptor 0.0408 0.4231 0.4228
Loa Loa (eye worm) STAT protein 0.0314 0.322 0.322
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0194 0.0603
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Echinococcus multilocularis N chimaerin 0.0314 0.322 0.3216
Schistosoma mansoni tensin 0.0314 0.322 0.321
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0016 0.0025 0.0019
Brugia malayi hypothetical protein 0.053 0.5535 0.5529
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.2171 0.2171
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0077 0.0061
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0114 0.1084 0.1079
Schistosoma mansoni intermediate filament proteins 0.0029 0.0166 0.0151
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Brugia malayi cytokine inducible SH2-containing protein 5 0.0314 0.322 0.3211
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0314 0.322 0.3216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.005 0.0035
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0015 0.0015
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0028 0.0154 0.0464
Echinococcus granulosus tensin 0.0314 0.322 0.3216
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0314 0.322 0.321
Loa Loa (eye worm) SH2 domain-containing protein 0.0314 0.322 0.322
Mycobacterium ulcerans Type I modular polyketide synthase 0.0028 0.0154 0.0464
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0216 0.2171 0.2166
Echinococcus granulosus tyrosine kinase 0.053 0.5535 0.5532
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0314 0.322 0.322
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0444 0.4621 0.4614
Toxoplasma gondii protein kinase domain-containing protein 0.0216 0.2171 0.469
Brugia malayi 6-phosphofructokinase 0.0117 0.1107 0.1095
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0053 0.0421 0.0408
Loa Loa (eye worm) TK/RYK protein kinase 0.0216 0.2171 0.2171
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0059 0.0485 0.048
Entamoeba histolytica serine/threonine kinase, putative 0.0216 0.2171 0.3907
Brugia malayi SH2 domain containing protein 0.053 0.5535 0.5529
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0695 0.1307
Echinococcus granulosus tyrosine protein kinase Src42A 0.053 0.5535 0.5532
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0695 0.2276
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0232 0.0226
Schistosoma mansoni ephrin receptor 0.0216 0.2171 0.2159
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.2171 0.2171
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Trypanosoma brucei protein kinase, putative 0.0216 0.2171 0.216
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0059 0.0485 0.0485
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0314 0.322 0.3216
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.1107 0.1102
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Echinococcus multilocularis receptor type guanylyl cyclase 0.0275 0.28 0.2796
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0216 0.2171 0.2159
Echinococcus multilocularis FL cytokine receptor 0.0216 0.2171 0.2166
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Loa Loa (eye worm) hypothetical protein 0.0339 0.3489 0.3489
Loa Loa (eye worm) RGC/RGC protein kinase 0.0275 0.28 0.28
Schistosoma mansoni tyrosine protein kinase 0.0216 0.2171 0.2159
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus granulosus expressed conserved protein 0.0314 0.322 0.3216
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) TK/EGFR protein kinase 0.0216 0.2171 0.2171
Echinococcus granulosus NCK adaptor protein 0.0314 0.322 0.3216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine protein kinase csk 0.0216 0.2171 0.2166
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0216 0.2171 0.2171
Schistosoma mansoni hypothetical protein 0.0035 0.0232 0.0217
Brugia malayi SH2 domain containing protein 0.0314 0.322 0.3211
Brugia malayi RNA binding protein 0.0067 0.0578 0.0565
Schistosoma mansoni hypothetical protein 0.0314 0.322 0.321
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0695 0.228
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0216 0.2171 0.2166
Echinococcus multilocularis integrin linked protein kinase 0.0216 0.2171 0.2166
Echinococcus granulosus metabotropic glutamate receptor 2 0.0059 0.0485 0.048
Brugia malayi Cytochrome P450 family protein 0.0015 0.0015 0.0002
Schistosoma mansoni hypothetical protein 0.0076 0.0668 0.0654
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0015 0.0002
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0194 0.0406
Schistosoma mansoni protein kinase 0.0275 0.28 0.2789
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0077 0.0071
Echinococcus granulosus tyrosine protein kinase Blk 0.053 0.5535 0.5532
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.053 0.5535 0.5532
Echinococcus granulosus geminin 0.0573 0.5996 0.5994
