Detailed information for compound 1356461

Basic information

Technical information
  • TDR Targets ID: 1356461
  • Name: 4-methyl-5-naphthalen-1-yl-2H-1,2,4-triazole- 3-thione
  • MW: 241.312 | Formula: C13H11N3S
  • H donors: 0 H acceptors: 2 LogP: 2.82 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cn1c(S)nnc1c1cccc2c1cccc2
  • InChi: 1S/C13H11N3S/c1-16-12(14-15-13(16)17)11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,15,17)
  • InChiKey: MGUHLOGXTXQTPS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-methyl-5-(1-naphthyl)-2H-1,2,4-triazole-3-thione
  • ZINC00309478
  • ST5437757
  • 4-methyl-5-(1-naphthyl)-4H-1,2,4-triazole-3-thiol
  • MLS000677216
  • SMR000271046

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Mus musculus transient receptor potential cation channel, subfamily C, member 4 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus TRP transient receptor potential channel Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus granulosus transient receptor potential gamma protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis transient receptor potential gamma protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K05328 transient receptor potential cation channel, subfamily C,, putative Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus granulosus transient receptor potential ion channel A Get druggable targets OG5_128782 All targets in OG5_128782
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni transient receptor potential channel 4 Get druggable targets OG5_128782 All targets in OG5_128782
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Short transient receptor potential channel 5, putative Get druggable targets OG5_128782 All targets in OG5_128782
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni transient receptor potential channel Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum Transient receptor potential-gamma protein, putative Get druggable targets OG5_128782 All targets in OG5_128782
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum ko:K05328 transient receptor potential cation channel, subfamily C,, putative Get druggable targets OG5_128782 All targets in OG5_128782
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum Short transient receptor potential channel 5, putative Get druggable targets OG5_128782 All targets in OG5_128782
Brugia malayi Transient-receptor-potential like protein Get druggable targets OG5_128782 All targets in OG5_128782
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis transient receptor potential ion channel A Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis TRP (transient receptor potential) channel Get druggable targets OG5_128782 All targets in OG5_128782
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128782 All targets in OG5_128782
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Echinococcus multilocularis short transient receptor potential channel 6 transient receptor potential cation channel, subfamily C, member 4 890 aa 799 aa 31.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.1009 0.1397
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0082 0.0076 0.0092
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0081 0.0075 0.0103
Echinococcus multilocularis Glutaredoxin protein 5 0.0253 0.0831 0.1151
Trypanosoma cruzi casein kinase II, putative 0.0175 0.0486 0.2181
Echinococcus multilocularis RNA directed DNA polymerase 0.0081 0.0075 0.0103
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0338 0.166
Plasmodium vivax glycogen synthase kinase 3, putative 0.0279 0.0947 0.828
Schistosoma mansoni septate junction protein 0.0077 0.0056 0.011
Onchocerca volvulus 0.0237 0.0761 0.1484
Leishmania major protein kinase, putative 0.0322 0.1134 0.5426
Schistosoma mansoni nephrin 0.0082 0.0078 0.0153
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0301 0.1044 0.5031
Schistosoma mansoni tyrosine kinase 0.0794 0.3214 0.6316
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Echinococcus granulosus N chimaerin 0.013 0.0292 0.0333
Schistosoma mansoni protein kinase C mu 0.007 0.0026 0.0051
Echinococcus granulosus Protein kinase C brain isozyme 0.0417 0.1552 0.1774
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0115 0.0222 0.0835
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0083 0.0085 0.0118
Entamoeba histolytica protein kinase , putative 0.0322 0.1134 0.556
Giardia lamblia Kinase, CAMK CAMKL 0.0083 0.0084 0.0419
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0281 0.0953 0.1089
Loa Loa (eye worm) hypothetical protein 0.0081 0.0075 0.0075
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0279 0.0947 0.0947
Loa Loa (eye worm) hypothetical protein 0.0067 0.0011 0.0011
Brugia malayi Protein kinase domain containing protein 0.0125 0.0266 0.0266
Echinococcus granulosus serine:threonine protein kinase N2 0.0263 0.0876 0.1001
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0136 0.0318 0.0318
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.0056 0.0056
Echinococcus granulosus neuroglian 0.02 0.0599 0.0685
Entamoeba histolytica hypothetical protein 0.007 0.0026 0.0127
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.007 0.0026 0.0026
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0083 0.0085 0.0097
Entamoeba histolytica cell division protein kinase 2, putative 0.0213 0.0654 0.3209
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0253 0.0831 0.1151
Leishmania major casein kinase, putative 0.0115 0.0222 0.0711
Schistosoma mansoni ste20-related kinase 0.039 0.1432 0.2814
Echinococcus granulosus transient receptor potential gamma protein 0.0117 0.0233 0.0267
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2336 1 1
Echinococcus granulosus Glutaredoxin protein 5 0.0253 0.0831 0.095
Schistosoma mansoni tyrosine kinase 0.0293 0.1009 0.1983
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0222 0.0436
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0281 0.0953 0.1318
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0141 0.0338 0.0338
Toxoplasma gondii CMGC kinase, CK2 family 0.0175 0.0486 0.2343
Loa Loa (eye worm) raf kinase 0.007 0.0026 0.0026
Echinococcus granulosus casein kinase I delta 0.0115 0.0222 0.0254
Schistosoma mansoni tyrosine kinase 0.073 0.2931 0.5761
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0115 0.0222 0.0222
Brugia malayi Protein kinase domain containing protein 0.0888 0.3624 0.3624
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0136 0.0318 0.0318
Schistosoma mansoni protein kinase 0.0175 0.0486 0.0955
Trichomonas vaginalis CMGC family protein kinase 0.0213 0.0654 0.3209
Entamoeba histolytica protein kinase, putative 0.0146 0.0359 0.176
Onchocerca volvulus 0.0125 0.0266 0.0519
Trypanosoma cruzi p21-activated kinase 3, putative 0.0082 0.0076 0.0092
Echinococcus multilocularis casein kinase ii subunit alpha 0.0175 0.0486 0.0673
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0364 0.132 0.132
Onchocerca volvulus 0.0077 0.0058 0.0114
Entamoeba histolytica protein kinase, putative 0.0113 0.0213 0.1045
Loa Loa (eye worm) TK/EGFR protein kinase 0.122 0.5088 0.5088
Echinococcus multilocularis protein kinase shaggy 0.0279 0.0947 0.131
Echinococcus granulosus tyrosine protein kinase HCK 0.0184 0.0528 0.0604
Brugia malayi Protein kinase domain containing protein 0.0203 0.0612 0.0612
Leishmania major protein kinase A catalytic subunit isoform 2 0.0119 0.0242 0.0813
Echinococcus granulosus hemicentin 1 0.0077 0.0056 0.0064
Schistosoma mansoni serine/threonine kinase 0.0162 0.0432 0.0848
Echinococcus granulosus mitogen activated protein kinase 14 0.0295 0.1017 0.1163
Schistosoma mansoni transient receptor potential channel 0.0117 0.0233 0.0459
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0328 0.1163 0.1329
Echinococcus multilocularis cyclin dependent kinase 0.0213 0.0654 0.0906
Entamoeba histolytica tyrosin kinase, putative 0.0071 0.0029 0.014
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0119 0.0242 0.0804
Echinococcus granulosus c src tyrosine kinase 0.0173 0.0481 0.055
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0242 0.0475
Echinococcus multilocularis nervana 2 0.0253 0.0831 0.1151
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0293 0.1009 0.1397
