Detailed information for compound 957082

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 413.833 | Formula: C16H16ClN3O6S
  • H donors: 1 H acceptors: 5 LogP: 2.61 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClC1CCN(CC1)S(=O)(=O)c1ccc(cc1)NC(=O)c1ccc(o1)[N+](=O)[O-]
  • InChi: 1S/C16H16ClN3O6S/c17-11-7-9-19(10-8-11)27(24,25)13-3-1-12(2-4-13)18-16(21)14-5-6-15(26-14)20(22)23/h1-6,11H,7-10H2,(H,18,21)
  • InChiKey: XKMLYHZJKCRLOI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens DNA-damage-inducible transcript 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Toxoplasma gondii hypothetical protein DNA-damage-inducible transcript 3 192 aa 159 aa 23.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0019 0.0123 0.0247
Echinococcus granulosus importin subunit beta 1 0.0028 0.0236 0.0474
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0281 0.4758
Echinococcus granulosus neuropeptide FF receptor 2 0.0014 0.0055 0.011
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0053 0.0558 0.0644
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0143 0.0177
Echinococcus granulosus General substrate transporter 0.0087 0.0998 0.2003
Loa Loa (eye worm) GABA receptor subunit 0.0065 0.0717 0.0826
Loa Loa (eye worm) hypothetical protein 0.009 0.1032 0.119
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0081 0.0966
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0516 0.1035
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.006 0.0069
Onchocerca volvulus 0.0026 0.0213 0.0626
Brugia malayi Sugar transporter family protein 0.0014 0.006 0.0069
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.003 0.0035
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.1374 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0558 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0021
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0201 0.3241
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0075 0.015
Schistosoma mansoni biogenic amine receptor 0.0014 0.0055 0.011
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0338 0.4586
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Onchocerca volvulus 0.0014 0.0055 0.0161
Echinococcus granulosus snurportin 1 0.0299 0.3714 0.7453
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0062 0.0125
Echinococcus granulosus nAChR subunit 0.0065 0.0717 0.1438
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0056 0.0113
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0122 0.1436 0.2881
Brugia malayi Cation transporter family protein 0.0122 0.1436 0.1656
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0143 0.0177
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0014 0.0055 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0143 0.1782
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0213 0.1704
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0014 0.0055 0.011
Brugia malayi G protein-coupled receptor F59B2.13 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Schistosoma mansoni glucose transport protein 0.0102 0.1181 0.2371
Brugia malayi hypothetical protein 0.023 0.2829 0.3262
Onchocerca volvulus 0.0014 0.0055 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0257 0.0516
Echinococcus granulosus allatostatin A receptor 0.0014 0.0055 0.011
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0065 0.0717 0.1438
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0098 0.0112
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0122 0.1436 0.1656
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0438 0.0879
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0014 0.0055 0.011
Schistosoma mansoni neurotransmitter gated ion channel 0.0056 0.0596 0.1196
Echinococcus multilocularis G protein coupled receptor 139 0.0014 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0294 0.0409
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Onchocerca volvulus 0.0014 0.0055 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0098 0.0113
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.006 0.0069
Schistosoma mansoni integrin alpha-ps 0.0028 0.0233 0.0468
Echinococcus multilocularis solute carrier family 22 0.0014 0.006 0.006
Onchocerca volvulus 0.0014 0.006 0.0177
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1181 0.1181
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0014 0.0055 0.0063
Leishmania major GTP-binding protein, putative 0.0021 0.0141 0.2103
Brugia malayi Cation transporter family protein 0.0122 0.1436 0.1656
Giardia lamblia Hexose transporter 0.0014 0.006 0.1002
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0365 0.8254
Onchocerca volvulus 0.0014 0.006 0.0177
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0447 0.0897
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0011 0.0018 0.0018
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0338 0.5838
Onchocerca volvulus 0.0122 0.1436 0.4213
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0098 0.0196
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0143 0.0177
Brugia malayi bHLH-PAS transcription factor 0.0151 0.1817 0.2095
Schistosoma mansoni amine GPCR 0.0014 0.0055 0.011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0447 0.0897
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Brugia malayi RE15519p 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0033 0.0305 0.0352
Echinococcus granulosus G protein coupled receptor 139 0.0014 0.0055 0.011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0055 0.0055
Echinococcus granulosus lamin 0.0026 0.0213 0.0428
Leishmania major protein kinase, putative 0.0053 0.0558 1
Schistosoma mansoni hypothetical protein 0.005 0.0522 0.1048
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Onchocerca volvulus 0.0014 0.006 0.0177
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.1686 0.1686
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1181 0.1181
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0065 0.013
Echinococcus multilocularis solute carrier family 22 0.0014 0.006 0.006
Mycobacterium leprae Possible regulatory protein 0.0053 0.0558 0.2975
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0014 0.0055 0.0055
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0122 0.1436 0.1656
Echinococcus multilocularis G-protein coupled receptor, putative 0.0014 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0686 0.8671 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0281 0.039
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Echinococcus granulosus g protein coupled receptor 0.0014 0.0055 0.011
Brugia malayi CXXC zinc finger family protein 0.0028 0.0235 0.0271
Echinococcus multilocularis ATP binding cassette sub family B 0.002 0.014 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0065 0.0058
Trypanosoma brucei sugar transporter, putative 0.0014 0.006 0.0684
Onchocerca volvulus Putative transporter 0.0014 0.006 0.0177
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0503 0.058
Brugia malayi Thioredoxin reductase 0.0046 0.0467 0.0539
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.2829 0.2829
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0081 0.0081
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.1223 0.8856
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0141 0.0163
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0039 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.1436 0.1656
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0112
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0143 0.0628
Echinococcus multilocularis jun protein 0.035 0.4373 0.4373
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Onchocerca volvulus 0.0065 0.0717 0.2103
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Brugia malayi photoreceptor-specific nuclear receptor 0.0017 0.0098 0.0113
Trypanosoma cruzi hexose transporter 0.0032 0.0281 0.4758
Echinococcus multilocularis protocadherin 11 0.0011 0.0018 0.0018
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0143 0.0177
Brugia malayi Pre-SET motif family protein 0.0203 0.2483 0.2863
Brugia malayi Cell death specification protein 2 0.0011 0.0018 0.0021
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0191 0.117
Echinococcus granulosus glycine receptor subunit alpha 1 0.0122 0.1436 0.2881
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0081 0.0966
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0122 0.1436 0.1656
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0852 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Schistosoma mansoni acetylcholine receptor-related 0.0056 0.0596 0.1196
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0098 0.0098
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0081 0.0285
Loa Loa (eye worm) hypothetical protein 0.0012 0.0033 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0179 0.0233
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Onchocerca volvulus 0.0019 0.0123 0.0361
Schistosoma mansoni hypothetical protein 0.0047 0.0479 0.0961
Brugia malayi nuclear receptor NHR-88 0.0017 0.0098 0.0113
Echinococcus multilocularis geminin 0.033 0.4104 0.4104
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0112
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0852 0.4597
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0143 0.0177
Onchocerca volvulus 0.0011 0.0018 0.0053
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0056 0.0056
