Detailed information for compound 1614814

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.264 | Formula: C17H22BrNO5
  • H donors: 2 H acceptors: 3 LogP: 1.81 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H](c1ccccc1)C(=O)O[C@@H]1C[C@H]2[C@@H]3[C@H]([C@H](C1)[N+]2([O-])C)O3.Br
  • InChi: 1S/C17H21NO5.BrH/c1-18(21)13-7-11(8-14(18)16-15(13)23-16)22-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13+,14+,15-,16+,18?;/m1./s1
  • InChiKey: MGNNYKWRWHQLCR-RZSRPCEGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0061 0.0147 0.0374
Loa Loa (eye worm) hypothetical protein 0.0038 0.0071 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Leishmania major trypanothione reductase 0.0038 0.007 0.142
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0031 0.0031
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Echinococcus granulosus cpg binding protein 0.0067 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0037 0.0069 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0046 0.0046
Brugia malayi G protein-coupled receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Echinococcus multilocularis serotonin receptor 0.0157 0.0458 0.0458
Brugia malayi Smad1 0.0035 0.006 0.0073
Onchocerca volvulus 0.0038 0.0072 0.0183
Schistosoma mansoni adenoreceptor 0.0022 0.0018 0.0018
Brugia malayi Calcitonin receptor-like protein seb-1 0.0223 0.0672 0.0817
Loa Loa (eye worm) nuclear factor I 0.0019 0.001 0.0012
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0093 0.2071
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0012
Plasmodium falciparum glutathione reductase 0.0038 0.007 0.3284
Loa Loa (eye worm) hypothetical protein 0.0056 0.0131 0.016
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Trichomonas vaginalis glutaminase, putative 0.0636 0.2016 0.4972
Brugia malayi Dopamine receptor protein 2 0.0022 0.0018 0.0021
Schistosoma mansoni biogenic amine (5HT) receptor 0.0157 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Onchocerca volvulus 0.0022 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0047 0.0101 0.0123
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6529
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0728 0.0728
Echinococcus granulosus tar DNA binding protein 0.0063 0.0153 0.0153
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0063 0.0063
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0084 0.0221 0.0269
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Schistosoma mansoni hypothetical protein 0.0774 0.2465 0.2465
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0093 0.0104
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0076 0.0061
Echinococcus granulosus X box binding protein 1 0.0332 0.1029 0.1029
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.1854
Loa Loa (eye worm) hypothetical protein 0.0157 0.0458 0.0557
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0018 0.0018
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.0059 0.0059
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2151
Schistosoma mansoni hypothetical protein 0.0469 0.1472 0.1472
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0072 0.0012
Onchocerca volvulus 0.0022 0.0018 0.0046
Brugia malayi hypothetical protein 0.0019 0.0008 0.001
Schistosoma mansoni survival motor neuron protein 0.0106 0.0292 0.0292
Onchocerca volvulus Huntingtin homolog 0.0425 0.1331 0.3383
Brugia malayi latrophilin 2 splice variant baaae 0.0152 0.0443 0.0539
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.0059 0.0072
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0016 0.0257
Schistosoma mansoni hypothetical protein 0.0106 0.0292 0.0292
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0072 0.0012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0059 0.0138 0.0138
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0221 0.0488
Brugia malayi isocitrate dehydrogenase 0.0055 0.0126 0.0153
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2391
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0063 0.0063
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.0528 0.0642
Brugia malayi Intermediate filament tail domain containing protein 0.0122 0.0343 0.0418
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.004 0.0077 0.0062
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.035 0.1087 0.2761
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.0127
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0049 0.0108 0.0274
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.0059 0.0072
Brugia malayi hypothetical protein 0.0018 0.0006 0.0008
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Brugia malayi glutathione reductase 0.0038 0.007 0.0085
Trichomonas vaginalis set domain proteins, putative 0.0231 0.07 0.1684
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0076 0.0093
Onchocerca volvulus 0.0034 0.0059 0.015
Treponema pallidum fructose-bisphosphate aldolase 0.1254 0.4028 1
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.007 0.1628
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0018 0.0018
Echinococcus granulosus FTZ F1 alpha 0.0034 0.0059 0.0059
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0153 0.0186
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.0059 0.0059
Brugia malayi TAR-binding protein 0.0063 0.0153 0.0186
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi ecdysteroid receptor 0.0034 0.0059 0.0072
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0519 0.1637 0.1991
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0613 0.1941 0.9614
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Brugia malayi larval opioid receptor 0.0022 0.0018 0.0021
Schistosoma mansoni hypothetical protein 0.002 0.0014 0.0014
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.0059 0.0072
Loa Loa (eye worm) inositol-1 0.0043 0.0086 0.0105
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0072 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0335 0.8719
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0018 0.0018
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0042 0.0662
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0055 0.0126 0.0301
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.0742 0.3596
Brugia malayi Melatonin receptor type 1A 0.0022 0.0018 0.0021
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0042 0.1043
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0108 0.0108
Loa Loa (eye worm) glutaminase 2 0.0636 0.2016 0.2452