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0279 0.0947 0.1082
Onchocerca volvulus 0.0131 0.0294 0.0574
Trichomonas vaginalis AGC family protein kinase 0.0322 0.1134 0.556
Loa Loa (eye worm) hypothetical protein 0.0241 0.0777 0.0777
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0083 0.0084 0.0117
Brugia malayi Protein kinase domain containing protein 0.0162 0.0432 0.0432
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0322 0.1134 0.556
Brugia malayi phosphoinositide-dependent protein kinase I 0.0136 0.0318 0.0318
Brugia malayi Immunoglobulin I-set domain containing protein 0.1396 0.5863 0.5863
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0077 0.0056 0.0078
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0486 0.2383
Entamoeba histolytica protein kinase, putative 0.0263 0.0876 0.4295
Echinococcus multilocularis unc 13 (munc13) 0.0073 0.0037 0.0051
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0523 0.2018 0.2307
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0318 0.156
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0364 0.132 0.1828
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0082 0.0078 0.0089
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0064 0.0000058547 0.000006692
Loa Loa (eye worm) hypothetical protein 0.007 0.0026 0.0026
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0213 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0167 0.0453 0.0453
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0083 0.0085 0.0118
Trichomonas vaginalis STE family protein kinase 0.0146 0.0359 0.176
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0115 0.0222 0.0308
Echinococcus granulosus roundabout 2 0.0082 0.0078 0.0089
Trypanosoma cruzi casein kinase, putative 0.0115 0.0222 0.0835
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.0056 0.0056
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0119 0.0242 0.0804
Echinococcus multilocularis Diacylglycerol kinase theta 0.007 0.0026 0.0036
Loa Loa (eye worm) hypothetical protein 0.0074 0.0042 0.0042
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0141 0.0338 0.1592
Echinococcus multilocularis ephrin type A receptor 4 A 0.0195 0.0577 0.0798
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0794 0.3214 0.3673
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.1195 0.2349
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.1392 0.2736
Entamoeba histolytica protein kinase, putative 0.0279 0.0947 0.4642
Echinococcus granulosus roundabout 2 0.0246 0.0799 0.0913
Brugia malayi Protein kinase domain containing protein 0.0125 0.0266 0.0266
Trichomonas vaginalis CAMK family protein kinase 0.0523 0.2018 0.9898
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0511 0.1964 0.1964
Schistosoma mansoni protein kinase 0.0083 0.0085 0.0167
Entamoeba histolytica protein kinase, putative 0.0528 0.2039 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0301 0.1044 0.5122
Echinococcus multilocularis nervana 2 0.0253 0.0831 0.1151
Echinococcus granulosus tyrosine protein kinase ABL1 0.0549 0.2134 0.2439
Loa Loa (eye worm) TK/ROR protein kinase 0.0101 0.0161 0.0161
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0293 0.1009 0.1397
Brugia malayi Immunoglobulin I-set domain containing protein 0.0079 0.0064 0.0064
Brugia malayi Casein kinase II, alpha chain 0.0175 0.0486 0.0486
Trypanosoma cruzi cdc2-related kinase 3 0.0213 0.0654 0.304
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0486 0.2383
Schistosoma mansoni serine/threonine protein kinase 0.0776 0.3134 0.616
Leishmania major protein kinase, putative 0.0083 0.0085 0.0002
Plasmodium falciparum calcium-dependent protein kinase 4 0.0083 0.0085 0.0004
Onchocerca volvulus 0.0125 0.0266 0.0519
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0435 0.1633 0.1867
Giardia lamblia Kinase, CMGC GSK 0.0279 0.0947 0.469
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0125 0.0266 0.1304
Echinococcus multilocularis serine:threonine protein kinase 38 0.0263 0.0876 0.1212
Giardia lamblia Kinase, AGC PKA 0.029 0.0995 0.4929
Onchocerca volvulus 0.0125 0.0266 0.0519
Loa Loa (eye worm) AGC/PKN protein kinase 0.0263 0.0876 0.0876
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0432 0.0848
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0119 0.0242 0.0804
Loa Loa (eye worm) hypothetical protein 0.0169 0.046 0.046
Loa Loa (eye worm) RasGEF domain-containing protein 0.007 0.0026 0.0026
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0059 0.0081
Loa Loa (eye worm) TK/EPH protein kinase 0.0231 0.0735 0.0735
Brugia malayi Immunoglobulin I-set domain containing protein 0.0082 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.007 0.0026 0.0026
Echinococcus granulosus neuroglian 0.0082 0.0078 0.0089
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0289 0.0991 0.0991
Loa Loa (eye worm) hypothetical protein 0.0073 0.0037 0.0037
Echinococcus multilocularis cyclin dependent kinase 1 0.0213 0.0654 0.0906
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0222 0.0307
Brugia malayi Protein kinase c protein 2 0.0191 0.0558 0.0558
Echinococcus multilocularis neuroglian 0.0082 0.0078 0.0108
Toxoplasma gondii AGC kinase 0.0119 0.0242 0.1099
Entamoeba histolytica serine/threonine protein kinase, putative 0.0523 0.2018 0.9898
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0432 0.0848
Schistosoma mansoni protein kinase 0.0083 0.0085 0.0167
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0119 0.0242 0.0935
Entamoeba histolytica protein kinase domain containing protein 0.0071 0.0029 0.014
Brugia malayi serine/threonine-protein kinase 6 0.0322 0.1134 0.1134
Entamoeba histolytica protein kinase, putative 0.0098 0.0147 0.0721
Schistosoma mansoni hypothetical protein 0.0125 0.0268 0.0527
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0101 0.0164 0.0405
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0486 0.2383
Schistosoma mansoni serine/threonine protein kinase 0.0435 0.1633 0.321
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0083 0.0085 0.0085
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0281 0.0953 0.0953
Schistosoma mansoni growth factor receptor-bound protein 0.0109 0.0198 0.039
Onchocerca volvulus 0.0115 0.0222 0.0433
Schistosoma mansoni protein kinase 0.042 0.1564 0.3073
Loa Loa (eye worm) hypothetical protein 0.0109 0.0198 0.0198
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0042 0.0082
Trypanosoma cruzi cdc2-related kinase 1 0.0213 0.0654 0.304
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0115 0.0222 0.0254
Echinococcus multilocularis epidermal growth factor receptor 0.122 0.5088 0.7043
Echinococcus granulosus rho-associated protein kinase 1 0.0776 0.3134 0.3582
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Echinococcus granulosus mitogen activated protein kinase 0.0141 0.0338 0.0387
Trichomonas vaginalis STE family protein kinase 0.0146 0.0359 0.176
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0295 0.1017 0.4893
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0263 0.0876 0.1212
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0141 0.0338 0.1428
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0722 0.3543
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.013 0.0292 0.0573
Loa Loa (eye worm) hypothetical protein 0.0077 0.0056 0.0056
Echinococcus multilocularis N chimaerin 0.013 0.0292 0.0404
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.0654 0.1286
Giardia lamblia Kinase, STE STE20 0.0146 0.0359 0.1778
Echinococcus multilocularis myosin iiia 0.0143 0.0347 0.048
Loa Loa (eye worm) hypothetical protein 0.0169 0.046 0.046
Onchocerca volvulus 0.0079 0.0064 0.0124
Brugia malayi P38 map kinase family protein 2 0.0295 0.1017 0.1017
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0213 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0119 0.0242 0.0242
Brugia malayi STE20-like kinase MST 0.0495 0.1897 0.1897
Echinococcus granulosus titin 0.0079 0.0064 0.0073
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.022 0.0685 0.3106
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0082 0.0076 0.0076
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0222 0.0307
Brugia malayi hypothetical protein 0.0169 0.046 0.046
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0295 0.1017 0.4824
