Detailed information for compound 1463875

Basic information

Technical information
  • TDR Targets ID: 1463875
  • Name: 3-(3-chlorophenyl)-1-(1-cyclohexylpyrrolidin- 3-yl)urea
  • MW: 321.845 | Formula: C17H24ClN3O
  • H donors: 2 H acceptors: 1 LogP: 3.6 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cccc(c1)Cl)NC1CCN(C1)C1CCCCC1
  • InChi: 1S/C17H24ClN3O/c18-13-5-4-6-14(11-13)19-17(22)20-15-9-10-21(12-15)16-7-2-1-3-8-16/h4-6,11,15-16H,1-3,7-10,12H2,(H2,19,20,22)
  • InChiKey: QGDPUOFWKLLOFY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(3-chlorophenyl)-1-(1-cyclohexyl-3-pyrrolidinyl)urea
  • STK076100
  • Oprea1_769877
  • TimTec1_004347
  • N-(3-Chlorophenyl)-N'-(1-cyclohexyl-3-pyrrolidinyl)urea
  • Urea, 1-(3-chlorophenyl)-3-(1-cuclohexyl-3-pyrrolidinyl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi pyruvate kinase 2, putative 0.002 0.0201 0.0493
Loa Loa (eye worm) MH2 domain-containing protein 0.0095 0.1693 0.3497
Trichomonas vaginalis histone deacetylase, putative 0.0083 0.1448 0.5238
Schistosoma mansoni histone deacetylase hda2 0.0062 0.1034 0.1034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0506 0.0506
Schistosoma mansoni amine GPCR 0.0036 0.0506 0.0506
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0553 0.1142
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0022 0.0235 0.0646
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0036 0.0506 0.0506
Schistosoma mansoni alpha glucosidase 0.0022 0.0235 0.0235
Schistosoma mansoni rab6-interacting 0.0012 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Schistosoma mansoni aldehyde dehydrogenase 0.0114 0.2068 0.2068
Onchocerca volvulus 0.0036 0.0506 0.1046
Echinococcus multilocularis pyruvate kinase 0.0016 0.0115 0.0115
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0012 0.0041 0.0085
Schistosoma mansoni hypothetical protein 0.0511 1 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0232 0.048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0232 0.048
Plasmodium vivax elongation factor 1-gamma, putative 0.0011 0.0016 0.0084
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0018 0.0147 0.1003
Loa Loa (eye worm) hypothetical protein 0.0182 0.3427 0.7078
Onchocerca volvulus 0.0036 0.0506 0.1046
Loa Loa (eye worm) hypothetical protein 0.0057 0.0929 0.1919
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0652 0.2226
Schistosoma mansoni histone deacetylase 4 5 0.006 0.0991 0.0991
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.0196 0.3707 1
Brugia malayi jmjC domain containing protein 0.0036 0.0512 0.1058
Echinococcus multilocularis chromobox protein 2 0.0018 0.0147 0.0147
Onchocerca volvulus 0.0036 0.0506 0.1046
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0026 0.0319 0.0319
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0036 0.0506 0.1046
Onchocerca volvulus Neuropeptide F receptor homolog 0.0036 0.0506 0.1046
Onchocerca volvulus 0.0036 0.0506 0.1046
Onchocerca volvulus 0.0022 0.0232 0.048
Echinococcus granulosus pyruvate kinase 0.001 0.0002 0.0002
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus lipoxygenase domain containing protein 0.0012 0.0034 0.0034
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.01 0.1786 0.3689
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0232 0.048
Giardia lamblia Pyruvate kinase 0.002 0.0201 0.1374
Brugia malayi neuropeptide F receptor 0.0036 0.0506 0.1046
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0036 0.0512 0.1058
Brugia malayi Histone deacetylase 1 0.0083 0.1448 0.2992
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0235 0.0584
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0036 0.0506 0.1046
Brugia malayi histone deacetylase 11 0.0096 0.1707 0.3526
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0025 0.0051
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0232 0.0232
Echinococcus granulosus glutathione S transferase 0.0038 0.055 0.055
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis glutathione S-transferase 0.0052 0.0822 0.0822
Trypanosoma brucei histone deacetylase 3 0.006 0.0991 0.6808
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0114 0.2068 0.2068
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0147 0.0851
Brugia malayi hypothetical protein 0.0012 0.0041 0.0085
Brugia malayi steroid hormone receptor 0.0022 0.0232 0.048
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0157 0.075
Schistosoma mansoni opsin-like receptor 0.0036 0.0506 0.0506
Trypanosoma cruzi histone deacetylase, putative 0.0036 0.0504 0.1304
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0232 0.048
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0059 0.0965 0.0965
Entamoeba histolytica hypothetical protein 0.0028 0.0357 0.2039
Echinococcus multilocularis glutathione S transferase 0.0043 0.0661 0.0661
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.1799 0.1799
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0232 0.048
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0232 0.0232
Echinococcus multilocularis glutathione S transferase 0.0043 0.0661 0.0661
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0232 0.048
Schistosoma mansoni hypothetical protein 0.0026 0.0319 0.0319
Echinococcus multilocularis pyruvate kinase 0.002 0.0201 0.0201
Echinococcus granulosus 7TM GPCR rhodopsin 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0059 0.0965 0.0965
Echinococcus multilocularis G protein coupled receptor 139 0.0036 0.0506 0.0506
Echinococcus granulosus inositol monophosphatase 1 0.0047 0.0735 0.0735
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0017 0.0124 0.0124
Echinococcus multilocularis allatostatin A receptor 0.0036 0.0506 0.0506
Toxoplasma gondii hypothetical protein 0.0012 0.0041 0.0189
Brugia malayi Calcitonin receptor-like protein seb-1 0.0083 0.1455 0.3006
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Brugia malayi Pre-SET motif family protein 0.0128 0.2355 0.4864
Brugia malayi hypothetical protein 0.0098 0.1743 0.36
Brugia malayi hypothetical protein 0.0018 0.0147 0.0304
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0026 0.0319 0.0319
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0506 0.0506
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0357 0.0563
Leishmania major histone deacetylase, putative 0.006 0.0991 0.2641
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0232 0.0232
Schistosoma mansoni rab6-interacting 0.0012 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0026 0.0319 0.0319
Echinococcus granulosus neuropeptide FF receptor 2 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0018 0.0147 0.0304
Schistosoma mansoni biogenic amine receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis Polycystic kidney disease protein 0.0012 0.0034 0.0034
