Detailed information for compound 1277310

Basic information

Technical information
  • TDR Targets ID: 1277310
  • Name: 1-Bromo-4-methylbenzene
  • MW: 171.034 | Formula: C7H7Br
  • H donors: 0 H acceptors: 0 LogP: 2.98 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)Br
  • InChi: 1S/C7H7Br/c1-6-2-4-7(8)5-3-6/h2-5H,1H3
  • InChiKey: ZBTMRBYMKUEVEU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-bromo-4-methyl-benzene
  • 106-38-7
  • 4-Methylbromobenzene
  • Benzene, 1-bromo-4-methyl-
  • NSC6531
  • Toluene, p-bromo-
  • p-Bromotoluene
  • p-Methylbromobenzene
  • p-Methylphenyl bromide
  • p-Tolyl bromide
  • NCGC00090876-01
  • InChI=1/C7H7Br/c1-6-2-4-7(8)5-3-6/h2-5H,1H
  • 4-Methylphenyl bromide
  • 4-Tolyl bromide
  • AI3-28596
  • CCRIS 5983
  • EINECS 203-391-8
  • HSDB 6015
  • NSC 6531
  • Parabromotoluene
  • Toluene, 4-bromo-
  • ST5214480
  • 18510_FLUKA
  • B82200_ALDRICH
  • 1-Methyl-4-bromobenzene
  • 4-Bromo-1-methylbenzene
  • 4-Bromotoluene
  • 4-Methyl-1-bromobenzene

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens androgen receptor Starlite/ChEMBL No references
Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0147 0.0913
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0375 0.1464 1
Plasmodium vivax hypothetical protein, conserved 0.008 0.0264 0.1718
Loa Loa (eye worm) tyrosyl-tRNA synthetase 0.0038 0.0092 0.0092
Schistosoma mansoni zinc finger protein 0.0016 0.0002 0.0002
Toxoplasma gondii dgat2l1-prov protein 0.0558 0.2207 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0242 0.0924 0.0924
Onchocerca volvulus Huntingtin homolog 0.0122 0.0434 0.1923
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0063 0.0194 0.0194
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0067 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0012 0.0012
Loa Loa (eye worm) methionyl-tRNA synthetase 0.0061 0.0187 0.0187
Schistosoma mansoni methionine-tRNA synthetase 0.0061 0.0187 0.0187
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0187 0.0787
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0088 0.0088
Loa Loa (eye worm) MBOAT family protein 0.0063 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0063 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.016 0.0717
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0347 0.0347
Trichomonas vaginalis transmembrane protein nessy, putative 0.0063 0.0194 0.0965
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0012 0.0012
Mycobacterium tuberculosis Conserved protein 0.008 0.0264 0.1242
Leishmania major glycerol uptake protein, putative 0.0063 0.0194 0.0873
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0054 0.0223
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0264 0.1333
Leishmania major leucyl-tRNA synthetase, putative 0.0023 0.0033 0.0141
Schistosoma mansoni sterol O-acyltransferase 1 0.0063 0.0194 0.0194
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0194 0.0194
Wolbachia endosymbiont of Brugia malayi methionyl-tRNA synthetase 0.0061 0.0187 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.008 0.0264 0.0263
Toxoplasma gondii tRNA ligases class I (M) protein 0.0023 0.0033 0.0083
Loa Loa (eye worm) hypothetical protein 0.0039 0.0098 0.0098
Loa Loa (eye worm) MBOAT family protein 0.0063 0.0194 0.0194
Echinococcus multilocularis sterol O acyltransferase 1 0.0063 0.0194 0.0194
Toxoplasma gondii ABC1 family protein 0.008 0.0264 0.1136
Toxoplasma gondii thioredoxin reductase 0.0055 0.016 0.0662
Schistosoma mansoni alpha-13-mannosyl-glycoprotein beta-1 2-n-acetylglucosaminyltransferase 0.0106 0.037 0.037
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0375 0.1464 0.1464
Mycobacterium ulcerans lipase LipD 0.008 0.0264 0.5849
Giardia lamblia Methionyl-tRNA synthetase 0.0061 0.0187 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0012 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0242 0.0924 0.0924
Chlamydia trachomatis leucine--tRNA ligase 0.0023 0.0033 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0024 0.0065
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0063 0.0194 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0827 0.4321
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0024 0.0024
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.2473 1 1
Brugia malayi Bromodomain containing protein 0.0079 0.0258 0.0258
Brugia malayi MBOAT family protein 0.0063 0.0194 0.0194
Mycobacterium ulcerans hypothetical protein 0.0124 0.044 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0009 0.0009
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.0264 0.0264
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0015 0.0014