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0323 0.5555
Brugia malayi putative neuropeptide receptor 0.0014 0.0055 0.0063
Trichomonas vaginalis guanylate cyclase, putative 0.0053 0.0558 0.0814
Onchocerca volvulus Bile acid receptor homolog 0.0017 0.0098 0.0286
Schistosoma mansoni integrin alpha-ps 0.0053 0.0561 0.1127
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0036
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0281 0.039
Leishmania major protein kinase, putative 0.0053 0.0558 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0323 0.0453
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0143 0.0177
Trypanosoma cruzi sugar transporter, putative 0.0014 0.006 0.0566
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0122 0.1436 0.1436
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0438 0.933
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.006 0.005
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0055 0.011
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0467 0.3629
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0236 0.0236
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0055 0.0055
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0081 0.0094
Echinococcus granulosus death domain containing protein 0.0014 0.0056 0.0113
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0055 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.006 0.005
Echinococcus granulosus solute carrier family 22 0.0014 0.006 0.0121
Brugia malayi Cell death specification protein 2 0.0011 0.0018 0.0021
Echinococcus granulosus glycine receptor subunit beta 0.0122 0.1436 0.2881
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0098 0.0098
Loa Loa (eye worm) sugar transporter 0.0102 0.1181 0.1362
Brugia malayi glutathione reductase 0.0046 0.0467 0.0539
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0143 0.0286
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0014 0.0055 0.0055
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0098 0.0112
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Leishmania major glucose transporter, lmgt1 0.0032 0.0281 0.4758
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0447 0.0897
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0467 0.3098
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0065 0.0655
Schistosoma mansoni thyrotroph embryonic factor related 0.0011 0.0018 0.0036
Echinococcus multilocularis aryl hydrocarbon receptor 0.0053 0.0558 0.0558
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0141 0.0723
Onchocerca volvulus 0.0019 0.0123 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0323 0.0453
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Schistosoma mansoni neuropeptide receptor 0.0014 0.0055 0.011
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0438 0.7721
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus granulosus cpg binding protein 0.003 0.0256 0.0513
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0558 0.0814
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0122 0.1436 0.1436
Echinococcus granulosus neuropeptides capa receptor 0.0014 0.0055 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0055 0.011
Trichomonas vaginalis glucose transporter, putative 0.0014 0.006 0.005
Echinococcus granulosus transcriptional factor nfil3:e4bp4 0.0011 0.0018 0.0036
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0503 0.058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Schistosoma mansoni coup transcription factor 0.0017 0.0098 0.0196
Echinococcus granulosus survival motor neuron protein 1 0.023 0.2829 0.5677
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0122 0.1436 0.1656
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0503 0.058
Entamoeba histolytica hypothetical protein 0.0035 0.0326 0.4406
Plasmodium falciparum thioredoxin reductase 0.0046 0.0467 0.3629
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0065 0.0065
Onchocerca volvulus 0.0047 0.0479 0.1405
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0143 0.0286
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0558 0.0814
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.0596 0.0687
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0438 0.0505
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Brugia malayi Cytochrome P450 family protein 0.0012 0.003 0.0035
Trichomonas vaginalis abcb9, putative 0.0021 0.0143 0.0177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0438 0.0438
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0143 0.0177
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0027 0.0031
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0122 0.1436 0.1656
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0191 0.3053
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0123 0.0247
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0098 0.0098
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0257 0.1757
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0122 0.1436 0.1436
Brugia malayi Melatonin receptor type 1A 0.0014 0.0055 0.0063
Toxoplasma gondii thioredoxin reductase 0.0046 0.0467 0.3629
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0257 0.0516
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0338 0.0679
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0055 0.0055
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0257 0.0516
Brugia malayi hypothetical protein 0.0056 0.0596 0.0687
Trichomonas vaginalis taga, putative 0.0021 0.0143 0.0177
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0056 0.0596 0.0687
Onchocerca volvulus 0.0021 0.0143 0.0418
Echinococcus granulosus neuropeptides capa receptor 0.0014 0.0055 0.011
Schistosoma mansoni hypothetical protein 0.0014 0.0055 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.018 0.0234
Loa Loa (eye worm) hypothetical protein 0.0014 0.0058 0.0067
Schistosoma mansoni nAChR subunit 0.0056 0.0596 0.1196
Loa Loa (eye worm) neuropeptide F receptor 0.0014 0.0055 0.0063
Onchocerca volvulus 0.0014 0.0055 0.0161
Onchocerca volvulus 0.0014 0.0055 0.0161
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0065 0.0655
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0209 0.0278
Plasmodium falciparum glutathione reductase 0.0016 0.0081 0.0188
Schistosoma mansoni hypothetical protein 0.033 0.4104 0.8237
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.006 0.0069
Onchocerca volvulus 0.0014 0.006 0.0177
Onchocerca volvulus 0.0011 0.0018 0.0053
Trypanosoma brucei glucose transporter, putative 0.0032 0.0281 0.5749
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0123 0.0123
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0081 0.0161
Schistosoma mansoni neuropeptide F-like receptor 0.0014 0.0055 0.011
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0056 0.0596 0.0596
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.1436 0.1656
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0338 0.0679
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0143 0.0177
Schistosoma mansoni sugar transporter 0.0014 0.006 0.0121
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0141 0.0163
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0143 0.0735
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus granulosus lamin dm0 0.0026 0.0213 0.0428
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0098 0.0098
Schistosoma mansoni single-minded 0.0204 0.2498 0.5013
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0338 0.0338
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0122 0.1436 0.2881
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Onchocerca volvulus 0.0275 0.3408 1
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0852 0.0852
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0098 0.0196
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Echinococcus multilocularis fmrfamide receptor 0.0014 0.0055 0.0055
Onchocerca volvulus 0.0122 0.1436 0.4213
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Plasmodium falciparum hexose transporter 0.0102 0.1181 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0014 0.0055 0.0161
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.006 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0294 0.0409
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0081 0.0188
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0122 0.1436 0.2881
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0056 0.0596 0.0596
Trichomonas vaginalis adenylate cyclase, putative 0.0053 0.0558 0.0814
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0081 0.0966
Echinococcus multilocularis General substrate transporter 0.0087 0.0998 0.0998
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Onchocerca volvulus Huntingtin homolog 0.0119 0.1406 0.4127
Onchocerca volvulus 0.0056 0.0596 0.1749
Echinococcus multilocularis orexin receptor type 2 0.0014 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Schistosoma mansoni cpg binding protein 0.0028 0.0235 0.0472
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0294 0.0409
Schistosoma mansoni opsin-like receptor 0.0014 0.0055 0.011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0447 0.0897
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0323 0.5555
Trypanosoma cruzi hexose transporter, putative 0.0014 0.006 0.0566
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0081 0.0188
Brugia malayi Serotonin receptor 0.0014 0.0055 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0055 0.0055
