Detailed information for compound 645809

Basic information

Technical information
  • TDR Targets ID: 645809
  • Name: 2-[(2-methoxyphenyl)-phenylsulfonylamino]-N-p rop-2-enylacetamide
  • MW: 360.427 | Formula: C18H20N2O4S
  • H donors: 1 H acceptors: 3 LogP: 2.59 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCNC(=O)CN(S(=O)(=O)c1ccccc1)c1ccccc1OC
  • InChi: 1S/C18H20N2O4S/c1-3-13-19-18(21)14-20(16-11-7-8-12-17(16)24-2)25(22,23)15-9-5-4-6-10-15/h3-12H,1,13-14H2,2H3,(H,19,21)
  • InChiKey: LFSGRKSSAUJPKK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-allyl-2-[(2-methoxyphenyl)-phenylsulfonyl-amino]acetamide
  • N-allyl-2-[(2-methoxyphenyl)-phenylsulfonylamino]acetamide
  • 2-[(2-methoxyphenyl)-phenylsulfonyl-amino]-N-prop-2-enyl-ethanamide
  • AG-690/15439529
  • ZINC02064810
  • BAS 02187440
  • N-Allyl-2-[benzenesulfonyl-(2-methoxy-phenyl)-amino]-acetamide
  • CBMicro_012099
  • BIM-0011918.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) MH2 domain-containing protein 0.0021 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0112 0.0382 0.1048
Loa Loa (eye worm) hypothetical protein 0.0451 0.1756 0.4817
Brugia malayi MH1 domain containing protein 0.0027 0.0034 0.0092
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0031 0.0052 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0088 0.024
Loa Loa (eye worm) MH1 domain-containing protein 0.0021 0.0013 0.0036
Echinococcus multilocularis aldo keto reductase 0.0134 0.047 0.047
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Onchocerca volvulus 0.0985 0.392 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0088 0.024
Brugia malayi nuclear receptor RXR 0.0021 0.0012 0.0031
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0397 0.2877
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0131 0.0459 0.0459
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0021 0.0012 0.0018
Mycobacterium ulcerans hypothetical protein 0.0112 0.0382 0.2871
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0094 0.024
Schistosoma mansoni lamin 0.0026 0.0034 0.0056
Plasmodium vivax ataxin-2 like protein, putative 0.0153 0.0546 1
Schistosoma mansoni smad1 5 8 and 0.0048 0.0121 0.0216
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0003 0.0008
Onchocerca volvulus 0.0134 0.047 0.1193
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0088 0.024
Onchocerca volvulus 0.0134 0.047 0.1193
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0032
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0069 0.0204 0.0373
Giardia lamblia Aldose reductase 0.0134 0.047 1
Schistosoma mansoni jumonji domain containing protein 0.0067 0.0197 0.0355
Brugia malayi beta-lactamase family protein 0.0112 0.0382 0.1048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Trichomonas vaginalis chromobox protein, putative 0.0129 0.0451 0.1151
Trichomonas vaginalis helicase, putative 0.002 0.0008 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0169 0.061 0.111
Brugia malayi beta-lactamase 0.0112 0.0382 0.1048
Schistosoma mansoni hypothetical protein 0.0544 0.2133 0.3895
Echinococcus multilocularis peregrin 0.0042 0.0098 0.0098
Entamoeba histolytica hypothetical protein 0.0039 0.0085 0.1743
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0003 0.0006
Echinococcus granulosus mitogen activated protein kinase 3 0.0077 0.0239 0.0436
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0345 0.1324 0.3632
Leishmania major hypothetical protein, conserved 0.0038 0.0082 0.0712
Schistosoma mansoni coup transcription factor 0.004 0.0088 0.0156
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.1971 0.7914 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0088 0.016
Loa Loa (eye worm) hypothetical protein 0.0058 0.016 0.0438
Brugia malayi mothers against decapentaplegic homolog 3 0.0021 0.0013 0.0036
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0054 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0085
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Brugia malayi glutaminase DH11.1 0.0281 0.1066 0.2924
Echinococcus granulosus methyl CpG binding domain protein 2 0.0043 0.01 0.0182
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Echinococcus multilocularis zinc finger protein 0.0065 0.0189 0.0189
Onchocerca volvulus 0.0147 0.0523 0.1327
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0415 0.1609 0.4414
Loa Loa (eye worm) hypothetical protein 0.0172 0.0624 0.1711
Mycobacterium leprae Conserved hypothetical protein 0.0095 0.0313 0.2225
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0023 0.0151
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0088 0.0088
Onchocerca volvulus 0.0162 0.0585 0.1485
Echinococcus multilocularis mothers against decapentaplegic 6 0.0021 0.0013 0.0013
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0092 0.0164
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.0382 0.1337
Onchocerca volvulus 0.0134 0.047 0.1193
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.0382 0.1048
Brugia malayi Hemopexin family protein 0.0401 0.1554 0.4261
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0131 0.0459 0.0839
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0039 0.0084 0.0731
Loa Loa (eye worm) glutaminase 0.0281 0.1066 0.2924
Trichomonas vaginalis aldo/keto reductase, putative 0.0134 0.047 0.1199
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0048 0.0121 0.0121
Toxoplasma gondii histone lysine methyltransferase SET1 0.0189 0.0694 1
Brugia malayi Matrixin family protein 0.0917 0.3645 1
Loa Loa (eye worm) transcription factor SMAD2 0.0704 0.2779 0.7622
Brugia malayi nuclear receptor NHR-88 0.0019 0.0003 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0178 0.0647 0.1177
Plasmodium falciparum phd finger protein, putative 0.0026 0.0031 0.0504
Entamoeba histolytica aldose reductase, putative 0.0134 0.047 1
Loa Loa (eye worm) hypothetical protein 0.0112 0.0382 0.1048
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Onchocerca volvulus 0.0024 0.0023 0.0052
Loa Loa (eye worm) heterochromatin protein 1 0.0129 0.0451 0.1236
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0012 0.0171
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0021 0.0012 0.0134
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.1109 1
Onchocerca volvulus 0.0401 0.1554 0.3959
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0284 0.1077 0.1964
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0088 0.0156
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0169 0.061 0.061