Mycobacterium leprae conserved hypothetical protein 0.008 0.0264 0.2439
Toxoplasma gondii exonuclease III APE 0.0021 0.0024 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0194 0.0194
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0063 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Brugia malayi Pax transcription factor protein 2 0.0272 0.1044 0.1043
Echinococcus granulosus dnaJ subfamily B 0.0407 0.1595 0.1595
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0347 0.0347
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0031 0.0031
Treponema pallidum methionyl-tRNA synthetase 0.0023 0.0033 0.1019
Schistosoma mansoni zinc finger protein 0.0022 0.0026 0.0026
Onchocerca volvulus 0.008 0.0264 0.1146
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0015 0.0059
Schistosoma mansoni hypothetical protein 0.0032 0.0067 0.0067
Mycobacterium leprae Probable lipase LipE 0.008 0.0264 0.2439
Schistosoma mansoni bromodomain containing protein 0.0067 0.0209 0.0209
Entamoeba histolytica hypothetical protein, conserved 0.0063 0.0194 0.4456
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0147 0.0658
Loa Loa (eye worm) hhat protein 0.0063 0.0194 0.0194
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0242 0.0924 0.0924
Trichomonas vaginalis porcupine, putative 0.0063 0.0194 0.0965
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0067 0.0067
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0063 0.0194 0.4456
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0009 0.0009
Plasmodium falciparum glutathione reductase 0.0055 0.016 0.1001
Schistosoma mansoni ap endonuclease 0.0021 0.0024 0.0024
Toxoplasma gondii mono- or diacylglycerol acyltransferase 0.0124 0.044 0.1942
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0024 0.0101
Echinococcus multilocularis chromobox protein 1 0.0072 0.0231 0.0231
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0231 0.1162
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0115 0.0406 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0012 0.0012
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0063 0.0194 0.0194
Brugia malayi nuclear receptor NHR-88 0.0018 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0115 0.0406 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.0434 0.0434
Brugia malayi Pre-SET motif family protein 0.0424 0.1661 0.1661
Onchocerca volvulus 0.0558 0.2207 1
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0194 0.0965
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0067 0.0067
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0194 0.0194
Brugia malayi MBOAT family protein 0.0063 0.0194 0.0194
Mycobacterium tuberculosis Probable hydrolase 0.008 0.0264 0.1242
Loa Loa (eye worm) hypothetical protein 0.0042 0.0108 0.0108
Schistosoma mansoni transcription factor LCR-F1 0.0115 0.0406 0.0406
Schistosoma mansoni hypothetical protein 0.0407 0.1595 0.1595
Schistosoma mansoni chromobox protein 0.0072 0.0231 0.0231
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0138 0.0501 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0012 0.0012
Brugia malayi methionyl-tRNA synthetase 0.0023 0.0033 0.0033
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0063 0.0194 0.0194
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0063 0.0194 0.0194
Echinococcus granulosus o acyltransferase membrane bound domain 0.0063 0.0194 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0264 0.1188
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0125 0.0444 0.2142
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0242 0.0924 0.0924
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0012 0.0012
Toxoplasma gondii diacylglycerol acyltransferase 0.0124 0.044 0.1942
Trypanosoma cruzi glycerol uptake protein, putative 0.0063 0.0194 0.0873
Trichomonas vaginalis esterase, putative 0.008 0.0264 0.1333
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0218 0.0217
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0015 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0012 0.0012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0012 0.0012
Toxoplasma gondii hypothetical protein 0.0063 0.0194 0.0819
Onchocerca volvulus 0.0073 0.0235 0.1016
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0063 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0033
Echinococcus granulosus chromobox protein 1 0.0072 0.0231 0.0231
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0012 0.0012
Echinococcus multilocularis GPCR, family 2 0.0032 0.0067 0.0067
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0012 0.0012
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0023 0.0033 0.0231
