Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.026 | 0.2324 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Schistosoma mansoni | thyroid hormone receptor | 0.004 | 0.0058 | 0.0189 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0245 | 0.0573 | 0.1903 |
Onchocerca volvulus | 0.0072 | 0.0137 | 0.2346 | |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0343 | 0.3058 |
Echinococcus granulosus | muscleblind protein | 0.0155 | 0.0347 | 0.114 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0051 | 0.0084 | 0.0265 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0071 | 0.0232 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0072 | 0.0137 | 0.0228 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0072 | 0.0137 | 0.0228 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0004 | 0.0028 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0072 | 0.0137 | 0.0228 |
Mycobacterium leprae | Probable pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) | 0.2412 | 0.6025 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0019 | 0.0004 | 0.0028 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0137 | 0.1217 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0236 | 0.0549 | 0.1823 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0049 | 0.0428 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.001 | 0.008 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.004 | 0.0058 | 0.0178 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0015 | 0.0547 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0049 | 0.0724 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0051 | 0.0086 | 0.0118 |
Leishmania major | hypothetical protein, conserved | 0.0045 | 0.0071 | 0.3529 |
Echinococcus granulosus | heat shock protein 90 | 0.0051 | 0.0086 | 0.0272 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0019 | 0.0004 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0082 | 0.0731 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0093 | 0.0192 | 0.1711 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0049 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0021 | 0.001 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.004 | 0.0058 | 0.0053 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0263 | 0.0617 | 1 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0026 | 0.0023 | 0.0019 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0049 | 0.0724 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.0199 | 0.066 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.003 |
Leishmania major | basic transcription factor 3a, putative | 0.0035 | 0.0045 | 0.2171 |
Schistosoma mansoni | cpg binding protein | 0.0127 | 0.0276 | 0.0917 |
Schistosoma mansoni | endoplasmin | 0.0065 | 0.0119 | 0.0393 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0093 | 0.0192 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0065 | 0.0119 | 0.6111 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.025 | 0.2226 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0137 | 0.2165 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.0192 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0015 | 0.0123 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0093 | 0.0192 | 0.2726 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0137 | 0.0133 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0052 | 0.0088 | 0.0787 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0049 | 0.0647 |
Echinococcus granulosus | endoplasmin | 0.0051 | 0.0086 | 0.0272 |
Mycobacterium leprae | Probable lipase LipE | 0.0072 | 0.0137 | 0.0204 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0051 | 0.0086 | 0.0142 |
Schistosoma mansoni | hypothetical protein | 0.0121 | 0.026 | 0.0863 |
Schistosoma mansoni | coup transcription factor | 0.004 | 0.0058 | 0.0189 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0125 | 0.0272 | 0.089 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0015 | 0.0024 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0005 | 0.0329 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0005 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus multilocularis | protein dispatched 1 | 0.0143 | 0.0316 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Loa Loa (eye worm) | steroid hormone receptor | 0.004 | 0.0058 | 0.0514 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.0001 | 0.0008 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0417 | 0.1006 | 0.1003 |
Plasmodium vivax | heat shock protein, putative | 0.0026 | 0.0023 | 0.1675 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0031 | 0.0034 | 0.003 |
Echinococcus granulosus | geminin | 0.0841 | 0.2071 | 0.6881 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0292 | 0.0691 | 0.0687 |
Echinococcus granulosus | cpg binding protein | 0.0127 | 0.0276 | 0.0907 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.004 | 0.0058 | 0.0506 |
Mycobacterium tuberculosis | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) | 0.2412 | 0.6025 | 1 |
Leishmania major | heat shock protein, putative | 0.0026 | 0.0023 | 0.0986 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0015 | 0.0123 |
Schistosoma mansoni | cpg binding protein | 0.0127 | 0.0276 | 0.0917 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0065 | 0.0119 | 0.1061 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0031 | 0.0034 | 0.1585 |