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0225 0.0311
Entamoeba histolytica protein kinase, putative 0.0115 0.0222 0.109
Plasmodium falciparum calcium-dependent protein kinase 1 0.0083 0.0085 0.0004
Entamoeba histolytica protein kinase, putative 0.0322 0.1134 0.556
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0073 0.0037 0.0042
Entamoeba histolytica protein kinase, putative 0.0086 0.0096 0.0472
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.022 0.0685 0.0685
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.029 0.0995 0.8724
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.013 0.0292 0.0573
Echinococcus multilocularis mitogen activated protein kinase 0.0141 0.0338 0.0468
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0226 0.0712 0.3493
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0213 0.0654 0.32
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.0056 0.0056
Echinococcus multilocularis hemicentin 1 0.0077 0.0056 0.0078
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.029 0.0995 0.1377
Schistosoma mansoni kinase 0.0561 0.2184 0.4293
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0322 0.1134 0.556
Echinococcus granulosus raf serine:threonine protein kinase 0.0134 0.0308 0.0352
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.013 0.0292 0.0404
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0338 0.166
Schistosoma mansoni diacylglycerol kinase theta 0.007 0.0026 0.0051
Brugia malayi Protein kinase domain containing protein 0.0358 0.1293 0.1293
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0083 0.0085 0.0097
Trichomonas vaginalis set domain proteins, putative 0.0286 0.0976 0.4789
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0417 0.1552 0.2149
Echinococcus multilocularis fibroblast growth factor receptor 4 0.047 0.1785 0.2471
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Schistosoma mansoni tyrosine kinase 0.073 0.2931 0.5761
Trichomonas vaginalis CMGC family protein kinase 0.0213 0.0654 0.3209
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Echinococcus multilocularis cyclin dependent kinase 1 0.0213 0.0654 0.0906
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0722 0.3543
Loa Loa (eye worm) hypothetical protein 0.0169 0.046 0.046
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0073 0.0037 0.0051
Echinococcus granulosus aurora kinase A 0.0322 0.1134 0.1296
Echinococcus granulosus protein kinase shaggy 0.0279 0.0947 0.1082
Echinococcus granulosus NCK adaptor protein 0.0109 0.0198 0.0227
Loa Loa (eye worm) hypothetical protein 0.0176 0.0491 0.0491
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0435 0.1633 0.2261
Loa Loa (eye worm) hypothetical protein 0.0077 0.0056 0.0056
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0511 0.1964 0.2719
Schistosoma mansoni protein kinase 0.0115 0.0222 0.0436
Brugia malayi Peroxidasin 0.0077 0.0058 0.0058
Echinococcus granulosus insulin receptor 0.0888 0.3624 0.4143
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0293 0.1009 0.1397
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.0824 0.0824
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0281 0.0953 0.0953
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0082 0.0076 0.0076
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0229 0.0723 0.0827
Brugia malayi P21-Rho-binding domain containing protein 0.0064 0.0000058547 0.0000058547
Loa Loa (eye worm) hypothetical protein 0.0125 0.0268 0.0268
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0516 0.1989 0.1989
Brugia malayi P21-Rho-binding domain containing protein 0.0064 0.0000058547 0.0000058547
Schistosoma mansoni cell adhesion molecule 0.0082 0.0078 0.0153
Echinococcus granulosus tyrosine protein kinase Srms 0.0125 0.0266 0.0304
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0213 0.0654 0.0748
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1396 0.5863 0.5863
Schistosoma mansoni serine/threonine protein kinase 0.0511 0.1964 0.386
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0082 0.0078 0.0108
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0082 0.0076 0.0375
Trichomonas vaginalis AGC family protein kinase 0.0528 0.2039 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0078 0.0059 0.0081
Giardia lamblia Aurora kinase 0.0322 0.1134 0.5618
Echinococcus granulosus Diacylglycerol kinase theta 0.007 0.0026 0.0029
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0263 0.0876 0.1001
Echinococcus granulosus titin 0.0079 0.0064 0.0073
Brugia malayi Tyrosine-protein kinase abl-1 0.0262 0.0871 0.0871
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0083 0.0084 0.036
Giardia lamblia Kinase, CMGC CDK 0.0213 0.0654 0.3241
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0222 0.1089
Trichomonas vaginalis AGC family protein kinase 0.0322 0.1134 0.556
Loa Loa (eye worm) hypothetical protein 0.0077 0.0056 0.0056
Schistosoma mansoni titin 0.0079 0.0064 0.0125
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.1009 0.1397
Brugia malayi diacylglycerol kinase 0.007 0.0026 0.0026
Brugia malayi Protein kinase domain containing protein 0.0364 0.132 0.132
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0274 0.0924 0.0924
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0953 0.1872
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0162 0.0432 0.0432
Plasmodium falciparum casein kinase 1 0.0115 0.0222 0.1311
Trypanosoma brucei protein kinase, putative 0.0279 0.0947 0.4411
Schistosoma mansoni protein kinase 0.0146 0.0359 0.0705
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0523 0.2018 1
Brugia malayi casein kinase 1, delta 0.0115 0.0222 0.0222
Giardia lamblia Kinase, NEK 0.0248 0.081 0.4015
Giardia lamblia Kinase, CMGC CDK 0.0213 0.0654 0.3241
Brugia malayi MAP kinase sur-1 0.0141 0.0338 0.0338
Trichomonas vaginalis CAMK family protein kinase 0.0523 0.2018 0.9898
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Brugia malayi Protein kinase domain containing protein 0.0136 0.0318 0.0318
Onchocerca volvulus 0.0284 0.0967 0.1887
Echinococcus multilocularis neuroglian 0.02 0.0599 0.0829
Entamoeba histolytica diacylglycerol kinase, putative 0.007 0.0026 0.0127
Trypanosoma cruzi cdc2-related kinase 1 0.0213 0.0654 0.304
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0225 0.0257
Echinococcus granulosus tyrosine protein kinase Blk 0.0245 0.0794 0.0908
Echinococcus granulosus NDR protein kinase 0.0263 0.0876 0.1001
Trypanosoma brucei protein kinase, putative 0.0101 0.0164 0.0405
Brugia malayi serine/threonine-protein kinase plk-2 0.0523 0.2018 0.2018
Echinococcus multilocularis protein kinase c eta type 0.007 0.0026 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0876 0.1721
Brugia malayi Protein kinase domain containing protein 0.0263 0.0876 0.0876
Brugia malayi Protein kinase domain containing protein 0.0213 0.0654 0.0654
Schistosoma mansoni protein kinase 0.0083 0.0085 0.0167
Echinococcus granulosus serine threonine protein kinase nrc 0.029 0.0995 0.1137
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0876 0.1721
Echinococcus multilocularis Immunoglobulin 0.0164 0.0438 0.0607
Brugia malayi SH2 domain containing protein 0.0125 0.0266 0.0266
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0445 0.1674 0.1674
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0523 0.2018 0.2794
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0143 0.0347 0.1471
Trichomonas vaginalis CMGC family protein kinase 0.0279 0.0947 0.4642
Schistosoma mansoni serine/threonine protein kinase 0.0417 0.1552 0.3051
Echinococcus granulosus activin receptor type 0.0101 0.0164 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0222 0.0437
Trypanosoma cruzi polo-like protein kinase, putative 0.0523 0.2018 1
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0077 0.0056 0.011
Schistosoma mansoni ephrin receptor 0.0069 0.0022 0.0043
Echinococcus granulosus PAK box P21 Rho binding 0.0064 0.0000058547 0.000006692
Loa Loa (eye worm) TK/ABL protein kinase 0.0549 0.2134 0.2134
Onchocerca volvulus 0.0776 0.3134 0.6114
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0446 0.1682 0.1923
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0083 0.0085 0.0085
Schistosoma mansoni tyrosine kinase 0.0293 0.1009 0.1983
