Detailed information for compound 1391546

Basic information

Technical information
  • TDR Targets ID: 1391546
  • Name: oxalic acid; N-[(1-phenylpyrrol-2-yl)methyl]p rop-2-en-1-amine
  • MW: 302.325 | Formula: C16H18N2O4
  • H donors: 3 H acceptors: 4 LogP: -0.16 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(=O)O.C=CCNCc1cccn1c1ccccc1
  • InChi: 1S/C14H16N2.C2H2O4/c1-2-10-15-12-14-9-6-11-16(14)13-7-4-3-5-8-13;3-1(4)2(5)6/h2-9,11,15H,1,10,12H2;(H,3,4)(H,5,6)
  • InChiKey: NXBPZKQBKMVRJX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • oxalic acid; N-[(1-phenyl-2-pyrrolyl)methyl]prop-2-en-1-amine
  • allyl-[(1-phenylpyrrol-2-yl)methyl]amine; oxalic acid
  • ethanedioic acid; N-[(1-phenylpyrrol-2-yl)methyl]prop-2-en-1-amine
  • 5311-42-2
  • SMR000008549
  • Allyl-(1-phenyl-1H-pyrrol-2-ylmethyl)-amine
  • MLS000029291
  • BIM-0016823.P001

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0077 0.0191
Echinococcus granulosus serotonin transporter 0.0059 0.0507 0.0581
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0502 0.1011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0781 0.1008
Leishmania major beta tubulin 0.0023 0.01 0.0236
Schistosoma mansoni tubulin subunit beta 0.0023 0.01 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0077 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Brugia malayi jmjC domain containing protein 0.0115 0.1149 0.1134
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0028
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0045 0.5
Giardia lamblia Cathepsin B precursor 0.0025 0.0129 0.0159
Brugia malayi Bromodomain containing protein 0.0081 0.0759 0.0743
Giardia lamblia Cysteine protease 0.0025 0.0129 0.0159
Brugia malayi Tubulin beta-1 chain 0.0023 0.01 0.0083
Trypanosoma cruzi major cysteine proteinase, putative 0.0025 0.0129 0.0216
Brugia malayi prolyl oligopeptidase family protein 0.0169 0.176 0.1746
Schistosoma mansoni ap endonuclease 0.0057 0.0489 0.0607
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0781 0.0905
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0077 0.0059
Echinococcus granulosus biogenic amine 5HT receptor 0.0083 0.0781 0.0905
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0993 0.0978
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0025 0.0129 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.047 0.0537
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Schistosoma mansoni survival motor neuron protein 0.0048 0.0389 0.0475
Schistosoma mansoni histone deacetylase 0.0287 0.3086 0.403
Onchocerca volvulus Alhambra homolog 0.0035 0.0244 0.0735
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0489 0.1114
Onchocerca volvulus 0.0081 0.0757 0.2408
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0025 0.0129 0.0159
Leishmania major beta tubulin 0.0023 0.01 0.0236
Trichomonas vaginalis histone deacetylase, putative 0.0287 0.3086 0.801
Entamoeba histolytica cysteine protease, putative 0.0081 0.0757 0.1825
Echinococcus multilocularis snurportin 1 0.0303 0.3276 0.429
Echinococcus granulosus histone deacetylase 7 0.0191 0.2 0.2344
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0073 0.006
Leishmania major beta tubulin 0.0023 0.01 0.0236
Echinococcus multilocularis cathepsin L cysteine protease 0.0081 0.0757 0.0975
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.052 0.1458
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0077 0.0059
Echinococcus granulosus cathepsin l cysteine peptidase 0.0081 0.0757 0.0875
Loa Loa (eye worm) hypothetical protein 0.0055 0.0464 0.0447
Giardia lamblia Cysteine protease 0.0025 0.0129 0.0159
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0083 0.0781 0.1008
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0179 0.0162
Trypanosoma brucei RNA helicase, putative 0.0101 0.0988 0.3203
Schistosoma mansoni cathepsin s 0.0022 0.01 0.0095
Trichomonas vaginalis ran, putative 0.0021 0.0082 0.0033
Trichomonas vaginalis tubulin epsilon chain, putative 0.0023 0.01 0.0081
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0244 0.03
Onchocerca volvulus 0.0287 0.3086 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0209 0.0228
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.3276 0.3264
Brugia malayi Cathepsin L-like cysteine proteinase 0.0058 0.0502 0.0486
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0082 0.0065
Trypanosoma cruzi major cysteine proteinase, putative 0.0025 0.0129 0.0216
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0069 0.0037
Schistosoma mansoni neuropeptide receptor 0.0083 0.0781 0.0993
Echinococcus multilocularis allatostatin A receptor 0.0083 0.0781 0.1008
Trichomonas vaginalis glutaminase, putative 0.0269 0.2892 0.7495
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0781 0.0905
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0057 0.0489 0.0608
Echinococcus multilocularis histone deacetylase 6 0.0191 0.2 0.2611
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Brugia malayi hypothetical protein 0.0044 0.0338 0.0321
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Echinococcus multilocularis beta tubulin 0.0023 0.01 0.0111
Leishmania major histone deacetylase, putative 0.0191 0.2 0.6449
Schistosoma mansoni histone deacetylase 0.0287 0.3086 0.403
Echinococcus granulosus Dipeptidyl peptidase 9 0.0057 0.0489 0.0559
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0757 0.1825
Toxoplasma gondii beta-1 tubulin, putative 0.0023 0.01 0.006
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0025 0.0129 0.0278
Giardia lamblia Cathepsin B precursor 0.0151 0.1549 0.3929
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0106 0.0097
Echinococcus granulosus cathepsin b 0.0431 0.4719 0.5557
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0025 0.0129 0.0134
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0083 0.0781 0.0993
Echinococcus multilocularis histone deacetylase 1 0.0287 0.3086 0.404
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0138 0.0234
Brugia malayi cathepsin L-like precursor 0.0058 0.0502 0.0486
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0077 0.0191
Trypanosoma cruzi histone deacetylase, putative 0.0191 0.2 0.4203
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0112 0.0095
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0133 0.0155
Onchocerca volvulus Cathepsin L homolog 0.0025 0.0129 0.0364
Loa Loa (eye worm) ctsf protein 0.0081 0.0757 0.0741
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0431 0.4719 1
Schistosoma mansoni opsin-like receptor 0.0083 0.0781 0.0993
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0781 0.1008
Loa Loa (eye worm) hypothetical protein 0.0059 0.0507 0.0491
Plasmodium falciparum serine repeat antigen 2 0.0025 0.0129 0.0278
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0059
Brugia malayi Papain family cysteine protease containing protein 0.0048 0.0384 0.0367
Giardia lamblia Histone deacetylase 0.0287 0.3086 0.801
Trypanosoma brucei histone deacetylase 2 0.0107 0.1059 0.3432
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.063 0.0614
Plasmodium falciparum serine repeat antigen 5 0.0025 0.0129 0.0278
Loa Loa (eye worm) hypothetical protein 0.006 0.0528 0.0511
Leishmania major cathepsin L-like protease 0.0081 0.0757 0.2383
Echinococcus granulosus neuropeptide receptor 0.0083 0.0781 0.0905
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0081 0.0757 0.0741
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0049 0.0028
Brugia malayi Histone deacetylase family protein 0.0191 0.2 0.1986
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0077 0.0072
Onchocerca volvulus 0.0081 0.0757 0.2408
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0025 0.0129 0.0134
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0112
Plasmodium vivax serine-repeat antigen (SERA) 0.0025 0.0129 0.0278
Echinococcus granulosus cathepsin b 0.0431 0.4719 0.5557
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.1794 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0083 0.0781 0.1008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0083 0.0781 0.0993
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0069 0.0052
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0025 0.0129 0.0278
Brugia malayi PHD-finger family protein 0.0035 0.0244 0.0227
Echinococcus multilocularis orexin receptor type 2 0.0083 0.0781 0.1008
