Detailed information for compound 912451

Basic information

Technical information
  • TDR Targets ID: 912451
  • Name: N-[4-[(4-diethylamino-6-methylpyrimidin-2-yl) amino]phenyl]-3-fluorobenzenesulfonamide
  • MW: 429.511 | Formula: C21H24FN5O2S
  • H donors: 2 H acceptors: 4 LogP: 4.29 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(c1nc(Nc2ccc(cc2)NS(=O)(=O)c2cccc(c2)F)nc(c1)C)CC
  • InChi: 1S/C21H24FN5O2S/c1-4-27(5-2)20-13-15(3)23-21(25-20)24-17-9-11-18(12-10-17)26-30(28,29)19-8-6-7-16(22)14-19/h6-14,26H,4-5H2,1-3H3,(H,23,24,25)
  • InChiKey: IQGLBFHIKUNJST-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-[(4-diethylamino-6-methyl-pyrimidin-2-yl)amino]phenyl]-3-fluoro-benzenesulfonamide
  • N-[4-[(4-diethylamino-6-methyl-2-pyrimidinyl)amino]phenyl]-3-fluorobenzenesulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.01 0.0195
Giardia lamblia Hypothetical protein 0.003 0.0064 0.0869
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.003 0.0064 0.0003
Brugia malayi RNA binding protein 0.0336 0.1864 0.185
Mycobacterium tuberculosis Conserved protein 0.0114 0.0558 0.1206
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0229 0.0445
Loa Loa (eye worm) glutathione reductase 0.0086 0.0392 0.0386
Brugia malayi latrophilin 2 splice variant baaae 0.0314 0.1736 0.1722
Toxoplasma gondii CBS domain-containing protein 0.003 0.0064 0.0101
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0502 0.2846 1
Brugia malayi GMP reductase 0.0209 0.1117 0.1103
Leishmania major DNA polymerase eta, putative 0.0081 0.0363 0.1164
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0063 0.0097
Loa Loa (eye worm) hypothetical protein 0.005 0.0183 0.0177
Chlamydia trachomatis Mg++ transporter 0.003 0.0064 1
Mycobacterium ulcerans lipase LipD 0.0114 0.0558 0.186
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0523 0.0518
Echinococcus granulosus H:Cl exchange transporter 7 0.003 0.0064 0.0125
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0078 0.0152
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0055 0.0067
Mycobacterium tuberculosis Probable hydrolase 0.0114 0.0558 0.1206
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0063 0.0097
Loa Loa (eye worm) hypothetical protein 0.0039 0.0121 0.0115
Trichomonas vaginalis glucosylceramidase, putative 0.0551 0.3133 0.6798
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0523 0.1019
Brugia malayi Calcitonin receptor-like protein seb-1 0.0459 0.2592 0.2579
Loa Loa (eye worm) hypothetical protein 0.0052 0.0196 0.0191
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.072 0.1402
Trypanosoma cruzi trypanothione reductase, putative 0.0086 0.0392 0.1269
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.016 0.0312
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0063 0.0097
Schistosoma mansoni chloride channel protein 0.003 0.0064 0.0125
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0198 0.0385
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.006 0.0092
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.003 0.0064 0.0101
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.003 0.0064 0.0101
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0182 0.0959 0.0996
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0085 0.0177
Mycobacterium leprae conserved hypothetical protein 0.0114 0.0558 0.1777
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0063 0.0007
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0117 0.0577 0.06
Brugia malayi 6-phosphofructokinase 0.0108 0.0523 0.0507
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0081 0.0363 0.0706
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.003 0.0064 0.0101
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0101
Mycobacterium tuberculosis Conserved protein 0.003 0.0064 0.0003
Entamoeba histolytica hypothetical protein 0.0077 0.0342 0.6084
Leishmania major DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Brugia malayi loechrig isoform VII 0.003 0.0064 0.0047
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.016 0.0312
Trypanosoma brucei GMP reductase 0.0502 0.2846 1
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0502 0.2846 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0117 0.0577 0.1124
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.006 0.0086
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0063 0.0097
Loa Loa (eye worm) chloride channel protein 7 0.003 0.0064 0.0058
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0085 0.0089
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0523 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0198 0.0192
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0198 0.0205
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0114 0.0558 0.1206