Echinococcus granulosus g-protein coupled receptor 0.0036 0.0506 0.0506
Echinococcus granulosus Polycystic kidney disease protein 0.0012 0.0034 0.0034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0506 0.0506
Mycobacterium ulcerans aldehyde dehydrogenase 0.0114 0.2068 0.5125
Echinococcus granulosus Pleckstrin G protein interacting region 0.0012 0.0041 0.0041
Mycobacterium ulcerans aldehyde dehydrogenase 0.0114 0.2068 0.5125
Brugia malayi Serotonin receptor 0.0036 0.0506 0.1046
Toxoplasma gondii histone deacetylase HDAC1 0.006 0.0991 0.4787
Onchocerca volvulus Histone deacetylase 10 homolog 0.0036 0.0504 0.1042
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0037 0.0534 0.1103
Trypanosoma brucei pyruvate kinase 1 0.002 0.0201 0.1287
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0147 0.0314
Schistosoma mansoni biogenic amine receptor 0.0036 0.0506 0.0506
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0232 0.048
Schistosoma mansoni neuropeptide receptor 0.0036 0.0506 0.0506
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0528 0.0528
Onchocerca volvulus 0.0036 0.0506 0.1046
Leishmania major fatty acid transporter protein-like protein 0.0196 0.3707 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.0506 0.0506
Brugia malayi Protein cec-1. 0.0018 0.0147 0.0304
Schistosoma mansoni adenoreceptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Loa Loa (eye worm) histone deacetylase 1 0.0083 0.1448 0.2992
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0036 0.0512 0.0512
Trypanosoma brucei histone deacetylase 2 0.0036 0.0504 0.3407
Brugia malayi hypothetical protein 0.0012 0.0034 0.007
Brugia malayi AKH receptor 0.0036 0.0506 0.1046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0232 0.0232
Echinococcus multilocularis serotonin receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0506 0.1046
Brugia malayi Tachykinin-like peptides receptor 99D 0.0036 0.0506 0.1046
Leishmania major histone deacetylase, putative 0.0083 0.1448 0.388
Echinococcus multilocularis lysosomal alpha glucosidase 0.01 0.1786 0.1786
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0232 0.048
Trichomonas vaginalis chromobox protein, putative 0.0065 0.1099 0.3917
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus fmrfamide receptor 0.0036 0.0506 0.0506
Onchocerca volvulus 0.0048 0.0745 0.1538
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0232 0.048
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) pyruvate kinase 0.002 0.0201 0.0415
Toxoplasma gondii transporter, cation channel family protein 0.0012 0.0038 0.0174
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0512 0.0512
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0059 0.0965 0.0965
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0025 0.0025
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0059 0.0965 0.0965
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.1799 0.3716
Schistosoma mansoni histone deacetylase 0.0083 0.1448 0.1448
Echinococcus multilocularis neuropeptide receptor A26 0.0036 0.0506 0.0506
Onchocerca volvulus Pyruvate kinase homolog 0.002 0.0201 0.0415
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0196 0.3707 1
Echinococcus granulosus chromobox protein 1 0.0108 0.1959 0.1959
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0018 0.0147 0.0304
Loa Loa (eye worm) pyruvate kinase-PB 0.0014 0.0077 0.0159
Trichomonas vaginalis histone deacetylase, putative 0.0083 0.1448 0.5238
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus sex peptide receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0506 0.0506
Onchocerca volvulus Huntingtin homolog 0.0098 0.1743 0.36
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus neuropeptide receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis sex peptide receptor 0.0036 0.0506 0.0506
Onchocerca volvulus 0.0146 0.2707 0.5591
Trichomonas vaginalis inositol monophosphatase, putative 0.0047 0.0735 0.2539
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0232 0.0232
Brugia malayi Pyruvate kinase, muscle isozyme 0.002 0.0201 0.0415
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0036 0.0506 0.1046
Schistosoma mansoni survival motor neuron protein 0.0037 0.0534 0.0534
Entamoeba histolytica hypothetical protein 0.0017 0.0124 0.0345
Brugia malayi Pyruvate kinase, M2 isozyme 0.002 0.0201 0.0415
Schistosoma mansoni alpha-glucosidase 0.0086 0.1508 0.1508
Plasmodium falciparum glutathione S-transferase 0.0052 0.0822 0.5669
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0036 0.0512 0.0512
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0128 0.2355 0.4864
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0232 0.048
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.002 0.0188 0.0188
Trypanosoma cruzi histone deacetylase 1, putative 0.0083 0.1448 0.3826
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0022 0.0235 0.115
Loa Loa (eye worm) helicase 0.0018 0.0147 0.0304
Echinococcus granulosus orexin receptor type 2 0.0036 0.0506 0.0506
Onchocerca volvulus 0.0036 0.0506 0.1046
Echinococcus granulosus histone deacetylase 3 0.0083 0.1448 0.1448
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0012 0.0041 0.0041
Echinococcus multilocularis histone deacetylase 8 0.0036 0.0504 0.0504
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0012 0.0041 0.0085
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0506 0.0506
Echinococcus granulosus alpha 1A adrenergic receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0036 0.0506 0.0506
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0147 0.0314
Brugia malayi histone deacetylase 1 (HD1) 0.0083 0.1448 0.2992
Echinococcus multilocularis neuropeptide s receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0083 0.1455 0.3006
Brugia malayi follicle stimulating hormone receptor 0.0036 0.0506 0.1046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0309 0.0929
Echinococcus granulosus chromobox protein 2 0.0018 0.0147 0.0147
Echinococcus granulosus G protein coupled receptor 139 0.0036 0.0506 0.0506
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0019 0.0173 0.083
Schistosoma mansoni neuropeptide f receptor 76f 0.0036 0.0506 0.0506
Echinococcus granulosus regulator of G protein signaling 7 0.0012 0.0041 0.0041
Echinococcus multilocularis sodium channel protein 0.0025 0.029 0.029
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Schistosoma mansoni lipoxygenase 0.0012 0.0034 0.0034
Trichomonas vaginalis pyruvate kinase, putative 0.002 0.0201 0.0517
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0553 0.0553
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0357 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis g-protein coupled receptor 0.0036 0.0506 0.0506