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0131 0.0459 0.0839
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Toxoplasma gondii thioredoxin reductase 0.0046 0.0112 0.1579
Brugia malayi MAP kinase sur-1 0.0077 0.0239 0.0653
Trichomonas vaginalis CMGC family protein kinase 0.0077 0.0239 0.0608
Onchocerca volvulus 0.0089 0.0287 0.0725
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0036
Toxoplasma gondii ABC1 family protein 0.0112 0.0382 0.5487
Trypanosoma cruzi aldo/keto reductase, putative 0.0039 0.0084 0.0731
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.035 0.1224
Echinococcus multilocularis muscleblind protein 1 0.0172 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Onchocerca volvulus 0.004 0.0088 0.0217
Loa Loa (eye worm) fli-1 protein 0.0164 0.0589 0.1616
Loa Loa (eye worm) hypothetical protein 0.0345 0.1324 0.3632
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0437 0.0437
Loa Loa (eye worm) helicase 0.0021 0.0012 0.0033
Echinococcus granulosus Chromo domain 0.0021 0.0012 0.0023
Brugia malayi MH2 domain containing protein 0.0048 0.0121 0.033
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0088 0.024
Loa Loa (eye worm) MH2 domain-containing protein 0.0704 0.2779 0.7622
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0043 0.01 0.01
Giardia lamblia Histone acetyltransferase GCN5 0.0117 0.0401 0.8517
Loa Loa (eye worm) matrixin family protein 0.0667 0.263 0.7215
Echinococcus granulosus histone lysine methyltransferase setb 0.0169 0.061 0.1115
Loa Loa (eye worm) DR-78 0.0019 0.0003 0.0006
Schistosoma mansoni hypothetical protein 0.0131 0.0459 0.0834
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0718 0.2838 1
Onchocerca volvulus 0.0134 0.047 0.1193
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0239 0.0431
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0031 0.0504
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0088 0.0088
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.0382 0.1337
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0144 0.1273
Schistosoma mansoni lamin 0.0026 0.0034 0.0056
Echinococcus multilocularis musashi 0.0026 0.0034 0.0033
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0054 0.0144 0.3016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0033
Brugia malayi hypothetical protein 0.0019 0.0003 0.0006
Schistosoma mansoni microtubule-associated protein tau 0.1368 0.5472 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0026 0.0031 0.0396
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0345 0.1324 0.4659
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0077 0.0239 0.2128
Brugia malayi Bromodomain containing protein 0.0042 0.0098 0.0267
Schistosoma mansoni hypothetical protein 0.0052 0.0136 0.0244
Echinococcus granulosus jumonji domain containing protein 0.0036 0.0071 0.013
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0284 0.1077 0.2953
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.0382 0.0699
Plasmodium vivax SET domain protein, putative 0.0126 0.0437 0.7989
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.016 0.0288
Schistosoma mansoni hypothetical protein 0.0284 0.1077 0.1964
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0003 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0088 0.0088
Trichomonas vaginalis aldo-keto reductase, putative 0.0039 0.0084 0.0214
Echinococcus multilocularis voltage gated potassium channel subunit 0.0039 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0221 0.0563
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0023 0.0181
Echinococcus multilocularis lysine specific demethylase 5A 0.0031 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0064 0.0187 0.0511
Echinococcus granulosus dnaJ subfamily B 0.0364 0.1403 0.2564
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0088 0.016
Echinococcus granulosus cpg binding protein 0.0099 0.0327 0.0597
Brugia malayi Ets-domain containing protein 0.0054 0.0145 0.0396
Brugia malayi acetyltransferase, GNAT family protein 0.044 0.171 0.469
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0094 0.024
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0093 0.0811
Loa Loa (eye worm) histone methyltransferase 0.0032 0.0056 0.0154
Onchocerca volvulus 0.0134 0.047 0.1193
Plasmodium falciparum ataxin-2 like protein, putative 0.0153 0.0546 1
Echinococcus multilocularis tar DNA binding protein 0.0178 0.0647 0.0646
Loa Loa (eye worm) hypothetical protein 0.0169 0.061 0.1672
Schistosoma mansoni tar DNA-binding protein 0.0178 0.0647 0.1177
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0012 0.0031
Echinococcus multilocularis Chromobox protein 3 0.0021 0.0012 0.0012
Schistosoma mansoni zinc finger protein 0.0065 0.0189 0.0341
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0382 0.0694
Onchocerca volvulus 0.0112 0.0382 0.0969
Schistosoma mansoni cpg binding protein 0.0089 0.0287 0.0519
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0026 0.0031 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0033
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0077 0.0239 0.2128
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0003 0.0006
Echinococcus granulosus fetal alzheimer antigen falz 0.0062 0.0176 0.0322
Trichomonas vaginalis aldo-keto reductase, putative 0.0039 0.0084 0.0214
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0069 0.0204 0.0204
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0382 0.3429
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0003 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0003 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0088 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0088 0.024
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Entamoeba histolytica alcohol dehydrogenase, putative 0.0039 0.0084 0.1732
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0134 0.047 0.1288
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0088 0.016
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0088 0.0156
Echinococcus granulosus lamin 0.0026 0.0034 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0088 0.024
Brugia malayi ecdysteroid receptor 0.004 0.0088 0.024
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.024
Brugia malayi MH2 domain containing protein 0.0021 0.0013 0.0036
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0012 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.0382 0.3429
Echinococcus granulosus Smad4 0.0048 0.0121 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0088 0.024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0033
