Detailed information for compound 163549

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 446.45 | Formula: C22H26N2O8
  • H donors: 1 H acceptors: 5 LogP: 2.28 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N[C@@H]1C(=O)N2[C@@H]1C(=O)[C@@H]([C@@H]2C(=O)OCOC(=O)C(C)(C)C)C)OCc1ccccc1
  • InChi: 1S/C22H26N2O8/c1-12-15(19(27)31-11-32-20(28)22(2,3)4)24-16(17(12)25)14(18(24)26)23-21(29)30-10-13-8-6-5-7-9-13/h5-9,12,14-16H,10-11H2,1-4H3,(H,23,29)/t12-,14+,15-,16+/m1/s1
  • InChiKey: YEVDILGVADQKHN-BVUBDWEXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans dehydrogenase 0.0022 0.0022 0.0825
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0428 0.1702 0.1702
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0023 0.0023
Schistosoma mansoni sulfide quinone reductase 0.0022 0.0022 0.0022
Loa Loa (eye worm) glutathione reductase 0.0166 0.0617 0.0617
Brugia malayi Dopamine receptor 0.0022 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0068
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0082 0.0272 0.1606
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0129 0.076
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0017 0.0017
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0002 0.002
Echinococcus granulosus lamin dm0 0.0029 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0022 0.0132
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0082 0.0272 0.1486
Schistosoma mansoni hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni neuropeptide receptor 0.0022 0.0023 0.0023
Schistosoma mansoni rab6-interacting 0.0046 0.0121 0.0121
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0023 0.0023
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0089 0.0299 0.0299
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0022 0.0022 0.0132
Loa Loa (eye worm) solute carrier family 6 member 4 0.2434 1 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0017 0.0017
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0023 0.0023
Onchocerca volvulus 0.0428 0.1702 0.1702
Brugia malayi G-protein coupled receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0035 0.0075 0.0075
Echinococcus multilocularis mitogen activated protein kinase 0.0114 0.0403 0.0403
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0023 0.0023
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0022 0.0132
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0428 0.1702 0.1702
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus multilocularis glutamate synthase 0.0022 0.0022 0.0022
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0023 0.0023
Entamoeba histolytica thioredoxin reductase, putative 0.0022 0.0022 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0023 0.0023
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0114 0.0403 0.2368
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0021 0.0017 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0075 0.0075
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0428 0.1702 0.1702
Brugia malayi Pre-SET motif family protein 0.0241 0.0928 0.0928
Onchocerca volvulus 0.0022 0.0023 0.0022
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0082 0.0272 1
Toxoplasma gondii hypothetical protein 0.0428 0.1702 1
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0403 0.3681
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0022 0.0022 0.0022
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0023 0.0023
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0428 0.1702 0.1702
Loa Loa (eye worm) hypothetical protein 0.0036 0.0081 0.0081
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0022 0.0022 0.0132
Mycobacterium ulcerans DNA polymerase IV 0.0048 0.0129 0.4734
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0403 0.3681
Trichomonas vaginalis DNA polymerase eta, putative 0.0048 0.0129 0.1065
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0028 0.0049 0.0049
Schistosoma mansoni rab6-interacting 0.0046 0.0121 0.0121
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0068
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0023 0.0023
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0054 0.0054
Brugia malayi Doublecortin family protein 0.0046 0.0121 0.0121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0043 0.0108 0.0108
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0017 0.0017
Echinococcus multilocularis neuropeptide s receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi Calcitonin receptor-like protein seb-1 0.0169 0.0632 0.0632
Schistosoma mansoni amine GPCR 0.0022 0.0023 0.0023
Schistosoma mansoni amine GPCR 0.0405 0.1609 0.1609
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0022 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0017 0.0017
Trypanosoma brucei DNA polymerase IV, putative 0.0048 0.0129 0.076
Schistosoma mansoni adenoreceptor 0.0022 0.0023 0.0023
Echinococcus granulosus allatostatin A receptor 0.0022 0.0023 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0022 0.0051
Echinococcus granulosus dna polymerase eta 0.0017 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0022 0.0023 0.0023
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0428 0.1702 0.1702
Plasmodium vivax hypothetical protein, conserved 0.0428 0.1702 1
Echinococcus granulosus g protein coupled receptor 0.0022 0.0023 0.0023
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0079 0.026 0.232