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0328 0.1163 0.1609
Echinococcus multilocularis epidermal growth factor receptor 0.0794 0.3214 0.4448
Entamoeba histolytica hypothetical protein 0.0065 0.0002 0.001
Plasmodium vivax protein kinase Crk2 0.0213 0.0654 0.5594
Onchocerca volvulus 0.0073 0.0037 0.0073
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0077 0.0056 0.011
Echinococcus multilocularis mitogen activated protein kinase 3 0.0141 0.0338 0.0468
Echinococcus granulosus serine:threonine protein kinase 0.0203 0.0612 0.07
Echinococcus granulosus protein kinase c epsilon type 0.0336 0.1195 0.1366
Entamoeba histolytica p21-activated kinase 0.0157 0.0408 0.2003
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.1163 0.2285
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0119 0.0241 0.0241
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.022 0.0685 0.3198
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.029 0.0995 0.1137
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0109 0.0198 0.0198
Schistosoma mansoni tyrosine kinase 0.0888 0.3624 0.7123
Giardia lamblia Kinase, STE STE20 0.0143 0.0347 0.1718
Echinococcus multilocularis myotubularin protein 13 0.0081 0.0075 0.0104
Loa Loa (eye worm) AUR protein kinase 0.0322 0.1134 0.1134
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0083 0.0085 0.0097
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0141 0.0338 0.1428
Brugia malayi protein-tyrosine kinase 0.0245 0.0794 0.0794
Trypanosoma cruzi aurora B kinase, putative 0.0322 0.1134 0.5487
Echinococcus multilocularis casein kinase i 0.0115 0.0222 0.0307
Schistosoma mansoni serine/threonine protein kinase 0.0417 0.1552 0.3051
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0101 0.0161 0.0184
Plasmodium falciparum calcium-dependent protein kinase 5 0.0083 0.0085 0.0004
Brugia malayi Pre-SET motif family protein 0.0251 0.0824 0.0824
Trichomonas vaginalis STE family protein kinase 0.0143 0.0347 0.17
Echinococcus multilocularis serine:threonine protein kinase 0.0203 0.0612 0.0847
Echinococcus multilocularis PAK box P21 Rho binding 0.0101 0.0164 0.0226
Trypanosoma cruzi casein kinase, putative 0.0115 0.0222 0.0835
Echinococcus multilocularis aurora kinase A 0.0322 0.1134 0.1569
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0263 0.0876 0.1212
Toxoplasma gondii histone kinase SNF1, putative 0.0083 0.0084 0.0299
Schistosoma mansoni vesicular amine transporter 0.0168 0.0456 0.0895
Echinococcus granulosus epidermal growth factor receptor 0.122 0.5088 0.5816
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0213 0.0654 0.2946
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0723 0.1421
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0308 0.0606
Echinococcus multilocularis serine:threonine protein kinase 0.0203 0.0612 0.0847
Brugia malayi Ras association domain family 1 isoform A 0.007 0.0026 0.0026
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0263 0.0876 0.1001
Schistosoma mansoni nephrin 0.0205 0.0621 0.122
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0119 0.0242 0.0335
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.022 0.0685 0.3073
Echinococcus multilocularis mitogen activated protein kinase 11 0.0295 0.1017 0.1408
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.1009 0.1397
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0119 0.0242 0.0935
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Trichomonas vaginalis STE family protein kinase 0.0146 0.0359 0.176
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0119 0.0242 0.0276
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0293 0.1009 0.1397
Echinococcus multilocularis tyrosine protein kinase Srms 0.0245 0.0794 0.1099
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.013 0.0292 0.0333
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0486 0.2383
Brugia malayi diacylglycerol kinase 0.007 0.0026 0.0026
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0101 0.0164 0.0536
Plasmodium falciparum calcium-dependent protein kinase 2 0.0083 0.0085 0.0004
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.047 0.1785 0.2041
Echinococcus granulosus tyrosine protein kinase otk 0.0077 0.0056 0.0064
Schistosoma mansoni cell adhesion molecule 0.0077 0.0056 0.011
Echinococcus granulosus protein kinase C gamma type 0.0347 0.1244 0.1422
Brugia malayi Variant SH3 domain containing protein 0.0074 0.0044 0.0044
Onchocerca volvulus 0.1128 0.4682 0.9135
Brugia malayi Protein kinase domain containing protein 0.0125 0.0266 0.0266
Trypanosoma brucei polo-like protein kinase 0.0523 0.2018 0.9894
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.0654 0.1286
Loa Loa (eye worm) hypothetical protein 0.0237 0.0761 0.0761
Echinococcus granulosus transient receptor potential ion channel A 0.0113 0.0216 0.0247
Entamoeba histolytica protein kinase, putative 0.0184 0.0528 0.259
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0146 0.0359 0.0497
Trichomonas vaginalis AGC family protein kinase 0.0119 0.0242 0.1185
Brugia malayi Protein kinase domain containing protein 0.0528 0.2039 0.2039
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0279 0.0947 0.131
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.0056 0.0056
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0109 0.0198 0.039
Plasmodium falciparum casein kinase 2, alpha subunit 0.0175 0.0486 0.3826
Echinococcus multilocularis 0.0355 0.1282 0.1774
Entamoeba histolytica casein kinase 1, putative 0.0115 0.0222 0.1089
Giardia lamblia Kinase, CAMK CAMKL 0.0083 0.0084 0.0419
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0164 0.0438 0.0862
Loa Loa (eye worm) hypothetical protein 0.0164 0.0438 0.0438
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0119 0.0242 0.1099
Echinococcus granulosus mitogen activated protein kinase 3 0.0141 0.0338 0.0387
Trypanosoma cruzi polo-like protein kinase, putative 0.0523 0.2018 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.047 0.1785 0.2041
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0221 0.0688 0.3122
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0083 0.0084 0.0133
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0083 0.0085 0.0364
Echinococcus granulosus lachesin 0.0077 0.0056 0.0064
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0064 0.0000058547 0.0000081041
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.0947 0.4642
Loa Loa (eye worm) hypothetical protein 0.007 0.0026 0.0026
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0248 0.081 0.3995
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0064 0.0000058547 0.000006692
Loa Loa (eye worm) hypothetical protein 0.0077 0.0056 0.0056
Echinococcus multilocularis Rac GTPase activating protein 1 0.007 0.0026 0.0036
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0146 0.0359 0.0497
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0203 0.0612 0.0612
Trichomonas vaginalis AGC family protein kinase 0.0528 0.2039 1
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0065 0.0002 0.001
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0318 0.156
Schistosoma mansoni tyrosine kinase 0.073 0.2931 0.5761
Echinococcus granulosus casein kinase I delta 0.0115 0.0222 0.0254
Brugia malayi ephrin receptor 1 precursor 0.0126 0.0272 0.0272
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0245 0.0794 0.1099
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0082 0.0078 0.0108
Echinococcus multilocularis roundabout 2 0.0082 0.0078 0.0108
Brugia malayi Variant SH3 domain containing protein 0.0109 0.0198 0.0198
Brugia malayi Protein kinase domain containing protein 0.0351 0.1261 0.1261
Trichomonas vaginalis AGC family protein kinase 0.0528 0.2039 1
Echinococcus granulosus casein kinase I alpha 0.0115 0.0222 0.0254
Loa Loa (eye worm) hypothetical protein 0.0164 0.0438 0.0438
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0084 0.0166
Echinococcus multilocularis casein kinase I delta 0.0115 0.0222 0.0307
Schistosoma mansoni hypothetical protein 0.007 0.0026 0.0051
Echinococcus multilocularis rho associated protein kinase 0.0776 0.3134 0.4338
Echinococcus granulosus tyrosine protein kinase Src42A 0.018 0.0512 0.0585
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0141 0.0338 0.1428