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0314 0.322 0.3216
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0111 0.1044 0.1032
Schistosoma mansoni tensin-related 0.0314 0.322 0.321
Mycobacterium tuberculosis Conserved protein 0.0078 0.0695 0.1307
Echinococcus multilocularis tyrosine protein kinase Src64B 0.053 0.5535 0.5532
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0027 0.0145 0.0249
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.2171 0.2159
Loa Loa (eye worm) hypothetical protein 0.053 0.5535 0.5535
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Trichomonas vaginalis conserved hypothetical protein 0.0216 0.2171 0.7216
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0077 0.0211
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.1107 0.1095
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0216 0.2171 0.3907
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Toxoplasma gondii exonuclease III APE 0.002 0.0072 0.0143
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.1107 0.3658
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0216 0.2171 0.216
Schistosoma mansoni glutaminase 0.0293 0.3003 0.2992
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0216 0.2171 0.2171
Echinococcus granulosus tyrosine protein kinase HCK 0.0216 0.2171 0.2166
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Giardia lamblia Kinase, NEK 0.0216 0.2171 1
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Brugia malayi hypothetical protein 0.0021 0.0077 0.0063
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0077 0.0061
Echinococcus granulosus muscleblind protein 0.0339 0.3489 0.3485
Loa Loa (eye worm) hypothetical protein 0.0444 0.4621 0.4621
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0314 0.322 0.3216
Leishmania major hypothetical protein, conserved 0.0027 0.0143 0.013
Echinococcus granulosus SH2 motif 0.0314 0.322 0.3216
Entamoeba histolytica serine/threonine kinase, putative 0.0216 0.2171 0.3907
Brugia malayi beta-lactamase family protein 0.0078 0.0695 0.0683
Echinococcus granulosus tyrosine protein kinase pr2 0.0216 0.2171 0.2166
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Schistosoma mansoni ephrin receptor 0.0216 0.2171 0.2159
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0216 0.2171 0.2171
Brugia malayi SH2 domain containing protein 0.0314 0.322 0.3211
Schistosoma mansoni glutamate receptor AMPA 0.0114 0.1084 0.107
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Mycobacterium tuberculosis Conserved protein 0.0078 0.0695 0.1307
Mycobacterium ulcerans polyketide synthase Pks9 0.0018 0.0053 0.0126
Echinococcus granulosus kinase suppressor of Ras 1 0.0216 0.2171 0.2166
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0134 0.0121
Schistosoma mansoni tyrosine kinase 0.053 0.5535 0.5528
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.1764 0.1764
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0015 0.0002
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0216 0.2171 0.2166
Echinococcus multilocularis carbonic anhydrase II 0.0946 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Brugia malayi Immunoglobulin I-set domain containing protein 0.0216 0.2171 0.216
Onchocerca volvulus Tyrosine kinase homolog 0.0216 0.2171 0.3907
Echinococcus multilocularis protein KINase family member (kin 25) 0.0216 0.2171 0.2166
Toxoplasma gondii type I fatty acid synthase, putative 0.003 0.0172 0.036
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0022 0.0096 0.0269
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0216 0.2171 0.7216
Brugia malayi hypothetical protein 0.0021 0.0077 0.0063
Loa Loa (eye worm) RGC/RGC protein kinase 0.0216 0.2171 0.2171
Schistosoma mansoni tensin 0.0314 0.322 0.321
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0314 0.322 0.3216
Brugia malayi SH2 domain containing protein 0.053 0.5535 0.5529
Trichomonas vaginalis conserved hypothetical protein 0.0216 0.2171 0.7216
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0401 0.0395
Loa Loa (eye worm) TK/FAK protein kinase 0.0216 0.2171 0.2171
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Brugia malayi 6-phosphofructokinase 0.0117 0.1107 0.1095
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0077 0.0063
Echinococcus granulosus bloom syndrome protein 0.0023 0.0102 0.0096
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.1764 0.176
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0279 0.0889
Mycobacterium ulcerans lipase LipD 0.0078 0.0695 0.2276
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0232 0.0232
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0059 0.0485 0.048
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.1107 0.3655
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0194 0.0406
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0216 0.2171 0.2166
Loa Loa (eye worm) TK/FER protein kinase 0.0216 0.2171 0.2171
Brugia malayi beta-lactamase family protein 0.0078 0.0695 0.0683