Schistosoma mansoni biogenic amine receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Echinococcus granulosus g protein coupled receptor 0.0036 0.0506 0.0506
Plasmodium vivax multidomain scavenger receptor, putative 0.0012 0.0034 0.0186
Schistosoma mansoni pyruvate kinase 0.002 0.0201 0.0201
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0133 0.2448 0.5056
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0232 0.0232
Echinococcus multilocularis 0.0018 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0079
Brugia malayi Pre-SET motif family protein 0.0019 0.0173 0.0358
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0026 0.0319 0.0319
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0022 0.0225 0.0225
Echinococcus multilocularis voltage dependent calcium channel 0.0059 0.0965 0.0965
Echinococcus multilocularis segment polarity protein dishevelled 0.0012 0.0041 0.0041
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0232 0.0232
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0232 0.048
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0017 0.0124 0.0124
Schistosoma mansoni histone deacetylase 1 2 3 0.0036 0.0504 0.0504
Onchocerca volvulus 0.0036 0.0506 0.1046
Echinococcus granulosus long chain fatty acid transport protein 4 0.0198 0.3759 0.3759
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0025 0.0051
Plasmodium falciparum histone deacetylase 2 0.006 0.0991 0.684
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Schistosoma mansoni dep domain containing protein 0.0012 0.0041 0.0041
Schistosoma mansoni neuropeptide receptor 0.0036 0.0506 0.0506
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0309 0.0929
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0059 0.0965 0.0965
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0309 0.0929
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.002 0.0201 0.0415
Echinococcus granulosus pyruvate kinase 0.001 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Trichomonas vaginalis histone deacetylase, putative 0.0083 0.1448 0.5238
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0083 0.1455 0.3006
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0036 0.0506 0.0506
Echinococcus granulosus glutathione s transferase mu 0.0052 0.0822 0.0822
Onchocerca volvulus 0.0014 0.0064 0.0132
Brugia malayi Heterochromatin protein 1 0.0108 0.1959 0.4047
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0036 0.0506 0.1046
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0232 0.048
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0018 0.0147 0.0304
Echinococcus granulosus regulator of G protein signaling 7 0.0012 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Toxoplasma gondii aldehyde dehydrogenase 0.0114 0.2068 1
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0232 0.048
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0022 0.0235 0.1127
Schistosoma mansoni lipoxygenase 0.0034 0.0468 0.0468
Schistosoma mansoni neuropeptide receptor 0.0036 0.0506 0.0506
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0018 0.0147 0.0702
Loa Loa (eye worm) hypothetical protein 0.0014 0.0064 0.0132
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0232 0.0232
Loa Loa (eye worm) TYRA-2 protein 0.0036 0.0506 0.1046
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Schistosoma mansoni amine GPCR 0.0036 0.0506 0.0506
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0173 0.0173
Echinococcus granulosus glutathione S transferase Mu 1 0.0022 0.0225 0.0225
Trypanosoma brucei glucosidase, putative 0.0022 0.0235 0.1526
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0036 0.0506 0.0506
Toxoplasma gondii histone deacetylase HDAC3 0.0083 0.1448 0.6998
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus segment polarity protein dishevelled 0.0012 0.0041 0.0041
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0357 0.0536
Schistosoma mansoni dishevelled 0.0012 0.0041 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0014 0.0077 0.0159
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0047 0.0735 0.1921
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0232 0.048
Plasmodium falciparum elongation factor 1-gamma, putative 0.0011 0.0016 0.0099
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0036 0.0506 0.1046
Onchocerca volvulus 0.0036 0.0506 0.1046
Leishmania major pyruvate kinase 0.002 0.0201 0.0499
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0018 0.0147 0.1003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0051
Plasmodium vivax histone deacetylase 2, putative 0.006 0.0991 0.5802
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0506 0.0506
Echinococcus granulosus hypothetical protein 0.0036 0.0506 0.0506
Brugia malayi Serotonin receptor 0.0036 0.0506 0.1046
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0147 0.051
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0018 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0048 0.0745 0.1538
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0357 0.0536
Trichomonas vaginalis hypothetical protein 0.0018 0.0147 0.0314
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0157 0.0376
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0232 0.0232
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.1799 0.1799
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0036 0.0512 0.0512
Brugia malayi nuclear hormone receptor 0.0022 0.0232 0.048
Plasmodium vivax histone deacetylase, putative 0.006 0.0991 0.5802
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0085
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0083 0.1455 0.3006
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0025 0.0025
Echinococcus granulosus lipoxygenase domain containing protein 0.0012 0.0034 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0232 0.048
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0506 0.0506
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0083 0.1448 0.5238
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0253 0.4841 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0147 0.051
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0235 0.0646
Loa Loa (eye worm) CXXC zinc finger family protein 0.0036 0.0509 0.1052
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0232 0.0232
Plasmodium vivax SET domain protein, putative 0.0019 0.0173 0.1005
Onchocerca volvulus 0.0036 0.0506 0.1046
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0506 0.0506
Trypanosoma cruzi pyruvate kinase 2, putative 0.002 0.0201 0.0493
Trichomonas vaginalis chromobox protein, putative 0.0108 0.1959 0.7171
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0077 0.1326 0.1326
Schistosoma mansoni hypothetical protein 0.0026 0.0319 0.0319
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0374 0.7274 0.7274
