Detailed information for compound 415927

Basic information

Technical information
  • TDR Targets ID: 415927
  • Name: N-tert-butyl-2-(1H-indol-3-yl)-2-oxoacetamide
  • MW: 244.289 | Formula: C14H16N2O2
  • H donors: 2 H acceptors: 2 LogP: 2.19 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C(=O)c1c[nH]c2c1cccc2)NC(C)(C)C
  • InChi: 1S/C14H16N2O2/c1-14(2,3)16-13(18)12(17)10-8-15-11-7-5-4-6-9(10)11/h4-8,15H,1-3H3,(H,16,18)
  • InChiKey: BWRIXCIVVJNFFX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-tert-butyl-2-(1H-indol-3-yl)-2-oxo-acetamide
  • N-tert-butyl-2-(1H-indol-3-yl)-2-oxo-ethanamide
  • N-tert-butyl-2-(1H-indol-3-yl)-2-keto-acetamide
  • Acetamide, N-tert-butyl-2-(1H-indol-3-yl)-2-oxo-
  • ZINC01803421
  • BAS 04280182
  • A2902/0122285

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni DNA helicase recq1 0.002 0.005 0.0115
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.005 0.0443
Echinococcus granulosus tubulin beta 4A class IVa 0.0179 0.1121 0.1121
Leishmania major beta tubulin 0.0179 0.1121 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0179 0.1121 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0172 0.1538
Echinococcus granulosus tubulin alpha chain 0.0113 0.067 0.067
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.0066 0.0281
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0023 0.0023
Treponema pallidum cell division protein FtsZ 0.0038 0.0168 0.0181
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0307 0.2738
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Brugia malayi Tubulin alpha-2 chain 0.0113 0.067 0.2354
Plasmodium falciparum tubulin epsilon chain, putative 0.0088 0.0502 0.4478
Giardia lamblia Alpha-tubulin 0.0113 0.067 0.5981
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0028 0.0099 0.0448
Echinococcus granulosus Tubulin beta 2C chain 0.0179 0.1121 0.1121
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.0895 0.0895
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0172 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0239 0.0555
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0019 0.004 0.014
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0249 0.0249
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0249 0.222
Leishmania major carbonic anhydrase-like protein 0.0084 0.0475 0.4239
Leishmania major beta tubulin 0.0179 0.1121 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0249 0.222
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0075 0.0414 0.2051
Loa Loa (eye worm) tubulin beta-2A chain 0.0179 0.1121 0.5648
Echinococcus granulosus tubulin delta chain 0.0038 0.0168 0.0168
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0239 0.0555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Schistosoma mansoni intermediate filament proteins 0.0032 0.0125 0.0291
Schistosoma mansoni hypothetical protein 0.0028 0.0099 0.0229
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.005 0.005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0239 0.084
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0249 0.0577
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0167 0.1491
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Echinococcus multilocularis hypothetical protein 0.0113 0.067 0.067
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0167 0.1491
Loa Loa (eye worm) tubulin gamma chain 0.0088 0.0502 0.2499
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.1162
Plasmodium vivax delta tubulin, putative 0.0038 0.0168 0.1497
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0084 0.0475 0.2363
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.017 0.017
Brugia malayi Inositol-1 0.0039 0.0172 0.0605
Trypanosoma brucei zeta tubulin, putative 0.0038 0.0168 0.1497
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0075 0.0414 0.2051
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0085 0.0375
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0167 0.1489
Leishmania major beta tubulin 0.0179 0.1121 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0167 0.1296
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0025 0.0025
Echinococcus granulosus peroxisome assembly protein 26 0.0113 0.067 0.067
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0023 0.008
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0019 0.004 0.014
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0167 0.0167
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0559 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0113 0.067 0.5981
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0172 0.1538
Plasmodium vivax thrombospondin-related anonymous protein 0.0028 0.0099 0.0881
Onchocerca volvulus 0.0049 0.0239 0.1097
Schistosoma mansoni alpha tubulin 0.0113 0.067 0.1555
Brugia malayi von Willebrand factor type A domain containing protein 0.0028 0.0099 0.0347
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0239 0.1162
Plasmodium falciparum thrombospondin-related anonymous protein 0.0028 0.0099 0.0881
Trichomonas vaginalis tubulin alpha chain, putative 0.0088 0.0502 0.4478
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0167 0.0181
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0239 0.0239
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0084 0.0475 0.4239
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0249 0.222
Loa Loa (eye worm) hypothetical protein 0.0026 0.0085 0.0375
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.0066 0.0153
Brugia malayi tailless protein 0.0023 0.0066 0.0232
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0172 0.5945
Echinococcus multilocularis cysteine protease 0.0017 0.0025 0.0025
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.005 0.0443
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.1162
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0025 0.0224
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0239 0.1162