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) hypothetical protein 0.0059 0.0485 0.0485
Onchocerca volvulus 0.0216 0.2171 0.3907
Loa Loa (eye worm) hypothetical protein 0.0059 0.0485 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0077 0.0211
Trypanosoma brucei glucosidase, putative 0.0039 0.0279 0.0266
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0077 0.0063
Brugia malayi STAT protein, DNA binding domain containing protein 0.0314 0.322 0.3211
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0285 0.0279
Loa Loa (eye worm) hypothetical protein 0.0059 0.0485 0.0485
Echinococcus multilocularis growth factor receptor bound protein 2 0.0314 0.322 0.3216
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0216 0.2171 0.7216
Echinococcus granulosus suppressor of cytokine signaling 6 0.0314 0.322 0.3216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Brugia malayi Protein kinase domain containing protein 0.053 0.5535 0.5529
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0173 0.1713 0.1709
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Brugia malayi hypothetical protein 0.0216 0.2171 0.216
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0279 0.0481
Onchocerca volvulus 0.0314 0.322 0.5807
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis 0.0314 0.322 0.3216
Schistosoma mansoni ap endonuclease 0.002 0.0072 0.0057
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.053 0.5535 0.5532
Brugia malayi SRC-1 0.053 0.5535 0.5529
Loa Loa (eye worm) glutamate receptor 2 0.0114 0.1084 0.1084
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0143 0.013
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0111 0.1044 0.1044
Plasmodium falciparum tyrosine kinase-like protein 0.0216 0.2171 0.4614
Leishmania major hypothetical protein, conserved 0.0216 0.2171 0.216
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) hypothetical protein 0.0076 0.0668 0.0668
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0695 0.1307
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0401 0.0395
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0052
Trichomonas vaginalis esterase, putative 0.0078 0.0695 0.228
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0173 0.1713 0.1709
Brugia malayi Tyrosine-protein kinase PR2 0.0216 0.2171 0.216
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0578 0.0564
Trichomonas vaginalis protein kinase atn1, putative 0.0216 0.2171 0.7216
Echinococcus multilocularis tyrosine kinase 0.0275 0.28 0.2796
Onchocerca volvulus 0.0048 0.0375 0.0654
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0077 0.0061
Loa Loa (eye worm) hypothetical protein 0.0078 0.0695 0.0695
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Loa Loa (eye worm) glutamate receptor 1 0.0114 0.1084 0.1084
Loa Loa (eye worm) hypothetical protein 0.0059 0.0485 0.0485
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Loa Loa (eye worm) hypothetical protein 0.0059 0.0485 0.0485
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0194 0.0269
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0077 0.0063
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0695 0.1307
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0077 0.0211
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis muscleblind protein 0.0339 0.3489 0.3485
Brugia malayi SH2 domain containing protein 0.0314 0.322 0.3211
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0401 0.0395
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0077 0.0071
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0077 0.0061
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0077 0.0077
Leishmania major cytochrome p450-like protein 0.0015 0.0015 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0216 0.2171 0.7216
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0022 0.0096 0.0737
Brugia malayi PXA domain containing protein 0.0021 0.0077 0.0063
Echinococcus granulosus tyrosine protein kinase Srms 0.053 0.5535 0.5532
Brugia malayi Metabotropic glutamate receptor precursor. 0.0059 0.0485 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Schistosoma mansoni tyrosine kinase 0.053 0.5535 0.5528
Brugia malayi Receptor family ligand binding region containing protein 0.0275 0.28 0.279
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.1107 0.1981
Echinococcus granulosus epidermal growth factor receptor 0.0216 0.2171 0.2166
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0114 0.1084 0.1079
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Brugia malayi SH2 domain containing protein 0.0314 0.322 0.3211
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0102 0.0096
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0114 0.1084 0.1079
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Trypanosoma cruzi protein kinase, putative 0.0216 0.2171 0.216
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0695 0.6228
Echinococcus multilocularis tensin 0.0314 0.322 0.3216