Loa Loa (eye worm) hypothetical protein 0.0018 0.0147 0.0304
Onchocerca volvulus 0.0036 0.0506 0.1046
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0025 0.0025
Echinococcus granulosus g protein coupled receptor 0.0036 0.0506 0.0506
Entamoeba histolytica hypothetical protein 0.0018 0.0147 0.051
Echinococcus granulosus histone deacetylase 6 0.006 0.0991 0.0991
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0025 0.0025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0232 0.0232
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0232 0.048
Trichomonas vaginalis sucrase-isomaltase, putative 0.0022 0.0235 0.0646
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0083 0.1448 0.5238
Schistosoma mansoni hypothetical protein 0.0017 0.0124 0.0124
Echinococcus granulosus survival motor neuron protein 1 0.0182 0.3427 0.3427
Schistosoma mansoni hypothetical protein 0.0036 0.0506 0.0506
Schistosoma mansoni chromobox protein 0.0108 0.1959 0.1959
Brugia malayi Melatonin receptor type 1A 0.0036 0.0506 0.1046
Brugia malayi G protein-coupled receptor 0.0036 0.0506 0.1046
Echinococcus granulosus histone deacetylase 8 0.0036 0.0504 0.0504
Loa Loa (eye worm) hypothetical protein 0.0059 0.0965 0.1994
Schistosoma mansoni hypothetical protein 0.0018 0.0157 0.0157
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0205 0.3887 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0036 0.0506 0.1046
Brugia malayi ecdysteroid receptor 0.0022 0.0232 0.048
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0047 0.0735 0.2539
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis lysosomal alpha glucosidase 0.01 0.1786 0.1786
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0309 0.0929
Loa Loa (eye worm) hypothetical protein 0.0061 0.1007 0.208
Schistosoma mansoni voltage-gated cation channel 0.0059 0.0965 0.0965
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0047 0.0735 1
Onchocerca volvulus 0.0058 0.0946 0.1953
Echinococcus granulosus eukaryotic translation elongation factor 1 0.0011 0.0016 0.0016
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0506 0.0506
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.0506 0.0506
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0036 0.0506 0.0506
Onchocerca volvulus 0.0012 0.0034 0.007
Schistosoma mansoni myosin xvIII 0.0036 0.0506 0.0506
Brugia malayi G protein-coupled receptor F59B2.13 0.0036 0.0506 0.1046
Echinococcus multilocularis Chromobox protein 3 0.0018 0.0147 0.0147
Schistosoma mansoni FFA transport protein 0.0198 0.3759 0.3759
Echinococcus multilocularis glutathione S transferase 0.0052 0.0822 0.0822
Loa Loa (eye worm) heterochromatin protein 1 0.0108 0.1959 0.4047
Echinococcus granulosus cpg binding protein 0.0038 0.055 0.055
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0022 0.0225 0.0225
Brugia malayi Cytochrome P450 family protein 0.0027 0.0337 0.0697
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0506 0.0506
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0506 0.0506
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0357 0.0922
Schistosoma mansoni hypothetical protein 0.0037 0.0534 0.0534
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0018 0.0147 0.0147
Loa Loa (eye worm) cytochrome P450 0.0018 0.0157 0.0324
Brugia malayi hypothetical protein 0.0012 0.0034 0.007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi Associated with TFs and helicases family protein 0.0018 0.0147 0.0304
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis histone deacetylase 6 0.006 0.0991 0.0991
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0028 0.0057
Echinococcus granulosus peptide allatostatin:somatostatin 0.0036 0.0506 0.0506
Echinococcus granulosus tachykinin peptides receptor 99D 0.0036 0.0506 0.0506
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Echinococcus multilocularis dnaJ subfamily B 0.0511 1 1
Entamoeba histolytica hypothetical protein 0.0017 0.0124 0.0345
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.0506 0.0506
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0047 0.0735 0.4799
Toxoplasma gondii elongation factor 1-gamma, putative 0.0011 0.0016 0.0069
Echinococcus granulosus histone deacetylase 0.006 0.0991 0.0991
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0173 0.0173
Onchocerca volvulus 0.0036 0.0506 0.1046
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0036 0.0506 0.0506
Brugia malayi Cytochrome P450 family protein 0.0018 0.0157 0.0324
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0018 0.0147 0.0147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0232 0.048
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.002 0.0188 0.0188
Brugia malayi CXXC zinc finger family protein 0.0036 0.0509 0.1052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0019 0.0173 0.0173
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0232 0.0232
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0232 0.0232
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0026 0.0319 0.0658
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0337 0.0484
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0022 0.0235 0.115
Schistosoma mansoni alpha-1 adrenergic receptor 0.0036 0.0506 0.0506
Echinococcus granulosus pyruvate kinase 0.002 0.0201 0.0201
Schistosoma mansoni amine GPCR 0.0036 0.0506 0.0506
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0157 0.0157
Leishmania major cytochrome p450-like protein 0.0018 0.0157 0.0381
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0061 0.1007 0.208
Onchocerca volvulus 0.0036 0.0509 0.1052
Echinococcus multilocularis GPCR, family 2 0.0026 0.0319 0.0319
Echinococcus granulosus glutathione S transferase 0.0052 0.0822 0.0822
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0051
Echinococcus granulosus serotonin receptor 0.0036 0.0506 0.0506
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0036 0.0506 0.0506
Echinococcus granulosus neuropeptide receptor A26 0.0036 0.0506 0.0506
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0028 0.0028
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0157 0.0376
Brugia malayi Latrophilin receptor protein 2 0.0026 0.0319 0.0658
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0114 0.2068 0.5385
Loa Loa (eye worm) hypothetical protein 0.0022 0.0232 0.048
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0036 0.0506 0.1046
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0506 0.0506
Brugia malayi neuropeptide F receptor 0.0036 0.0506 0.1046
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0506 0.0506
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0309 0.0929
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.0506 0.0506
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0018 0.0147 0.0702
