Detailed information for compound 1722606

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 450.611 | Formula: C27H31FN2OS
  • H donors: 1 H acceptors: 1 LogP: 7.03 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1cccc(c1)N(C(c1ccccc1C)C(=O)NC1CCCCC1)CCc1cccs1
  • InChi: 1S/C27H31FN2OS/c1-20-9-5-6-15-25(20)26(27(31)29-22-11-3-2-4-12-22)30(17-16-24-14-8-18-32-24)23-13-7-10-21(28)19-23/h5-10,13-15,18-19,22,26H,2-4,11-12,16-17H2,1H3,(H,29,31)
  • InChiKey: UOJAOZUTLWAVAT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi CXXC zinc finger family protein 0.0025 0.0261 0.0663
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0017 0.0157 0.0827
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Leishmania major trypanothione reductase 0.0041 0.0466 0.3463
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0017 0.0065
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0117 0.0298
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.1713 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0176 0.07
Echinococcus granulosus dna polymerase kappa 0.0019 0.0182 0.0407
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.3568 1
Trypanosoma brucei hypothetical protein 0.0109 0.133 1
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0009 0.006 0.0392
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0266 0.1946
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0094 0.1137 0.6512
Echinococcus multilocularis dnaJ subfamily B 0.0356 0.4471 0.4471
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0041 0.0041
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0124 0.0277
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Schistosoma mansoni smad1 5 8 and 0.0008 0.0043 0.0097
Schistosoma mansoni hypothetical protein 0.004 0.0448 0.1001
Loa Loa (eye worm) histone methyltransferase 0.0008 0.0041 0.0104
Loa Loa (eye worm) hypothetical protein 0.0146 0.1795 0.4567
Brugia malayi protein C24B5.3 0.0006 0.0017 0.0042
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0176 0.0937
Loa Loa (eye worm) hypothetical protein 0.0014 0.0117 0.0298
Loa Loa (eye worm) hypothetical protein 0.005 0.0584 0.1487
Brugia malayi latrophilin 2 splice variant baaae 0.003 0.032 0.0814
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0094 0.1137 0.6512
Brugia malayi Protein kinase domain containing protein 0.0087 0.1049 0.267
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.3568 1
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.3568 1
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0087 0.1049 0.7875
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Trypanosoma brucei unspecified product 0.0013 0.0108 0.0752
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0043 0.0097
Toxoplasma gondii thioredoxin reductase 0.0041 0.0466 0.7948
Onchocerca volvulus Huntingtin homolog 0.0119 0.1462 1
Loa Loa (eye worm) RNA binding protein 0.0062 0.0728 0.1852
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0266 0.562
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0014 0.0124 0.0631
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0124 0.2528
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Onchocerca volvulus Huntingtin homolog 0.0119 0.1462 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Trypanosoma brucei trypanothione reductase 0.0041 0.0466 0.3463
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0005 0.0008 0.0018
Schistosoma mansoni cpg binding protein 0.0026 0.0279 0.0623
Toxoplasma gondii histone lysine methyltransferase SET1 0.005 0.0584 1
Toxoplasma gondii patched family protein 0.0006 0.0017 0.0146
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0009 0.006 0.0255
Schistosoma mansoni DNA polymerase eta 0.0019 0.0182 0.0407
Schistosoma mansoni transcription factor LCR-F1 0.0031 0.0341 0.0762
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0176 0.0471
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0109 0.133 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0037 0.0414 0.1141
Schistosoma mansoni hypothetical protein 0.0014 0.0117 0.0262
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.1164 0.296
Loa Loa (eye worm) hypothetical protein 0.0119 0.1462 0.3719
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.3568 1
Brugia malayi hypothetical protein 0.0006 0.0017 0.0042
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0176 0.0447
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0109 0.133 1
Echinococcus multilocularis geminin 0.0165 0.2044 0.2044
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0728 0.1629
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0043
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0176 0.0151
Echinococcus multilocularis GPCR, family 2 0.0014 0.0117 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0124 0.0876
Leishmania major cytochrome p450-like protein 0.0009 0.006 0.0392
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0009 0.006 0.0255
Loa Loa (eye worm) thioredoxin reductase 0.0041 0.0466 0.1186
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0728 0.1629
Trypanosoma cruzi DNA damage repair protein, putative 0.0006 0.0017 0.0065
Brugia malayi Patched protein homolog 1 0.0006 0.0017 0.0042
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.1164 0.2603