Brugia malayi N-terminal motif family protein 0.0179 0.053 0.0645
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0086 0.0086
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.007 0.0177 0.0177
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0072 0.0012
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0257 0.1003
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0018 0.0018
Brugia malayi Pre-SET motif family protein 0.003 0.0046 0.0056
Echinococcus granulosus neuropeptide receptor 0.0022 0.0018 0.0018
Toxoplasma gondii isocitrate dehydrogenase 0.0055 0.0126 0.2968
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.0127
Loa Loa (eye worm) hypothetical protein 0.0425 0.1331 0.1619
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0055 0.0126 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0226 0.0836
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0052 0.1193
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Schistosoma mansoni coup transcription factor 0.0034 0.0059 0.0059
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0018 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0069 0.0069
Echinococcus multilocularis ubiquitin specific protease 41 0.0084 0.0221 0.0221
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0335 1
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0613 0.1941 1
Brugia malayi hypothetical protein 0.0018 0.0006 0.0008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0018 0.0018
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.006 0.006
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0055 0.0126 0.0126
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0018 0.0018
Schistosoma mansoni alpha glucosidase 0.004 0.0076 0.0076
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0728 0.0728
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0179 0.053 0.0645
Trichomonas vaginalis esterase, putative 0.0038 0.0072 0.0114
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0071 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Loa Loa (eye worm) histone methyltransferase 0.002 0.0013 0.0015
Brugia malayi hypothetical protein 0.0425 0.1331 0.1619
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Leishmania major hypothetical protein, conserved 0.0029 0.0042 0.0662
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.0059 0.0072
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.004 0.0077 0.4137
Brugia malayi MH2 domain containing protein 0.0035 0.006 0.0073
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Brugia malayi Thioredoxin reductase 0.0038 0.007 0.0085
Echinococcus granulosus GPCR family 2 0.007 0.0177 0.0177
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0335 0.0335
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1254 0.4028 1
Brugia malayi MH1 domain containing protein 0.0035 0.006 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.0059 0.0072
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0221 0.0221
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.1225 0.3935 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0034 0.0059 0.0059
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Onchocerca volvulus 0.0022 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.2543 0.8222 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0086 0.015
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.015 0.015
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0613 0.1941 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.0059 0.0072
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.0059 0.0059
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0072 0.0114
Brugia malayi CXXC zinc finger family protein 0.0061 0.0147 0.0179
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0153 0.0186
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0728 0.0728
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0018 0.0018
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0223 0.0672 0.0817
Echinococcus granulosus intermediate filament protein 0.0122 0.0343 0.0343
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0004 0.0005
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni cpg binding protein 0.0067 0.0165 0.0165
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0018 0.0021
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.0059 0.0059
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Brugia malayi G-protein coupled receptor 0.0022 0.0018 0.0021
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0022
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.0059 0.0072
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0055 0.0126 0.3607
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0018 0.0018
Echinococcus granulosus survival motor neuron protein 1 0.0519 0.1637 0.1637
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.0059 0.0072
Echinococcus granulosus smad 0.0035 0.006 0.006
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0046 0.0046
Schistosoma mansoni inositol monophosphatase 0.0043 0.0086 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0093 0.0093
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0221 0.0221
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0059 0.0059
Schistosoma mansoni lamin 0.0122 0.0343 0.0343
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.006 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0042 0.004
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0052 0.1193
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0072 0.0072
Brugia malayi hypothetical protein 0.0029 0.0042 0.0051
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0018 0.0018
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0018 0.0018
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0018 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0059 0.0072
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni myosin xvIII 0.0022 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.0059 0.0072
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0084 0.0221 0.0426
Onchocerca volvulus 0.0122 0.0343 0.0873
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis thyroid hormone receptor alpha 0.0034 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0093 0.2375
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0093 0.0113
Brugia malayi hypothetical protein 0.2543 0.8222 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni inositol monophosphatase 0.0043 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0006 0.0006