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Echinococcus multilocularis neuropeptide receptor A26 0.0514 0.5366 0.5363
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.1764 0.176
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0695 0.069
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0216 0.2171 0.2171
Mycobacterium ulcerans thioesterase TesA 0.0023 0.0104 0.0298
Toxoplasma gondii hypothetical protein 0.0444 0.4621 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0143 0.0157
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0216 0.2171 0.469
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0216 0.2171 0.2159
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0072 0.011
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0022 0.0096 0.0269
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.003 0.0172 0.144
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus granulosus carbonic anhydrase 0.0444 0.4621 0.4618
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0314 0.322 0.3216
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0279 0.0274
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Leishmania major carbonic anhydrase-like protein 0.0946 1 1
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0216 0.2171 0.2166
Echinococcus multilocularis activated cdc42 kinase 1 0.0216 0.2171 0.2166
Loa Loa (eye worm) glutaminase 0.0293 0.3003 0.3003
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0216 0.2171 0.2166
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus granulosus tyrosine kinase 0.0275 0.28 0.2796
Entamoeba histolytica hypothetical protein 0.0021 0.0077 0.0114
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0314 0.322 0.322
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0077
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0023 0.01 0.0162
Echinococcus multilocularis glutamate receptor 2 0.0173 0.1713 0.1709
Echinococcus granulosus metabotropic glutamate receptor 5 0.0059 0.0485 0.048
Loa Loa (eye worm) hypothetical protein 0.0027 0.0143 0.0143
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0023 0.0104 0.0815
Echinococcus granulosus glutamate receptor subunit protein glur 0.0114 0.1084 0.1079
Echinococcus multilocularis NMDA receptor 0.0114 0.1084 0.1079
Echinococcus multilocularis activin receptor type 0.0216 0.2171 0.2166
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0077 0.0211
Plasmodium vivax tyrosine kinase-like protein, putative 0.0216 0.2171 1
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Loa Loa (eye worm) TK protein kinase 0.0216 0.2171 0.2171
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0279 0.0266
Brugia malayi Glutamate receptor 2 precursor 0.0114 0.1084 0.1072
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0028 0.0154 0.127
Echinococcus granulosus raf serine:threonine protein kinase 0.0216 0.2171 0.2166
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0072 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0216 0.2171 0.7216
Schistosoma mansoni tyrosine kinase 0.053 0.5535 0.5528
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0216 0.2171 0.2159
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.002 0.007 0.0105
Echinococcus granulosus nmda type glutamate receptor 0.0059 0.0485 0.048
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0279 0.0889
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0216 0.2171 0.216
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0072 0.0235
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Mycobacterium leprae Polyketide synthase Pks13 0.0042 0.0301 0.262
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0028 0.0154 0.0141
Schistosoma mansoni carbonic anhydrase-related 0.0444 0.4621 0.4613
Schistosoma mansoni hypothetical protein 0.0314 0.322 0.321
Loa Loa (eye worm) RecQ helicase 0.0023 0.0102 0.0102
Schistosoma mansoni hypothetical protein 0.0573 0.5996 0.599
Echinococcus granulosus protein kinase 0.0216 0.2171 0.2166
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0578 0.0578
Brugia malayi hypothetical protein 0.0027 0.0143 0.013
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0216 0.2171 0.2166
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0946 1 1
Onchocerca volvulus 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.053 0.5535 0.5532
Echinococcus granulosus carbonic anhydrase II 0.0946 1 1
Schistosoma mansoni nck2/grb4 0.0314 0.322 0.321
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0194 0.08
Echinococcus granulosus fibroblast growth factor receptor 4 0.0216 0.2171 0.2166
Schistosoma mansoni ATP-binding cassette transporter 0.0114 0.1084 0.107
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0279 0.0889
Onchocerca volvulus 0.053 0.5535 1
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.1107 0.3658
Echinococcus multilocularis musashi 0.0029 0.0166 0.0161
Trypanosoma brucei carbonic anhydrase-like protein 0.0946 1 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0023
