Detailed information for compound 787408

Basic information

Technical information
  • TDR Targets ID: 787408
  • Name: 3-[(1-acetyl-2-methyl-2,3-dihydroindol-5-yl)s ulfonyl]-N-(2,5-dimethoxyphenyl)propanamide
  • MW: 446.517 | Formula: C22H26N2O6S
  • H donors: 1 H acceptors: 4 LogP: 1.73 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1NC(=O)CCS(=O)(=O)c1ccc2c(c1)CC(N2C(=O)C)C)OC
  • InChi: 1S/C22H26N2O6S/c1-14-11-16-12-18(6-7-20(16)24(14)15(2)25)31(27,28)10-9-22(26)23-19-13-17(29-3)5-8-21(19)30-4/h5-8,12-14H,9-11H2,1-4H3,(H,23,26)
  • InChiKey: IHUXNDZJIVGQGJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(1-acetyl-2-methyl-indolin-5-yl)sulfonyl-N-(2,5-dimethoxyphenyl)propanamide
  • 3-[(1-acetyl-2-methyl-5-indolinyl)sulfonyl]-N-(2,5-dimethoxyphenyl)propanamide
  • 3-(1-acetyl-2-methyl-indolin-5-yl)sulfonyl-N-(2,5-dimethoxyphenyl)propionamide
  • N-(2,5-dimethoxyphenyl)-3-[(1-ethanoyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl]propanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0074 0.0579 0.067
Mycobacterium tuberculosis Conserved hypothetical protein 0.0161 0.1461 1
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Brugia malayi hypothetical protein 0.0027 0.0106 0.0219
Loa Loa (eye worm) hypothetical protein 0.0074 0.0579 0.1298
Plasmodium vivax proline--tRNA ligase, putative 0.0083 0.0674 0.0663
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.0337 0.0384
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Schistosoma mansoni lozenge 0.0056 0.0404 0.0562
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0053 0.0371 0.2465
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0109 0.0395
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0019 0.001
Onchocerca volvulus 0.0125 0.1102 0.25
Schistosoma mansoni caspase-7 (C14 family) 0.0154 0.1394 0.1937
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Echinococcus multilocularis lysosomal alpha glucosidase 0.0326 0.3129 0.368
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0074 0.0579 0.0861
Echinococcus granulosus lysosomal alpha glucosidase 0.0326 0.3129 0.434
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.003 0.0025
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0341 0.033
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0162 0.1469 0.221
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0053 0.0371 0.1459
Mycobacterium ulcerans integral membrane transport protein 0.0033 0.0173 0.1109
Leishmania major trypanothione reductase 0.005 0.0341 0.1168
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0106 0.0094
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0423 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0651 0.2597
Trypanosoma brucei sugar transporter, putative 0.0033 0.0173 0.0593
Trypanosoma cruzi metacaspase, putative 0.0081 0.0651 0.2229
Schistosoma mansoni bromodomain containing protein 0.0067 0.0512 0.0711
Schistosoma mansoni alpha glucosidase 0.0072 0.0567 0.0789
Plasmodium vivax vivapain-2 0.0018 0.0015 0.0004
Loa Loa (eye worm) sugar transporter 0.0033 0.0173 0.0363
Mycobacterium ulcerans hypothetical protein 0.0161 0.1461 0.9946
Schistosoma mansoni hypothetical protein 0.0171 0.1567 0.2178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0109 0.0227
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0033 0.0173 0.0191
Echinococcus multilocularis muscleblind protein 1 0.0155 0.1404 0.1644
Leishmania major cathepsin L-like protease 0.0067 0.0517 0.177
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0317 0.0425
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Trypanosoma brucei metacaspase MCA2 0.0081 0.0651 0.2229
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Giardia lamblia Prolyl-tRNA synthetase 0.0071 0.0555 0.5811
Echinococcus multilocularis neuropeptide receptor A26 0.049 0.4783 0.5633
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0326 0.3129 0.7167
Plasmodium vivax hexose transporter 0.0237 0.2229 0.222
Schistosoma mansoni caspase-7 (C14 family) 0.0206 0.1916 0.2663
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0071 0.0555 0.2242
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0517 0.177
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0579 0.2304
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0579 0.2304
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.003 0.0102
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2474 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0423 0.282
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0271 0.0926
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0651 0.2597
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0074 0.0579 0.079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0102 0.0366
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0033 0.0173 0.0162
Loa Loa (eye worm) hypothetical protein 0.0448 0.4359 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Toxoplasma gondii sugar transporter ST1 0.0033 0.0173 0.0245
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.0517 0.177
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0074 0.0579 0.079
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0053 0.0371 0.127
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0365 0.1251
Plasmodium falciparum calcium-dependent protein kinase 1 0.0074 0.0579 0.0569
Echinococcus granulosus lysyl tRNA synthetase 0.0053 0.0371 0.05
Trypanosoma cruzi sugar transporter, putative 0.0033 0.0173 0.0593
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0162 0.1469 1
Echinococcus multilocularis caspase 2 0.0206 0.1916 0.2248
Giardia lamblia Lysyl-tRNA synthetase 0.0053 0.0371 0.3845
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0053 0.0371 0.127
Trypanosoma brucei protein kinase, putative 0.011 0.0946 0.3239
Onchocerca volvulus 0.0448 0.4359 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.1115 0.7613