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0852 0.1709
Echinococcus granulosus intermediate filament protein 0.0026 0.0213 0.0428
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0143 0.0177
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0014 0.0055 0.0063
Schistosoma mansoni hypothetical protein 0.0398 0.4983 1
Brugia malayi nuclear hormone receptor 0.0017 0.0098 0.0113
Trypanosoma brucei glucose transporter 2A 0.0032 0.0281 0.5749
Brugia malayi intermediate filament protein 0.0026 0.0213 0.0246
Schistosoma mansoni integrin alpha 0.0053 0.0561 0.1127
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0056 0.0113
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0143 0.0286
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0409 0.0585
Echinococcus multilocularis neuropeptide receptor A26 0.0014 0.0055 0.0055
Echinococcus multilocularis multidrug resistance protein 1 0.0014 0.0062 0.0062
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0143 0.0164
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0447 0.0515
Schistosoma mansoni alpha-1 adrenergic receptor 0.0014 0.0055 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0179 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0143 0.0164
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0014 0.0055 0.011
Loa Loa (eye worm) sugar transporter 0.0014 0.006 0.0069
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0281 0.5749
Schistosoma mansoni lipoxygenase 0.0115 0.1349 0.2707
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0141 0.0723
Echinococcus granulosus neuropeptide receptor 0.0014 0.0055 0.011
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0852 0.7058
Brugia malayi Integrin alpha pat-2 precursor 0.0053 0.0561 0.0647
Echinococcus granulosus 7tm_1 domain containing protein 0.0014 0.0055 0.011
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0055 0.011
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0081 0.0966
Brugia malayi Probable ClpP-like protease 0.0076 0.0852 0.0982
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1181 0.1181
Brugia malayi major facilitator superfamily protein 0.0014 0.006 0.0069
Echinococcus multilocularis RUN 0.0019 0.0123 0.0123
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0852 1
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0852 0.7058
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0098 0.0196
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0081 0.0163
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0055 0.0055
Schistosoma mansoni polycystin 1-related 0.0019 0.0123 0.0247
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0122 0.1436 0.2881
Loa Loa (eye worm) hypothetical protein 0.0049 0.0503 0.058
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0014 0.0055 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0122 0.1436 0.1656
Brugia malayi Flap endonuclease-1 0.0025 0.0201 0.0232
Entamoeba histolytica hypothetical protein 0.0023 0.0168 0.2148
Schistosoma mansoni neuropeptide receptor 0.0014 0.0055 0.011
Onchocerca volvulus 0.0026 0.0213 0.0626
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0021
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0014 0.0055 0.0063
Onchocerca volvulus Putative nachr subunit 0.0122 0.1436 0.4213
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.006 0.005
Echinococcus multilocularis neuropeptides capa receptor 0.0014 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0294 0.0409
Onchocerca volvulus Neuropeptide F receptor homolog 0.0014 0.0055 0.0161
Brugia malayi G-protein coupled receptor 0.0014 0.0055 0.0063
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0098 0.0196
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.006 0.0167
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0081 0.0966
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0123 0.0247
Schistosoma mansoni sugar transporter 0.0014 0.006 0.0121
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0281 0.5749
Echinococcus granulosus glycine receptor subunit beta 0.0122 0.1436 0.2881
Brugia malayi hypothetical protein 0.0019 0.0123 0.0142
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0081 0.0966
Loa Loa (eye worm) hypothetical protein 0.0026 0.0207 0.0239
Brugia malayi Sugar transporter family protein 0.0102 0.1181 0.1362
Echinococcus granulosus orexin receptor type 2 0.0014 0.0055 0.011
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0011 0.0018 0.0018
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0168 0.0216
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0081 0.1505
Schistosoma mansoni multidrug resistance protein 0.0021 0.0143 0.0286
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0281 0.039
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.1223 0.8856
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.006 0.005
Echinococcus granulosus solute carrier family 22 0.0014 0.006 0.0121
Brugia malayi G protein-coupled receptor 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0098 0.0112
Schistosoma mansoni amine GPCR 0.0014 0.0055 0.011
Onchocerca volvulus 0.0014 0.0055 0.0161
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus multilocularis integrin alpha ps 0.0053 0.0561 0.0561
Schistosoma mansoni importin beta-1 0.0028 0.0236 0.0474
Echinococcus multilocularis transcriptional factor nfil3:e4bp4 0.0011 0.0018 0.0018
Loa Loa (eye worm) CYP4Cod1 0.0012 0.003 0.0035
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0075 0.0075
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0717 0.0826
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0055 0.011
Brugia malayi hypothetical protein 0.0275 0.3408 0.393
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0123 0.0142
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0438 0.7721
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0081 0.0966
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0122 0.1436 0.1656
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0235 0.0271
Brugia malayi Death domain containing protein 0.0014 0.0056 0.0065
Loa Loa (eye worm) hypothetical protein 0.003 0.0257 0.0297
Echinococcus granulosus neuropeptide Y receptor 0.0014 0.0055 0.011
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0141 0.0141
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0143 0.0177
Plasmodium falciparum thioredoxin reductase 0.0016 0.0081 0.0188
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0143 0.0177
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.006 0.0121
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Schistosoma mansoni hypothetical protein 0.0015 0.0075 0.015
Brugia malayi hypothetical protein 0.0019 0.0123 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0294 0.0409
Onchocerca volvulus 0.0014 0.006 0.0177
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.1223 0.8706
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.1223 0.8856
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0122 0.1436 0.2881
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0201 0.2623
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0058 0.0116
Plasmodium falciparum flap endonuclease 1 0.0025 0.0201 0.1259
Schistosoma mansoni cpg binding protein 0.003 0.0256 0.0513
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0168 0.2613
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.006 0.0121
Schistosoma mansoni multidrug resistance protein 0.0021 0.0143 0.0286
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0338 0.0477
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0516 0.3468
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0338 0.0477
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Echinococcus granulosus tm gpcr rhodopsin 0.0014 0.0055 0.011
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0168 0.0216
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0014 0.0055 0.011
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0281 0.4758
Schistosoma mansoni nAChR subunit 0.0122 0.1436 0.2881
Brugia malayi Uncoordinated protein 44 0.0014 0.0056 0.0065
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0191 0.117
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0142
Onchocerca volvulus 0.0065 0.0717 0.2103
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0201 0.1259
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0055 0.011
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.1223 0.8856
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0057 0.0066
Onchocerca volvulus 0.0122 0.1436 0.4213
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0098 0.0196
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0143 0.1782
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Schistosoma mansoni nAChR subunit 0.0122 0.1436 0.2881
Onchocerca volvulus 0.0014 0.006 0.0177
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0112
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0143 0.0177
Schistosoma mansoni rab6-interacting 0.0019 0.0123 0.0247
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0055 0.011
Trichomonas vaginalis guanylate cyclase, putative 0.0053 0.0558 0.0814
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus multilocularis glycine receptor subunit beta 0.0122 0.1436 0.1436
Brugia malayi AKH receptor 0.0014 0.0055 0.0063
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0056 0.0596 0.0687