Echinococcus granulosus SHC transforming protein 3 0.0314 0.322 0.3216
Echinococcus multilocularis tyrosine protein kinase Fgr 0.053 0.5535 0.5532
Echinococcus granulosus glutamate NMDA receptor subunit 0.0114 0.1084 0.1079
Echinococcus granulosus SH2 motif 0.0314 0.322 0.3216
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0695 0.0681
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0946 1 1
Leishmania major hypothetical protein, conserved 0.0078 0.0695 0.0683
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0077 0.0211
Echinococcus multilocularis protein tyrosine kinase 0.0216 0.2171 0.2166
Mycobacterium ulcerans polyketide synthase 0.003 0.0172 0.0526
Echinococcus granulosus epidermal growth factor receptor 0.0216 0.2171 0.2166
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0216 0.2171 0.216
Loa Loa (eye worm) glutaminase 2 0.0293 0.3003 0.3003
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0077
Echinococcus multilocularis NCK adaptor protein 0.0314 0.322 0.3216
Onchocerca volvulus 0.0078 0.0695 0.1235
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.053 0.5535 0.5532
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Loa Loa (eye worm) hypothetical protein 0.0078 0.0695 0.0695
Plasmodium falciparum protein kinase, putative 0.0216 0.2171 0.4614
Mycobacterium ulcerans thioesterase 0.0023 0.0104 0.0298
Brugia malayi intermediate filament protein 0.0029 0.0166 0.0153
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0077 0.0071
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.0695 0.2276
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0578 0.0578
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0015 0.0002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0161 0.0161
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.1107 0.3658
Loa Loa (eye worm) TK/ROR protein kinase 0.0216 0.2171 0.2171
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Onchocerca volvulus 0.053 0.5535 1
Echinococcus multilocularis tyrosine protein kinase 0.0216 0.2171 0.2166
Plasmodium falciparum protein kinase, putative 0.0216 0.2171 0.4614
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0028 0.0154 0.127
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0216 0.2171 0.2171
Loa Loa (eye worm) hypothetical protein 0.0078 0.0695 0.0695
Echinococcus granulosus suppressor of cytokine signaling 7 0.0314 0.322 0.3216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0077
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.003 0.0172 0.0302
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.2171 0.2159
Mycobacterium ulcerans Type I modular polyketide synthase 0.0028 0.0154 0.0464
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0194 0.0603
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Echinococcus multilocularis nmda type glutamate receptor 0.0408 0.4231 0.4228
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0314 0.322 0.321
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Trichomonas vaginalis conserved hypothetical protein 0.0216 0.2171 0.7216
Loa Loa (eye worm) hypothetical protein 0.0444 0.4621 0.4621
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0314 0.322 0.3216
Echinococcus multilocularis protein kinase 0.0216 0.2171 0.2166
Leishmania major protein kinase, putative 0.0216 0.2171 0.216
Schistosoma mansoni metabotropic glutamate receptor 0.0059 0.0485 0.0471
Onchocerca volvulus 0.0275 0.28 0.5047
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0216 0.2171 0.469
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0279 0.0889
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0314 0.322 0.322
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0143 0.0296
Mycobacterium tuberculosis Conserved protein 0.0078 0.0695 0.1307
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica receptor protein kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) hypothetical protein 0.0216 0.2171 0.2171
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0072 0.0059
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0143 0.013
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0578 0.0564
Schistosoma mansoni glutamate receptor kainate 0.0114 0.1084 0.107
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0216 0.2171 0.2166
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0072 0.0072
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.003 0.0172 0.0302
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0015 0.0002
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Loa Loa (eye worm) hypothetical protein 0.0059 0.0485 0.0485
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0059 0.0485 0.048
Echinococcus granulosus SH2 domain containing protein 7 0.0314 0.322 0.3216
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.1107 0.1107
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0216 0.2171 0.2166
Loa Loa (eye worm) serine/threonine protein kinase 0.0216 0.2171 0.2171