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0249 0.222
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0239 0.0555
Trypanosoma brucei zeta tubulin 0.0038 0.0168 0.1497
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0066 0.0232
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0019 0.004 0.014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0895 0.2076
Schistosoma mansoni tubulin subunit epsilon 0.0088 0.0502 0.1164
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.0895 0.0895
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.1162
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0053
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0167 0.1491
Trichomonas vaginalis tubulin beta chain, putative 0.0113 0.067 0.5981
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.0066 0.0281
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.005 0.0443
Leishmania major trypanothione reductase 0.0038 0.0167 0.1489
Brugia malayi hypothetical protein 0.0028 0.0099 0.0347
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0167 0.5765
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0249 0.0249
Echinococcus multilocularis tubulin alpha chain 0.0113 0.067 0.067
Brugia malayi hypothetical protein 0.0026 0.0084 0.0294
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Leishmania major beta tubulin 0.0179 0.1121 1
Loa Loa (eye worm) RecQ helicase 0.002 0.005 0.0198
Echinococcus multilocularis GPCR, family 2 0.0017 0.0023 0.0023
Brugia malayi von Willebrand factor type A domain containing protein 0.0028 0.0099 0.0347
Schistosoma mansoni inositol monophosphatase 0.0039 0.0172 0.04
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.035 0.2274 0.5273
Schistosoma mansoni carbonic anhydrase 0.0019 0.004 0.0093
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.1162
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0239 0.0239
Plasmodium falciparum alpha tubulin 2 0.0113 0.067 0.5981
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0038 0.0168 0.9736
Leishmania major gamma-tubulin 0.0088 0.0502 0.4478
Schistosoma mansoni coup transcription factor 0.0049 0.0239 0.0555
Onchocerca volvulus 0.005 0.0246 0.113
Brugia malayi nuclear hormone receptor 0.0049 0.0239 0.084
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0099 0.0672
Onchocerca volvulus 0.0032 0.0125 0.0514
Giardia lamblia Epsilon tubulin 0.0038 0.0168 0.1497
Onchocerca volvulus 0.0028 0.0099 0.0378
Trypanosoma cruzi tubulin delta chain 0.0038 0.0168 0.1497
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0088
Trypanosoma brucei alpha tubulin 0.0113 0.067 0.5981
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.0066 0.0066
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.029 0.5185
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0088
Brugia malayi nuclear receptor NHR-67 0.0023 0.0066 0.0232
Loa Loa (eye worm) tubulin alpha 2 0.0075 0.0414 0.2051
Brugia malayi hypothetical protein 0.0026 0.0085 0.0297
Loa Loa (eye worm) hypothetical protein 0.0184 0.1155 0.582
Trichomonas vaginalis tubulin epsilon chain, putative 0.0113 0.067 0.5981
Entamoeba histolytica tubulin gamma chain 0.0088 0.0502 0.4351
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0066 0.0066
Brugia malayi intermediate filament protein 0.0032 0.0125 0.044
Onchocerca volvulus 0.0028 0.0099 0.0378
Toxoplasma gondii alpha-tubulin I, putative 0.0113 0.067 0.5981
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0085 0.0196
Brugia malayi glutathione reductase 0.0038 0.0167 0.0586
Trypanosoma brucei epsilon tubulin 0.0088 0.0502 0.4478
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0345 0.3074
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0239 0.1097
Echinococcus granulosus Tubulin alpha 1 chain 0.0113 0.067 0.067
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0023 0.0023
Trypanosoma brucei alpha tubulin 0.0113 0.067 0.5981
Trichomonas vaginalis tubulin beta chain, putative 0.005 0.0246 0.2191
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0239 0.0239
Brugia malayi Nuclear hormone receptor E75 0.0023 0.0066 0.0232
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.1162
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.002
Leishmania major beta tubulin 0.0179 0.1121 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0084 0.0747
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0148
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0028 0.0099 0.0448
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0249 0.1211
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0019 0.004 0.0148
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Trypanosoma brucei beta tubulin 0.0179 0.1121 1
Loa Loa (eye worm) tubulin alpha 2 0.0075 0.0414 0.2051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0132 0.1175
Echinococcus multilocularis peroxisome assembly protein 26 0.0113 0.067 0.067
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0084 0.0475 0.4239
Loa Loa (eye worm) hypothetical protein 0.0063 0.0336 0.1656
Echinococcus multilocularis carbonic anhydrase 0.0019 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Echinococcus multilocularis beta tubulin 0.0179 0.1121 0.1121
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0038 0.0168 0.1497
Giardia lamblia Beta tubulin 0.0179 0.1121 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0167 0.0795
Treponema pallidum hypothetical protein 0.0028 0.0099 0.0107
Loa Loa (eye worm) hypothetical protein 0.0113 0.067 0.3356
Trichomonas vaginalis tubulin epsilon chain, putative 0.0113 0.067 0.5981
Brugia malayi von Willebrand factor type A domain containing protein 0.0028 0.0099 0.0347
Trypanosoma cruzi tubulin delta chain 0.0038 0.0168 0.1497
Loa Loa (eye worm) beta-tubulin 0.0179 0.1121 0.5648
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0249 0.222
Loa Loa (eye worm) tubulin beta chain 0.0179 0.1121 0.5648