Brugia malayi Cathepsin L-like precursor 0.0081 0.0757 0.0741
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0209 0.0254
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0077 0.0059
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0112 0.0276
Echinococcus granulosus importin subunit beta 1 0.0028 0.0167 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0129 0.0159
Echinococcus multilocularis histone deacetylase 3 0.0287 0.3086 0.404
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0077 0.008
Brugia malayi Histone deacetylase 1 0.0287 0.3086 0.3074
Giardia lamblia Cysteine protease 0.0025 0.0129 0.0159
Loa Loa (eye worm) hypothetical protein 0.0201 0.2114 0.2101
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0431 0.4719 0.6184
Schistosoma mansoni neuropeptide receptor 0.0083 0.0781 0.0993
Entamoeba histolytica cysteine proteinase, putative 0.0048 0.0384 0.0835
Schistosoma mansoni tubulin subunit beta 0.0023 0.01 0.0095
Echinococcus granulosus cathepsin L 0.0025 0.0129 0.0134
Leishmania major beta tubulin 0.0023 0.01 0.0236
Loa Loa (eye worm) hypothetical protein 0.0236 0.2508 0.2495
Leishmania major cathepsin L-like protease 0.0081 0.0757 0.2383
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0059
Schistosoma mansoni hypothetical protein 0.0101 0.0988 0.1266
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0025 0.0129 0.0278
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Trichomonas vaginalis histone deacetylase, putative 0.0287 0.3086 0.801
Brugia malayi G protein-coupled receptor F59B2.13 0.0083 0.0781 0.0765
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.2508 0.3279
Onchocerca volvulus 0.0037 0.026 0.079
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0025 0.0129 0.0159
Loa Loa (eye worm) hypothetical protein 0.0083 0.0787 0.077
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0384 0.1244
Plasmodium falciparum cysteine proteinase falcipain 3 0.0081 0.0757 0.2341
Schistosoma mansoni cpg binding protein 0.0033 0.0221 0.0254
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0209 0.0254
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0025 0.0129 0.0159
Echinococcus multilocularis microtubule associated protein 2 0.0687 0.7614 1
Brugia malayi Cathepsin L-like precursor 0.0058 0.0502 0.0486
Toxoplasma gondii exonuclease III APE 0.0057 0.0489 0.1354
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0781 0.0905
Schistosoma mansoni hypothetical protein 0.0303 0.3276 0.4281
Loa Loa (eye worm) hypothetical protein 0.0043 0.0331 0.0315
Trypanosoma brucei histone deacetylase, putative 0.0191 0.2 0.6481
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Echinococcus multilocularis cathepsin b 0.0431 0.4719 0.619
Brugia malayi RNA, U transporter 1 0.0081 0.0759 0.0743
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0028
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0112 0.0102
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0244 0.0653
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Schistosoma mansoni ran 0.0021 0.0082 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0209 0.0192
Toxoplasma gondii beta tubulin 0.0023 0.01 0.006
Echinococcus granulosus G protein coupled receptor 139 0.0083 0.0781 0.0905
Echinococcus granulosus histone deacetylase 3 0.0287 0.3086 0.3627
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0112 0.0114
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0209 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Schistosoma mansoni alpha-1 adrenergic receptor 0.0083 0.0781 0.0993
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0077 0.0191
Echinococcus multilocularis histone deacetylase 6 0.0191 0.2 0.2611
Brugia malayi Dopamine receptor protein 2 0.0083 0.0781 0.0765
Echinococcus multilocularis neuropeptide s receptor 0.0083 0.0781 0.1008
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0077 0.0059
Echinococcus multilocularis cysteine protease 0.0081 0.0757 0.0975
Echinococcus multilocularis neuropeptide receptor 0.0083 0.0781 0.1008
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0077 0.0059
Loa Loa (eye worm) hypothetical protein 0.0024 0.0112 0.0095
Brugia malayi putative neuropeptide receptor NPR1 0.0083 0.0781 0.0765
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.1794 0.2647
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0082 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0025 0.0129 0.0159
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0045 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0781 0.1008
Leishmania major beta tubulin 0.0023 0.01 0.0236
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0209 0.0192
Brugia malayi Serotonin receptor 0.0083 0.0781 0.0765
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0106 0.0166
Brugia malayi N-terminal motif family protein 0.0185 0.194 0.1926
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3835 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0781 0.1008
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0077 0.0059
Giardia lamblia Beta tubulin 0.0023 0.01 0.0081
Leishmania major beta tubulin 0.0023 0.01 0.0236
Loa Loa (eye worm) jmjC domain-containing protein 0.0046 0.0369 0.0352
Plasmodium falciparum tubulin beta chain 0.0023 0.01 0.0181
Leishmania major beta tubulin 0.0023 0.01 0.0236
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Leishmania major importin beta-1 subunit, putative 0.0023 0.0106 0.0255
Schistosoma mansoni thyroid hormone receptor 0.002 0.0077 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.026 0.0306
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0077 0.0059
Entamoeba histolytica cysteine protease, putative 0.0025 0.0129 0.0159
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0369 0.045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0502 0.115
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0129 0.0159
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Echinococcus granulosus orexin receptor type 2 0.0083 0.0781 0.0905
Echinococcus granulosus microtubule associated protein 2 0.0687 0.7614 0.8977
Echinococcus multilocularis cathepsin L 0.0048 0.0384 0.0484
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0083 0.0781 0.1008
Brugia malayi cathepsin Z-like cysteine proteinase 0.0025 0.0129 0.0112
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0025 0.0129 0.0278
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0069 0.0055
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0567 0.0711
Brugia malayi cathepsin F-like cysteine proteinase 0.0025 0.0129 0.0112
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0112 0.0118
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0781 0.1008
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0069 0.0052
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0077 0.0064
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0069 0.0037
Entamoeba histolytica tubulin family protein 0.0023 0.01 0.0081
Trypanosoma cruzi histone deacetylase, putative 0.0107 0.1059 0.2197
Leishmania major DNA polymerase kappa, putative 0.002 0.0069 0.0136
Trypanosoma brucei ISWI complex protein 0.0016 0.0028 0.0091
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.3835 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0489 0.0472
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0069 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0077 0.0059
Toxoplasma gondii histone deacetylase HDAC2 0.0287 0.3086 1
Echinococcus multilocularis somatostatin receptor 0.0083 0.0781 0.1008
Echinococcus granulosus g protein coupled receptor 0.0083 0.0781 0.0905
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0781 0.1008
Trypanosoma cruzi histone deacetylase, putative 0.0107 0.1059 0.2197
Leishmania major cathepsin L-like protease 0.0081 0.0757 0.2383
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0057 0.0489 0.1586
Brugia malayi Papain family cysteine protease containing protein 0.0025 0.0129 0.0112
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Plasmodium falciparum histone deacetylase, putative 0.0191 0.2 0.6429
Brugia malayi cathepsin L-like cysteine proteinase 0.0025 0.0129 0.0112
Giardia lamblia Encystation-specific protease 0.0025 0.0129 0.0159
Loa Loa (eye worm) tubulin beta-2A chain 0.0023 0.01 0.0083
