Detailed information for compound 731202

Basic information

Technical information
  • TDR Targets ID: 731202
  • Name: methyl 4-chloro-3-[[2-[[4-(trifluoromethyl)-5 ,6,7,8-tetrahydroquinazolin-2-yl]sulfanyl]ace tyl]amino]benzoate
  • MW: 459.87 | Formula: C19H17ClF3N3O3S
  • H donors: 1 H acceptors: 4 LogP: 4.58 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(c(c1)NC(=O)CSc1nc2CCCCc2c(n1)C(F)(F)F)Cl
  • InChi: 1S/C19H17ClF3N3O3S/c1-29-17(28)10-6-7-12(20)14(8-10)24-15(27)9-30-18-25-13-5-3-2-4-11(13)16(26-18)19(21,22)23/h6-8H,2-5,9H2,1H3,(H,24,27)
  • InChiKey: BFGZJNJVTKOWCE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-chloro-3-[[1-oxo-2-[[4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl]thio]ethyl]amino]benzoic acid methyl ester
  • 4-chloro-3-[[2-[[4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl]thio]acetyl]amino]benzoic acid methyl ester
  • methyl 4-chloro-3-[2-[[4-(trifluoromethyl)-5,6,7,8-tetrahydroquinazolin-2-yl]sulfanyl]ethanoylamino]benzoate
  • CBKinase1_024779
  • CBKinase1_012379

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0238 0.0236
Toxoplasma gondii ran binding protein 0.0317 0.1482 0.3438
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0117 0.0503 0.1171
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0014 0.0009
Mycobacterium tuberculosis Probable reductase 0.0126 0.055 0.4769
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.012 0.0279
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Schistosoma mansoni microtubule-associated protein tau 0.1443 0.6997 1
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0011
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.012 0.0519 0.4497
Loa Loa (eye worm) hypothetical protein 0.008 0.0322 0.0749
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0016 0.001 0.0008
Giardia lamblia Kinase, NEK 0.0017 0.0014 0.0095
Schistosoma mansoni cpg binding protein 0.0064 0.0243 0.0345
Mycobacterium tuberculosis Probable dehydrogenase 0.0126 0.055 0.4769
Schistosoma mansoni peter pan-related 0.0016 0.001 0.0011
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.012 0.0519 0.0739
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0126 0.055 0.4769
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0021 0.0019
Brugia malayi hypothetical protein 0.0042 0.0137 0.032
Loa Loa (eye worm) hypothetical protein 0.0039 0.012 0.0277
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.012 0.0943
Trypanosoma brucei metacaspase 5, putative 0.0104 0.0439 0.2592
Echinococcus granulosus lysine specific demethylase 5A 0.0072 0.0285 0.0283
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0025 0.0053 0.092
Schistosoma mansoni lamin 0.0027 0.0061 0.0085
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0168 0.0751 0.4481
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0016 0.001 0.0018
Echinococcus multilocularis peptidase Clp (S14 family) 0.012 0.0519 0.0517
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0022 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Schistosoma mansoni hypothetical protein 0.0037 0.0112 0.0157
Schistosoma mansoni peter pan-related 0.0016 0.001 0.0011
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0317 0.1482 0.3454
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0021 0.0026
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Giardia lamblia Ser/Thr protein kinase 0.0016 0.001 0.00000027071
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0032 0.0075
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0021 0.0047
Brugia malayi jmjC domain containing protein 0.0069 0.0268 0.0626
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0141 0.0619 0.7044
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0025 0.0099
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.005 0.0175 0.0996
Brugia malayi RING zinc finger protein 0.0016 0.001 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0225 0.052
Echinococcus granulosus GPCR family 2 0.0037 0.0112 0.011
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0057 0.0284
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0016 0.001 0.0008
Brugia malayi YY1-associated factor 2 0.0317 0.1482 0.3454
Onchocerca volvulus Huntingtin homolog 0.0128 0.0559 0.1281
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.012 0.0943
Schistosoma mansoni hypothetical protein 0.089 0.4291 0.6132
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0025 0.0091
Loa Loa (eye worm) hypothetical protein 0.035 0.1646 0.3834
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.0569 0.081
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0025 0.0091
Brugia malayi Zinc finger protein 183 homolog 0.0016 0.0011 0.0025
Brugia malayi Latrophilin receptor protein 2 0.0037 0.0112 0.0261
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0134 0.0589 0.512
Treponema pallidum NADH oxidase 0.0019 0.0025 0.0038
Chlamydia trachomatis SWIB complex protein 0.089 0.4291 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0134 0.0589 0.6904
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Echinococcus multilocularis neuropeptide receptor A26 0.0488 0.2321 0.232
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0014 0.0024
Echinococcus granulosus Zinc finger RanBP2 type 0.0317 0.1482 0.148
Schistosoma mansoni Smad4 0.0025 0.0055 0.0075
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0053 0.0258
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.012 0.0168
Leishmania major hypothetical protein, conserved 0.0317 0.1482 0.8898
Brugia malayi isocitrate dehydrogenase 0.0017 0.0014 0.0032
Schistosoma mansoni rnf5 0.0016 0.001 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0476 0.1104
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0015 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Plasmodium falciparum metacaspase-like protein 0.0104 0.0439 0.1002
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.012 0.0665
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0183 0.0829 0.1884
Schistosoma mansoni smad 0.0025 0.0055 0.0075
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0073 0.0291 0.0289
Mycobacterium ulcerans hypothetical protein 0.0039 0.012 0.1191