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0172 0.1344
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0168 0.1497
Brugia malayi hypothetical protein 0.0023 0.0066 0.0232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Plasmodium falciparum tubulin gamma chain 0.0088 0.0502 0.4478
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0239 0.084
Trichomonas vaginalis tubulin alpha chain, putative 0.0179 0.1121 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.0066 0.0153
Schistosoma mansoni carbonic anhydrase-related 0.0019 0.004 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0084 0.0747
Brugia malayi Thioredoxin reductase 0.0038 0.0167 0.0586
Brugia malayi beta-tubulin, identical 0.0179 0.1121 0.3935
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0249 0.0249
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0132 0.0132
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.005 0.005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.005 0.0443
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0066 0.021
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0088 0.0502 0.4478
Echinococcus multilocularis tubulin alpha 3 chain 0.0113 0.067 0.067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Brugia malayi Tubulin alpha chain 0.0038 0.0168 0.0589
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Treponema pallidum 76K protein 0.0028 0.0099 0.0107
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0494 0.8837
Echinococcus multilocularis Tubulin beta 2C chain 0.0179 0.1121 0.1121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0239 0.1162
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0239 0.084
Schistosoma mansoni serine-rich repeat protein 0.0351 0.2281 0.529
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.005 0.005
Echinococcus multilocularis carbonic anhydrase 0.0019 0.004 0.004
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.0066 0.021
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.0066 0.0066
Trypanosoma brucei alpha tubulin 0.0113 0.067 0.5981
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0249 0.0249
Onchocerca volvulus 0.0028 0.0099 0.0378
Entamoeba histolytica tubulin alpha-1 chain 0.0113 0.067 0.5888
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.005 0.005
Loa Loa (eye worm) BEN-1 protein 0.0179 0.1121 0.5648
Toxoplasma gondii beta-tubulin, putative 0.0179 0.1121 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0239 0.0239
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Schistosoma mansoni carbonic anhydrase-related 0.0019 0.004 0.0093
Trichomonas vaginalis tubulin beta chain, putative 0.0113 0.067 0.5981
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0146 0.0895 0.45
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0148
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0066 0.0066
Loa Loa (eye worm) tubulin alpha chain 0.0113 0.067 0.3356
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0132 0.0132
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.005 0.0246 0.2191
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Trypanosoma cruzi zeta tubulin, putative 0.0038 0.0168 0.1497
Echinococcus granulosus carbonic anhydrase 0.0019 0.004 0.004
Brugia malayi Tubulin alpha-2 chain 0.0113 0.067 0.2354
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0132 0.0132
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.005 0.0443
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0028 0.0099 0.0881
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.005 0.0443
Trypanosoma cruzi beta tubulin, putative 0.0179 0.1121 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0113 0.067 0.067
Echinococcus granulosus carbonic anhydrase 0.0019 0.004 0.004
Brugia malayi von Willebrand factor type A domain containing protein 0.0028 0.0099 0.0347
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0167 0.2985
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0099 0.0347
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0132 0.1175
Plasmodium falciparum tubulin delta chain, putative 0.0038 0.0168 0.1497
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.0895 0.0895
Giardia lamblia Delta tubulin 0.0038 0.0168 0.1497
Echinococcus granulosus Tubulin beta 2C chain 0.0179 0.1121 0.1121
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0172 0.1538
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0085 0.0297
Brugia malayi MAP kinase sur-1 0.005 0.0249 0.0874
Toxoplasma gondii cathepsin CPL 0.0017 0.0025 0.0224
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0239 0.0239
Leishmania major epsilon tubulin, putative 0.0088 0.0502 0.4478
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0246 0.2191
Mycobacterium tuberculosis Probable reductase 0.0086 0.0494 0.8837
Toxoplasma gondii beta-1 tubulin, putative 0.0179 0.1121 1
Leishmania major beta tubulin 0.0179 0.1121 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.029 0.1018
Loa Loa (eye worm) tubulin alpha-3 chain 0.0063 0.0336 0.1656
Echinococcus multilocularis Tubulin beta 2C chain 0.0179 0.1121 0.1121
Schistosoma mansoni tubulin subunit beta 0.0179 0.1121 0.26
Echinococcus granulosus voltage dependent calcium channel subunit 0.068 0.45 0.45
Giardia lamblia Gamma tubulin 0.0088 0.0502 0.4478
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0023 0.008
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0125 0.0583
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0084 0.0747
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0025 0.0058
Brugia malayi Tubulin alpha chain 0.0113 0.067 0.2354
Brugia malayi isocitrate dehydrogenase 0.0033 0.0132 0.0462
Schistosoma mansoni ap endonuclease 0.0038 0.0167 0.0388
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0239 0.0555
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0013 0 0.5
Echinococcus multilocularis geminin 0.035 0.2274 0.2274
Plasmodium vivax tubulin beta chain, putative 0.0179 0.1121 1