Schistosoma mansoni hypothetical protein 0.0356 0.4471 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0009 0.006 0.0392
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0109 0.133 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0176 0.1268
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0157 0.1126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0124 0.0876
Loa Loa (eye worm) hypothetical protein 0.0005 0.0008 0.0021
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0006 0.0022 0.0022
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0182 0.0463
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.3568 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0009 0.006 0.0392
Echinococcus granulosus cpg binding protein 0.0026 0.0279 0.0623
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Brugia malayi protein C24B5.3 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Echinococcus granulosus dna polymerase eta 0.0019 0.0182 0.0407
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1423 0.362
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0124 0.201
Trypanosoma brucei hypothetical protein, conserved 0.0006 0.0017 0.0065
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.1688 0.1688
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0087 0.1049 0.7875
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0617 0.138
Entamoeba histolytica protein kinase domain containing protein 0.0087 0.1049 0.2925
Plasmodium vivax glutathione reductase, putative 0.0041 0.0466 1
Echinococcus granulosus flap endonuclease GEN 1 0.0005 0.0008 0.0018
Brugia malayi MH2 domain containing protein 0.0008 0.0043 0.0111
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0104 0.127 0.7318
Echinococcus granulosus Smad4 0.0008 0.0043 0.0097
Brugia malayi Smad1 0.0008 0.0043 0.0111
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0182 0.0407
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0117 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0005 0.0008 0.0018
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) XPG I-region family protein 0.0005 0.0008 0.0021
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0009 0.006 0.0255
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0009 0.006 0.0255
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0041 0.0092
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0124 0.0325
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0157 0.1126
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0043 0.0097
Echinococcus granulosus smad 0.0008 0.0043 0.0097
Brugia malayi Muscleblind-like protein 0.0146 0.1795 0.4567
Echinococcus granulosus hypothetical protein 0.0027 0.028 0.0626
Echinococcus granulosus tar DNA binding protein 0.0062 0.0728 0.1629
Loa Loa (eye worm) hypothetical protein 0.0146 0.1795 0.4567
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0117 0.0117
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0104 0.127 0.7318
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0042
Brugia malayi RNA binding protein 0.0062 0.0728 0.1852
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0124 0.0876
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0109 0.133 1
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0009 0.006 0.0255
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.004 0.0101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0124 0.0876
Toxoplasma gondii patched family protein 0.0006 0.0017 0.0146
Brugia malayi XPG I-region family protein 0.0005 0.0008 0.0021
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0009 0.006 0.0255
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0009 0.006 0.0255
Brugia malayi Patched related family protein 4 0.0006 0.0017 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0006 0.0017 0.0065
Loa Loa (eye worm) tumor suppressor 0.0314 0.3931 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0182 0.1314
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.3568 1
Brugia malayi glutathione reductase 0.0041 0.0466 0.1186
Plasmodium falciparum DNA repair protein REV1, putative 0.0006 0.0017 0.0189
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0009 0.006 0.0255
Trypanosoma brucei unspecified product 0.0013 0.0108 0.0752
Brugia malayi Calcitonin receptor-like protein seb-1 0.0043 0.0494 0.1258
Trypanosoma brucei calpain, putative 0.0109 0.133 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) acetyltransferase 0.0126 0.1547 0.3936
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Brugia malayi polk-prov protein 0.0006 0.0017 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Echinococcus multilocularis 0.0009 0.006 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0109 0.133 1
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.1713 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0176 0.1268
Entamoeba histolytica hypothetical protein 0.0031 0.0341 0.0935
Schistosoma mansoni smad 0.0008 0.0043 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Entamoeba histolytica protein kinase, putative 0.0087 0.1049 0.2925
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0015 0.0018
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0182 0.0407