Entamoeba histolytica hypothetical protein 0.0039 0.0085 0.1743
Trichomonas vaginalis CMGC family protein kinase 0.0077 0.0239 0.0608
Brugia malayi hypothetical protein 0.0039 0.0085 0.0231
Brugia malayi jmjC domain containing protein 0.0084 0.0267 0.0731
Brugia malayi beta-lactamase family protein 0.0112 0.0382 0.1048
Echinococcus granulosus geminin 0.0544 0.2133 0.3898
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0169 0.061 0.111
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0284 0.1077 0.1968
Schistosoma mansoni smad1 5 8 and 0.0048 0.0121 0.0216
Loa Loa (eye worm) hypothetical protein 0.0516 0.2018 0.5536
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0134 0.047 0.1199
Mycobacterium leprae Possible oxidoreductase 0.0039 0.0084 0.0468
Echinococcus multilocularis lamin dm0 0.0026 0.0034 0.0033
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0092 0.0169
Onchocerca volvulus Matrilysin homolog 0.0322 0.1233 0.314
Trypanosoma brucei protein kinase, putative 0.0077 0.0239 0.2128
Echinococcus granulosus zinc finger protein 0.0065 0.0189 0.0345
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.0382 0.1337
Loa Loa (eye worm) hypothetical protein 0.0177 0.0645 0.1768
Echinococcus multilocularis mitogen activated protein kinase 0.0077 0.0239 0.0238
Onchocerca volvulus Tyrosine kinase homolog 0.0166 0.06 0.1524
Schistosoma mansoni cpg binding protein 0.0099 0.0327 0.0592
Brugia malayi Matrixin family protein 0.0322 0.1233 0.338
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0056 0.0143
Onchocerca volvulus 0.0021 0.0012 0.0025
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0085 0.0154
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0127 0.0934
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0092 0.0164
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0012 0.0012
Loa Loa (eye worm) acetyltransferase 0.044 0.171 0.469
Schistosoma mansoni aldehyde dehydrogenase 0.0049 0.0127 0.0227
Brugia malayi PHD-finger family protein 0.0026 0.0031 0.0082
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0144 0.1273
Echinococcus multilocularis PHD finger protein rhinoceros 0.0026 0.0031 0.003
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0003 0.0003
Brugia malayi nuclear hormone receptor 0.0019 0.0003 0.0006
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.1262 0.5043 0.9217
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0088 0.0217
Schistosoma mansoni methyl-cpg binding protein mbd 0.0043 0.01 0.0178
Schistosoma mansoni Smad4 0.0048 0.0121 0.0216
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0003 0.0006
Echinococcus multilocularis microtubule associated protein 2 0.1368 0.5472 0.5472
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0134 0.047 0.4221
Echinococcus granulosus chromobox protein 2 0.0021 0.0012 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0153 0.0546 0.4907
Loa Loa (eye worm) TAR-binding protein 0.0178 0.0647 0.1772
Brugia malayi Ets-domain containing protein 0.0054 0.0145 0.0396
Loa Loa (eye worm) glutathione reductase 0.0046 0.0112 0.0307
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0073 0.0221 0.0556
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Brugia malayi hypothetical protein 0.0099 0.0326 0.0894
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0094 0.024
Leishmania major prostaglandin f synthase, putative 0.0134 0.047 0.4221
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Brugia malayi nuclear receptor NHR-67 0.0019 0.0003 0.0006
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0134 0.0468 0.6726
Leishmania major aldo-keto reductase-like protein 0.0134 0.047 0.4221
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0032
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0039 0.0084 0.117
Trichomonas vaginalis Heterochromatin protein, putative 0.0021 0.0012 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.005 0.0128
Schistosoma mansoni aldehyde dehydrogenase 0.0049 0.0127 0.0227
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0088 0.016
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0023 0.0151
Plasmodium vivax glutathione reductase, putative 0.0046 0.0112 0.2011
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0088 0.0217
Onchocerca volvulus 0.0451 0.1756 0.4476
Loa Loa (eye worm) hypothetical protein 0.0123 0.0423 0.116
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0077 0.0239 0.3406
Brugia malayi Matrixin family protein 0.0322 0.1233 0.338
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0033
Echinococcus granulosus Chromobox protein 3 0.0021 0.0012 0.0023
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.024
Loa Loa (eye worm) bromodomain containing protein 0.0055 0.0149 0.0408
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0003 0.0003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0088 0.024
Trypanosoma cruzi ISWI complex protein 0.0038 0.0082 0.0712
Giardia lamblia Aldose reductase 0.0134 0.047 1
Echinococcus granulosus transcription factor Dp 1 0.0031 0.0052 0.0096
Brugia malayi hypothetical protein 0.0451 0.1756 0.4817
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0032
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0284 0.1077 0.1968
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.0382 0.0382
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0382 0.0975
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0056 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0088 0.024
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0088 0.024
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0094 0.024
Echinococcus multilocularis chromobox protein 2 0.0021 0.0012 0.0012
Brugia malayi MH2 domain containing protein 0.0704 0.2779 0.7622
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0023 0.007
Schistosoma mansoni bromodomain containing protein 0.0026 0.0034 0.0057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0033
Schistosoma mansoni Smad4 0.0021 0.0013 0.002
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0056 0.0103
Plasmodium falciparum histone acetyltransferase GCN5 0.0117 0.0401 0.7328
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0039 0.0084 0.117
Loa Loa (eye worm) hypothetical protein 0.0172 0.0624 0.1711
Brugia malayi hypothetical protein 0.0021 0.0012 0.0031
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0012 0.0032
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Schistosoma mansoni glutaminase 0.0281 0.1066 0.1945