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0019 0.004 0.014
Trichomonas vaginalis tubulin gamma chain, putative 0.0088 0.0502 0.4478
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0895 0.2076
Brugia malayi nuclear receptor NHR-88 0.0049 0.0239 0.084
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0167 0.2989
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0239 0.0555
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0167 0.0587
Schistosoma mansoni inositol monophosphatase 0.0039 0.0172 0.04
Plasmodium falciparum thioredoxin reductase 0.0038 0.0167 0.1489
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Loa Loa (eye worm) glutathione reductase 0.0038 0.0167 0.0794
Echinococcus multilocularis tubulin gamma 1 chain 0.0088 0.0502 0.0502
Echinococcus granulosus tubulin alpha chain 0.0113 0.067 0.067
Brugia malayi nuclear receptor RXR 0.0026 0.0085 0.0297
Trichomonas vaginalis tubulin epsilon chain, putative 0.0179 0.1121 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0172 0.1538
Echinococcus multilocularis tubulin alpha chain 0.0113 0.067 0.067
Schistosoma mansoni tubulin subunit alpha 0.0113 0.067 0.1555
Brugia malayi Zona pellucida-like domain containing protein 0.0028 0.0099 0.0347
Loa Loa (eye worm) tubulin alpha-2 chain 0.0113 0.067 0.3356
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0172 0.1538
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0023 0.0023
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.0066 0.0066
Entamoeba histolytica elongation factor-2 kinase, putative 0.0028 0.0099 0.0672
Brugia malayi hypothetical protein 0.0026 0.0085 0.0297
Echinococcus multilocularis tubulin alpha 0.0088 0.0502 0.0502
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0025 0.0224
Echinococcus multilocularis lamin 0.0032 0.0125 0.0125
Brugia malayi tubulin alpha chain - mouse 0.0113 0.067 0.2354
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Loa Loa (eye worm) hypothetical protein 0.0123 0.0739 0.3704
Brugia malayi hypothetical protein 0.0023 0.0066 0.0232
Echinococcus granulosus tubulin alpha chain 0.0113 0.067 0.067
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0132 0.0462
Echinococcus multilocularis carbonic anhydrase 0.0019 0.004 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0345 0.3074
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0084 0.0475 0.1102
Brugia malayi Tubulin gamma chain 0.0088 0.0502 0.1762
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0084 0.0747
Loa Loa (eye worm) hypothetical protein 0.0032 0.0125 0.0583
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0084 0.0747
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0239 0.0239
Loa Loa (eye worm) hypothetical protein 0.0036 0.0152 0.0719
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0559 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0066 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0249 0.222
Schistosoma mansoni nuclear receptor 0.0023 0.0066 0.0153
Onchocerca volvulus Huntingtin homolog 0.0123 0.0739 0.3658
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0265 0.129
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0061
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0239 0.1162
Trypanosoma brucei beta tubulin 0.0179 0.1121 1
Entamoeba histolytica hypothetical protein 0.0028 0.0099 0.0672
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0066 0.0153
Leishmania major beta tubulin 0.0179 0.1121 1
Echinococcus granulosus cathepsin l1 0.0017 0.0025 0.0025
Brugia malayi conserved hypotetical protein 0.0023 0.0066 0.0232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Trypanosoma cruzi zeta tubulin, putative 0.0038 0.0168 0.1497
Brugia malayi tubulin alpha-2 chain 0.0113 0.067 0.2354
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0249 0.222
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0132 0.1175
Echinococcus granulosus lamin dm0 0.0032 0.0125 0.0125
Echinococcus granulosus tubulin alpha 3 chain 0.0113 0.067 0.067
Loa Loa (eye worm) CUTiclin family member 0.0028 0.0099 0.0448
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0023 0.0061
Trypanosoma brucei carbonic anhydrase-like protein 0.0084 0.0475 0.4239
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0132 0.1175
Mycobacterium tuberculosis Cell division protein FtsZ 0.0038 0.0168 0.3001
Schistosoma mansoni tubulin subunit beta 0.0038 0.0168 0.0389
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0088
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0172 0.1538
Leishmania major hypothetical protein, conserved 0.0026 0.0084 0.0747
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0167 0.1491
Trichomonas vaginalis tubulin gamma chain, putative 0.0179 0.1121 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0113 0.067 0.067
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0084 0.0475 0.1668
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.0895 0.0895
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0088
Echinococcus granulosus carbonic anhydrase II 0.0084 0.0475 0.0475
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0239 0.084
Echinococcus multilocularis carbonic anhydrase II 0.0084 0.0475 0.0475
Trypanosoma brucei beta tubulin 0.0088 0.0502 0.4478
Loa Loa (eye worm) hypothetical protein 0.0026 0.0085 0.0375
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.005 0.0443
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0038 0.0168 0.1497
Echinococcus multilocularis tubulin alpha 3 chain 0.0113 0.067 0.067
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0239 0.0239
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0167 0.0794
Leishmania major beta tubulin 0.0179 0.1121 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0113 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0132 0.1175
Loa Loa (eye worm) tubulin beta chain 0.0038 0.0168 0.0799