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.01 0.0083
Echinococcus granulosus somatostatin receptor 0.0083 0.0781 0.0905
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0069 0.0225
Brugia malayi jmjC domain containing protein 0.0046 0.0369 0.0352
Brugia malayi cathepsin L precursor 0.0025 0.0129 0.0112
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0083 0.0781 0.0765
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0025 0.0129 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0025 0.0129 0.0159
Entamoeba histolytica tubulin family protein 0.0023 0.01 0.0081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0059
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni ran 0.0021 0.0082 0.0071
Plasmodium falciparum serine repeat antigen 8 0.0025 0.0129 0.0278
Echinococcus multilocularis peregrin 0.0038 0.0272 0.0337
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.1794 0.2659
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0489 0.1114
Echinococcus multilocularis cathepsin b 0.0431 0.4719 0.619
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0238 0.0263
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0112 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0077 0.0059
Brugia malayi Bromodomain containing protein 0.004 0.0302 0.0285
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Onchocerca volvulus 0.0024 0.0112 0.0308
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.1149 0.1339
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0489 0.146
Schistosoma mansoni hypothetical protein 0.0083 0.0781 0.0993
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.026 0.0306
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0083 0.0781 0.0765
Trypanosoma cruzi cysteine proteinase, putative 0.0048 0.0384 0.0758
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0077 0.0059
Onchocerca volvulus 0.0081 0.0757 0.2408
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0083 0.0781 0.0905
Echinococcus granulosus hypothetical protein 0.0764 0.848 1
Onchocerca volvulus 0.0081 0.0757 0.2408
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0757 0.1553
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Plasmodium falciparum cysteine proteinase falcipain 1 0.0048 0.0384 0.1114
Schistosoma mansoni tubulin subunit beta 0.0023 0.01 0.0095
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0781 0.1008
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0059
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.026 0.0322
Entamoeba histolytica Ran family GTPase 0.0021 0.0082 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Schistosoma mansoni myosin xvIII 0.0083 0.0781 0.0993
Brugia malayi Pre-SET motif family protein 0.0037 0.026 0.0243
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0489 0.0559
Echinococcus granulosus fmrfamide receptor 0.0083 0.0781 0.0905
Leishmania major beta tubulin 0.0023 0.01 0.0236
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0049 0.0044
Brugia malayi Histone deacetylase family protein 0.0191 0.2 0.1986
Brugia malayi hypothetical protein 0.0026 0.0138 0.0121
Entamoeba histolytica cysteine proteinase 2 0.0048 0.0384 0.0835
Echinococcus granulosus snurportin 1 0.0303 0.3276 0.3851
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Giardia lamblia Cathepsin L precursor 0.0025 0.0129 0.0159
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0083 0.0781 0.0993
Onchocerca volvulus 0.0058 0.0502 0.1579
Loa Loa (eye worm) hypothetical protein 0.0022 0.01 0.0083
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0077 0.0064
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0757 0.2408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0025 0.0129 0.0159
Echinococcus multilocularis histone deacetylase 0.0191 0.2 0.2611
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.1149 0.1491
Plasmodium falciparum serine repeat antigen 9 0.0025 0.0129 0.0278
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Echinococcus multilocularis conserved hypothetical protein 0.0681 0.7544 0.9908
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0048 0.0384 0.0469
Entamoeba histolytica cysteine proteinase, putative 0.0048 0.0384 0.0835
Echinococcus multilocularis sex peptide receptor 0.0083 0.0781 0.1008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Echinococcus granulosus g-protein coupled receptor 0.0083 0.0781 0.0905
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0083 0.0781 0.1008
Giardia lamblia Cathepsin B precursor 0.0025 0.0129 0.0159
Brugia malayi ecdysteroid receptor 0.002 0.0077 0.0059
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0082 0.0065
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0048 0.0384 0.0469
Echinococcus multilocularis neuropeptide receptor 0.0083 0.0781 0.1008
Schistosoma mansoni amine GPCR 0.0083 0.0781 0.0993
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0167 0.0541
Echinococcus granulosus cpg binding protein 0.0033 0.0221 0.0242
Loa Loa (eye worm) beta-tubulin 0.0023 0.01 0.0083
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0112 0.0102
Brugia malayi histone deacetylase 1 (HD1) 0.0287 0.3086 0.3074
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0757 0.0741
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0781 0.1008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0055 0.0464 0.0574
Toxoplasma gondii beta-tubulin, putative 0.0023 0.01 0.006
Plasmodium falciparum serine repeat antigen 6 0.0025 0.0129 0.0278
Loa Loa (eye worm) solute carrier family 6 member 4 0.0059 0.0507 0.0491
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0025 0.0129 0.0278
Schistosoma mansoni tubulin subunit beta 0.0023 0.01 0.0095
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0048 0.0384 0.0469
Plasmodium vivax importin-beta 2, putative 0.0028 0.0167 0.0401
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0881 0.1124
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni hypothetical protein 0.0048 0.0389 0.0475
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0129 0.0159
Loa Loa (eye worm) histone deacetylase 0.0191 0.2 0.1986
Echinococcus granulosus alpha 1A adrenergic receptor 0.0083 0.0781 0.0905
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0083 0.0781 0.1008
Trichomonas vaginalis set domain proteins, putative 0.0287 0.3086 0.8011
Giardia lamblia Cathepsin B precursor 0.0151 0.1549 0.3929
Loa Loa (eye worm) prolyl oligopeptidase 0.0169 0.176 0.1746
Giardia lamblia Cathepsin L precursor 0.0025 0.0129 0.0159
Mycobacterium tuberculosis Probable oxidoreductase 0.0602 0.6654 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0083 0.0781 0.0993
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0069 0.0071
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0781 0.0905
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0057 0.0489 0.1356
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Trichomonas vaginalis tubulin gamma chain, putative 0.0023 0.01 0.0081
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0077 0.0064
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0059
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0025 0.0129 0.0278
Loa Loa (eye worm) hypothetical protein 0.0032 0.0209 0.0192
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0244 0.0269
Schistosoma mansoni histamine h1 receptor 0.0083 0.0781 0.0993
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Trichomonas vaginalis tubulin, putative 0.0023 0.01 0.0081
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0049 0.0039
Schistosoma mansoni histone deacetylase hda2 0.0191 0.2 0.2599
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0025 0.0129 0.0112
Schistosoma mansoni histone deacetylase 4 5 0.0191 0.2 0.2599
Schistosoma mansoni hypothetical protein 0.0022 0.0092 0.0084
Echinococcus granulosus dro:myosuppressin receptor 0.0083 0.0781 0.0905
Leishmania major cysteine peptidase A (CPA) 0.0081 0.0757 0.2383
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0781 0.0993
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0025 0.0129 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0025 0.0129 0.0159
Schistosoma mansoni hypothetical protein 0.042 0.4591 0.6015
Echinococcus granulosus neuropeptide receptor 0.0083 0.0781 0.0905
Echinococcus granulosus tubulin beta 4A class IVa 0.0023 0.01 0.01
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0209 0.0228