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.0285 0.0285
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0022 0.0022 0.0022
Brugia malayi Cyclic-nucleotide gated cation channel 0.0021 0.0017 0.0017
Schistosoma mansoni lamin 0.0029 0.0054 0.0054
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0017 0.0017
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0053 0.0154 0.0154
Onchocerca volvulus 0.0022 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Brugia malayi G-protein coupled receptor 0.0022 0.0023 0.0023
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0089 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.0274 0.1064 0.1064
Brugia malayi follicle stimulating hormone receptor 0.0022 0.0023 0.0023
Brugia malayi neuropeptide F receptor 0.0022 0.0023 0.0023
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.007 0.007
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0428 0.1702 0.1702
Echinococcus granulosus lipoxygenase domain containing protein 0.0046 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Trypanosoma cruzi NADH dehydrogenase, putative 0.0022 0.0022 0.0132
Schistosoma mansoni netrin receptor unc5 0.0017 0.0001 0.0001
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0246 0.2183
Toxoplasma gondii hypothetical protein 0.0428 0.1702 1
Brugia malayi Pre-SET motif family protein 0.0035 0.0075 0.0075
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0021 0.0017 0.0017
Plasmodium vivax thioredoxin reductase, putative 0.0166 0.0617 0.354
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi larval opioid receptor 0.0022 0.0023 0.0023
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0169 0.0632 0.0632
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.0403 0.2379
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0428 0.1702 0.1702
Loa Loa (eye worm) hypothetical protein 0.0428 0.1702 0.1702
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0022 0.0022 0.0132
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0097 0.0574
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Plasmodium vivax amine transporter, putative 0.0428 0.1702 1
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0021 0.0017 0.0017
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0428 0.1702 0.1702
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0022
Schistosoma mansoni lamin 0.0029 0.0054 0.0054
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0082 0.0272 0.1606
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0054 0.0054
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi Thioredoxin reductase 0.0166 0.0617 0.0617
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Echinococcus granulosus glutamate synthase 0.0022 0.0022 0.0022
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0023 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0403 0.3681
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0114 0.0403 0.2379
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0023 0.0023
Schistosoma mansoni polycystin 1-related 0.0046 0.0121 0.0121
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0022 0.0022 1
Brugia malayi RE15519p 0.0022 0.0023 0.0023
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0023 0.0023
Schistosoma mansoni amine GPCR 0.0022 0.0023 0.0023
Giardia lamblia Kinase, CMGC MAPK 0.0114 0.0403 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0017 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0022 0.0022 0.0293
Loa Loa (eye worm) heterochromatin protein 1 0.0076 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0023 0.0023
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.0022 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0017 0.0017
Onchocerca volvulus 0.2434 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi Uncoordinated protein 44 0.0017 0.0001 0.0001
Brugia malayi Serotonin receptor 0.0554 0.2225 0.2225
Echinococcus granulosus RUN 0.0046 0.0121 0.0121
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0082 0.0272 0.1606
Schistosoma mansoni disulfide oxidoreductase 0.0022 0.0022 0.0022
Echinococcus granulosus serotonin receptor 0.0022 0.0023 0.0023
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0223 0.0223
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.0022 0.0051
Brugia malayi Cytochrome P450 family protein 0.0027 0.0042 0.0042
Leishmania major trypanothione reductase 0.0166 0.0617 0.3642
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0142 0.0518 0.6748
Brugia malayi neuropeptide F receptor 0.0022 0.0023 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0023 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0042 0.0247
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0163 0.0163
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Schistosoma mansoni sodium/chloride dependent transporter 0.0429 0.1707 0.1707
Mycobacterium tuberculosis Probable oxidoreductase 0.0202 0.0768 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0023 0.0023
Plasmodium falciparum amino acid transporter, putative 0.0428 0.1702 1
Schistosoma mansoni opsin-like receptor 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0142 0.0518 0.6748
Schistosoma mansoni hypothetical protein 0.0053 0.0154 0.0154
Onchocerca volvulus 0.0033 0.007 0.0069
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0042 0.0247
Echinococcus multilocularis sex peptide receptor 0.0022 0.0023 0.0023