Echinococcus granulosus neuropeptide receptor 0.0022 0.0018 0.0018
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0034 0.0059 0.0059
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0335 0.0407
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0052 0.0937
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0153 0.0186
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi GnHR receptor homolog 0.0022 0.0018 0.0021
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0052 0.0937
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.004 0.0077 0.4137
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0072 0.0114
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0055 0.0126 0.0126
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0489 0.1537 0.187
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0018 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.006 0.0073
Brugia malayi AKH receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0055 0.0126 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0093 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Echinococcus granulosus lamin 0.0122 0.0343 0.0343
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0257 0.0993
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0226 0.0836
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0212
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0059 0.0059
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0018 0.0021
Loa Loa (eye worm) latrophilin receptor protein 2 0.007 0.0177 0.0215
Brugia malayi hypothetical protein 0.035 0.1087 0.1321
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0059 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0019
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0335 0.0335
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1254 0.4028 1
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0018 0.0022
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0059 0.0072
Echinococcus multilocularis muscleblind protein 0.0489 0.1537 0.1537
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.006 0.0073
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0122 0.0343 0.0418
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi MH1 domain containing protein 0.0035 0.006 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0018 0.0018
Schistosoma mansoni smad 0.0035 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0108 0.0131
Brugia malayi follicle stimulating hormone receptor 0.0022 0.0018 0.0021
Echinococcus granulosus neuropeptide s receptor 0.1618 0.5213 0.5213
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0381 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0507 0.1598 0.1943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis Smad4 0.0035 0.006 0.006
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0093 0.2071
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.004 0.0077 0.0077
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0018 0.0021
Schistosoma mansoni alpha-glucosidase 0.0154 0.0447 0.0447
Echinococcus multilocularis neuropeptide receptor A26 0.1618 0.5213 0.5213
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0018 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0157 0.0458 0.0458
Onchocerca volvulus 0.0022 0.0018 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0101 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.0059 0.0072
Loa Loa (eye worm) intermediate filament protein 0.0122 0.0343 0.0418
Echinococcus multilocularis dnaJ subfamily B 0.0469 0.1472 0.1472
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0018 0.0045
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0147 0.0179
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0093 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0059 0.0072
Brugia malayi Serotonin receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0221 0.0488
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0018 0.0018
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0052 0.5
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0059 0.0072
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0018 0.0018
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0335 0.1408
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0084 0.0221 0.0221
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.0059 0.0059
Schistosoma mansoni cpg binding protein 0.0061 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0022
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0223 0.0672 0.0817
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0012
Toxoplasma gondii ABC1 family protein 0.0038 0.0072 0.1482
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.0059 0.015
Echinococcus multilocularis zinc finger protein 0.0023 0.0022 0.0022
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0071 0.0071
Brugia malayi hypothetical protein 0.0037 0.0069 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0072 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Trypanosoma brucei trypanothione reductase 0.0038 0.007 0.1885
Schistosoma mansoni glutaminase 0.0636 0.2016 0.2016
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0056 0.1042
Loa Loa (eye worm) transcription factor SMAD2 0.0507 0.1598 0.1943
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0018 0.0021
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0063 0.1437
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0018 0.0018
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0157 0.0458 0.0557
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.053 0.1348
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0076 0.0061
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0084 0.0221 0.0426
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0042 0.0759
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0018 0.0018
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0055 0.0126 0.3404
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0072 0.0001
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Brugia malayi ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0226 0.0836
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0038 0.0038
Brugia malayi beta-lactamase 0.0038 0.0072 0.0087
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0119 0.0336 0.0409
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0076 0.1603
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Plasmodium vivax glutathione reductase, putative 0.0038 0.007 0.3284
