Detailed information for compound 1410828

Basic information

Technical information
  • TDR Targets ID: 1410828
  • Name: N-(2,3-dihydro-1,4-benzodioxin-7-yl)-2-quinaz olin-4-ylsulfanylacetamide
  • MW: 353.395 | Formula: C18H15N3O3S
  • H donors: 1 H acceptors: 3 LogP: 3 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc2c(c1)OCCO2)CSc1ncnc2c1cccc2
  • InChi: 1S/C18H15N3O3S/c22-17(21-12-5-6-15-16(9-12)24-8-7-23-15)10-25-18-13-3-1-2-4-14(13)19-11-20-18/h1-6,9,11H,7-8,10H2,(H,21,22)
  • InChiKey: YKODNCKXDVHLNF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2,3-dihydro-1,4-benzodioxin-7-yl)-2-quinazolin-4-ylsulfanyl-acetamide
  • N-(2,3-dihydro-1,4-benzodioxin-7-yl)-2-(4-quinazolinylthio)acetamide
  • N-(2,3-dihydro-1,4-benzodioxin-7-yl)-2-(quinazolin-4-ylthio)acetamide
  • N-(2,3-dihydro-1,4-benzodioxin-7-yl)-2-quinazolin-4-ylsulfanyl-ethanamide
  • ZINC03254330
  • SMR000385446
  • MLS001033035

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni tyrosine kinase 0.0437 0.352 0.3517
Echinococcus granulosus twitchin 0.0127 0.0755 0.0751
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0045 0.003 0.0026
Leishmania major protein kinase, putative 0.0081 0.0348 0.0293
Loa Loa (eye worm) hypothetical protein 0.0106 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0085 0.0386 0.0382
Echinococcus granulosus NDR protein kinase 0.0147 0.0936 0.0932
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0153 0.099 0.0986
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0936 0.0892
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0139 0.0867 0.0863
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0047 0.0048 0.0044
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0147 0.0936 0.0932
Echinococcus granulosus casein kinase i 0.0065 0.0209 0.0206
Loa Loa (eye worm) SRC-1 0.0162 0.107 0.1067
Loa Loa (eye worm) hypothetical protein 0.0048 0.0057 0.0053
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0162 0.107 0.1067
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.013 0.0788 0.0781
Loa Loa (eye worm) hypothetical protein 0.0156 0.1018 0.1014
Trichomonas vaginalis STE family protein kinase 0.0082 0.0361 0.0315
Trichomonas vaginalis STE family protein kinase 0.0058 0.0144 0.0097
Loa Loa (eye worm) TK protein kinase 0.0102 0.0536 0.0533
Loa Loa (eye worm) variant SH3 domain-containing protein 0.006 0.0163 0.016
Trypanosoma cruzi casein kinase, putative 0.0065 0.0209 0.0201
Loa Loa (eye worm) AUR protein kinase 0.0149 0.0956 0.0953
Trypanosoma brucei cdc2-related kinase 3 0.0119 0.0689 0.0637
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0081 0.0348 0.034
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0065 0.021 0.0206
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0643 0.0639
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0082 0.0361 0.0358
Schistosoma mansoni protein kinase 0.0058 0.0144 0.0141
Brugia malayi Temporarily assigned gene name protein 59 0.0145 0.092 0.0916
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0057 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0048 0.0044
Echinococcus multilocularis N chimaerin 0.0072 0.0267 0.0263
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0119 0.0689 0.2991
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0057 0.0053
Brugia malayi map kinase activated protein kinase protein 2 0.0429 0.3445 0.3442
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.008 0.0339 0.0284
Schistosoma mansoni tyrosine kinase 0.0071 0.0263 0.026
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0077 0.0316 0.0312
Schistosoma mansoni protein kinase 0.0234 0.1707 0.1703
Entamoeba histolytica casein kinase, putative 0.0065 0.0209 0.0154
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0135 0.0832 0.0828
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1254 0.1251
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0502 0.0457
Echinococcus granulosus protein kinase shaggy 0.013 0.0788 0.0785
Giardia lamblia Kinase, AGC PKA 0.0068 0.0231 0.0176
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.0209 0.0162
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0956 0.0913
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0187 0.1291 0.1287
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0048 0.0057 0.0053
Brugia malayi protein kinase C II. 0.0187 0.1291 0.1287
Toxoplasma gondii AGC kinase 0.0068 0.0231 0.0825
Brugia malayi Protein kinase domain containing protein 0.0147 0.0936 0.0932
Brugia malayi Protein kinase domain containing protein 0.0069 0.0245 0.0241
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0045 0.0026 0.0022
Entamoeba histolytica protein kinase, putative 0.0064 0.0199 0.0144
Schistosoma mansoni protein kinase 0.0082 0.0361 0.0358
Echinococcus multilocularis casein kinase I alpha 0.0065 0.0209 0.0206
Loa Loa (eye worm) hypothetical protein 0.0088 0.041 0.0406
Toxoplasma gondii casein kinase I 0.0065 0.0209 0.0722
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0211 0.1509 0.1506
Brugia malayi Protein kinase domain containing protein 0.0069 0.0245 0.0241
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0502 0.0457
Brugia malayi Protein kinase domain containing protein 0.0211 0.1509 0.1506
Echinococcus granulosus insulin receptor 0.0489 0.3976 0.3974
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0442 0.0439
Echinococcus granulosus serine/threonine protein kinase 0.0168 0.1123 0.1119
Onchocerca volvulus 0.0065 0.0209 0.0201
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0106 0.0569 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.2145 0.2142
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0151 0.0095
Brugia malayi Variant SH3 domain containing protein 0.006 0.0163 0.016
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0098 0.0502 0.0499
Schistosoma mansoni tyrosine kinase 0.0269 0.2025 0.2022
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0316 0.027
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0202 0.1429 0.1426
Echinococcus granulosus NCK adaptor protein 0.006 0.0163 0.016
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2228 0.2191
Echinococcus granulosus c-Jun N-terminal kinases 0.0283 0.2145 0.2142
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0162 0.1068 0.1064
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0147 0.0936 0.0932
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1166 1 1
Entamoeba histolytica protein kinase, putative 0.0123 0.0724 0.0671
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0156 0.1021 0.1017
Onchocerca volvulus 0.013 0.0788 0.0781
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0165 0.1093 0.1086