Echinococcus granulosus dna polymerase kappa 0.0048 0.0129 0.0129
Brugia malayi glutamate synthase 0.0022 0.0022 0.0022
Echinococcus multilocularis sodium and chloride dependent glycine 0.0428 0.1702 0.1702
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0223 0.0223
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.0022 0.0022
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0042 0.0042
Brugia malayi glutathione reductase 0.0166 0.0617 0.0617
Brugia malayi hypothetical protein 0.0046 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0218 0.0833 0.0833
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0022 0.0132
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0082 0.0272 0.1486
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0082 0.0272 0.0272
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0223 0.8191
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Echinococcus multilocularis lipoxygenase domain containing protein 0.0046 0.0121 0.0121
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0428 0.1702 0.1702
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0022 0.0022 0.0293
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0428 0.1702 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.0023 0.0023
Brugia malayi polk-prov protein 0.0036 0.0081 0.0081
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0022 0.0022 0.0022
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0022 0.0022 0.0825
Onchocerca volvulus 0.0022 0.0023 0.0022
Mycobacterium ulcerans DNA polymerase IV 0.0048 0.0129 0.4734
Trichomonas vaginalis apoptosis inducing factor, putative 0.0022 0.0022 0.0051
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0082 0.0272 0.0272
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0428 0.1702 0.1702
Brugia malayi latrophilin 2 splice variant baaae 0.0116 0.041 0.041
Brugia malayi Heterochromatin protein 1 0.0076 0.0246 0.0246
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0129 0.076
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0057 0.0379
Leishmania major DNA polymerase kappa, putative 0.0024 0.0033 0.0195
Trichomonas vaginalis mercuric reductase, putative 0.0082 0.0272 0.2431
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0223 0.0223
Schistosoma mansoni loxhd1 0.0046 0.0121 0.0121
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.0127 0.0127
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0022 0.0022 0.0132
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0166 0.0617 0.8041
Onchocerca volvulus 0.0022 0.0023 0.0022
Schistosoma mansoni hypothetical protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0089 0.0299 0.0299
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0082 0.0272 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0022 0.0022 0.0825
Trypanosoma brucei DNA polymerase IV, putative 0.0048 0.0129 0.076
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0023 0.0023
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0428 0.1702 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0023 0.0023
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0114 0.0403 0.2379
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.0022 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0023 0.0023
Echinococcus granulosus lipoxygenase domain containing protein 0.0046 0.0121 0.0121
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0202 0.0768 1
Schistosoma mansoni survival motor neuron protein 0.0056 0.0163 0.0163
Echinococcus granulosus mitogen activated protein kinase 3 0.0114 0.0403 0.0403
Brugia malayi Death domain containing protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0114 0.0403 0.2379
Onchocerca volvulus 0.0022 0.0023 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0049 0.0049
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0082 0.0272 0.1606
Schistosoma mansoni amine GPCR 0.0022 0.0023 0.0023
Brugia malayi hypothetical protein 0.0046 0.0121 0.0121
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0022 0.0022 0.0022
Schistosoma mansoni sodium/chloride dependent transporter 0.0428 0.1702 0.1702
Echinococcus multilocularis serotonin receptor 0.0022 0.0023 0.0023
Echinococcus granulosus chromobox protein 1 0.0076 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0075 0.0075
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0082 0.0272 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0108 0.0869
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0003 0.0003
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0024 0.0033 0.0195
Echinococcus granulosus lamin 0.0029 0.0054 0.0054
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0022 0.0022 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0022 0.0132
Onchocerca volvulus 0.0029 0.0054 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Treponema pallidum sodium- and chloride- dependent transporter 0.2434 1 1
Plasmodium vivax SET domain protein, putative 0.0035 0.0075 0.0314
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0028 0.0049 0.0049
Brugia malayi Serotonin receptor 0.0022 0.0023 0.0023
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0122 0.0996
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0023 0.0023
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0057 0.0379
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0023 0.0023