Leishmania major glucose transporter, lmgt1 0.0074 0.0579 0.1982
Plasmodium vivax SET domain protein, putative 0.0032 0.0155 0.0144
Loa Loa (eye worm) glutathione reductase 0.005 0.0341 0.075
Schistosoma mansoni sugar transporter 0.0033 0.0173 0.0241
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0946 0.3796
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.003 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0567 0.2257
Loa Loa (eye worm) hypothetical protein 0.0069 0.0534 0.1195
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.003 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Loa Loa (eye worm) hypothetical protein 0.0448 0.4359 1
Loa Loa (eye worm) hypothetical protein 0.0206 0.1916 0.4375
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0012
Echinococcus multilocularis muscleblind protein 0.0155 0.1404 0.1644
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0012 0.0003
Echinococcus multilocularis mitogen activated protein kinase 0.011 0.0946 0.1103
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0317 0.0425
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0987 0.6727
Schistosoma mansoni hypothetical protein 0.0125 0.1102 0.1531
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0317 0.0694
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0534 0.0743
Echinococcus granulosus Sugar transporter ERD6 protein 0.0033 0.0173 0.0225
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0053 0.0371 0.0683
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0033 0.0173 0.0241
Entamoeba histolytica hypothetical protein 0.0053 0.0371 0.6307
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0341 0.2272
Loa Loa (eye worm) hypothetical protein 0.0027 0.0106 0.0208
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0162 0.1469 1
Onchocerca volvulus 0.0033 0.0173 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0946 0.3796
Echinococcus granulosus caspase 0.0154 0.1394 0.1924
Schistosoma mansoni glucose transporter 0.0033 0.0173 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Plasmodium vivax sugar transporter, putative 0.0033 0.0173 0.0162
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0015 0.0005
Schistosoma mansoni peptidase Clp (S14 family) 0.0162 0.1469 0.2042
Leishmania major myo-inositol/proton symporter (MIT) 0.0033 0.0173 0.0593
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0019 0.003 0.0102
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0074 0.0579 0.0569
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0946 0.1315
Trypanosoma brucei THT1 - hexose transporter, putative 0.0074 0.0579 0.1982
Echinococcus multilocularis mitogen activated protein kinase 3 0.011 0.0946 0.1103
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.0337 0.0453
Echinococcus granulosus caspase 8 0.0081 0.0651 0.089
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Echinococcus granulosus muscleblind protein 0.0155 0.1404 0.1939
Trichomonas vaginalis sucrase-isomaltase, putative 0.0072 0.0567 0.2257
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.003 0.0102
Leishmania major hypothetical protein, conserved 0.0033 0.0173 0.0593
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0305 0.1192
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0033 0.0173 0.1115
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0341 0.075
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0163 0.0341
Onchocerca volvulus 0.0033 0.0173 0.0363
Echinococcus multilocularis lysyl tRNA synthetase 0.0053 0.0371 0.0424
Loa Loa (eye worm) hypothetical protein 0.0032 0.0163 0.0341
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0237 0.2229 0.2618
Echinococcus multilocularis calcium dependent protein kinase 0.0068 0.0524 0.0605
Loa Loa (eye worm) hypothetical protein 0.005 0.0337 0.074
Plasmodium falciparum calcium-dependent protein kinase 2 0.0074 0.0579 0.0569
Trypanosoma brucei THT1 - hexose transporter, putative 0.0074 0.0579 0.1982
Toxoplasma gondii sugar transporter ST2 0.0033 0.0173 0.0245
Onchocerca volvulus 0.0033 0.0173 0.0363
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0567 0.9792
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0102 0.0137
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0579 0.2304
Echinococcus multilocularis Protein lozenge 0.0056 0.0404 0.0464
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.022 0.2056 0.4697
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0015 0.0053
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0271 0.0926
Plasmodium falciparum lysine--tRNA ligase 0.0053 0.0371 0.036
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0163 0.0352
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0074 0.0579 0.1298
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0173 0.0657
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.003 0.0033
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.1115 0.7613
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0237 0.2229 0.3088
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0567 0.2257
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0154 0.1394 0.1924
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0651 0.2597
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Schistosoma mansoni glucose transport protein 0.0237 0.2229 0.3099
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0946 0.3239
Echinococcus granulosus mitogen activated protein kinase 3 0.011 0.0946 0.1301
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.0173 0.0375
Trypanosoma cruzi metacaspase, putative 0.0081 0.0651 0.2229
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0074 0.0579 0.0569
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0987 0.6727
Plasmodium falciparum calcium-dependent protein kinase 3 0.0074 0.0579 0.0569