Schistosoma mansoni | nuclear hormone receptor | 0.004 | 0.0058 | 0.0189 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.0113 | 0.0374 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.004 | 0.0058 | 0.0506 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0045 | 0.2171 |
Loa Loa (eye worm) | endoplasmin | 0.0065 | 0.0119 | 0.1061 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.004 | 0.0058 | 0.0178 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.004 | 0.0058 | 0.0506 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0019 | 0.0004 | 0.0028 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0035 | 0.0045 | 0.3291 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0058 | 0.0514 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0082 | 0.027 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0051 | 0.0086 | 0.4343 |
Mycobacterium ulcerans | beta-lactamase | 0.0072 | 0.0137 | 0.0228 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0026 | 0.0023 | 0.0063 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0073 | 0.0141 | 0.0456 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0084 | 0.0168 | 0.0556 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0061 | 0.011 | 0.0985 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0172 | 0.039 | 0.6699 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0051 | 0.0086 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.004 | 0.0058 | 0.0178 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0263 | 0.0617 | 0.5505 |
Trichomonas vaginalis | helicase, putative | 0.0026 | 0.0022 | 0.0285 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0015 | 0.0024 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0019 | 0.0004 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0243 | 0.2166 |
Schistosoma mansoni | hypothetical protein | 0.0121 | 0.026 | 0.0863 |
Schistosoma mansoni | nuclear hormone receptor | 0.0019 | 0.0004 | 0.0011 |
Brugia malayi | Muscleblind-like protein | 0.0155 | 0.0347 | 0.3089 |
Onchocerca volvulus | Bile acid receptor homolog | 0.004 | 0.0058 | 0.0975 |
Schistosoma mansoni | hypothetical protein | 0.0841 | 0.2071 | 0.6885 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0035 | 0.0045 | 0.0592 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0192 | 0.3054 |
Trichomonas vaginalis | heat shock protein, putative | 0.0051 | 0.0086 | 0.1326 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0072 | 0.0137 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0032 | 0.0091 |
Echinococcus multilocularis | protein patched | 0.0125 | 0.0272 | 0.0268 |
Schistosoma mansoni | alpha-glucosidase | 0.0143 | 0.0315 | 0.1046 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0004 | 0.0011 |
Echinococcus multilocularis | dnaJ subfamily B | 0.1213 | 0.3008 | 0.3006 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Schistosoma mansoni | hypothetical protein | 0.0841 | 0.2071 | 0.6885 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0137 | 0.1224 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0137 | 0.709 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.004 | 0.0058 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0005 | 0.0043 |
Brugia malayi | conserved hypotetical protein | 0.0019 | 0.0004 | 0.0028 |
Trypanosoma brucei | heat shock protein, putative | 0.0065 | 0.0119 | 0.6111 |
Echinococcus multilocularis | tumor protein p63 | 0.0341 | 0.0814 | 0.081 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0015 | 0.0024 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0137 | 0.0228 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.004 | 0.0058 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0058 | 0.0514 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.003 |
Schistosoma mansoni | alpha-glucosidase | 0.0143 | 0.0315 | 0.1046 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0192 | 0.3054 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0015 | 0.0024 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0015 | 0.0024 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0292 | 0.0691 | 0.6165 |
Schistosoma mansoni | myst-related protein | 0.0019 | 0.0005 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.001 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0305 | 0.0724 | 0.646 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0263 | 0.0617 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0305 | 0.0724 | 0.6457 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0065 | 0.0119 | 0.6111 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0042 | 0.0062 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.004 | 0.0058 | 0.0514 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0045 | 0.2171 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.004 | 0.0058 | 0.0975 |
Echinococcus multilocularis | endoplasmin | 0.0051 | 0.0086 | 0.0082 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0236 | 0.0549 | 0.1814 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0071 | 0.0136 | 0.044 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Schistosoma mansoni | hypothetical protein | 0.0121 | 0.026 | 0.0863 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0172 | 0.039 | 0.6291 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0137 | 0.0228 |