Trypanosoma cruzi NADH dehydrogenase, putative 0.0022 0.0022 0.0132
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0428 0.1702 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0053 0.0154 0.0154
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0021 0.0017 0.0017
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0082 0.0272 0.0272
Schistosoma mansoni biogenic amine receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis chromobox protein 1 0.0076 0.0246 0.0246
Echinococcus granulosus geminin 0.0381 0.1507 0.1507
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0122 0.0996
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0428 0.1702 0.1702
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni sodium-dependent amino acid transporter 0.0428 0.1702 0.1702
Echinococcus granulosus hypothetical protein 0.0821 0.3327 0.3327
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0428 0.1702 0.1702
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0082 0.0272 0.1606
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0022 0.0022 0.0293
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0428 0.1702 0.1702
Echinococcus granulosus chromobox protein 1 0.0076 0.0246 0.0246
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0223 0.8191
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0022 0.0022 0.0022
Onchocerca volvulus 0.0022 0.0023 0.0022
Trypanosoma brucei C-8 sterol isomerase, putative 0.0426 0.1695 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0022 0.0132
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0223 0.2904
Leishmania major hypothetical protein, conserved 0.0022 0.0022 0.0132
Echinococcus multilocularis neuropeptide receptor A26 0.0022 0.0023 0.0023
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.2434 1 1
Treponema pallidum NADH oxidase 0.0082 0.0272 0.025
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0272 0.1606
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0022 0.0022 0.0293
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.0022 0.0051
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0023 0.0023
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0022 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.0096 0.0331 0.0331
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0022 0.0022 0.0022
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.0022 0.0022
Onchocerca volvulus 0.0046 0.0121 0.012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0122 0.0121
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0022 0.0022 1
Echinococcus multilocularis survival motor neuron protein 1 0.0274 0.1064 0.1064
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0082 0.0272 0.1606
Schistosoma mansoni opsin-like receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0023 0.0023
Trypanosoma brucei protein kinase, putative 0.0114 0.0403 0.2379
Mycobacterium tuberculosis Probable reductase 0.0142 0.0518 0.6748
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0428 0.1702 0.1702
Schistosoma mansoni chromobox protein 0.0076 0.0246 0.0246
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0022 0.0022 0.0132
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus multilocularis somatostatin receptor 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0082 0.0272 0.3545
Onchocerca volvulus 0.0022 0.0023 0.0022
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0022 0.0051
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) doublecortin family protein 0.0046 0.0121 0.0121
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0022 0.0022 0.0825
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0075 0.0075
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0053 0.0154 0.0154
Trichomonas vaginalis set domain proteins, putative 0.0274 0.1066 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0272 0.1606
Onchocerca volvulus 0.0022 0.0023 0.0022
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0022 0.0051
Echinococcus granulosus sex peptide receptor 0.0022 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Toxoplasma gondii thioredoxin reductase 0.0166 0.0617 0.3626
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus granulosus neuropeptide receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0023 0.0023
Schistosoma mansoni opsin-like receptor 0.0022 0.0023 0.0023
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0048 0.0129 0.1065
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0023 0.0023
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0023 0.0023
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0108 0.0869
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0054 0.0054
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Brugia malayi putative neuropeptide receptor 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0022 0.0022 0.0293
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0082 0.0272 0.1606
Brugia malayi Latrophilin receptor protein 2 0.0053 0.0154 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0428 0.1702 0.1702
Loa Loa (eye worm) hypothetical protein 0.0028 0.0049 0.0049
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0022 0.0022 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0272 0.1606
Schistosoma mansoni hypothetical protein 0.0056 0.0163 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0023 0.0023
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0428 0.1702 1
