Detailed information for compound 800902

Basic information

Technical information
  • TDR Targets ID: 800902
  • Name: 4-bromo-N-[2-(2-methoxyphenoxy)ethyl]benzamid e
  • MW: 350.207 | Formula: C16H16BrNO3
  • H donors: 1 H acceptors: 1 LogP: 3.53 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1OCCNC(=O)c1ccc(cc1)Br
  • InChi: 1S/C16H16BrNO3/c1-20-14-4-2-3-5-15(14)21-11-10-18-16(19)12-6-8-13(17)9-7-12/h2-9H,10-11H2,1H3,(H,18,19)
  • InChiKey: ZTWDLKVBDPARED-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • CBMicro_037501
  • BIM-0037607.P001
  • A2703/0115000
  • ZINC02176440
  • EU-0053093
  • 4-Bromo-N-[2-(2-methoxy-phenoxy)-ethyl]-benzamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Homo sapiens heat shock protein 90kDa alpha (cytosolic), class A member 1 Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Plasmodium falciparum heat shock protein 90, putative Starlite/ChEMBL No references
Homo sapiens Niemann-Pick disease, type C1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus heat shock protein heat shock protein 90 alpha Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Grp94/Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax heat shock protein, putative Get druggable targets OG5_144951 All targets in OG5_144951
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-alpha, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis hsp90 protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense heat shock protein 83,heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Endoplasmin precursor Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Cryptosporidium parvum Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock 90 kDa protein homolog Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Toxoplasma gondii heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium yoelii heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Babesia bovis heat shock protein 90 Get druggable targets OG5_144951 All targets in OG5_144951
Leishmania donovani heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K04079 molecular chaperone HtpG, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock protein 83 Get druggable targets OG5_144951 All targets in OG5_144951
Schistosoma mansoni niemann-pick C1 (NPC1) Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania mexicana lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus Niemann Pick C1 protein Get druggable targets OG5_128206 All targets in OG5_128206
Neospora caninum HSP90, related Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis expressed conserved protein Get druggable targets OG5_128206 All targets in OG5_128206
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128206 All targets in OG5_128206
Plasmodium knowlesi endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K09487 heat shock protein 90kDa beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Cryptosporidium hominis heat shock protein 83 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans potential membrane protein similar to S. cerevisiae NCR1 (YPL006W) and human NPC1 late endosomal protein involved in sterol home Get druggable targets OG5_128206 All targets in OG5_128206
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Theileria parva heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans hypothetical protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii putative heat shock protein 81-2 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Neospora caninum heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum HSP90-like protein, related Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum IPR003367,Thrombospondin type 3 repeat;IPR002048,Calcium-binding EF-hand,domain-containing Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum Niemann-Pick C1 protein precursor, putative Get druggable targets OG5_128206 All targets in OG5_128206
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica Niemann-Pick C1 protein, putative Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K07003 Niemann Pick type C1, putative Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax heat shock protein 86, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii Hsp90 domain-containing protein Get druggable targets OG5_144951 All targets in OG5_144951
Theileria parva heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_144951 All targets in OG5_144951
Trypanosoma brucei Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein HSP90 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Niemann-Pick C1 protein precursor Get druggable targets OG5_128206 All targets in OG5_128206
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Treponema pallidum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Schistosoma mansoni heat shock protein 0.0055 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0052 0.0383 0.057
Loa Loa (eye worm) hypothetical protein 0.0175 0.1462 0.2176
Brugia malayi EGF-like domain containing protein 0.0025 0.0151 0.0226
Loa Loa (eye worm) hypothetical protein 0.0776 0.6717 1
Trichomonas vaginalis endoplasmin, putative 0.004 0.0281 0.2325
Toxoplasma gondii transitional endoplasmic reticulum ATPase, putative 0.0088 0.0696 0.3945
Onchocerca volvulus 0.0025 0.0151 0.0887