Giardia lamblia Fructose-bisphosphate aldolase 0.1254 0.4028 1
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Schistosoma mansoni zinc finger protein 0.0023 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0335 0.0407
Echinococcus multilocularis somatostatin receptor 0.0022 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Mycobacterium ulcerans glutaminase 0.0636 0.2016 1
Brugia malayi RE15519p 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0051
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi neuropeptide F receptor 0.0022 0.0018 0.0021
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0072 0.0072
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0059 0.0059
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0381 0.0381
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0489 0.1537 0.187
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0018 0.0021
Brugia malayi beta-lactamase family protein 0.0038 0.0072 0.0087
Echinococcus multilocularis serotonin receptor 0.0157 0.0458 0.0458
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0084 0.0221 0.0269
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Echinococcus multilocularis neuropeptide s receptor 0.1618 0.5213 0.5213
Echinococcus granulosus serotonin receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Toxoplasma gondii thioredoxin reductase 0.0038 0.007 0.142
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.0059 0.0072
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0257 0.1003
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0052 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0072 0.0072
Brugia malayi MH2 domain containing protein 0.0035 0.006 0.0073
Echinococcus granulosus ubiquitin specific protease 41 0.0084 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Mycobacterium tuberculosis Probable reductase 0.0086 0.0226 0.0836
Brugia malayi Dopamine receptor protein 1 0.0022 0.0018 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Brugia malayi G-protein coupled receptor 0.0022 0.0018 0.0021
Echinococcus granulosus geminin 0.0774 0.2465 0.2465
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0022 0.0018 0.0018
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0006 0.0006
Schistosoma mansoni cpg binding protein 0.0067 0.0165 0.0165
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0018 0.0018
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0046 0.0772
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0086 0.5
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0221 0.0221
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.004 0.0077 0.1616
Onchocerca volvulus 0.0022 0.0018 0.0045
Loa Loa (eye worm) glutathione reductase 0.0038 0.007 0.0085
Trypanosoma brucei glucosidase, putative 0.004 0.0076 0.2089
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0335 0.0407
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0018 0.0018
Echinococcus multilocularis GPCR, family 2 0.007 0.0177 0.0177
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0072 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.024 0.0728 0.0885
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0095
Echinococcus multilocularis isocitrate dehydrogenase 0.0055 0.0126 0.0126
Brugia malayi MH2 domain containing protein 0.0507 0.1598 0.1943
Echinococcus multilocularis musashi 0.0122 0.0343 0.0343
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0006 0.0006
Echinococcus granulosus Smad4 0.0035 0.006 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0076 0.0125
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0122 0.0343 0.0418
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus neuropeptide receptor A26 0.1618 0.5213 0.5213
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni alpha-glucosidase 0.0154 0.0447 0.0447
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0153 0.0153
Brugia malayi ORL1-like opioid receptor 0.0022 0.0018 0.0021
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0069 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Brugia malayi beta-lactamase family protein 0.0038 0.0072 0.0087
Echinococcus granulosus zinc finger protein 0.0023 0.0022 0.0022
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.0059 0.0059
Onchocerca volvulus 0.003 0.0046 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.3607
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0076 0.0125
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.024 0.0728 0.0885
Brugia malayi intermediate filament protein 0.0122 0.0343 0.0418
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0381 0.0381
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0086 0.0073
Brugia malayi Pre-SET motif family protein 0.0203 0.0609 0.0741
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0381 0.1666
Echinococcus multilocularis smad 0.0035 0.006 0.006
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0018 0.0018
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.004 0.0077 0.1616
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.2968
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.007 0.3284
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0018 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0076 0.1839
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.0059 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Loa Loa (eye worm) beta-lactamase 0.0038 0.0072 0.0087
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0018 0.0021
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0223 0.0672 0.0817
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0072 0.3555
Loa Loa (eye worm) isocitrate dehydrogenase 0.0055 0.0126 0.0153
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0072 0.1954
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0076 0.0076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0335 0.0711
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0101 0.0101
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6419
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0076 0.1603
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0221 0.5597
Echinococcus multilocularis cpg binding protein 0.0067 0.0165 0.0165
Plasmodium falciparum thioredoxin reductase 0.0038 0.007 0.3284
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0031 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0101 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.1854