Schistosoma mansoni hypothetical protein 0.004 0.0448 0.1001
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0108 0.0752
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Schistosoma mansoni cpg binding protein 0.0025 0.0261 0.0583
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.3568 1
Brugia malayi Patched related family protein 10 0.0006 0.0017 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Echinococcus multilocularis flap endonuclease GEN 1 0.0005 0.0008 0.0008
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0037 0.0414 0.8873
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0124 0.0325
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0014 0.0124 0.5
Echinococcus multilocularis muscleblind protein 1 0.0146 0.1795 0.1795
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.1164 0.1164
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0182 0.0488
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0182 0.0973
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0266 0.1946
Schistosoma mansoni hypothetical protein 0.0014 0.0117 0.0262
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0031 0.0341 0.0341
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0266 0.0723
Echinococcus multilocularis protein quaking 0.0027 0.028 0.028
Echinococcus granulosus expressed conserved protein 0.009 0.109 0.2437
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0176 0.0471
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0728 0.1852
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0124 0.0876
Loa Loa (eye worm) glutathione reductase 0.0041 0.0466 0.1186
Echinococcus multilocularis protein dispatched 1 0.0047 0.0541 0.0541
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0124 0.2528
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0124 0.0876
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0094 0.1137 0.6512
Echinococcus granulosus muscleblind protein 0.0146 0.1795 0.4015
Echinococcus multilocularis expressed conserved protein 0.009 0.109 0.109
Leishmania major cytochrome p450-like protein 0.0017 0.0157 0.1126
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0009 0.006 0.0255
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.3568 1
Mycobacterium tuberculosis Probable reductase 0.0094 0.1137 0.6512
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0009 0.006 0.0255
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0124 0.0876
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0176 1
Brugia malayi Cytochrome P450 family protein 0.0042 0.0483 0.1228
Schistosoma mansoni hypothetical protein 0.0027 0.028 0.0626
Trypanosoma brucei DNA damage repair protein, putative 0.0006 0.0017 0.0065
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0087 0.1049 0.267
Schistosoma mansoni hypothetical protein 0.004 0.0448 0.1001
Brugia malayi MH2 domain containing protein 0.0116 0.1423 0.362
Loa Loa (eye worm) hypothetical protein 0.0087 0.1044 0.2655
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0124 0.0876
Schistosoma mansoni hypothetical protein 0.0009 0.006 0.0134
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0266 0.0723
Loa Loa (eye worm) cytochrome P450 family protein 0.0042 0.0483 0.1228
Trypanosoma brucei calpain-like protein, putative 0.0109 0.133 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0467 0.1187
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0109 0.133 1
Schistosoma mansoni hypothetical protein 0.0031 0.0341 0.0762
Brugia malayi hypothetical protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Leishmania major cytochrome p450-like protein 0.0009 0.006 0.0392
Schistosoma mansoni hypothetical protein 0.003 0.032 0.0715
Loa Loa (eye worm) Smad1 0.0008 0.0043 0.0111
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0005 0.0008 0.0008
Plasmodium falciparum histone acetyltransferase GCN5 0.0034 0.0375 0.8014
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0117 0.0262
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0176 0.0447
Brugia malayi tumor suppressor. 0.0314 0.3931 1
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0094 0.1137 0.6512
Loa Loa (eye worm) hypothetical protein 0.0005 0.0008 0.0021
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0015 0.0018
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0182 0.0973
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0006 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Schistosoma mansoni smad1 5 8 and 0.0008 0.0043 0.0097
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.3568 1
Plasmodium vivax thioredoxin reductase, putative 0.0041 0.0466 1
Schistosoma mansoni exonuclease 0.0005 0.0008 0.0018
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0728 0.1852
Giardia lamblia NADH oxidase lateral transfer candidate 0.0014 0.0124 0.0325
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0124 0.0876
Loa Loa (eye worm) CXXC zinc finger family protein 0.0025 0.0261 0.0663
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0009 0.006 0.0255
Brugia malayi hypothetical protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0041 0.0467 0.1187
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0124 0.0876
Brugia malayi Cytochrome P450 family protein 0.0017 0.0157 0.04