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0567 0.1943
Leishmania major metacaspase, putative 0.0081 0.0651 0.2229
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0567 0.2257
Brugia malayi glutathione reductase 0.005 0.0341 0.076
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0057 0.0095
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0155 0.0169
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0029 0.0132 0.0267
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Trypanosoma cruzi target of rapamycin kinase 3 0.0019 0.003 0.0102
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0109 0.0373
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0102 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0473 0.0643
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1567 0.6317
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0015 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0271 0.0926
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0074 0.0579 0.1308
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0074 0.0579 0.0861
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.0173 0.0375
Onchocerca volvulus 0.0033 0.0173 0.0363
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0869 0.1974
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0053 0.0371 0.2465
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1567 0.6317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Trypanosoma brucei glucose transporter, putative 0.0074 0.0579 0.1982
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0173 0.0657
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.011 0.0946 0.2143
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0109 0.166
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trypanosoma brucei Metacaspase-4 0.0081 0.0651 0.2229
Schistosoma mansoni glucose transport protein 0.0237 0.2229 0.3099
Schistosoma mansoni microtubule-associated protein tau 0.0729 0.7194 1
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0104 0.0883 0.1028
Echinococcus granulosus cathepsin l1 0.0018 0.0015 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0317 0.044
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0883 0.1227
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0056 0.0399 0.0388
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2474 1
Trypanosoma brucei glucose transporter, putative 0.0074 0.0579 0.1982
Toxoplasma gondii transporter, major facilitator family protein 0.0033 0.0173 0.0245
Leishmania major cathepsin L-like protease 0.0067 0.0517 0.177
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0109 0.0395
Onchocerca volvulus 0.0033 0.0173 0.0363
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.1115 0.6997
Plasmodium vivax glutathione reductase, putative 0.005 0.0341 0.033
Onchocerca volvulus 0.025 0.2362 0.5402
Echinococcus granulosus solute carrier family 22 0.0033 0.0173 0.0225
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.003 0.0102
Brugia malayi Pre-SET motif family protein 0.022 0.2056 0.4703
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0012
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0081 0.0651 0.097
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0162 0.1469 0.221
Echinococcus granulosus microtubule associated protein 2 0.0729 0.7194 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0072 0.0567 0.2257
Echinococcus granulosus neuropeptide s receptor 0.049 0.4783 0.6643
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0883 0.1227
Echinococcus granulosus GPCR family 2 0.0032 0.0163 0.0211
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0015 0.0053
Schistosoma mansoni lysyl-tRNA synthetase 0.0053 0.0371 0.0516
Trypanosoma cruzi metacaspase 5, putative 0.0081 0.0651 0.2229
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0072 0.0567 0.0843
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0987 0.6727
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0337 0.0468
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Leishmania major alpha glucosidase II subunit, putative 0.0072 0.0567 0.1943
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0423 0.0588
Loa Loa (eye worm) hypothetical protein 0.0081 0.0651 0.1463
Giardia lamblia Hexose transporter 0.0033 0.0173 0.173
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0399 0.0388
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0423 0.282
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0163 0.0179
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.003 0.0033
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0511 0.1749
Echinococcus multilocularis geminin 0.0171 0.1567 0.1836
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.004
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Chlamydia trachomatis lysine--tRNA ligase 0.0053 0.0371 0.2465
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0163 0.0179
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0019 0.003 0.0102
Schistosoma mansoni sugar transporter 0.0033 0.0173 0.0241
Echinococcus multilocularis solute carrier family 22 0.0033 0.0173 0.0191
Brugia malayi hypothetical protein 0.0033 0.0173 0.0375
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.011 0.0946 0.3239
Brugia malayi Bromodomain containing protein 0.004 0.0245 0.054
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.003 0.0021
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0102 0.0141
Trichomonas vaginalis myo-inositol transporter, putative 0.0033 0.0173 0.0657
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1567 0.6317
Giardia lamblia GTOR 0.0019 0.003 0.0194
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0511 0.0695
Plasmodium vivax vivapain-2 0.0018 0.0015 0.0004
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0511 0.1151