Loa Loa (eye worm) hypothetical protein 0.0086 0.068 0.1013
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Brugia malayi hypothetical protein 0.0012 0.0034 0.0051
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0012 0.0038 0.0038
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0052 0.0384 1
Trypanosoma cruzi Sphingosine kinase 0.0012 0.0038 0.0056
Mycobacterium ulcerans diacylglycerol kinase 0.0012 0.0038 0.014
Schistosoma mansoni notch 0.0025 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Trichomonas vaginalis sphingosine kinase, putative 0.0012 0.0038 0.0311
Schistosoma mansoni cpg binding protein 0.003 0.0189 0.0189
Schistosoma mansoni heat shock protein 0.0037 0.0251 0.0251
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0151 0.0226
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0012 0.0038 0.0038
Loa Loa (eye worm) ceramide kinase 0.0012 0.0038 0.0056
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0021 0.0021
Brugia malayi valosin containing protein 0.0086 0.068 0.1013
Schistosoma mansoni diacylglycerol kinase theta 0.0012 0.0038 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0413 0.0413
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0035 0.0233 0.1923
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.097 0.1443
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Echinococcus granulosus transitional endoplasmic reticulum atpase 0.0146 0.1209 0.1209
Loa Loa (eye worm) notch protein 0.0025 0.0151 0.0226
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.001 0.001
Brugia malayi EGF-like domain containing protein 0.0025 0.0151 0.0226
Brugia malayi Animal haem peroxidase family protein 0.0078 0.0615 0.0916
Schistosoma mansoni thyroid hormone receptor 0.001 0.0021 0.0021
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0139 0.1144 0.1144
Trypanosoma cruzi heat shock protein 90, putative 0.0055 0.0414 0.0616
Leishmania major diacylglycerol kinase, putative 0.0012 0.0038 0.0056
Brugia malayi Peroxidasin 0.0078 0.0615 0.0916
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0025 0.0151 0.0151
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0021 0.0021
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0021 0.0021
Echinococcus granulosus nibrin 0.0012 0.0034 0.0034
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0584 0.504 1
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0052 0.0384 0.1429
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0051
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0414 0.0616
Trypanosoma brucei heat shock protein, putative 0.0055 0.0414 0.0616
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0037 0.0251 0.1472
Trichomonas vaginalis spermatogenesis associated factor, putative 0.0146 0.1209 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0376 0.056
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0397 0.3399 0.506
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0021 0.0032
Onchocerca volvulus 0.0078 0.0615 0.3602
Loa Loa (eye worm) animal heme peroxidase 0.0078 0.0615 0.0916
Echinococcus granulosus Polycystic kidney disease protein 0.0203 0.1708 0.1708
Schistosoma mansoni hypothetical protein 0.0025 0.0151 0.0151
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0021 0.0021
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0189 0.0282
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0034 0.0282
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Plasmodium falciparum replication factor C subunit 1, putative 0.0012 0.0034 0.0193
Entamoeba histolytica hypothetical protein 0.0043 0.031 0.1153
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0021 0.0032
Brugia malayi EGF-like domain containing protein 0.0025 0.0151 0.0226
Echinococcus granulosus Diacylglycerol kinase theta 0.0012 0.0038 0.0038
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0187 0.1565 0.1565
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.0986 0.0986
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0012 0.0038 0.0056
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0012 0.0038 0.0038
Brugia malayi Protein kinase domain containing protein 0.0053 0.0397 0.0591
Loa Loa (eye worm) hypothetical protein 0.0052 0.0383 0.057
Trypanosoma cruzi diacylglycerol kinase, putative 0.0012 0.0038 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0021 0.0032
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0052 0.0383 0.0383
Schistosoma mansoni hypothetical protein 0.0043 0.031 0.031
Schistosoma mansoni nuclear hormone receptor 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0203 0.1708 0.2543
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0021 0.0032
Brugia malayi Animal haem peroxidase family protein 0.0078 0.0615 0.0916
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0414 0.1539
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Onchocerca volvulus Chorion peroxidase homolog 0.0078 0.0615 0.3602
Echinococcus multilocularis expressed conserved protein 0.0112 0.0907 0.0907
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0021 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0021 0.0032
Schistosoma mansoni hypothetical protein 0.0049 0.036 0.036
Schistosoma mansoni hypothetical protein 0.0012 0.0038 0.0038