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0006 0.0017 0.015
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0087 0.1049 0.7875
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0009 0.006 0.0255
Brugia malayi hypothetical protein 0.0119 0.1462 0.3719
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0182 0.1314
Brugia malayi Myosin head containing protein 0.0006 0.0017 0.0042
Schistosoma mansoni patched 1 0.0041 0.0467 0.1044
Echinococcus multilocularis Smad4 0.0008 0.0043 0.0043
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0041 0.0466 0.2456
Echinococcus granulosus flap endonuclease 1 0.0025 0.0266 0.0594
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0031 0.0341 0.0762
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0182 0.0737
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0109 0.133 1
Leishmania major DNA polymerase eta, putative 0.0019 0.0182 0.1314
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Echinococcus multilocularis protein patched 0.0041 0.0467 0.0467
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0182 0.0463
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0176 0.0471
Plasmodium falciparum glutathione reductase 0.0041 0.0466 1
Brugia malayi Patched related family protein 12 0.0006 0.0017 0.0042
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0728 0.1852
Brugia malayi MH1 domain containing protein 0.0008 0.0043 0.0111
Loa Loa (eye worm) hypothetical protein 0.0008 0.004 0.0101
Echinococcus granulosus protein quaking 0.0027 0.028 0.0626
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0728 0.1629
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0006 0.0017 0.015
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Schistosoma mansoni flap endonuclease-1 0.0023 0.0235 0.0525
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Brugia malayi MH1 domain containing protein 0.0008 0.0043 0.0111
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0009 0.006 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Schistosoma mansoni hypothetical protein 0.0165 0.2044 0.4572
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0042
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0124 0.2528
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0266 0.0266
Schistosoma mansoni cpg binding protein 0.0026 0.0279 0.0623
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Echinococcus granulosus mixed lineage leukemia protein mll 0.0006 0.0022 0.0048
Loa Loa (eye worm) hypothetical protein 0.0019 0.0182 0.0463
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0027 0.028 0.0713
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0005 0.0008 0.0018
Toxoplasma gondii patched family protein 0.0006 0.0017 0.0146
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0266 0.0723
Schistosoma mansoni cytochrome P450 0.0009 0.006 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Schistosoma mansoni hypothetical protein 0.0027 0.028 0.0626
Echinococcus granulosus geminin 0.0165 0.2044 0.4572
Echinococcus granulosus dual specificity 0.0087 0.1049 0.2347
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0076 0.0193
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0176 0.0393
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0182 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0182 0.1314
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.0466 0.3463
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0096 0.1164 0.296
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0466 0.1042
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0124 0.0876
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0728 0.1629
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0043 0.0494 0.1258
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0109 0.133 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0109 0.133 1
Brugia malayi Flap endonuclease-1 0.0025 0.0266 0.0675
Echinococcus granulosus cytochrome P450 2K1 0.0009 0.006 0.0134
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0109 0.133 1
Brugia malayi hypothetical protein 0.0031 0.0341 0.0867
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0042
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0466 0.0466
Echinococcus multilocularis exonuclease 1 0.0005 0.0008 0.0008
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0266 0.0675
Giardia lamblia DINP protein human, muc B family 0.0019 0.0182 0.0488
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0014 0.0124 0.0631
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.1164 0.3246
Brugia malayi Temporarily assigned gene name protein 44 0.0027 0.028 0.0713
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0117 0.0298
Echinococcus granulosus GPCR family 2 0.0014 0.0117 0.0262
Brugia malayi Cytochrome P450 family protein 0.0009 0.006 0.0153
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.3568 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0182 0.0182
Entamoeba histolytica hypothetical protein 0.0087 0.1049 0.2925
Mycobacterium tuberculosis Probable oxidoreductase 0.0104 0.127 0.7318
Leishmania major DNA damage repair protein, putative 0.0006 0.0017 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0108 0.0752