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0232 0.0226
Echinococcus multilocularis epidermal growth factor receptor 0.0216 0.2171 0.2166
Echinococcus multilocularis geminin 0.0573 0.5996 0.5994
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0216 0.2171 0.2166
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.053 0.5535 0.5532
Entamoeba histolytica serine/threonine kinase, putative 0.0216 0.2171 0.3907
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0173 0.1713 0.1709
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0216 0.2171 0.216
Brugia malayi beta-lactamase 0.0078 0.0695 0.0683
Echinococcus multilocularis protein kinase 0.0216 0.2171 0.2166
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0293 0.3003 1
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Onchocerca volvulus 0.0314 0.322 0.5807
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0216 0.2171 0.2166
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0695 0.228
Brugia malayi Protein kinase domain containing protein 0.053 0.5535 0.5529
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0279 0.0279
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0114 0.1084 0.1079
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Brugia malayi SH2 domain containing protein 0.0314 0.322 0.3211
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine protein kinase Fyn 0.053 0.5535 0.5532
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Schistosoma mansoni adapter molecule crk 0.0314 0.322 0.321
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0408 0.4231 0.4228
Echinococcus multilocularis lamin dm0 0.0029 0.0166 0.0161
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0216 0.2171 0.2159
Toxoplasma gondii STE kinase 0.0216 0.2171 0.469
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Echinococcus multilocularis carbonic anhydrase 0.0444 0.4621 0.4618
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0072 0.5
Entamoeba histolytica serine/threonine kinase, putative 0.0216 0.2171 0.3907
Leishmania major cytochrome p450-like protein 0.0015 0.0015 0.0002
Mycobacterium ulcerans polyketide synthase Pks13 0.0042 0.0301 0.0957
Brugia malayi Variant SH3 domain containing protein 0.0314 0.322 0.3211
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0077 0.0071
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Echinococcus granulosus activated cdc42 kinase 1 0.0216 0.2171 0.2166
Echinococcus multilocularis c src tyrosine kinase 0.053 0.5535 0.5532
Schistosoma mansoni suppressor of cytokine signaling 0.0314 0.322 0.321
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0022 0.0009
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0444 0.4621 0.4621
Giardia lamblia Kinase 0.0216 0.2171 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0216 0.2171 0.216
Giardia lamblia Kinase, NEK 0.0216 0.2171 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.053 0.5535 0.5532
Brugia malayi TAR-binding protein 0.0067 0.0578 0.0565
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.1764 0.176
Trichomonas vaginalis glutaminase, putative 0.0293 0.3003 1
Onchocerca volvulus 0.0029 0.0166 0.0277
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Brugia malayi Protein kinase domain containing protein 0.0216 0.2171 0.216
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0077 0.0071
Echinococcus multilocularis SH2 motif 0.0314 0.322 0.3216
Schistosoma mansoni alpha-glucosidase 0.0153 0.1499 0.1486
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0077
Echinococcus granulosus retinal guanylyl cyclase 2 0.0216 0.2171 0.2166
Schistosoma mansoni protein kinase 0.0216 0.2171 0.2159
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0077 0.0071
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Echinococcus granulosus ephrin type A receptor 4 A 0.0216 0.2171 0.2166
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0444 0.4621 0.4614
Plasmodium falciparum carbonic anhydrase 0.0444 0.4621 1
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Echinococcus multilocularis ephrin type A receptor 4 A 0.0216 0.2171 0.2166
Echinococcus multilocularis glutamate receptor 2 0.0059 0.0485 0.048
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0173 0.1713 0.1709
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Brugia malayi Variant SH3 domain containing protein 0.0314 0.322 0.3211
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0015 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0314 0.322 0.321
Trypanosoma cruzi extracellular receptor, putative 0.0059 0.0485 0.0472
Entamoeba histolytica receptor protein kinase, putative 0.0216 0.2171 0.3907
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0314 0.322 0.3216
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0216 0.2171 0.2166
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0314 0.322 0.5807