Brugia malayi ancient conserved domain protein 2 0.003 0.0064 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0502 0.2846 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.01 0.0094
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0558 0.1102
Onchocerca volvulus 0.003 0.0064 0.0033
Leishmania major hypothetical protein, conserved 0.0114 0.0558 0.186
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.006 0.0086
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.003 0.0064 0.0125
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0209 0.1117 0.1103
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.003 0.0064 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0269 0.0264
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0145 0.0744 0.0772
Brugia malayi chloride channel protein 7 0.003 0.0064 0.0047
Schistosoma mansoni Smad4 0.0052 0.0196 0.0382
Brugia malayi PHD-finger family protein 0.0028 0.0055 0.0038
Loa Loa (eye worm) MH2 domain-containing protein 0.0052 0.0196 0.0191
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.072 0.0714
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0114 0.0558 0.1087
Loa Loa (eye worm) GMP reductase 0.0209 0.1117 0.1112
Mycobacterium ulcerans cystathionine beta-synthase 0.003 0.0064 0.0101
Onchocerca volvulus 0.0114 0.0558 0.173
Mycobacterium tuberculosis Probable lipase LipD 0.0114 0.0558 0.1206
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.003 0.0064 0.0869
Brugia malayi RNA recognition motif domain containing protein 0.0336 0.1864 0.185
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.006 0.0086
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0055 0.0106
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0473 0.267 1
Mycobacterium tuberculosis Probable reductase 0.0195 0.1038 0.2374
Echinococcus multilocularis dna polymerase eta 0.0081 0.0363 0.0377
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.0183 0.0355
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0052 0.0196 0.0487
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0063 0.0007
Loa Loa (eye worm) hypothetical protein 0.0145 0.0744 0.0738
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0063 0.0097
Onchocerca volvulus Glucosylceramidase homolog 0.0523 0.2967 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0216 0.064
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.072 0.1402
Mycobacterium ulcerans esterase/lipase LipP 0.0114 0.0558 0.186
Leishmania major guanosine monophosphate reductase 0.0502 0.2846 1
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0502 0.2846 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0195 0.1038 0.2374
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.2967 0.6431
Trypanosoma cruzi DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Echinococcus multilocularis geminin 0.0892 0.5136 0.5334
Brugia malayi MH2 domain containing protein 0.0052 0.0196 0.018
Trypanosoma cruzi chloride channel protein, putative 0.003 0.0064 0.0101
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.003 0.0064 0.0067
Echinococcus multilocularis mothers against decapentaplegic 5 0.0117 0.0577 0.06
Trypanosoma cruzi DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1655 0.9628 1
Chlamydia trachomatis CBS domain-containing protein 0.003 0.0064 1
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0523 1
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.003 0.0064 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.2967 0.6431
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0342 0.0355
Loa Loa (eye worm) MH1 domain-containing protein 0.0117 0.0577 0.0572
Loa Loa (eye worm) hypothetical protein 0.0114 0.0558 0.0553
Toxoplasma gondii thioredoxin reductase 0.0086 0.0392 0.1269
Loa Loa (eye worm) chloride channel 3 0.003 0.0064 0.0058
Echinococcus granulosus mothers against decapentaplegic 5 0.0117 0.0577 0.1124
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0523 0.1121
Brugia malayi jmjC domain containing protein 0.0036 0.01 0.0084
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0797 0.458 0.4571
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0063 0.0104
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0523 1
Echinococcus multilocularis tar DNA binding protein 0.0336 0.1864 0.1936
Onchocerca volvulus 0.0033 0.0085 0.0106
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.016 0.0166
Leishmania major chloride channel protein, putative 0.003 0.0064 0.0101
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0209 0.1117 0.1103
Plasmodium vivax SET domain protein, putative 0.0033 0.0085 0.0189
Brugia malayi beta-lactamase family protein 0.0114 0.0558 0.0542
Brugia malayi CBS domain containing protein 0.003 0.0064 0.0047
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0063 0.0065