Brugia malayi | Hsp90 protein | 0.0026 | 0.0023 | 0.0197 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0137 | 0.1224 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0071 | 0.0136 | 0.0132 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.004 | 0.0058 | 0.0178 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.004 | 0.0058 | 0.0514 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.0001 | 0.0008 |
Trichomonas vaginalis | heat shock protein, putative | 0.0051 | 0.0086 | 0.1326 |
Trypanosoma brucei | polo-like protein kinase | 0.0093 | 0.0192 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0019 | 0.0005 | 0.0013 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0305 | 0.0724 | 0.646 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0137 | 0.1224 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.004 | 0.0058 | 0.0178 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0065 | 0.0119 | 0.6111 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0019 | 0.0004 | 0.0028 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0093 | 0.0192 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Brugia malayi | hypothetical protein | 0.0463 | 0.112 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.004 | 0.0058 | 0.0514 |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0137 | 0.0226 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0137 | 0.0228 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0041 | 0.0133 |
Echinococcus granulosus | dnaJ subfamily C 6 | 0.0062 | 0.0113 | 0.0363 |
Onchocerca volvulus | 0.0096 | 0.0198 | 0.3385 | |
Schistosoma mansoni | patched 1 | 0.0125 | 0.0272 | 0.0901 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0005 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.0194 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0182 | 0.0413 | 0.6672 |
Schistosoma mansoni | nuclear receptor | 0.0019 | 0.0004 | 0.0011 |
Echinococcus multilocularis | heat shock protein 90 | 0.0065 | 0.0119 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0137 | 0.1224 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0296 | 0.0702 | 0.2333 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0208 | 0.0481 | 0.4288 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.004 | 0.0058 | 0.0506 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0041 | 0.2968 |
Brugia malayi | CXXC zinc finger family protein | 0.0115 | 0.0246 | 0.2187 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0125 | 0.0272 | 0.2425 |
Echinococcus granulosus | expressed conserved protein | 0.0274 | 0.0646 | 0.2138 |
Trypanosoma brucei | ISWI complex protein | 0.0045 | 0.0071 | 0.3529 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0051 | 0.0086 | 0.4343 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0015 | 0.0024 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0107 | 0.0225 | 0.0734 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0137 | 0.709 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.004 | 0.0058 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.001 | 0.0088 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0072 | 0.0137 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0019 | 0.0004 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Trichomonas vaginalis | esterase, putative | 0.0072 | 0.0137 | 0.2165 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0137 | 0.0454 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0022 | 0.0285 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.003 | 0.0031 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Brugia malayi | Bromodomain containing protein | 0.0114 | 0.0242 | 0.2155 |
Trypanosoma cruzi | ISWI complex protein | 0.0045 | 0.0071 | 0.3529 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0136 | 0.0451 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0015 | 0.0149 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0125 | 0.0272 | 0.089 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0136 | 0.1919 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0093 | 0.0192 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0258 | 0.2302 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.004 | 0.0058 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0137 | 0.1224 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0015 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.0347 | 0.3095 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0096 | 0.0199 | 0.1778 |
Mycobacterium ulcerans | pantoate--beta-alanine ligase | 0.2412 | 0.6025 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0034 | 0.1585 |
Brugia malayi | nuclear receptor RXR | 0.0021 | 0.001 | 0.008 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.0199 | 0.066 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0093 | 0.0192 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0015 | 0.0132 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0166 | 0.0373 | 0.0369 |
Onchocerca volvulus | 0.0072 | 0.0137 | 0.2346 | |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0049 | 0.0724 |