Chlamydia trachomatis proline--tRNA ligase 0.0025 0.009 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0579 0.2304
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0109 0.0373
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0104 0.0883 0.1213
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0423 0.2836
Echinococcus multilocularis zinc finger protein 0.0021 0.0046 0.004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0155 0.0216
Loa Loa (eye worm) hypothetical protein 0.0045 0.0292 0.0636
Brugia malayi Thioredoxin reductase 0.005 0.0341 0.076
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0317 0.036
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0162 0.1469 1
Trypanosoma brucei metacaspase MCA3 0.0081 0.0651 0.2229
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0012 0.004
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0019 0.003 0.0102
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0015 0.0004
Onchocerca volvulus 0.0032 0.0155 0.0322
Loa Loa (eye worm) hypothetical protein 0.0162 0.1469 0.3346
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0012 0.004
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0072 0.0567 0.1271
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0083 0.0674 0.2306
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0173 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Echinococcus granulosus General substrate transporter 0.0204 0.1893 0.2619
Brugia malayi Pre-SET motif family protein 0.0032 0.0155 0.0333
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0869 0.1965
Trypanosoma brucei glucose transporter, putative 0.0074 0.0579 0.1982
Brugia malayi hypothetical protein 0.0033 0.0173 0.0375
Loa Loa (eye worm) hypothetical protein 0.0102 0.0869 0.1965
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0109 0.0395
Brugia malayi Sugar transporter family protein 0.0237 0.2229 0.5102
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0651 0.064
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0946 0.3796
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0143 0.0184
Loa Loa (eye worm) runx1 0.0056 0.0404 0.0895
Toxoplasma gondii cathepsin CPL 0.0018 0.0015 0.0006
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0074 0.0579 0.0569
Loa Loa (eye worm) hypothetical protein 0.007 0.0542 0.1213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Trypanosoma cruzi hexose transporter, putative 0.004 0.0242 0.083
Brugia malayi MAP kinase sur-1 0.011 0.0946 0.2152
Toxoplasma gondii lysine-tRNA ligase 0.0053 0.0371 0.0545
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Trypanosoma brucei glucose transporter, putative 0.0074 0.0579 0.1982
Schistosoma mansoni protein kinase 0.0074 0.0579 0.0805
Brugia malayi hypothetical protein 0.0033 0.0173 0.0375
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0106 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Trypanosoma brucei glucose transporter, putative 0.0074 0.0579 0.1982
Schistosoma mansoni hypothetical protein 0.0032 0.0163 0.0227
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0987 0.6727
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0012 0.0016
Brugia malayi hypothetical protein 0.0448 0.4359 1
Plasmodium falciparum glutathione reductase 0.005 0.0341 0.033
Plasmodium falciparum calcium-dependent protein kinase 4 0.0074 0.0579 0.0569
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0567 0.2257
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Plasmodium vivax CDK-related protein kinase 6, putative 0.1007 1 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0019 0.0008
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0083 0.0674 0.2306
Plasmodium vivax lysine--tRNA ligase, putative 0.0053 0.0371 0.036
Echinococcus multilocularis GPCR, family 2 0.0032 0.0163 0.0179
Leishmania major mitochondrial DNA polymerase beta 0.0306 0.2921 1
Trypanosoma cruzi metacaspase, putative 0.0081 0.0651 0.2229
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1567 0.6317
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0015 0.0016
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0019 0.0026
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.003 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0517 0.177
Trichomonas vaginalis sugar transporter, putative 0.0074 0.0579 0.2304
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0071 0.0555 0.2205
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0384 0.3712 0.5612
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0106 0.0362
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0083 0.0674 0.1004
Leishmania major glucose transporter/membrane transporter D2, putative 0.0074 0.0579 0.1982
Onchocerca volvulus 0.0033 0.0173 0.0363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0173 0.0593
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0081 0.0651 0.097
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0511 0.059
Trypanosoma cruzi hexose transporter, putative 0.0074 0.0579 0.1982
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0271 0.0926
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0106 0.0907 0.6175
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0071 0.0555 0.0771
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0015 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.011 0.0946 0.3239
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.022 0.029
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Onchocerca volvulus 0.0033 0.0173 0.0363
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.003 0.0102
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0077 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0517 0.177
Echinococcus multilocularis solute carrier family 22 0.0033 0.0173 0.0191
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0511 0.1141
Loa Loa (eye worm) sugar transporter 0.0237 0.2229 0.5096