Echinococcus granulosus tubulin gamma 1 chain 0.0088 0.0502 0.0502
Echinococcus multilocularis tubulin alpha 1C chain 0.0113 0.067 0.067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0895 0.2076
Brugia malayi nuclear receptor RXR 0.0023 0.0066 0.0232
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0224
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0224
Entamoeba histolytica recQ family helicase, putative 0.002 0.005 0.0224
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0239 0.0555
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.0066 0.0232
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0172 0.1538
Echinococcus multilocularis tubulin alpha chain 0.0113 0.067 0.067
Echinococcus multilocularis tubulin subunit TubB 0.0113 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0239 0.0555
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0085 0.0297
Brugia malayi photoreceptor-specific nuclear receptor 0.0049 0.0239 0.084
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0239 0.084
Leishmania major beta tubulin 0.0179 0.1121 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0132 0.0132
Brugia malayi Cell division protein ftsZ 0.0038 0.0168 0.0589
Toxoplasma gondii exonuclease III APE 0.0038 0.0167 0.1491
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Echinococcus granulosus tubulin subunit beta 0.0179 0.1121 0.1121
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0239 0.0239
Schistosoma mansoni hypothetical protein 0.035 0.2274 0.5273
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0239 0.0239
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0063 0.0336 0.3
Plasmodium falciparum tubulin beta chain 0.0179 0.1121 1
Leishmania major beta tubulin 0.0179 0.1121 1
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0246 0.2191
Brugia malayi Tubulin beta-1 chain 0.0179 0.1121 0.3935
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0239 0.0239
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0559 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0239 0.084
Echinococcus granulosus tubulin subunit TubB 0.0113 0.067 0.067
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0026 0.0078
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0025 0.0073
Echinococcus granulosus Tubulin beta 2C chain 0.0179 0.1121 0.1121
Entamoeba histolytica tubulin family protein 0.0179 0.1121 1
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0167 0.1491
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.005 0.0443
Echinococcus granulosus Tubulin beta 2C chain 0.0179 0.1121 0.1121
Echinococcus granulosus tubulin alpha 1C chain 0.0113 0.067 0.067
Trichomonas vaginalis tubulin, putative 0.005 0.0246 0.2191
Toxoplasma gondii alpha tubulin TUBA1 0.0113 0.067 0.5981
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0224
Leishmania major cathepsin L-like protease 0.0064 0.0345 0.3074
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0249 0.222
Giardia lamblia Alpha-tubulin 0.0113 0.067 0.5981
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0028 0.0099 0.0099
Echinococcus granulosus tubulin alpha 1C chain 0.0113 0.067 0.067
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0025 0.0224
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0494 0.8837
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0494 0.8837
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.0066 0.0232
Plasmodium vivax vivapain-2 0.0017 0.0025 0.0224
Loa Loa (eye worm) tubulin alpha chain 0.0113 0.067 0.3356
Schistosoma mansoni carbonic anhydrase-related 0.0019 0.004 0.0093
Echinococcus multilocularis cysteine protease 0.0017 0.0025 0.0025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.0066 0.0066
Brugia malayi Tubulin beta chain 0.005 0.0246 0.0862
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.1162
Trypanosoma cruzi alpha tubulin, putative 0.0113 0.067 0.5981
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.005 0.0174
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Loa Loa (eye worm) hypothetical protein 0.0026 0.0084 0.0371
Loa Loa (eye worm) hypothetical protein 0.0123 0.0739 0.3704
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.0066 0.0066
Plasmodium vivax vivapain-2 0.0017 0.0025 0.0224
Trypanosoma brucei beta tubulin 0.0179 0.1121 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Mycobacterium ulcerans cell division protein FtsZ 0.0038 0.0168 0.5789
Brugia malayi ecdysteroid receptor 0.0049 0.0239 0.084
Loa Loa (eye worm) hypothetical protein 0.0026 0.0085 0.0375
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0172 0.0172
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0494 0.8837
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.0066 0.0232
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0073
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0198
Plasmodium falciparum glutathione reductase 0.0038 0.0167 0.1489
Schistosoma mansoni lamin 0.0032 0.0125 0.0291
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0345 0.3074
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0167 0.1491
Schistosoma mansoni tubulin subunit beta 0.0179 0.1121 0.26
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0652 0.4313 1
Loa Loa (eye worm) CUTiclin-Like family member 0.0028 0.0099 0.0448
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0053
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0025 0.0025
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.005 0.0443
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0329 0.213 0.4939
Loa Loa (eye worm) alpha-tubulin 0.0113 0.067 0.3356
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0015 0.0015
Echinococcus multilocularis musashi 0.0032 0.0125 0.0125
Echinococcus granulosus collagen alpha 1VII chain 0.0028 0.0099 0.0099
Trichomonas vaginalis tubulin, putative 0.0038 0.0168 0.1497
Echinococcus granulosus tubulin alpha chain 0.0113 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Loa Loa (eye worm) alpha-tubulin 0.0113 0.067 0.3356
