Detailed information for compound 1678828

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.264 | Formula: C17H22BrNO5
  • H donors: 2 H acceptors: 3 LogP: 1.81 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H](c1ccccc1)C(=O)O[C@@H]1C[C@@H]2[C@@H]3[C@H]([C@@H](C1)[N+]2([O-])C)O3.Br
  • InChi: 1S/C17H21NO5.BrH/c1-18(21)13-7-11(8-14(18)16-15(13)23-16)22-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14-,15-,16+,18?;/m1./s1
  • InChiKey: MGNNYKWRWHQLCR-YEGFOMENSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi MH2 domain containing protein 0.0035 0.006 0.0073
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1254 0.4028 1
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0093 0.2071
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0063 0.1437
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0018 0.0021
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0072 0.0072
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0086 0.0086
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0052 0.0937
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Brugia malayi MH2 domain containing protein 0.0507 0.1598 0.1943
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0221 0.0221
Brugia malayi Dopamine receptor 0.0022 0.0018 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Trypanosoma brucei trypanothione reductase 0.0038 0.007 0.1885
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Brugia malayi RNA binding protein 0.0063 0.0153 0.0186
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0052 0.1193
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis lamin dm0 0.0122 0.0343 0.0343
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.0059 0.015
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0084 0.0221 0.0426
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0063 0.17
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.0059 0.0059
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0093 0.0093
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni microtubule-associated protein tau 0.3089 1 1
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0086 0.0086
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0093 0.2375
Loa Loa (eye worm) transcription factor SMAD2 0.0507 0.1598 0.1943
Giardia lamblia Fructose-bisphosphate aldolase 0.1254 0.4028 1
Brugia malayi larval opioid receptor 0.0022 0.0018 0.0021
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0381 0.0381
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Echinococcus granulosus neuropeptide s receptor 0.1618 0.5213 0.5213
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0018 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.007 0.1628
Echinococcus granulosus FTZ F1 alpha 0.0034 0.0059 0.0059
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0069 0.0069
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0034 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Plasmodium vivax glutathione reductase, putative 0.0038 0.007 0.3284
Loa Loa (eye worm) hypothetical protein 0.0425 0.1331 0.1619
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0034 0.0059 0.0059
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.0059 0.0059
Schistosoma mansoni intermediate filament proteins 0.0122 0.0343 0.0343
Mycobacterium tuberculosis Probable reductase 0.0086 0.0226 0.0836
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.007 0.0177 0.0177
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0257 0.1003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0072 0.0012
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0093 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.0059 0.0072
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6419
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0034 0.0059 0.0059
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.0519 0.1637 0.1991
Loa Loa (eye worm) Smad1 0.0035 0.006 0.0073
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0076 0.0061
Brugia malayi ecdysteroid receptor 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0046 0.0046
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.0116
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0004 0.0005
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0018 0.0018
Brugia malayi sulfakinin receptor protein 0.0022 0.0018 0.0021
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.007 0.0177 0.0177
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi Dopamine receptor protein 2 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0042 0.0662
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0059 0.0072
Brugia malayi beta-lactamase family protein 0.0038 0.0072 0.0087
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0072 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0122 0.0343 0.0873
Plasmodium vivax SET domain protein, putative 0.003 0.0046 0.0477
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.006 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.0059 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus sex peptide receptor 0.0022 0.0018 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0042 0.0759
Brugia malayi G-protein coupled receptor 0.0022 0.0018 0.0021
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0076 0.0093
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.3404
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0018 0.0018
Toxoplasma gondii ABC1 family protein 0.0038 0.0072 0.1482
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0226 0.0827
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0018 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Loa Loa (eye worm) hypothetical protein 0.0519 0.1637 0.1991
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0013 0.0013
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0018 0.0018
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6419
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0076 0.0125
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Brugia malayi Pre-SET motif family protein 0.0203 0.0609 0.0741
Onchocerca volvulus 0.0022 0.0018 0.0045
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0072 0.3555
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.004 0.0077 0.0077
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni alpha glucosidase 0.004 0.0076 0.0076
Loa Loa (eye worm) glutaminase 2 0.0636 0.2016 0.2452
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0059 0.0059
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0012