Echinococcus granulosus g protein coupled receptor 0.0022 0.0023 0.0023
Onchocerca volvulus 0.0022 0.0022 0.0021
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0023 0.0023
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0022 0.0022 0.0825
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0082 0.0272 0.0272
Schistosoma mansoni hypothetical protein 0.0116 0.041 0.041
Brugia malayi hypothetical protein 0.0428 0.1702 0.1702
Brugia malayi ORL1-like opioid receptor 0.0022 0.0023 0.0023
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0426 0.1695 0.1695
Echinococcus granulosus neuropeptide receptor 0.0022 0.0023 0.0023
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0114 0.0403 0.2379
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0381 0.1507 0.1507
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0022 0.0022 1
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0022 0.0022 0.0132
Loa Loa (eye worm) hypothetical protein 0.0169 0.0632 0.0632
Onchocerca volvulus 0.0029 0.0054 0.0053
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0023 0.0023
Brugia malayi Protein kinase domain containing protein 0.0018 0.0005 0.0005
Echinococcus granulosus Ankyrin 0.0017 0.0002 0.0002
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0022 0.0022 0.0132
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0022 0.0022 0.0132
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0082 0.0272 0.1486
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0202 0.0768 1
Echinococcus multilocularis conserved hypothetical protein 0.0799 0.3236 0.3236
Trypanosoma brucei trypanothione reductase 0.0166 0.0617 0.3642
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Onchocerca volvulus 0.0022 0.0023 0.0022
Onchocerca volvulus 0.0022 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.006 0.0182 0.0182
Echinococcus multilocularis RUN 0.0046 0.0121 0.0121
Echinococcus granulosus somatostatin receptor 0.0022 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0046 0.0121 0.0121
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0023 0.0023
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0022 0.0022 0.0132
Giardia lamblia NADH oxidase lateral transfer candidate 0.0082 0.0272 0.6557
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0082 0.0272 0.1606
Trichomonas vaginalis glutathione reductase, putative 0.0082 0.0272 0.2431
Brugia malayi hypothetical protein 0.0274 0.1064 0.1064
Brugia malayi MAP kinase sur-1 0.0114 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0017
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0202 0.0768 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0075 0.0075
Mycobacterium ulcerans ferredoxin reductase 0.0022 0.0022 0.0825
Schistosoma mansoni hypothetical protein 0.0381 0.1507 0.1507
Echinococcus granulosus g protein coupled receptor 0.0022 0.0023 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0129 0.076
Onchocerca volvulus 0.0022 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0023 0.0023
Mycobacterium ulcerans monoxygenase 0.0022 0.0022 0.0825
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0142 0.0518 0.6748
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0426 0.1695 1
Plasmodium falciparum glutathione reductase 0.0082 0.0272 0.1486
Echinococcus multilocularis voltage gated potassium channel 0.0028 0.0049 0.0049
Echinococcus granulosus orexin receptor type 2 0.0022 0.0023 0.0023
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni lipoxygenase 0.0118 0.0421 0.0421
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0023 0.0023
Brugia malayi Dopamine receptor protein 2 0.0022 0.0023 0.0023
Plasmodium vivax glutathione reductase, putative 0.0166 0.0617 0.354
Onchocerca volvulus 0.0428 0.1702 0.1702
Trypanosoma cruzi trypanothione reductase, putative 0.0082 0.0272 0.1606
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0022 0.0022 0.0825
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.02 0.0761 0.0761
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0075 0.0075
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0053 0.0154 0.0154
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0002 0.0002
Brugia malayi Cytochrome P450 family protein 0.0027 0.0042 0.0042
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0082 0.0272 0.1606
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0023 0.0023
Leishmania major hypothetical protein, conserved 0.0022 0.0022 0.0132
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0023 0.0023
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0023 0.0023
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi GnHR receptor homolog 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Mycobacterium ulcerans hypothetical protein 0.0022 0.0022 0.0825
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0089 0.0299 0.0299
Schistosoma mansoni neuropeptide receptor 0.0022 0.0023 0.0023
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0023 0.0022
Echinococcus multilocularis lamin 0.0029 0.0054 0.0054
Mycobacterium tuberculosis Probable dehydrogenase 0.0142 0.0518 0.6748
Echinococcus multilocularis mitogen activated protein kinase 3 0.0114 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Onchocerca volvulus 0.0274 0.1067 0.1066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0114 0.0403 0.2379