Echinococcus granulosus histone deacetylase 6 0.0191 0.2 0.2344
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0781 0.0905
Leishmania major beta tubulin 0.0023 0.01 0.0236
Brugia malayi Cathepsin L-like precursor 0.0081 0.0757 0.0741
Toxoplasma gondii cathepsin CPC2 0.0025 0.0129 0.0158
Echinococcus multilocularis fmrfamide receptor 0.0083 0.0781 0.1008
Echinococcus granulosus serotonin receptor 0.0083 0.0781 0.0905
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0081 0.0757 0.0975
Leishmania major cathepsin L-like protease 0.0081 0.0757 0.2383
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0059
Leishmania major histone deacetylase, putative 0.0287 0.3086 1
Trypanosoma brucei histone deacetylase 4 0.0191 0.2 0.6481
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.3835 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0049 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0077 0.0059
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0057 0.0489 0.1586
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0077 0.0064
Giardia lamblia Cathepsin B precursor 0.0025 0.0129 0.0159
Loa Loa (eye worm) hypothetical protein 0.0044 0.0338 0.0321
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0082 0.0115
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0025 0.0129 0.0134
Loa Loa (eye worm) hypothetical protein 0.0083 0.0787 0.077
Echinococcus granulosus neuropeptide Y receptor 0.0083 0.0781 0.0905
Schistosoma mansoni cathepsin F (C01 family) 0.0058 0.0502 0.0625
Echinococcus granulosus cathepsin L cysteine protease 0.0048 0.0384 0.0435
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0083 0.0781 0.0765
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0057 0.0489 0.0623
Echinococcus granulosus 7TM GPCR rhodopsin 0.0083 0.0781 0.0905
Schistosoma mansoni hypothetical protein 0.0032 0.0209 0.0238
Schistosoma mansoni hypothetical protein 0.0032 0.0209 0.0238
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0025 0.0129 0.0278
Schistosoma mansoni nuclear hormone receptor 0.002 0.0077 0.0064
Loa Loa (eye worm) hypothetical protein 0.0058 0.0502 0.0486
Trypanosoma brucei unspecified product 0.002 0.0069 0.0225
Schistosoma mansoni DNA polymerase eta 0.002 0.0069 0.0055
Schistosoma mansoni cpg binding protein 0.0029 0.0179 0.0199
Onchocerca volvulus 0.002 0.0077 0.0191
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0048 0.0384 0.0758
Loa Loa (eye worm) hypothetical protein 0.004 0.0303 0.0286
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Loa Loa (eye worm) tubulin beta-1 chain 0.0023 0.01 0.0083
Loa Loa (eye worm) hypothetical protein 0.0107 0.1059 0.1043
Giardia lamblia Hypothetical protein 0.0025 0.0129 0.0159
Brugia malayi larval opioid receptor 0.0083 0.0781 0.0765
Entamoeba histolytica cysteine proteinase 1, putative 0.0048 0.0384 0.0835
Toxoplasma gondii cathepsin CPL 0.0081 0.0757 0.2246
Echinococcus granulosus dna polymerase eta 0.002 0.0069 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Echinococcus multilocularis dna polymerase kappa 0.002 0.0069 0.0071
Loa Loa (eye worm) cysteine protease 0.0081 0.0757 0.0741
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.047 0.0598
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.047 0.0453
Echinococcus multilocularis neuropeptide Y receptor 0.0083 0.0781 0.1008
Schistosoma mansoni cathepsin S (C01 family) 0.0025 0.0129 0.0134
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0083 0.0781 0.0993
Echinococcus granulosus neuropeptide FF receptor 2 0.0083 0.0781 0.0905
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Onchocerca volvulus 0.0083 0.0781 0.2489
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0489 0.0672
Echinococcus multilocularis beta tubulin 0.0023 0.01 0.0111
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0244 0.0538
Brugia malayi Papain family cysteine protease containing protein 0.0025 0.0129 0.0112
Onchocerca volvulus 0.0083 0.0781 0.2489
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0138 0.0447
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Toxoplasma gondii preprocathepsin c precursor, putative 0.0025 0.0129 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0077 0.0059
Schistosoma mansoni opsin-like receptor 0.0083 0.0781 0.0993
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.01 0.0111
Echinococcus granulosus histone deacetylase 0.0191 0.2 0.2344
Echinococcus granulosus GPCR family 2 0.0032 0.0209 0.0228
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0112 0.0114
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0077 0.0072
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0057 0.0489 0.0983
Entamoeba histolytica cysteine protease, putative 0.0025 0.0129 0.0159
Schistosoma mansoni hypothetical protein 0.0083 0.0781 0.0993
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0082 0.0087
Onchocerca volvulus 0.0083 0.0781 0.2489
Echinococcus granulosus neuropeptide receptor A26 0.0083 0.0781 0.0905
Trypanosoma cruzi histone deacetylase 1, putative 0.0287 0.3086 0.6517
Schistosoma mansoni cathepsin C 0.0025 0.0129 0.0134
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0781 0.0905
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Leishmania major beta tubulin 0.0023 0.01 0.0236
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0081 0.0757 0.2341
Entamoeba histolytica cysteine proteinase, putative 0.0048 0.0384 0.0835
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0077 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Echinococcus multilocularis dna polymerase eta 0.002 0.0069 0.0071
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Loa Loa (eye worm) TYRA-2 protein 0.0083 0.0781 0.0765
Brugia malayi prolyl oligopeptidase family protein 0.0057 0.0489 0.0473
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0055 0.0464 0.0589
Plasmodium vivax unspecified product 0.0048 0.0384 0.1114
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0025 0.0129 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3835 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0077 0.0072
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0138 0.0306
Loa Loa (eye worm) hypothetical protein 0.0028 0.0167 0.015
Echinococcus multilocularis g-protein coupled receptor 0.0083 0.0781 0.1008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0151 0.1549 0.2005
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0083 0.0781 0.1008
Loa Loa (eye worm) hypothetical protein 0.0059 0.0507 0.0491
Loa Loa (eye worm) hypothetical protein 0.0058 0.0502 0.0486
Echinococcus multilocularis fmrfamide receptor 0.0083 0.0781 0.1008
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0489 0.0623
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0077 0.0059
Schistosoma mansoni ap endonuclease 0.0057 0.0489 0.0607
Giardia lamblia PHD finger protein 15 0.0035 0.0244 0.0462
Trichomonas vaginalis histone deacetylase, putative 0.0287 0.3086 0.801
Brugia malayi cathepsin B-like cysteine proteinase 0.0431 0.4719 0.471
Plasmodium vivax tubulin beta chain, putative 0.0023 0.01 0.0181
Echinococcus granulosus tachykinin peptides receptor 99D 0.0083 0.0781 0.0905
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0077 0.008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0112
Plasmodium falciparum serine repeat antigen 7 0.0025 0.0129 0.0278
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Echinococcus multilocularis dnaJ subfamily B 0.042 0.4591 0.6022
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Loa Loa (eye worm) tubulin beta chain 0.0023 0.01 0.0083
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0083 0.0781 0.0993
Plasmodium vivax vivapain-2 0.0081 0.0757 0.2341
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Onchocerca volvulus 0.0029 0.0179 0.0524
Schistosoma mansoni biogenic amine receptor 0.0083 0.0781 0.0993
Brugia malayi G-protein coupled receptor 0.0083 0.0781 0.0765
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0069 0.0053
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Brugia malayi fibroinase precursor 0.0025 0.0129 0.0112
Brugia malayi RE15519p 0.0083 0.0781 0.0765
Trypanosoma brucei beta tubulin 0.0023 0.01 0.0324
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0059 0.0507 0.0632
Mycobacterium ulcerans glutaminase 0.0269 0.2892 0.4307