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0577 0.0572
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.003 0.0064 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0523 0.1025
Schistosoma mansoni chloride channel protein 0.003 0.0064 0.0125
Loa Loa (eye worm) hypothetical protein 0.0114 0.0558 0.0553
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.01 0.0195
Loa Loa (eye worm) hypothetical protein 0.0081 0.0363 0.0357
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0063 0.0097
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.003 0.0064 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0216 0.064
Loa Loa (eye worm) hypothetical protein 0.0041 0.0131 0.0125
Brugia malayi Pre-SET motif family protein 0.0033 0.0085 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.2967 0.6431
Schistosoma mansoni smad 0.0052 0.0196 0.0382
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0459 0.2592 0.2587
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0145 0.0744 0.0772
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0502 0.2846 0.678
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.2967 0.6431
Echinococcus granulosus dna polymerase kappa 0.0081 0.0363 0.0706
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0081 0.0363 0.0706
Schistosoma mansoni smad 0.0117 0.0577 0.1124
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.003 0.0064 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.0058
Onchocerca volvulus Putative GMP reductase 0.0209 0.1117 0.365
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0063 0.0097
Trichomonas vaginalis glucosylceramidase, putative 0.0797 0.458 1
Brugia malayi Thioredoxin reductase 0.0086 0.0392 0.0376
Brugia malayi MH2 domain containing protein 0.0117 0.0577 0.0562
Treponema pallidum NADH oxidase 0.003 0.0063 0.0066
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0233 0.1261 0.1256
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.072 0.0748
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.012 0.0124
Trichomonas vaginalis glucosylceramidase, putative 0.0797 0.458 1
Brugia malayi MH1 domain containing protein 0.0117 0.0577 0.0562
Schistosoma mansoni protein kinase subunit gamma 0.003 0.0064 0.0125
Echinococcus multilocularis mothers against decapentaplegic 6 0.0052 0.0196 0.0204
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0114 0.0558 0.1087
Treponema pallidum Mg2+ transport protein (mgtE) 0.003 0.0064 0.0089
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.003 0.0064 0.0067
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.003 0.0064 0.0101
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.006 0.0092
Leishmania major hypothetical protein, conserved 0.003 0.0064 0.0101
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.0058
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0523 0.1019
Mycobacterium ulcerans beta-lactamase 0.0114 0.0558 0.186
Trypanosoma brucei DNA polymerase IV, putative 0.0081 0.0363 0.1164
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0063 0.0097
Mycobacterium tuberculosis Probable lipase LipE 0.0114 0.0558 0.1206
Toxoplasma gondii CBS domain-containing protein 0.003 0.0064 0.0101
Mycobacterium tuberculosis Conserved protein 0.003 0.0064 0.0003
Brugia malayi CLC chloride channel protein 0.003 0.0064 0.0047
Brugia malayi beta-lactamase 0.0114 0.0558 0.0542
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.072 0.0748
Echinococcus granulosus mothers against decapentaplegic 2 0.0052 0.0196 0.0382
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0342 0.0666
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0558 0.1102
Loa Loa (eye worm) hypothetical protein 0.0114 0.0558 0.0553
Trypanosoma cruzi DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.003 0.0064 0.0869
Echinococcus granulosus peregrin 0.0031 0.0068 0.0132
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0523 0.1735
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0055 0.0049
Plasmodium falciparum protein MAM3, putative 0.003 0.0064 0.0108
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0198 0.0385
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Trypanosoma brucei DNA polymerase eta, putative 0.0081 0.0363 0.1164
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0523 0.1019
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0523 0.1025
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.0058
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.003 0.0064 0.0003
Trypanosoma brucei unspecified product 0.0056 0.0216 0.064
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0473 0.267 0.9375
Brugia malayi ImpB/MucB/SamB family protein 0.0081 0.0363 0.0347
Brugia malayi MH1 domain containing protein 0.0065 0.0269 0.0253
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.003 0.0064 0.0003