Loa Loa (eye worm) BEN-1 protein 0.0179 0.1121 0.5648
Echinococcus multilocularis beta tubulin 0.0179 0.1121 0.1121
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0125 0.044
Trichomonas vaginalis tubulin, putative 0.005 0.0246 0.2191
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Echinococcus granulosus intermediate filament protein 0.0032 0.0125 0.0125
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0239 0.0239
Schistosoma mansoni alpha tubulin 0.0113 0.067 0.1555
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0028 0.0099 0.0881
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0168 0.1497
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.005 0.0443
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0239 0.0239
Echinococcus granulosus carbonic anhydrase 0.0019 0.004 0.004
Brugia malayi alpha-tubulin 0.0113 0.067 0.2354
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0028 0.0099 0.0881
Brugia malayi hypothetical protein 0.0435 0.2849 1
Schistosoma mansoni ap endonuclease 0.0038 0.0167 0.0388
Echinococcus multilocularis voltage dependent calcium channel subunit 0.068 0.45 0.45
Echinococcus multilocularis tubulin epsilon chain 0.0088 0.0502 0.0502
Trichomonas vaginalis tubulin epsilon chain, putative 0.0038 0.0168 0.1497
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0025 0.0025
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0132 0.1175
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.0066 0.0153
Echinococcus multilocularis tubulin delta chain 0.0038 0.0168 0.0168
Schistosoma mansoni tubulin subunit beta 0.0179 0.1121 0.26
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Trichomonas vaginalis tubulin gamma chain, putative 0.0038 0.0168 0.1497
Schistosoma mansoni tubulin subunit alpha 0.0113 0.067 0.1555
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0239 0.0239
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0239 0.084
Entamoeba histolytica tubulin family protein 0.0179 0.1121 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0025 0.0224
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0085 0.0196
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0167 0.1491
Echinococcus multilocularis Tubulin beta 2C chain 0.0179 0.1121 0.1121
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0132 0.1175
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0239 0.0555
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0239 0.084
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0249 0.222
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0146 0.0895 0.3143
Leishmania major beta tubulin 0.0179 0.1121 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0264 0.0926
Trichomonas vaginalis tubulin beta chain, putative 0.0113 0.067 0.5981
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0038 0.0168 0.1497
Echinococcus multilocularis tubulin subunit beta 0.0179 0.1121 0.1121
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Schistosoma mansoni tubulin subunit beta 0.0179 0.1121 0.26
Echinococcus multilocularis bloom syndrome protein 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0239 0.1162
Loa Loa (eye worm) hypothetical protein 0.0026 0.0085 0.0375
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0239 0.1097
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0249 0.222
Entamoeba histolytica hypothetical protein, conserved 0.0028 0.0099 0.0672
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0167 0.9697
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0224
Onchocerca volvulus 0.0028 0.0099 0.0378
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0066 0.0066
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0132 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Echinococcus granulosus tubulin alpha 0.0088 0.0502 0.0502
Echinococcus granulosus lamin 0.0032 0.0125 0.0125
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.005 0.0198
Onchocerca volvulus 0.0306 0.1977 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0179 0.1121 0.1121
Trypanosoma brucei beta tubulin 0.0179 0.1121 1
Schistosoma mansoni hypothetical protein 0.0019 0.004 0.0093
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0264 0.0926
Loa Loa (eye worm) DR-78 0.0023 0.0066 0.0281
Loa Loa (eye worm) hypothetical protein 0.0052 0.0264 0.1286
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0132 0.2355
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0172 0.1538
Echinococcus multilocularis tubulin alpha chain 0.0113 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Onchocerca volvulus 0.0023 0.0066 0.021
Onchocerca volvulus 0.0028 0.0099 0.0378
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0028 0.0099 0.0881
Leishmania major beta tubulin 0.0179 0.1121 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.1162
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0025 0.0224
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0025 0.0088
Loa Loa (eye worm) tubulin beta-4 chain 0.0179 0.1121 0.5648
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0025 0.0025
Brugia malayi nuclear receptor NHR-88 0.0023 0.0066 0.0232
Toxoplasma gondii microneme protein MIC2 0.0028 0.0099 0.0881
Leishmania major zeta tubulin, putative 0.0038 0.0168 0.1497
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0019 0.004 0.014
Schistosoma mansoni tubulin subunit alpha 0.0038 0.0168 0.0389
Plasmodium vivax tubulin epsilon chain, putative 0.0088 0.0502 0.4478
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0132 0.1175
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0239 0.084
Echinococcus multilocularis tubulin alpha 1C chain 0.0113 0.067 0.067
Plasmodium falciparum carbonic anhydrase 0.0019 0.004 0.0357
Trypanosoma cruzi epsilon tubulin, putative 0.0088 0.0502 0.4478
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0085 0.0085
Echinococcus multilocularis Tubulin beta 2C chain 0.0179 0.1121 0.1121