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0112 0.0382 0.1048
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0021 0.0012 0.0018
Brugia malayi CHD4 protein 0.0031 0.0052 0.0142
Leishmania major hypothetical protein, conserved 0.0153 0.0546 0.4907
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0012 0.0031
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0023 0.0151
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.035 0.1224
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0167 0.0603 0.1653
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.0035 0.0034
Schistosoma mansoni hypothetical protein 0.0131 0.0459 0.0834
Brugia malayi Latrophilin receptor protein 2 0.0131 0.0459 0.1258
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0134 0.047 0.1199
Mycobacterium ulcerans lipase LipD 0.0112 0.0382 0.2871
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0088 0.024
Entamoeba histolytica hypothetical protein 0.0021 0.0012 0.0199
Loa Loa (eye worm) oxidoreductase 0.0134 0.047 0.1288
Toxoplasma gondii aldehyde dehydrogenase 0.0049 0.0127 0.1785
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0193 0.0709 0.1291
Toxoplasma gondii aldose reductase, putative 0.0134 0.047 0.6756
Toxoplasma gondii PHD-finger domain-containing protein 0.0026 0.0031 0.0396
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0382 0.0694
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0021 0.0012 0.0134
Trichomonas vaginalis chromobox protein, putative 0.0129 0.0451 0.1151
Schistosoma mansoni ets-related 0.0164 0.0589 0.1073
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.035 0.2514
Trypanosoma cruzi aldo-keto reductase 0.0134 0.047 0.4221
Giardia lamblia Kinase, CMGC MAPK 0.0077 0.0239 0.5041
Brugia malayi Fli-1 protein 0.0164 0.0589 0.1616
Plasmodium falciparum heterochromatin protein 1 0.0021 0.0012 0.0171
Echinococcus multilocularis dnaJ subfamily B 0.0364 0.1403 0.1403
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0211 0.0783 0.1427
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0012 0.0199
Echinococcus multilocularis geminin 0.0544 0.2133 0.2133
Schistosoma mansoni amine GPCR 0.0242 0.0908 0.1655
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Onchocerca volvulus 0.0112 0.0382 0.0969
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0284 0.1077 0.2953
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0284 0.1077 0.1077
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0033
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0077 0.0239 0.0653
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0003 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0382 0.0975
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0866 0.3436 0.9426
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0084 0.0267 0.0267
Schistosoma mansoni aldo-keto reductase 0.0134 0.047 0.0855
Loa Loa (eye worm) hypothetical protein 0.0064 0.0187 0.0511
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0088 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0088 0.024
Loa Loa (eye worm) hypothetical protein 0.0026 0.0031 0.0082
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0054 0.0144 0.0394
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0077 0.0239 0.0608
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.024
Mycobacterium ulcerans beta-lactamase 0.0112 0.0382 0.2871
Echinococcus granulosus aldo keto reductase 0.0134 0.047 0.0859
Brugia malayi ecdysone receptor 0.0019 0.0003 0.0006
Onchocerca volvulus 0.0322 0.1233 0.314
Loa Loa (eye worm) oxidoreductase 0.0134 0.047 0.1288
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0003 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1109 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0088 0.024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0088 0.0156
Schistosoma mansoni aldo-keto reductase 0.0134 0.047 0.0855
Echinococcus multilocularis Smad4 0.0048 0.0121 0.0121
Onchocerca volvulus Matrilysin homolog 0.0861 0.3416 0.8713
Echinococcus granulosus intermediate filament protein 0.0026 0.0034 0.0061
Entamoeba histolytica aldose reductase, putative 0.0134 0.047 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0012 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0088 0.024
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0003 0.0003
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0003 0.0005
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0023 0.0181
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0012 0.0021
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0088 0.024
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0112 0.2011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0437 0.0794
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.1262 0.5043 0.5043
Trichomonas vaginalis glutaminase, putative 0.0281 0.1066 0.272
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0049 0.0127 0.1116
Loa Loa (eye worm) MH2 domain-containing protein 0.0048 0.0121 0.033
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0039 0.0084 0.149
Loa Loa (eye worm) hypothetical protein 0.0073 0.0221 0.0604
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0091
Echinococcus multilocularis GPCR, family 2 0.0131 0.0459 0.0459
Echinococcus multilocularis Protein lozenge 0.0057 0.0156 0.0156
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0021 0.0012 0.0023
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.0382 0.1048
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0147 0.0523 0.0951
Brugia malayi jmjC domain containing protein 0.0041 0.0092 0.0252
Brugia malayi TAR-binding protein 0.0178 0.0647 0.1772
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0088 0.024
Echinococcus granulosus lamin dm0 0.0026 0.0034 0.0061
Brugia malayi CXXC zinc finger family protein 0.0089 0.0287 0.0785
Schistosoma mansoni chromobox protein 0.0021 0.0012 0.0018
Schistosoma mansoni hypothetical protein 0.0401 0.1554 0.2836
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0397 0.1391
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0034 0.0091
Loa Loa (eye worm) MH1 domain-containing protein 0.0048 0.0121 0.033
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0031 0.0052 0.0052
Leishmania major hypothetical protein, conserved 0.0112 0.0382 0.3429
Trypanosoma cruzi aldo/keto reductase, putative 0.0134 0.047 0.4221
Brugia malayi SET domain containing protein 0.0028 0.0039 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0382 0.3429