Schistosoma mansoni roundabout 0.0077 0.0056 0.011
Echinococcus multilocularis twitchin 0.0074 0.0042 0.0058
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0119 0.0242 0.0276
Loa Loa (eye worm) hypothetical protein 0.0077 0.0058 0.0058
Entamoeba histolytica casein kinase, putative 0.0115 0.0222 0.1089
Echinococcus granulosus mitogen activated protein kinase 11 0.0295 0.1017 0.1163
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0279 0.0947 0.0947
Trichomonas vaginalis CMGC family protein kinase 0.0279 0.0947 0.4642
Schistosoma mansoni hypothetical protein 0.0125 0.0268 0.0527
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0101 0.0161 0.0223
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0085 0.0416
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.1009 0.1153
Entamoeba histolytica protein kinase, putative 0.022 0.0685 0.336
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0213 0.0654 0.0654
Echinococcus granulosus cyclin dependent kinase 5 0.0213 0.0654 0.0748
Schistosoma mansoni unc-13 (munc13) 0.0073 0.0037 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0338 0.166
Schistosoma mansoni tyrosine kinase 0.0173 0.0481 0.0945
Giardia lamblia Kinase, NEK 0.0248 0.081 0.4015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0169 0.046 0.046
Brugia malayi Fibronectin type III domain containing protein 0.0169 0.046 0.046
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0279 0.0947 0.4532
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0143 0.0347 0.1342
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0893 0.3646 0.4168
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0079 0.0064 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Loa Loa (eye worm) hypothetical protein 0.0167 0.0453 0.0453
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0295 0.1017 0.4773
Schistosoma mansoni tyrosine kinase 0.0128 0.0282 0.0555
Brugia malayi Hr1 repeat family protein 0.0263 0.0876 0.0876
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0328 0.1163 0.1329
Echinococcus multilocularis insulin receptor 0.0888 0.3624 0.5017
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0338 0.166
Echinococcus multilocularis casein kinase I alpha 0.0115 0.0222 0.0307
Entamoeba histolytica hypothetical protein 0.022 0.0685 0.336
Echinococcus multilocularis roundabout 2 0.0082 0.0078 0.0108
Brugia malayi Stress-activated protein kinase jnk-1 0.0511 0.1964 0.1964
Brugia malayi Immunoglobulin I-set domain containing protein 0.0506 0.1946 0.1946
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0222 0.1089
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0295 0.1017 0.4893
Loa Loa (eye worm) RhoGAP domain-containing protein 0.013 0.0292 0.0292
Schistosoma mansoni unc-13 (munc13) 0.0073 0.0037 0.0073
Schistosoma mansoni diacylglycerol kinase theta 0.007 0.0026 0.0051
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0274 0.0924 0.0924
Trichomonas vaginalis CK1 family protein kinase 0.0115 0.0222 0.1089
Trypanosoma cruzi rac serine-threonine kinase, putative 0.029 0.0995 0.4778
Echinococcus multilocularis tyrosine protein kinase Abl 0.0336 0.1195 0.1654
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0082 0.0078 0.0108
Schistosoma mansoni tyrosine kinase 0.0125 0.0266 0.0522
Schistosoma mansoni transient receptor potential channel 4 0.0117 0.0233 0.0459
Schistosoma mansoni tyrosine kinase 0.0794 0.3214 0.6316
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0143 0.0347 0.1471
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0146 0.0359 0.041
Trichomonas vaginalis CAMK family protein kinase 0.0523 0.2018 0.9898
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0121 0.0237
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.038 0.1392 0.1591
Entamoeba histolytica protein kinase, putative 0.0528 0.2039 1
Echinococcus granulosus tyrosine protein kinase Lyn 0.0331 0.1172 0.134
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0141 0.0338 0.1313
Trichomonas vaginalis AGC family protein kinase 0.0528 0.2039 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0119 0.0242 0.0935
Brugia malayi Sex muscle abnormal protein 5 0.0109 0.0198 0.0198
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0101 0.0164 0.0536
Loa Loa (eye worm) hypothetical protein 0.0183 0.0522 0.0522
Brugia malayi C1-like domain containing protein 0.0274 0.0924 0.0924
Brugia malayi Protein kinase domain containing protein 0.022 0.0685 0.0685
Onchocerca volvulus 0.0125 0.0266 0.0519
Trichomonas vaginalis AGC family protein kinase 0.0528 0.2039 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0141 0.0338 0.1313
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.1009 0.1153
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0364 0.132 0.1509
Giardia lamblia Kinase, CK1 Casein kinase 0.0115 0.0222 0.11
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0204 0.0616 0.0616
Echinococcus multilocularis c src tyrosine kinase 0.0173 0.0481 0.0666
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0119 0.0242 0.0335
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0364 0.132 0.132
Loa Loa (eye worm) hypothetical protein 0.0082 0.0078 0.0078
Giardia lamblia Kinase, CMGC GSK 0.0279 0.0947 0.469
Trypanosoma cruzi casein kinase, putative 0.0115 0.0222 0.0835
Loa Loa (eye worm) AGC/AKT protein kinase 0.0528 0.2039 0.2039
Echinococcus granulosus Immunoglobulin 0.0164 0.0438 0.0501
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0083 0.0085 0.0118
Brugia malayi RhoGEF domain containing protein 0.007 0.0026 0.0026
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0082 0.0078 0.0089
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0125 0.0266 0.0368
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0266 0.0889 0.123
Echinococcus multilocularis tyrosine protein kinase shark 0.0125 0.0266 0.0368
Plasmodium falciparum calcium-dependent protein kinase 3 0.0083 0.0085 0.0004
Entamoeba histolytica protein kinase, putative 0.0083 0.0085 0.0416
Entamoeba histolytica protein kinase domain containing protein 0.022 0.0685 0.336
Echinococcus multilocularis death associated protein kinase 1 0.1706 0.7224 1
Echinococcus granulosus contactin 0.0082 0.0078 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0213 0.0654 0.2946
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0074 0.0044 0.0044
Loa Loa (eye worm) TK protein kinase 0.0184 0.0528 0.0528
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0164 0.0438 0.0862
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0076 0.015
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Schistosoma mansoni vav2 0.0142 0.0341 0.0671
Loa Loa (eye worm) hypothetical protein 0.0081 0.0075 0.0075
Onchocerca volvulus 0.0739 0.297 0.5795
Plasmodium falciparum serine/threonine protein kinase, putative 0.0322 0.1134 1
Brugia malayi Temporarily assigned gene name protein 59 0.0264 0.0879 0.0879
Leishmania major protein kinase, putative 0.0143 0.0347 0.1356
Trichomonas vaginalis CAMK family protein kinase 0.0523 0.2018 0.9898
Brugia malayi p70 ribosomal S6 kinase beta 0.0516 0.1989 0.1989
Brugia malayi serine/threonine protein kinase 6 0.0322 0.1134 0.1134
Brugia malayi Variant SH3 domain containing protein 0.013 0.0292 0.0292
Echinococcus granulosus peroxidasin 0.0077 0.0058 0.0066
Brugia malayi putative serine/threonine kinase SADA gamma 0.0083 0.0084 0.0084
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0364 0.132 0.2576
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0322 0.1134 0.556
Brugia malayi protein kinase C II. 0.0336 0.1195 0.1195
Echinococcus granulosus dual specificity 0.022 0.0685 0.0783
Echinococcus multilocularis mitogen activated protein kinase 14 0.0295 0.1017 0.1408
Echinococcus granulosus serine:threonine kinase SAD 1 0.0083 0.0084 0.0097
Echinococcus granulosus c-Jun N-terminal kinases 0.0511 0.1964 0.2245
Loa Loa (eye worm) hypothetical protein 0.007 0.0026 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0274 0.0925 0.4538
Loa Loa (eye worm) hypothetical protein 0.0547 0.2126 0.2126
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.0056 0.0056
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0486 0.2383
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0121 0.025 0.025
Echinococcus multilocularis serine:threonine protein kinase N2 0.0263 0.0876 0.1212