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0022 0.0235 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0147 0.0314
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0018 0.0147 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0147 0.0314
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0036 0.0506 0.0506
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0042 0.0636 0.1351
Schistosoma mansoni z-protein (S1r protein) 0.0012 0.0041 0.0041
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0036 0.0506 0.1308
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0232 0.0232
Echinococcus granulosus segment polarity protein dishevelled 0.0012 0.0041 0.0041
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0018 0.0147 0.0702
Schistosoma mansoni amine GPCR 0.0036 0.0506 0.0506
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0222 0.0599
Schistosoma mansoni hypothetical protein 0.0036 0.0506 0.0506
Echinococcus granulosus neuropeptide s receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0234 0.0644
Loa Loa (eye worm) pyruvate kinase 0.002 0.0201 0.0415
Brugia malayi Dopamine receptor 0.0036 0.0506 0.1046
Loa Loa (eye worm) hypothetical protein 0.0019 0.0173 0.0358
Brugia malayi G-protein coupled receptor 0.0036 0.0506 0.1046
Echinococcus multilocularis glutathione S transferase 0.0038 0.055 0.055
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0652 0.2226
Echinococcus multilocularis Chromo domain 0.0018 0.0147 0.0147
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0235 0.0646
Echinococcus multilocularis inositol monophosphatase 1 0.0047 0.0735 0.0735
Echinococcus granulosus voltage dependent calcium channel 0.0012 0.0038 0.0038
Brugia malayi Valyl-tRNA synthetase 0.0018 0.0147 0.0304
Echinococcus multilocularis lipoxygenase domain containing protein 0.0012 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0506 0.0506
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0506 0.0506
Schistosoma mansoni cpg binding protein 0.0038 0.055 0.055
Onchocerca volvulus 0.0036 0.0506 0.1046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi M-phase phosphoprotein, mpp8 0.0018 0.0147 0.0304
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus chromobox protein 1 0.0108 0.1959 0.1959
Echinococcus multilocularis pyruvate kinase 0.001 0.0002 0.0002
Echinococcus multilocularis histone deacetylase 6 0.006 0.0991 0.0991
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0147 0.0314
Brugia malayi nuclear receptor NHR-88 0.0022 0.0232 0.048
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0036 0.0506 0.0506
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi Glycosyl hydrolases family 31 protein 0.0022 0.0235 0.0485
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0059 0.0965 0.0965
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0036 0.0512 0.0512
Echinococcus granulosus neutral alpha glucosidase AB 0.0022 0.0235 0.0235
Echinococcus multilocularis regulator of G protein signaling 7 0.0012 0.0041 0.0041
Echinococcus multilocularis histone deacetylase 6 0.0062 0.1034 0.1034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0322 0.0666
Loa Loa (eye worm) hypothetical protein 0.0026 0.0319 0.0658
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0034 0.0468 0.0468
Brugia malayi Glutathione S-transferase 4 0.0014 0.0064 0.0132
Echinococcus granulosus lysosomal alpha glucosidase 0.01 0.1786 0.1786
Loa Loa (eye worm) hypothetical protein 0.0018 0.0147 0.0304
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0309 0.0929
Brugia malayi cytochrome P450 0.0018 0.0157 0.0324
Onchocerca volvulus 0.0018 0.0147 0.0304
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0173 0.0173
Brugia malayi G-protein coupled receptor 0.0036 0.0506 0.1046
Echinococcus multilocularis pyruvate kinase 0.001 0.0002 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0147 0.0314
Schistosoma mansoni histone deacetylase 0.0083 0.1448 0.1448
Brugia malayi hypothetical protein 0.0012 0.0025 0.0051
Leishmania major pyruvate kinase 0.002 0.0201 0.0499
Brugia malayi RE15519p 0.0036 0.0506 0.1046
Schistosoma mansoni pyruvate kinase 0.002 0.0201 0.0201
Echinococcus multilocularis histone deacetylase 3 0.0083 0.1448 0.1448
Schistosoma mansoni elongation factor 1-gamma 0.0011 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0022 0.0232 0.048
Echinococcus granulosus voltage dependent calcium channel 0.0059 0.0965 0.0965
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0506 0.0506
Mycobacterium ulcerans aldehyde dehydrogenase 0.0114 0.2068 0.5125
Plasmodium falciparum histone deacetylase, putative 0.006 0.0991 0.684
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Trypanosoma brucei histone deacetylase, putative 0.006 0.0991 0.6808
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0232 0.048
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0232 0.0232
Echinococcus granulosus 7tm_1 domain containing protein 0.0036 0.0506 0.0506
Echinococcus granulosus prostaglandin H2 D isomerase 0.0022 0.0225 0.0225
Mycobacterium ulcerans pyruvate kinase 0.002 0.0201 0.0117
Brugia malayi ORL1-like opioid receptor 0.0036 0.0506 0.1046
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0025 0.0051
Onchocerca volvulus 0.0036 0.0506 0.1046
Brugia malayi hypothetical protein 0.0017 0.0124 0.0257
Loa Loa (eye worm) hypothetical protein 0.0022 0.0232 0.048
Echinococcus multilocularis histone deacetylase 0.006 0.0991 0.0991
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0085
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0051
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0235 0.0646
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0506 0.1046
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0028 0.0357 0.5
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0036 0.0506 0.1046
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0025 0.0025
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0025 0.029 0.029
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0512 0.0512
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0232 0.0232
Echinococcus multilocularis glutathione S transferase 0.0038 0.055 0.055
Echinococcus multilocularis glutathione s transferase mu 0.0052 0.0822 0.0822
Echinococcus multilocularis orexin receptor type 2 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0504 0.1042
Echinococcus multilocularis long chain fatty acid transport protein 4 0.0198 0.3759 0.3759
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) voltage-dependent calcium channel 0.0012 0.0038 0.0079
Echinococcus multilocularis glutathione S transferase 0.0052 0.0822 0.0822
Loa Loa (eye worm) hypothetical protein 0.0012 0.0025 0.0051
Echinococcus granulosus histone deacetylase 1 0.0083 0.1448 0.1448