Echinococcus granulosus snurportin 1 0.0361 0.1698 0.1696
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0025 0.0091
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0046
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0033 0.0031
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0055 0.0053
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0096 0.0523
Onchocerca volvulus 0.0317 0.1482 0.3438
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0028
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.0268 0.0266
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.012 0.0519 0.0739
Onchocerca volvulus 0.0489 0.2327 0.5411
Onchocerca volvulus 0.006 0.0227 0.0506
Onchocerca volvulus Huntingtin homolog 0.0128 0.0559 0.1281
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0111 0.0476 0.0474
Schistosoma mansoni ran 0.0025 0.0053 0.0072
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0055 0.0075
Loa Loa (eye worm) hypothetical protein 0.0039 0.012 0.0277
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0354 0.1664 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0134 0.0589 0.1374
Brugia malayi Pre-SET motif family protein 0.043 0.2037 0.4746
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.012 0.0943
Trypanosoma brucei hypothetical protein, conserved 0.0317 0.1482 0.8898
Echinococcus granulosus neuropeptide receptor A26 0.0488 0.2321 0.232
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0134 0.0589 0.084
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.012 0.0168
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0014 0.0009
Brugia malayi Zinc finger, C2H2 type family protein 0.0016 0.001 0.0023
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0104 0.0439 0.1022
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Trichomonas vaginalis ankyrin, putative 0.0016 0.001 0.0018
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0021 0.0027
Echinococcus granulosus caspase 2 0.02 0.0912 0.091
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0025 0.0053 0.01
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0012
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0021 0.0027
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0002 0.0005
Brugia malayi jmjC domain containing protein 0.0018 0.0021 0.0049
Brugia malayi brahma associated protein 60 kDa 0.089 0.4291 1
Brugia malayi hypothetical protein 0.0016 0.001 0.0023
Echinococcus granulosus phd:f box containing protein 0.0018 0.0021 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0117 0.0503 0.1171
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0245 0.0243
Brugia malayi intermediate filament protein 0.0027 0.0061 0.0143
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0057 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0439 0.1018
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.012 0.0943
Echinococcus granulosus zinc finger protein Ran binding 0.0317 0.1482 0.148
Brugia malayi MH2 domain containing protein 0.0025 0.0055 0.0128
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0014 0.0012
Plasmodium vivax hypothetical protein, conserved 0.089 0.4291 1
Schistosoma mansoni cpg binding protein 0.006 0.0227 0.0321
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0034 0.0096 0.0223
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0245 0.0243
Leishmania major importin beta-1 subunit, putative 0.0027 0.0065 0.0334
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.008 0.0323 0.0459
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0476 0.1104
Brugia malayi hypothetical protein 0.0016 0.001 0.0023
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0016 0.001 0.0018
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0104 0.0439 0.1002
Schistosoma mansoni survival motor neuron protein 0.0049 0.0169 0.0238
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.012 0.0665
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0245 0.0549
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0285 0.0663
Schistosoma mansoni intermediate filament proteins 0.0027 0.0061 0.0085
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.006 0.0225 0.0503
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0022 0.0259
Brugia malayi Melibiase family protein 0.008 0.0323 0.0753
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0141 0.0619 0.5384
Brugia malayi RNA, U transporter 1 0.0096 0.0402 0.0936
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0014 0.0009
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0021 0.0027
Leishmania major hypothetical protein, conserved 0.0026 0.0057 0.0284
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0016 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0128 0.0559 0.13
Brugia malayi CXXC zinc finger family protein 0.006 0.0227 0.0528
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0361 0.1698 0.3955
Leishmania major hypothetical protein, conserved 0.0317 0.1482 0.8898
Onchocerca volvulus 0.0097 0.0404 0.092
Loa Loa (eye worm) hypothetical protein 0.0317 0.1482 0.3452
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0001 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0073
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0104 0.0439 0.0624
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0183 0.0829 0.1912
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0183 0.0829 0.1912
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Trypanosoma cruzi metacaspase, putative 0.0104 0.0439 0.2592
Schistosoma mansoni hypothetical protein 0.0042 0.0137 0.0193
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0183 0.0829 0.9813
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0202 0.0466
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0014 0.0009
Mycobacterium tuberculosis Probable oxidoreductase 0.0141 0.0619 0.5384
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0055 0.0053
Schistosoma mansoni smad1 5 8 and 0.0025 0.0055 0.0075
Loa Loa (eye worm) hypothetical protein 0.0317 0.1482 0.3452
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.012 0.1191
Brugia malayi beta-lactamase 0.0039 0.012 0.0279
Trypanosoma cruzi polo-like protein kinase, putative 0.0111 0.0476 0.2816