Schistosoma mansoni serine/threonine kinase 0.0147 0.0936 0.0932
Echinococcus multilocularis tyrosine protein kinase shark 0.0069 0.0245 0.0241
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0068 0.0231 0.0223
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.013 0.0788 0.3457
Brugia malayi Protein kinase domain containing protein 0.0077 0.0316 0.0312
Echinococcus multilocularis protein kinase shaggy 0.013 0.0788 0.0785
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0502 0.0457
Leishmania major casein kinase, putative 0.0065 0.0209 0.0154
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0149 0.0956 0.8956
Trichomonas vaginalis CAMK family protein kinase 0.1166 1 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0286 0.0231
Schistosoma mansoni protein kinase 0.0082 0.0361 0.0358
Loa Loa (eye worm) TK/ABL protein kinase 0.0303 0.232 0.2317
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0788 0.0736
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0139 0.0863 0.3811
Brugia malayi serine/threonine-protein kinase PAK 7 0.0247 0.1823 0.182
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0242 0.1777 0.1774
Loa Loa (eye worm) hypothetical protein 0.013 0.0788 0.0785
Toxoplasma gondii CMGC kinase, CK2 family 0.0098 0.0502 0.2107
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0069 0.024 0.0236
Entamoeba histolytica protein kinase, putative 0.0286 0.2173 0.2128
Echinococcus granulosus fibroblast growth factor receptor 4 0.0259 0.1933 0.193
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0643 0.0598
Loa Loa (eye worm) AUR protein kinase 0.0149 0.0956 0.0953
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2228 0.2191
Plasmodium falciparum protein kinase, putative 0.0059 0.0151 0.0934
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0689 0.0686
Echinococcus granulosus calcium activated potassium channel 0.0091 0.0442 0.0439
Plasmodium falciparum glycogen synthase kinase 3 0.013 0.0788 0.7235
Schistosoma mansoni protein kinase 0.0059 0.0151 0.0147
Echinococcus multilocularis casein kinase I alpha 0.0065 0.0209 0.0206
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0119 0.0689 0.0686
Brugia malayi intracellular kinase 0.013 0.0788 0.0785
Plasmodium falciparum protein kinase 5 0.0119 0.0689 0.6259
Trypanosoma cruzi aurora B kinase, putative 0.0149 0.0956 0.0949
Loa Loa (eye worm) AGC/AKT protein kinase 0.0292 0.2228 0.2225
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0643 0.0639
Giardia lamblia Kinase, CMGC CK2 0.0098 0.0502 0.0448
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0211 0.1509 0.1506
Brugia malayi Protein kinase domain containing protein 0.0195 0.1363 0.136
Echinococcus multilocularis mitogen activated protein kinase 0.008 0.0339 0.0335
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0956 0.0905
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0231 0.1687 0.1684
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0788 0.0744
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Echinococcus granulosus activin receptor type 0.0059 0.0151 0.0147
Entamoeba histolytica serine/threonine protein kinase, putative 0.1166 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0057 0.0053
Brugia malayi protein kinase C3,putative 0.0154 0.1002 0.0999
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0153 0.099 0.0986
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0077 0.0316 0.0312
Brugia malayi STE20-like kinase MST 0.0274 0.207 0.2067
Echinococcus granulosus ephrin type A receptor 4 A 0.0108 0.059 0.0587
Echinococcus multilocularis hypothetical protein 0.0069 0.0241 0.0237
Plasmodium vivax protein kinase Crk2 0.0119 0.0689 0.6457
Onchocerca volvulus Serine\/threonine kinase homolog 0.1166 1 1
Onchocerca volvulus 0.0069 0.0245 0.0237
Brugia malayi Kinase associated domain 1 family protein 0.0069 0.0241 0.0237
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0048 0.0057 0.0053
Echinococcus multilocularis rac serine:threonine kinase 0.0168 0.1123 0.1119
Brugia malayi Protein kinase domain containing protein 0.1045 0.8924 0.8924
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0022 0.0018
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0246 0.1818 0.1815
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.008 0.0339 0.0331
Schistosoma mansoni vav2 0.0078 0.0322 0.0318
Loa Loa (eye worm) hypothetical protein 0.0048 0.0057 0.0053
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0161 0.1063 0.106
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0139 0.0867 0.0863
Brugia malayi P38 map kinase family protein 2 0.0165 0.1093 0.1089
Echinococcus granulosus raf serine:threonine protein kinase 0.0075 0.0292 0.0288
Echinococcus granulosus protein kinase c epsilon type 0.0187 0.1291 0.1287
Echinococcus granulosus casein kinase I alpha 0.0065 0.0209 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0766 0.0763
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0689 0.0637
Leishmania major protein kinase A catalytic subunit 0.0068 0.0231 0.0176
Echinococcus multilocularis tyrosine protein kinase Blk 0.0135 0.0832 0.0828
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0068 0.0231 0.0223
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0162 0.107 0.1067
Entamoeba histolytica protein kinase domain containing protein 0.0123 0.0724 0.0671
Brugia malayi Protein kinase domain containing protein 0.0489 0.3976 0.3974
Plasmodium falciparum serine/threonine protein kinase, putative 0.0149 0.0956 0.8898
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0065 0.021 0.0206
Plasmodium vivax glycogen synthase kinase 3, putative 0.013 0.0788 0.7381
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0303 0.232 0.2317
Schistosoma mansoni tyrosine kinase 0.0259 0.1933 0.193
Echinococcus multilocularis epidermal growth factor receptor 0.0437 0.352 0.3517
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0231 0.0227
Leishmania major protein kinase, putative 0.0048 0.0057 0.0001
Schistosoma mansoni growth factor receptor-bound protein 0.006 0.0163 0.016
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0162 0.107 0.1067
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.21 0.2097
Echinococcus multilocularis cyclin dependent kinase 0.0119 0.0689 0.0686
Brugia malayi Protein kinase domain containing protein 0.0123 0.0724 0.072
Schistosoma mansoni protein kinase 0.0048 0.0057 0.0053
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0048 0.0057 0.0534
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1166 1 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0162 0.107 0.1067
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0231 0.0227