Schistosoma mansoni terminal deoxycytidyl transferase 0.0081 0.0363 0.0706
Echinococcus multilocularis smad 0.0117 0.0577 0.06
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0502 0.2846 0.5541
Echinococcus multilocularis mothers against decapentaplegic 2 0.0052 0.0196 0.0204
Plasmodium falciparum thioredoxin reductase 0.003 0.0063 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0216 0.064
Echinococcus multilocularis GPCR, family 2 0.0145 0.0744 0.0772
Schistosoma mansoni hypothetical protein 0.0145 0.0744 0.1448
Loa Loa (eye worm) hypothetical protein 0.0314 0.1736 0.1731
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.003 0.0064 0.0101
Leishmania major chloride channel protein, putative 0.003 0.0064 0.0101
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0523 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0145 0.0744 0.1448
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.016 0.0363
Loa Loa (eye worm) hypothetical protein 0.0048 0.0173 0.0167
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0063 0.0097
Mycobacterium tuberculosis Conserved protein 0.003 0.0064 0.0003
Trichomonas vaginalis esterase, putative 0.0114 0.0558 0.1102
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.016 0.0154
Echinococcus granulosus jumonji domain containing protein 0.0039 0.012 0.0233
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0063 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0085 0.0166
Echinococcus granulosus geminin 0.0892 0.5136 1
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.003 0.0064 0.0004
Trypanosoma cruzi GMP reductase 0.0502 0.2846 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0063 0.0123
Schistosoma mansoni DNA polymerase eta 0.0081 0.0363 0.0706
Echinococcus granulosus mothers against decapentaplegic 6 0.0052 0.0196 0.0382
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0017 0.0018
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0055 0.0067
Loa Loa (eye worm) Smad1 0.0117 0.0577 0.0572
Schistosoma mansoni smad1 5 8 and 0.0117 0.0577 0.1124
Entamoeba histolytica hypothetical protein 0.0077 0.0342 0.6084
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.0432 0.0449
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0558 0.1102
Giardia lamblia PHD finger protein 15 0.0028 0.0055 0.0577
Trypanosoma cruzi chloride channel protein, putative 0.003 0.0064 0.0101
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0502 0.2846 1
Echinococcus multilocularis peregrin 0.0031 0.0068 0.0071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.072 0.1402
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0523 0.1651
Trypanosoma brucei DNA polymerase IV, putative 0.0081 0.0363 0.1164
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.003 0.0064 0.0101
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0145 0.0744 0.0728
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.003 0.0064 0.0125
Schistosoma mansoni tar DNA-binding protein 0.0336 0.1864 0.3629
Echinococcus granulosus H:Cl exchange transporter 4 0.003 0.0064 0.0125
Brugia malayi PHD-finger family protein 0.0024 0.003 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0797 0.458 1
Toxoplasma gondii IMP dehydrogenas 0.0502 0.2846 1
Plasmodium falciparum phd finger protein, putative 0.0028 0.0055 0.0072
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0354 0.1969 0.6575
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0063 0.0097
Brugia malayi beta-lactamase family protein 0.0114 0.0558 0.0542
Mycobacterium tuberculosis Conserved protein 0.0114 0.0558 0.1206
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.016 0.0312
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0195 0.1038 0.2374
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.006 0.0743
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.009 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.003 0.0064 0.0125
Echinococcus granulosus thioredoxin glutathione reductase 0.0086 0.0395 0.0769
Plasmodium falciparum thioredoxin reductase 0.0086 0.0392 0.1353
Brugia malayi phosphofructokinase 0.0108 0.0523 0.0507
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0195 0.1038 0.35
Echinococcus granulosus beta LACTamase domain containing family member 0.0114 0.0558 0.1087
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0502 0.2846 0.2956
Loa Loa (eye worm) hypothetical protein 0.0354 0.1969 0.1965
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0502 0.2846 1
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0502 0.2846 0.5541
Schistosoma mansoni hypothetical protein 0.0281 0.154 0.2999
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0182 0.0959 0.1868
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0264 0.1441 0.3358
Brugia malayi Latrophilin receptor protein 2 0.0145 0.0744 0.0728