Schistosoma mansoni rac gtpase activating protein 0.007 0.0026 0.0051
Trypanosoma brucei rac serine-threonine kinase, putative 0.0528 0.2039 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0083 0.0085 0.0364
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0115 0.0222 0.0308
Onchocerca volvulus 0.0279 0.0947 0.1847
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0083 0.0085 0.0364
Loa Loa (eye worm) hypothetical protein 0.0248 0.081 0.081
Loa Loa (eye worm) hypothetical protein 0.007 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0151 0.0383 0.0383
Schistosoma mansoni serine/threonine protein kinase 0.0322 0.1134 0.2228
Onchocerca volvulus 0.009 0.0114 0.0223
Onchocerca volvulus 0.0248 0.081 0.1581
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0175 0.0486 0.4048
Echinococcus granulosus epidermal growth factor receptor 0.0794 0.3214 0.3673
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0083 0.0084 0.0084
Echinococcus granulosus serine/threonine protein kinase 0.0301 0.1044 0.1194
Echinococcus granulosus casein kinase i 0.0115 0.0222 0.0254
Loa Loa (eye worm) variant SH3 domain-containing protein 0.007 0.0026 0.0026
Echinococcus multilocularis tyrosine kinase 0.0125 0.0266 0.0368
Entamoeba histolytica protein kinase, putative 0.0516 0.1989 0.9757
Onchocerca volvulus 0.0125 0.0266 0.0519
Brugia malayi intracellular kinase 0.0279 0.0947 0.0947
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.038 0.1392 0.1927
Echinococcus granulosus tyrosine protein kinase Src64B 0.0293 0.1009 0.1153
Brugia malayi Protein kinase domain containing protein 0.0381 0.1392 0.1392
Echinococcus multilocularis protein kinase c iota type 0.0503 0.1931 0.2672
Echinococcus multilocularis activin receptor type 0.0101 0.0164 0.0226
Echinococcus multilocularis protein kinase c epsilon type 0.0336 0.1195 0.1655
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0229 0.0723 0.1001
Echinococcus multilocularis tyrosine protein kinase Blk 0.0245 0.0794 0.1099
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0119 0.0242 0.0335
Trichomonas vaginalis STE family protein kinase 0.0101 0.0164 0.0802
Schistosoma mansoni serine/threonine protein kinase 0.0136 0.0318 0.0625
Entamoeba histolytica protein kinase domain containing protein 0.0101 0.0164 0.0802
Schistosoma mansoni protein kinase 0.0322 0.1134 0.2228
Echinococcus multilocularis casein kinase I delta 0.0115 0.0222 0.0307
Loa Loa (eye worm) hypothetical protein 0.0164 0.044 0.044
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0175 0.0486 0.0486
Entamoeba histolytica PH domain containing protein kinase, putative 0.013 0.0291 0.1428
Entamoeba histolytica protein kinase, putative 0.0136 0.0318 0.156
Trypanosoma brucei Casein kinase II 0.0175 0.0486 0.2054
Schistosoma mansoni tyrosine kinase 0.0398 0.1467 0.2883
Brugia malayi Immunoglobulin I-set domain containing protein 0.0077 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0109 0.0195 0.0195
Echinococcus granulosus cyclin dependent kinase 1 0.0213 0.0654 0.0748
Brugia malayi hypothetical protein 0.0125 0.0266 0.0266
Echinococcus granulosus twitchin 0.0238 0.0763 0.0872
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0125 0.0266 0.0304
Trypanosoma cruzi cdc2-related kinase 3 0.0213 0.0654 0.304
Schistosoma mansoni tyrosine kinase 0.0489 0.1868 0.3671
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0082 0.0078 0.0078
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0204 0.0616 0.0704
Echinococcus multilocularis hemicentin 1 0.0077 0.0056 0.0078
Echinococcus granulosus nervana 2 0.0253 0.0831 0.095
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0136 0.0318 0.0364
Giardia lamblia Kinase, AGC PKA 0.0119 0.0242 0.1197
Entamoeba histolytica hypothetical protein 0.0065 0.0002 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Loa Loa (eye worm) AGC/PKA protein kinase 0.0119 0.0242 0.0242
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0279 0.0947 0.186
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0279 0.0947 0.4689
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0279 0.0947 0.4458
Echinococcus multilocularis mitogen activated protein kinase 11 0.0295 0.1017 0.1408
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0432 0.2117
Trichomonas vaginalis AGC family protein kinase 0.0248 0.081 0.3974
Loa Loa (eye worm) CAMK protein kinase 0.0079 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0293 0.1009 0.1397
Brugia malayi WH1 domain containing protein 0.0064 0.0000058547 0.0000058547
Brugia malayi Variant SH3 domain containing protein 0.0109 0.0198 0.0198
Onchocerca volvulus 0.0286 0.0976 0.1905
Schistosoma mansoni neuroglian 0.0082 0.0078 0.0153
Loa Loa (eye worm) hypothetical protein 0.0203 0.0612 0.0612
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0209 0.0639 0.0639
Entamoeba histolytica serine/threonine protein kinase, putative 0.0083 0.0084 0.0414
Schistosoma mansoni growth factor receptor-bound protein 0.0109 0.0198 0.039
Echinococcus granulosus casein kinase I alpha 0.0115 0.0222 0.0254
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Trichomonas vaginalis CAMK family protein kinase 0.0523 0.2018 0.9898
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0143 0.0347 0.17
Echinococcus granulosus tyrosine kinase 0.0125 0.0266 0.0304
Schistosoma mansoni protein kinase 0.0101 0.0164 0.0322
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.1009 0.1153
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.094 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0776 0.3134 0.6158
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0083 0.0084 0.0133
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0136 0.0318 0.044
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0077 0.0056 0.0056
Trypanosoma cruzi Protein kinase B 0.0301 0.1044 0.5031
Brugia malayi cell division control protein 2 homolog 0.0213 0.0654 0.0654
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0164 0.0438 0.0607
Brugia malayi Protein kinase domain 0.0146 0.0359 0.0359
Brugia malayi Tyrosine-protein kinase abl-1 0.0336 0.1195 0.1195
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0322 0.1134 1
Entamoeba histolytica protein kinase, putative 0.0322 0.1134 0.556
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0776 0.3134 0.3583
Onchocerca volvulus 0.0167 0.0453 0.0883
Echinococcus granulosus tyrosine protein kinase shark 0.0125 0.0266 0.0304
Echinococcus granulosus casein kinase ii subunit alpha 0.0175 0.0486 0.0555
Entamoeba histolytica protein kinase, putative 0.0065 0.0002 0.001
Schistosoma mansoni transient receptor potential channel 0.0078 0.0059 0.0115
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0082 0.0078 0.0108
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0293 0.1009 0.1153
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0776 0.3134 0.4339
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0776 0.3134 0.3134
Brugia malayi SRC-1 0.0293 0.1009 0.1009
Echinococcus granulosus serine:threonine protein kinase 3 0.0495 0.1897 0.2169
Trypanosoma brucei protein kinase, putative 0.0141 0.0338 0.1299
Echinococcus multilocularis raf serine:threonine protein kinase 0.0134 0.0308 0.0427
Loa Loa (eye worm) hypothetical protein 0.0083 0.0085 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0876 0.1721
Schistosoma mansoni serine/threonine protein kinase 0.0523 0.2018 0.3966
Giardia lamblia Kinase, NEK 0.0248 0.081 0.4015
Trichomonas vaginalis CAMK family protein kinase 0.0523 0.2018 0.9898
Echinococcus multilocularis rac serine:threonine kinase 0.0301 0.1044 0.1446
Giardia lamblia Kinase, CMGC MAPK 0.0141 0.0338 0.1677
Echinococcus granulosus dual specificity testis-specific protein kinase 0.042 0.1564 0.1787
Echinococcus multilocularis growth factor receptor bound protein 2 0.0109 0.0198 0.0275
Loa Loa (eye worm) hypothetical protein 0.0117 0.0233 0.0233
Schistosoma mansoni tyrosine kinase 0.0173 0.0481 0.0945
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Echinococcus multilocularis PAK box P21 Rho binding 0.0064 0.0000058547 0.0000081041
Plasmodium falciparum protein kinase, putative 0.0101 0.0164 0.0754
Brugia malayi Furin-like cysteine rich region family protein 0.122 0.5088 0.5088
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0141 0.0338 0.1428