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0167 0.1491
Trypanosoma brucei trypanothione reductase 0.0038 0.0167 0.1489
Plasmodium vivax tubulin gamma chain, putative 0.0088 0.0502 0.4478
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Loa Loa (eye worm) hypothetical protein 0.0049 0.0239 0.1162
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.029 1
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0345 0.3074
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.1385 0.9254 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.0066 0.0066
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0239 0.0555
Trichomonas vaginalis tubulin beta chain, putative 0.0179 0.1121 1
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0152 0.0534
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0167 0.1491
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.0066 0.0232
Echinococcus granulosus beta tubulin 0.0179 0.1121 0.1121
Brugia malayi ecdysone receptor 0.0023 0.0066 0.0232
Schistosoma mansoni nuclear receptor 0.0023 0.0066 0.0153
Mycobacterium leprae cell division protein FtsZ 0.0038 0.0168 0.055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Loa Loa (eye worm) hypothetical protein 0.0306 0.1977 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0494 0.8837
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0239 0.1162
Schistosoma mansoni tubulin subunit alpha 0.0113 0.067 0.1555
Trypanosoma brucei epsilon tubulin 0.0088 0.0502 0.4478
Onchocerca volvulus 0.0028 0.0099 0.0378
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0249 0.222
Brugia malayi Bloom's syndrome protein homolog 0.002 0.005 0.0174
Plasmodium vivax glutathione reductase, putative 0.0038 0.0167 0.1489
Schistosoma mansoni hypothetical protein 0.0036 0.0152 0.0353
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Echinococcus granulosus tubulin alpha 3 chain 0.0113 0.067 0.067
Brugia malayi Cache domain containing protein 0.0301 0.1943 0.682
Toxoplasma gondii beta tubulin 0.0179 0.1121 1
Leishmania major cathepsin L-like protease 0.0064 0.0345 0.3074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0125 0.0583
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.017 0.017
Brugia malayi hypothetical protein 0.0306 0.1977 0.6938
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Brugia malayi hypothetical protein 0.0123 0.0739 0.2594
Brugia malayi Zona pellucida-like domain containing protein 0.0028 0.0099 0.0347
Plasmodium falciparum alpha tubulin 1 0.0113 0.067 0.5981
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0239 0.1162
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0239 0.0239
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0053
Brugia malayi steroid hormone receptor 0.0049 0.0239 0.084
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0252 0.2247
Loa Loa (eye worm) tubulin alpha 2 0.0025 0.008 0.0352
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0099 0.0881
Onchocerca volvulus 0.0028 0.0099 0.0378
Brugia malayi von Willebrand factor type A domain containing protein 0.0028 0.0099 0.0347
Brugia malayi nuclear hormone receptor 0.0023 0.0066 0.0232
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0028 0.0099 0.0881
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0025 0.0224
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0025 0.0058
Schistosoma mansoni lamin 0.0032 0.0125 0.0291
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0264 0.1286
Loa Loa (eye worm) hypothetical protein 0.0031 0.0122 0.0563
Trypanosoma brucei tubulin gamma chain 0.0088 0.0502 0.4478
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Echinococcus granulosus tubulin epsilon chain 0.0088 0.0502 0.0502
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0028 0.0099 0.0881
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0239 0.084
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0028 0.0099 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0239 0.084
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0239 0.084
Toxoplasma gondii hypothetical protein 0.0019 0.004 0.0357
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.029 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.029 0.2587
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0239 0.1097
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0026 0.0092
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0239 0.0239
Schistosoma mansoni zinc finger protein 0.0023 0.0066 0.0153
Trichomonas vaginalis tubulin beta chain, putative 0.0113 0.067 0.5981
Echinococcus multilocularis tubulin beta 1 chain 0.0179 0.1121 0.1121
Schistosoma mansoni alpha tubulin 0.0113 0.067 0.1555
Echinococcus granulosus Tubulin beta 2C chain 0.0179 0.1121 0.1121
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0025 0.0025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0239 0.1162
Brugia malayi von Willebrand Factor 0.0028 0.0099 0.0347
Trichomonas vaginalis tubulin, putative 0.0179 0.1121 1
Leishmania major beta tubulin 0.0179 0.1121 1
Trypanosoma brucei tubulin delta chain 0.0038 0.0168 0.1497
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Trypanosoma cruzi epsilon tubulin, putative 0.0088 0.0502 0.4478
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0132 0.0305
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.005 0.0174
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0239 0.0239
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.0066 0.0281
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0239 0.0555
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0172 0.0172
Giardia lamblia Beta tubulin 0.0179 0.1121 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0084 0.0747
Echinococcus multilocularis lamin dm0 0.0032 0.0125 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0084 0.0747
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0028 0.0099 0.0881