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.1374 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0233 0.0269
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0143 0.0796
Schistosoma mansoni opsin-like receptor 0.0014 0.0055 0.011
Brugia malayi hypothetical protein 0.0119 0.1406 0.1622
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Entamoeba histolytica hypothetical protein 0.0035 0.0326 0.4406
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0098 0.0113
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0122 0.1436 0.1656
Brugia malayi follicle stimulating hormone receptor 0.0014 0.0055 0.0063
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0168 0.0216
Brugia malayi Serotonin receptor 0.0465 0.5841 0.6737
Loa Loa (eye worm) hypothetical protein 0.0026 0.0213 0.0246
Leishmania major p-glycoprotein 0.0021 0.0143 0.2128
Brugia malayi Protein kinase domain containing protein 0.0014 0.0056 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0055 0.011
Loa Loa (eye worm) G-protein coupled receptor 0.0014 0.0055 0.0063
Giardia lamblia GTOR 0.0044 0.0438 1
Onchocerca volvulus 0.0011 0.0018 0.0053
Onchocerca volvulus 0.0056 0.0596 0.1749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0065 0.0058
Loa Loa (eye worm) histone methyltransferase 0.001 0.0001 0.0002
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0081 0.0083
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0098 0.0113
Echinococcus granulosus glycine receptor subunit alpha 1 0.0122 0.1436 0.2881
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Echinococcus granulosus single minded 2 0.0151 0.1817 0.3646
Onchocerca volvulus 0.0014 0.006 0.0177
Schistosoma mansoni smdr2 0.0021 0.0143 0.0286
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Schistosoma mansoni neurotransmitter gated ion channel 0.0065 0.0717 0.1438
Loa Loa (eye worm) ACC-1 protein 0.0122 0.1436 0.1656
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0098 0.0113
Onchocerca volvulus 0.0014 0.0055 0.0161
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0081 0.0966
Schistosoma mansoni opsin-like receptor 0.0014 0.0055 0.011
Echinococcus multilocularis glycine receptor subunit beta 0.0122 0.1436 0.1436
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0098 0.0113
Brugia malayi excitatory GABA receptor EXP-1A 0.0122 0.1436 0.1656
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0123 0.0559
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0467 0.0539
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0143 0.0286
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0143 0.0735
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0142 0.2559
Schistosoma mansoni rab6-interacting 0.0019 0.0123 0.0247
Onchocerca volvulus 0.0014 0.006 0.0177
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0294 0.0409
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.1436 0.1656
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Schistosoma mansoni lamin 0.0026 0.0213 0.0428
Echinococcus multilocularis g protein coupled receptor 0.0014 0.0055 0.0055
Brugia malayi hypothetical protein 0.0014 0.006 0.0069
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.1686 0.1945
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0014 0.0062 0.0054
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0053 0.0558 0.0644
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0257 0.0516
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.006 0.005
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0075 0.0086
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0122 0.1436 0.1436
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0143 0.0177
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0014 0.0055 0.011
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus granulosus protocadherin 11 0.0011 0.0018 0.0036
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0014 0.0055 0.0063
Onchocerca volvulus 0.0014 0.006 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.006 0.005
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0011 0.0018 0.0036
Loa Loa (eye worm) G-protein coupled receptor 0.0014 0.0055 0.0063
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0055 0.011
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0081 0.1168
Schistosoma mansoni nAChR subunit 0.0056 0.0596 0.1196
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0112
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0112
Brugia malayi hypothetical protein 0.0035 0.0326 0.0376
Schistosoma mansoni histamine h1 receptor 0.0014 0.0055 0.011
Onchocerca volvulus 0.0122 0.1436 0.4213
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Brugia malayi hypothetical protein 0.0056 0.0596 0.0687
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0081 0.0188
Echinococcus multilocularis cpg binding protein 0.003 0.0256 0.0256
Brugia malayi bZIP transcription factor family protein 0.0011 0.0018 0.0021
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.1436 0.1656
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0098 0.0112
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0852 0.5504
Schistosoma mansoni flap endonuclease-1 0.0023 0.017 0.0342
Brugia malayi Cation transporter family protein 0.0122 0.1436 0.1656
Echinococcus multilocularis musashi 0.0026 0.0213 0.0213
Brugia malayi Dopamine receptor protein 1 0.0014 0.0055 0.0063
Onchocerca volvulus 0.0231 0.2843 0.8344
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus granulosus protocadherin 11 0.0011 0.0018 0.0036
Brugia malayi hypothetical protein 0.0014 0.006 0.0069
Brugia malayi Pre-SET motif family protein 0.003 0.0257 0.0297
Echinococcus granulosus integrin alpha ps 0.0053 0.0561 0.1127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0098 0.0112
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0081 0.0267
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0098 0.0196
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0143 0.0143
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0143 0.1782
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0081 0.0188
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Schistosoma mansoni hypothetical protein 0.0035 0.0326 0.0654
Giardia lamblia Sugar-proton symporter 0.0014 0.006 0.1002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0098 0.0113
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0098 0.0112
Toxoplasma gondii hypothetical protein 0.0026 0.0213 0.1359
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.1635 0.3282
Onchocerca volvulus 0.0028 0.0235 0.069
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0409 0.311
Onchocerca volvulus 0.0053 0.0558 0.1638
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0326 0.0654
Schistosoma mansoni hypothetical protein 0.0102 0.1181 0.2371
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Schistosoma mansoni intermediate filament proteins 0.0026 0.0213 0.0428
Brugia malayi putative neuropeptide receptor NPR1 0.0014 0.0055 0.0063
Echinococcus granulosus nAChR subunit 0.0122 0.1436 0.2881
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0558 0.0814
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0236 0.4714
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0075 0.0075
Brugia malayi GnHR receptor homolog 0.0014 0.0055 0.0063
Schistosoma mansoni hypothetical protein 0.0026 0.0205 0.0411
Echinococcus multilocularis protocadherin 11 0.0011 0.0018 0.0018
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0409 0.0585
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0098 0.0196
Echinococcus multilocularis solute carrier family 22 0.0014 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0143 0.0164
Trypanosoma brucei glucose transporter, putative 0.0032 0.0281 0.5749
Trypanosoma brucei glucose transporter, putative 0.0032 0.0281 0.5749
Onchocerca volvulus 0.0014 0.0055 0.0161
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.006 0.0069
Brugia malayi hypothetical protein 0.0056 0.0596 0.0687
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Onchocerca volvulus 0.0014 0.0055 0.0161
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0056 0.0113
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0201 0.1259
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0852 0.1709
Echinococcus granulosus alpha 1A adrenergic receptor 0.0014 0.0055 0.011
Schistosoma mansoni survival motor neuron protein 0.0047 0.0479 0.0961
Onchocerca volvulus 0.0014 0.0055 0.0161
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0056 0.0596 0.1196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0438 0.063
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.006 0.0684
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Schistosoma mansoni biogenic amine (5HT) receptor 0.0014 0.0055 0.011
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1181 0.2371
Schistosoma mansoni nAChR subunit 0.0122 0.1436 0.2881
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0014 0.0055 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0098 0.0113
Loa Loa (eye worm) hypothetical protein 0.0119 0.1406 0.1622
Echinococcus granulosus solute carrier family 22 0.0014 0.006 0.0121
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0438 0.0879
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Schistosoma mansoni neuropeptide F-like receptor 0.0014 0.0055 0.011
Echinococcus granulosus jun protein 0.035 0.4373 0.8776
Schistosoma mansoni hypothetical protein 0.0285 0.3531 0.7086