Brugia malayi serine/threonine-protein kinase PAK 7 0.0445 0.1674 0.1674
Echinococcus multilocularis tyrosine protein kinase otk 0.0077 0.0056 0.0078
Echinococcus granulosus tyrosine protein kinase Src42A 0.0293 0.1009 0.1153
Trichomonas vaginalis AGC family protein kinase 0.0528 0.2039 1
Entamoeba histolytica protein kinase, putative 0.0101 0.0164 0.0802
Trichomonas vaginalis CMGC family protein kinase 0.0213 0.0654 0.3209
Toxoplasma gondii aurora kinase 0.0322 0.1134 0.5642
Echinococcus multilocularis titin 0.0079 0.0064 0.0088
Echinococcus multilocularis serine:threonine protein kinase 3 0.0495 0.1897 0.2626
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0083 0.0085 0.0002
Trypanosoma cruzi casein kinase, putative 0.0115 0.0222 0.0835
Loa Loa (eye worm) hypothetical protein 0.007 0.0026 0.0026
Schistosoma mansoni protein kinase 0.042 0.1564 0.3073
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0263 0.0876 0.0876
Echinococcus granulosus unc 13 munc13 0.0073 0.0037 0.0042
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0115 0.0222 0.0222
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0146 0.0359 0.0497
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0064 0.0000058547 0.0000058547
Loa Loa (eye worm) hypothetical protein 0.0294 0.1011 0.1011
Loa Loa (eye worm) hypothetical protein 0.0284 0.0967 0.0967
Brugia malayi protein kinase C3,putative 0.0277 0.0936 0.0936
Entamoeba histolytica protein kinase domain containing protein 0.0175 0.0486 0.2383
Echinococcus multilocularis dual specificity testis specific protein kinase 0.042 0.1564 0.2165
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0364 0.132 0.132
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0019 0.0019
Echinococcus multilocularis NCK adaptor protein 0.0109 0.0198 0.0275
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0549 0.2134 0.2954
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0084 0.0166
Brugia malayi map kinase activated protein kinase protein 2 0.0776 0.3134 0.3134
Plasmodium vivax casein kinase 1, putative 0.0115 0.0222 0.1624
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0085 0.0167
Loa Loa (eye worm) hypothetical protein 0.0284 0.0967 0.0967
Entamoeba histolytica diacylglycerol kinase, putative 0.007 0.0026 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0432 0.0848
Brugia malayi SH2 domain containing protein 0.0125 0.0266 0.0266
Schistosoma mansoni nck2/grb4 0.0109 0.0198 0.039
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0245 0.0794 0.0908
Trypanosoma brucei casein kinase I, isoform 2 0.0115 0.0222 0.0704
Entamoeba histolytica PH domain containing protein kinase, putative 0.0301 0.1044 0.5122
Trichomonas vaginalis STE family protein kinase 0.0146 0.0359 0.176
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0059 0.0067
Schistosoma mansoni tyrosine kinase 0.0141 0.0339 0.0665
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0115 0.0222 0.0254
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0119 0.0242 0.0335
Echinococcus granulosus cyclin dependent kinase 0.0213 0.0654 0.0748
Schistosoma mansoni tyrosine kinase 0.047 0.1785 0.3509
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0082 0.0078 0.0108
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0119 0.0242 0.0242
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0083 0.0084 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Schistosoma mansoni protein kinase C 0.0073 0.0037 0.0073
Schistosoma mansoni protein kinase C mu 0.0274 0.0924 0.1817
Echinococcus multilocularis cyclin dependent kinase 5 0.0213 0.0654 0.0906
Leishmania major protein kinase A catalytic subunit 0.0119 0.0242 0.0813
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0083 0.0085 0.0301
Loa Loa (eye worm) hypothetical protein 0.0125 0.0266 0.0266
Trichomonas vaginalis AGC family protein kinase 0.0528 0.2039 1
Trichomonas vaginalis conserved hypothetical protein 0.0109 0.0195 0.0958
Echinococcus multilocularis lachesin 0.0077 0.0056 0.0078
Toxoplasma gondii AGC kinase 0.0516 0.1989 1
Entamoeba histolytica hypothetical protein 0.0065 0.0002 0.001
Plasmodium falciparum glycogen synthase kinase 3 0.0279 0.0947 0.8216
Echinococcus multilocularis tyrosine protein kinase Src42A 0.018 0.0512 0.0708
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0115 0.0222 0.0222
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0146 0.0359 0.041
Schistosoma mansoni cell adhesion molecule 0.0082 0.0078 0.0153
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0173 0.0481 0.0945
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0242 0.0475
Loa Loa (eye worm) hypothetical protein 0.0354 0.1276 0.1276
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0497 0.0978
Plasmodium falciparum protein kinase 5 0.0213 0.0654 0.543
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0083 0.0085 0.0301
Schistosoma mansoni cell adhesion molecule 0.0209 0.0638 0.1254
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0064 0.0125
Schistosoma mansoni ephrin receptor 0.0195 0.0577 0.1133
Echinococcus granulosus casein kinase I alpha 0.0115 0.0222 0.0254
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0626 0.2474 0.2474
Brugia malayi Protein kinase domain containing protein 0.0125 0.0266 0.0266
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0141 0.0338 0.1299
Loa Loa (eye worm) AGC/NDR protein kinase 0.0263 0.0876 0.0876
Trypanosoma brucei cdc2-related kinase 3 0.0213 0.0654 0.2915
Onchocerca volvulus Serine\/threonine kinase homolog 0.0523 0.2018 0.3938
Echinococcus granulosus short transient receptor potential channel 6 0.0078 0.0059 0.0067
Loa Loa (eye worm) hypothetical protein 0.0243 0.0789 0.0789
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0084 0.0166
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0082 0.0076 0.0076
Echinococcus granulosus Rac GTPase activating protein 1 0.007 0.0026 0.0029
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.047 0.1785 0.2471
Toxoplasma gondii AGC kinase 0.0119 0.0242 0.1099
Brugia malayi Protein kinase domain containing protein 0.0263 0.0876 0.0876
Loa Loa (eye worm) SRC-1 0.0293 0.1009 0.1009
Trichomonas vaginalis STE family protein kinase 0.0248 0.081 0.3974
Schistosoma mansoni septate junction protein 0.0077 0.0056 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0612 0.3001
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0242 0.0475
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0083 0.0085 0.0085
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0082 0.0078 0.0153
Trypanosoma cruzi casein kinase, putative 0.0115 0.0222 0.0835
Leishmania major protein kinase A catalytic subunit isoform 1 0.0119 0.0242 0.0813
Brugia malayi protein unc-22 0.0079 0.0064 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0486 0.2383
Loa Loa (eye worm) hypothetical protein 0.0226 0.0714 0.0714
Entamoeba histolytica protein kinase, putative 0.0113 0.0213 0.1045
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0318 0.156
Brugia malayi casein kinase I 0.0115 0.0222 0.0222
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0495 0.1897 0.1897
Echinococcus granulosus protein kinase c eta type 0.007 0.0026 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0685 0.1347
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0336 0.1195 0.1195
Trichomonas vaginalis CAMK family protein kinase 0.0523 0.2018 0.9898
Toxoplasma gondii casein kinase I 0.0115 0.0222 0.0999
Onchocerca volvulus Tyrosine kinase homolog 0.1229 0.5125 1
Loa Loa (eye worm) AUR protein kinase 0.0322 0.1134 0.1134
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0098 0.0147 0.0721
Schistosoma mansoni serine/threonine-protein kinase 0.0301 0.1044 0.2052
Echinococcus multilocularis transient receptor potential gamma protein 0.0117 0.0233 0.0323
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0119 0.0242 0.0276
Echinococcus granulosus serine:threonine protein kinase 0.0203 0.0612 0.07
Brugia malayi RhoGAP domain containing protein 0.013 0.0292 0.0292
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0109 0.0198 0.0198
Echinococcus multilocularis tyrosine protein kinase HCK 0.0184 0.0528 0.0731
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0083 0.0085 0.0301