Schistosoma mansoni serine/threonine-protein kinase 0.0168 0.1123 0.1119
Brugia malayi Protein kinase domain containing protein 0.0091 0.0442 0.0439
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0316 0.027
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0165 0.1093 0.1042
Loa Loa (eye worm) hypothetical protein 0.0069 0.0245 0.0241
Brugia malayi Protein kinase domain containing protein 0.0114 0.0643 0.0639
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0502 0.0457
Brugia malayi Protein kinase domain containing protein 0.0292 0.2228 0.2225
Echinococcus multilocularis nervana 2 0.0139 0.0867 0.0863
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0156 0.1021 0.1017
Echinococcus multilocularis rho associated protein kinase 0.0351 0.2754 0.2751
Echinococcus multilocularis mitogen activated protein kinase 3 0.008 0.0339 0.0335
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0231 0.0227
Loa Loa (eye worm) AGC/NDR protein kinase 0.0147 0.0936 0.0932
Loa Loa (eye worm) hypothetical protein 0.0134 0.0819 0.0816
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0689 0.0682
Echinococcus granulosus RNA directed DNA polymerase 0.0045 0.0026 0.0022
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0259 0.1933 0.193
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0123 0.0724 0.0716
Echinococcus multilocularis raf serine:threonine protein kinase 0.0075 0.0292 0.0288
Trichomonas vaginalis STE family protein kinase 0.0082 0.0361 0.0315
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0689 0.0686
Onchocerca volvulus 0.0069 0.0245 0.0237
Giardia lamblia Aurora kinase 0.0149 0.0956 0.0905
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2228 0.2191
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Echinococcus multilocularis tyrosine protein kinase HCK 0.0102 0.0536 0.0533
Echinococcus multilocularis epidermal growth factor receptor 0.0672 0.5602 0.5601
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0048 0.0057 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.1166 1 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0688 0.5749 0.5747
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.1777 0.1774
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0202 0.1429 0.1426
Schistosoma mansoni tyrosine kinase 0.0162 0.107 0.1067
Loa Loa (eye worm) TK/EPH protein kinase 0.0128 0.0766 0.0762
Loa Loa (eye worm) hypothetical protein 0.006 0.0163 0.016
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0156 0.1021 0.1017
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0096 0.0484 0.048
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0068 0.0231 0.0825
Echinococcus granulosus titin 0.0044 0.0022 0.0018
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1045 0.8924 0.8924
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0259 0.1933 0.193
Loa Loa (eye worm) hypothetical protein 0.0156 0.1018 0.1014
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0065 0.0205 0.0201
Giardia lamblia Kinase, CMGC GSK 0.013 0.0788 0.0736
Trichomonas vaginalis STE family protein kinase 0.0081 0.0348 0.0302
Onchocerca volvulus 0.0069 0.0245 0.0237
Echinococcus granulosus epidermal growth factor receptor 0.0437 0.352 0.3517
Trypanosoma brucei casein kinase I, isoform 2 0.0065 0.0209 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1687 0.1684
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0689 0.0637
Brugia malayi Protein kinase domain containing protein 0.0147 0.0936 0.0932
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0183 0.1254 0.1251
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0123 0.0727 0.0674
Echinococcus granulosus Protein kinase C brain isozyme 0.0231 0.1687 0.1684
Loa Loa (eye worm) CMGC/GSK protein kinase 0.013 0.0788 0.0785
Loa Loa (eye worm) AGC/PKA protein kinase 0.0068 0.0231 0.0227
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0502 0.0499
Schistosoma mansoni protein kinase 0.0234 0.1707 0.1703
Loa Loa (eye worm) hypothetical protein 0.0085 0.0386 0.0382
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.008 0.0339 0.0335
Giardia lamblia Kinase, CMGC MAPK 0.008 0.0339 0.0284
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0123 0.0724 0.0671
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0242 0.1777 0.1774
Trypanosoma cruzi casein kinase II, putative 0.0098 0.0502 0.0495
Loa Loa (eye worm) hypothetical protein 0.0303 0.2324 0.2321
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0183 0.1254 0.1251
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0492 0.4 0.3998
Entamoeba histolytica protein kinase, putative 0.0056 0.0126 0.007
Schistosoma mansoni tyrosine kinase 0.0075 0.03 0.0296
Echinococcus multilocularis roundabout 2 0.0127 0.076 0.0757
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0068 0.0231 0.0227
Loa Loa (eye worm) sex muscle abnormal protein 5 0.006 0.0163 0.016
Echinococcus multilocularis PAK box P21 Rho binding 0.0058 0.0144 0.0141
Echinococcus multilocularis tyrosine protein kinase Abl 0.0185 0.1277 0.1274
Schistosoma mansoni protein kinase 0.0065 0.0209 0.0206
Brugia malayi Protein kinase domain containing protein 0.0198 0.1386 0.1383
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0231 0.0227
Loa Loa (eye worm) hypothetical protein 0.0045 0.0027 0.0023
Toxoplasma gondii AGC kinase 0.0068 0.0231 0.0825
Echinococcus multilocularis casein kinase i 0.0065 0.0209 0.0206
Echinococcus granulosus neuroglian 0.0104 0.0553 0.055
Trypanosoma brucei aurora B kinase 0.0149 0.0956 0.0905
Trypanosoma brucei rac serine-threonine kinase, putative 0.0292 0.2228 0.2184
Echinococcus multilocularis myotubularin protein 13 0.0045 0.0027 0.0023
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0429 0.3445 0.3442
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0148 0.095 0.0946
Loa Loa (eye worm) TK/ALK protein kinase 0.0302 0.2316 0.2313
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0119 0.0689 0.0637
Brugia malayi Pleckstrin Homology Domain 0.0045 0.0027 0.0023
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.013 0.0788 0.0785
Echinococcus granulosus tyrosine protein kinase Src64B 0.0162 0.107 0.1067
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0077 0.0316 0.0312
Brugia malayi phosphoinositide-dependent protein kinase I 0.0077 0.0316 0.0312
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0259 0.1933 0.193
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0247 0.1823 0.182
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0286 0.2173 0.217
Echinococcus granulosus casein kinase ii subunit alpha 0.0098 0.0502 0.0499
Loa Loa (eye worm) hypothetical protein 0.0092 0.0446 0.0442
Echinococcus granulosus cyclin dependent kinase 0.0119 0.0689 0.0686