Brugia malayi Muscleblind-like protein 0.0172 0.0624 0.1711
Echinococcus multilocularis Chromo domain 0.0021 0.0012 0.0012
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0003 0.0003
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0088 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0084 0.0214
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0078 0.0243 0.0613
Echinococcus granulosus peregrin 0.0042 0.0098 0.0178
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0437 0.6274
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0094 0.024
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.0486 0.4368
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0034 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0032
Echinococcus granulosus GPCR family 2 0.0131 0.0459 0.0839
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Plasmodium vivax aldehyde reductase, putative 0.0039 0.0084 0.149
Trichomonas vaginalis chromobox protein, putative 0.0021 0.0012 0.0032
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0119 0.041 0.075
Plasmodium falciparum ataxin-2 like protein, putative 0.0153 0.0546 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0088 0.024
Echinococcus multilocularis muscleblind protein 0.0172 0.0624 0.0624
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0055 0.015 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0056 0.0143
Entamoeba histolytica hypothetical protein 0.0021 0.0012 0.0199
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0088 0.016
Mycobacterium tuberculosis Conserved protein 0.0039 0.0084 0.0285
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Brugia malayi NADH-dependent xylose reductase 0.0039 0.0084 0.0229
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0134 0.0468 0.8565
Echinococcus multilocularis aldo keto reductase 0.0134 0.047 0.047
Mycobacterium ulcerans hydrolase 0.0345 0.1324 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0153 0.0546 0.1496
Mycobacterium ulcerans hypothetical protein 0.0154 0.055 0.4136
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0058 0.016 0.0438
Schistosoma mansoni pol-related 0.0134 0.047 0.0855
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0221 0.0563
Brugia malayi chromobox protein homolog 3 0.0073 0.0221 0.0604
Brugia malayi MH1 domain containing protein 0.0048 0.0121 0.033
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0003 0.0006
Brugia malayi nuclear receptor NHR-88 0.004 0.0088 0.024
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0649 0.2557 0.467
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0054 0.0144 0.0394
Echinococcus granulosus histone acetyltransferase KAT2B 0.0134 0.0468 0.0855
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Giardia lamblia PHD finger protein 15 0.0026 0.0031 0.0586
Mycobacterium tuberculosis Probable reductase 0.0104 0.035 0.1224
Mycobacterium ulcerans hypothetical protein 0.0039 0.0084 0.0612
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0062 0.0176 0.0317
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0023 0.0062
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0034 0.0091
Echinococcus granulosus potassium voltage gated channel protein 0.0058 0.016 0.0293
Schistosoma mansoni nuclear hormone receptor 0.004 0.0088 0.0156
Loa Loa (eye worm) RNA binding protein 0.0178 0.0647 0.1772
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Mycobacterium ulcerans oxidoreductase 0.0134 0.047 0.3534
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0093 0.0811
Echinococcus granulosus TGF beta signal transducer SmadC 0.0048 0.0121 0.0221
Schistosoma mansoni smad 0.0021 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0091
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0021 0.0012 0.0134
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0012 0.0199
Schistosoma mansoni tar DNA-binding protein 0.0178 0.0647 0.1177
Mycobacterium tuberculosis Probable oxidoreductase 0.0134 0.047 0.1647
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0131 0.0459 0.0459
Schistosoma mansoni intermediate filament proteins 0.0026 0.0034 0.0056
Echinococcus multilocularis aldehyde reductase 0.0095 0.0313 0.0313
Schistosoma mansoni chromobox protein 0.0129 0.0451 0.082
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0085 0.015
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0048 0.0121 0.0216
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0077 0.0239 0.2128
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0309
Schistosoma mansoni hypothetical protein 0.0544 0.2133 0.3895
Trypanosoma brucei trypanothione reductase 0.0046 0.0112 0.0987
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0134 0.047 0.3435
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0284 0.1077 0.1964
Echinococcus granulosus chromobox protein 1 0.0129 0.0451 0.0824
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0032
Brugia malayi glutathione reductase 0.0046 0.0112 0.0307
Schistosoma mansoni hypothetical protein 0.0131 0.0459 0.0834
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0092 0.0252
Loa Loa (eye worm) hypothetical protein 0.0044 0.0105 0.0286
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0054 0.0144 0.0258
Trichomonas vaginalis aldo-keto reductase, putative 0.0039 0.0084 0.0214
Trichomonas vaginalis chromobox protein, putative 0.0021 0.0012 0.0032
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0021 0.0012 0.0171
Brugia malayi nuclear hormone receptor 0.004 0.0088 0.024
Loa Loa (eye worm) oxidoreductase 0.0134 0.047 0.1288
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.024
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0093 0.0811
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0023 0.0151
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0088 0.024
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0023 0.0151
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0003 0.0005
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.1109 1
Schistosoma mansoni Smad4 0.0021 0.0013 0.002
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0088 0.024
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0049 0.0127 0.0435
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0023 0.0428
Toxoplasma gondii LsmAD domain-containing protein 0.0153 0.0546 0.7853
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Schistosoma mansoni polycystin 1-related 0.0173 0.0629 0.1145
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0035 0.0068 0.012