Brugia malayi MH2 domain containing protein 0.0095 0.1693 0.3497
Loa Loa (eye worm) CHromoDomain protein family member 0.002 0.0188 0.0388
Brugia malayi nuclear receptor RXR 0.0012 0.0025 0.0051
Loa Loa (eye worm) hypothetical protein 0.006 0.0995 0.2056
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0337 0.0697
Brugia malayi putative neuropeptide receptor 0.0036 0.0506 0.1046
Loa Loa (eye worm) hypothetical protein 0.0083 0.1448 0.2992
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Trichomonas vaginalis maltase-glucoamylase, putative 0.0022 0.0235 0.0646
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Trypanosoma brucei pyruvate kinase 1, putative 0.002 0.0201 0.1287
Trypanosoma cruzi histone deacetylase, putative 0.0036 0.0504 0.1304
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Schistosoma mansoni alpha-glucosidase 0.0086 0.1508 0.1508
Plasmodium vivax pyruvate kinase, putative 0.002 0.0201 0.1165
Echinococcus granulosus dro:myosuppressin receptor 0.0036 0.0506 0.0506
Schistosoma mansoni histone deacetylase hda2 0.0036 0.0504 0.0504
Echinococcus multilocularis RUN 0.0012 0.0034 0.0034
Brugia malayi histone deacetylase 3 (HD3) 0.0083 0.1448 0.2992
Loa Loa (eye worm) histone deacetylase 3 0.0083 0.1448 0.2992
Brugia malayi sulfakinin receptor protein 0.0036 0.0506 0.1046
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0235 0.0584
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Trichomonas vaginalis chromobox protein, putative 0.0065 0.1099 0.3917
Leishmania major histone deacetylase, putative 0.0083 0.1448 0.388
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Loa Loa (eye worm) histone deacetylase 11 0.0096 0.1707 0.3526
Loa Loa (eye worm) latrophilin receptor protein 2 0.0026 0.0319 0.0658
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Brugia malayi AMP-binding enzyme family protein 0.0205 0.3887 0.803
Echinococcus multilocularis G-protein coupled receptor, putative 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0024 0.028 0.0577
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0205 0.3887 0.803
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0506 0.0506
Toxoplasma gondii hypothetical protein 0.0011 0.0008 0.0031
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0232 0.0232
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0512 0.0512
Echinococcus multilocularis lipoxygenase domain containing protein 0.0012 0.0034 0.0034
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0553 0.0553
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0337 0.2242
Entamoeba histolytica histone deacetylase, putative 0.0083 0.1448 1
Schistosoma mansoni cpg binding protein 0.0038 0.055 0.055
Trichomonas vaginalis chromobox protein, putative 0.0018 0.0147 0.0314
Brugia malayi N-terminal motif family protein 0.0253 0.4841 1
Toxoplasma gondii pyruvate kinase PyK1 0.002 0.0201 0.0961
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0018 0.0147 0.0147
Trichomonas vaginalis chromobox protein, putative 0.0018 0.0147 0.0314
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0036 0.0512 0.1058
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.1007 0.3568
Echinococcus granulosus allatostatin A receptor 0.0036 0.0506 0.0506
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0034 0.0468 0.0468
Onchocerca volvulus 0.0018 0.0147 0.0304
Leishmania major histone deacetylase, putative 0.006 0.0991 0.2641
Schistosoma mansoni histone deacetylase 4 5 0.006 0.0991 0.0991
Brugia malayi hypothetical protein 0.0012 0.0025 0.0051
Schistosoma mansoni cpg binding protein 0.0036 0.0509 0.0509
Toxoplasma gondii histone deacetylase HDAC4 0.0096 0.1707 0.8251
Loa Loa (eye worm) doublecortin family protein 0.0012 0.0034 0.007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0232 0.048
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0036 0.0506 0.0506
Schistosoma mansoni chromobox protein 0.0108 0.1959 0.1959
Schistosoma mansoni inositol monophosphatase 0.0047 0.0735 0.0735
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0232 0.048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Echinococcus multilocularis somatostatin receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0232 0.048
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0506 0.0506
Brugia malayi CHD4 protein 0.002 0.0188 0.0388
Trypanosoma cruzi histone deacetylase, putative 0.006 0.0991 0.2605
Leishmania major cytochrome p450-like protein 0.0027 0.0337 0.087
Brugia malayi latrophilin 2 splice variant baaae 0.0057 0.0929 0.1919
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Entamoeba histolytica hypothetical protein 0.0018 0.0147 0.051
Schistosoma mansoni loxhd1 0.0012 0.0034 0.0034
Brugia malayi hypothetical protein 0.0012 0.0041 0.0085
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0042 0.0636 0.1351
Echinococcus multilocularis segment polarity protein dishevelled 0.0012 0.0041 0.0041
Schistosoma mansoni cytochrome P450 0.0018 0.0157 0.0157
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0357 0.2453
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0357 0.2377
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0083 0.1448 0.5238
Entamoeba histolytica hypothetical protein 0.0017 0.0124 0.0345
Brugia malayi hypothetical protein 0.0182 0.3427 0.7078
Schistosoma mansoni dishevelled 0.0012 0.0041 0.0041
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0059 0.0965 0.0965
Echinococcus granulosus Chromo domain 0.0018 0.0147 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0232 0.048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0232 0.048
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0036 0.0506 0.0506
Brugia malayi GnHR receptor homolog 0.0036 0.0506 0.1046
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0026 0.0319 0.0319
Schistosoma mansoni hypothetical protein 0.0057 0.0929 0.0929
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0337 0.0858
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0059 0.0965 0.1994
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0506 0.0506
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0232 0.0232
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0047 0.0735 0.1948
Loa Loa (eye worm) hypothetical protein 0.0253 0.4841 1
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0025 0.0051
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0157 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0147 0.0314
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0036 0.0506 0.0506
Giardia lamblia Histone deacetylase 0.0083 0.1448 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0047 0.0735 0.502
Schistosoma mansoni polycystin 1-related 0.0012 0.0034 0.0034
Onchocerca volvulus Pyruvate kinase homolog 0.002 0.0201 0.0415
Loa Loa (eye worm) hypothetical protein 0.0018 0.0147 0.0304
