Detailed information for compound 685042

Basic information

Technical information
  • TDR Targets ID: 685042
  • Name: N-[4-(1,3-benzothiazol-2-yl)phenyl]-3-methyls ulfonylbenzamide
  • MW: 408.493 | Formula: C21H16N2O3S2
  • H donors: 1 H acceptors: 4 LogP: 4.11 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cccc(c1)S(=O)(=O)C)Nc1ccc(cc1)c1nc2c(s1)cccc2
  • InChi: 1S/C21H16N2O3S2/c1-28(25,26)17-6-4-5-15(13-17)20(24)22-16-11-9-14(10-12-16)21-23-18-7-2-3-8-19(18)27-21/h2-13H,1H3,(H,22,24)
  • InChiKey: NESCIJXAXHJTPQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-(1,3-benzothiazol-2-yl)phenyl]-3-methylsulfonyl-benzamide
  • N-[4-(1,3-benzothiazol-2-yl)phenyl]-3-mesyl-benzamide
  • T5994302
  • ZINC04517897

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei glucosidase, putative 0.0038 0.029 0.0745
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.029 0.212
Schistosoma mansoni hypothetical protein 0.044 0.56 0.56
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.1727 0.4443
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0026 0.0136 0.0349
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0088 0.0225
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.0031 0.0081
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0636 0.4962
Brugia malayi RNA recognition motif domain containing protein 0.0663 0.8541 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0031 0.0081
Trypanosoma brucei unspecified product 0.0043 0.0351 0.0903
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0077 0.008
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0088 0.1492
Schistosoma mansoni DNA polymerase eta 0.0043 0.0351 0.0351
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0636 0.1635
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0167 0.0148
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0118 0.0304
Brugia malayi Metabotropic glutamate receptor precursor. 0.0047 0.0402 0.0462
Echinococcus multilocularis potassium channel subfamily K 8 0.0026 0.0136 0.0111
Loa Loa (eye worm) hypothetical protein 0.0057 0.0538 0.0546
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0351 0.1619
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.125 0.3999
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0136 0.0342
Schistosoma mansoni twik family of potassium channels-related 0.0026 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Trichomonas vaginalis set domain proteins, putative 0.0249 0.3077 1
Echinococcus multilocularis snurportin 1 0.0331 0.4162 0.4147
Brugia malayi jmjC domain containing protein 0.0039 0.0297 0.0338
Plasmodium vivax potassium channel, putative 0.0026 0.0136 0.0767
Loa Loa (eye worm) TWK-7 protein 0.0026 0.0136 0.0115
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0026 0.0136 0.0149
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0088 0.0225
Leishmania major mitochondrial DNA polymerase beta 0.0311 0.3888 1
Toxoplasma gondii ion channel protein 0.0026 0.0136 0.0854
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0026 0.0136 0.0149
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.013 0.2934
Loa Loa (eye worm) hypothetical protein 0.0111 0.125 0.1308
Loa Loa (eye worm) hypothetical protein 0.0029 0.0167 0.0148
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0172 0.2057 0.2172
Schistosoma mansoni eyes absent homolog 0.0097 0.1064 0.1064
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0026 0.0136 0.0149
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0026 0.0136 0.0149
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0351 0.0903
Echinococcus granulosus small conductance calcium activated potassium 0.0725 0.9367 0.9365
Schistosoma mansoni calcium-activated potassium channel 0.0725 0.9367 0.9367
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0196 0.0172
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0123 0.0753
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0031 0.0031
Echinococcus granulosus peregrin 0.0035 0.025 0.0226
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.125 0.6338
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Brugia malayi Glycosyl hydrolases family 31 protein 0.0172 0.2057 0.2401
Trichomonas vaginalis ran, putative 0.0023 0.0088 0.0184
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Loa Loa (eye worm) TAR-binding protein 0.0663 0.8541 0.9116
Brugia malayi mbt repeat family protein 0.005 0.0447 0.0514
Leishmania major hypothetical protein, conserved 0.0111 0.125 0.3214
Schistosoma mansoni tar DNA-binding protein 0.0663 0.8541 0.8541
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.029 0.028
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.1879 0.2193
Brugia malayi hypothetical protein 0.0026 0.0136 0.0149
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.0031 0.0081
Schistosoma mansoni ap endonuclease 0.0019 0.0043 0.0043
Leishmania major GTP-binding protein, putative 0.0023 0.0088 0.0225
Schistosoma mansoni tar DNA-binding protein 0.0663 0.8541 0.8541
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0658 0.5144
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.0351 0.0339
Leishmania major ion transport protein-like protein 0.0026 0.0136 0.0349
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0123 0.0099
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0039 0.0302 0.0278
Echinococcus multilocularis small conductance calcium activated potassium 0.0725 0.9367 0.9365
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.013 0.0813
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.125 0.125
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.0031 0.0081
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0538 0.0515
Loa Loa (eye worm) hypothetical protein 0.0022 0.0076 0.0051
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0196 0.1348
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0026 0.0136 0.0149