Echinococcus granulosus histone deacetylase 1 0.0287 0.3086 0.3627
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni amine GPCR 0.0083 0.0781 0.0993
Leishmania major beta tubulin 0.0023 0.01 0.0236
Onchocerca volvulus Neuropeptide F receptor homolog 0.0083 0.0781 0.2489
Echinococcus granulosus tubulin beta 1 chain 0.0023 0.01 0.01
Brugia malayi nuclear hormone receptor 0.002 0.0077 0.0059
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0389 0.0372
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0077 0.0064
Echinococcus multilocularis cysteine protease 0.0081 0.0757 0.0975
Loa Loa (eye worm) cathepsin B 0.0151 0.1549 0.1534
Onchocerca volvulus 0.0083 0.0781 0.2489
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0077 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Echinococcus multilocularis neuropeptides capa receptor 0.0083 0.0781 0.1008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0112
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0112 0.0102
Giardia lamblia Cathepsin L precursor 0.0025 0.0129 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0129 0.0159
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0077 0.0064
Plasmodium vivax SET domain protein, putative 0.0037 0.026 0.0708
Mycobacterium ulcerans hypothetical protein 0.0024 0.0112 0.0102
Giardia lamblia Cathepsin B precursor 0.0025 0.0129 0.0159
Brugia malayi glutaminase DH11.1 0.0269 0.2892 0.2879
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0055 0.0464 0.0574
Brugia malayi hypothetical protein 0.0236 0.2508 0.2495
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0112 0.0276
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0083 0.0781 0.1008
Brugia malayi steroid hormone receptor 0.002 0.0077 0.0059
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.01 0.0111
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0077 0.0059
Trypanosoma cruzi beta tubulin, putative 0.0023 0.01 0.0154
Echinococcus multilocularis neuropeptide receptor A26 0.0083 0.0781 0.1008
Brugia malayi AKH receptor 0.0083 0.0781 0.0765
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0167 0.0199
Brugia malayi putative neuropeptide receptor 0.0083 0.0781 0.0765
Echinococcus granulosus neuropeptides capa receptor 0.0083 0.0781 0.0905
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0069 0.0053
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.01 0.0111
Brugia malayi hypothetical protein 0.0017 0.0034 0.0017
Echinococcus granulosus peptide allatostatin:somatostatin 0.0083 0.0781 0.0905
Schistosoma mansoni growth hormone secretagogue receptor 0.0083 0.0781 0.0993
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0077 0.008
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0077 0.0064
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0077 0.0059
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.01 0.0111
Leishmania major hypothetical protein, conserved 0.0026 0.0138 0.036
Plasmodium vivax histone deacetylase 1, putative 0.0287 0.3086 1
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0399 0.0453
Loa Loa (eye worm) hypothetical protein 0.0201 0.2114 0.2101
Loa Loa (eye worm) hypothetical protein 0.0022 0.01 0.0083
Brugia malayi Melatonin receptor type 1A 0.0083 0.0781 0.0765
Echinococcus granulosus dna polymerase kappa 0.002 0.0069 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0077 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Echinococcus granulosus cathepsin l1 0.0081 0.0757 0.0875
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0115 0.0098
Echinococcus multilocularis tubulin beta 1 chain 0.0023 0.01 0.0111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3835 1
Brugia malayi neuropeptide F receptor 0.0083 0.0781 0.0765
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0274 0.0305
Schistosoma mansoni thyroid hormone receptor 0.002 0.0077 0.0064
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0106 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Schistosoma mansoni sodium/chloride dependent transporter 0.0059 0.0507 0.0632
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0083 0.0781 0.0993
Trypanosoma cruzi histone deacetylase, putative 0.0191 0.2 0.4203
Schistosoma mansoni biogenic amine receptor 0.0083 0.0781 0.0993
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0129 0.0159
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0781 0.1008
Schistosoma mansoni hypothetical protein 0.0083 0.0781 0.0993
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0028
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0025 0.0129 0.0278
Plasmodium vivax unspecified product 0.0022 0.01 0.018
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0489 0.0982
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0489 0.146
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0082 0.0033
Echinococcus granulosus beta tubulin 0.0023 0.01 0.01
Brugia malayi nuclear receptor NHR-88 0.002 0.0077 0.0059
Brugia malayi Cathepsin L-like precursor 0.0081 0.0757 0.0741
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0757 0.1553
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Toxoplasma gondii histone deacetylase HDAC1 0.0191 0.2 0.6385
Echinococcus granulosus lysine specific demethylase 5A 0.0046 0.0369 0.0417
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0083 0.0781 0.0765
Schistosoma mansoni opsin-like receptor 0.0083 0.0781 0.0993
Trichomonas vaginalis tubulin beta chain, putative 0.0023 0.01 0.0081
Brugia malayi sulfakinin receptor protein 0.0083 0.0781 0.0765
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Loa Loa (eye worm) glutaminase 0.0269 0.2892 0.2879
Schistosoma mansoni cathepsin B (C01 family) 0.0025 0.0129 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0048 0.0384 0.0835
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0489 0.1507
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0225
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0993 0.0978
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0169 0.176 0.5678
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0077 0.0059
Echinococcus granulosus allatostatin A receptor 0.0083 0.0781 0.0905
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0077 0.0072
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0057 0.0489 0.1509
Entamoeba histolytica histone deacetylase, putative 0.0287 0.3086 0.801
Onchocerca volvulus 0.0059 0.0507 0.1595
Schistosoma mansoni neuropeptide receptor 0.0083 0.0781 0.0993
Schistosoma mansoni adenoreceptor 0.0083 0.0781 0.0993
Schistosoma mansoni hypothetical protein 0.0069 0.063 0.0794
Echinococcus granulosus dnaJ subfamily B 0.042 0.4591 0.5406
Plasmodium vivax serine-repeat antigen (SERA) 0.0025 0.0129 0.0278
Loa Loa (eye worm) tubulin beta-4 chain 0.0023 0.01 0.0083
Brugia malayi G-protein coupled receptor 0.0083 0.0781 0.0765
Entamoeba histolytica cysteine proteinase, putative 0.0048 0.0384 0.0835
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0052
Trypanosoma cruzi cysteine proteinase, putative 0.0048 0.0384 0.0758
Loa Loa (eye worm) hypothetical protein 0.0022 0.01 0.0083
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3835 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0082 0.0266
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0781 0.0905
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0667 0.0651
Brugia malayi Serotonin receptor 0.0537 0.5914 0.5907
Leishmania major cathepsin L-like protease 0.0081 0.0757 0.2383
Onchocerca volvulus 0.0083 0.0781 0.2489
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.2694 0.2681
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0069 0.0063
Brugia malayi histone deacetylase 3 (HD3) 0.0287 0.3086 0.3074
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0287 0.3086 0.801
Plasmodium falciparum histone deacetylase 2 0.0191 0.2 0.6429
Schistosoma mansoni neuropeptide F-like receptor 0.0083 0.0781 0.0993
Loa Loa (eye worm) hypothetical protein 0.0024 0.0112 0.0095
Schistosoma mansoni tubulin subunit beta 0.0023 0.01 0.0095
Schistosoma mansoni histone deacetylase hda2 0.0107 0.1059 0.1359
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0757 0.2408
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0287 0.3086 0.801
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Leishmania major beta tubulin 0.0023 0.01 0.0236
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0287 0.3086 0.801