Brugia malayi Tyrosine-protein kinase abl-1 0.0185 0.1277 0.1274
Echinococcus multilocularis tyrosine kinase 0.0069 0.0245 0.0241
Schistosoma mansoni adapter molecule crk 0.006 0.0163 0.016
Schistosoma mansoni tyrosine kinase 0.0401 0.3199 0.3197
Entamoeba histolytica PH domain containing protein kinase, putative 0.0074 0.0286 0.0231
Echinococcus multilocularis 0.0195 0.1367 0.1363
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0123 0.0724 0.072
Echinococcus multilocularis nervana 2 0.0139 0.0867 0.0863
Brugia malayi cell division control protein 2 homolog 0.0119 0.0689 0.0686
Plasmodium falciparum casein kinase 1 0.0065 0.0209 0.1511
Brugia malayi SRC-1 0.0162 0.107 0.1067
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.008 0.0339 0.0331
Brugia malayi Protein kinase domain containing protein 0.0119 0.0689 0.0686
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0048 0.0057 0.0053
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0234 0.1707 0.1703
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Echinococcus granulosus tyrosine kinase 0.0135 0.0832 0.0828
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0048 0.0057 0.0534
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0081 0.0348 0.034
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0437 0.352 0.3517
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0047 0.0048 0.0044
Echinococcus multilocularis serine:threonine protein kinase N2 0.0147 0.0936 0.0932
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0059 0.0151 0.0143
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0165 0.1093 0.1086
Echinococcus granulosus epidermal growth factor receptor 0.0672 0.5602 0.5601
Echinococcus granulosus serine threonine protein kinase nrc 0.0162 0.1068 0.1064
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1166 1 1
Onchocerca volvulus 0.0069 0.0245 0.0237
Onchocerca volvulus 0.0329 0.2552 0.2546
Entamoeba histolytica PH domain containing protein kinase, putative 0.0168 0.1123 0.1072
Trichomonas vaginalis AGC family protein kinase 0.0077 0.0316 0.027
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0202 0.1429 0.1426
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0202 0.1429 0.1426
Echinococcus granulosus defective proboscis extension response 0.0085 0.0386 0.0382
Echinococcus granulosus tyrosine kinase 0.0069 0.0245 0.0241
Entamoeba histolytica PH domain containing protein kinase, putative 0.0168 0.1123 0.1072
Brugia malayi casein kinase I 0.0065 0.0209 0.0206
Brugia malayi Sex muscle abnormal protein 5 0.006 0.0163 0.016
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0231 0.0227
Echinococcus multilocularis Immunoglobulin 0.0085 0.0386 0.0382
Echinococcus granulosus titin 0.0044 0.0022 0.0018
Onchocerca volvulus 0.0069 0.0245 0.0237
Trypanosoma brucei protein kinase, putative 0.008 0.0339 0.0284
Leishmania major protein kinase A catalytic subunit isoform 1 0.0068 0.0231 0.0176
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.0209 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Leishmania major casein kinase II, putative 0.0098 0.0502 0.0448
Plasmodium falciparum NIMA related kinase 1 0.0139 0.0863 0.7974
Loa Loa (eye worm) hypothetical protein 0.0125 0.0743 0.0739
Toxoplasma gondii aurora kinase 0.0149 0.0956 0.4252
Echinococcus granulosus nervana 2 0.0139 0.0867 0.0863
Echinococcus multilocularis mitogen activated protein kinase 14 0.0165 0.1093 0.1089
Plasmodium falciparum calcium-dependent protein kinase 3 0.0048 0.0057 0.0005
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0149 0.0956 0.0905
Loa Loa (eye worm) hypothetical protein 0.01 0.0523 0.0519
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0202 0.1429 0.1426
Brugia malayi Protein kinase domain containing protein 0.0069 0.0245 0.0241
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0081 0.0348 0.0293
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Leishmania major protein kinase A catalytic subunit isoform 2 0.0068 0.0231 0.0176
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0863 0.0819
Entamoeba histolytica protein kinase, putative 0.013 0.0788 0.0736
Schistosoma mansoni kinase 0.0754 0.6339 0.6337
Echinococcus granulosus Immunoglobulin 0.0085 0.0386 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.021 0.0206
Trypanosoma cruzi casein kinase, putative 0.0065 0.0209 0.0201
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0081 0.0348 0.0293
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0059 0.0151 0.0446
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0077 0.0316 0.0312
Echinococcus multilocularis RNA directed DNA polymerase 0.0045 0.0026 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0689 0.0682
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0689 0.0682
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0082 0.0361 0.0358
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0162 0.107 0.1067
Echinococcus granulosus tyrosine protein kinase Fyn 0.0162 0.107 0.1067
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0165 0.1093 0.1042
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0162 0.107 0.1067
Echinococcus multilocularis c src tyrosine kinase 0.0096 0.0484 0.048
Loa Loa (eye worm) hypothetical protein 0.0088 0.041 0.0406
Loa Loa (eye worm) AGC/PKA protein kinase 0.0068 0.0231 0.0227
Loa Loa (eye worm) AGC/PKN protein kinase 0.0147 0.0936 0.0932
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0162 0.107 0.1067
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0082 0.0361 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Echinococcus multilocularis growth factor receptor bound protein 2 0.006 0.0163 0.016
Echinococcus granulosus serine:threonine kinase SAD 1 0.0048 0.0057 0.0053
Loa Loa (eye worm) hypothetical protein 0.0195 0.136 0.1357
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0048 0.0057 0.0049
Brugia malayi casein kinase 1, delta 0.0065 0.0209 0.0206
Entamoeba histolytica protein kinase, putative 0.0149 0.0956 0.0905
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0065 0.021 0.0206
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Onchocerca volvulus 0.0351 0.2754 0.2748
Echinococcus multilocularis serine threonine protein kinase 0.0193 0.1345 0.1342
Giardia lamblia Kinase, AGC AKT 0.0117 0.0672 0.0619
Echinococcus granulosus rho-associated protein kinase 1 0.0351 0.2754 0.2751
Loa Loa (eye worm) hypothetical protein 0.0124 0.0736 0.0733
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0068 0.0231 0.0176
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0119 0.0689 0.0686
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0098 0.0502 0.4705