Brugia malayi | ecdysone receptor | 0.0019 | 0.0004 | 0.0028 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0049 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Trypanosoma brucei | heat shock protein, putative | 0.0065 | 0.0119 | 0.6111 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0096 | 0.0199 | 0.0649 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0263 | 0.0617 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Schistosoma mansoni | bromodomain containing protein | 0.0194 | 0.0445 | 0.1477 |
Echinococcus granulosus | transcription factor btf3 | 0.0035 | 0.0045 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.0481 | 0.4293 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0084 | 0.0168 | 0.0164 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0 | 0.5 |
Onchocerca volvulus | 0.0019 | 0.0004 | 0.0055 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0022 | 0.0285 |
Echinococcus granulosus | FTZ F1 alpha | 0.004 | 0.0058 | 0.0178 |
Echinococcus multilocularis | heat shock protein | 0.0065 | 0.0119 | 0.0115 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0137 | 0.0443 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.004 | 0.0058 | 0.0189 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0096 | 0.0199 | 0.1771 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0125 | 0.0272 | 0.0268 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0084 | 0.0168 | 0.0556 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0192 | 0.3054 |
Trypanosoma brucei | heat shock protein, putative | 0.0065 | 0.0119 | 0.6111 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0049 | 0.0647 |
Toxoplasma gondii | NAC domain-containing protein | 0.0035 | 0.0045 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.001 | 0.003 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0005 | 0.0007 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0072 | 0.0137 | 0.0228 |
Echinococcus granulosus | tumor protein p63 | 0.0341 | 0.0814 | 0.2696 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0166 | 0.0373 | 0.3332 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0005 | 0.0007 |
Giardia lamblia | Grp94/Hsp90 | 0.0051 | 0.0086 | 0.4343 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0058 | 0.0514 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0065 | 0.0119 | 0.6111 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0019 | 0.0004 | 0.0011 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0047 | 0.0074 | 0.1137 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0172 | 0.039 | 0.6291 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.004 | 0.0058 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.0001 | 0.0008 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0026 | 0.0023 | 0.1932 |
Onchocerca volvulus | 0.0072 | 0.0137 | 0.2346 | |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0168 | 0.1499 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0049 | 0.0724 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0031 | 0.0034 | 0.2875 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0065 | 0.0119 | 0.1666 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0031 | 0.0034 | 0.0057 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0037 | 0.0049 | 0.0045 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0125 | 0.0272 | 0.436 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.004 | 0.0058 | 0.0053 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0065 | 0.0119 | 0.6111 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.004 | 0.0058 | 0.0514 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.025 | 0.2233 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0137 | 0.0228 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.01 |
Schistosoma mansoni | myst-related protein | 0.0019 | 0.0005 | 0.0013 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0049 | 0.2372 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0045 | 0.0663 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0137 | 0.0454 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.004 | 0.0058 | 0.0506 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0071 | 0.0136 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0137 | 0.1224 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Schistosoma mansoni | endoplasmin | 0.0065 | 0.0119 | 0.0393 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0305 | 0.0724 | 0.6457 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0192 | 0.3054 |
Plasmodium vivax | heat shock protein 86, putative | 0.0065 | 0.0119 | 0.8666 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0031 | 0.0034 | 0.1585 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.003 | 0.0031 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0065 | 0.0119 | 0.0196 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0038 | 0.0052 | 0.2554 |
Schistosoma mansoni | kinase | 0.0048 | 0.0077 | 0.0254 |
Plasmodium falciparum | endoplasmin, putative | 0.004 | 0.0056 | 0.4716 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0015 | 0.0123 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.0111 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0045 | 0.0663 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0199 | 0.1778 |
Onchocerca volvulus | 0.0019 | 0.0004 | 0.0055 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0172 | 0.039 | 0.6291 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0291 | 0.2598 |