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.006 0.006
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0018 0.0018
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.004 0.0077 0.0077
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0052 0.1193
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0335 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0022 0.0018 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0059 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0018 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0018 0.0018
Brugia malayi nuclear receptor NHR-88 0.0034 0.0059 0.0072
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.006 0.006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni intermediate filament proteins 0.0122 0.0343 0.0343
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.0519 0.1637 0.1991
Brugia malayi steroid hormone receptor 0.0034 0.0059 0.0072
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0337 0.8781
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0226 0.0836
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0022 0.0018 0.0018
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.0528 0.0642
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0069 0.0069
Onchocerca volvulus 0.0022 0.0018 0.0045
Schistosoma mansoni hypothetical protein 0.0152 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Brugia malayi Serotonin receptor 0.0022 0.0018 0.0021
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0018 0.0018
Schistosoma mansoni retinoic acid receptor RXR 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus orexin receptor type 2 0.0022 0.0018 0.0018
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0093 0.0104
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0072 0.0087
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0018 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0042 0.0759
Brugia malayi PHD-finger family protein 0.0028 0.0039 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Onchocerca volvulus Huntingtin homolog 0.0425 0.1331 0.3383
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni lamin 0.0122 0.0343 0.0343
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0018 0.0021
Onchocerca volvulus 0.0106 0.0292 0.0742
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.006 0.006
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0086 0.1875
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0018 0.0045
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0335 0.1417
Echinococcus granulosus somatostatin receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0059 0.0138 0.0138
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.0059 0.0059
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.004 0.0077 0.0077
Echinococcus multilocularis muscleblind protein 1 0.0489 0.1537 0.1537
Brugia malayi RNA binding protein 0.0063 0.0153 0.0186
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0093 0.2375
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.0059 0.0059
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0014 0.0017
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.007 0.0177 0.0177
Onchocerca volvulus 0.0022 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0093 0.2609
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0086 0.015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0093 0.2609
Schistosoma mansoni bromodomain containing protein 0.0066 0.0162 0.0162
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Loa Loa (eye worm) hypothetical protein 0.007 0.0177 0.0215
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0063 0.17
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.0059 0.0072
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0018 0.0018
Toxoplasma gondii isocitrate dehydrogenase 0.0055 0.0126 0.2968
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.007 0.0085
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0072 0.0072
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.0059 0.0059
Echinococcus multilocularis sex peptide receptor 0.0022 0.0018 0.0018
Brugia malayi Latrophilin receptor protein 2 0.007 0.0177 0.0215
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0034 0.0059 0.0059
Onchocerca volvulus 0.0038 0.0072 0.0183
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0084 0.0221 0.0221
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.0059 0.0072
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0226 0.0827
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.007 0.0177 0.0177
Giardia lamblia GTOR 0.0045 0.0093 0.0104
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.0059 0.0072
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0006 0.0006
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi 6-phosphofructokinase 0.0119 0.0335 0.0407
Echinococcus granulosus hypothetical protein 0.0022 0.0018 0.0018
Echinococcus granulosus allatostatin A receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) RNA binding protein 0.0063 0.0153 0.0186
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Trypanosoma brucei 2OG-Fe(II) oxygenase superfamily, putative 0.0022 0.0018 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0072 0.0115
Echinococcus granulosus tumor protein p63 0.0337 0.1044 0.1044
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0072 0.17
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Echinococcus multilocularis tumor protein p63 0.0337 0.1044 0.1044
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0086 0.0086
Echinococcus multilocularis FTZ F1 alpha 0.0034 0.0059 0.0059
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0221 0.0488
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0086 0.015
Loa Loa (eye worm) hypothetical protein 0.0056 0.0131 0.016
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0072 0.0012
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Loa Loa (eye worm) hypothetical protein 0.0059 0.0138 0.0168
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0018 0.0018
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.0059 0.0059
Echinococcus multilocularis geminin 0.0774 0.2465 0.2465
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.1875
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0018 0.0018
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0018 0.0021
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0018 0.0018