Toxoplasma gondii thioredoxin reductase 0.0038 0.007 0.142
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0223 0.0672 0.0817
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0012
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0056 0.1042
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0031 0.0031
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni retinoic acid receptor RXR 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0072 0.0087
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.0018 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0335 0.8719
Echinococcus granulosus geminin 0.0774 0.2465 0.2465
Echinococcus granulosus neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.003 0.0046 0.0117
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Leishmania major hypothetical protein, conserved 0.0038 0.0072 0.1482
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis zinc finger protein 0.0023 0.0022 0.0022
Leishmania major hypothetical protein, conserved 0.0029 0.0042 0.0662
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Onchocerca volvulus 0.0038 0.0072 0.0183
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0335 0.1352
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.004 0.0077 0.1616
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Echinococcus granulosus biogenic amine 5HT receptor 0.0157 0.0458 0.0458
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0101 0.0101
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0018 0.0021
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0002
Echinococcus multilocularis musashi 0.0122 0.0343 0.0343
Onchocerca volvulus 0.0034 0.0059 0.015
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0076 0.1603
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Echinococcus granulosus neuropeptide receptor A26 0.1618 0.5213 0.5213
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0018 0.0021
Echinococcus multilocularis serotonin receptor 0.0157 0.0458 0.0458
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.2543 0.8222 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0507 0.1598 0.1943
Brugia malayi PHD-finger family protein 0.0028 0.0039 0.0047
Brugia malayi AKH receptor 0.0022 0.0018 0.0021
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0093 0.0104
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0018 0.0018
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0122 0.0343 0.0873
Echinococcus granulosus Smad4 0.0035 0.006 0.006
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0049 0.0108 0.0274
Echinococcus multilocularis Smad4 0.0035 0.006 0.006
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0221 0.0221
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Echinococcus granulosus fmrfamide receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.015 0.015
Brugia malayi Serotonin receptor 0.0022 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.0059 0.0072
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0335 0.0407
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0018 0.0018
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Echinococcus granulosus smad 0.0035 0.006 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6529
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0018 0.0018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.015 0.015
Brugia malayi Muscleblind-like protein 0.0489 0.1537 0.187
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0106 0.0292 0.0292
Loa Loa (eye worm) histone methyltransferase 0.002 0.0013 0.0015
Schistosoma mansoni alpha-glucosidase 0.0154 0.0447 0.0447
Onchocerca volvulus Huntingtin homolog 0.0425 0.1331 0.3383
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Schistosoma mansoni inositol monophosphatase 0.0043 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0157 0.0458 0.0557
Echinococcus granulosus neuropeptide receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Loa Loa (eye worm) hypothetical protein 0.0489 0.1537 0.187
Brugia malayi cytoplasmic intermediate filament protein 0.0065 0.016 0.0194
Loa Loa (eye worm) isocitrate dehydrogenase 0.0055 0.0126 0.0153
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0076 0.0076
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0929 0.297 0.297
Echinococcus granulosus tumor protein p63 0.0337 0.1044 0.1044
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0076 0.0125
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0093 0.0113
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.1854
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Echinococcus granulosus orexin receptor type 2 0.0022 0.0018 0.0018
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0084 0.0221 0.0426
Echinococcus granulosus zinc finger protein 0.0023 0.0022 0.0022
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0728 0.0728
Brugia malayi beta-lactamase family protein 0.0038 0.0072 0.0087
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Onchocerca volvulus 0.0038 0.0072 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0059 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.0059 0.0072
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0018 0.0021
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0076 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0059 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Leishmania major trypanothione reductase 0.0038 0.007 0.142
Brugia malayi Isocitrate dehydrogenase 0.0055 0.0126 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0221 0.0488
Loa Loa (eye worm) hypothetical protein 0.0056 0.0131 0.016
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0022 0.0018 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0375 0.0375
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0076 0.0076
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0022 0.0018 0.0018
Onchocerca volvulus Huntingtin homolog 0.0425 0.1331 0.3383
Brugia malayi Smad1 0.0035 0.006 0.0073
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0086 0.015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi nuclear hormone receptor 0.0034 0.0059 0.0072
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0335 0.1417
Loa Loa (eye worm) beta-lactamase 0.0038 0.0072 0.0087
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0018 0.0018
Brugia malayi CXXC zinc finger family protein 0.0061 0.0147 0.0179
Echinococcus multilocularis serotonin receptor 0.0157 0.0458 0.0458
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0093 0.0093