Loa Loa (eye worm) glutathione reductase 0.0055 0.016 0.0159
Echinococcus granulosus histone lysine methyltransferase setb 0.0079 0.0258 0.0258
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0067 0.0067
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0138 0.0501 0.2424
Brugia malayi ecdysteroid receptor 0.0018 0.0012 0.0012
Brugia malayi GNT-I family protein 0.0106 0.037 0.0369
Mycobacterium tuberculosis Probable conserved lipoprotein 0.008 0.0264 0.1242
Loa Loa (eye worm) beta-lactamase 0.008 0.0264 0.0263
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0242 0.0924 0.0924
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0106 0.037 0.0369
Brugia malayi chromobox protein homolog 3 0.004 0.0102 0.0102
Onchocerca volvulus 0.0482 0.1899 0.8597
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Mycobacterium ulcerans esterase/lipase LipP 0.008 0.0264 0.5849
Treponema pallidum leucyl-tRNA synthetase 0.0023 0.0033 0.1019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0187 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0827 0.4321
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0174 0.0647 0.0647
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0063 0.0194 0.0194
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.008 0.0264 0.1242
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.1661 0.1661
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0347 0.0347
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0063 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0069 0.0218 0.0217
Echinococcus multilocularis chromobox protein 1 0.0072 0.0231 0.0231
Trypanosoma brucei trypanothione reductase 0.0055 0.016 0.0717
Leishmania major glycerol uptake protein, putative 0.0063 0.0194 0.0873
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0512 0.202 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0015 0.0059
Loa Loa (eye worm) hypothetical protein 0.0051 0.0147 0.0147
Leishmania major hypothetical protein, conserved 0.0063 0.0194 0.0873
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0115 0.0406 0.0405
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0015 0.0059
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0015 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0054 0.0223
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0558 0.2207 0.2207
Schistosoma mansoni hypothetical protein 0.0032 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0827 0.4321
Schistosoma mansoni hypothetical protein 0.0023 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.2473 1 1
Schistosoma mansoni hypothetical protein 0.0124 0.044 0.044
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0063 0.0194 0.4456
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0015 0.0059
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0012 0.0012
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0063 0.0194 0.0194
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0175 0.0175
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0125 0.0444 0.2142
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0009 0.0009
Plasmodium vivax glutathione reductase, putative 0.0055 0.016 0.1001
Toxoplasma gondii methionyl-tRNA synthetase 0.0061 0.0187 0.0787
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.048 0.2481
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0012 0.0012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0012 0.0012
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0015 0.0014
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0024 0.0047
Schistosoma mansoni cpg binding protein 0.0032 0.0069 0.0069
Plasmodium vivax methionine--tRNA ligase, putative 0.0023 0.0033 0.0126
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0115 0.0406 0.0405
Treponema pallidum alginate O-acetylation protein (algI) 0.0063 0.0194 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0024 0.0548
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0012 0.0012
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0024 0.0024
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0558 0.2207 0.2207
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0015 0.0059
Loa Loa (eye worm) zinc finger protein 0.0349 0.1359 0.1358
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0015 0.0059
Schistosoma mansoni hypothetical protein 0.0032 0.0067 0.0067
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0242 0.0924 0.0924
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0066
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0012 0.0012
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0125 0.0444 0.8197