Toxoplasma gondii exonuclease III APE 0.0019 0.0022 0.0028
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0061 0.0228 0.1318
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0238 0.0236
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.012 0.0943
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.012 0.0274
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0065 0.0147
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0025 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0035 0.0047
Brugia malayi latrophilin 2 splice variant baaae 0.008 0.0322 0.0751
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0183 0.0829 0.1912
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0317 0.1482 0.3438
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0016 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0053 0.0121
Echinococcus granulosus ring finger protein 170 0.0016 0.001 0.0008
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0019 0.0025 0.0037
Mycobacterium tuberculosis Conserved protein 0.0039 0.012 0.0943
Loa Loa (eye worm) MH2 domain-containing protein 0.0371 0.1749 0.4075
Trypanosoma cruzi polo-like protein kinase, putative 0.0111 0.0476 0.2816
Loa Loa (eye worm) hypothetical protein 0.0301 0.1405 0.3272
Entamoeba histolytica hypothetical protein 0.0042 0.0137 0.2738
Schistosoma mansoni hypothetical protein 0.008 0.0322 0.0457
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0317 0.1482 0.3454
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.008 0.0323 0.0748
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0012
Plasmodium vivax thioredoxin reductase, putative 0.0055 0.0202 0.045
Mycobacterium ulcerans lipase LipD 0.0039 0.012 0.1191
Leishmania major hypothetical protein, conserved 0.0317 0.1482 0.8898
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0021 0.0026
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0019 0.0025 0.0037
Giardia lamblia NADH oxidase lateral transfer candidate 0.0019 0.0025 0.0325
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0183 0.0829 1
Brugia malayi MH2 domain containing protein 0.0025 0.0055 0.0128
Schistosoma mansoni hypothetical protein 0.089 0.4291 0.6132
Brugia malayi B-box zinc finger family protein 0.0016 0.001 0.0023
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.001 0.0018
Trichomonas vaginalis esterase, putative 0.0039 0.012 0.0274
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0168 0.0751 0.4481
Chlamydia trachomatis DNA topoisomerase I 0.089 0.4291 1
Echinococcus multilocularis ring and YY1 binding protein 0.0317 0.1482 0.148
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0014 0.0024
Plasmodium falciparum metacaspase 1 0.0104 0.0439 0.1002
Echinococcus granulosus voltage gated potassium channel 0.0021 0.0035 0.0033
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0025 0.0035
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0238 0.0236
Schistosoma mansoni peptidase Clp (S14 family) 0.0183 0.0829 0.1181
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0025 0.0091
Trypanosoma cruzi metacaspase 5, putative 0.0104 0.0439 0.2592
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0016 0.001 0.0023
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0021 0.0019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0012
Schistosoma mansoni smad1 5 8 and 0.0025 0.0055 0.0075
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0057 0.011
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0055 0.0053
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Mycobacterium tuberculosis Conserved hypothetical protein 0.0186 0.0844 0.7384
Leishmania major trypanothione reductase 0.0055 0.0202 0.1163
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0439 0.1018
Echinococcus granulosus ring finger protein 113a 0.0016 0.0011 0.0009
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0168 0.0751 0.4481
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0245 0.142
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0225 0.052
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Mycobacterium tuberculosis Conserved protein 0.0039 0.012 0.0943
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0039
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.089 0.4291 1
Giardia lamblia Kinase, CMGC MAPK 0.006 0.0225 0.4621
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Trypanosoma cruzi metacaspase 5, putative 0.0104 0.0439 0.2592
Brugia malayi hypothetical protein 0.0016 0.001 0.0023
Brugia malayi brahma associated protein 60 kDa 0.089 0.4291 1
Trypanosoma brucei trypanothione reductase 0.0055 0.0202 0.1163
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0021 0.0067
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0021 0.0019
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0073 0.0291 0.0289
Echinococcus granulosus intermediate filament protein 0.0027 0.0061 0.0059
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.1096 0.1094
Echinococcus multilocularis geminin 0.0199 0.0903 0.0902
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0021 0.0027
Loa Loa (eye worm) RiNg Finger protein family member 0.0016 0.0011 0.0023
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0025 0.0053 0.0259
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0096 0.0094
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0025 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0476 0.1104
Echinococcus multilocularis snurportin 1 0.0361 0.1698 0.1696
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0245 0.0347
Loa Loa (eye worm) Smad1 0.0025 0.0055 0.0126
Leishmania major mitochondrial DNA polymerase beta 0.0354 0.1664 1
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0317 0.1482 0.8898
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0016 0.001 0.0008
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0317 0.1482 0.8898
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.012 0.0118
Echinococcus granulosus apoptotic protease activating factor 1 0.0097 0.0404 0.0402
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0015 0.0013
Mycobacterium ulcerans hypothetical protein 0.0186 0.0844 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0025 0.0035