Brugia malayi MH2 domain containing protein 0.0035 0.006 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) glutathione reductase 0.0038 0.007 0.0085
Trichomonas vaginalis set domain proteins, putative 0.0231 0.07 0.1684
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.0059 0.0059
Giardia lamblia GTOR 0.0045 0.0093 0.0104
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0046 0.0772
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0072 0.17
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Echinococcus granulosus cpg binding protein 0.0067 0.0165 0.0165
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0069 0.0069
Schistosoma mansoni cpg binding protein 0.0061 0.0147 0.0147
Onchocerca volvulus 0.0038 0.0072 0.0183
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Brugia malayi TAR-binding protein 0.0063 0.0153 0.0186
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0101 0.0101
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0084 0.0221 0.0269
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0728 0.0728
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0059 0.0138 0.0138
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0018 0.0018
Echinococcus granulosus somatostatin receptor 0.0022 0.0018 0.0018
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.0528 0.0642
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Mycobacterium ulcerans glutaminase 0.0636 0.2016 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0014 0.0017
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0093 0.2609
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0055 0.0126 0.0301
Loa Loa (eye worm) nuclear factor I 0.0019 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0179 0.053 0.0645
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Brugia malayi Bromodomain containing protein 0.0038 0.007 0.0086
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0072 0.0072
Echinococcus granulosus dnaJ subfamily B 0.0469 0.1472 0.1472
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0072 0.0012
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0016 0.0257
Brugia malayi Serotonin receptor 0.0022 0.0018 0.0021
Echinococcus multilocularis somatostatin receptor 0.0022 0.0018 0.0018
Trypanosoma brucei ubiquitin-protein ligase, putative 0.004 0.0077 0.2103
Toxoplasma gondii isocitrate dehydrogenase 0.0055 0.0126 0.2968
Schistosoma mansoni zinc finger protein 0.0023 0.0022 0.0022
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0065 0.016 0.0194
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.024 0.0728 0.0885
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.053 0.1348
Echinococcus granulosus ubiquitin specific protease 41 0.0084 0.0221 0.0221
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0335 0.1408
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0006 0.0006
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0613 0.1941 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0063 0.1253
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.0059 0.0059
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0147 0.0179
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0072 0.0001
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.0059 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.0059 0.0072
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0153 0.0186
Loa Loa (eye worm) intermediate filament protein 0.0122 0.0343 0.0418
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0728 0.0728
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0231 0.07 0.1779
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0022
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0059 0.0059
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis microtubule associated protein 2 0.3089 1 1
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0093 0.0113
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi glutaminase DH11.1 0.0636 0.2016 0.2452
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0153 0.0153
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0084 0.0221 0.0269
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.004 0.0077 0.4137
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.0059 0.0072
Brugia malayi hypothetical protein 0.0029 0.0042 0.0051
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0072 0.0012
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Schistosoma mansoni smad 0.0035 0.006 0.006
Echinococcus multilocularis GPCR, family 2 0.007 0.0177 0.0177
Schistosoma mansoni Smad4 0.0035 0.006 0.006
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0335 0.0711
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0018 0.0018
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Loa Loa (eye worm) hypothetical protein 0.0056 0.0131 0.016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0051
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0002 0.0002
Brugia malayi G-protein coupled receptor 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0022
Echinococcus granulosus X box binding protein 1 0.0332 0.1029 0.1029
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0042 0.0759
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0018 0.0021
Schistosoma mansoni coup transcription factor 0.0034 0.0059 0.0059
Echinococcus multilocularis FTZ F1 alpha 0.0034 0.0059 0.0059
Brugia malayi Melatonin receptor type 1A 0.0022 0.0018 0.0021
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.1875
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0613 0.1941 0.9614
Loa Loa (eye worm) glutaminase 0.0636 0.2016 0.2452
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.0059 0.0072
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Brugia malayi RE15519p 0.0022 0.0018 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0153 0.0186
Loa Loa (eye worm) hypothetical protein 0.0425 0.1331 0.1619
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0055 0.0126 0.3607
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0226 0.0836
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0095
Brugia malayi glutathione reductase 0.0038 0.007 0.0085
Echinococcus granulosus GPCR family 2 0.007 0.0177 0.0177
Onchocerca volvulus 0.0103 0.0283 0.072
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0076 0.0061
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0018 0.0018
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.007 0.0177 0.0215
Brugia malayi isocitrate dehydrogenase 0.0055 0.0126 0.0153
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0018 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0006 0.0006