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0077 0.0107
Toxoplasma gondii protein kinase, putative 0.0671 0.6606 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.003 0.0025
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0053
Trypanosoma brucei glucose transporter 2A 0.0074 0.0579 0.1982
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.003 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0109 0.0395
Schistosoma mansoni protein kinase 0.0074 0.0579 0.0805
Toxoplasma gondii hypothetical protein 0.0049 0.0334 0.0489
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0019 0.003 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0651 0.2597
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0074 0.0579 0.1298
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.1115 0.7613
Schistosoma mansoni glucose transport protein 0.0237 0.2229 0.3099
Echinococcus granulosus peptidase Clp S14 family 0.0106 0.0907 0.1246
Loa Loa (eye worm) hypothetical protein 0.0071 0.0555 0.1241
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0567 0.2257
Leishmania major hypothetical protein, conserved 0.0027 0.0106 0.0362
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0071 0.0555 0.0771
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0534 0.0743
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0162 0.1469 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0155 0.0218
Echinococcus multilocularis lysosomal alpha glucosidase 0.0326 0.3129 0.368
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0069 0.0534 0.2123
Onchocerca volvulus 0.0189 0.1741 0.3972
Leishmania major glucose transporter, lmgt2 0.0074 0.0579 0.1982
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0946 0.3239
Loa Loa (eye worm) hypothetical protein 0.0043 0.0271 0.0589
Leishmania major cathepsin L-like protease 0.0067 0.0517 0.177
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0261 0.2474 0.5659
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0071 0.0555 0.0641
Loa Loa (eye worm) hypothetical protein 0.0041 0.0246 0.0531
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2474 1
Brugia malayi Cell death protein 3 precursor 0.0206 0.1916 0.4381
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0163 0.0211
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.1296 0.4439
Brugia malayi major facilitator superfamily protein 0.0033 0.0173 0.0375
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0019 0.003 0.0254
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0023 0.0065 0.0221
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.004
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0162 0.1469 0.1459
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0383 0.0847
Brugia malayi Probable ClpP-like protease 0.0162 0.1469 0.3354
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0015 0.0004
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0102 0.0348
Brugia malayi major facilitator superfamily protein 0.0033 0.0173 0.0375
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0237 0.2229 0.2618
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0237 0.2229 0.3088
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.2227 0.5091
Echinococcus multilocularis neuropeptide s receptor 0.049 0.4783 0.5633
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0857 0.8482 1
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0053
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0511 0.071
Trypanosoma cruzi metacaspase, putative 0.0081 0.0651 0.2229
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.004
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2474 1
Entamoeba histolytica protein kinase, putative 0.0074 0.0579 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0081 0.0651 0.1473
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0511 0.1749
Entamoeba histolytica protein kinase, putative 0.0074 0.0579 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0019 0.003 0.0102
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.011 0.0946 0.3239
Brugia malayi Melibiase family protein 0.0069 0.0534 0.1205
Onchocerca volvulus 0.0033 0.0173 0.0363
Echinococcus granulosus solute carrier family 22 0.0033 0.0173 0.0225
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0154 0.1394 0.1632
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0015 0.0021
Onchocerca volvulus Cell death protein 3 homolog 0.0206 0.1916 0.4375
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Loa Loa (eye worm) hypothetical protein 0.0027 0.0109 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0106 0.0907 0.5229
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0053
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0317 0.044
Echinococcus multilocularis General substrate transporter 0.0204 0.1893 0.2221
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0651 0.2597
Leishmania major glucose transporter, lmgt3 0.0074 0.0579 0.1982
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0033 0.0173 0.1115
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0987 0.5908
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0173 0.0657
Echinococcus multilocularis synaptic vesicle 2 protein 0.0033 0.0173 0.0191
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0317 0.0705
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0074 0.0579 0.067
Echinococcus multilocularis peptidase Clp (S14 family) 0.0106 0.0907 0.1057
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Plasmodium falciparum metacaspase 1 0.0081 0.0651 0.064
Onchocerca volvulus 0.0033 0.0173 0.0363
Onchocerca volvulus Glucosylceramidase homolog 0.0171 0.1567 0.3572
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0341 0.0389
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0227 0.03
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1567 0.6317