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0025 0.0091
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0021 0.0019
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.012 0.0519 0.0739
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0014 0.0032
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0022 0.0073
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.006 0.0225 0.1301
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Trypanosoma cruzi WLM domain containing protein, putative 0.0317 0.1482 0.8898
Schistosoma mansoni zinc finger protein 0.0317 0.1482 0.2116
Echinococcus granulosus muscleblind protein 0.035 0.1646 0.1644
Brugia malayi jmjC domain containing protein 0.0072 0.0285 0.0665
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0057 0.0284
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0025 0.0091
Leishmania major hypothetical protein, conserved 0.0317 0.1482 0.8898
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.012 0.0943
Loa Loa (eye worm) hypothetical protein 0.0026 0.0057 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0439 0.1018
Loa Loa (eye worm) hypothetical protein 0.0128 0.0559 0.13
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0022 0.0049
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0354 0.1664 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0057 0.011
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0063 0.024 0.2706
Brugia malayi glutathione reductase 0.0055 0.0202 0.0471
Trichomonas vaginalis ion channel nompc, putative 0.0016 0.001 0.0018
Echinococcus granulosus caspase 8 0.0104 0.0439 0.0437
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0225 0.052
Echinococcus multilocularis Smad4 0.0025 0.0055 0.0053
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0024
Onchocerca volvulus 0.0039 0.012 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.008
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.012 0.0274
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0037 0.0112 0.011
Loa Loa (eye worm) RING finger protein 20 0.0016 0.001 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0025 0.0091
Plasmodium falciparum thioredoxin reductase 0.0055 0.0202 0.045
Brugia malayi jmjC domain containing protein 0.0018 0.0021 0.0049
Echinococcus multilocularis SWI:SNF matrix associated 0.089 0.4291 0.429
Plasmodium vivax JmjC domain containing protein 0.0018 0.0021 0.0026
Schistosoma mansoni hypothetical protein 0.0016 0.0011 0.0013
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Brugia malayi RING finger protein 20 0.0016 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0238 0.1096 0.2553
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0097 0.0404 0.0939
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0069 0.0267 0.0618
Plasmodium falciparum importin beta, putative 0.0034 0.0096 0.0202
Onchocerca volvulus 0.0312 0.1457 0.3379
Brugia malayi MH1 domain containing protein 0.0025 0.0055 0.0128
Schistosoma mansoni brg-1 associated factor 0.089 0.4291 0.6132
Plasmodium vivax importin-beta 2, putative 0.0034 0.0096 0.0202
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.012 0.0519 0.0739
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0033 0.0076
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0137 0.0135
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0317 0.1482 0.148
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0014 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.012 0.0274
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Brugia malayi Muscleblind-like protein 0.035 0.1646 0.3835
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0061 0.0141
Echinococcus granulosus Upstream activation factor subunit UAF30 0.089 0.4291 0.429
Echinococcus granulosus microtubule associated protein 2 0.1443 0.6997 0.6997
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0317 0.1482 0.8898
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Plasmodium falciparum glutathione reductase 0.0055 0.0202 0.045
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0183 0.0829 0.0827
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0021 0.0019
Trichomonas vaginalis ankyrin, putative 0.0016 0.001 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0476 0.0677
Echinococcus multilocularis musashi 0.0027 0.0061 0.0059
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0126 0.055 0.6069
Onchocerca volvulus 0.0317 0.1482 0.3438
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0111 0.0476 0.1107
Trypanosoma cruzi hypothetical protein, conserved 0.0317 0.1482 0.8898
Leishmania major metacaspase, putative 0.0104 0.0439 0.2592
Loa Loa (eye worm) glutathione reductase 0.0055 0.0202 0.047
Plasmodium vivax SET domain protein, putative 0.0063 0.0238 0.0534
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0028
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.095 0.4585 0.4584
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0117 0.0503 0.1172
Echinococcus multilocularis cpg binding protein 0.0064 0.0243 0.0241
Brugia malayi serine/threonine-protein kinase plk-2 0.0111 0.0476 0.1109
Echinococcus multilocularis dnaJ subfamily B 0.086 0.4141 0.4139
Echinococcus multilocularis apoptotic protease activating factor 1 0.0097 0.0404 0.0402
Echinococcus granulosus Smad4 0.0025 0.0055 0.0053
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0014 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Toxoplasma gondii thioredoxin reductase 0.0055 0.0202 0.045
Loa Loa (eye worm) hypothetical protein 0.02 0.0912 0.2123
Brugia malayi Cytochrome P450 family protein 0.0025 0.0053 0.0122
Brugia malayi hypothetical protein 0.0026 0.0057 0.0132
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0125 0.0545 0.1269
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Toxoplasma gondii Alpha-galactosidase 0.0017 0.0014 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0025 0.0091
Onchocerca volvulus Serine\/threonine kinase homolog 0.0111 0.0476 0.1088
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0175 0.0996
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0439 0.1018
Echinococcus multilocularis GPCR, family 2 0.0037 0.0112 0.011