Giardia lamblia Kinase, CMGC CK2 0.0175 0.0486 0.2407
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0523 0.2018 0.2018
Schistosoma mansoni serine/threonine-protein kinase 0.0301 0.1044 0.2052
Brugia malayi Protein kinase domain containing protein 0.0125 0.0266 0.0266
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0037 0.0037
Echinococcus multilocularis mitogen activated protein kinase 14 0.0295 0.1017 0.1408
Leishmania major protein kinase, putative 0.0101 0.0164 0.0409
Schistosoma mansoni atypical protein kinase C 0.0515 0.1985 0.3902
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0295 0.1017 0.1017
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0077 0.0056 0.0056
Echinococcus multilocularis peroxidasin 0.0077 0.0058 0.008
Brugia malayi Cam kinase protein 1 0.0083 0.0085 0.0085
Trichomonas vaginalis AGC family protein kinase 0.0263 0.0876 0.4295
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0446 0.1682 0.2328
Plasmodium vivax calcium-dependent protein kinase, putative 0.0083 0.0085 0.0364
Trypanosoma brucei cdc2-related kinase 1 0.0213 0.0654 0.2915
Brugia malayi Immunoglobulin I-set domain containing protein 0.0082 0.0078 0.0078
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0083 0.0085 0.0097
Echinococcus granulosus calcium activated potassium channel 0.0166 0.0449 0.0513
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0293 0.1009 0.1153
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0435 0.1633 0.1633
Schistosoma mansoni transient receptor potential channel 0.0078 0.0059 0.0115
Echinococcus multilocularis transient receptor potential ion channel A 0.0113 0.0216 0.0299
Plasmodium vivax unspecified product 0.0175 0.0486 0.4048
Echinococcus multilocularis calcium activated potassium channel 0.0166 0.0449 0.0621
Brugia malayi Pleckstrin Homology Domain 0.0081 0.0075 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0263 0.0876 0.4295
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.1163 0.2285
Brugia malayi jmjC domain containing protein 0.0115 0.0225 0.0225
Echinococcus granulosus RNA directed DNA polymerase 0.0081 0.0075 0.0085
Loa Loa (eye worm) hypothetical protein 0.0131 0.0294 0.0294
Onchocerca volvulus 0.0125 0.0266 0.0519
Loa Loa (eye worm) TK protein kinase 0.0245 0.0794 0.0794
Loa Loa (eye worm) hypothetical protein 0.0241 0.0777 0.0777
Schistosoma mansoni adapter molecule crk 0.0109 0.0198 0.039
Echinococcus granulosus ephrin type A receptor 4 A 0.0195 0.0577 0.0659
Schistosoma mansoni serine/threonine kinase 0.0263 0.0876 0.1721
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.0947 0.4642
Echinococcus multilocularis Immunoglobulin 0.0164 0.0438 0.0607
Echinococcus granulosus nervana 2 0.0253 0.0831 0.095
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0084 0.0166
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0253 0.0831 0.095
Leishmania major casein kinase II, putative 0.0175 0.0486 0.2076
Trypanosoma brucei aurora B kinase 0.0322 0.1134 0.5369
Echinococcus granulosus tyrosine kinase 0.0245 0.0794 0.0908
Loa Loa (eye worm) hypothetical protein 0.0284 0.0967 0.0967
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0322 0.1134 0.1569
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0119 0.0242 0.1498
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0328 0.1163 0.1609
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0143 0.0347 0.17
Brugia malayi Immunoglobulin I-set domain containing protein 0.0082 0.0078 0.0078
Giardia lamblia Kinase, PLK 0.0523 0.2018 1
Giardia lamblia Kinase, AGC AKT 0.0209 0.0639 0.3164
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0119 0.0242 0.1804
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0266 0.0889 0.1016
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0322 0.1134 0.1296
Trichomonas vaginalis AGC family protein kinase 0.0263 0.0876 0.4295
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.2052 0.8749 1
Brugia malayi RhoGAP domain containing protein 0.007 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0072 0.0033 0.0033
Echinococcus multilocularis dual specificity 0.022 0.0685 0.0948
Trichomonas vaginalis AGC family protein kinase 0.0322 0.1134 0.556
Echinococcus granulosus defective proboscis extension response 0.0164 0.0438 0.0501
Entamoeba histolytica protein kinase, putative 0.0115 0.0222 0.109
Trichomonas vaginalis CMGC family protein kinase 0.0175 0.0486 0.2383
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.029 0.0995 0.8676
Echinococcus granulosus myotubularin protein 13 0.0081 0.0075 0.0086
Brugia malayi Kinase associated domain 1 family protein 0.0125 0.0268 0.0268
Entamoeba histolytica PH domain containing protein kinase, putative 0.013 0.0291 0.1428
Schistosoma mansoni tyrosine kinase 0.0888 0.3624 0.7123
Entamoeba histolytica cell division protein kinase 2, putative 0.0213 0.0654 0.3209
Trichomonas vaginalis AGC family protein kinase 0.0322 0.1134 0.556
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0146 0.0359 0.041
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Plasmodium falciparum NIMA related kinase 1 0.0248 0.081 0.6918
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0101 0.0164 0.0702
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Echinococcus granulosus protein kinase c iota type 0.0503 0.1931 0.2207
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0019 0.0019
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0248 0.081 0.7029
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0338 0.0665
Brugia malayi serine/threonine kinase 12 0.0322 0.1134 0.1134
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0893 0.3646 0.5047
Echinococcus multilocularis serine threonine protein kinase 0.0347 0.1244 0.1722
Schistosoma mansoni titin 0.0077 0.0056 0.011
Loa Loa (eye worm) hypothetical protein 0.0204 0.0616 0.0616
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0083 0.0085 0.0118
Loa Loa (eye worm) hypothetical protein 0.0077 0.0056 0.0056
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.022 0.0685 0.3198
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0293 0.1009 0.1397
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0119 0.0242 0.0935
Loa Loa (eye worm) TK/INSR protein kinase 0.0888 0.3624 0.3624
Entamoeba histolytica protein kinase 2, putative 0.029 0.0995 0.4879
Entamoeba histolytica casein kinase, putative 0.0175 0.0486 0.2383
Loa Loa (eye worm) TK protein kinase 0.0506 0.1946 0.1946
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0723 0.1421
Echinococcus granulosus roundabout 2 0.0082 0.0078 0.0089
Echinococcus multilocularis hypothetical protein 0.0125 0.0268 0.0371
Loa Loa (eye worm) hypothetical protein 0.0183 0.0522 0.0522
Echinococcus multilocularis roundabout 2 0.0246 0.0799 0.1106
Loa Loa (eye worm) TK/FER protein kinase 0.0125 0.0266 0.0266
Schistosoma mansoni tyrosine kinase 0.122 0.5088 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0119 0.0242 0.0242
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0076 0.015
Schistosoma mansoni protein kinase 0.0101 0.0164 0.0321
Trichomonas vaginalis CAMK family protein kinase 0.0083 0.0084 0.0414
Schistosoma mansoni protein kinase 0.0146 0.0359 0.0705
Entamoeba histolytica protein kinase, putative 0.022 0.0685 0.336
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0381 0.1392 0.1392
Loa Loa (eye worm) AUR protein kinase 0.0322 0.1134 0.1134
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.132 0.2595
Echinococcus granulosus growth factor receptor bound protein 2 0.0109 0.0198 0.0227
Entamoeba histolytica protein kinase domain containing protein 0.0322 0.1134 0.556
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0077 0.0056 0.0056
Echinococcus multilocularis serine:threonine protein kinase N2 0.0263 0.0876 0.1212
Brugia malayi Prion-like- 0.0077 0.0056 0.0056

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) 0.8413 uM PUBCHEM_BIOASSAY: Confirmation dose response assay for compounds that activate transient receptor potential cation channel C4 (TRPC4). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2237, AID2259] ChEMBL. No reference
Potency (functional) 0.0112 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 5.0119 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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