Loa Loa (eye worm) doublecortin family protein 0.0203 0.1708 0.2543
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.097 0.097
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0413 0.0615
Plasmodium vivax diacylglycerol kinase, putative 0.0012 0.0038 0.0075
Entamoeba histolytica diacylglycerol kinase, putative 0.0012 0.0038 0.014
Echinococcus multilocularis RUN 0.0203 0.1708 0.1708
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0414 0.0616
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0021 0.0021
Brugia malayi Hsp90 protein 0.0037 0.0251 0.0374
Mycobacterium tuberculosis Conserved protein 0.0316 0.2689 1
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0034 0.0034
Schistosoma mansoni cpg binding protein 0.0031 0.0204 0.0204
Echinococcus multilocularis cpg binding protein 0.0031 0.0204 0.0204
Schistosoma mansoni loxhd1 0.0203 0.1708 0.1708
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0414 0.0616
Chlamydia trachomatis DNA ligase 0.0012 0.0034 1
Brugia malayi notch-like transmembrane receptor 0.0025 0.0151 0.0226
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0053 0.0397 0.0397
Brugia malayi probable protein kinase 0.0177 0.1476 0.2197
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0316 0.2689 0.4003
Loa Loa (eye worm) hypothetical protein 0.0203 0.1708 0.2543
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0032
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0034 0.0193
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Leishmania major heat shock protein, putative 0.0037 0.0251 0.0374
Echinococcus multilocularis Polycystic kidney disease protein 0.0203 0.1708 0.1708
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0034 0.0282
Echinococcus granulosus protein jagged 1 0.0025 0.0151 0.0151
Trypanosoma cruzi Sphingosine kinase 0.0012 0.0038 0.0056
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0021 0.0021
Echinococcus granulosus neurogenic locus notch protein 4 0.0025 0.0151 0.0151
Brugia malayi DKFZp564C0469 protein 0.0012 0.0034 0.0051
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0052 0.0383 0.0383
Trypanosoma cruzi Valosin-containing protein, putative 0.0139 0.1144 0.1702
Brugia malayi hypothetical protein 0.0043 0.031 0.0461
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0053 0.0397 0.0397
Schistosoma mansoni microtubule-associated protein tau 0.0712 0.6158 0.6158
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0413 0.0615
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0421 0.2388
Trypanosoma brucei Valosin-containing protein 0.0139 0.1144 0.1702
Brugia malayi nuclear receptor NHR-88 0.001 0.0021 0.0032
Echinococcus granulosus heat shock protein 90 0.0047 0.0344 0.0344
Onchocerca volvulus 0.0025 0.0151 0.0887
Trypanosoma cruzi heat shock protein, putative 0.0037 0.0251 0.0374
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0125 0.1023 0.1523
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0012 0.0034 0.0193
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0012 0.0038 0.0056
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0166 0.1378 0.8069
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0021 0.0032
Onchocerca volvulus 0.0012 0.0034 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.1378 0.1378
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0021 0.0032
Echinococcus multilocularis protein patched 0.0051 0.0376 0.0376
Entamoeba histolytica hypothetical protein 0.0043 0.031 0.1153
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Plasmodium falciparum LCCL domain-containing protein 0.0203 0.1708 0.9686
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0151 0.0151
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0413 0.0413
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0384 0.3177
Trypanosoma brucei Emopamil binding protein, putative 0.0148 0.1224 0.1822
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0021 0.0021
Brugia malayi heat shock protein 90 0.0055 0.0414 0.0616
Schistosoma mansoni vam6/vps39 related 0.0052 0.0383 0.0383
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0021 0.0021
Loa Loa (eye worm) heat shock protein 90 0.0055 0.0414 0.0616
Schistosoma mansoni protein kinase 0.0053 0.0397 0.0397
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0038 0.0311
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0034 0.0051
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0021 0.0032
Plasmodium falciparum heat shock protein 90, putative 0.0032 0.0211 0.1198
Plasmodium vivax multidomain scavenger receptor, putative 0.0203 0.1708 0.3389
Schistosoma mansoni endoplasmin 0.0055 0.0414 0.0414
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0052 0.0383 0.0383
Echinococcus granulosus heat shock protein 0.0055 0.0414 0.0414
Onchocerca volvulus Peroxidasin homolog 0.0078 0.0615 0.3602
Echinococcus granulosus endoplasmin 0.0052 0.0384 0.0384
Echinococcus granulosus dnaJ subfamily B 0.0422 0.3622 0.3622
Trypanosoma brucei heat shock protein, putative 0.0055 0.0414 0.0616
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0776 0.6717 1
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.0061 0.0459 0.0459
Entamoeba histolytica diacylglycerol kinase, putative 0.0012 0.0038 0.014
Echinococcus multilocularis protein dispatched 1 0.0058 0.0439 0.0439