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0021 0.0067
Loa Loa (eye worm) latrophilin receptor protein 2 0.0037 0.0112 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Leishmania major hypothetical protein, conserved 0.0317 0.1482 0.8898
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.001 0.0018
Loa Loa (eye worm) thioredoxin reductase 0.0055 0.0202 0.047
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0016 0.001 0.0008
Brugia malayi hypothetical protein 0.0016 0.001 0.0023
Schistosoma mansoni hypothetical protein 0.0037 0.0112 0.0157
Schistosoma mansoni zinc finger protein 0.0016 0.001 0.0011
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0053 0.0121
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0245 0.2711
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.012 0.0274
Entamoeba histolytica hypothetical protein 0.0027 0.0065 0.1186
Schistosoma mansoni ran 0.0025 0.0053 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.089 0.4291 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0055 0.0126
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0047
Echinococcus multilocularis ring finger protein 113a 0.0016 0.0011 0.0009
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0028
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0141 0.0619 0.5384
Entamoeba histolytica serine/threonine protein kinase, putative 0.0111 0.0476 1
Loa Loa (eye worm) hypothetical protein 0.035 0.1646 0.3834
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0317 0.1482 0.148
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.089 0.4291 1
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Echinococcus granulosus SWI:SNF matrix associated 0.089 0.4291 0.429
Entamoeba histolytica hypothetical protein 0.0042 0.0137 0.2738
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0002 0.0003
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0137 0.0193
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0053 0.0258
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0134 0.0589 0.3503
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0183 0.0829 0.9813
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0285 0.0405
Echinococcus granulosus geminin 0.0199 0.0903 0.0902
Trypanosoma cruzi metacaspase, putative 0.0104 0.0439 0.2592
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0202 0.0466
Echinococcus multilocularis caspase 3 0.017 0.0766 0.0764
Onchocerca volvulus 0.0027 0.0061 0.012
Loa Loa (eye worm) transcription factor SMAD2 0.0371 0.1749 0.4075
Onchocerca volvulus 0.0301 0.1405 0.3258
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0169 0.0393
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0025 0.0091
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.089 0.4291 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0238 0.0338
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0053 0.0123
Onchocerca volvulus 0.089 0.4291 1
Echinococcus multilocularis Glycoside hydrolase, family 27 0.012 0.0519 0.0517
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0025 0.0091
Brugia malayi Thioredoxin reductase 0.0055 0.0202 0.0471
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0011
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.012 0.0519 0.0517
Echinococcus granulosus cpg binding protein 0.0064 0.0243 0.0241
Mycobacterium tuberculosis Conserved protein 0.0039 0.012 0.0943
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0183 0.0829 1
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0024
Schistosoma mansoni lamin 0.0027 0.0061 0.0085
Brugia malayi MAP kinase sur-1 0.006 0.0225 0.0525
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0019 0.0025 0.0037
Leishmania major hypothetical protein, conserved 0.0039 0.012 0.0665
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.043 0.2037 0.4745
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Trichomonas vaginalis hypothetical protein 0.0016 0.001 0.0018
Brugia malayi Neuralized family protein 0.0016 0.001 0.0023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0073
Trypanosoma cruzi metacaspase, putative 0.0104 0.0439 0.2592
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0134 0.0589 0.0587
Toxoplasma gondii hypothetical protein 0.0057 0.021 0.0469
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0183 0.0829 1
Onchocerca volvulus 0.0049 0.0169 0.0371
Trypanosoma brucei metacaspase MCA2 0.0104 0.0439 0.2592
Trypanosoma brucei DNA polymerase beta thumb, putative 0.005 0.0175 0.0996
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Brugia malayi hypothetical protein 0.0312 0.1457 0.3395
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0025 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0317 0.1482 0.8898
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0065 0.0334
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0015 0.0013
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0022 0.0259
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0126 0.055 0.4769
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.005 0.0175 0.0996
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0061 0.0143
Loa Loa (eye worm) hypothetical protein 0.0039 0.012 0.0277
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0245 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0476 0.1104
Trypanosoma brucei metacaspase 0.0104 0.0439 0.2592
Trypanosoma brucei polo-like protein kinase 0.0111 0.0476 0.2816
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0025 0.0091
Onchocerca volvulus 0.0317 0.1482 0.3438
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.012 0.0519 0.4497
Mycobacterium ulcerans beta-lactamase 0.0039 0.012 0.1191
Echinococcus granulosus mitogen activated protein kinase 3 0.006 0.0225 0.0223
Echinococcus granulosus importin subunit beta 1 0.0034 0.0096 0.0094
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0016 0.001 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0476 0.1104
Brugia malayi Cell death protein 3 precursor 0.02 0.0912 0.2124
Brugia malayi hypothetical protein 0.0128 0.0559 0.1301
Echinococcus granulosus dnaJ subfamily B 0.086 0.4141 0.4139
Toxoplasma gondii hypothetical protein 0.0063 0.024 0.0538