Echinococcus granulosus roundabout 2 0.0127 0.076 0.0757
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0072 0.0267 0.0263
Brugia malayi Fibronectin type III domain containing protein 0.0088 0.041 0.0406
Trichomonas vaginalis CAMK family protein kinase 0.1166 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0098 0.0502 0.0448
Brugia malayi Protein kinase domain containing protein 0.0202 0.1429 0.1426
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0048 0.0057 0.0002
Loa Loa (eye worm) hypothetical protein 0.0162 0.1066 0.1062
Echinococcus multilocularis calcium activated potassium channel 0.0091 0.0442 0.0439
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0165 0.1093 0.1089
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1129 0.9669 0.9668
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0048 0.0057 0.0053
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0069 0.0245 0.019
Trypanosoma cruzi polo-like protein kinase, putative 0.1166 1 1
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0068 0.0231 0.0176
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0044 0.0022 0.0018
Echinococcus granulosus mitogen activated protein kinase 3 0.008 0.0339 0.0335
Trichomonas vaginalis CAMK family protein kinase 0.056 0.4611 0.4585
Entamoeba histolytica protein kinase , putative 0.0149 0.0956 0.0905
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0068 0.0231 0.0223
Echinococcus granulosus Glutaredoxin protein 5 0.0139 0.0867 0.0863
Trypanosoma cruzi casein kinase, putative 0.0065 0.0209 0.0201
Brugia malayi C1-like domain containing protein 0.0153 0.099 0.0986
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0689 0.0682
Leishmania major protein kinase, putative 0.0149 0.0956 0.0905
Echinococcus granulosus c src tyrosine kinase 0.0096 0.0484 0.048
Brugia malayi hypothetical protein 0.0088 0.041 0.0406
Loa Loa (eye worm) hypothetical protein 0.0234 0.1712 0.1709
Brugia malayi Variant SH3 domain containing protein 0.006 0.0163 0.016
Entamoeba histolytica protein kinase, putative 0.0292 0.2228 0.2184
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2228 0.2191
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Loa Loa (eye worm) hypothetical protein 0.0092 0.0446 0.0442
Echinococcus multilocularis ephrin type A receptor 4 A 0.0108 0.059 0.0587
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0048 0.0057 0.0002
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0048 0.0057 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.056 0.4611 0.4585
Echinococcus multilocularis mitogen activated protein kinase 14 0.0165 0.1093 0.1089
Echinococcus granulosus tyrosine protein kinase Lyn 0.0185 0.1272 0.1268
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0099 0.0511 0.0508
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0156 0.1021 0.1017
Echinococcus granulosus casein kinase I delta 0.0065 0.0209 0.0206
Brugia malayi Protein kinase domain containing protein 0.0302 0.2317 0.2314
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0128 0.0766 0.0763
Schistosoma mansoni hypothetical protein 0.0069 0.0241 0.0237
Brugia malayi serine/threonine-protein kinase 6 0.0149 0.0956 0.0953
Schistosoma mansoni atypical protein kinase C 0.0286 0.2168 0.2165
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0117 0.0672 0.0669
Loa Loa (eye worm) hypothetical protein 0.0114 0.0643 0.0639
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.006 0.0163 0.016
Loa Loa (eye worm) hypothetical protein 0.0069 0.0241 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.3445 0.3442
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0689 0.0686
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0147 0.0936 0.0932
Brugia malayi p70 ribosomal S6 kinase beta 0.0286 0.2173 0.217
Schistosoma mansoni tyrosine kinase 0.0672 0.5602 0.5601
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0045 0.003 0.0026
Onchocerca volvulus 0.0137 0.0843 0.0836
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0123 0.0724 0.0671
Schistosoma mansoni serine/threonine-protein kinase 0.0168 0.1123 0.1119
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0162 0.107 0.1067
Onchocerca volvulus 0.013 0.0788 0.0781
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0956 0.0913
Loa Loa (eye worm) hypothetical protein 0.006 0.016 0.0156
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0072 0.0267 0.0263
Brugia malayi SH2 domain containing protein 0.0069 0.0245 0.0241
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0162 0.107 0.1067
Plasmodium vivax casein kinase 1, putative 0.0065 0.0209 0.196
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0069 0.0245 0.0241
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.013 0.0788 0.0785
Brugia malayi Hr1 repeat family protein 0.0147 0.0936 0.0932
Schistosoma mansoni tyrosine kinase 0.0401 0.3199 0.3197
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0162 0.1068 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.008 0.0339 0.0331
Echinococcus granulosus mitogen activated protein kinase 11 0.0165 0.1093 0.1089
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0149 0.0956 0.0905
Loa Loa (eye worm) hypothetical protein 0.0097 0.0488 0.0484
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0069 0.0245 0.0241
Schistosoma mansoni tyrosine kinase 0.0096 0.0484 0.048
Plasmodium vivax calcium-dependent protein kinase, putative 0.0048 0.0057 0.0534
Echinococcus multilocularis NCK adaptor protein 0.006 0.0163 0.016
Echinococcus multilocularis aurora kinase A 0.0149 0.0956 0.0953
Echinococcus multilocularis Immunoglobulin 0.0085 0.0386 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.1429 0.1426
Entamoeba histolytica p21-activated kinase 0.0089 0.0416 0.0362
Onchocerca volvulus Tyrosine kinase homolog 0.0601 0.4976 0.4972
Onchocerca volvulus 0.0546 0.4489 0.4484
Echinococcus granulosus nervana 2 0.0139 0.0867 0.0863
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0442 0.0439
Schistosoma mansoni tyrosine kinase 0.0096 0.0484 0.048
Entamoeba histolytica protein kinase, putative 0.005 0.007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0072 0.027 0.0266
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0956 0.0913
Echinococcus granulosus casein kinase I delta 0.0065 0.0209 0.0206
Echinococcus granulosus protein kinase C gamma type 0.0193 0.1345 0.1342
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0689 0.0637
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0339 0.0292
Brugia malayi Variant SH3 domain containing protein 0.0072 0.0267 0.0263
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0048 0.0057 0.0053
Echinococcus granulosus tyrosine protein kinase ABL1 0.0303 0.232 0.2317