Plasmodium falciparum potassium channel 0.0026 0.0136 0.3102
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0447 0.0448
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0075 0.005
Leishmania major hypothetical protein, conserved 0.0026 0.0136 0.0349
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.0031 0.0007
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0032 0.0082
Loa Loa (eye worm) hypothetical protein 0.0051 0.0457 0.0459
Echinococcus granulosus potassium channel subfamily K 8 0.0026 0.0136 0.0111
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.1947 0.2093
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0636 0.0652
Echinococcus granulosus lysosomal alpha glucosidase 0.0172 0.2057 0.2037
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.125 0.125
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0284 0.3535 0.3519
Loa Loa (eye worm) hypothetical protein 0.0031 0.0196 0.0179
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0425 0.0401
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.125 0.1327
Onchocerca volvulus 0.0032 0.0208 0.0248
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0042 0.0344 0.0394
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.125 0.3214
Brugia malayi mbt repeat family protein 0.005 0.0447 0.0514
Echinococcus granulosus zinc finger protein 0.0026 0.0134 0.0109
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.125 0.1228
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0636 0.3114
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.029 0.0848
Echinococcus multilocularis zinc finger protein 0.0026 0.0134 0.0109
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0708 0.9138 1
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.1483 0.1558
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0026 0.0136 0.0349
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0208 0.0184
Brugia malayi MH2 domain containing protein 0.0128 0.1483 0.1728
Loa Loa (eye worm) RNA binding protein 0.0663 0.8541 0.9116
Loa Loa (eye worm) hypothetical protein 0.0111 0.125 0.1308
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0031 0.0003
Brugia malayi Importin beta-1 subunit 0.0031 0.0196 0.022
Loa Loa (eye worm) hypothetical protein 0.0097 0.1064 0.1109
Mycobacterium tuberculosis Conserved protein 0.0111 0.125 0.1327
Onchocerca volvulus 0.0031 0.0194 0.0199
Loa Loa (eye worm) hypothetical protein 0.0111 0.125 0.1308
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0447 0.0447
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0297 0.0273
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.125 0.1327
Loa Loa (eye worm) hypothetical protein 0.005 0.0447 0.0448
Schistosoma mansoni hypothetical protein 0.0033 0.0227 0.0227
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0057 0.0545 0.0521
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0043 0.0111
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.0447 0.0424
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0351 0.0402
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.1727 0.4443
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0284 0.3535 0.3519
Entamoeba histolytica deoxycytidyl transferase, putative 0.0043 0.0351 1
Leishmania major DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Mycobacterium ulcerans hypothetical protein 0.0164 0.1947 1
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0572 0.0583
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0208 0.1453
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0026 0.0136 0.0149
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus granulosus dna polymerase kappa 0.0043 0.0351 0.0327
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0489 0.1257
Schistosoma mansoni ap endonuclease 0.0019 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.005 0.0447 0.0448
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.125 0.1327
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0447 0.0447
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.029 0.0745
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0084 0.0059
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0043 0.0351 0.0327
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Echinococcus granulosus cpg binding protein 0.0035 0.0244 0.022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0284 0.3535 0.4133
Onchocerca volvulus 0.0111 0.125 0.3787
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0167 0.1026
Mycobacterium ulcerans ion transport protein 0.0026 0.0136 0.0486
Loa Loa (eye worm) hypothetical protein 0.0075 0.0776 0.08
Schistosoma mansoni hypothetical protein 0.0308 0.3856 0.3856
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.125 0.1228
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.125 0.3999
Schistosoma mansoni hypothetical protein 0.0719 0.9289 0.9289
Brugia malayi RNA binding protein 0.0663 0.8541 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.125 0.3999
Toxoplasma gondii ion channel protein 0.0026 0.0136 0.0854
Onchocerca volvulus 0.005 0.0447 0.1058
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.125 0.3214
Schistosoma mansoni tar DNA-binding protein 0.0663 0.8541 0.8541
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0341 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.029 0.0848
Mycobacterium ulcerans lipase LipD 0.0111 0.125 0.6338
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0194 0.0177
Leishmania major DNA polymerase eta, putative 0.0043 0.0351 0.0903
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0636 0.0636
Mycobacterium ulcerans transmembrane cation transporter 0.0026 0.0136 0.0486
Schistosoma mansoni hypothetical protein 0.0026 0.0136 0.0136
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0447 0.0423
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.1483 0.1558