Brugia malayi | DnaJ domain containing protein | 0.0062 | 0.0113 | 0.1002 |
Brugia malayi | nuclear hormone receptor | 0.004 | 0.0058 | 0.0506 |
Brugia malayi | ecdysteroid receptor | 0.004 | 0.0058 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0258 | 0.2302 |
Brugia malayi | Isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.0297 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0096 | 0.0199 | 0.0195 |
Brugia malayi | PHD-finger family protein | 0.008 | 0.0159 | 0.141 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0049 | 0.0724 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.004 | 0.0058 | 0.0053 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.003 | 0.0031 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Onchocerca volvulus | 0.005 | 0.0082 | 0.1395 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0022 | 0.0285 |
Echinococcus multilocularis | expressed conserved protein | 0.0274 | 0.0646 | 0.0643 |
Giardia lamblia | Kinase, PLK | 0.0093 | 0.0192 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0045 | 0.0592 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0137 | 0.1217 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0005 | 0.0012 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0084 | 0.0168 | 0.0545 |
Plasmodium falciparum | zinc finger protein, putative | 0.0019 | 0.0005 | 0.0402 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0058 | 0.0514 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0015 | 0.0149 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.004 | 0.0058 | 0.0975 |
Brugia malayi | nuclear receptor RXR | 0.0019 | 0.0004 | 0.0028 |
Onchocerca volvulus | 0.004 | 0.0058 | 0.0975 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Brugia malayi | Bromodomain containing protein | 0.0229 | 0.0533 | 0.4749 |
Loa Loa (eye worm) | DnaJ domain-containing protein | 0.0062 | 0.0113 | 0.101 |
Onchocerca volvulus | 0.0023 | 0.0015 | 0.0238 | |
Trichomonas vaginalis | protein kinase inhibitor, putative | 0.0062 | 0.0113 | 0.1773 |
Trichomonas vaginalis | heat shock protein, putative | 0.004 | 0.0056 | 0.0841 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.004 | 0.0058 | 0.0053 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0041 | 0.0133 |
Schistosoma mansoni | zinc finger protein | 0.0065 | 0.0119 | 0.0393 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.004 | 0.0058 | 0.0053 |
Echinococcus multilocularis | geminin | 0.0841 | 0.2071 | 0.2068 |
Echinococcus multilocularis | GPCR, family 2 | 0.0096 | 0.0199 | 0.0195 |
Brugia malayi | isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.0297 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0184 | 0.0418 | 0.1379 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0072 | 0.0137 | 0.0228 |
Schistosoma mansoni | heat shock protein | 0.0065 | 0.0119 | 0.0393 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0041 | 0.0355 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0263 | 0.0617 | 0.5509 |
Onchocerca volvulus | 0.0034 | 0.0041 | 0.0685 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0192 | 0.3054 |
Brugia malayi | hypothetical protein | 0.012 | 0.0258 | 0.2295 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0051 | 0.0086 | 0.4343 |
Schistosoma mansoni | nuclear receptor | 0.0019 | 0.0004 | 0.0011 |
Brugia malayi | CHE-14 protein | 0.0125 | 0.0272 | 0.2418 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0115 | 0.0246 | 0.2193 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0192 | 0.3054 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0022 | 0.0285 |
Echinococcus multilocularis | transcription factor btf3 | 0.0035 | 0.0045 | 0.0041 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0065 | 0.0119 | 0.6111 |
Brugia malayi | steroid hormone receptor | 0.004 | 0.0058 | 0.0506 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0073 | 0.0141 | 0.0137 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0417 | 0.1006 | 0.3336 |
Loa Loa (eye worm) | DR-78 | 0.0019 | 0.0004 | 0.0037 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0172 | 0.039 | 0.6291 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.0199 | 0.066 |
Brugia malayi | beta-NAC-like protein | 0.0035 | 0.0045 | 0.0395 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0459 | 0.1111 | 0.1845 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.003 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0051 | 0.0086 | 0.4343 |
Loa Loa (eye worm) | hypothetical protein | 0.0463 | 0.112 | 1 |
Trypanosoma cruzi | heat shock protein, putative | 0.0026 | 0.0023 | 0.0986 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0463 | 0.112 | 0.3715 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0034 | 0.1585 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0058 | 0.0514 |
Echinococcus granulosus | dnaJ subfamily B | 0.1213 | 0.3008 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.001 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0208 | 0.0481 | 0.1596 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0096 | 0.0199 | 0.1771 |