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0143 0.1782
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0338 0.7054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0253 0.0346
Mycobacterium ulcerans putative regulatory protein 0.0151 0.1817 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0014 0.0055 0.011
Onchocerca volvulus 0.0014 0.006 0.0177
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Onchocerca volvulus Huntingtin homolog 0.0119 0.1406 0.4127
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0447 0.0447
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0122 0.1436 0.1436
Loa Loa (eye worm) acetylcholine receptor protein 0.0056 0.0596 0.0687
Mycobacterium tuberculosis Probable reductase 0.0105 0.1223 0.8856
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0338 0.0679
Onchocerca volvulus 0.0014 0.006 0.0177
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0014 0.0055 0.0055
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0081 0.0285
Schistosoma mansoni hypothetical protein 0.033 0.4104 0.8237
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.1349 0.2707
Onchocerca volvulus Protein ultraspiracle homolog 0.0017 0.0098 0.0286
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0014 0.0055 0.011
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0014 0.0055 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0209 0.0278
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.035 0.4373 0.8776
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0098 0.0113
Brugia malayi Integrin alpha cytoplasmic region family protein 0.009 0.1032 0.119
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0294 0.2085
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0796 0.1598
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0143 0.0286
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0098 0.0196
Entamoeba histolytica hypothetical protein 0.0065 0.0717 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0014 0.0055 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0558 0.0814
Schistosoma mansoni adenoreceptor 0.0014 0.0055 0.011
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0141 0.2103
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0365 0.496
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0098 0.0113
Brugia malayi ORL1-like opioid receptor 0.0014 0.0055 0.0063
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.011 0.1819
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0257 0.0257
Loa Loa (eye worm) ACC-1 protein 0.0122 0.1436 0.1656
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0036
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0098 0.0196
Brugia malayi hypothetical protein 0.001 0.0000037341 0.0000043063
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.1181 1
Brugia malayi Dopamine receptor protein 2 0.0014 0.0055 0.0063
Schistosoma mansoni acetylcholine receptor subunit beta 0.0056 0.0596 0.1196
Loa Loa (eye worm) hypothetical protein 0.0013 0.0039 0.0045
Onchocerca volvulus 0.0014 0.006 0.0177
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0081 0.0163
Brugia malayi hypothetical protein 0.0014 0.006 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0056 0.0065
Onchocerca volvulus 0.0014 0.006 0.0177
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0338 0.0338
Echinococcus multilocularis allatostatin A receptor 0.0014 0.0055 0.0055
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0081 0.0966
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0141 0.0723
Onchocerca volvulus 0.0011 0.0018 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0212 0.0283
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0516 0.0516
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0338 0.039
Echinococcus multilocularis fmrfamide receptor 0.0014 0.0055 0.0055
Schistosoma mansoni nAChR subunit 0.0122 0.1436 0.2881
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.006 0.0167
Echinococcus multilocularis neuropeptide FF receptor 2 0.0014 0.0055 0.0055
Plasmodium falciparum importin beta, putative 0.0028 0.0236 0.1569
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0098 0.0113
Trypanosoma brucei glucose transporter, putative 0.0032 0.0281 0.5749
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0281 0.039
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0098 0.0196
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0039 0.0039
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0065 0.0655
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus granulosus aryl hydrocarbon receptor 0.0053 0.0558 0.112
Echinococcus granulosus dro:myosuppressin receptor 0.0014 0.0055 0.011
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.006 0.006
Schistosoma mansoni transcriptional factor nfil3/e4bp4 0.0011 0.0018 0.0036
Schistosoma mansoni neuropeptide receptor 0.0014 0.0055 0.011
Brugia malayi bZIP transcription factor family protein 0.001 0.0000037341 0.0000043063
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0098 0.0113
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0098 0.0196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.018 0.0234
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1181 0.2371
Brugia malayi bZIP transcription factor family protein 0.035 0.4373 0.5043
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0213 0.0246
Leishmania major hypothetical protein, conserved 0.0014 0.006 0.0566
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0201 0.4366
Brugia malayi Hepatic leukemia factor 0.0011 0.0018 0.0021
Brugia malayi hypothetical protein 0.0025 0.0191 0.0221
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Brugia malayi ABC transporter family protein 0.0021 0.0143 0.0165
Echinococcus multilocularis transfer RNA-Lys 0.0151 0.1817 0.1817
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0281 0.039
Echinococcus granulosus sex peptide receptor 0.0014 0.0055 0.011
Onchocerca volvulus 0.003 0.0257 0.0755
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0447 0.0515
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0098 0.0196
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0014 0.0055 0.0063
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0065 0.0655
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0021
Brugia malayi ecdysteroid receptor 0.0017 0.0098 0.0113
Loa Loa (eye worm) hypothetical protein 0.0025 0.0191 0.0221
Echinococcus granulosus somatostatin receptor 0.0014 0.0055 0.011
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0338 0.5838
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0212 0.0283
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0098 0.0196
Loa Loa (eye worm) bZIP transcription factor family protein 0.0011 0.0018 0.0021
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0014 0.0055 0.011
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Echinococcus multilocularis integrin alpha 3 0.0026 0.0205 0.0205
Brugia malayi hypothetical protein 0.0686 0.8671 1
Leishmania major glucose transporter, lmgt2 0.0032 0.0281 0.4758
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0122 0.1436 0.1656
Echinococcus multilocularis GPCR, family 2 0.0015 0.0075 0.0075
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0053 0.0558 0.112
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Brugia malayi RNA, U transporter 1 0.008 0.0899 0.1037
Echinococcus multilocularis integrin alpha ps 0.0026 0.0205 0.0205
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0143 0.0177
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0438 0.7721
Leishmania major importin beta-1 subunit, putative 0.0023 0.0168 0.2613
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0098 0.1281
Echinococcus granulosus neuropeptide receptor A26 0.0014 0.0055 0.011
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0558 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0179 0.0233
Plasmodium vivax importin-beta 2, putative 0.0028 0.0236 0.1569
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0053 0.0558 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.0596 0.0687
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0123 0.0123
Brugia malayi neuropeptide F receptor 0.0014 0.0055 0.0063
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0098 0.0196
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0213 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0323 0.0453
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0447 0.0897
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0056 0.0596 0.0687
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0122 0.1436 0.2881
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0014 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.1436 0.1656
Schistosoma mansoni hypothetical protein 0.0015 0.0075 0.015
Echinococcus multilocularis neuropeptide s receptor 0.0014 0.0055 0.0055
Echinococcus granulosus hypothetical protein 0.0014 0.0055 0.011
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.003 0.0035
Echinococcus granulosus neuropeptide s receptor 0.0014 0.0055 0.011
Echinococcus multilocularis neuropeptides capa receptor 0.0014 0.0055 0.0055
Echinococcus granulosus integrin alpha 3 0.0026 0.0205 0.0411
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0014 0.0055 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0081 0.0966
Brugia malayi bZIP transcription factor family protein 0.001 0.0000037341 0.0000043063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0447 0.0447