Entamoeba histolytica SH2-protein kinase domain containing protein 0.053 0.5535 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.1107 0.2099
Brugia malayi integrin-linked kinase 0.0216 0.2171 0.216
Loa Loa (eye worm) RGC/RGC protein kinase 0.0275 0.28 0.28
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0216 0.2171 0.2171
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0695 0.069
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0072 0.0059
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0314 0.322 0.3216
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0946 1 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0216 0.2171 0.2166
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0216 0.2171 0.3907
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0216 0.2171 0.2166
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0695 0.0683
Leishmania major extracellular receptor, putative 0.0059 0.0485 0.0472
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0216 0.2171 0.469
Mycobacterium tuberculosis Polyketide synthase Pks12 0.003 0.0172 0.0302
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0946 1 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0232 0.0226
Schistosoma mansoni tyrosine kinase 0.0216 0.2171 0.2159
Loa Loa (eye worm) TK/ACK protein kinase 0.0216 0.2171 0.2171
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0401 0.0386
Brugia malayi PXA domain containing protein 0.0021 0.0077 0.0063
Brugia malayi hypothetical protein 0.004 0.0285 0.0271
Schistosoma mansoni tyrosine kinase 0.053 0.5535 0.5528
Echinococcus multilocularis tyrosine protein kinase Blk 0.053 0.5535 0.5532
Echinococcus multilocularis GPCR, family 2 0.0035 0.0232 0.0226
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.053 0.5535 0.5528
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0216 0.2171 0.2166
Schistosoma mansoni glutamate receptor NMDA 0.0114 0.1084 0.107
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.1107 0.1094
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0216 0.2171 0.216
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0216 0.2171 0.2166
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0059 0.0485 0.0472
Loa Loa (eye worm) hypothetical protein 0.0314 0.322 0.322
Echinococcus multilocularis natriuretic peptide receptor 1 0.0216 0.2171 0.2166
Schistosoma mansoni metabotropic glutamate receptor 0.0059 0.0485 0.0471
Plasmodium vivax tyrosine kinase-like protein, putative 0.0216 0.2171 1
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Brugia malayi protein-tyrosine kinase 0.053 0.5535 0.5529
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0279 0.0266
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.2171 0.3907
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0077 0.0061
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0314 0.322 0.3216
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0314 0.322 0.322
Loa Loa (eye worm) hypothetical protein 0.0059 0.0485 0.0485
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0077 0.0061
Echinococcus granulosus hypothetical protein 0.0314 0.322 0.3216
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0216 0.2171 0.216
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0018 0.0049 0.0093
Entamoeba histolytica hypothetical protein 0.0216 0.2171 0.3907
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0279 0.0274
Brugia malayi cytochrome P450 0.0015 0.0015 0.0002
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0275 0.28 0.5047
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.1107 1
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Entamoeba histolytica protein kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) TK/FER protein kinase 0.053 0.5535 0.5535
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0216 0.2171 0.2159
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0578 0.0564
Mycobacterium tuberculosis Possible penicillin-binding protein 0.05 0.5219 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0194 0.0579
Trichomonas vaginalis TKL family protein kinase 0.0216 0.2171 0.7216
Echinococcus multilocularis lamin 0.0029 0.0166 0.0161
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0077 0.0071
Mycobacterium leprae Probable lipase LipE 0.0078 0.0695 0.6228
Brugia malayi metabotropic glutamate receptor type 2 0.0059 0.0485 0.0472
Mycobacterium leprae Probable polyketide synthase Pks1 0.003 0.0172 0.144
Echinococcus granulosus carbonic anhydrase 0.0444 0.4621 0.4618
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.003 0.0172 0.144
Entamoeba histolytica tyrosine kinase, putative 0.0216 0.2171 0.3907
Loa Loa (eye worm) TK/INSR protein kinase 0.0216 0.2171 0.2171

Activities

Activity type Activity value Assay description Source Reference
p nMED (functional) = 12.44 Minimum effective dose required to induce intestinal secretion in suckling mice ChEMBL. 11931628

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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