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0486 0.4368
Mycobacterium tuberculosis Conserved protein 0.0112 0.0382 0.1337
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0003 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0094 0.024
Brugia malayi Matrixin family protein 0.0322 0.1233 0.338
Loa Loa (eye worm) matrix metalloproteinase 0.0322 0.1233 0.338
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0023 0.0062
Loa Loa (eye worm) oxidoreductase 0.0134 0.047 0.1288
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0077 0.0239 0.2128
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0012 0.0171
Trypanosoma cruzi ISWI complex protein 0.0038 0.0082 0.0712
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0023 0.0428
Brugia malayi Immunoglobulin I-set domain containing protein 0.0167 0.0603 0.1653
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0039 0.0084 0.0229
Trypanosoma brucei ISWI complex protein 0.0038 0.0082 0.0712
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0023 0.0062
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.0382 0.1337
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0088 0.0088
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0054 0.0144 0.1273
Brugia malayi hypothetical protein 0.0021 0.0012 0.0033
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0088 0.0156
Schistosoma mansoni tar DNA-binding protein 0.0178 0.0647 0.1177
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0131 0.0459 0.1258
Loa Loa (eye worm) hypothetical protein 0.004 0.0088 0.024
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.035 0.1224
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0088 0.016
Trichomonas vaginalis set domain proteins, putative 0.0985 0.392 1
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0243 0.062
Loa Loa (eye worm) PHD-finger family protein 0.0026 0.0031 0.0082
Onchocerca volvulus 0.0026 0.0034 0.0079
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0023 0.0151
Schistosoma mansoni hypothetical protein 0.0038 0.0082 0.0145
Echinococcus granulosus hypothetical protein 0.0134 0.047 0.0859
Trichomonas vaginalis aldo/keto reductase, putative 0.0134 0.047 0.1199
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0284 0.1077 0.1077
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0382 0.0975
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0094 0.024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0112 0.0987
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0054 0.0145 0.0396
Brugia malayi MH2 domain containing protein 0.0048 0.0121 0.033
Loa Loa (eye worm) hypothetical protein 0.0096 0.0316 0.0866
Schistosoma mansoni chromobox protein 0.0021 0.0012 0.0018
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0062
Echinococcus granulosus tar DNA binding protein 0.0178 0.0647 0.1181
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0134 0.047 0.1288
Schistosoma mansoni eyes absent homolog 0.0064 0.0187 0.0337
Plasmodium falciparum glutathione reductase 0.0046 0.0112 0.2011
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0135 0.0344
Echinococcus multilocularis cpg binding protein 0.0099 0.0327 0.0326
Brugia malayi Pre-SET motif family protein 0.0866 0.3436 0.9426
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Loa Loa (eye worm) hypothetical protein 0.0284 0.1077 0.2953
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0085 0.0084
Schistosoma mansoni thyroid hormone receptor 0.004 0.0088 0.0156
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0021 0.0013 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0094 0.024
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Brugia malayi nuclear receptor RXR 0.0019 0.0003 0.0006
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.1109 1
Echinococcus granulosus microtubule associated protein 2 0.1368 0.5472 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.044 0.171 0.3122
Echinococcus multilocularis jumonji domain containing protein 0.0036 0.0071 0.0071
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0012 0.0171
Onchocerca volvulus 0.0112 0.0382 0.0969
Loa Loa (eye worm) hypothetical protein 0.0112 0.0382 0.1048
Onchocerca volvulus 0.0134 0.047 0.1193
Loa Loa (eye worm) beta-lactamase 0.0112 0.0382 0.1048
Brugia malayi Calcitonin receptor-like protein seb-1 0.0415 0.1609 0.4414
Mycobacterium leprae PROBABLE HYDROLASE 0.0345 0.1324 1
Mycobacterium tuberculosis Conserved protein 0.0112 0.0382 0.1337
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0178 0.0647 0.1772
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0039 0.0084 0.0229
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0054 0.0144 0.0263
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0033
Brugia malayi Bromodomain containing protein 0.0107 0.0359 0.0983
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0134 0.047 0.1288
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0077 0.0239 0.2128
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0088 0.016
Brugia malayi F/Y-rich N-terminus family protein 0.0045 0.0108 0.0296
Leishmania major trypanothione reductase 0.0046 0.0112 0.0987
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0088 0.0156
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0003 0.5
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0088 0.024
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0088 0.024
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0049 0.0127 0.0231
Brugia malayi RNA recognition motif domain containing protein 0.0178 0.0647 0.1772
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Brugia malayi PHD-finger family protein 0.0078 0.0243 0.0666
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0415 0.1609 0.4414
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0088 0.0156
Mycobacterium leprae conserved hypothetical protein 0.0112 0.0382 0.2761
Schistosoma mansoni hypothetical protein 0.0039 0.0085 0.015
Plasmodium vivax SET domain containing protein 0.0023 0.002 0.0312
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0084 0.0267 0.0488
Brugia malayi Pre-SET motif family protein 0.0126 0.0437 0.1197
Trichomonas vaginalis aldo/keto reductase, putative 0.0134 0.047 0.1199
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Echinococcus granulosus mothers against decapentaplegic 6 0.0021 0.0013 0.0024
Loa Loa (eye worm) hypothetical protein 0.0112 0.0382 0.1048
Brugia malayi hypothetical protein 0.0064 0.0187 0.0511
Loa Loa (eye worm) nuclear factor I 0.0027 0.0034 0.0092