Trichomonas vaginalis | set domain proteins, putative | 0.0249 | 0.0582 | 0.942 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.0305 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.004 | 0.0058 | 0.0506 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0051 | 0.0084 | 0.0276 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0041 | 0.0066 |
Echinococcus multilocularis | muscleblind protein | 0.0155 | 0.0347 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0026 | 0.0023 | 0.1932 |
Onchocerca volvulus | 0.0249 | 0.0582 | 1 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0072 | 0.0137 | 0.0204 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0136 | 0.1919 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0463 | 0.112 | 0.1117 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0051 | 0.0084 | 0.0276 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0137 | 0.709 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0065 | 0.0119 | 0.6111 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0015 | 0.0149 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0292 | 0.0691 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0226 | 0.0525 | 0.087 |
Trypanosoma brucei | heat shock protein, putative | 0.0065 | 0.0119 | 0.6111 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0166 | 0.0373 | 0.1229 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0026 | 0.0023 | 0.0205 |
Echinococcus multilocularis | cpg binding protein | 0.0127 | 0.0276 | 0.0272 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.004 | 0.0058 | 0.0506 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.004 | 0.0058 | 0.0189 |
Plasmodium vivax | endoplasmin, putative | 0.0065 | 0.0119 | 0.8666 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0049 | 0.0724 |
Brugia malayi | heat shock protein 90 | 0.0065 | 0.0119 | 0.1054 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0019 | 0.0004 | 0.0028 |
Plasmodium vivax | heat shock protein 90, putative | 0.0026 | 0.0023 | 0.1675 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0015 | 0.0024 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.004 | 0.0058 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.0347 | 0.3095 |
Onchocerca volvulus | 0.0115 | 0.0246 | 0.4215 | |
Schistosoma mansoni | survival motor neuron protein | 0.0094 | 0.0194 | 0.0642 |
Loa Loa (eye worm) | histone methyltransferase | 0.0037 | 0.0049 | 0.0435 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0049 | 0.0436 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0021 | 0.001 | 0.003 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0049 | 0.2372 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0049 | 0.0149 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0137 | 0.2165 |
Schistosoma mansoni | transcription factor btf3 | 0.0035 | 0.0045 | 0.0148 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0019 | 0.0004 | 0.0037 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.025 | 0.2233 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0026 | 0.0023 | 0.0037 |
Plasmodium falciparum | heat shock protein 90 | 0.0065 | 0.0119 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.004 | 0.0058 | 0.0189 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0166 | 0.0373 | 0.0369 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.004 | 0.0058 | 0.0178 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0005 | 0.038 |
Onchocerca volvulus | 0.0094 | 0.0194 | 0.3321 | |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0073 | 0.0141 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0058 | 0.0514 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.004 | 0.0058 | 0.0506 |
Trypanosoma brucei | heat shock protein, putative | 0.0065 | 0.0119 | 0.6111 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.004 | 0.0058 | 0.0506 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0019 | 0.0004 | 0.0011 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0035 | 0.0045 | 0.2171 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0049 | 0.2372 |
Brugia malayi | hypothetical protein | 0.0021 | 0.001 | 0.008 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.0258 | 0.4424 |
Brugia malayi | nuclear hormone receptor | 0.0019 | 0.0004 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0021 | 0.001 | 0.008 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.004 | 0.0058 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0061 | 0.011 | 0.0364 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0065 | 0.0119 | 0.6111 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Trypanosoma cruzi | ISWI complex protein | 0.0045 | 0.0071 | 0.3529 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0094 | 0.0194 | 0.1723 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0292 | 0.0691 | 0.2286 |
Schistosoma mansoni | nuclear hormone receptor | 0.0019 | 0.0004 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Echinococcus granulosus | heat shock protein 90 | 0.0065 | 0.0119 | 0.0382 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0026 | 0.0022 | 0.0285 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0137 | 0.1224 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.004 | 0.0058 | 0.0189 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0049 | 0.0724 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.0258 | 0.4424 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.004 | 0.0058 | 0.0514 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0047 | 0.0074 | 0.1137 |