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0244 0.0227
Onchocerca volvulus 0.0081 0.0757 0.2408
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0169 0.176 0.2296
Toxoplasma gondii cathepsin CPC1 0.0025 0.0129 0.0158
Plasmodium vivax vivapain-1 0.0048 0.0384 0.1114
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0577 0.0662
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0077 0.008
Brugia malayi Papain family cysteine protease containing protein 0.0025 0.0129 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0048 0.0384 0.0835
Echinococcus granulosus FTZ F1 alpha 0.002 0.0077 0.0072
Brugia malayi Pre-SET motif family protein 0.0252 0.2694 0.2681
Leishmania major cathepsin L-like protease 0.0081 0.0757 0.2383
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0025 0.0129 0.0134
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0781 0.0993
Schistosoma mansoni histone deacetylase 1 2 3 0.0107 0.1059 0.1359
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0133 0.0139
Treponema pallidum sodium- and chloride- dependent transporter 0.0059 0.0507 0.0055
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0057 0.0489 0.0983
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0312 0.3371 0.336
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0083 0.0781 0.0905
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Plasmodium vivax vivapain-2 0.0081 0.0757 0.2341
Loa Loa (eye worm) fibroinase 0.0081 0.0757 0.0741
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Trypanosoma brucei cysteine peptidase C (CPC) 0.0151 0.1549 0.502
Echinococcus granulosus neuropeptides capa receptor 0.0083 0.0781 0.0905
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0112
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0028
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0025 0.0129 0.0134
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0431 0.4719 0.6184
Echinococcus multilocularis histone deacetylase 6 0.0191 0.2 0.2611
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0083 0.0781 0.0993
Loa Loa (eye worm) BEN-1 protein 0.0023 0.01 0.0083
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.3835 1
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0757 0.1553
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0077 0.0072
Echinococcus granulosus biogenic amine 5HT receptor 0.0201 0.2114 0.2479
Entamoeba histolytica cysteine protease, putative 0.0025 0.0129 0.0159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3835 1
Loa Loa (eye worm) histone deacetylase 3 0.0287 0.3086 0.3074
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0138 0.0186
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0112 0.0114
Entamoeba histolytica cysteine protease, putative 0.0025 0.0129 0.0159
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Onchocerca volvulus 0.0083 0.0781 0.2489
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0129 0.0159
Brugia malayi Cathepsin L-like precursor 0.0081 0.0757 0.0741
Plasmodium falciparum serine repeat antigen 4 0.0025 0.0129 0.0278
Plasmodium vivax vivapain-3 0.0048 0.0384 0.1114
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0129 0.0159
Toxoplasma gondii histone deacetylase HDAC3 0.0287 0.3086 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Echinococcus granulosus cathepsin L cysteine proteinase 0.0081 0.0757 0.0875
Trichomonas vaginalis tubulin epsilon chain, putative 0.0023 0.01 0.0081
Echinococcus granulosus cathepsin L 0.0048 0.0384 0.0435
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Plasmodium vivax unspecified product 0.0025 0.0129 0.0278
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0025 0.0129 0.0112
Entamoeba histolytica hypothetical protein 0.0023 0.0106 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0129 0.0159
Echinococcus granulosus histone deacetylase 8 0.0107 0.1059 0.1232
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0082 0.0122
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0088
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0757 0.1825
Plasmodium falciparum importin beta, putative 0.0028 0.0167 0.0401
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.3835 1
Leishmania major beta tubulin 0.0023 0.01 0.0236
Onchocerca volvulus 0.0083 0.0781 0.2489
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0069 0.0136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0077 0.0059
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0059 0.0507 0.0491
Brugia malayi Dopamine receptor 0.0083 0.0781 0.0765
Giardia lamblia Beta tubulin 0.0023 0.01 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0025 0.0129 0.0159
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0081 0.0757 0.0975
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0088
Brugia malayi hypothetical protein 0.0083 0.0781 0.0765
Onchocerca volvulus 0.0083 0.0781 0.2489
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0081 0.0757 0.2341
Loa Loa (eye worm) hypothetical protein 0.0287 0.3086 0.3074
Schistosoma mansoni histone deacetylase 4 5 0.0191 0.2 0.2599
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0781 0.1008
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Trypanosoma brucei histone deacetylase 1 0.0287 0.3086 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0151 0.1549 0.4975
Brugia malayi G protein-coupled receptor 0.0083 0.0781 0.0765
Schistosoma mansoni bromodomain containing protein 0.0068 0.0619 0.0779
Echinococcus multilocularis tubulin subunit beta 0.0023 0.01 0.0111
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Onchocerca volvulus 0.0083 0.0781 0.2489
Trypanosoma brucei histone deacetylase 3 0.0191 0.2 0.6481
Schistosoma mansoni amine GPCR 0.0083 0.0781 0.0993
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0577 0.0738
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.01 0.0083
Entamoeba histolytica cysteine protease, putative 0.0025 0.0129 0.0159
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.01 0.01
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0274 0.034
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0167 0.0541
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.047 0.0537
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0781 0.1008
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0077 0.008
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.2508 0.2944
Echinococcus multilocularis cathepsin L 0.0025 0.0129 0.015
Loa Loa (eye worm) hypothetical protein 0.0058 0.0502 0.0486
Loa Loa (eye worm) hypothetical protein 0.0026 0.0138 0.0121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Schistosoma mansoni tubulin subunit beta 0.0023 0.01 0.0095
Onchocerca volvulus 0.0083 0.0781 0.2489
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0781 0.1008
Onchocerca volvulus 0.0083 0.0781 0.2489
Brugia malayi Importin beta-1 subunit 0.0028 0.0167 0.015
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0083 0.0781 0.0765
Echinococcus multilocularis neuropeptide Y receptor 0.0083 0.0781 0.1008
Onchocerca volvulus 0.0083 0.0781 0.2489
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0059
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0244 0.0538
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0112
Echinococcus multilocularis zinc finger protein 0.0022 0.0098 0.0108
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0077 0.0072
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0083 0.0781 0.1008
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0083 0.0781 0.0765
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0077 0.0064
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0077 0.008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0431 0.4719 0.6184
Loa Loa (eye worm) glutaminase 2 0.0269 0.2892 0.2879
Brugia malayi cathepsin Z-like cysteine proteinase 0.0025 0.0129 0.0112
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0025 0.0129 0.0112
Entamoeba histolytica cysteine protease, putative 0.0025 0.0129 0.0159
Loa Loa (eye worm) histone deacetylase 7A 0.0191 0.2 0.1986
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0077 0.0059
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0023 0.01 0.0111
Brugia malayi Cathepsin L-like precursor 0.0022 0.01 0.0083
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0077 0.008