Trypanosoma cruzi GUP1, putative 0.0063 0.0194 0.0873
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.008 0.0264 0.0263
Loa Loa (eye worm) hypothetical protein 0.0122 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.008 0.0264 0.0263
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0115 0.0406 0.0406
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.008 0.0264 0.0263
Mycobacterium tuberculosis Probable oxidoreductase 0.0138 0.0501 0.2424
Brugia malayi Thioredoxin reductase 0.0055 0.016 0.0159
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0177 0.0741
Echinococcus granulosus zinc finger protein 0.0022 0.0026 0.0026
Plasmodium falciparum thioredoxin reductase 0.0055 0.016 0.1001
Plasmodium falciparum methionine--tRNA ligase, putative 0.0023 0.0033 0.0126
Echinococcus granulosus sterol O acyltransferase 1 0.0063 0.0194 0.0194
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.2473 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0067 0.0067
Brugia malayi Zinc finger, C2H2 type family protein 0.0349 0.1359 0.1358
Brugia malayi Hhat protein 0.0063 0.0194 0.0194
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0115 0.0544
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0024 0.0101
Plasmodium vivax SET domain protein, putative 0.0061 0.0187 0.119
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0055 0.016 0.0724
Loa Loa (eye worm) pax transcription factor protein 2 0.0272 0.1044 0.1043
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0033 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0827 0.4321
Leishmania major glycerol uptake protein, putative 0.0063 0.0194 0.0873
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0015 0.0014
Onchocerca volvulus Huntingtin homolog 0.0122 0.0434 0.1923
Loa Loa (eye worm) thioredoxin reductase 0.0055 0.016 0.0159
Onchocerca volvulus 0.0063 0.0194 0.0829
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0039 0.0038
Toxoplasma gondii Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase 0.0036 0.0084 0.0318
Echinococcus granulosus o acyltransferase membrane bound domain 0.0063 0.0194 0.0194
Schistosoma mansoni coup transcription factor 0.0018 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0015 0.0059
Brugia malayi hypothetical protein 0.0115 0.0406 0.0405
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0012 0.0012
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0054 0.0054
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0242 0.0924 0.0924
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0102 0.0411
Loa Loa (eye worm) hypothetical protein 0.004 0.0102 0.0102
Schistosoma mansoni hypothetical protein 0.0069 0.0218 0.0218
Echinococcus multilocularis beta LACTamase domain containing family member 0.008 0.0264 0.0263
Onchocerca volvulus 0.0029 0.0054 0.0191
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0033
Brugia malayi Pre-SET motif family protein 0.0061 0.0187 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0102 0.0478
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0024 0.0024
Schistosoma mansoni cpg binding protein 0.0029 0.0054 0.0054
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0125 0.0444 0.2142
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0012 0.0012
Loa Loa (eye worm) MBOAT family protein 0.0063 0.0194 0.0194
Brugia malayi glutathione reductase 0.0055 0.016 0.0159
Loa Loa (eye worm) hypothetical protein 0.0101 0.0347 0.0347
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0375 0.1464 0.1464
Toxoplasma gondii hypothetical protein 0.0085 0.0285 0.1233
Loa Loa (eye worm) hypothetical protein 0.0063 0.0194 0.0194
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0012 0.0012
Brugia malayi diacylglycerol acyltransferase 0.0375 0.1464 0.1464
Brugia malayi Heterochromatin protein 1 0.0072 0.0231 0.0231
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.008 0.0264 0.0263
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0063 0.0194 0.0194
Echinococcus multilocularis zinc finger protein 0.0022 0.0026 0.0026
Echinococcus multilocularis leucyl tRNA synthetase 0.0023 0.0033 0.0033
Echinococcus granulosus geminin 0.0174 0.0647 0.0647
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0012 0.0012
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.1595 0.1595
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0147 0.0913
Echinococcus granulosus alpha 13 mannosyl glycoprotein 0.0106 0.037 0.0369
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0012 0.0012
Echinococcus multilocularis geminin 0.0174 0.0647 0.0647
Mycobacterium ulcerans leucyl-tRNA synthetase 0.0023 0.0033 0.043