Schistosoma mansoni twik family of potassium channels-related 0.0026 0.0136 0.0136
Schistosoma mansoni microtubule-associated protein tau 0.0773 1 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0025 0.0025
Echinococcus multilocularis twik family of potassium channels 0.0026 0.0136 0.0111
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.0031 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0284 0.3535 0.3535
Loa Loa (eye worm) TWK-28 protein 0.0026 0.0136 0.0115
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0032 0.0082
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.029 0.0848
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0351 0.105
Schistosoma mansoni hypothetical protein 0.0719 0.9289 0.9289
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0088 0.0063
Schistosoma mansoni importin beta-1 0.0031 0.0196 0.0196
Echinococcus multilocularis dnaJ subfamily B 0.044 0.56 0.5589
Loa Loa (eye worm) hypothetical protein 0.0043 0.0351 0.0346
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.1033 0.1011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0425 0.1292
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0088 0.046
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.029 0.0848
Schistosoma mansoni twik family of potassium channels-related 0.0026 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Onchocerca volvulus Alhambra homolog 0.0029 0.0167 0.0106
Trypanosoma brucei calcium-activated potassium channel, putative 0.0026 0.0136 0.0349
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.029 0.0266
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0289 0.0265
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.0031 0.0081
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0043 0.0016
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.0031 0.0007
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.0031 0.0081
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.0031 0.0081
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0363 0.0933
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.029 0.0848
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0043 0.0018
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0043 0.036
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0125 0.01
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0043 0.0111
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.1879 0.1859
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.125 0.6338
Mycobacterium leprae Probable lipase LipE 0.0111 0.125 0.5
Brugia malayi beta-lactamase family protein 0.0111 0.125 0.1455
Onchocerca volvulus 0.0099 0.1099 0.3276
Entamoeba histolytica hypothetical protein 0.0025 0.0118 0.2712
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0118 0.0285
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0043 0.5
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0284 0.3535 0.3519
Trypanosoma brucei unspecified product 0.003 0.0176 0.0452
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0026 0.0136 0.3254
Schistosoma mansoni hypothetical protein 0.0331 0.4162 0.4162
Echinococcus granulosus twik family of potassium channels 0.0026 0.0136 0.0111
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0247 0.0223
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0043 0.036
Echinococcus granulosus calcium activated potassium channel variant 0.0026 0.0136 0.0111
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.0351 0.0903
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0663 0.8541 0.9116
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0026 0.0136 0.0349
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0043 0.0351 0.0351
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0447 0.0447
Loa Loa (eye worm) hypothetical protein 0.0041 0.0323 0.0316
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.029 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0123 0.0301
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0026 0.0136 0.0149
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.1727 0.4443
Echinococcus multilocularis microtubule associated protein 2 0.0773 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Onchocerca volvulus 0.0249 0.3077 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.125 0.1327
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.125 0.1327
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.0031 0.0081
Schistosoma mansoni cpg binding protein 0.0035 0.0244 0.0244
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0176 0.0452
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0026 0.0136 0.0349
Brugia malayi PHD-finger family protein 0.0029 0.0167 0.0186
Echinococcus granulosus tar DNA binding protein 0.0663 0.8541 0.8538
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.125 0.1308
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0136 0.0342
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0297 0.0288
Toxoplasma gondii exonuclease III APE 0.0019 0.0043 0.0094
Brugia malayi TAR-binding protein 0.0663 0.8541 1
Echinococcus granulosus twik family of potassium channels 0.0026 0.0136 0.0111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0284 0.3535 0.3519
Echinococcus granulosus jumonji domain containing protein 0.004 0.0316 0.0292
Schistosoma mansoni calcium-activated potassium channel 0.0441 0.5616 0.5616
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0351 0.0903
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.029 0.0848
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0123 0.0123
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0695 0.0672
Loa Loa (eye worm) acetyltransferase 0.0158 0.1879 0.1982
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0123 0.0135
Loa Loa (eye worm) hypothetical protein 0.0111 0.125 0.1308
Brugia malayi metabotropic glutamate receptor type 2 0.0023 0.0086 0.0091