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0023 0.0023
Echinococcus granulosus Polycystic kidney disease protein 0.0046 0.0121 0.0121
Echinococcus multilocularis serotonin receptor 0.0022 0.0023 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0022 0.0051
Brugia malayi intermediate filament protein 0.0029 0.0054 0.0054
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.2434 1 1
Onchocerca volvulus 0.0056 0.0163 0.0162
Onchocerca volvulus 0.0022 0.0023 0.0022
Onchocerca volvulus 0.0022 0.0023 0.0022
Schistosoma mansoni glutamate synthase 0.0022 0.0022 0.0022
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0079 0.026 0.232
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0023 0.0023
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0082 0.0272 0.1598
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.0022 0.0132
Loa Loa (eye worm) hypothetical protein 0.0428 0.1702 0.1702
Entamoeba histolytica disulphide oxidoreductase, putative 0.0022 0.0022 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0428 0.1702 0.1702
Echinococcus granulosus arachidonate 5 lipoxygenase 0.02 0.0761 0.0761
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0024 0.0033 0.0431
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.0928 0.0928
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0002 0.0002
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0022 0.0022 0.0825
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Leishmania major cytochrome p450-like protein 0.0027 0.0042 0.0247
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0023 0.0023
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0022 0.0022 0.0051
Loa Loa (eye worm) serotonin transporter b 0.2434 1 1
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0246 0.2183
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0114 0.0403 0.2379
Schistosoma mansoni sulfide quinone reductase 0.0022 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0012 0.0068
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0022 0.0023 0.0023
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0022 0.0022 0.0051
Echinococcus multilocularis chromobox protein 1 0.0076 0.0246 0.0246
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0403 0.3681
Loa Loa (eye worm) thioredoxin reductase 0.0166 0.0617 0.0617
Echinococcus granulosus intermediate filament protein 0.0029 0.0054 0.0054
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0022 0.0022 0.0293
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0129 0.076
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0428 0.1702 0.1702
Loa Loa (eye worm) latrophilin receptor protein 2 0.0053 0.0154 0.0154
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0023 0.0023
Toxoplasma gondii selenide, water dikinase 0.0022 0.0022 0.0132
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0052
Echinococcus multilocularis dna polymerase eta 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0428 0.1702 0.1702
Echinococcus granulosus death domain containing protein 0.0017 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0053 0.0154 0.0154
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0082 0.0272 0.1606
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0023 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0022 0.0051
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0023 0.0023
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0428 0.1702 0.1702
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0428 0.1702 0.1702
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0022 0.0022 0.0132
Onchocerca volvulus 0.0046 0.0121 0.012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0022 0.0022 0.0825
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0403 0.0403
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0046 0.0121 0.0121
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0023 0.0023
Schistosoma mansoni glutamate synthase 0.0022 0.0022 0.0022
Echinococcus granulosus voltage gated potassium channel 0.0028 0.0049 0.0049
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0022 0.0022 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0003 0.0003
Plasmodium falciparum thioredoxin reductase 0.0166 0.0617 0.354
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0022 0.0022 0.0293
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0022 0.0022 0.0051
Echinococcus granulosus GPCR family 2 0.0053 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0053 0.0154 0.0154
Echinococcus multilocularis Polycystic kidney disease protein 0.0046 0.0121 0.0121
Leishmania major C-8 sterol isomerase-like protein 0.0426 0.1695 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0166 0.0617 0.0617
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0023 0.0023
Schistosoma mansoni neuropeptide receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0023 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0042 0.0247
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0428 0.1702 0.1702
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Brugia malayi AKH receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis lamin dm0 0.0029 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni DNA polymerase eta 0.0017 0.0002 0.0002
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0223 0.1315
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.006 0.0182 0.0182