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0609 0.0741
Schistosoma mansoni hypothetical protein 0.0774 0.2465 0.2465
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.2968
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0086 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis sex peptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis tumor protein p63 0.0337 0.1044 0.1044
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0052 0.5
Onchocerca volvulus 0.0106 0.0292 0.0742
Schistosoma mansoni survival motor neuron protein 0.0106 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0119 0.0336 0.0409
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0335 0.0407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0019
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0101 0.0101
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0084 0.0221 0.0221
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Brugia malayi follicle stimulating hormone receptor 0.0022 0.0018 0.0021
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0226 0.0836
Schistosoma mansoni glutaminase 0.0636 0.2016 0.2016
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0002 0.0002
Schistosoma mansoni lamin 0.0122 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.0059 0.0072
Echinococcus multilocularis muscleblind protein 0.0489 0.1537 0.1537
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0086 0.0073
Loa Loa (eye worm) inositol-1 0.0043 0.0086 0.0105
Brugia malayi nuclear receptor RXR 0.0018 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Plasmodium falciparum thioredoxin reductase 0.0038 0.007 0.3284
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Brugia malayi hypothetical protein 0.0425 0.1331 0.1619
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0045 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus serotonin receptor 0.0022 0.0018 0.0018
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0335 0.0335
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0072 0.0012
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.0059 0.0072
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.006 0.006
Brugia malayi phosphofructokinase 0.0119 0.0335 0.0407
Loa Loa (eye worm) RNA binding protein 0.0063 0.0153 0.0186
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.035 0.1087 0.1321
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Loa Loa (eye worm) hypothetical protein 0.035 0.1087 0.1321
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0335 0.0335
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0072 0.17
Echinococcus granulosus hypothetical protein 0.0022 0.0018 0.0018
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0018 0.0018
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0018 0.0018
Loa Loa (eye worm) latrophilin receptor protein 2 0.007 0.0177 0.0215
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.0059 0.015
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0047 0.0101 0.0123
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0012
Schistosoma mansoni myosin xvIII 0.0022 0.0018 0.0018
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.007 0.0177 0.0177
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.0059 0.0072
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0226 0.0836
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0084 0.0221 0.0221
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.0059 0.0072
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0018 0.0018
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0018 0.0018
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0071 0.0071
Brugia malayi G protein-coupled receptor 0.0022 0.0018 0.0021
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0059 0.0072
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0052 0.0937
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0059 0.0059
Onchocerca volvulus 0.0022 0.0018 0.0046
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Schistosoma mansoni hypothetical protein 0.0774 0.2465 0.2465
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0086 0.0086
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0018 0.0018
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0061 0.0147 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Loa Loa (eye worm) hypothetical protein 0.0122 0.0343 0.0418
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0086 0.1875
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0013 0.0013
Brugia malayi MH1 domain containing protein 0.0035 0.006 0.0073
Brugia malayi Inositol-1 0.0043 0.0086 0.0105
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0059 0.0138 0.0138
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0221 0.0488
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.004 0.0077 0.4137
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.0127
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0018 0.0045
Brugia malayi MH1 domain containing protein 0.0035 0.006 0.0073
Echinococcus granulosus lamin dm0 0.0122 0.0343 0.0343
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0022 0.0018 0.0018
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0122 0.0343 0.0418
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0019
Echinococcus granulosus muscleblind protein 0.0489 0.1537 0.1537
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0072 0.0012
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0108 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0072 0.0115
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0106 0.0292 0.0355
Brugia malayi intermediate filament protein 0.0122 0.0343 0.0418
Loa Loa (eye worm) hypothetical protein 0.0152 0.0443 0.0539
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.0059 0.0072
Schistosoma mansoni histamine h1 receptor 0.0022 0.0018 0.0018
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Schistosoma mansoni bromodomain containing protein 0.0066 0.0162 0.0162
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0076 0.1839
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0018 0.0018
Echinococcus multilocularis cpg binding protein 0.0067 0.0165 0.0165
Echinococcus granulosus allatostatin A receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Trichomonas vaginalis glutaminase, putative 0.0636 0.2016 0.4972
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.024 0.0728 0.0885
Echinococcus multilocularis geminin 0.0774 0.2465 0.2465