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0579 0.2305
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0015 0.0005
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0074 0.0579 0.1983
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0015 0.0005
Echinococcus multilocularis neutral alpha glucosidase AB 0.0072 0.0567 0.0656
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0317 0.044
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0109 0.0395
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0109 0.0395
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0071 0.0555 0.9566
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0163 0.0352
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0423 0.1447
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0019 0.0026
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0227 0.0254
Brugia malayi Muscleblind-like protein 0.0155 0.1404 0.3205
Trypanosoma brucei glucosidase, putative 0.0072 0.0567 0.1943
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0012 0.004
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0012 0.004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0083 0.0674 0.2306
Echinococcus multilocularis solute carrier family 22 0.0033 0.0173 0.0191
Trypanosoma brucei trypanothione reductase 0.005 0.0341 0.1168
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0102 0.0348
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0371 0.1272
Brugia malayi Glycosyl hydrolases family 31 protein 0.0072 0.0567 0.1281
Brugia malayi Sugar transporter family protein 0.0033 0.0173 0.0375
Plasmodium falciparum mitogen-activated protein kinase 2 0.0384 0.3712 0.3705
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1567 0.6317
Toxoplasma gondii melibiase subfamily protein 0.0104 0.0883 0.1321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0163 0.0211
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0081 0.0651 0.097
Brugia malayi Sugar transporter family protein 0.0033 0.0173 0.0375
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0012
Onchocerca volvulus Putative transporter 0.0033 0.0173 0.0363
Trypanosoma brucei glucose transporter 1E 0.0074 0.0579 0.1982
Loa Loa (eye worm) hypothetical protein 0.0155 0.1404 0.3197
Plasmodium vivax metacaspase 1, putative 0.0081 0.0651 0.064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Plasmodium falciparum metacaspase-like protein 0.0081 0.0651 0.064
Onchocerca volvulus 0.0033 0.0173 0.0363
Schistosoma mansoni hypothetical protein 0.0032 0.0163 0.0227
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0869 0.1974
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0074 0.0579 0.079
Giardia lamblia Kinase, CMGC MAPK 0.011 0.0946 1
Schistosoma mansoni hypothetical protein 0.007 0.0542 0.0754
Echinococcus granulosus caspase 2 0.0206 0.1916 0.2651
Trypanosoma brucei glucose transporter, putative 0.0074 0.0579 0.1982
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2474 1
Schistosoma mansoni hypothetical protein 0.0032 0.0163 0.0227
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Loa Loa (eye worm) hypothetical protein 0.0125 0.1102 0.25
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Onchocerca volvulus 0.0033 0.0173 0.0363
Brugia malayi hypothetical protein 0.0125 0.1102 0.2509
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Loa Loa (eye worm) hypothetical protein 0.0071 0.0555 0.1241
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.166 0.6696
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.1296 0.4439
Echinococcus multilocularis cysteine protease 0.0018 0.0015 0.0005
Trichomonas vaginalis glucose transporter, putative 0.0074 0.0579 0.2304
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Schistosoma mansoni hypothetical protein 0.0237 0.2229 0.3099
Trypanosoma brucei THT1 - hexose transporter, putative 0.0074 0.0579 0.1982
Echinococcus granulosus calcium dependent protein kinase 0.0068 0.0524 0.0714
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.004
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0237 0.2229 0.2618
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0306 0.2921 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0077 0.0091
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0423 0.0485
Echinococcus granulosus geminin 0.0171 0.1567 0.2166
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0579 0.0805
Schistosoma mansoni protein kinase 0.0074 0.0579 0.0805
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0104 0.0883 0.1028
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0883 0.1227
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0015 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0237 0.2229 0.2618
Trypanosoma brucei glucose transporter, putative 0.0074 0.0579 0.1982
Schistosoma mansoni hypothetical protein 0.0022 0.0057 0.0079
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0083 0.0674 0.2306
Trypanosoma cruzi hexose transporter 0.0074 0.0579 0.1982
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trypanosoma cruzi glucose transporter, putative 0.0033 0.0173 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0173 0.0657
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0015 0.0005
Onchocerca volvulus 0.0033 0.0173 0.0363
Trypanosoma cruzi hexose transporter, putative 0.0074 0.0579 0.1982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0237 0.2229 0.3088
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0083 0.0674 0.2306
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0074 0.0579 0.067
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0946 0.3796
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0384 0.3712 0.3705
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0074 0.0579 0.0861
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0102 0.0125