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0523 0.1735
Mycobacterium ulcerans DNA polymerase IV 0.0081 0.0363 0.1164
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0336 0.1864 0.1859
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.0432 0.0842
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0085 0.0166
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.003 0.0064 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.072 0.1402
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0063 0.0097
Loa Loa (eye worm) hypothetical protein 0.0068 0.0291 0.0286
Brugia malayi MH2 domain containing protein 0.0117 0.0577 0.0562
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0063 0.0097
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0239 0.1293 0.4418
Brugia malayi glutathione reductase 0.0086 0.0392 0.0376
Trypanosoma brucei unspecified product 0.0081 0.0363 0.1164
Loa Loa (eye worm) latrophilin receptor protein 2 0.0145 0.0744 0.0738
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0093 0.0097
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0231 0.0226
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Schistosoma mansoni DNA polymerase IV / kappa 0.0025 0.0036 0.0069
Schistosoma mansoni tar DNA-binding protein 0.0336 0.1864 0.3629
Brugia malayi Bromodomain containing protein 0.0037 0.0107 0.009
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0502 0.2846 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0114 0.0558 0.1206
Trypanosoma cruzi DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0198 0.0205
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0063 0.0123
Brugia malayi jmjC domain containing protein 0.0092 0.0432 0.0416
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.01 0.0195
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0081 0.0363 0.0377
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.016 0.0312
Brugia malayi 6-phosphofructokinase 0.0108 0.0523 0.0507
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0063 0.0104
Loa Loa (eye worm) MBCTL1 0.0053 0.0198 0.0192
Loa Loa (eye worm) IMP dehydrogenase 1 0.0502 0.2846 0.2842
Echinococcus multilocularis thioredoxin glutathione reductase 0.0086 0.0395 0.041
Brugia malayi ancient conserved domain protein 4 0.003 0.0064 0.0047
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0063 0.0097
Echinococcus granulosus tar DNA binding protein 0.0336 0.1864 0.3629
Mycobacterium tuberculosis Probable oxidoreductase 0.0217 0.1166 0.2687
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.2967 0.6431
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0523 0.1735
Mycobacterium tuberculosis Conserved protein 0.0114 0.0558 0.1206
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0114 0.0558 0.0553
Brugia malayi MH1 domain containing protein 0.0117 0.0577 0.0562
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0063 0.0097
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0063 0.0046
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0055 0.0106
Mycobacterium ulcerans hypothetical protein 0.003 0.0064 0.0101
Wolbachia endosymbiont of Brugia malayi hemolysin 0.003 0.0064 0.0004
Toxoplasma gondii ABC1 family protein 0.0114 0.0558 0.186
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.0558 0.186
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0081 0.0363 0.0357
Echinococcus granulosus dna polymerase eta 0.0081 0.0363 0.0706
Entamoeba histolytica hypothetical protein 0.0077 0.0342 0.6084
Mycobacterium ulcerans hypothetical protein 0.003 0.0064 0.0101
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.003 0.0064 0.0101
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.003 0.0064 0.0067
Echinococcus granulosus Smad4 0.0117 0.0577 0.1124
Trichomonas vaginalis penicillin-binding protein, putative 0.0114 0.0558 0.1102
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0055 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Brugia malayi Smad1 0.0117 0.0577 0.0562
Echinococcus granulosus H:Cl exchange transporter 3 0.003 0.0064 0.0125
Loa Loa (eye worm) hypothetical protein 0.0046 0.016 0.0154
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.016 0.0312
Mycobacterium ulcerans transcriptional regulator 0.003 0.0064 0.0101
Loa Loa (eye worm) MH2 domain-containing protein 0.1718 1 1
Brugia malayi MH1 domain containing protein 0.0065 0.0269 0.0253
Brugia malayi polk-prov protein 0.0025 0.0036 0.0019
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0217 0.1166 0.3961
Loa Loa (eye worm) transcription factor SMAD2 0.1718 1 1
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0264 0.1441 0.4951
Plasmodium falciparum glutathione reductase 0.0086 0.0392 0.1353
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0114 0.0558 0.1206