Echinococcus multilocularis | FTZ F1 alpha | 0.004 | 0.0058 | 0.0053 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0065 | 0.0119 | 0.6111 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.004 | 0.0058 | 0.0189 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0051 | 0.0086 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0026 | 0.0022 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0015 | 0.0132 |
Brugia malayi | Pre-SET motif family protein | 0.0219 | 0.0507 | 0.4517 |
Plasmodium vivax | patched family protein, putative | 0.0018 | 0.0001 | 0.0069 |
Echinococcus granulosus | zinc finger protein | 0.0065 | 0.0119 | 0.0382 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0263 | 0.0617 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.004 | 0.0058 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0065 | 0.0119 | 0.1666 |
Brugia malayi | beta-lactamase | 0.0072 | 0.0137 | 0.1217 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.0199 | 0.066 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0022 | 0.0285 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.004 | 0.0058 | 0.0178 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0182 | 0.0413 | 0.6672 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.004 | 0.0058 | 0.0189 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.004 | 0.0058 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.021 | 0.0484 | 0.4321 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0272 | 0.2425 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0049 | 0.0724 |
Schistosoma mansoni | heat shock protein | 0.0065 | 0.0119 | 0.0393 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0072 | 0.0137 | 0.0228 |
Schistosoma mansoni | hypothetical protein | 0.0121 | 0.026 | 0.0863 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0051 | 0.0086 | 0.0272 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0051 | 0.0084 | 0.008 |
Trichomonas vaginalis | heat shock protein, putative | 0.0051 | 0.0086 | 0.1326 |
Entamoeba histolytica | hypothetical protein | 0.0019 | 0.0005 | 0.0004 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0136 | 0.1919 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.0001 | 0.0008 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0136 | 0.1919 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0049 | 0.2372 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0026 | 0.0023 | 0.0379 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.001 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0026 | 0.0023 | 0.0037 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0035 | 0.0045 | 0.3798 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.001 | 0.008 |
Treponema pallidum | heat shock protein 90 | 0.0051 | 0.0086 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0005 | 0.0001 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0019 | 0.0004 | 0.0055 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0137 | 0.2165 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0137 | 0.709 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0015 | 0.0024 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0022 | 0.0285 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0037 | 0.0049 | 0.0149 |
Echinococcus granulosus | heat shock protein | 0.0065 | 0.0119 | 0.0382 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0015 | 0.0547 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0049 | 0.0724 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.003 | 0.0031 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0026 | 0.0023 | 0.0269 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0045 | 0.0663 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.003 | 0.0031 | 0.0101 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0236 | 0.0549 | 0.0545 |
Trypanosoma brucei | heat shock protein, putative | 0.0065 | 0.0119 | 0.6111 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0263 | 0.0617 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0172 | 0.039 | 0.6291 |
Schistosoma mansoni | thyroid hormone receptor | 0.004 | 0.0058 | 0.0189 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0021 | 0.001 | 0.0006 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0093 | 0.0192 | 0.1704 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0019 | 0.0004 | 0.0037 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0172 | 0.039 | 0.6291 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0263 | 0.0617 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0019 | 0.0004 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.001 | 0.0088 |
Trichomonas vaginalis | heat shock protein, putative | 0.0065 | 0.0119 | 0.1867 |
Loa Loa (eye worm) | ICD-1 protein | 0.0035 | 0.0045 | 0.0403 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.0192 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0058 | 0.0514 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0107 | 0.0225 | 0.022 |
Brugia malayi | tailless protein | 0.0019 | 0.0004 | 0.0028 |
Echinococcus multilocularis | dnaJ subfamily C 6 | 0.0062 | 0.0113 | 0.0109 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0065 | 0.0119 | 0.0196 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.004 | 0.0058 | 0.0506 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0005 | 0.0006 |