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0183 0.1254 0.1251
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0724 0.072
Brugia malayi MAP kinase sur-1 0.008 0.0339 0.0335
Schistosoma mansoni growth factor receptor-bound protein 0.006 0.0163 0.016
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0149 0.0956 0.0953
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0068 0.0231 0.2165
Entamoeba histolytica protein kinase 2, putative 0.0162 0.1068 0.1017
Schistosoma mansoni protein kinase 0.0149 0.0956 0.0953
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.2754 0.2751
Loa Loa (eye worm) CMGC/GSK protein kinase 0.013 0.0788 0.0785
Entamoeba histolytica protein kinase, putative 0.0065 0.021 0.0154
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0234 0.1707 0.1703
Brugia malayi Casein kinase II, alpha chain 0.0098 0.0502 0.0499
Loa Loa (eye worm) hypothetical protein 0.0137 0.0843 0.084
Brugia malayi Stress-activated protein kinase jnk-1 0.0283 0.2145 0.2142
Brugia malayi protein-tyrosine kinase 0.0135 0.0832 0.0828
Entamoeba histolytica protein kinase, putative 0.0065 0.021 0.0154
Loa Loa (eye worm) hypothetical protein 0.0085 0.0388 0.0384
Schistosoma mansoni cell adhesion molecule 0.0108 0.0593 0.059
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0936 0.0932
Trypanosoma brucei protein kinase, putative 0.013 0.0788 0.0736
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2228 0.2191
Echinococcus multilocularis cyclin dependent kinase 5 0.0119 0.0689 0.0686
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0082 0.0361 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Trypanosoma brucei polo-like protein kinase 0.1166 1 1
Trypanosoma brucei cdc2-related kinase 1 0.0119 0.0689 0.0637
Echinococcus granulosus mitogen activated protein kinase 0.008 0.0339 0.0335
Echinococcus granulosus tyrosine protein kinase Src42A 0.0099 0.0511 0.0508
Brugia malayi Protein kinase domain containing protein 0.0069 0.0245 0.0241
Giardia lamblia Kinase, AGC PKA 0.0162 0.1068 0.1017
Leishmania major protein kinase, putative 0.0059 0.0151 0.0095
Giardia lamblia Kinase, CMGC GSK 0.013 0.0788 0.0736
Echinococcus multilocularis death associated protein kinase 1 0.094 0.7988 0.7987
Entamoeba histolytica protein kinase, putative 0.0149 0.0956 0.0905
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0128 0.0766 0.0763
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0347 0.2711 0.2708
Brugia malayi Tyrosine-protein kinase abl-1 0.0144 0.0911 0.0907
Echinococcus multilocularis tyrosine protein kinase Srms 0.0135 0.0832 0.0828
Onchocerca volvulus 0.0092 0.0446 0.0438
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0139 0.0863 0.8081
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.0022 0.0018
Echinococcus multilocularis serine:threonine protein kinase 3 0.0274 0.207 0.2067
Brugia malayi putative serine/threonine kinase SADA gamma 0.0048 0.0057 0.0053
Loa Loa (eye worm) hypothetical protein 0.0156 0.1018 0.1014
Trypanosoma cruzi polo-like protein kinase, putative 0.1166 1 1
Schistosoma mansoni tyrosine kinase 0.0437 0.352 0.3517
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0065 0.021 0.0206
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0124 0.0734 0.069
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0274 0.207 0.2067
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0429 0.3445 0.3442
Trypanosoma cruzi Protein kinase B 0.0168 0.1123 0.1116
Echinococcus multilocularis serine:threonine protein kinase 38 0.0147 0.0936 0.0932
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0148 0.095 0.0946
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0689 0.0645
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0283 0.2145 0.2142
Schistosoma mansoni ephrin receptor 0.0108 0.059 0.0587
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Brugia malayi serine/threonine kinase 12 0.0149 0.0956 0.0953
Giardia lamblia Kinase, CK1 Casein kinase 0.0065 0.0209 0.0154
Schistosoma mansoni nck2/grb4 0.006 0.0163 0.016
Echinococcus granulosus protein kinase c iota type 0.0279 0.2107 0.2104
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0231 0.0227
Loa Loa (eye worm) TK/EGFR protein kinase 0.0672 0.5602 0.5601
Echinococcus granulosus mitogen activated protein kinase 14 0.0165 0.1093 0.1089
Echinococcus granulosus serine:threonine protein kinase N2 0.0147 0.0936 0.0932
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2228 0.2191
Echinococcus multilocularis activin receptor type 0.0059 0.0151 0.0147
Loa Loa (eye worm) CAMK protein kinase 0.0044 0.0022 0.0018
Trichomonas vaginalis AGC family protein kinase 0.0153 0.0991 0.0948
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0114 0.0647 0.0644
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0149 0.0956 0.0953
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0788 0.0744
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.008 0.0339 0.0284
Onchocerca volvulus 0.0156 0.1018 0.1011
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0059 0.0151 0.0095
Echinococcus granulosus tyrosine protein kinase shark 0.0069 0.0245 0.0241
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0114 0.0643 0.0639
Schistosoma mansoni nephrin 0.0107 0.0577 0.0574
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0059 0.0151 0.0143
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0085 0.0386 0.0382
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0147 0.0936 0.0932
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0048 0.0057 0.0053
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0072 0.0267 0.0263
Plasmodium vivax unspecified product 0.0098 0.0502 0.4705
Entamoeba histolytica protein kinase, putative 0.0147 0.0936 0.0884
Echinococcus multilocularis protein kinase c iota type 0.0279 0.2107 0.2104
Trichomonas vaginalis AGC family protein kinase 0.0292 0.2228 0.2191
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0048 0.0057 0.0053
Entamoeba histolytica protein kinase, putative 0.0123 0.0724 0.0671
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0072 0.0267 0.0263
Brugia malayi Immunoglobulin I-set domain containing protein 0.0088 0.041 0.0406
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0766 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.1291 0.1287
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0689 0.0645
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1166 1 1
Echinococcus granulosus cyclin dependent kinase 5 0.0119 0.0689 0.0686
Brugia malayi protein unc-22 0.0044 0.0022 0.0018
Schistosoma mansoni serine/threonine kinase 0.0091 0.0442 0.0439