Echinococcus multilocularis voltage dependent calcium channel subunit 0.1495 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0025 0.0224
Loa Loa (eye worm) inositol-1 0.0039 0.0172 0.0822
Trypanosoma brucei alpha tubulin 0.0113 0.067 0.5981
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0066 0.0153
Leishmania major delta tubulin, putative 0.0038 0.0168 0.1497
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0025 0.0224
Schistosoma mansoni tubulin subunit delta 0.0038 0.0168 0.0389
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0179 0.1121 0.1121
Loa Loa (eye worm) tubulin beta-1 chain 0.0179 0.1121 0.5648
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0239 0.0555
Onchocerca volvulus 0.0023 0.0066 0.021
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0088
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.029 0.0672
Plasmodium vivax tubulin alpha chain, putative 0.0113 0.067 0.5981
Leishmania major cathepsin L-like protease 0.0064 0.0345 0.3074
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0145 0.2594
Leishmania major beta tubulin 0.0179 0.1121 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0085 0.0375
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0239 0.0239
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0494 0.843
Loa Loa (eye worm) cysteine protease 0.0017 0.0025 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0239 0.084
Echinococcus granulosus tubulin alpha chain 0.0113 0.067 0.067
Trypanosoma brucei alpha tubulin, putative 0.005 0.0246 0.2191
Loa Loa (eye worm) fibroinase 0.0017 0.0025 0.0073
Echinococcus granulosus alpha tubulin 0.0113 0.067 0.067
Schistosoma mansoni DNA helicase recq5 0.002 0.005 0.0115
Toxoplasma gondii thioredoxin reductase 0.0038 0.0167 0.1489
Schistosoma mansoni hypothetical protein 0.0028 0.0099 0.0229
Trypanosoma brucei epsilon tubulin 0.0088 0.0502 0.4478
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0084 0.0475 0.1668
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.029 0.029
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0025 0.0073
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0559 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0132 0.1175
Trypanosoma cruzi tubulin gamma chain 0.0088 0.0502 0.4478
Brugia malayi Cathepsin L-like precursor 0.0017 0.0025 0.0088
Schistosoma mansoni hypothetical protein 0.0351 0.2281 0.529
Brugia malayi von Willebrand factor type A domain containing protein 0.0028 0.0099 0.0347
Echinococcus granulosus GPCR family 2 0.0017 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0345 0.3074
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0249 0.222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Leishmania major beta tubulin 0.0179 0.1121 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.0066 0.0066
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.0066 0.0066
Onchocerca volvulus 0.0032 0.0125 0.0514
Loa Loa (eye worm) carbonic anhydrase 3 0.0084 0.0475 0.2363
Echinococcus multilocularis Tubulin alpha 1 chain 0.0113 0.067 0.067
Brugia malayi Tubulin beta chain 0.0038 0.0168 0.0589
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0239 0.0555
Loa Loa (eye worm) hypothetical protein 0.0028 0.0099 0.0448
Entamoeba histolytica tubulin alpha chain, putative 0.0113 0.067 0.5888
Plasmodium vivax tubulin alpha chain, putative 0.0113 0.067 0.5981
Schistosoma mansoni tubulin subunit beta 0.0179 0.1121 0.26
Schistosoma mansoni tubulin subunit beta 0.0179 0.1121 0.26
Brugia malayi hypothetical protein 0.0016 0.0023 0.008
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0246 0.2191
Echinococcus multilocularis tubulin alpha chain 0.0113 0.067 0.067
Leishmania major cathepsin L-like protease 0.0017 0.0025 0.0224
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0075 0.0414 0.3694
Trichomonas vaginalis tubulin gamma chain, putative 0.0088 0.0502 0.4478
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.005 0.0443
Giardia lamblia Beta tubulin 0.0179 0.1121 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0025 0.0224
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0167 0.1489
Loa Loa (eye worm) hypothetical protein 0.0301 0.1943 0.9828
Echinococcus granulosus geminin 0.035 0.2274 0.2274
Leishmania major beta tubulin 0.0179 0.1121 1
Echinococcus granulosus tubulin beta 1 chain 0.0179 0.1121 0.1121
Loa Loa (eye worm) hypothetical protein 0.0023 0.0066 0.0281
Brugia malayi von Willebrand factor type A domain containing protein 0.0028 0.0099 0.0347
Echinococcus granulosus beta tubulin 0.0179 0.1121 0.1121
Leishmania major alpha tubulin 0.0113 0.067 0.5981
Brugia malayi von Willebrand factor type A domain containing protein 0.0028 0.0099 0.0347
Echinococcus granulosus bloom syndrome protein 0.002 0.005 0.005
Trichomonas vaginalis tubulin beta chain, putative 0.0113 0.067 0.5981
Trypanosoma brucei protein kinase, putative 0.005 0.0249 0.222
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0132 0.0615
Echinococcus multilocularis Tubulin alpha 1 chain 0.0113 0.067 0.067
Loa Loa (eye worm) ctsf protein 0.0017 0.0025 0.0073
Leishmania major beta tubulin 0.0179 0.1121 1
Schistosoma mansoni tubulin subunit gamma 0.0088 0.0502 0.1164
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0249 0.222
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0084 0.0475 0.1102
Trichomonas vaginalis tubulin beta chain, putative 0.0113 0.067 0.5981
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0239 0.084
Onchocerca volvulus Huntingtin homolog 0.0123 0.0739 0.3658
Leishmania major beta tubulin 0.0179 0.1121 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0239 0.084

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 7 % Displacement of [3H]flumazenil from benzodiazepine receptor in bovine brain membranes at 10 uM ChEMBL. 17335185

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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