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0039 0.0084 0.0214
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0134 0.047 0.1288
Echinococcus granulosus muscleblind protein 0.0172 0.0624 0.1141
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0088 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0088 0.024
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0003 0.0006
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0003 0.0003
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0039 0.0084 0.0153
Brugia malayi conserved hypotetical protein 0.0019 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0134 0.047 0.1288
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Brugia malayi Thioredoxin reductase 0.0046 0.0112 0.0307
Brugia malayi intermediate filament protein 0.0026 0.0034 0.0091
Echinococcus multilocularis chromobox protein 1 0.0129 0.0451 0.0451
Entamoeba histolytica hypothetical protein 0.0039 0.0085 0.1743
Onchocerca volvulus Matrix metalloproteinase homolog 0.0667 0.263 0.6707
Brugia malayi Smad1 0.0048 0.0121 0.033
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0021 0.0012 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0382 0.0975
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.0035 0.0063
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0134 0.047 0.0859
Brugia malayi M-phase phosphoprotein, mpp8 0.0021 0.0012 0.0033
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0088 0.016
Schistosoma mansoni hypothetical protein 0.0069 0.0204 0.0369
Trichomonas vaginalis CMGC family protein kinase 0.0077 0.0239 0.0608
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.0382 0.1337
Echinococcus multilocularis aldo keto reductase 0.0134 0.047 0.047
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0023 0.0428
Plasmodium falciparum aldo-keto reductase, putative 0.0039 0.0084 0.149
Echinococcus multilocularis mothers against decapentaplegic 2 0.0021 0.0013 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0127 0.0934
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0088 0.024
Echinococcus multilocularis GA binding protein alpha chain 0.0054 0.0145 0.0145
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0088 0.0156
Echinococcus multilocularis mitogen activated protein kinase 3 0.0077 0.0239 0.0238
Trypanosoma cruzi PAB1-binding protein , putative 0.0153 0.0546 0.4907
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.009 0.0292 0.0291
Loa Loa (eye worm) matrixin family protein 0.0917 0.3645 1
Echinococcus granulosus voltage gated potassium channel subunit 0.0039 0.0084 0.0153
Brugia malayi Valyl-tRNA synthetase 0.0021 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Echinococcus granulosus mothers against decapentaplegic 5 0.0048 0.0121 0.0221
Brugia malayi tailless protein 0.0019 0.0003 0.0006
Echinococcus granulosus aldo keto reductase 0.0134 0.047 0.0859
Onchocerca volvulus 0.0039 0.0084 0.0208
Echinococcus granulosus smad 0.0048 0.0121 0.0221
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0113 0.0383 0.1051
Echinococcus multilocularis transcription factor Dp 1 0.0031 0.0052 0.0052
Echinococcus granulosus mitogen activated protein kinase 0.0077 0.0239 0.0436
Brugia malayi latrophilin 2 splice variant baaae 0.0284 0.1077 0.2953
Echinococcus granulosus PHD finger protein rhinoceros 0.0026 0.0031 0.0056
Echinococcus multilocularis aldo keto reductase 0.0134 0.047 0.047
Trichomonas vaginalis chromobox protein, putative 0.0021 0.0012 0.0032
Entamoeba histolytica acetyltransferase, GNAT family 0.0117 0.0401 0.8517
Loa Loa (eye worm) runx1 0.0057 0.0156 0.0427
Echinococcus multilocularis lamin 0.0026 0.0034 0.0033
Schistosoma mansoni smad 0.0048 0.0121 0.0216
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0088 0.0156
Loa Loa (eye worm) oxidoreductase 0.0134 0.047 0.1288
Brugia malayi MH1 domain containing protein 0.0048 0.0121 0.033
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0382 0.0975
Schistosoma mansoni hypothetical protein 0.0364 0.1403 0.256
Loa Loa (eye worm) hypothetical protein 0.0322 0.1233 0.338
Brugia malayi Protein cec-1. 0.0021 0.0012 0.0033
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0397 0.1391
Entamoeba histolytica aldose reductase, putative 0.0134 0.047 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0284 0.1077 0.1964
Schistosoma mansoni smad1 5 8 and 0.0048 0.0121 0.0216
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0088 0.024
Echinococcus multilocularis smad 0.0048 0.0121 0.0121
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0486 0.4368
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0382 0.6987
Echinococcus granulosus chromobox protein 1 0.0129 0.0451 0.0824
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0012 0.0031
Trichomonas vaginalis hypothetical protein 0.0021 0.0012 0.0032
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0516 0.2018 0.3686
Schistosoma mansoni chromobox protein 0.0129 0.0451 0.082
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0012 0.0199
Echinococcus granulosus aldo keto reductase 0.0134 0.047 0.0859
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0093 0.0811
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0092
Brugia malayi hypothetical protein 0.0019 0.0003 0.0006
Mycobacterium ulcerans glutaminase 0.0281 0.1066 0.8048
Toxoplasma gondii hypothetical protein 0.0047 0.0117 0.1652
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0134 0.047 0.1199
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0127 0.0934
Loa Loa (eye worm) hypothetical protein 0.0131 0.0459 0.1258
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.035 0.1224
Echinococcus granulosus mothers against decapentaplegic 2 0.0021 0.0013 0.0024
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0112 0.0385
Onchocerca volvulus 0.0057 0.0157 0.0394
Entamoeba histolytica alcohol dehydrogenase, putative 0.0039 0.0084 0.1732
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0049 0.0127 0.0126
Echinococcus multilocularis mothers against decapentaplegic 5 0.0048 0.0121 0.0121
Echinococcus multilocularis chromobox protein 1 0.0129 0.0451 0.0451
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0243 0.062
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0144 0.1273
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0118 0.0405 0.0735
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0023 0.0181
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Trypanosoma brucei aldo/keto reductase, putative 0.0039 0.0084 0.0731