Echinococcus granulosus neurogenic locus protein delta 0.0025 0.0151 0.0151
Loa Loa (eye worm) endoplasmin 0.0055 0.0414 0.0616
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0012 0.0034 0.0127
Echinococcus multilocularis peroxidasin 0.0078 0.0615 0.0615
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Onchocerca volvulus 0.0148 0.1224 0.7164
Echinococcus multilocularis neurogenic locus notch protein 4 0.0025 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Brugia malayi Ceramide kinase 0.0012 0.0038 0.0056
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0021 0.0021
Mycobacterium tuberculosis Diacylglycerol kinase 0.0012 0.0038 0.014
Echinococcus multilocularis neural cadherin 0.0025 0.0151 0.0151
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0166 0.1378 0.2052
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0776 0.6717 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0034 0.0282
Brugia malayi Cadherin domain containing protein 0.0025 0.0151 0.0226
Brugia malayi Animal haem peroxidase family protein 0.0078 0.0615 0.0916
Brugia malayi Pax transcription activation domain interacting protein 0.0012 0.0034 0.0051
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0166 0.1378 0.2052
Schistosoma mansoni diacylglycerol kinase theta 0.0012 0.0038 0.0038
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0021 0.0021
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0376 0.0376
Mycobacterium ulcerans heat shock protein 90 0.0052 0.0384 0.1429
Entamoeba histolytica diacylglycerol kinase, putative 0.0012 0.0038 0.014
Schistosoma mansoni notch 0.0025 0.0151 0.0151
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0021 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0021 0.0032
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0021 0.0125
Plasmodium vivax endoplasmin, putative 0.0055 0.0414 0.0821
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0053 0.0397 0.0591
Brugia malayi hypothetical protein 0.0012 0.0038 0.0056
Trichomonas vaginalis sphingosine kinase, putative 0.0012 0.0038 0.0311
Toxoplasma gondii diacylglycerol kinase, putative 0.0012 0.0038 0.0213
Giardia lamblia High cysteine protein 0.0025 0.0151 0.2177
Schistosoma mansoni slit 0.0025 0.0151 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0021 0.0032
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0148 0.1224 0.1822
Trypanosoma cruzi diacylglycerol kinase, putative 0.0012 0.0038 0.0056
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0146 0.1209 0.1209
Plasmodium vivax diacylglycerol kinase, putative 0.0012 0.0038 0.0075
Onchocerca volvulus Peroxidase homolog 0.0078 0.0615 0.3602
Toxoplasma gondii EGF family domain-containing protein 0.0025 0.0151 0.0859
Brugia malayi Animal haem peroxidase family protein 0.0078 0.0615 0.0916
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0032
Plasmodium falciparum heat shock protein 90 0.0055 0.0414 0.2347
Echinococcus multilocularis neurogenic locus protein delta 0.0025 0.0151 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0034 0.0282
Entamoeba histolytica transitional endoplasmic reticulum ATPase, putative 0.0139 0.1144 0.4253
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0021 0.0032
Echinococcus multilocularis fat cadherin tumor suppressor 0.0025 0.0151 0.0151
Schistosoma mansoni rap gtpase-activating protein 0.0052 0.0383 0.0383
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0038 0.0056
Trypanosoma brucei heat shock protein 84, putative 0.0037 0.0251 0.0374
Schistosoma mansoni hypothetical protein 0.0025 0.0151 0.0151
Schistosoma mansoni sphingoid long chain base kinase 0.0316 0.2689 0.2689
Brugia malayi Animal haem peroxidase family protein 0.0078 0.0615 0.0916
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0056
Schistosoma mansoni cell polarity protein 0.0025 0.0151 0.0151
Trypanosoma cruzi Emopamil binding protein, putative 0.0148 0.1224 0.1822
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Loa Loa (eye worm) animal heme peroxidase 0.0078 0.0615 0.0916
Schistosoma mansoni notch 0.0025 0.0151 0.0151
Echinococcus granulosus peroxidasin 0.0078 0.0615 0.0615
Schistosoma mansoni topbp1 0.0012 0.0034 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0397 0.0397
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0051
Loa Loa (eye worm) VCP protein 0.0061 0.0459 0.0684
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Brugia malayi Temporarily assigned gene name protein 59 0.0052 0.0383 0.057
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0012 0.0038 0.0056
Onchocerca volvulus Putative cubilin 0.0025 0.0151 0.0887
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0034 0.0282
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0021 0.0032
Trypanosoma brucei heat shock protein, putative 0.0055 0.0414 0.0616
Schistosoma mansoni heat shock protein 0.0055 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Schistosoma mansoni lipoxygenase 0.1152 1 1
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0012 0.0038 0.0311
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0151 0.0151
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0052 0.0383 0.0383
Schistosoma mansoni coup transcription factor 0.001 0.0021 0.0021