Schistosoma mansoni | zinc finger protein | 0.0045 | 0.0071 | 0.0232 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0022 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0.0034 | 0.1585 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.003 |
Brugia malayi | Endoplasmin precursor | 0.0065 | 0.0119 | 0.1054 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0065 | 0.0119 | 0.6111 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0.0034 | 0.0055 |
Schistosoma mansoni | heat shock protein | 0.0026 | 0.0023 | 0.0074 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0137 | 0.1217 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0219 | 0.0507 | 0.4521 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0005 | 0.0032 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0031 | 0.0034 | 0.2491 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0015 | 0.0024 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0093 | 0.0192 | 0.3284 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0015 | 0.0024 |
Echinococcus multilocularis | zinc finger protein | 0.0065 | 0.0119 | 0.0115 |
Plasmodium falciparum | lipid/sterol:H+ symporter | 0.0018 | 0.0001 | 0.0079 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.004 | 0.0058 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0137 | 0.1224 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0001 | 0.0008 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0049 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.0691 | 0.6168 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0004 | 0.0028 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0155 | 0.0347 | 0.0343 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0184 | 0.0418 | 0.0414 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0041 | 0.0037 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0072 | 0.0137 | 0.0228 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0166 | 0.0373 | 0.3326 |
Trypanosoma brucei | heat shock protein, putative | 0.0065 | 0.0119 | 0.6111 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0023 | 0.0301 |
Brugia malayi | hypothetical protein | 0.0071 | 0.0136 | 0.1209 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0058 | 0.0514 |
Brugia malayi | nuclear receptor NHR-67 | 0.0019 | 0.0004 | 0.0028 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0019 | 0.0004 | 0.0028 |
Schistosoma mansoni | hypothetical protein | 0.1213 | 0.3008 | 1 |
Toxoplasma gondii | pantoate-beta-alanine ligase | 0.2412 | 0.6025 | 1 |
Loa Loa (eye worm) | patched family protein | 0.0018 | 0.0001 | 0.0008 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.004 | 0.0058 | 0.0053 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0096 | 0.0199 | 0.0195 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0137 | 0.2165 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0015 | 0.0132 |
Brugia malayi | nuclear receptor NHR-88 | 0.004 | 0.0058 | 0.0506 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0137 | 0.2165 |
Trichomonas vaginalis | endoplasmin, putative | 0.004 | 0.0056 | 0.0841 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.004 | 0.0058 | 0.0189 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0026 | 0.0023 | 0.0986 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0137 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0051 | 0.0086 | 0.0082 |
Leishmania major | heat shock protein 83-1 | 0.0065 | 0.0119 | 0.6111 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0019 | 0.0004 | 0.0037 |
Echinococcus granulosus | GPCR family 2 | 0.0096 | 0.0199 | 0.0649 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0096 | 0.0199 | 0.0649 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0021 | 0.001 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.004 | 0.0058 | 0.0506 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.004 | 0.0058 | 0.0514 |
Mycobacterium ulcerans | lipase LipD | 0.0072 | 0.0137 | 0.0228 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.004 | 0.0058 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0004 | 0.0037 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.0192 | 0.3054 |
Schistosoma mansoni | cpg binding protein | 0.0115 | 0.0246 | 0.0814 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0172 | 0.039 | 0.6291 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ILS (functional) | = 13.8 % | Percent increase in life span at dose 65 mg/kg/day in 10 mice implanted with P388 leukemia cell line | ChEMBL. | 4020828 |
ILS (functional) | = 23 % | Percent increase in life span at dose 55 mg/kg/day in 10 mice implanted with P388 leukemia cell line | ChEMBL. | 4020828 |
ILS (functional) | = 26 % | Percent increase in life span at dose 60 mg/kg/day in 10 mice implanted with P388 leukemia cell line | ChEMBL. | 4020828 |
ILS (functional) | = 26.7 % | Percent increase in life span at dose 70 mg/kg/day in 10 mice implanted with P388 leukemia cell line | ChEMBL. | 4020828 |
ILS (functional) | = 27.6 % | Percent increase in life span at dose 80 mg/kg/day in 10 mice implanted with P388 leukemia cell line | ChEMBL. | 4020828 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.