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0023 0.0022
Brugia malayi sulfakinin receptor protein 0.0022 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0023 0.0023
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0223 0.1309
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0023 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0023 0.0023
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0022 0.0022 1
Onchocerca volvulus 0.0428 0.1702 0.1702
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0053 0.0154 0.0154
Trypanosoma brucei unspecified product 0.004 0.0097 0.0574
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0023 0.0023
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0053 0.0154 0.0154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0272 0.1606
Schistosoma mansoni amine GPCR 0.0022 0.0023 0.0023
Plasmodium falciparum glutathione reductase 0.0166 0.0617 0.354
Echinococcus multilocularis musashi 0.0029 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0428 0.1702 0.1702
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis serotonin transporter 0.2434 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0023 0.0023
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0017 0.0017
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0428 0.1702 0.1702
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0023 0.0023
Brugia malayi Dopamine receptor protein 1 0.0022 0.0023 0.0023
Trypanosoma cruzi trypanothione reductase, putative 0.0166 0.0617 0.3642
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0023 0.0023
Plasmodium falciparum thioredoxin reductase 0.0082 0.0272 0.1486
Echinococcus granulosus serotonin transporter 0.2434 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Brugia malayi Cytochrome P450 family protein 0.0061 0.0183 0.0183
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0023 0.0023
Plasmodium falciparum LCCL domain-containing protein 0.0046 0.0121 0.0587
Schistosoma mansoni intermediate filament proteins 0.0029 0.0054 0.0054
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0022 0.0022 0.0022
Echinococcus multilocularis thioredoxin glutathione reductase 0.0166 0.0617 0.0617
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0023 0.0023
Schistosoma mansoni histamine h1 receptor 0.0022 0.0023 0.0023
Trichomonas vaginalis glutamate synthase, putative 0.0022 0.0022 0.0051
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0001 0.0001
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0028 0.0049 0.0049
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0022 0.0022 0.0293
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0017 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0272 0.1606
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0042 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0081 0.0478
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0022 0.0022 0.0022
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0017 0.0017
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Mycobacterium ulcerans glutamate synthase subunit beta 0.0022 0.0022 0.0825
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0002 0.0002
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0033 0.0195
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0023 0.0023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0082 0.0272 0.1606
Loa Loa (eye worm) hypothetical protein 0.2434 1 1
Echinococcus multilocularis geminin 0.0381 0.1507 0.1507
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0002 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.0096 0.0331 0.0331
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0169 0.0632 0.0632
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0022 0.0022 0.0051
Brugia malayi G protein-coupled receptor 0.0022 0.0023 0.0023
Echinococcus granulosus sodium and chloride dependent glycine 0.0428 0.1702 0.1702
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0081 0.0478
Loa Loa (eye worm) programmed cell death 8 0.0022 0.0022 0.0022
Mycobacterium ulcerans NADH dehydrogenase 0.0022 0.0022 0.0825
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0042 0.1541
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0023 0.0023
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0082 0.0272 1
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.2434 1 1
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0023 0.0023
Schistosoma mansoni sodium/chloride dependent transporter 0.2434 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0023 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0022 0.0132
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0002 0.0002
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0223 0.8191
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.0285 0.0285
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0023 0.0023
Giardia lamblia DINP protein human, muc B family 0.0024 0.0033 0.028
Toxoplasma gondii NADPH-glutathione reductase 0.0082 0.0272 0.1598
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0428 0.1702 0.1702
Loa Loa (eye worm) hypothetical protein 0.0116 0.041 0.041
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0075 0.0075
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0017 0.0017
Loa Loa (eye worm) norepinephrine transporter 0.2434 1 1
Brugia malayi hypothetical protein 0.0022 0.0023 0.0023