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Echinococcus multilocularis casein kinase I alpha 0.0065 0.0209 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1254 0.1251
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0072 0.0267 0.0263
Trichomonas vaginalis CK1 family protein kinase 0.0065 0.0209 0.0162
Loa Loa (eye worm) TK/ROR protein kinase 0.0055 0.0117 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0048 0.0044
Brugia malayi Immunoglobulin I-set domain containing protein 0.0688 0.5749 0.5747
Brugia malayi hypothetical protein 0.0069 0.0245 0.0241
Trypanosoma cruzi casein kinase, putative 0.0065 0.0209 0.0201
Echinococcus granulosus casein kinase I alpha 0.0065 0.0209 0.0206
Schistosoma mansoni vesicular amine transporter 0.0085 0.0386 0.0382
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0123 0.0724 0.0716
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0339 0.0335
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0689 0.0645
Entamoeba histolytica protein kinase, putative 0.0292 0.2228 0.2184
Entamoeba histolytica hypothetical protein 0.0123 0.0724 0.0671
Echinococcus granulosus casein kinase I alpha 0.0065 0.0209 0.0206
Onchocerca volvulus 0.0069 0.0245 0.0237
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0055 0.0117 0.0113
Echinococcus multilocularis myosin iiia 0.0081 0.0348 0.0344
Echinococcus granulosus dual specificity 0.0123 0.0724 0.072
Entamoeba histolytica protein kinase domain containing protein 0.013 0.0788 0.0736
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0231 0.0184
Brugia malayi Protein kinase c protein 2 0.0107 0.0582 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0057 0.0053
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.008 0.0339 0.1333
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Echinococcus granulosus tyrosine protein kinase Srms 0.0069 0.0245 0.0241
Loa Loa (eye worm) hypothetical protein 0.0124 0.0736 0.0733
Brugia malayi Furin-like cysteine rich region family protein 0.0672 0.5602 0.5601
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0048 0.0057 0.0053
Entamoeba histolytica protein kinase, putative 0.0102 0.0536 0.0483
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0068 0.0231 0.1727
Schistosoma mansoni tyrosine kinase 0.0489 0.3976 0.3974
Echinococcus multilocularis titin 0.0044 0.0022 0.0018
Echinococcus granulosus tyrosine protein kinase Blk 0.0135 0.0832 0.0828
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0162 0.1068 1
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0283 0.2145 0.2142
Toxoplasma gondii AGC kinase 0.0286 0.2173 1
Echinococcus granulosus glycogen synthase kinase 3 beta 0.013 0.0788 0.0785
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0689 0.0637
Trypanosoma brucei protein kinase, putative 0.0059 0.0151 0.0095
Loa Loa (eye worm) AUR protein kinase 0.0149 0.0956 0.0953
Echinococcus granulosus N chimaerin 0.0072 0.0267 0.0263
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Echinococcus multilocularis mitogen activated protein kinase 11 0.0165 0.1093 0.1089
Schistosoma mansoni hypothetical protein 0.0069 0.0241 0.0237
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0149 0.0956 0.0905
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0429 0.3445 0.3442
Echinococcus multilocularis casein kinase I delta 0.0065 0.0209 0.0206
Plasmodium falciparum calcium-dependent protein kinase 4 0.0048 0.0057 0.0005
Plasmodium falciparum calcium-dependent protein kinase 2 0.0048 0.0057 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0339 0.0292
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0048 0.0057 0.0053
Schistosoma mansoni tyrosine kinase 0.0162 0.107 0.1067
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0057 0.0009
Trichomonas vaginalis STE family protein kinase 0.0139 0.0863 0.0819
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0442 0.0439
Entamoeba histolytica casein kinase, putative 0.0098 0.0502 0.0448
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0202 0.1429 0.1423
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0048 0.0057 0.0001
Echinococcus granulosus growth factor receptor bound protein 2 0.006 0.0163 0.016
Loa Loa (eye worm) hypothetical protein 0.0088 0.041 0.0406
Giardia lamblia Kinase, STE STE20 0.0081 0.0348 0.0293
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0068 0.0231 0.0227
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0162 0.1068 0.1064
Schistosoma mansoni titin 0.0044 0.0022 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0956 0.0953
Trypanosoma cruzi casein kinase, putative 0.0065 0.0209 0.0201
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0065 0.0209 0.0206
Plasmodium falciparum casein kinase 2, alpha subunit 0.0098 0.0502 0.4409
Entamoeba histolytica casein kinase 1, putative 0.0065 0.0209 0.0154
Schistosoma mansoni ste20-related kinase 0.0216 0.1553 0.155
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0048 0.0057 0.0529
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0936 0.0932
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0502 0.0457
Schistosoma mansoni protein kinase 0.0048 0.0057 0.0053
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0242 0.1777 0.1774
Schistosoma mansoni tyrosine kinase 0.0489 0.3976 0.3974
Brugia malayi ephrin receptor 1 precursor 0.007 0.0252 0.0248
Trichomonas vaginalis CAMK family protein kinase 0.1166 1 1
Entamoeba histolytica protein kinase, putative 0.0064 0.0199 0.0144
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0936 0.0892
Trypanosoma brucei Casein kinase II 0.0098 0.0502 0.0448
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0056 0.0126 0.007
Loa Loa (eye worm) hypothetical protein 0.0068 0.0231 0.0227
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.013 0.0788 0.0736
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0065 0.0209 0.0201
Loa Loa (eye worm) hypothetical protein 0.0045 0.0026 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.1166 1 1
Echinococcus granulosus serine:threonine protein kinase 3 0.0274 0.207 0.2067
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0147 0.0936 0.0932
Schistosoma mansoni tyrosine kinase 0.0069 0.0245 0.0241
Loa Loa (eye worm) TK protein kinase 0.0278 0.21 0.2097
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0081 0.0348 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.1509 0.1506
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0085 0.0386 0.0382
Echinococcus multilocularis mitogen activated protein kinase 11 0.0165 0.1093 0.1089
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0162 0.107 0.1067
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0168 0.1123 0.1116
Schistosoma mansoni tyrosine kinase 0.0219 0.1579 0.1576