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0143 0.0735
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0065 0.0792
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0122 0.1436 0.2881
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0001 0.0003
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0065 0.013
Loa Loa (eye worm) hypothetical protein 0.0076 0.0852 0.0982
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0122 0.1436 0.2881
Onchocerca volvulus 0.0014 0.0055 0.0161
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Onchocerca volvulus 0.0014 0.006 0.0177
Trypanosoma brucei trypanothione reductase 0.0046 0.0467 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0081 0.1168
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.1436 0.1656
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0852 0.7058
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0191 0.3053
Loa Loa (eye worm) hypothetical protein 0.0026 0.0205 0.0236
Trichomonas vaginalis set domain proteins, putative 0.0231 0.2842 0.4316
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0143 0.0177
Trypanosoma brucei glucose transporter, putative 0.0032 0.0281 0.5749
Schistosoma mansoni amine GPCR 0.0014 0.0055 0.011
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0056 0.0596 0.0687
Trypanosoma cruzi glucose transporter, putative 0.0014 0.006 0.0566
Brugia malayi Importin beta-1 subunit 0.0028 0.0236 0.0272
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0143 0.0177
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0122 0.1436 0.2881
Trichomonas vaginalis ran, putative 0.0021 0.0141 0.0175
Brugia malayi hypothetical protein 0.0056 0.0596 0.0687
Schistosoma mansoni ran 0.0021 0.0141 0.0284
Schistosoma mansoni par domain protein 0.0011 0.0018 0.0036
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0122 0.1436 0.1436
Brugia malayi major facilitator superfamily protein 0.0014 0.006 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Schistosoma mansoni hypothetical protein 0.0299 0.3714 0.7453
Trichomonas vaginalis abcb9, putative 0.0021 0.0143 0.0177
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0467 0.0937
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0143 0.0286
Loa Loa (eye worm) LGC-31 protein 0.0122 0.1436 0.1656
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0014 0.0055 0.0055
Echinococcus granulosus Ankyrin 0.0014 0.0058 0.0116
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.1374 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0281 0.5749
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0098 0.0196
Brugia malayi Dopamine receptor 0.0014 0.0055 0.0063
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0516 0.2611
Loa Loa (eye worm) acetyltransferase 0.0141 0.1686 0.1945
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0122 0.1436 0.1656
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0018 0.0036
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0213 0.0246
Echinococcus granulosus X box binding protein 1 0.0011 0.0018 0.0036
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0017 0.0098 0.0286
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0479 0.0552
Schistosoma mansoni hypothetical protein 0.0033 0.0305 0.0612
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0065 0.0058
Echinococcus granulosus flap endonuclease 1 0.0025 0.0201 0.0404
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0212 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0294 0.0409
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0438 0.063
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0141 0.0284
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0143 0.0177
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0081 0.0966
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0141 0.2934
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus multilocularis integrin alpha ps 0.0053 0.0561 0.0561
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0143 0.0177
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Loa Loa (eye worm) hypothetical protein 0.0028 0.0233 0.0269
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0098 0.0196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0338 0.0477
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0056 0.0596 0.1196
Echinococcus granulosus biogenic amine 5HT receptor 0.0014 0.0055 0.011
Echinococcus granulosus serotonin receptor 0.0014 0.0055 0.011
Onchocerca volvulus 0.0014 0.006 0.0177
Schistosoma mansoni jun-related protein 0.0285 0.3531 0.7086
Onchocerca volvulus 0.0014 0.0055 0.0161
Loa Loa (eye worm) glutathione reductase 0.0046 0.0467 0.0539
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0122 0.1436 0.1656
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0014 0.0055 0.0055
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0017 0.0098 0.0196
Echinococcus multilocularis lamin dm0 0.0026 0.0213 0.0213
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0098 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.018 0.0234
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0141 0.2103
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0056 0.0165
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0201 0.0232
Loa Loa (eye worm) integrin alpha pat-2 0.0118 0.1388 0.1601
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0122 0.1436 0.1436
Brugia malayi hypothetical protein 0.0016 0.008 0.0092
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0081 0.0188
Brugia malayi Cytochrome P450 family protein 0.0012 0.003 0.0035
Echinococcus multilocularis ccaat enhancer binding protein delta ccaat enhancer binding protein beta 0.0011 0.0018 0.0018
Echinococcus granulosus peptide allatostatin:somatostatin 0.0014 0.0055 0.011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0021
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0122 0.1436 0.1656
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0122 0.1436 0.2881
Brugia malayi neuropeptide F receptor 0.0014 0.0055 0.0063
Loa Loa (eye worm) cell death specification protein 2 0.0011 0.0018 0.0021
Leishmania major hypothetical protein, conserved 0.0025 0.0191 0.3053
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0122 0.1436 0.2881
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0053 0.0558 0.0814
Loa Loa (eye worm) hypothetical protein 0.0119 0.1406 0.1622
Echinococcus granulosus geminin 0.033 0.4104 0.8237
Echinococcus granulosus g-protein coupled receptor 0.0014 0.0055 0.011
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0213 0.1359
Trichomonas vaginalis abcb9, putative 0.0021 0.0143 0.0177
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0014 0.0055 0.0055
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0143 0.0735
Schistosoma mansoni amine GPCR 0.0014 0.0055 0.011
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0081 0.0267
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0257 0.0257
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0143 0.0143
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0065 0.0717 0.0826
Schistosoma mansoni glucose transporter 0.0014 0.006 0.0121
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0055 0.011
Onchocerca volvulus 0.0014 0.0055 0.0161
Trypanosoma brucei glucose transporter, putative 0.0032 0.0281 0.5749
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0143 0.0286
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0098 0.0098
Echinococcus multilocularis somatostatin receptor 0.0014 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0323 0.0453
Brugia malayi Tachykinin-like peptides receptor 99D 0.0014 0.0055 0.0063
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1181 0.2371
Schistosoma mansoni biogenic amine receptor 0.0014 0.0055 0.011
Schistosoma mansoni nAChR subunit 0.0122 0.1436 0.2881
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0081 0.0285
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.1349 0.1349
Schistosoma mansoni hypothetical protein 0.0014 0.0056 0.0113
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0056 0.0065
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0075 0.0086
Echinococcus multilocularis serotonin receptor 0.0014 0.0055 0.0055
Echinococcus multilocularis thyroid hormone receptor alpha 0.0017 0.0098 0.0098
Schistosoma mansoni nAChR subunit 0.0122 0.1436 0.2881
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0112
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0112
Onchocerca volvulus 0.0014 0.006 0.0177
Schistosoma mansoni retinoic acid receptor RXR 0.0017 0.0098 0.0196
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0305 0.0352
Brugia malayi hypothetical protein 0.0056 0.0596 0.0687
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0236 0.0473
Echinococcus multilocularis lamin 0.0026 0.0213 0.0213
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0338 0.5838
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0143 0.0177
Brugia malayi bZIP transcription factor family protein 0.001 0.0000037341 0.0000043063
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0281 0.4758
Schistosoma mansoni myosin xvIII 0.0014 0.0055 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.1181 0.177
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0098 0.0113
Echinococcus granulosus g protein coupled receptor 0.0014 0.0055 0.011