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0538 0.0515
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0341 0.9689
Schistosoma mansoni metabotropic glutamate receptor 0.0039 0.0302 0.0302
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.029 0.8079
Echinococcus granulosus histone acetyltransferase KAT2B 0.0152 0.1788 0.1768
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0123 0.0317
Echinococcus multilocularis dna polymerase eta 0.0043 0.0351 0.0327
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0125 0.01
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0636 0.0613
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0201 0.2443 0.2424
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.029 0.8079
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0636 0.0613
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0043 0.0038
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0636 0.0636
Schistosoma mansoni cpg binding protein 0.0031 0.0194 0.0194
Schistosoma mansoni twik family of potassium channels-related 0.0026 0.0136 0.0136
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0284 0.3535 0.3755
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0136 0.0349
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0027 0.0027
Echinococcus granulosus metabotropic glutamate receptor 5 0.0057 0.0545 0.0521
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0289 0.0265
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.013 0.0725
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0167 0.0143
Brugia malayi Bromodomain containing protein 0.0085 0.091 0.1056
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0026 0.0136 0.0111
Echinococcus granulosus geminin 0.0719 0.9289 0.9287
Schistosoma mansoni twik family of potassium channels-related 0.0026 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0043 0.0038
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0076 0.0195
Echinococcus granulosus potassium channel subfamily K 8 0.0026 0.0136 0.0111
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0026 0.0136 0.0111
Brugia malayi Pre-SET motif family protein 0.0032 0.0208 0.0234
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0351 0.1619
Loa Loa (eye worm) uncoordinated protein 58 0.0026 0.0136 0.0115
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0196 0.0503
Echinococcus multilocularis calcium activated potassium channel variant 0.0026 0.0136 0.0111
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0316 0.0292
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0447 0.0447
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0538 0.0538
Plasmodium vivax SET domain protein, putative 0.0032 0.0208 0.1371
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.0031 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0284 0.3535 0.3535
Trypanosoma cruzi ion transport protein, putative 0.0026 0.0136 0.0349
Echinococcus multilocularis tar DNA binding protein 0.0663 0.8541 0.8538
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0667 0.0667
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0043 0.0351 0.0346
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0026 0.0136 0.0149
Echinococcus granulosus dna polymerase eta 0.0043 0.0351 0.0327
Mycobacterium ulcerans hypothetical protein 0.0111 0.125 0.6338
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.0031 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Mycobacterium tuberculosis Conserved hypothetical protein 0.0043 0.0351 0.0339
Entamoeba histolytica hypothetical protein 0.0026 0.0123 0.287
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0176 0.0452
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0208 0.0208
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0538 0.0515
Loa Loa (eye worm) MBCTL1 0.0057 0.0538 0.0546
Brugia malayi hypothetical protein 0.0026 0.0136 0.0149
Schistosoma mansoni twik family of potassium channels-related 0.0026 0.0136 0.0136
Echinococcus granulosus snurportin 1 0.0331 0.4162 0.4147
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.0447 0.0424
Schistosoma mansoni hypothetical protein 0.0029 0.0167 0.0167
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0297 0.0297
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0026 0.0136 0.0115
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.125 0.1327
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0167 0.0167
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0425 0.3229
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0136 0.0342
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0167 0.0143
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0026 0.0136 0.0111
Brugia malayi hypothetical protein 0.0097 0.1064 0.1237
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0425 0.3229
Plasmodium vivax hypothetical protein, conserved 0.0111 0.125 1
Echinococcus granulosus dnaJ subfamily B 0.044 0.56 0.5589
Toxoplasma gondii hypothetical protein 0.005 0.0448 0.3415
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0043 0.0041
Brugia malayi Bromodomain containing protein 0.0035 0.025 0.0284
Schistosoma mansoni twik family of potassium channels-related 0.0026 0.0136 0.0136
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0538 0.0515
Trypanosoma cruzi ion transport protein, putative 0.0026 0.0136 0.0349
Echinococcus granulosus importin subunit beta 1 0.0031 0.0196 0.0172
Echinococcus multilocularis twik family of potassium channels 0.0026 0.0136 0.0111
Leishmania major potassium channel subunit-like protein 0.0026 0.0136 0.0349
Echinococcus multilocularis potassium channel subfamily K 0.0026 0.0136 0.0111
Onchocerca volvulus 0.0111 0.125 0.3787
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0136 0.0342
Schistosoma mansoni cpg binding protein 0.0035 0.0244 0.0244