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.3568 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Echinococcus granulosus histone acetyltransferase KAT2B 0.0037 0.0414 0.0927
Loa Loa (eye worm) patched family protein 0.0006 0.0017 0.0042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0015 0.0018
Trypanosoma brucei chrX additional, unordered contigs 0.0006 0.0017 0.0065
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0108 0.0752
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0006 0.0022 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0043 0.0111
Plasmodium vivax DNA repair protein REV1, putative 0.0006 0.0017 0.0189
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0087 0.1049 0.7875
Leishmania major DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0124 0.0315
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0009 0.006 0.0255
Entamoeba histolytica protein kinase, putative 0.0087 0.1049 0.2925
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Plasmodium falciparum lipid/sterol:H+ symporter 0.0006 0.0017 0.0184
Echinococcus multilocularis dual specificity 0.0087 0.1049 0.1049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0015 0.0018
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Echinococcus granulosus dnaJ subfamily B 0.0356 0.4471 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0182 0.0737
Brugia malayi acetyltransferase, GNAT family protein 0.0126 0.1547 0.3936
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0124 0.0124
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0109 0.133 1
Plasmodium falciparum thioredoxin reductase 0.0014 0.0124 0.2528
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0126 0.1547 0.1547
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0109 0.133 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0157 0.04
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0124 0.0876
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0182 0.0463
Brugia malayi CHE-14 protein 0.0041 0.0467 0.1187
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0182 0.0488
Schistosoma mansoni DNA polymerase IV / kappa 0.0006 0.0017 0.0038
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0182 0.1314
Brugia malayi TAR-binding protein 0.0062 0.0728 0.1852
Echinococcus granulosus exonuclease 1 0.0005 0.0008 0.0018
Schistosoma mansoni hypothetical protein 0.0165 0.2044 0.4572
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0176 0.1268
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0124 0.0876
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0009 0.006 0.0255
Loa Loa (eye worm) hypothetical protein 0.0119 0.1462 0.3719
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0124 0.0876
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0043 0.0097
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0009 0.006 0.0255
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0176 0.3661
Echinococcus multilocularis cpg binding protein 0.0026 0.0279 0.0279
Giardia lamblia Histone acetyltransferase GCN5 0.0034 0.0375 0.1031
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Trichomonas vaginalis helicase, putative 0.0006 0.0015 0.0018
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0009 0.006 0.0255
Brugia malayi MH2 domain containing protein 0.0008 0.0043 0.0111
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0182 0.1314
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0124 0.201
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0009 0.006 0.0255
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0009 0.006 0.0255
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0467 0.1044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.3568 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0015 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0006 0.0017 0.0065
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0037 0.0414 0.7052
Plasmodium falciparum glutathione reductase 0.0014 0.0124 0.2528
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0043 0.0043
Plasmodium vivax patched family protein, putative 0.0006 0.0017 0.0184
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0109 0.133 1
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0157 0.04
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0037 0.0414 0.1141
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0467 0.0467
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0124 0.0876
Toxoplasma gondii patched family protein 0.0006 0.0017 0.0146
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1423 0.362
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0015 0.0018
Schistosoma mansoni hypothetical protein 0.004 0.0448 0.1001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0176 0.3661
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0157 0.04
Brugia malayi cytochrome P450 0.0009 0.006 0.0153
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.1183 0.2645
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0182 0.1314
Entamoeba histolytica acetyltransferase, GNAT family 0.0034 0.0375 0.1031
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Toxoplasma gondii exonuclease III APE 0.0018 0.0176 0.291
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0094 0.1137 0.6512