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Loa Loa (eye worm) melatonin receptor type 1A 0.0014 0.0055 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.006 0.005
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0053 0.0558 0.0558
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0081 0.0966
Brugia malayi hypoxia-induced factor 1 0.0632 0.799 0.9214
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0081 0.1168
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0065 0.0075
Schistosoma mansoni hypothetical protein 0.0014 0.0055 0.011
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0014 0.0055 0.0063
Onchocerca volvulus 0.0056 0.0596 0.1749
Brugia malayi hypothetical protein 0.0011 0.0018 0.0021
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1181 0.2371
Loa Loa (eye worm) hypothetical protein 0.0036 0.0338 0.039
Schistosoma mansoni growth hormone secretagogue receptor 0.0014 0.0055 0.011
Onchocerca volvulus 0.0014 0.0055 0.0161
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0014 0.0055 0.0063
Leishmania major trypanothione reductase 0.0046 0.0467 0.8276
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Brugia malayi PAS domain containing protein 0.0204 0.2498 0.2881
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0852 0.7058
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0053 0.0558 0.0814
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0055 0.0055
Schistosoma mansoni sugar transporter 0.0014 0.006 0.0121
Loa Loa (eye worm) neuropeptide F receptor 0.0014 0.0055 0.0063
Echinococcus multilocularis g-protein coupled receptor 0.0014 0.0055 0.0055
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0143 0.2128
Plasmodium vivax SET domain protein, putative 0.003 0.0257 0.1757
Schistosoma mansoni multidrug resistance protein 0.0021 0.0143 0.0286
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0021
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.1686 0.3384
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0143 0.1782
Entamoeba histolytica hypothetical protein 0.0035 0.0326 0.4406
Echinococcus granulosus g protein coupled receptor 0.0014 0.0055 0.011
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0053 0.0558 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Echinococcus granulosus neuropeptide receptor 0.0014 0.0055 0.011
Brugia malayi bZIP transcription factor family protein 0.001 0.0000037341 0.0000043063
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0065 0.0717 0.0826
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0098 0.0113
Echinococcus granulosus fmrfamide receptor 0.0014 0.0055 0.011
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0036
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0191 0.117
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0122 0.1436 0.2881
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.2483 0.2863
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0011 0.0018 0.0036
Brugia malayi hypothetical protein 0.0011 0.0018 0.0021
Schistosoma mansoni biogenic amine receptor 0.0014 0.0055 0.011
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.035 0.4373 0.4373
Brugia malayi sulfakinin receptor protein 0.0014 0.0055 0.0063
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.006 0.0167
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0014 0.0055 0.011
Brugia malayi multidrug resistance protein 3 0.0021 0.0143 0.0165
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0122 0.1436 0.1656
Plasmodium vivax hexose transporter 0.0102 0.1181 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0014 0.0055 0.011
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.006 0.0566
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0143 0.0177
Onchocerca volvulus 0.0014 0.0055 0.0161
Loa Loa (eye worm) hypothetical protein 0.0012 0.0033 0.0038
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.1223 0.8856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0241 0.0328
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0438 0.933
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0558 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0014 0.0055 0.011
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0053 0.0558 0.0814
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0081 0.0083
Echinococcus granulosus biogenic amine 5HT receptor 0.0014 0.0055 0.011
Brugia malayi larval opioid receptor 0.0014 0.0055 0.0063
Trypanosoma brucei glucose transporter, putative 0.0032 0.0281 0.5749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0356 0.0504
Echinococcus granulosus rhodopsin orphan GPCR 0.0014 0.0055 0.011
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0143 0.1782
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0055 0.0055
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0075 0.0086
Echinococcus granulosus ccaat enhancer binding protein delta 0.0011 0.0018 0.0036
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.002 0.014 0.028
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0281 0.039
Onchocerca volvulus 0.0014 0.0055 0.0161
Echinococcus multilocularis serotonin receptor 0.0014 0.0055 0.0055
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0191 0.3689
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0055 0.0055
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0326 0.0654
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0056 0.0596 0.0687
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0075 0.015
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0852 1
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0558 0.0814
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0143 0.0143
Echinococcus granulosus dnaJ subfamily B 0.0398 0.4983 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0191 0.117
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0122 0.1436 0.1436
Echinococcus granulosus RUN 0.0019 0.0123 0.0247
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0098 0.0112
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0281 0.5749
Echinococcus multilocularis nAChR subunit 0.0065 0.0717 0.0717
Schistosoma mansoni hypothetical protein 0.0014 0.0055 0.011
Schistosoma mansoni amine GPCR 0.0175 0.2123 0.426
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0081 0.0188
Schistosoma mansoni aryl hydrocarbon receptor 0.0204 0.2498 0.5013
Schistosoma mansoni netrin receptor unc5 0.0014 0.0056 0.0113
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0852 0.4597
Schistosoma mansoni glucose transport protein 0.0102 0.1181 0.2371
Loa Loa (eye worm) STAT protein 0.0128 0.1519 0.1751
Leishmania major glucose transporter, lmgt3 0.0032 0.0281 0.4758
Plasmodium falciparum glutathione reductase 0.0046 0.0467 0.3629
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Echinococcus multilocularis Ankyrin 0.0014 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Mycobacterium ulcerans sugar transporter 0.0014 0.006 0.0167
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0014 0.0055 0.011
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0338 0.0338
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0409 0.311
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0056 0.0065
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0338 0.7632
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0065 0.0075
Onchocerca volvulus 0.0014 0.0055 0.0161
Echinococcus multilocularis X box binding protein 1 0.0011 0.0018 0.0018
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0614 0.494
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Onchocerca volvulus 0.0122 0.1436 0.4213
Onchocerca volvulus 0.0122 0.1436 0.4213
Echinococcus granulosus GPCR family 2 0.0015 0.0075 0.015
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0014 0.0055 0.011
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0122 0.1436 0.2881
Brugia malayi Cell death specification protein 2 0.0011 0.0018 0.0021
Onchocerca volvulus 0.0151 0.1817 0.5332
Schistosoma mansoni glucose transport protein 0.0102 0.1181 0.2371
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0438 0.7721
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0062 0.0125
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Schistosoma mansoni sugar transporter 0.0014 0.006 0.0121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0236 0.0272
Echinococcus multilocularis solute carrier family 22 0.0014 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0014 0.0055 0.011
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0467 0.8276
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0015 0.0075 0.015
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0014 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0438 0.063
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0123 0.0559
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0201 0.3916
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Schistosoma mansoni lamin 0.0026 0.0213 0.0428
Brugia malayi G-protein coupled receptor 0.0014 0.0055 0.0063
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0516 0.3468
Schistosoma mansoni neurotransmitter gated ion channel 0.0056 0.0596 0.1196
Brugia malayi steroid hormone receptor 0.0017 0.0098 0.0113
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0143 0.0177
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0201 0.0201
Entamoeba histolytica Ran family GTPase 0.0021 0.0141 0.1763
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.4983 0.4983