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0232 0.048
Echinococcus multilocularis eukaryotic translation elongation factor 1 0.0011 0.0016 0.0016
Echinococcus multilocularis chromobox protein 1 0.0108 0.1959 0.1959
Echinococcus multilocularis histone deacetylase 1 0.0083 0.1448 0.1448
Echinococcus granulosus histone deacetylase 6 0.006 0.0991 0.0991
Entamoeba histolytica hypothetical protein 0.0018 0.0147 0.051
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.1164 0.5622
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0047 0.0735 0.3548
Brugia malayi glutathione transferase 0.0133 0.2448 0.5056
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0198 0.3759 1
Onchocerca volvulus 0.0036 0.0506 0.1046
Schistosoma mansoni aldehyde dehydrogenase 0.0114 0.2068 0.2068
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0147 0.0314
Plasmodium vivax heterochromatin protein 1, putative 0.0018 0.0147 0.0851
Loa Loa (eye worm) transcription factor SMAD2 0.0095 0.1693 0.3497
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0036 0.0512 0.0512
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0232 0.0232
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0337 0.0697
Schistosoma mansoni hypothetical protein 0.0012 0.0034 0.0034
Leishmania major alpha glucosidase II subunit, putative 0.0022 0.0235 0.0592
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0012 0.0041 0.0085
Plasmodium vivax histone deacetylase 1, putative 0.0083 0.1448 0.8482
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0506 0.0506
Echinococcus granulosus Chromobox protein 3 0.0018 0.0147 0.0147
Echinococcus granulosus neuropeptide receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0036 0.0506 0.1046
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0232 0.0232
Onchocerca volvulus 0.0036 0.0506 0.1046
Loa Loa (eye worm) hypothetical protein 0.01 0.1799 0.3716
Echinococcus multilocularis cpg binding protein 0.0038 0.055 0.055
Plasmodium falciparum histone deacetylase 1 0.0083 0.1448 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0065 0.1099 0.2271
Brugia malayi hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0022 0.0232 0.048
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0059 0.0965 0.0965
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi chromobox protein homolog 3 0.0061 0.1007 0.208
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0506 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.1007 0.3568
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0235 0.0646
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0309 0.0929
Echinococcus multilocularis chromobox protein 1 0.0108 0.1959 0.1959
Schistosoma mansoni amine GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Echinococcus multilocularis glutathione S transferase 0.0022 0.0225 0.0225
Echinococcus granulosus glutathione S transferase 0.0038 0.055 0.055
Trichomonas vaginalis histone deacetylase, putative 0.0083 0.1448 0.5238
Echinococcus multilocularis survival motor neuron protein 1 0.0182 0.3427 0.3427
Echinococcus granulosus glutathione S transferase 0.0014 0.0064 0.0064
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0022 0.0232 0.048
Brugia malayi jmjC domain containing protein 0.0038 0.0553 0.1142
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.002 0.0201 0.0123
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0234 0.0644
Schistosoma mansoni pyruvate kinase 0.001 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0232 0.048
Trichomonas vaginalis Heterochromatin protein, putative 0.0018 0.0147 0.0314
Echinococcus multilocularis neutral alpha glucosidase AB 0.0022 0.0235 0.0235
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0018 0.0147 0.0147
Brugia malayi Histone deacetylase family protein 0.006 0.0991 0.2047
Trichomonas vaginalis pyruvate kinase, putative 0.002 0.0201 0.0517
Onchocerca volvulus 0.0012 0.0034 0.007
Trypanosoma cruzi histone deacetylase, putative 0.006 0.0991 0.2605
Brugia malayi SET domain containing protein 0.0019 0.0176 0.0364
Echinococcus multilocularis pyruvate kinase 0.002 0.0201 0.0201
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0232 0.0232
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0506 0.0506
Echinococcus granulosus GPCR family 2 0.0026 0.0319 0.0319
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0173 0.0173
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0114 0.2068 0.556
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0059 0.0965 0.0965
Loa Loa (eye worm) hypothetical protein 0.0098 0.1743 0.36
Schistosoma mansoni regulator of G protein signaling 0.0012 0.0041 0.0041
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0036 0.0506 0.1046
Trypanosoma cruzi histone deacetylase 1, putative 0.0083 0.1448 0.3826
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.007
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0357 0.2081
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis regulator of G protein signaling 7 0.0012 0.0041 0.0041
Schistosoma mansoni histamine h1 receptor 0.0036 0.0506 0.0506
Schistosoma mansoni opsin-like receptor 0.0036 0.0506 0.0506
Trypanosoma brucei histone deacetylase 1 0.0083 0.1448 1
Trichomonas vaginalis histone deacetylase, putative 0.0083 0.1448 0.5238
Trichomonas vaginalis histone deacetylase, putative 0.0083 0.1448 0.5238
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0337 0.0697
Brugia malayi Cytochrome P450 family protein 0.0027 0.0337 0.0697
Loa Loa (eye worm) inositol-1 0.0047 0.0735 0.1519
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0506 0.1046
Schistosoma mansoni transcription factor LCR-F1 0.0017 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Plasmodium vivax histone deacetylase, putative 0.0096 0.1707 1
Echinococcus multilocularis serotonin receptor 0.0036 0.0506 0.0506
Onchocerca volvulus 0.01 0.1799 0.3716
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0147 0.051
Toxoplasma gondii histone deacetylase HDAC2 0.0083 0.1448 0.6998
Onchocerca volvulus 0.0037 0.0534 0.1103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0506 0.0506
Echinococcus multilocularis pyruvate kinase 0.001 0.0002 0.0002
Brugia malayi regulator of G-protein signaling egl-10 0.0012 0.0041 0.0085
Trichomonas vaginalis chromobox protein, putative 0.0108 0.1959 0.7171
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0512 0.0512
Schistosoma mansoni chromobox protein 0.0018 0.0147 0.0147
Echinococcus multilocularis neuropeptide FF receptor 2 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.007
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0147 0.0851
Loa Loa (eye worm) hypothetical protein 0.0018 0.0147 0.0304
Echinococcus granulosus histone deacetylase 6 0.0062 0.1034 0.1034