Giardia lamblia Kinase, PLK 0.0111 0.0476 1
Echinococcus multilocularis mitogen activated protein kinase 0.006 0.0225 0.0223
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0015 0.0013
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0025 0.0053 0.01
Leishmania major cytochrome p450-like protein 0.0025 0.0053 0.0258
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0126 0.055 0.4769
Brugia malayi SWIB/MDM2 domain containing protein 0.089 0.4291 1
Echinococcus granulosus lamin 0.0027 0.0061 0.0059
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0053 0.0051
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.1138 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0037 0.0112 0.011
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0021 0.0035 0.0033
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0317 0.1482 0.8898
Echinococcus multilocularis microtubule associated protein 2 0.1443 0.6997 0.6997
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0069 0.0267 0.0618
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.0268 0.0266
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0002 0.0003
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.012 0.0519 0.0517
Loa Loa (eye worm) hypothetical protein 0.0063 0.0238 0.0554
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0354 0.1664 1
Echinococcus granulosus caspase 0.0274 0.1274 0.1272
Leishmania major hypothetical protein, conserved 0.0018 0.0021 0.0067
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0016 0.001 0.0008
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0016 0.001 0.0018
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0073 0.0291 0.0676
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0096 0.0523
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0037 0.0112 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0055 0.0053
Schistosoma mansoni RNA binding protein 0.0317 0.1482 0.2116
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0061 0.0141
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.012 0.1191
Brugia malayi Smad1 0.0025 0.0055 0.0128
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0137 0.0135
Onchocerca volvulus 0.0063 0.0238 0.0534
Onchocerca volvulus 0.0317 0.1482 0.3438
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0016 0.001 0.0018
Onchocerca volvulus Cell death protein 3 homolog 0.02 0.0912 0.2106
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0238 0.0338
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.089 0.4291 1
Giardia lamblia Kinase 0.0017 0.0014 0.0095
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.006 0.0225 0.1301
Giardia lamblia Kinase, NEK 0.0017 0.0014 0.0095
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0033 0.0031
Brugia malayi Cytochrome P450 family protein 0.0025 0.0053 0.0122
Echinococcus granulosus peptidase Clp S14 family 0.012 0.0519 0.0517
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0025 0.0091
Schistosoma mansoni jumonji domain containing protein 0.0069 0.0268 0.0381
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0021 0.0035 0.0033
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.006 0.0225 0.0523
Schistosoma mansoni caspase-7 (C14 family) 0.0274 0.1274 0.1817
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.012 0.0943
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.1096 0.1094
Brugia malayi hypothetical protein 0.0238 0.1096 0.2555
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Echinococcus multilocularis tumor protein p63 0.2056 1 1
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0274 0.1274 0.1272
Brugia malayi Calcitonin receptor-like protein seb-1 0.0117 0.0503 0.1172
Echinococcus granulosus ring and YY1 binding protein 0.0317 0.1482 0.148
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0317 0.1482 0.3454
Schistosoma mansoni ring finger protein 151 0.0016 0.001 0.0011
Brugia malayi MH1 domain containing protein 0.0025 0.0055 0.0128
Trypanosoma brucei metacaspase MCA3 0.0104 0.0439 0.2592
Echinococcus multilocularis neuropeptide s receptor 0.0488 0.2321 0.232
Loa Loa (eye worm) hypothetical protein 0.0312 0.1457 0.3393
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0053 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0022 0.0051
Trichomonas vaginalis ran, putative 0.0025 0.0053 0.0118
Schistosoma mansoni hypothetical protein 0.0049 0.0169 0.0238
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Loa Loa (eye worm) hypothetical protein 0.0037 0.0112 0.0259
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0038 0.0036
Brugia malayi hypothetical protein 0.0016 0.001 0.0023
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0017 0.0014 0.0017
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0016 0.001 0.0018
Echinococcus granulosus thioredoxin glutathione reductase 0.0055 0.0202 0.02
Schistosoma mansoni hypothetical protein 0.089 0.4291 0.6132
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0037 0.0112 0.011
Trichomonas vaginalis ankyrin, putative 0.0016 0.001 0.0018
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0065 0.0147
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0025 0.0058
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Brugia malayi MH2 domain containing protein 0.0371 0.1749 0.4077
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0025 0.0035
Trichomonas vaginalis set domain proteins, putative 0.0489 0.2327 0.5419
Schistosoma mansoni TRABID protein (C64 family) 0.0317 0.1482 0.2116
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0025 0.0033
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0134 0.0589 0.0587
Echinococcus granulosus smad 0.0025 0.0055 0.0053
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0025 0.0053
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0053 0.0259
Toxoplasma gondii melibiase subfamily protein 0.012 0.0519 0.1189
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.006 0.0225 0.1301
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0274 0.1274 0.1272
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.089 0.4291 1
Echinococcus granulosus cell growth regulator with ring finger domain 0.0016 0.001 0.0008
Trypanosoma cruzi WLM domain containing protein, putative 0.0317 0.1482 0.8898