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.1374 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Brugia malayi hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Loa Loa (eye worm) hypothetical protein 0.0019 0.0123 0.0142
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0122 0.1436 0.1436
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0011 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0098 0.0196
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0143 0.0177
Schistosoma mansoni loxhd1 0.0019 0.0123 0.0247
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0281 0.4758
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Echinococcus granulosus tachykinin peptides receptor 99D 0.0014 0.0055 0.011
Schistosoma mansoni neuropeptide f receptor 76f 0.0014 0.0055 0.011
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0338 0.0679
Echinococcus multilocularis dro:myosuppressin receptor 0.0014 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0323 0.0453
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Echinococcus granulosus integrin alpha ps 0.0026 0.0205 0.0411
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0081 0.1168
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0036
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0056 0.0056
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0056 0.0596 0.0596
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0122 0.1436 0.1656
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0143 0.1782
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0053 0.0558 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0122 0.1436 0.2881
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0213 0.1359
Schistosoma mansoni ran 0.0021 0.0141 0.0284
Schistosoma mansoni lipoxygenase 0.008 0.0906 0.1818
Echinococcus multilocularis nAChR subunit 0.0122 0.1436 0.1436
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0021
Echinococcus multilocularis neuropeptide receptor 0.0014 0.0055 0.0055
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0098 0.0098
Brugia malayi STAT protein, DNA binding domain containing protein 0.0128 0.1519 0.1751
Schistosoma mansoni nAChR subunit 0.0122 0.1436 0.2881
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0065 0.0717 0.1438
Echinococcus multilocularis sex peptide receptor 0.0014 0.0055 0.0055
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0143 0.0177
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0055 0.0055
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0201 0.0267
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0055 0.0055
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0236 0.1569
Echinococcus granulosus solute carrier family 22 0.0014 0.006 0.0121
Echinococcus multilocularis snurportin 1 0.0299 0.3714 0.3714
Loa Loa (eye worm) hypothetical protein 0.0015 0.0075 0.0086
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0053 0.0558 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0098 0.0098
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0438 0.6008
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0143 0.0143
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0143 0.0164
Brugia malayi hypothetical protein 0.0011 0.0018 0.0021
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0014 0.0055 0.0055
Echinococcus multilocularis neuropeptide receptor 0.0014 0.0055 0.0055
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0143 0.0143
Plasmodium vivax glutathione reductase, putative 0.0046 0.0467 0.3629
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.3714 0.4283
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0098 0.0113
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0143 0.0143
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0065 0.0717 0.0826
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0122 0.1436 0.1656
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0409 0.311
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0098 0.0112
Loa Loa (eye worm) hypoxia-induced factor 1 0.0632 0.799 0.9214
Loa Loa (eye worm) hypothetical protein 0.0341 0.425 0.4901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0065 0.0058
Entamoeba histolytica hypothetical protein 0.0035 0.0326 0.4406
Schistosoma mansoni cpg binding protein 0.003 0.0256 0.0513
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0123 0.0123
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0338 0.0679
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0122 0.1436 0.1656
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0065 0.0792
Loa Loa (eye worm) hypothetical protein 0.0056 0.0596 0.0687
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Trichomonas vaginalis conserved hypothetical protein 0.052 0.6548 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0143 0.0177
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0409 0.082
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0014 0.0055 0.0063
Trypanosoma brucei glucose transporter 1E 0.0032 0.0281 0.5749
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0323 0.6712
Schistosoma mansoni neuropeptide receptor 0.0014 0.0055 0.011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.018 0.0234
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0018 0.0018
Echinococcus granulosus neuropeptide Y receptor 0.0014 0.0055 0.011
Brugia malayi Doublecortin family protein 0.0019 0.0123 0.0142
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0438 0.0505
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0651 0.1306
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0141 0.2541
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0014 0.0055 0.011
Echinococcus multilocularis neuropeptide Y receptor 0.0014 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0326 0.0326
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0014 0.0055 0.011
Echinococcus multilocularis neuropeptide Y receptor 0.0014 0.0055 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0081 0.0966
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0281 0.039
Schistosoma mansoni hypothetical protein 0.0015 0.0075 0.015
Onchocerca volvulus 0.0017 0.0098 0.0286
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0098 0.0196
Echinococcus granulosus glycine receptor subunit alpha 1 0.0122 0.1436 0.2881
Trichomonas vaginalis sugar transporter, putative 0.0014 0.006 0.005
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0143 0.0177
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0027 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.014 0.0161
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0365 0.2714
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0796 0.0796
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.1181 0.1181
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0236 0.4714
Loa Loa (eye worm) hypothetical protein 0.0017 0.0098 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0065 0.0058
Loa Loa (eye worm) TYRA-2 protein 0.0014 0.0055 0.0063
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0438 0.6008
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0122 0.1436 0.1436
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0201 0.3241
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0098 0.0196
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0123 0.0247
Loa Loa (eye worm) hypothetical protein 0.0065 0.0717 0.0826
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0056 0.0596 0.0687
Loa Loa (eye worm) hypothetical protein 0.023 0.2829 0.3262
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0053 0.0558 0.6189
Echinococcus multilocularis rhodopsin orphan GPCR 0.0014 0.0055 0.0055
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0014 0.0055 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0014 0.0055 0.011
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0143 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.052 0.6548 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0014 0.0055 0.011
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0014 0.0055 0.0055
Brugia malayi Sugar transporter family protein 0.0014 0.006 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0257 0.0516
Loa Loa (eye worm) hypothetical protein 0.0014 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0122 0.1436 0.1656
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.006 0.0069
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0852 1

Activities

Activity type Activity value Assay description Source Reference
AC50 (binding) = 0.8 uM Induction of CHOP (unknown origin) expressed in CHOK1 cells by luciferase reporter gene assay ChEMBL. 25530830
AC50 (binding) > 80 uM Induction of XBP1 (unknown origin) expressed in CHOK1 cells by luciferase reporter gene assay ChEMBL. 25530830
EC50 (functional) = 4.8 uM Antiproliferative activity against wild-type MEF cells after 16 hrs by luminescence assay ChEMBL. 25530830
EC50 (functional) > 20 uM Antiproliferative activity against CHOP-knock out MEF cells after 16 hrs by luminescence assay ChEMBL. 25530830
Inhibition (binding) = 68 % Displacement of [125I] RTI-55 from human recombinant DAT expressed in CHOK1 cells after 3 hrs ChEMBL. 25530830
PPB (ADMET) > 99 % Plasma protein binding in human plasma after 4 hrs by LC/MS/MS method ChEMBL. 25530830

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 25530830

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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