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0063 0.0104
Trypanosoma brucei hypothetical protein, conserved 0.0114 0.0558 0.186
Trypanosoma cruzi chloride channel protein, putative 0.003 0.0064 0.0101
Entamoeba histolytica deoxycytidyl transferase, putative 0.0081 0.0363 0.6536
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0145 0.0744 0.1448
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.0058
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.006 0.0092
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0523 0.1025
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0363 0.1164
Brugia malayi mbt repeat family protein 0.0046 0.016 0.0144
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0195 0.1038 0.2374
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0081 0.0363 0.1164
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.0558 0.186
Brugia malayi TAR-binding protein 0.0336 0.1864 0.185
Plasmodium falciparum glutathione reductase 0.003 0.0063 0.0104
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0473 0.267 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0217 0.1166 0.2687
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.003 0.0064 0.0003
Echinococcus multilocularis dna polymerase kappa 0.0081 0.0363 0.0377
Toxoplasma gondii CBS family protein 0.003 0.0064 0.0101
Trichomonas vaginalis glucosylceramidase, putative 0.0797 0.458 1
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0012
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0342 0.0666
Leishmania major inosine-5-monophosphate dehydrogenase 0.0502 0.2846 1
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0502 0.2846 0.2834
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0523 0.1735
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.006 0.0092
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0063 0.0097
Echinococcus multilocularis Smad4 0.0117 0.0577 0.06
Schistosoma mansoni tar DNA-binding protein 0.0336 0.1864 0.3629
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0727 0.4168 1
Mycobacterium leprae Probable lipase LipE 0.0114 0.0558 0.1777
Mycobacterium ulcerans DNA polymerase IV 0.0081 0.0363 0.1164
Plasmodium vivax hypothetical protein, conserved 0.0114 0.0558 0.1984
Brugia malayi Bromodomain containing protein 0.0073 0.0316 0.03
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0017 0.0033
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.072 0.0704
Mycobacterium ulcerans hypothetical protein 0.003 0.0064 0.0101
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0523 0.0518
Trichomonas vaginalis set domain proteins, putative 0.0265 0.1451 0.3077
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0063 0.7469
Loa Loa (eye worm) nuclear factor I 0.0065 0.0269 0.0264
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0017 0.0033
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0063 0.0104
Schistosoma mansoni hypothetical protein 0.0077 0.0342 0.0666
Echinococcus granulosus smad 0.0117 0.0577 0.1124
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0055 0.0057
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.003 0.0064 0.0869
Echinococcus granulosus GPCR family 2 0.0145 0.0744 0.1448
Trypanosoma cruzi chloride channel protein, putative 0.003 0.0064 0.0101
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0081 0.0363 0.067
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0229 0.0237
Onchocerca volvulus 0.0114 0.0558 0.173
Brugia malayi Voltage gated chloride channel family protein 0.003 0.0064 0.0047
Schistosoma mansoni Smad4 0.0052 0.0196 0.0382
Schistosoma mansoni hypothetical protein 0.0145 0.0744 0.1448
Trypanosoma brucei trypanothione reductase 0.0086 0.0392 0.1269
Schistosoma mansoni hypothetical protein 0.0314 0.1736 0.3381
Leishmania major trypanothione reductase 0.0086 0.0392 0.1269
Treponema pallidum hemolysin (tlyC) 0.003 0.0064 0.0089
Entamoeba histolytica hypothetical protein 0.0077 0.0342 0.6084
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.2967 0.6431
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0523 0.1025
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0217 0.1166 0.2687
Mycobacterium tuberculosis Probable dehydrogenase 0.0195 0.1038 0.2374
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0797 0.458 0.4577
Echinococcus multilocularis beta LACTamase domain containing family member 0.0114 0.0558 0.058
Loa Loa (eye worm) hypothetical protein 0.0459 0.2592 0.2587
Brugia malayi ImpB/MucB/SamB family protein 0.0081 0.0363 0.0347
Loa Loa (eye worm) beta-lactamase 0.0114 0.0558 0.0553
Schistosoma mansoni hypothetical protein 0.0145 0.0744 0.1448
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0063 0.0097
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0239 0.1293 0.4475
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.003 0.0064 0.0125