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trichomonas vaginalis sugar transport protein, putative 0.0033 0.0173 0.0657
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0109 0.0373
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0106 0.0362
Leishmania major protein kinase, putative 0.0074 0.0579 0.1983
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0106 0.0362
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0162 0.1469 0.2029
Trichomonas vaginalis conserved hypothetical protein 0.0237 0.2229 0.9007
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0511 0.1749
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0012 0.004
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0012 0.004
Trypanosoma brucei metacaspase 5, putative 0.0081 0.0651 0.2229
Trichomonas vaginalis glucose transporter, putative 0.0074 0.0579 0.2304
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0033 0.0173 0.1109
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.004
Leishmania major lysyl-tRNA synthetase, putative 0.0053 0.0371 0.127
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0106 0.0094
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0012
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0162 0.1469 0.1721
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0511 0.1749
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0987 0.6727
Echinococcus multilocularis cysteine protease 0.0018 0.0015 0.0005
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0423 0.0948
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Mycobacterium tuberculosis Probable reductase 0.0114 0.0987 0.6727
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0567 0.1943
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2474 1
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Plasmodium falciparum calcium-dependent protein kinase 5 0.0074 0.0579 0.0569
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0261 0.2474 0.5664
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.166 0.6696
Echinococcus granulosus solute carrier family 22 0.0033 0.0173 0.0225
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0306 0.2921 1
Echinococcus granulosus solute carrier family 22 0.0033 0.0173 0.0225
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0542 0.1223
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.011 0.0946 0.3239
Onchocerca volvulus 0.0033 0.0173 0.0363
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0341 0.0459
Echinococcus granulosus apoptotic protease activating factor 1 0.0125 0.1102 0.1518
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0053
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Brugia malayi PHD-finger family protein 0.0026 0.0102 0.0212
Echinococcus granulosus mitogen activated protein kinase 0.011 0.0946 0.1301
Entamoeba histolytica hypothetical protein 0.0026 0.0102 0.1531
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Loa Loa (eye worm) hypothetical protein 0.0075 0.0591 0.1325
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0012 0.004
Toxoplasma gondii hypothetical protein 0.0056 0.0399 0.0588
Brugia malayi Glycosyl hydrolases family 31 protein 0.0326 0.3129 0.717
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0053
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.011 0.0946 0.3239
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0511 0.8791
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0106 0.0143
Treponema pallidum prolyl-tRNA synthetase 0.0025 0.009 0.0541
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.003 0.0041
Onchocerca volvulus 0.0033 0.0173 0.0363
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0071 0.0555 0.0756
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0033 0.0173 0.1109
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0015 0.0021
Echinococcus granulosus zinc finger protein 0.0021 0.0046 0.0047
Onchocerca volvulus 0.0033 0.0173 0.0363
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0109 0.0215
Trichomonas vaginalis glucose transporter, putative 0.0033 0.0173 0.0657
Brugia malayi Cam kinase protein 1 0.0074 0.0579 0.1308
Plasmodium falciparum proline--tRNA ligase 0.0083 0.0674 0.0663
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0081 0.0651 0.0905
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.003 0.0102
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0045 0.029 0.1923
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0074 0.0579 0.079
Trichomonas vaginalis set domain proteins, putative 0.025 0.2362 0.9547
Echinococcus multilocularis solute carrier family 22 0.0033 0.0173 0.0191
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Loa Loa (eye worm) major facilitator superfamily transporter 0.0033 0.0173 0.0363
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0019 0.003 0.0102
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.003 0.0103
Echinococcus multilocularis microtubule associated protein 2 0.0729 0.7194 0.8479
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0074 0.0579 0.067
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1567 0.6317
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.022 0.0246
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0162 0.1469 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0015 0.0012
Plasmodium vivax calcium-dependent protein kinase, putative 0.0074 0.0579 0.0569
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0306 0.2921 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0155 0.0216
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.011 0.0946 0.1417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Schistosoma mansoni alpha-glucosidase 0.0281 0.267 0.3712
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.003 0.0102
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0033 0.0173 0.0593