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0126 0.055 0.4769
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Echinococcus granulosus mitogen activated protein kinase 0.006 0.0225 0.0223
Schistosoma mansoni cellular tumor antigen P53 0.0301 0.1405 0.2005
Trypanosoma cruzi hypothetical protein, conserved 0.0317 0.1482 0.8898
Schistosoma mansoni fusion 0.0317 0.1482 0.2116
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0111 0.0476 0.0474
Echinococcus multilocularis 0.0016 0.001 0.0008
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0317 0.1482 0.3438
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0003
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0016 0.001 0.0011
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0028
Echinococcus multilocularis thioredoxin glutathione reductase 0.0055 0.0202 0.02
Loa Loa (eye worm) hypothetical protein 0.0026 0.0059 0.0136
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0053 0.0051
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0227 0.0526
Schistosoma mansoni hypothetical protein 0.0199 0.0903 0.1289
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0225 0.1301
Echinococcus multilocularis RING finger protein 185 0.0016 0.001 0.0008
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.012 0.0665
Echinococcus multilocularis muscleblind protein 1 0.035 0.1646 0.1644
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0025 0.0091
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0317 0.1482 0.148
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Brugia malayi Importin beta-1 subunit 0.0034 0.0096 0.0225
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0057 0.0284
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0221 0.0219
Loa Loa (eye worm) hypothetical protein 0.008 0.0323 0.0751
Toxoplasma gondii ABC1 family protein 0.0039 0.012 0.0257
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.0268 0.0266
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0245 0.2711
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Plasmodium vivax metacaspase 1, putative 0.0104 0.0439 0.1002
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.012 0.0274
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0014 0.0017
Brugia malayi jmjC domain containing protein 0.0018 0.0021 0.0049
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0073 0.0291 0.0678
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0035 0.0047
Schistosoma mansoni jumonji/arid domain-containing protein 0.0072 0.0285 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Echinococcus granulosus lamin dm0 0.0027 0.0061 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0476 0.1104
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0016 0.001 0.0018
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0225 0.1301
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.0096 0.0202
Entamoeba histolytica hypothetical protein 0.0042 0.0137 0.2738
Schistosoma mansoni importin beta-1 0.0034 0.0096 0.0135
Schistosoma mansoni caspase-7 (C14 family) 0.02 0.0912 0.13
Loa Loa (eye worm) hypothetical protein 0.0039 0.012 0.0277
Echinococcus granulosus caspase 3 0.017 0.0766 0.0764
Brugia malayi hypothetical protein 0.0017 0.0012 0.0028
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0317 0.1482 0.8898
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0022 0.0072
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0055 0.0202 0.1677
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0021 0.0027
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0025 0.0053 0.01
Loa Loa (eye worm) hypothetical protein 0.0317 0.1482 0.3452
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0225 0.0319
Brugia malayi jmjC domain containing protein 0.0018 0.0021 0.0049
Trypanosoma brucei Metacaspase-4 0.0104 0.0439 0.2592
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0021 0.0047
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0104 0.0439 0.1018
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.0202 0.1163
Echinococcus multilocularis SWI:SNF matrix associated 0.089 0.4291 0.429
Brugia malayi Pre-SET motif family protein 0.0063 0.0238 0.0556
Trypanosoma brucei protein kinase, putative 0.006 0.0225 0.1301
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0025 0.0035
Schistosoma mansoni cpg binding protein 0.0064 0.0243 0.0345
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0238 0.0338
Onchocerca volvulus 0.0039 0.012 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0238 0.0338
Echinococcus multilocularis caspase 0.0274 0.1274 0.1272
Schistosoma mansoni hypothetical protein 0.086 0.4141 0.5916
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0183 0.0829 0.1884
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0025 0.0091
Loa Loa (eye worm) hypothetical protein 0.0064 0.0243 0.0565
Echinococcus multilocularis caspase 2 0.02 0.0912 0.091
Loa Loa (eye worm) hypothetical protein 0.0027 0.0061 0.0141
Plasmodium vivax hypothetical protein, conserved 0.0104 0.0439 0.1002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0014 0.003
Brugia malayi beta-lactamase family protein 0.0039 0.012 0.0279
Trypanosoma brucei hypothetical protein, conserved 0.0317 0.1482 0.8898
Echinococcus multilocularis mitogen activated protein kinase 3 0.006 0.0225 0.0223
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0021 0.0067
Echinococcus multilocularis lamin dm0 0.0027 0.0061 0.0059
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.006 0.0225 0.1301
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0025 0.0035
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0317 0.1482 0.3454
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0063 0.024 0.0538
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0047
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0016 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0097 0.0404 0.0574
Schistosoma mansoni hypothetical protein 0.0037 0.0112 0.0157
Schistosoma mansoni kinase 0.0057 0.0209 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0021 0.0047
Brugia malayi beta-lactamase family protein 0.0039 0.012 0.0279