Onchocerca volvulus Peroxidasin homolog 0.0078 0.0615 0.3602
Toxoplasma gondii cell division protein CDC48CY 0.0146 0.1209 0.6858
Giardia lamblia AAA family ATPase 0.0088 0.0696 1
Leishmania major diacylglycerol kinase-like protein 0.0012 0.0038 0.0056
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0012 0.0034 0.0886
Treponema pallidum heat shock protein 90 0.0052 0.0384 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Loa Loa (eye worm) Notch2 0.0025 0.0151 0.0226
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0021 0.0032
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0241 0.2041 0.3038
Schistosoma mansoni protein kinase 0.0125 0.1023 0.1023
Loa Loa (eye worm) hypothetical protein 0.0052 0.0383 0.057
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0012 0.0038 0.0213
Schistosoma mansoni peroxidasin 0.0078 0.0615 0.0615
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0047 0.0344 0.0344
Echinococcus granulosus lipoxygenase domain containing protein 0.0203 0.1708 0.1708
Brugia malayi EGF-like domain containing protein 0.0025 0.0151 0.0226
Brugia malayi CHE-14 protein 0.0051 0.0376 0.056
Schistosoma mansoni rab6-interacting 0.0203 0.1708 0.1708
Trichomonas vaginalis heat shock protein, putative 0.0055 0.0414 0.3422
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0021 0.0021
Echinococcus multilocularis neurogenic locus protein delta 0.0025 0.0151 0.0151
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0012 0.0038 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0397 0.0397
Brugia malayi Eye-specific diacylglycerol kinase 0.0012 0.0038 0.0056
Echinococcus multilocularis ceramide kinase 0.0012 0.0038 0.0038
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0062 0.0477 0.0709
Loa Loa (eye worm) histone methyltransferase 0.0009 0.001 0.0015
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0037 0.0251 0.0251
Brugia malayi hypothetical protein 0.0078 0.0615 0.0916
Plasmodium falciparum cell division cycle protein 48 homologue, putative 0.0139 0.1144 0.6484
Leishmania major hypothetical protein, conserved 0.0012 0.0038 0.0056
Plasmodium falciparum heat shock protein 90, putative 0.021 0.1764 1
Echinococcus granulosus cpg binding protein 0.0031 0.0204 0.0204
Brugia malayi GCC2 and GCC3 family protein 0.0025 0.0151 0.0226
Echinococcus granulosus protein jagged 2 0.0025 0.0151 0.0151
Echinococcus granulosus microtubule associated protein 2 0.0712 0.6158 0.6158
Echinococcus granulosus lipoxygenase domain containing protein 0.0203 0.1708 0.1708
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Schistosoma mansoni hypothetical protein 0.0025 0.0151 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0021 0.0032
Schistosoma mansoni peroxidasin 0.0078 0.0615 0.0615
Schistosoma mansoni hypothetical protein 0.0049 0.036 0.036
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0053 0.0397 0.0397
Plasmodium vivax cell division cycle protein 48 homologue, putative 0.0139 0.1144 0.2269
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0422 0.3622 0.3622
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.0133 0.0198
Onchocerca volvulus 0.0025 0.0151 0.0887
Echinococcus granulosus ceramide kinase 0.0012 0.0038 0.0038
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0151 0.0226
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0148 0.1224 0.1822
Plasmodium falciparum endoplasmin, putative 0.004 0.0281 0.1595
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0021 0.0021
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0344 0.2844
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0051
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0053 0.0397 0.0397
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0052 0.0384 1
Echinococcus multilocularis heat shock protein 0.0055 0.0414 0.0414
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0384 0.3177
Trypanosoma brucei heat shock protein, putative 0.0055 0.0414 0.0616
Echinococcus multilocularis nibrin 0.0012 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Trypanosoma brucei Heat shock protein 83, putative 0.0055 0.0414 0.0616
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0053 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Loa Loa (eye worm) diacylglycerol kinase 2 0.0012 0.0038 0.0056
Echinococcus granulosus FTZ F1 alpha 0.001 0.0021 0.0021
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0012 0.0038 0.0056
Trypanosoma brucei heat shock protein, putative 0.0055 0.0414 0.0616
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0021 0.0021
Brugia malayi hypothetical protein 0.0012 0.0034 0.0051
Brugia malayi CXXC zinc finger family protein 0.003 0.0189 0.0282
Schistosoma mansoni notch 0.0025 0.0151 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0021 0.0032
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0021 0.0021
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0151 0.0151
Echinococcus multilocularis Diacylglycerol kinase theta 0.0012 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0037 0.0251 0.0251
Onchocerca volvulus 0.0025 0.0151 0.0887
Plasmodium falciparum diacylglycerol kinase, putative 0.0012 0.0038 0.0213
Echinococcus multilocularis fibropellin Ia 0.0025 0.0151 0.0151
Brugia malayi map kinase activated protein kinase protein 2 0.0187 0.1565 0.233