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0012 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0147 0.0304
Schistosoma mansoni neuropeptide receptor 0.0036 0.0506 0.0506
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0232 0.048
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0357 0.1717
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0047 0.0735 0.2539
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0036 0.0506 0.0506
Schistosoma mansoni coup transcription factor 0.0022 0.0232 0.0232
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0036 0.0506 0.1046
Brugia malayi Doublecortin family protein 0.0012 0.0034 0.007
Brugia malayi Histone deacetylase family protein 0.006 0.0991 0.2047
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.0026 0.0319 0.0319
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.1799 0.1799
Schistosoma mansoni chromodomain helicase DNA binding protein 0.002 0.0188 0.0188
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0232 0.048
Echinococcus granulosus pyruvate kinase 0.001 0.0002 0.0002
Trypanosoma brucei histone deacetylase 4 0.006 0.0991 0.6808
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0036 0.0506 0.0506
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0036 0.0506 0.0506
Onchocerca volvulus 0.0036 0.0506 0.1046
Loa Loa (eye worm) DIX domain-containing protein 0.0012 0.0041 0.0085
Trichomonas vaginalis chromobox protein, putative 0.0018 0.0147 0.0314
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0357 0.1717
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0232 0.0232
Loa Loa (eye worm) pyruvate kinase 0.002 0.0201 0.0415
Plasmodium vivax glutathione S-transferase, putative 0.0022 0.0225 0.131
Schistosoma mansoni growth hormone secretagogue receptor 0.0036 0.0506 0.0506
Entamoeba histolytica hypothetical protein 0.0017 0.0124 0.0345
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0232 0.0232
Echinococcus granulosus pyruvate kinase 0.002 0.0201 0.0201
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0232 0.048
Echinococcus multilocularis voltage dependent calcium channel 0.0059 0.0965 0.0965
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0309 0.0929
Onchocerca volvulus 0.0036 0.0506 0.1046
Echinococcus granulosus histone deacetylase 7 0.006 0.0991 0.0991
Trypanosoma cruzi histone deacetylase, putative 0.006 0.0991 0.2605
Loa Loa (eye worm) calcium channel 0.0059 0.0965 0.1994
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0357 0.0563
Loa Loa (eye worm) hypothetical protein 0.0098 0.1743 0.36
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0232 0.0232
Schistosoma mansoni glutathione-S-transferase 0.0052 0.0822 0.0822
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0198 0.3759 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0114 0.2068 0.2068
Onchocerca volvulus Pyruvate kinase homolog 0.002 0.0201 0.0415
Brugia malayi Cytochrome P450 family protein 0.0058 0.0943 0.1948
Onchocerca volvulus 0.0012 0.0041 0.0085
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0506 0.0506
Loa Loa (eye worm) melatonin receptor type 1A 0.0036 0.0506 0.1046
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0157 0.0376
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0147 0.0314
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0337 0.0858
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0173 0.0173
Brugia malayi putative neuropeptide receptor NPR1 0.0036 0.0506 0.1046
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0235 0.0646
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0157 0.0381
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0232 0.048
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0036 0.0506 0.3418
Trichomonas vaginalis set domain proteins, putative 0.0146 0.2707 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0506 0.1046
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0232 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0147 0.0314
Schistosoma mansoni opsin-like receptor 0.0036 0.0506 0.0506
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0232 0.048
Brugia malayi larval opioid receptor 0.0036 0.0506 0.1046
Loa Loa (eye worm) histone deacetylase 0.006 0.0991 0.2047
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0036 0.0512 0.0512
Plasmodium falciparum heterochromatin protein 1 0.0018 0.0147 0.1003
Schistosoma mansoni GST class-mu 0.0052 0.0822 0.0822
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0506 0.0506
Echinococcus granulosus g protein coupled receptor 0.0036 0.0506 0.0506
Echinococcus multilocularis dro:myosuppressin receptor 0.0036 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi Dopamine receptor protein 2 0.0036 0.0506 0.1046
Echinococcus granulosus RUN 0.0012 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Brugia malayi Glycosyl hydrolases family 31 protein 0.01 0.1786 0.3689
Echinococcus multilocularis histone deacetylase 7 0.006 0.0991 0.0991
Brugia malayi Dopamine receptor protein 1 0.0036 0.0506 0.1046
Onchocerca volvulus Huntingtin homolog 0.0098 0.1743 0.36
Onchocerca volvulus 0.0037 0.0528 0.1091
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0147 0.0314
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0022 0.0235 0.0646
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0012 0.0041 0.0085
Plasmodium falciparum pyruvate kinase 0.002 0.0201 0.1374
Loa Loa (eye worm) histone deacetylase 7A 0.006 0.0991 0.2047
Leishmania major cytochrome p450-like protein 0.0018 0.0157 0.0381
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0018 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0012 0.0041 0.0085
Mycobacterium leprae Probable pyruvate kinase PykA 0.002 0.0201 0.0123
Brugia malayi DIX domain containing protein 0.0012 0.0041 0.0085
Schistosoma mansoni chromobox protein 0.0018 0.0147 0.0147
Schistosoma mansoni hypothetical protein 0.0036 0.0506 0.0506
Brugia malayi Inositol-1 0.0047 0.0735 0.1519
Echinococcus granulosus somatostatin receptor 0.0036 0.0506 0.0506
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0232 0.0232
Toxoplasma gondii histone deacetylase HDAC5 0.0036 0.0504 0.243
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0512 0.0512
Schistosoma mansoni inositol monophosphatase 0.0047 0.0735 0.0735
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0943 0.1948
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0047 0.0735 0.155
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0047 0.0735 0.1921
Plasmodium falciparum LCCL domain-containing protein 0.0012 0.0034 0.022
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0506 0.1046
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0036 0.0506 0.0506

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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