Brugia malayi nuclear hormone receptor 0.0034 0.0059 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi Bromodomain containing protein 0.0038 0.007 0.0086
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0018 0.0021
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0052 0.5
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0022 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.0116
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0018 0.0021
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6419
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Brugia malayi glutaminase DH11.1 0.0636 0.2016 0.2452
Brugia malayi prolyl 4-hydroxylase 0.0022 0.0018 0.0022
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0226 0.0836
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0257 0.1003
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0052 0.1193
Schistosoma mansoni hypothetical protein 0.0332 0.1029 0.1029
Onchocerca volvulus 0.0103 0.0283 0.072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.0059 0.0072
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Schistosoma mansoni histamine h1 receptor 0.0022 0.0018 0.0018
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Echinococcus granulosus fmrfamide receptor 0.0022 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0059 0.0059
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0335 0.1352
Plasmodium vivax SET domain protein, putative 0.003 0.0046 0.0477
Loa Loa (eye worm) hypothetical protein 0.0425 0.1331 0.1619
Brugia malayi Dopamine receptor 0.0022 0.0018 0.0021
Onchocerca volvulus 0.0022 0.0018 0.0045
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0335 0.0335
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2151
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0072 0.0012
Brugia malayi nuclear receptor RXR 0.0018 0.0006 0.0008
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Leishmania major hypothetical protein, conserved 0.0038 0.0072 0.1482
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.007 0.0177 0.0215
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0072 0.17
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0122 0.0343 0.0873
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0018 0.0018
Brugia malayi Muscleblind-like protein 0.0489 0.1537 0.187
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0034 0.0059 0.0059
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0086 0.0086
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.015 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Brugia malayi Isocitrate dehydrogenase 0.0055 0.0126 0.0153
Echinococcus granulosus dnaJ subfamily B 0.0469 0.1472 0.1472
Brugia malayi putative neuropeptide receptor 0.0022 0.0018 0.0021
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0609 0.0741
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0728 0.0728
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0076 0.0125
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.007 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0381 0.0381
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Onchocerca volvulus 0.0038 0.0072 0.0183
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0052 0.0937
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.0059 0.0072
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0381 1
Echinococcus multilocularis survival motor neuron protein 1 0.0519 0.1637 0.1637
Brugia malayi 6-phosphofructokinase 0.0119 0.0335 0.0407
Echinococcus multilocularis X box binding protein 1 0.0332 0.1029 0.1029
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0018 0.0021
Loa Loa (eye worm) Smad1 0.0035 0.006 0.0073
Trypanosoma brucei ubiquitin-protein ligase, putative 0.004 0.0077 0.2103
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Brugia malayi sulfakinin receptor protein 0.0022 0.0018 0.0021
Brugia malayi phosphofructokinase 0.0119 0.0335 0.0407
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0018 0.0021
Onchocerca volvulus 0.0022 0.0018 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi neuropeptide F receptor 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0076 0.1839
Brugia malayi cytoplasmic intermediate filament protein 0.0065 0.016 0.0194
Echinococcus granulosus sex peptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0152 0.0443 0.0539
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0929 0.297 0.297
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0076 0.0093
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0065 0.016 0.0194
Echinococcus granulosus lamin dm0 0.0122 0.0343 0.0343
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Echinococcus granulosus muscleblind protein 0.0489 0.1537 0.1537
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0031 0.0031
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.0059 0.015
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0106 0.0292 0.0355
Echinococcus multilocularis lamin 0.0122 0.0343 0.0343
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0101 0.0101
Schistosoma mansoni Smad4 0.0035 0.006 0.006
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0076 0.0125
Echinococcus multilocularis lamin dm0 0.0122 0.0343 0.0343
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Brugia malayi Inositol-1 0.0043 0.0086 0.0105
Onchocerca volvulus 0.0231 0.07 0.1779
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.0059 0.015
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.035 0.1087 0.1321
Mycobacterium leprae Probable lipase LipE 0.0038 0.0072 0.0001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.0018 0.0021
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0076 0.0076
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.3404
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0045 0.0048
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0072 0.0087
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0018 0.0021
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0063 0.1253
Loa Loa (eye worm) glutaminase 0.0636 0.2016 0.2452
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0018 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Brugia malayi Bromodomain containing protein 0.0078 0.02 0.0243
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0335 0.0335
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0375 0.0375
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0774 0.2465 0.2465
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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