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0414 0.1539
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.097 0.3606
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0012 0.0038 0.0056
Loa Loa (eye worm) hypothetical protein 0.0051 0.0376 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0034 0.0282
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0021 0.0032
Onchocerca volvulus Neurogenic locus notch homolog 0.0025 0.0151 0.0887
Brugia malayi diacylglycerol kinase 0.0012 0.0038 0.0056
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Trypanosoma brucei heat shock protein, putative 0.0055 0.0414 0.0616
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0211 0.1747
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0034 0.0282
Schistosoma mansoni cpg binding protein 0.0031 0.0204 0.0204
Echinococcus granulosus protein kinase 0.0125 0.1023 0.1023
Schistosoma mansoni lipoxygenase 0.0786 0.6799 0.6799
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0021 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0021 0.0032
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Schistosoma mansoni hypothetical protein 0.0025 0.0151 0.0151
Brugia malayi Endoplasmin precursor 0.0055 0.0414 0.0616
Echinococcus granulosus Diacylglycerol kinase zeta 0.0012 0.0038 0.0038
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Echinococcus multilocularis heat shock protein 90 0.0047 0.0344 0.0344
Entamoeba histolytica diacylglycerol kinase, putative 0.0012 0.0038 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0376 0.3111
Schistosoma mansoni rab6-interacting 0.0203 0.1708 0.1708
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.097 0.097
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0151 0.0151
Schistosoma mansoni notch 0.0025 0.0151 0.0151
Brugia malayi Delta serrate ligand family protein 0.0025 0.0151 0.0226
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0413 0.0413
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0034 0.0051
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0053 0.0397 0.0397
Entamoeba histolytica hypothetical protein 0.0043 0.031 0.1153
Echinococcus multilocularis notch 0.0025 0.0151 0.0151
Brugia malayi EGF-like domain containing protein 0.0025 0.0151 0.0226
Echinococcus multilocularis sphingosine kinase 1 0.0316 0.2689 0.2689
Onchocerca volvulus 0.001 0.0021 0.0125
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0012 0.0038 0.0311
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0032
Mycobacterium ulcerans hypothetical protein 0.0316 0.2689 1
Toxoplasma gondii heat shock protein 75, putative 0.0037 0.0251 0.1426
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Trypanosoma brucei diacylglycerol kinase, putative 0.0012 0.0038 0.0056
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Echinococcus multilocularis heat shock protein 90 0.0055 0.0414 0.0414
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.1416 0.1416
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0151 0.0226
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0021 0.0032
Trypanosoma brucei C-8 sterol isomerase, putative 0.0776 0.6717 1
Plasmodium falciparum diacylglycerol kinase, putative 0.0012 0.0038 0.0213
Schistosoma mansoni hypothetical protein 0.0025 0.0151 0.0151
Echinococcus multilocularis protein jagged 1 0.0025 0.0151 0.0151
Entamoeba histolytica cdc48-like protein, putative 0.0139 0.1144 0.4253
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Trichomonas vaginalis heat shock protein, putative 0.004 0.0281 0.2325
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.1565 0.1565
Onchocerca volvulus 0.0203 0.1708 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0203 0.1708 0.1708
Plasmodium vivax cell division cycle ATPase, putative 0.0053 0.0393 0.078
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.0146 0.1209 0.1209
Brugia malayi diacylglycerol kinase 0.0012 0.0038 0.0056
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0034 0.0034
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.8491 0.8491
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0413 0.0413
Toxoplasma gondii Hsp90 domain-containing protein 0.021 0.1764 1
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0052 0.0383 0.057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0021 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0034 0.0051
Trichomonas vaginalis proteasome-activating nucleotidase, putative 0.0035 0.0233 0.1923
Echinococcus granulosus protein jagged 1 0.0025 0.0151 0.0151
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0344 0.0512
Entamoeba histolytica hypothetical protein 0.0043 0.031 0.1153
Echinococcus granulosus slit 2 protein 0.0025 0.0151 0.0151
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0021 0.0021
Trichomonas vaginalis diacylglycerol kinase, putative 0.0012 0.0038 0.0311
Onchocerca volvulus 0.0078 0.0615 0.3602
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0009 0.0014
Echinococcus granulosus Vam6:Vps39 protein 0.0052 0.0383 0.0383
Schistosoma mansoni polycystin 1-related 0.0203 0.1708 0.1708
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0051
Schistosoma mansoni hypothetical protein 0.0025 0.0151 0.0151