Echinococcus granulosus survival motor neuron protein 1 0.0274 0.1064 0.1064
Onchocerca volvulus 0.0022 0.0023 0.0022
Brugia malayi Melatonin receptor type 1A 0.0022 0.0023 0.0023
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0017 0.0017
Schistosoma mansoni lipoxygenase 0.02 0.0761 0.0761
Brugia malayi chromobox protein homolog 3 0.0043 0.0108 0.0108
Trypanosoma brucei NADH dehydrogenase 0.0022 0.0022 0.0132
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0002 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0075 0.0441
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0023 0.0023
Echinococcus granulosus sodium and chloride dependent glycine 0.0428 0.1702 0.1702
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0082 0.0272 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Echinococcus multilocularis lipoxygenase domain containing protein 0.0046 0.0121 0.0121
Trypanosoma brucei hypothetical protein, conserved 0.0022 0.0022 0.0132
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0023 0.0023
Echinococcus multilocularis dna polymerase kappa 0.0048 0.0129 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0022 0.0022 0.0293
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0077 0.0252 0.0252
Echinococcus multilocularis GPCR, family 2 0.0053 0.0154 0.0154
Onchocerca volvulus 0.0047 0.0127 0.0125
Leishmania major NADH dehydrogenase, putative 0.0022 0.0022 0.0132
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0023 0.0023
Leishmania major DNA polymerase eta, putative 0.0017 0.0002 0.0009
Plasmodium vivax multidomain scavenger receptor, putative 0.0046 0.0121 0.0587
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Echinococcus multilocularis sodium and chloride dependent glycine 0.0428 0.1702 0.1702
Schistosoma mansoni neuropeptide receptor 0.0022 0.0023 0.0023
Echinococcus granulosus neuropeptide receptor A26 0.0022 0.0023 0.0023
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0426 0.1695 0.1695
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0001 0.0001
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Schistosoma mansoni myosin xvIII 0.0022 0.0023 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0023 0.0023
Onchocerca volvulus 0.0022 0.0023 0.0022
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0023 0.0023
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0082 0.0272 0.1486
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Onchocerca volvulus 0.0022 0.0023 0.0022
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0428 0.1702 0.1702
Plasmodium falciparum transporter, putative 0.0428 0.1702 1
Onchocerca volvulus 0.0022 0.0023 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0129 0.076
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0022 0.0022 0.0022
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0023 0.0023
Echinococcus granulosus fmrfamide receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0023
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1934 0.7933 0.7933
Echinococcus granulosus neuropeptide s receptor 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0142 0.0518 0.6748
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0082 0.0272 0.1486
Schistosoma mansoni glutamate synthase 0.0022 0.0022 0.0022
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0023 0.0023
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0022 0.0022 0.0022
Echinococcus granulosus mitogen activated protein kinase 0.0114 0.0403 0.0403
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0022 0.0022 0.0022
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0046 0.0121 0.0121
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0114 0.0403 0.0403
Schistosoma mansoni chromobox protein 0.0076 0.0246 0.0246
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0142 0.0518 0.6748
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0022 0.0022 0.0293
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0053 0.0154 0.0154
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.007 0.007
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0108 0.0107
Echinococcus multilocularis Ankyrin 0.0017 0.0002 0.0002

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 100 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in S. aureus 005 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in S. aureus 400 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in E. coli 266 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in E. coli 129 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration in brain-heart infusion broth in presence of hog liver esterase(1:1.5) in K. pneumoniae 079 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in M. morganii 001 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in Serr. marc. 095 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in Citrobacter diversus 031 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in Enterococcus cloacae 009 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in Pseudomonas aeruginosa 104 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in E. coli 266 ChEMBL. 2404120
MIC (functional) > 200 ug ml-1 In vitro minimal inhibitory concentration (MIC) in brain-heart infusion broth in the presence of hog liver esterase(1:1.5) in E. coli 129 ChEMBL. 2404120

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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