Echinococcus multilocularis cpg binding protein 0.0035 0.0244 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Trichomonas vaginalis esterase, putative 0.0111 0.125 0.3999
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0208 0.0208
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0026 0.0136 0.0149
Leishmania major calcium/potassium channel (CAKC), putative 0.0026 0.0136 0.0349
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Brugia malayi Pre-SET motif family protein 0.0219 0.2679 0.313
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0196 0.0503
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0026 0.0136 0.0342
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0025 0.0025
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0351 0.0903
Onchocerca volvulus 0.0111 0.125 0.3787
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.013 0.0336
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0311 0.3888 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.2679 0.2838
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.029 0.0745
Loa Loa (eye worm) beta-lactamase 0.0111 0.125 0.1308
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0351 0.0903
Loa Loa (eye worm) hypothetical protein 0.0111 0.125 0.1308
Mycobacterium tuberculosis Conserved protein 0.0111 0.125 0.1327
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0311 0.3888 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.1064 0.1109
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0026 0.0136 0.0149
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0026 0.013 0.0109
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0026 0.0136 0.0149
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.013 0.2934
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0351 0.0402
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0026 0.0136 0.0111
Echinococcus multilocularis potassium channel subfamily K 8 0.0026 0.0136 0.0111
Schistosoma mansoni calcium-activated potassium channel 0.0026 0.0136 0.0136
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0431 0.0495
Giardia lamblia Hypothetical protein 0.0026 0.0136 0.3254
Trypanosoma brucei DNA polymerase eta, putative 0.0043 0.0351 0.0903
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0538 0.0621
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0184 0.016
Loa Loa (eye worm) glutamate receptor 0.0047 0.0402 0.04
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0088 0.0225
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0227 0.0256
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0026 0.0136 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Schistosoma mansoni alpha-glucosidase 0.0148 0.1741 0.1741
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0636 0.3114
Plasmodium vivax potassium channel, putative 0.0026 0.0136 0.0767
Loa Loa (eye worm) hypothetical protein 0.0049 0.0431 0.0431
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0447 0.0423
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Schistosoma mansoni tar DNA-binding protein 0.0663 0.8541 0.8541
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Brugia malayi beta-lactamase family protein 0.0111 0.125 0.1455
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Giardia lamblia DINP protein human, muc B family 0.0043 0.0351 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0167 0.111
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0447 0.0447
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0043 0.5
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.0031 0.0081
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Leishmania major importin beta-1 subunit, putative 0.0025 0.0118 0.0304
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Trypanosoma brucei unspecified product 0.003 0.0176 0.0452
Loa Loa (eye worm) hypothetical protein 0.0049 0.0439 0.044
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0447 0.1058
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0026 0.0136 0.0149
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0026 0.0136 0.0115
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Schistosoma mansoni tar DNA-binding protein 0.0663 0.8541 0.8541
Schistosoma mansoni ran 0.0023 0.0088 0.0088
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0043 0.0111
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.125 0.1455
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0447 0.0423
Loa Loa (eye worm) hypothetical protein 0.0047 0.0407 0.0405
Schistosoma mansoni zinc finger protein 0.0026 0.0134 0.0134
Schistosoma mansoni metabotropic glutamate receptor 0.0023 0.0086 0.0086
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.013 0.0336
Leishmania major hypothetical protein, conserved 0.0026 0.013 0.0336
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.1033 0.1011
Echinococcus granulosus metabotropic glutamate receptor 2 0.0039 0.0302 0.0278
Entamoeba histolytica Ran family GTPase 0.0023 0.0088 0.1752
Mycobacterium tuberculosis Conserved protein 0.0111 0.125 0.1327
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0363 0.0933
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0341 0.9689
Schistosoma mansoni bromodomain containing protein 0.0073 0.0745 0.0745
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0118 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Brugia malayi jmjC domain containing protein 0.0094 0.1033 0.1201
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.0031 0.0081
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0425 0.1292
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.013 0.0336
Loa Loa (eye worm) hypothetical protein 0.0111 0.125 0.1308
Loa Loa (eye worm) hypothetical protein 0.0057 0.0545 0.0553
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0043 0.0351 0.0327
Loa Loa (eye worm) hypothetical protein 0.0272 0.3382 0.3591
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.0031 0.0007