Trichomonas vaginalis tubulin alpha chain, putative 0.0023 0.01 0.0081
Giardia lamblia Cathepsin L precursor 0.0025 0.0129 0.0159
Giardia lamblia Beta tubulin 0.0023 0.01 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0781 0.0993
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3835 1
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0056 0.0039
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0399 0.0505
Echinococcus multilocularis cpg binding protein 0.0033 0.0221 0.0269
Onchocerca volvulus 0.0081 0.0757 0.2408
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0151 0.1549 0.3929
Loa Loa (eye worm) hypothetical protein 0.0047 0.0373 0.0356
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0138 0.0234
Toxoplasma gondii cathepsin B 0.0151 0.1549 0.4884
Echinococcus granulosus sex peptide receptor 0.0083 0.0781 0.0905
Onchocerca volvulus 0.0083 0.0781 0.2489
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0781 0.0993
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0384 0.1244
Leishmania major beta tubulin 0.0023 0.01 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0112 0.0095
Schistosoma mansoni cpg binding protein 0.0033 0.0221 0.0254
Schistosoma mansoni neuropeptide f receptor 76f 0.0083 0.0781 0.0993
Leishmania major beta tubulin 0.0023 0.01 0.0236
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0898 1 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0055 0.0464 0.0529
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3835 1
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0431 0.4719 0.6184
Plasmodium vivax histone deacetylase, putative 0.0191 0.2 0.6429
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0082 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0025 0.0129 0.0159
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0092 0.0074
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0781 0.0905
Schistosoma mansoni hypothetical protein 0.0032 0.0209 0.0238
Schistosoma mansoni amine GPCR 0.0083 0.0781 0.0993
Onchocerca volvulus 0.0083 0.0781 0.2489
Schistosoma mansoni hypothetical protein 0.0032 0.0209 0.0238
Loa Loa (eye worm) hypothetical protein 0.0185 0.194 0.1926
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0169 0.176 0.2061
Trypanosoma cruzi cysteine peptidase, putative 0.0022 0.01 0.0153
Schistosoma mansoni biogenic amine receptor 0.0083 0.0781 0.0993
Echinococcus multilocularis serotonin receptor 0.0201 0.2114 0.2762
Echinococcus multilocularis histone deacetylase 8 0.0107 0.1059 0.1373
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0077 0.0059
Trichomonas vaginalis histone deacetylase, putative 0.0287 0.3086 0.801
Trypanosoma cruzi histone deacetylase, putative 0.0191 0.2 0.4203
Schistosoma mansoni hypothetical protein 0.0035 0.0244 0.0284
Loa Loa (eye worm) histone deacetylase 1 0.0287 0.3086 0.3074
Leishmania major histone deacetylase, putative 0.0287 0.3086 1
Onchocerca volvulus 0.0025 0.0129 0.0364
Echinococcus granulosus neuropeptide s receptor 0.0083 0.0781 0.0905
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0077 0.0059
Echinococcus multilocularis GPCR, family 2 0.0032 0.0209 0.0254
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0781 0.1008
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0502 0.115
Echinococcus granulosus g protein coupled receptor 0.0083 0.0781 0.0905
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0025 0.0129 0.0278
Trypanosoma cruzi cruzipain precursor, putative 0.0022 0.01 0.0153
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0083 0.0781 0.0905
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0083 0.0781 0.0765
Trichomonas vaginalis histone deacetylase, putative 0.0287 0.3086 0.801
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0781 0.0905
Brugia malayi beta-tubulin, identical 0.0023 0.01 0.0083
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0025 0.0129 0.0159
Echinococcus multilocularis neuropeptide FF receptor 2 0.0083 0.0781 0.1008
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0489 0.0472
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.3835 1
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0489 0.0687
Onchocerca volvulus 0.0083 0.0781 0.2489
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Leishmania major cathepsin L-like protease 0.0081 0.0757 0.2383
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0489 0.0982
Brugia malayi Papain family cysteine protease containing protein 0.0048 0.0384 0.0367
Echinococcus granulosus g protein coupled receptor 0.0083 0.0781 0.0905
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0083 0.0781 0.1008
Schistosoma mansoni glutaminase 0.0269 0.2892 0.3775
Echinococcus multilocularis cathepsin L cysteine protease 0.0081 0.0757 0.0975
Trichomonas vaginalis histone deacetylase, putative 0.0287 0.3086 0.801
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0077 0.0059
Brugia malayi PHD-finger family protein 0.0028 0.0162 0.0144
Onchocerca volvulus 0.0048 0.0389 0.1208
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0083 0.0781 0.2489
Mycobacterium ulcerans short chain dehydrogenase 0.0602 0.6654 1
Loa Loa (eye worm) histone deacetylase 11 0.0107 0.1059 0.1043
Trypanosoma cruzi cysteine peptidase, putative 0.0048 0.0384 0.0758
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.01 0.0083
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Schistosoma mansoni amine GPCR 0.0083 0.0781 0.0993
Schistosoma mansoni neuropeptide F-like receptor 0.0083 0.0781 0.0993
Trypanosoma brucei beta tubulin 0.0023 0.01 0.0324
Loa Loa (eye worm) neuropeptide F receptor 0.0083 0.0781 0.0765
Giardia lamblia Cysteine protease 0.0025 0.0129 0.0159
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0327 0.041
Plasmodium falciparum serine repeat antigen 1 0.0025 0.0129 0.0278
Brugia malayi follicle stimulating hormone receptor 0.0312 0.3371 0.336
Loa Loa (eye worm) hypothetical protein 0.0069 0.063 0.0614
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0083 0.0781 0.0993
Giardia lamblia Cathepsin L-like protease 0.0025 0.0129 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Leishmania major beta tubulin 0.0023 0.01 0.0236
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Loa Loa (eye worm) BEN-1 protein 0.0023 0.01 0.0083
Echinococcus granulosus histone deacetylase 6 0.0191 0.2 0.2344
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0083 0.0781 0.0905
Toxoplasma gondii histone deacetylase HDAC5 0.0107 0.1059 0.3252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0502 0.115
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0025 0.0129 0.0112
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0083 0.0781 0.0993
Echinococcus multilocularis G protein coupled receptor 139 0.0083 0.0781 0.1008
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0083 0.0781 0.0765
Leishmania major beta tubulin 0.0023 0.01 0.0236
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0083 0.0781 0.1008
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0077 0.0064
Echinococcus granulosus neuropeptide Y receptor 0.0083 0.0781 0.0905
Loa Loa (eye worm) hypothetical protein 0.0075 0.0689 0.0673
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0083 0.0781 0.0905
Loa Loa (eye worm) hypothetical protein 0.0102 0.0993 0.0978
Echinococcus granulosus tubulin subunit beta 0.0023 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.002 0.0077 0.0059
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.01 0.01
Brugia malayi Cathepsin L-like precursor 0.0058 0.0502 0.0486
Schistosoma mansoni cathepsin F (C01 family) 0.0081 0.0757 0.0961
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0081 0.0757 0.1825
Plasmodium falciparum phd finger protein, putative 0.0035 0.0244 0.0653
Loa Loa (eye worm) hypothetical protein 0.0081 0.0757 0.0741
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.047 0.0453
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0138 0.0306
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.047 0.0583
Leishmania major GTP-binding protein, putative 0.0021 0.0082 0.0177
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0993 0.0978
Loa Loa (eye worm) G-protein coupled receptor 0.0083 0.0781 0.0765
Echinococcus multilocularis serotonin receptor 0.0201 0.2114 0.2762
Trypanosoma cruzi histone deacetylase 1, putative 0.0287 0.3086 0.6517