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0335 0.0407
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0221 0.0221
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0381 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0018 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0072 0.1954
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0055 0.0126 0.0126
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.0059 0.0072
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0052 0.1193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0072 0.0072
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0055 0.0126 0.3404
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0076 0.0125
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni hypothetical protein 0.0152 0.0443 0.0443
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0728 0.0728
Schistosoma mansoni inositol monophosphatase 0.0043 0.0086 0.0086
Onchocerca volvulus 0.035 0.1087 0.2761
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.0059 0.0059
Onchocerca volvulus 0.0022 0.0018 0.0045
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0052 0.0065
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0052 0.1193
Brugia malayi N-terminal motif family protein 0.0179 0.053 0.0645
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0381 0.1666
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Trichomonas vaginalis esterase, putative 0.0038 0.0072 0.0114
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0018 0.0022
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.004 0.0077 0.0062
Brugia malayi Latrophilin receptor protein 2 0.007 0.0177 0.0215
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0153 0.0186
Brugia malayi hypothetical protein 0.0037 0.0069 0.0084
Schistosoma mansoni hypothetical protein 0.0469 0.1472 0.1472
Toxoplasma gondii isocitrate dehydrogenase 0.0055 0.0126 0.2968
Loa Loa (eye worm) hypothetical protein 0.0223 0.0672 0.0817
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0018 0.0021
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0335 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Onchocerca volvulus 0.0022 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0018 0.0018
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0018 0.0018
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0335 1
Brugia malayi GnHR receptor homolog 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni hypothetical protein 0.0332 0.1029 0.1029
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0613 0.1941 1
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0335 0.0335
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0063 0.0063
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0076 0.0093
Brugia malayi Dopamine receptor protein 1 0.0022 0.0018 0.0021
Brugia malayi Pre-SET motif family protein 0.003 0.0046 0.0056
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.007 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Echinococcus multilocularis thyroid hormone receptor alpha 0.0034 0.0059 0.0059
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.0059 0.015
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0381 0.0381
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0072 0.0012
Echinococcus multilocularis neuropeptide s receptor 0.1618 0.5213 0.5213
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0031 0.0031
Brugia malayi neuropeptide F receptor 0.0022 0.0018 0.0021
Schistosoma mansoni hypothetical protein 0.0037 0.0069 0.0069
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.2543 0.8222 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus tar DNA binding protein 0.0063 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0157 0.0458 0.0557
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0052 0.0937
Echinococcus multilocularis lamin 0.0122 0.0343 0.0343
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.006 0.0073
Brugia malayi hypothetical protein 0.0018 0.0006 0.0008
Echinococcus granulosus intermediate filament protein 0.0122 0.0343 0.0343
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.0018 0.0021
Brugia malayi 6-phosphofructokinase 0.0119 0.0335 0.0407
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.3607
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0018 0.0021
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.0059 0.0059
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0071 0.0071
Brugia malayi Calcitonin receptor-like protein seb-1 0.0223 0.0672 0.0817
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0072 0.0012
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.004 0.0077 0.1616
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0072 0.0114
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0055 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi beta-lactamase 0.0038 0.0072 0.0087
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.0059 0.0059
Brugia malayi ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0072 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0381 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2391
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0223 0.0672 0.0817
Brugia malayi latrophilin 2 splice variant baaae 0.0152 0.0443 0.0539
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0063 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Treponema pallidum fructose-bisphosphate aldolase 0.1254 0.4028 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0046 0.0046
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0055 0.0126 1
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.0742 0.3596
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0226 0.0836
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.006 0.006
Plasmodium falciparum glutathione reductase 0.0038 0.007 0.3284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Echinococcus multilocularis neuropeptide receptor A26 0.1618 0.5213 0.5213
Mycobacterium leprae Probable lipase LipE 0.0038 0.0072 0.0001
Brugia malayi prolyl 4-hydroxylase 0.0022 0.0018 0.0022
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.0059 0.0059
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0257 0.1003
Echinococcus multilocularis ubiquitin specific protease 41 0.0084 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine (5HT) receptor 0.0157 0.0458 0.0458
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.007 0.3284
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0221 0.5597