Mycobacterium tuberculosis Probable lipase LipE 0.008 0.0264 0.1242
Schistosoma mansoni cpg binding protein 0.0032 0.0069 0.0069
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0015 0.0059
Echinococcus multilocularis thioredoxin glutathione reductase 0.0055 0.016 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.008 0.0264 0.1188
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0012 0.0012
Echinococcus multilocularis zinc finger transcription factor gli2 0.0349 0.1359 0.1358
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0012 0.0012
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0015 0.0059
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0039 0.0038
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0063 0.0194 0.0194
Wolbachia endosymbiont of Brugia malayi leucyl-tRNA synthetase 0.0023 0.0033 0.106
Trypanosoma brucei diacylglycerol acyltransferase, putative 0.0558 0.2207 1
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0147 0.0658
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0012 0.0012
Brugia malayi steroid hormone receptor 0.0018 0.0012 0.0012
Trypanosoma cruzi glycerol uptake protein, putative 0.0063 0.0194 0.0873
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.2473 1 1
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0012 0.0012
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0015 0.0015
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.008 0.0264 0.5849
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Echinococcus multilocularis cpg binding protein 0.0032 0.0069 0.0068
Mycobacterium tuberculosis Conserved protein 0.008 0.0264 0.1242
Brugia malayi PHD-finger family protein 0.0027 0.0049 0.0048
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0558 0.2207 1
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0015 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0012 0.0012
Brugia malayi beta-lactamase family protein 0.008 0.0264 0.0263
Brugia malayi hypothetical protein 0.0122 0.0434 0.0434
Brugia malayi protein ZK524.3 0.0023 0.0033 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0079 0.0258 0.0258
Schistosoma mansoni hypothetical protein 0.0063 0.0194 0.0194
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0012 0.0012
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0031 0.0031
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0125 0.0444 0.2142
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0012 0.0012
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0063 0.0194 0.0194
Trypanosoma brucei glycerol uptake protein, putative 0.0063 0.0194 0.0873
Mycobacterium tuberculosis Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) 0.0061 0.0187 0.086
Mycobacterium tuberculosis Probable lipase LipD 0.008 0.0264 0.1242
Trypanosoma cruzi methionyl-tRNA synthetase, putative 0.0061 0.0187 0.0841
Leishmania major glycerol uptake protein, putative 0.0063 0.0194 0.0873
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0009 0.0009
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0024 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0012 0.0012
Brugia malayi Bromodomain containing protein 0.0039 0.0098 0.0098
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0012 0.0012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0242 0.0924 0.0924
Brugia malayi methionyl-tRNA synthetase 0.0061 0.0187 0.0187
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0375 0.1464 0.1464
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.0264 0.1333
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0827 0.4321
Onchocerca volvulus 0.008 0.0264 0.1146
Trypanosoma brucei methionyl-tRNA synthetase, putative 0.0061 0.0187 0.0841
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0827 0.4321
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.0023 0.0033 0.0033
Mycobacterium tuberculosis Probable dehydrogenase 0.0125 0.0444 0.2142
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0012 0.0012
Onchocerca volvulus 0.008 0.0264 0.1146
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0264 0.1333
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0024 0.0548
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0012 0.0012
Mycobacterium tuberculosis Probable reductase 0.0125 0.0444 0.2142
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0375 0.1464 1
Leishmania major methionyl-tRNA synthetase, putative 0.0061 0.0187 0.0841
Brugia malayi MBOAT family protein 0.0063 0.0194 0.0194
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0375 0.1464 0.6611
Echinococcus granulosus thioredoxin glutathione reductase 0.0055 0.016 0.0159
Leishmania major trypanothione reductase 0.0055 0.016 0.0717