Loa Loa (eye worm) hypothetical protein 0.0059 0.0507 0.0491
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0083 0.0781 0.0765
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0025 0.0129 0.0134
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0025 0.0129 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Toxoplasma gondii histone deacetylase HDAC4 0.0107 0.1059 0.3252
Echinococcus multilocularis histone deacetylase 7 0.0191 0.2 0.2611
Brugia malayi Bromodomain containing protein 0.0038 0.0272 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0129 0.0159
Schistosoma mansoni microtubule-associated protein tau 0.0687 0.7614 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0025 0.0129 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0025 0.0129 0.0159
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0138 0.0306
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0133 0.0139
Giardia lamblia Cathepsin B precursor 0.0025 0.0129 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0077 0.0059
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Plasmodium vivax histone deacetylase 2, putative 0.0191 0.2 0.6429
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0083 0.0781 0.1008
Leishmania major DNA polymerase eta, putative 0.002 0.0069 0.0136
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0025 0.0129 0.0159
Giardia lamblia Cathepsin L precursor 0.0025 0.0129 0.0159
Trypanosoma brucei beta tubulin 0.0023 0.01 0.0324
Brugia malayi Cathepsin L-like precursor 0.0081 0.0757 0.0741
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0069 0.0088
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Echinococcus granulosus peregrin 0.0038 0.0272 0.0302
Schistosoma mansoni hypothetical protein 0.0083 0.0781 0.0993
Echinococcus granulosus cysteine protease 0.0048 0.0384 0.0435
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0077 0.0072
Brugia malayi neuropeptide F receptor 0.0083 0.0781 0.0765
Schistosoma mansoni coup transcription factor 0.002 0.0077 0.0064
Giardia lamblia Cathepsin B precursor 0.0151 0.1549 0.3929
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0025 0.0129 0.0278
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.01 0.01
Loa Loa (eye worm) serotonin transporter b 0.0059 0.0507 0.0491
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Schistosoma mansoni neuropeptide receptor 0.0083 0.0781 0.0993
Brugia malayi ORL1-like opioid receptor 0.0083 0.0781 0.0765
Loa Loa (eye worm) hypothetical protein 0.0025 0.0129 0.0112
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0244 0.0284
Loa Loa (eye worm) neuropeptide F receptor 0.0083 0.0781 0.0765
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0112 0.0102
Echinococcus granulosus cathepsin l1 0.0058 0.0502 0.0575
Loa Loa (eye worm) hypothetical protein 0.0431 0.4719 0.471
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0489 0.1584
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.047 0.0598
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0069 0.0225
Entamoeba histolytica cysteine protease, putative 0.0048 0.0384 0.0835
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.047 0.0583
Brugia malayi Tachykinin-like peptides receptor 99D 0.0083 0.0781 0.0765
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0025 0.0129 0.0278
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0489 0.5
Leishmania major histone deacetylase, putative 0.0191 0.2 0.6449
Echinococcus multilocularis dro:myosuppressin receptor 0.0083 0.0781 0.1008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0112 0.0102
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0025 0.0129 0.0134
Trypanosoma cruzi cruzipain precursor, putative 0.0081 0.0757 0.1553
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0081 0.0757 0.1825
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0757 0.0741
Loa Loa (eye worm) hypothetical protein 0.0035 0.0244 0.0227
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0112 0.0102
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.047 0.0583
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0489 0.1114
Echinococcus granulosus 7tm_1 domain containing protein 0.0083 0.0781 0.0905
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0781 0.0905
Loa Loa (eye worm) melatonin receptor type 1A 0.0083 0.0781 0.0765
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.026 0.0594
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0077 0.008
Echinococcus multilocularis neuropeptides capa receptor 0.0083 0.0781 0.1008
Brugia malayi Cathepsin L-like precursor 0.0081 0.0757 0.0741
Echinococcus granulosus zinc finger protein 0.0022 0.0098 0.0097
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0069 0.0055
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0112 0.0095
Schistosoma mansoni zinc finger protein 0.0022 0.0098 0.0092
Trypanosoma brucei beta tubulin 0.0023 0.01 0.0324
Schistosoma mansoni importin beta-1 0.0028 0.0167 0.0183
Entamoeba histolytica hypothetical protein 0.0025 0.0129 0.0159
Echinococcus granulosus Tubulin beta 2C chain 0.0023 0.01 0.01
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0369 0.045
Loa Loa (eye worm) norepinephrine transporter 0.0059 0.0507 0.0491
Trypanosoma cruzi cysteine protease, putative 0.0048 0.0384 0.0758
Giardia lamblia Hypothetical protein 0.0025 0.0129 0.0159
Plasmodium vivax histone deacetylase, putative 0.0107 0.1059 0.3335
Leishmania major beta tubulin 0.0023 0.01 0.0236
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0112 0.0102
Onchocerca volvulus Cathepsin F homolog 0.0081 0.0757 0.2408
Onchocerca volvulus 0.0081 0.0757 0.2408
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0069 0.0052
Leishmania major cathepsin L-like protease 0.0081 0.0757 0.2383
Brugia malayi CXXC zinc finger family protein 0.0029 0.0179 0.0162
Echinococcus granulosus beta tubulin 0.0023 0.01 0.01
Onchocerca volvulus 0.0083 0.0781 0.2489
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0106 0.0097
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0112 0.0118
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.0765
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0083 0.0781 0.1008
Giardia lamblia Cathepsin L-like protease 0.0025 0.0129 0.0159
Schistosoma mansoni biogenic amine (5HT) receptor 0.0201 0.2114 0.275
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0757 0.1553
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.194 0.6265
Schistosoma mansoni biogenic amine (5HT) receptor 0.0083 0.0781 0.0993
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0489 0.1114
Plasmodium falciparum histone deacetylase 1 0.0287 0.3086 1
Echinococcus granulosus histone deacetylase 6 0.0191 0.2 0.2344
Loa Loa (eye worm) G-protein coupled receptor 0.0083 0.0781 0.0765
Giardia lamblia Cathepsin L precursor 0.0025 0.0129 0.0159
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0025 0.0129 0.0159
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0167 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0757 0.1825
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0129 0.0159
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0151 0.1549 0.3242
Plasmodium falciparum serine repeat antigen 3 0.0025 0.0129 0.0278
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0069 0.0225
Schistosoma mansoni cathepsin F (C01 family) 0.0081 0.0757 0.0961
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0169 0.176 0.2283
Brugia malayi histone deacetylase 11 0.0107 0.1059 0.1043
Onchocerca volvulus Histone deacetylase 10 homolog 0.0107 0.1059 0.3393
Echinococcus multilocularis serotonin transporter 0.0059 0.0507 0.0647
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0082 0.0115
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0112 0.0276
Onchocerca volvulus 0.0083 0.0781 0.2489
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0781 0.1008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0757 0.1825
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0757 0.2453
Echinococcus multilocularis Tubulin beta 2C chain 0.0023 0.01 0.0111
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0083 0.0781 0.0905
Brugia malayi GnHR receptor homolog 0.0083 0.0781 0.0765

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.7943 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 8.9125 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.