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0018 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Onchocerca volvulus 0.0022 0.0018 0.0045
Loa Loa (eye worm) hypothetical protein 0.0489 0.1537 0.187
Loa Loa (eye worm) hypothetical protein 0.0038 0.0071 0.0086
Brugia malayi Bromodomain containing protein 0.0078 0.02 0.0243
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0018 0.0018
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0076 0.1603
Echinococcus multilocularis X box binding protein 1 0.0332 0.1029 0.1029
Echinococcus multilocularis survival motor neuron protein 1 0.0519 0.1637 0.1637
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0055 0.0126 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2151
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0226 0.0836
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0072 0.0011
Trypanosoma brucei 2OG-Fe(II) oxygenase superfamily, putative 0.0022 0.0018 0.0307
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0086 0.015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.1854
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0381 0.0381
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0052 0.1193
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.0019 0.0008 0.001
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0022 0.0018 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0257 0.1003
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.1225 0.3935 1
Echinococcus multilocularis smad 0.0035 0.006 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2151
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Brugia malayi ORL1-like opioid receptor 0.0022 0.0018 0.0021
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0335 0.0335
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Brugia malayi putative neuropeptide receptor 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0059 0.0138 0.0168
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0042 0.1043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis dnaJ subfamily B 0.0469 0.1472 0.1472
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0059 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Brugia malayi Intermediate filament tail domain containing protein 0.0122 0.0343 0.0418
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0093 0.2071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis isocitrate dehydrogenase 0.0055 0.0126 0.0126
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0072 0.0072
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi nuclear receptor NHR-88 0.0034 0.0059 0.0072
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Brugia malayi steroid hormone receptor 0.0034 0.0059 0.0072
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.002 0.0014 0.0014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.007 0.0177 0.0215
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0018 0.0018
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0018 0.0018
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0093 0.0093
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0086 0.5
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi neuropeptide F receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Schistosoma mansoni cpg binding protein 0.0067 0.0165 0.0165
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.007 0.0177 0.0177
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0076 0.1839
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0018 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.0059 0.0072
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Echinococcus multilocularis muscleblind protein 1 0.0489 0.1537 0.1537
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.004 0.0077 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.0059 0.0072
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0093 0.2375
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Schistosoma mansoni adenoreceptor 0.0022 0.0018 0.0018
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.006 0.006
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.004 0.0077 0.0077
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0052 0.5
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0002
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0031 0.0031
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0101 0.0101
Trypanosoma brucei glucosidase, putative 0.004 0.0076 0.2089
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1254 0.4028 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0049 0.0108 0.0131
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.0127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0221 0.0488
Schistosoma mansoni cpg binding protein 0.0067 0.0165 0.0165
Brugia malayi Thioredoxin reductase 0.0038 0.007 0.0085
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0018 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0337 0.8781
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.0528 0.0642
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0018 0.0021
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.006 0.006
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0018 0.0018
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0018 0.0021
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0069 0.0069
Schistosoma mansoni alpha-glucosidase 0.0154 0.0447 0.0447
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.0059 0.0059
Echinococcus granulosus survival motor neuron protein 1 0.0519 0.1637 0.1637
Echinococcus granulosus lamin 0.0122 0.0343 0.0343
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0257 0.0993
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0059 0.0059
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0018 0.0018
Schistosoma mansoni lamin 0.0122 0.0343 0.0343
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.006 0.006
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0018 0.0018
Brugia malayi 6-phosphofructokinase 0.0119 0.0335 0.0407
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.0059 0.0072
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0018 0.0018
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0093 0.2609

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = -6.51 % Inhibition of electric eel AChE at 2 mg/ml by Ellman's method ChEMBL. 23062825
Inhibition (binding) = -1.85 % Inhibition of horse BChE at 2 mg/ml by Ellman's method ChEMBL. 23062825

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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