Loa Loa (eye worm) hypothetical protein 0.0063 0.0194 0.0194
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0063 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.008 0.0264 0.0263
Trichomonas vaginalis set domain proteins, putative 0.0482 0.1899 1
Leishmania major diacylglycerol acyltransferase, putative 0.0124 0.044 0.1989
Trypanosoma cruzi glycerol uptake protein, putative 0.0063 0.0194 0.0873
Loa Loa (eye worm) hypothetical protein 0.0079 0.0258 0.0258
Echinococcus granulosus o acyltransferase membrane bound domain 0.0063 0.0194 0.0194
Echinococcus granulosus methionine tRNA synthetase 0.0061 0.0187 0.0187
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0067 0.0067
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.0012 0.0012
Echinococcus multilocularis alpha 1,3 mannosyl glycoprotein 0.0106 0.037 0.0369
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0063 0.0194 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0012 0.0012
Leishmania major hypothetical protein, unknown function,protein, unknown function 0.0124 0.044 0.1989
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0231 0.0231
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0063 0.0194 0.0194
Brugia malayi CXXC zinc finger family protein 0.0029 0.0054 0.0054
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0012 0.0012
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0012 0.0011
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0024 0.0063
Brugia malayi Glycosylation related protein 12, isoform 0.0036 0.0084 0.0084
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.008 0.0264 0.1242
Echinococcus multilocularis methionine tRNA synthetase 0.0061 0.0187 0.0187
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0015 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0102 0.0478
Trypanosoma brucei hypothetical protein, conserved 0.008 0.0264 0.1188
Leishmania major glycerol uptake protein, putative 0.0063 0.0194 0.0873
Giardia lamblia Leucyl-tRNA synthetase 0.0023 0.0033 0.106
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0063 0.0194 0.0194
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0147 0.0603
Mycobacterium tuberculosis Probable esterase LipL 0.008 0.0264 0.1242
Entamoeba histolytica hypothetical protein 0.0063 0.0194 0.4456
Loa Loa (eye worm) hhat protein 0.0063 0.0194 0.0194
Leishmania major hypothetical protein, conserved 0.0051 0.0147 0.0658
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0124 0.044 0.1989
Brugia malayi beta-lactamase 0.008 0.0264 0.0263
Trypanosoma brucei glycerol uptake protein, putative 0.0063 0.0194 0.0873
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0231 0.1162
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0012 0.0012
Schistosoma mansoni zinc finger protein 0.0063 0.0194 0.0194
Brugia malayi hypothetical protein 0.0033 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.008 0.0264 0.0263
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0827 0.4321
Loa Loa (eye worm) hypothetical protein 0.0046 0.0123 0.0122
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.008 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0084
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0024 0.0024
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0024 0.0065
Schistosoma mansoni methionine-tRNA synthetase 0.0023 0.0033 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0194 0.0965
Trypanosoma brucei diacylglycerol acyltransferase, putative 0.0124 0.044 0.1989
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0242 0.0924 0.0924
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0147 0.0658
Leishmania major diacylglycerol acyltransferase, putative 0.0124 0.044 0.1989
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0012 0.0012
Trypanosoma cruzi GUP1, putative 0.0063 0.0194 0.0873
Brugia malayi hypothetical protein 0.0051 0.0147 0.0147
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0147 0.0913
Mycobacterium ulcerans beta-lactamase 0.008 0.0264 0.5849
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0375 0.1464 0.6611
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0124 0.044 0.1989
Schistosoma mansoni diacylglycerol O-acyltransferase 0.0124 0.044 0.044
Loa Loa (eye worm) hypothetical protein 0.0106 0.037 0.0369
Onchocerca volvulus 0.0272 0.1044 0.47
Leishmania major hypothetical protein, conserved 0.008 0.0264 0.1188
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0063 0.0194 0.0194
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0115 0.0544
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0124 0.044 0.1989