Leishmania major hypothetical protein, conserved 0.0012 0.0038 0.0056
Schistosoma mansoni patched 1 0.0051 0.0376 0.0376
Brugia malayi Muscle positioning protein 4 0.0025 0.0151 0.0226
Trypanosoma cruzi Heat shock protein 83, putative 0.0055 0.0414 0.0616
Echinococcus multilocularis microtubule associated protein 2 0.0712 0.6158 0.6158
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0025 0.0151 0.0887
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0034 0.0127
Schistosoma mansoni hypothetical protein 0.0052 0.0383 0.0383
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0021 0.0021
Trichomonas vaginalis diacylglycerol kinase, putative 0.0012 0.0038 0.0311
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0034 0.0282
Brugia malayi hypothetical protein 0.0203 0.1708 0.2543
Echinococcus granulosus protein jagged 2 0.0025 0.0151 0.0151
Entamoeba histolytica hypothetical protein, conserved 0.0316 0.2689 1
Onchocerca volvulus 0.003 0.0189 0.1108
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.048 0.048
Brugia malayi transitional endoplasmic reticulum ATPase TER94, putative 0.0061 0.0459 0.0684
Giardia lamblia Replication factor C, subunit 1 0.0012 0.0034 0.049
Onchocerca volvulus Slit protein homolog 0.0025 0.0151 0.0887
Trichomonas vaginalis bmru protein, putative 0.0012 0.0038 0.0311
Schistosoma mansoni hypothetical protein 0.0049 0.036 0.036
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0187 0.1565 0.1565
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0038 0.0056
Loa Loa (eye worm) heat shock protein 75 0.0037 0.0251 0.0374
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0037 0.0251 0.0935
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0021 0.0021
Echinococcus multilocularis lipoxygenase domain containing protein 0.0203 0.1708 0.1708
Echinococcus multilocularis protein jagged 2 0.0025 0.0151 0.0151
Brugia malayi Protein kinase domain containing protein 0.0166 0.1378 0.2052
Brugia malayi follicle stimulating hormone receptor 0.0241 0.2041 0.3038
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0021 0.0021
Trypanosoma cruzi Emopamil binding protein, putative 0.0148 0.1224 0.1822
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0175 0.1462 0.1462
Brugia malayi hypothetical protein 0.0203 0.1708 0.2543
Loa Loa (eye worm) blistered cuticle protein 3 0.0078 0.0615 0.0916
Schistosoma mansoni endoplasmin 0.0055 0.0414 0.0414
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0021 0.0021
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0012 0.0038 0.0038
Onchocerca volvulus 0.0203 0.1708 1
Onchocerca volvulus Dual oxidase homolog 0.0078 0.0615 0.3602
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Leishmania major C-8 sterol isomerase-like protein 0.0776 0.6717 1
Mycobacterium ulcerans ATPase 0.0088 0.0696 0.2587
Leishmania major Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog 0.0139 0.1144 0.1702
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0034 0.0282
Loa Loa (eye worm) hypothetical protein 0.0119 0.097 0.1443
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0166 0.1378 0.2052
Plasmodium vivax replication factor C subunit 1, putative 0.0012 0.0034 0.0068
Onchocerca volvulus 0.0025 0.0151 0.0887
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0012 0.0034 0.0051
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0025 0.0151 0.0226
Loa Loa (eye worm) animal heme peroxidase 0.0078 0.0615 0.0916
Toxoplasma gondii cell division protein CDC48AP 0.0088 0.0696 0.3945
Loa Loa (eye worm) vesicle-fusing ATPase 0.0086 0.068 0.1013
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.1416 0.1416
Onchocerca volvulus Transitional endoplasmic reticulum ATPase homolog 0.0146 0.1209 0.708
Onchocerca volvulus 0.0052 0.0383 0.2243
Echinococcus granulosus notch 0.0025 0.0151 0.0151
Toxoplasma gondii heat shock protein HSP90 0.0055 0.0414 0.2347
Brugia malayi vesicle-fusing ATPase 0.0086 0.068 0.1013
Trypanosoma cruzi FHA domain containing protein, putative 0.0012 0.0034 0.0051
Leishmania major sphingosine kinase A, B, putative 0.0012 0.0038 0.0056
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0012 0.0038 0.0311
Brugia malayi Cadherin domain containing protein 0.0025 0.0151 0.0226
Brugia malayi Diacylglycerol kinase protein 2 0.0012 0.0038 0.0056
Echinococcus granulosus delta-like protein 1 0.0025 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0032
Leishmania major hypothetical protein, conserved 0.0148 0.1224 0.1822
Echinococcus multilocularis slit 2 protein 0.0025 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.0203 0.1708 0.1708
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0032
Onchocerca volvulus 0.0012 0.0038 0.022
Echinococcus granulosus fibropellin Ia 0.0025 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.0049 0.036 0.036
Schistosoma mansoni hypothetical protein 0.0025 0.0151 0.0151
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0166 0.1378 0.1378
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0052 0.0384 0.0572
Echinococcus granulosus sphingosine kinase 1 0.0316 0.2689 0.2689
Trypanosoma brucei heat shock protein, putative 0.0055 0.0414 0.0616
Trypanosoma brucei heat shock protein, putative 0.0055 0.0414 0.0616
Echinococcus multilocularis protein jagged 1 0.0025 0.0151 0.0151