Echinococcus multilocularis zinc finger protein Ran binding 0.0317 0.1482 0.148
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0025 0.0035
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0021 0.0026
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.006 0.0225 0.1301
Trypanosoma cruzi metacaspase, putative 0.0104 0.0439 0.2592
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.089 0.4291 0.429
Entamoeba histolytica hypothetical protein 0.0042 0.0137 0.2738
Plasmodium falciparum glutathione reductase 0.0019 0.0025 0.0035
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0021 0.0019
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0104 0.0439 0.1002
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0057 0.011
Echinococcus multilocularis muscleblind protein 0.035 0.1646 0.1644
Plasmodium vivax hypothetical protein, conserved 0.0039 0.012 0.0257
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0025 0.0091
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0324 0.046
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0063 0.024 0.0538
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0022 0.0073
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0016 0.001 0.0008
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0014 0.0024
Plasmodium vivax glutathione reductase, putative 0.0055 0.0202 0.045
Schistosoma mansoni hypothetical protein 0.0037 0.0112 0.0157
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0025 0.0091
Echinococcus multilocularis SWI:SNF matrix associated 0.089 0.4291 0.429
Schistosoma mansoni smad1 5 8 and 0.0025 0.0055 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0055 0.0126
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.012 0.0277
Onchocerca volvulus 0.0039 0.012 0.0257
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0053 0.0259
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0016 0.001 0.0008
Echinococcus multilocularis caspase 8 0.0104 0.0439 0.0437
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0104 0.0439 0.1002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0238 0.0534
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0021
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0021 0.0035 0.0082
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0317 0.1482 0.8898
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0104 0.0439 0.1021
Schistosoma mansoni hypothetical protein 0.0361 0.1698 0.2424
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0053 0.0121
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0063 0.024 0.1698
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0022 0.002
Echinococcus multilocularis lamin 0.0027 0.0061 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0439 0.1018
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0025 0.0091
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0037 0.0112 0.011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0502 0.1149
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0053 0.0372
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0476 0.1104
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0021 0.0019
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0065 0.0147
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.012 0.0118
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0225 0.052
Onchocerca volvulus 0.0027 0.0061 0.012
Loa Loa (eye worm) beta-lactamase 0.0039 0.012 0.0277
Brugia malayi hypothetical protein 0.0097 0.0404 0.0941
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.008 0.0323 0.0459
Plasmodium falciparum thioredoxin reductase 0.0019 0.0025 0.0035
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0183 0.0829 0.1912
Echinococcus granulosus RING finger protein 185 0.0016 0.001 0.0008
Schistosoma mansoni caspase-3 (C14 family) 0.0274 0.1274 0.1817
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.012 0.0519 0.5636
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0245 0.2711
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0053 0.0121
Schistosoma mansoni mind bomb 0.0016 0.001 0.0011
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0025 0.0038
Brugia malayi Probable ClpP-like protease 0.0183 0.0829 0.1931
Loa Loa (eye worm) brahma associated protein 0.089 0.4291 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0245 0.2055
Entamoeba histolytica Ran family GTPase 0.0025 0.0053 0.092
Loa Loa (eye worm) hypothetical protein 0.0317 0.1482 0.3452
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0317 0.1482 0.8898
Schistosoma mansoni voltage-gated potassium channel 0.008 0.0324 0.046
Giardia lamblia Protein 21.1 0.0016 0.001 0.00000027071
Loa Loa (eye worm) hypothetical protein 0.0039 0.012 0.0277
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0317 0.1482 0.3438
Schistosoma mansoni hypothetical protein 0.0317 0.1482 0.2116
Schistosoma mansoni hypothetical protein 0.0199 0.0903 0.1289
Loa Loa (eye worm) hypothetical protein 0.0183 0.0829 0.1929
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0038 0.0036
Echinococcus multilocularis ring finger protein 170 0.0016 0.001 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0134 0.0589 0.6904
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0183 0.0829 0.0827
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0016 0.001 0.0008
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.089 0.4291 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0025 0.0023
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0111 0.0476 0.2816
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0439 0.1018
Loa Loa (eye worm) hypothetical protein 0.0317 0.1482 0.3452
Echinococcus multilocularis voltage gated potassium channel 0.0021 0.0035 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0039 0.012 0.0277
Brugia malayi hypothetical protein 0.0016 0.001 0.0023
Leishmania major GTP-binding protein, putative 0.0025 0.0053 0.0259
Echinococcus multilocularis smad 0.0025 0.0055 0.0053
Leishmania major hypothetical protein, conserved 0.0016 0.001 0.000000076226
Echinococcus granulosus neuropeptide s receptor 0.0488 0.2321 0.232

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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