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0039 0.0039
Schistosoma mansoni diacylglycerol O-acyltransferase 0.0124 0.044 0.044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0012 0.0012
Plasmodium falciparum methionine--tRNA ligase 0.0061 0.0187 0.1191
Plasmodium vivax methionine--tRNA ligase, putative 0.0061 0.0187 0.1191
Brugia malayi beta-lactamase family protein 0.008 0.0264 0.0263
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0024 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0219 0.0827 0.4321
Loa Loa (eye worm) hypothetical protein 0.0312 0.1207 0.1207
Echinococcus granulosus cpg binding protein 0.0032 0.0069 0.0068
Leishmania major diacylglycerol acyltransferase, putative 0.0558 0.2207 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0073 0.0235 0.0235
Schistosoma mansoni chromobox protein 0.0072 0.0231 0.0231
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0024 0.0222
Plasmodium vivax thioredoxin reductase, putative 0.0055 0.016 0.1001
Brugia malayi nuclear hormone receptor 0.0018 0.0012 0.0012
Mycobacterium tuberculosis Conserved protein 0.008 0.0264 0.1242
Schistosoma mansoni leucyl-tRNA synthetase 0.0023 0.0033 0.0033
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0375 0.1464 0.1464
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0015 0.0013
Entamoeba histolytica vacuolar protein sorting 26 0.0063 0.0194 0.4456
Entamoeba histolytica hypothetical protein 0.0115 0.0406 1
Onchocerca volvulus 0.0038 0.0092 0.0364
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0015 0.0059
Echinococcus granulosus beta LACTamase domain containing family member 0.008 0.0264 0.0263
Trichomonas vaginalis D-aminoacylase, putative 0.008 0.0264 0.1333
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0015 0.0059
Echinococcus granulosus GPCR family 2 0.0032 0.0067 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0015 0.0059
Schistosoma mansoni hypothetical protein 0.0174 0.0647 0.0647
Trichomonas vaginalis penicillin-binding protein, putative 0.008 0.0264 0.1333
Entamoeba histolytica hypothetical protein 0.0115 0.0406 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0138 0.0501 0.2424
Loa Loa (eye worm) hypothetical protein 0.0073 0.0234 0.0233
Schistosoma mansoni hypothetical protein 0.0021 0.0024 0.0024
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0012 0.0012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0024 0.0101
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0088 0.0088
Schistosoma mansoni ap endonuclease 0.0021 0.0024 0.0024
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.0023 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.008 0.0264 0.0263
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0558 0.2207 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0115 0.0468
Schistosoma mansoni hypothetical protein 0.0032 0.0067 0.0067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0015 0.0059
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0063 0.0194 0.4456
Brugia malayi MBOAT family protein 0.0063 0.0194 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0194 0.0965
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Brugia malayi diacylglycerol acyltransferase family protein 0.0558 0.2207 0.2207
Trypanosoma cruzi diacylglycerol acyltransferase, putative 0.0124 0.044 0.1989
Onchocerca volvulus 0.0032 0.0067 0.0249
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0012 0.0012
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0067 0.0067
Echinococcus granulosus chromobox protein 1 0.0072 0.0231 0.0231
Trichomonas vaginalis methionine-tRNA synthetase, putative 0.0061 0.0187 0.0928
Mycobacterium ulcerans hypothetical protein 0.008 0.0264 0.5849
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0024 0.0527
Mycobacterium ulcerans methionyl-tRNA synthetase 0.0061 0.0187 0.4053
Chlamydia trachomatis methionine--tRNA ligase 0.0023 0.0033 1
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0015 0.0059
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0012 0.0012
Echinococcus granulosus zinc finger transcription factor gli2 0.0349 0.1359 0.1358
Brugia malayi MBOAT family protein 0.0063 0.0194 0.0194
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0024 0.0024
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0012 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0079 0.0258 0.0258
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0079 0.0258 0.0258

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0007 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.6586 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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