Brugia malayi SH2 domain containing protein 0.0069 0.0245 0.0241
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.008 0.0339 0.0331
Schistosoma mansoni tyrosine kinase 0.0401 0.3199 0.3197
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0119 0.0689 0.0637
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0162 0.107 0.1067
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0068 0.0231 0.0223
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.008 0.0339 0.0284
Trichomonas vaginalis CAMK family protein kinase 0.1166 1 1
Brugia malayi Cam kinase protein 1 0.0048 0.0057 0.0053
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0183 0.1254 0.1251
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0085 0.0386 0.0382
Echinococcus multilocularis neuroglian 0.0104 0.0553 0.055
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0643 0.0639
Echinococcus multilocularis insulin receptor 0.0489 0.3976 0.3974
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0502 0.0457
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0246 0.1818 0.1815
Onchocerca volvulus 0.0044 0.0022 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.1166 1 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0523 0.0519
Trichomonas vaginalis CAMK family protein kinase 0.0091 0.0442 0.0397
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0055 0.0117 0.0113
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0211 0.1509 0.1506
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0082 0.0361 0.0358
Echinococcus granulosus tyrosine protein kinase Src42A 0.0162 0.107 0.1067
Echinococcus granulosus myotubularin protein 13 0.0045 0.0027 0.0023
Echinococcus multilocularis Glutaredoxin protein 5 0.0139 0.0867 0.0863
Giardia lamblia Kinase, PLK 0.1166 1 1
Echinococcus multilocularis serine:threonine protein kinase N2 0.0147 0.0936 0.0932
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0936 0.0932
Entamoeba histolytica protein kinase, putative 0.0048 0.0057 0.0001
Echinococcus multilocularis protein kinase c epsilon type 0.0187 0.1291 0.1287
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0339 0.0292
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0689 0.0686
Plasmodium falciparum calcium-dependent protein kinase 5 0.0048 0.0057 0.0005
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0047 0.0048 0.0044
Schistosoma mansoni protein kinase C mu 0.0153 0.099 0.0986
Trichomonas vaginalis CMGC family protein kinase 0.008 0.0339 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0956 0.0913
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0135 0.0832 0.0828
Echinococcus granulosus cyclin dependent kinase 1 0.0119 0.0689 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0316 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.1021 0.1017
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0231 0.0227
Loa Loa (eye worm) TK/INSR protein kinase 0.0489 0.3976 0.3974
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0162 0.1068 0.1061
Trichomonas vaginalis CAMK family protein kinase 0.1166 1 1
Schistosoma mansoni protein kinase 0.0048 0.0057 0.0053
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0502 0.0457
Echinococcus granulosus tyrosine protein kinase HCK 0.0102 0.0536 0.0533
Giardia lamblia Kinase, NEK 0.0139 0.0863 0.0811
Brugia malayi serine/threonine protein kinase 6 0.0149 0.0956 0.0953
Onchocerca volvulus 0.0072 0.027 0.0262
Echinococcus multilocularis casein kinase ii subunit alpha 0.0098 0.0502 0.0499
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0048 0.0057 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.1687 0.1684
Giardia lamblia Kinase, STE STE20 0.0082 0.0361 0.0307
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0047 0.0048 0.004
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0065 0.0209 0.0206
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0082 0.0361 0.0358
Entamoeba histolytica protein kinase, putative 0.0077 0.0316 0.0261
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0068 0.0231 0.0176
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0643 0.0639
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0689 0.0686
Brugia malayi RhoGAP domain containing protein 0.0072 0.0267 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0209 0.0206
Echinococcus multilocularis casein kinase I delta 0.0065 0.0209 0.0206
Entamoeba histolytica protein kinase, putative 0.0058 0.0144 0.0088
Echinococcus multilocularis dual specificity 0.0123 0.0724 0.072
Trichomonas vaginalis conserved hypothetical protein 0.006 0.016 0.0113
Entamoeba histolytica protein kinase, putative 0.0082 0.0361 0.0307
Brugia malayi Protein kinase domain containing protein 0.0069 0.0245 0.0241
Trypanosoma cruzi p21-activated kinase 3, putative 0.0047 0.0048 0.004
Onchocerca volvulus 0.0052 0.009 0.0082
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0048 0.0057 0.0053
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0065 0.0209 0.0206
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0091 0.0442 0.0439
Echinococcus granulosus tyrosine protein kinase Fyn 0.0162 0.107 0.1067
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0936 0.0892
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0048 0.0057 0.0002
Plasmodium falciparum calcium-dependent protein kinase 1 0.0048 0.0057 0.0005
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0068 0.0231 0.0227
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0048 0.0057 0.0534
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0057 0.0053
Echinococcus granulosus aurora kinase A 0.0149 0.0956 0.0953
Brugia malayi Protein kinase domain 0.0082 0.0361 0.0358
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0245 0.0241
Schistosoma mansoni protein kinase 0.0098 0.0502 0.0499
Trichomonas vaginalis STE family protein kinase 0.0082 0.0361 0.0315
Loa Loa (eye worm) TK protein kinase 0.0135 0.0832 0.0828
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0231 0.0227
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0492 0.4 0.3998
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0292 0.0288
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0048 0.0057 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0689 0.0686
Giardia lamblia Kinase, NEK 0.0139 0.0863 0.0811
Trichomonas vaginalis STE family protein kinase 0.0082 0.0361 0.0315
Giardia lamblia Kinase, NEK 0.0139 0.0863 0.0811
Loa Loa (eye worm) hypothetical protein 0.0083 0.0368 0.0365
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0162 0.107 0.1067

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 16.9441 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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