Brugia malayi EGF-like domain containing protein 0.0025 0.0151 0.0226
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0376 0.0376
Schistosoma mansoni topbp1 0.0012 0.0034 0.0034
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0414 0.0616
Giardia lamblia Grp94/Hsp90 0.0052 0.0384 0.5522
Plasmodium vivax heat shock protein, putative 0.021 0.1764 0.3499
Onchocerca volvulus 0.0078 0.0615 0.3602
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Entamoeba histolytica hypothetical protein 0.0012 0.0034 0.0127
Schistosoma mansoni protein kinase 0.0177 0.1476 0.1476
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0413 0.0413
Toxoplasma gondii heat shock protein 90, putative 0.0055 0.0414 0.2347
Echinococcus granulosus neural cadherin 0.0025 0.0151 0.0151
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1152 1 1
Onchocerca volvulus Ceramide kinase 1 homolog 0.0012 0.0038 0.022
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0376 0.0376
Brugia malayi steroid hormone receptor 0.001 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0344 0.0512
Onchocerca volvulus Peroxidase homolog 0.0078 0.0615 0.3602
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0187 0.1565 0.233
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0056
Schistosoma mansoni DNA ligase IV 0.0012 0.0034 0.0034
Schistosoma mansoni thyroid hormone receptor 0.001 0.0021 0.0021
Brugia malayi EGF-like domain containing protein 0.0025 0.0151 0.0226
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0032
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0166 0.1378 0.1378
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0052 0.0383 0.057
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0051
Plasmodium vivax heat shock protein 86, putative 0.0055 0.0414 0.0821
Trichomonas vaginalis bmru protein, putative 0.0012 0.0038 0.0311
Mycobacterium tuberculosis Putative conserved ATPase 0.0088 0.0696 0.2587
Schistosoma mansoni notch 0.0025 0.0151 0.0151
Schistosoma mansoni sphingosine kinase A B 0.0316 0.2689 0.2689
Leishmania major heat shock protein 83-1 0.0055 0.0414 0.0616
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0148 0.1224 0.1822
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0021 0.0021
Brugia malayi ecdysteroid receptor 0.001 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0021 0.0125
Brugia malayi Blistered cuticle protein 3 0.0078 0.0615 0.0916
Giardia lamblia Heat shock protein HSP 90-alpha 0.0055 0.0414 0.5949
Trypanosoma brucei Sphingosine kinase 0.0012 0.0038 0.0056
Echinococcus multilocularis endoplasmin 0.0052 0.0384 0.0384
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0414 0.0616
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0052 0.0383 0.057
Loa Loa (eye worm) animal heme peroxidase 0.0078 0.0615 0.0916
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.0344 0.4944
Echinococcus granulosus RUN 0.0203 0.1708 0.1708
Echinococcus multilocularis 0.0125 0.1023 0.1023
Schistosoma mansoni septate junction protein 0.0025 0.0151 0.0151
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0012 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0034 0.0282
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.031 0.031
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Echinococcus multilocularis dnaJ subfamily B 0.0422 0.3622 0.3622
Brugia malayi topoisomerase 0.0012 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0078 0.0615 0.0916
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Treponema pallidum DNA ligase (lig) 0.0012 0.0034 0.0886
Brugia malayi hypothetical protein 0.0052 0.0383 0.057
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0034 0.0034
Brugia malayi Doublecortin family protein 0.0203 0.1708 0.2543
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0061 0.0459 0.0459
Plasmodium vivax heat shock protein 90, putative 0.0037 0.0251 0.0499
Echinococcus granulosus heat shock protein 90 0.0055 0.0414 0.0414
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0021 0.0021
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.031 0.031
Brugia malayi nuclear hormone receptor 0.001 0.0021 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0056
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0051
Echinococcus granulosus expressed conserved protein 0.0112 0.0907 0.0907
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0151 0.0226
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0012 0.0034 0.0886

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) < 0.195 uM PUBCHEM_BIOASSAY: Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] ChEMBL. No reference
AC50 (functional) = 10.801 uM PUBCHEM_BIOASSAY: HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] ChEMBL. No reference
Potency (functional) 0.8913 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.3323 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for NPC1 Promoter Activators. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.6109 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.575 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 16.3535 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 23.9341 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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