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0351 0.0327
Leishmania major hypothetical protein, conserved 0.0026 0.0136 0.0349
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.029 0.0848
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0123 0.0099
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0031 0.0027
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.125 0.3999
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0167 0.111
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0284 0.3535 0.3535
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0088 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0227 0.0213
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0777 0.0777
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0123 0.0317
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0026 0.0136 0.0149
Schistosoma mansoni hypothetical protein 0.0022 0.0075 0.0075
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.029 0.033
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.125 0.1327
Plasmodium vivax importin-beta 2, putative 0.0031 0.0196 0.1266
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0425 0.3165
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.029 0.0848
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0311 0.3888 1
Loa Loa (eye worm) hypothetical protein 0.0257 0.3187 0.3383
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.029 0.0266
Brugia malayi PHD-finger family protein 0.0032 0.0208 0.0234
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0351 0.0903
Schistosoma mansoni hypothetical protein 0.0725 0.9367 0.9367
Brugia malayi Bromodomain containing protein 0.0044 0.0372 0.0427
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0331 0.4162 0.4426
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.029 0.0745
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.2057 0.2037
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.0031 0.0081
Echinococcus granulosus potassium channel subfamily K 0.0026 0.0136 0.0111
Brugia malayi beta-lactamase 0.0111 0.125 0.1455
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0031 0.0027
Schistosoma mansoni twik family of potassium channels-related 0.0026 0.0136 0.0136
Schistosoma mansoni ran 0.0023 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.0031 0.0081
Plasmodium falciparum importin beta, putative 0.0031 0.0196 0.5121
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0351 0.105
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Mycobacterium leprae conserved hypothetical protein 0.0111 0.125 0.5
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0026 0.0136 0.0349
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Schistosoma mansoni calcium-activated potassium channel 0.0026 0.0136 0.0136
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.125 0.3999
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0363 0.0933
Brugia malayi hypothetical protein 0.0026 0.013 0.0143
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0136 0.0349
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0026 0.0136 0.0149
Plasmodium falciparum phd finger protein, putative 0.0029 0.0167 0.415
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0115
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0636 0.3114
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0088 0.0093
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0088 0.1752
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.1879 0.1879
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0026 0.0136 0.0149
Giardia lamblia PHD finger protein 15 0.0029 0.0167 0.4231
Echinococcus multilocularis geminin 0.0719 0.9289 0.9287
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0043 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0176 0.0452
Loa Loa (eye worm) hypothetical protein 0.0725 0.9367 1
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0026 0.0136 0.0102
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0026 0.0136 0.0149
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.0031 0.0007
Schistosoma mansoni terminal deoxycytidyl transferase 0.0043 0.0351 0.0351
Toxoplasma gondii ABC1 family protein 0.0111 0.125 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0043 0.0111
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.0031 0.0003
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0447 0.0423
Schistosoma mansoni alpha glucosidase 0.0038 0.029 0.029
Echinococcus multilocularis peregrin 0.0035 0.025 0.0226
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0088 0.0369
Schistosoma mansoni alpha-glucosidase 0.0148 0.1741 0.1741
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0431 0.0431
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0363 0.0933
Brugia malayi RNA, U transporter 1 0.0088 0.0951 0.1105
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0031 0.0031
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0026 0.0136 0.0149
Loa Loa (eye worm) hypothetical protein 0.0169 0.202 0.2133
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0053 0.0487 0.0487
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0088 0.0063
Mycobacterium ulcerans beta-lactamase 0.0111 0.125 0.6338
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.2057 0.2037
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0201 0.2443 0.2424
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0431 0.0495
Plasmodium falciparum potassium channel 0.0026 0.0136 0.3102
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0695 0.0672
Brugia malayi CXXC zinc finger family protein 0.0031 0.0194 0.0218
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0118 0.0285
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.125 0.3214

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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