Loa Loa (eye worm) MH1 domain-containing protein 0.0052 0.0196 0.0191
Loa Loa (eye worm) loechrig isoform VII 0.003 0.0064 0.0058
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0093 0.0181
Schistosoma mansoni hypothetical protein 0.0892 0.5136 1
Schistosoma mansoni jumonji domain containing protein 0.0073 0.0321 0.0624
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.003 0.0064 0.0125
Brugia malayi mothers against decapentaplegic homolog 3 0.0052 0.0196 0.018
Brugia malayi N-terminal motif family protein 0.0354 0.1969 0.1956
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0183 0.0355
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0195 0.1038 0.2374
Schistosoma mansoni chloride channel protein 0.003 0.0064 0.0125
Brugia malayi mbt repeat family protein 0.0046 0.016 0.0144
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0523 0.0518
Leishmania major CBS domain protein, conserved 0.003 0.0064 0.0101
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0114 0.0558 0.0542
Trypanosoma cruzi GMP reductase 0.0502 0.2846 1
Mycobacterium ulcerans hypothetical protein 0.0114 0.0558 0.186
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0063 0.0097
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0063 0.0837
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0459 0.2592 0.2579
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0081 0.0363 0.073
Onchocerca volvulus 0.0265 0.1451 0.4794
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0063 0.0097
Brugia malayi Pre-SET motif family protein 0.0233 0.1261 0.1246
Loa Loa (eye worm) thioredoxin reductase 0.0086 0.0392 0.0386
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0063 0.0097
Loa Loa (eye worm) hypothetical protein 0.0114 0.0558 0.0553
Trichomonas vaginalis glucosylceramidase, putative 0.0551 0.3133 0.6798
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0523 0.0543
Loa Loa (eye worm) RNA binding protein 0.0336 0.1864 0.1859
Trypanosoma brucei unspecified product 0.0056 0.0216 0.064
Trichomonas vaginalis DNA polymerase eta, putative 0.0081 0.0363 0.067
Trypanosoma cruzi DNA polymerase eta, putative 0.0081 0.0363 0.1164
Schistosoma mansoni Smad4 0.0117 0.0577 0.1124
Brugia malayi Bromodomain containing protein 0.0031 0.0068 0.0051
Schistosoma mansoni hypothetical protein 0.0028 0.0055 0.0106
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0063 0.0097
Trypanosoma brucei DNA polymerase IV, putative 0.0081 0.0363 0.1164
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0114 0.0558 0.186
Onchocerca volvulus 0.0114 0.0558 0.173
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.0183 0.0355
Loa Loa (eye worm) hypothetical protein 0.0114 0.0558 0.0553
Trichomonas vaginalis glucosylceramidase, putative 0.0797 0.458 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0055 0.0049
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0086 0.0392 0.0802
Schistosoma mansoni tar DNA-binding protein 0.0336 0.1864 0.3629
Giardia lamblia DINP protein human, muc B family 0.0081 0.0363 1
Onchocerca volvulus 0.0046 0.016 0.0363
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.0183 0.019
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0198 0.0385
Brugia malayi hypothetical protein 0.0077 0.0342 0.0326
Trichomonas vaginalis penicillin-binding protein, putative 0.0114 0.0558 0.1102
Trichomonas vaginalis glucosylceramidase, putative 0.0797 0.458 1
Schistosoma mansoni smad1 5 8 and 0.0117 0.0577 0.1124
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.003 0.0064 0.0003
Schistosoma mansoni hypothetical protein 0.0145 0.0744 0.1448
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0198 0.0181
Mycobacterium tuberculosis Probable esterase LipL 0.0114 0.0558 0.1206
Plasmodium vivax glutathione reductase, putative 0.0086 0.0392 0.1353
Schistosoma mansoni hypothetical protein 0.0892 0.5136 1
Loa Loa (eye worm) hypothetical protein 0.0114 0.0558 0.0553
Schistosoma mansoni tar DNA-binding protein 0.0336 0.1864 0.3629
Echinococcus granulosus TGF beta signal transducer SmadC 0.0117 0.0577 0.1124
Trichomonas vaginalis glucosylceramidase, putative 0.0523 0.2967 0.6431
Schistosoma mansoni smad1 5 8 and 0.0117 0.0577 0.1124
Mycobacterium tuberculosis Conserved hypothetical protein 0.0081 0.0363 0.073
Loa Loa (eye worm) TAR-binding protein 0.0336 0.1864 0.1859
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0063 0.0097
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.072 0.1402
Schistosoma mansoni bromodomain containing protein 0.0061 0.0249 0.0485
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.016 0.0166
Plasmodium vivax thioredoxin reductase, putative 0.0086 0.0392 0.1353

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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