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0077 0.0239 0.2128
Mycobacterium tuberculosis Conserved protein 0.0112 0.0382 0.1337
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0001
Brugia malayi steroid hormone receptor 0.004 0.0088 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0012 0.0032
Echinococcus granulosus FTZ F1 alpha 0.004 0.0088 0.016
Brugia malayi Heterochromatin protein 1 0.0129 0.0451 0.1236
Brugia malayi Matrixin family protein 0.0322 0.1233 0.338
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.035 0.1224
Plasmodium falciparum thioredoxin reductase 0.0046 0.0112 0.2011
Schistosoma mansoni lozenge 0.0057 0.0156 0.0281
Echinococcus multilocularis potassium voltage gated channel protein 0.0058 0.016 0.016
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0021 0.0012 0.0033
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0003 0.0007
Trichomonas vaginalis esterase, putative 0.0112 0.0382 0.0975
Loa Loa (eye worm) latrophilin receptor protein 2 0.0131 0.0459 0.1258
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.0382 0.1337
Brugia malayi Bromodomain containing protein 0.0204 0.0752 0.2061
Schistosoma mansoni methyl-cpg binding protein mbd 0.0043 0.01 0.0178
Mycobacterium leprae Probable lipase LipE 0.0112 0.0382 0.2761
Brugia malayi hypothetical protein 0.0153 0.0546 0.1496
Brugia malayi Associated with TFs and helicases family protein 0.0021 0.0012 0.0033
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0165 0.0596 0.109
Trypanosoma brucei prostaglandin f synthase 0.0134 0.047 0.4221
Schistosoma mansoni bromodomain containing protein 0.0174 0.0633 0.1152
Loa Loa (eye worm) hypothetical protein 0.0415 0.1609 0.4414
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0088 0.0088
Mycobacterium ulcerans hypothetical protein 0.0024 0.0023 0.0151
Schistosoma mansoni hypothetical protein 0.0026 0.0031 0.0051
Loa Loa (eye worm) glutaminase 2 0.0281 0.1066 0.2924
Loa Loa (eye worm) hypothetical protein 0.0057 0.0157 0.043
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.055 0.1927
Echinococcus granulosus histone acetyltransferase KAT2B 0.0422 0.1636 0.2991
Loa Loa (eye worm) hypothetical protein 0.0322 0.1233 0.338
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0112 0.0205
Loa Loa (eye worm) hypothetical protein 0.0112 0.0382 0.1048
Schistosoma mansoni hypothetical protein 0.0021 0.0012 0.0018
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0027 0.0035 0.0034
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Entamoeba histolytica hypothetical protein 0.0039 0.0085 0.1743
Loa Loa (eye worm) Smad1 0.0048 0.0121 0.033
Schistosoma mansoni thyroid hormone receptor 0.004 0.0088 0.0156
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.0382 0.1337
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0134 0.0468 0.6726
Schistosoma mansoni zinc finger protein 0.0038 0.0082 0.0145
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0023 0.007
Loa Loa (eye worm) hypothetical protein 0.0451 0.1756 0.4817
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0021
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0001
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0134 0.047 0.4221
Brugia malayi RNA binding protein 0.0178 0.0647 0.1772
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0129 0.114
Onchocerca volvulus 0.0021 0.0012 0.0025
Echinococcus granulosus aldehyde reductase 0.0095 0.0313 0.0571
Echinococcus granulosus GA binding protein alpha chain 0.0054 0.0145 0.0265
Onchocerca volvulus 0.0026 0.0034 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0023 0.0151
Trypanosoma brucei PAB1-binding protein , putative 0.0153 0.0546 0.4907
Loa Loa (eye worm) CHromoDomain protein family member 0.0031 0.0052 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0135 0.0344
Brugia malayi hypothetical protein 0.0021 0.0012 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0178 0.0647 0.1177
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0031 0.0052 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0006
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0058 0.016 0.0293
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0012 0.0017
Echinococcus granulosus mixed lineage leukemia protein mll 0.0027 0.0035 0.0063
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0077 0.0239 0.2128
Onchocerca volvulus Alhambra homolog 0.0026 0.0031 0.0071
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0062 0.0176 0.0176
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.0382 0.2871
Schistosoma mansoni voltage-gated potassium channel 0.0058 0.016 0.0288
Entamoeba histolytica hypothetical protein 0.0021 0.0012 0.0199
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.0382 0.2871
Plasmodium falciparum aldehyde reductase, putative 0.0039 0.0084 0.149
Brugia malayi MH1 domain containing protein 0.0027 0.0034 0.0092
Loa Loa (eye worm) jmjC domain-containing protein 0.0053 0.0141 0.0386
Trypanosoma brucei aldo-keto reductase, putative 0.0134 0.047 0.4221
Schistosoma mansoni cpg binding protein 0.0099 0.0327 0.0592
Schistosoma mansoni hypothetical protein 0.0131 0.0459 0.0834
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0134 0.047 0.047
Loa Loa (eye worm) CXXC zinc finger family protein 0.0089 0.0287 0.0785
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0088 0.0217
Trichomonas vaginalis bromodomain-containing protein, putative 0.0134 0.0468 0.1194
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0397 0.1391
Schistosoma mansoni gabp alpha 0.0054 0.0145 0.026
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0165 0.0596 0.0596
Toxoplasma gondii aldo-keto reductase 0.0039 0.0084 0.117
Schistosoma mansoni potassium channel beta 0.0039 0.0084 0.0149
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.009 0.0292 0.0533
Loa Loa (eye worm) PHD-finger family protein 0.0052 0.0136 0.0372
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.044 0.171 0.171
Plasmodium vivax heterochromatin protein 1, putative 0.0021 0.0012 0.0171
Trichomonas vaginalis aldo-keto reductase, putative 0.0134 0.047 0.1199
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0021 0.0012 0.0018
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0134 0.0468 0.1194
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0062
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0112 0.0307

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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