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0109 0.0395
Schistosoma mansoni hypothetical protein 0.0032 0.0163 0.0227
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0162 0.1469 0.1459
Echinococcus multilocularis caspase 0.0154 0.1394 0.1632
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0341 0.1168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Echinococcus granulosus synaptic vesicle 2 protein 0.0033 0.0173 0.0225
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0567 0.9792
Schistosoma mansoni lysyl-tRNA synthetase 0.0053 0.0371 0.0516
Schistosoma mansoni caspase-3 (C14 family) 0.0154 0.1394 0.1937
Leishmania major phosphatidylinositol 3-kinase, putative 0.0019 0.003 0.0102
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0162 0.1469 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0033 0.0173 0.0363
Echinococcus multilocularis apoptotic protease activating factor 1 0.0125 0.1102 0.1287
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0317 0.036
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0045 0.029 0.1923
Schistosoma mansoni sugar transporter 0.0033 0.0173 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0651 0.2597
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0337 0.0468
Toxoplasma gondii facilitative glucose transporter GT1 0.0237 0.2229 0.3363
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0012 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0567 0.2257
Schistosoma mansoni zinc finger protein 0.0021 0.0046 0.0063
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0012 0.004
Schistosoma mansoni sugar transporter 0.0033 0.0173 0.0241
Echinococcus granulosus neutral alpha glucosidase AB 0.0072 0.0567 0.0774
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0015 0.0005
Brugia malayi follicle stimulating hormone receptor 0.0237 0.2227 0.5097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0081 0.0651 0.2597
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.1296 0.4439
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Loa Loa (eye worm) hypothetical protein 0.0058 0.042 0.0931
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Brugia malayi Major Facilitator Superfamily protein 0.0033 0.0173 0.0375
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0102 0.021
Echinococcus granulosus neuropeptide receptor A26 0.049 0.4783 0.6643
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0399 0.266
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.003 0.0041
Echinococcus granulosus caspase 3 0.0074 0.0579 0.0791
Trypanosoma brucei metacaspase 0.0081 0.0651 0.2229
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0019 0.003 0.0254
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 0.0053 0.0371 0.0818
Loa Loa (eye worm) hypothetical protein 0.0023 0.0065 0.0113
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Toxoplasma gondii sugar transporter ST3 0.0033 0.0173 0.0245
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Loa Loa (eye worm) hypothetical protein 0.0155 0.1404 0.3197
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Trypanosoma cruzi hexose transporter, putative 0.0074 0.0579 0.1982
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Onchocerca volvulus 0.0033 0.0173 0.0363
Brugia malayi Bromodomain containing protein 0.0079 0.0636 0.144
Echinococcus multilocularis caspase 8 0.0081 0.0651 0.0755
Schistosoma mansoni alpha-glucosidase 0.0281 0.267 0.3712
Trichomonas vaginalis sugar transporter, putative 0.0033 0.0173 0.0657
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0025 0.009 0.0541
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0237 0.2229 0.3088
Brugia malayi lysyl-tRNA synthetase 0.0053 0.0371 0.0829
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0019 0.003 0.0102
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0071 0.0555 0.1251
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0567 0.2257
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0883 0.1227
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.004
Giardia lamblia Sugar-proton symporter 0.0033 0.0173 0.173
Trypanosoma brucei glucose transporter, putative 0.0074 0.0579 0.1982
Plasmodium falciparum hexose transporter 0.0237 0.2229 0.222
Plasmodium falciparum thioredoxin reductase 0.005 0.0341 0.033
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0056 0.0399 0.0923
Schistosoma mansoni hypothetical protein 0.0171 0.1567 0.2178
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.004
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0109 0.0373
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.004
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0162 0.1469 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.003 0.0074
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0071 0.0555 0.1251
Mycobacterium ulcerans sugar transporter 0.0033 0.0173 0.1109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0517 0.177
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0458 0.1568
Toxoplasma gondii thioredoxin reductase 0.005 0.0341 0.05
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0016
Trypanosoma cruzi metacaspase 5, putative 0.0081 0.0651 0.2229
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0106 0.0907 0.6175
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0109 0.0395
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0025 0.0023
Plasmodium falciparum protein kinase 7 0.0671 0.6606 0.6602
Echinococcus multilocularis caspase 3 0.0074 0.0579 0.067
Loa Loa (eye worm) major facilitator superfamily transporter 0.0033 0.0173 0.0363
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0473 0.0545
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0033 0.0173 0.1109

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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