Toxoplasma gondii hypothetical protein 0.0006 0.0017 0.0146
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0467 0.1044
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0104 0.127 0.7318
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Echinococcus multilocularis muscleblind protein 0.0146 0.1795 0.1795
Brugia malayi Cytochrome P450 family protein 0.0017 0.0157 0.04
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0124 0.0876
Toxoplasma gondii cytochrome p450 superfamily protein 0.0009 0.006 0.0901
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Leishmania major DNA polymerase eta, putative 0.0006 0.0017 0.0065
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0009 0.006 0.0255
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0006 0.0017 0.015
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0176 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0015 0.0018
Plasmodium falciparum flap endonuclease 1 0.0025 0.0266 0.562
Schistosoma mansoni hypothetical protein 0.0014 0.0117 0.0262
Entamoeba histolytica hypothetical protein 0.0031 0.0341 0.0935
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0266 0.4467
Trypanosoma cruzi DNA polymerase eta, putative 0.0006 0.0017 0.0065
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0182 0.1314
Trypanosoma cruzi hypothetical protein, conserved 0.0006 0.0017 0.0065
Schistosoma mansoni ap endonuclease 0.0018 0.0176 0.0393
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0043 0.0494 0.1258
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0728 0.1629
Echinococcus granulosus histone acetyltransferase KAT2B 0.0123 0.1502 0.336
Brugia malayi Thioredoxin reductase 0.0041 0.0466 0.1186
Schistosoma mansoni smad1 5 8 and 0.0008 0.0043 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0467 0.1288
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0126 0.1547 0.3461
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0109 0.133 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0006 0.0022 0.0048
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0157 0.1126
Mycobacterium tuberculosis Probable dehydrogenase 0.0094 0.1137 0.6512
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0109 0.133 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0117 0.0262
Giardia lamblia DNA damage repair protein 0.0006 0.0017 0.0024
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0176 0.1268
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0124 0.0277
Trypanosoma brucei unspecified product 0.0019 0.0182 0.1314
Schistosoma mansoni hypothetical protein 0.0014 0.0117 0.0262
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0124 0.0876
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Loa Loa (eye worm) hypothetical protein 0.0087 0.1044 0.2655
Brugia malayi Patched family protein 0.0006 0.0017 0.0042
Schistosoma mansoni Smad4 0.0008 0.0043 0.0097
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0728 0.0728
Trypanosoma cruzi DNA damage repair protein, putative 0.0006 0.0017 0.0065
Loa Loa (eye worm) cytochrome P450 0.0009 0.006 0.0153
Echinococcus multilocularis smad 0.0008 0.0043 0.0043
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0043 0.0111
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0117 0.0298
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0043 0.0043
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.1713 1
Loa Loa (eye worm) hypothetical protein 0.003 0.032 0.0814
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0014 0.0124 0.0631
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0015 0.0018
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0037 0.0414 0.7052
Trypanosoma brucei hypothetical protein, conserved 0.0006 0.0017 0.0065
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0076 0.0193
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0042
Plasmodium falciparum thioredoxin reductase 0.0041 0.0466 1
Onchocerca volvulus 0.0025 0.0261 0.1687
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.1049 0.2347
Brugia malayi hypothetical protein 0.0027 0.028 0.0713
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0009 0.006 0.0392
Schistosoma mansoni ap endonuclease 0.0018 0.0176 0.0393
Brugia malayi hypothetical protein 0.0006 0.0017 0.0042
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0043 0.0494 0.1258
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0009 0.006 0.0255
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0266 0.1946
Entamoeba histolytica hypothetical protein 0.0031 0.0341 0.0935
Entamoeba histolytica hypothetical protein 0.0031 0.0341 0.0935
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0015 0.0018
Leishmania major DNA polymerase kappa, putative 0.0006 0.0017 0.0065
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.1688 0.3775
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0124 0.2528
Echinococcus multilocularis dna polymerase eta 0.0019 0.0182 0.0182
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0182 0.0407
Trypanosoma brucei DNA damage repair protein, putative 0.0006 0.0017 0.0065
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0014 0.0124 0.0386

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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