TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 468.494 | Formula: C22H30F2N4O5
H donors: 4 H acceptors: 3 LogP: 0.48 Rotable bonds: 12
Rule of 5 violations (Lipinski): 1
SMILES: OC[C@@H]1O[C@@H](C=C[C@H]1NC(=O)Nc1cc(F)ccc1F)CC(=O)NCCCN1CCOCC1
InChi: 1S/C22H30F2N4O5/c23-15-2-4-17(24)19(12-15)27-22(31)26-18-5-3-16(33-20(18)14-29)13-21(30)25-6-1-7-28-8-10-32-11-9-28/h2-5,12,16,18,20,29H,1,6-11,13-14H2,(H,25,30)(H2,26,27,31)/t16-,18+,20-/m0/s1
InChiKey: BZALQHWMPIGLLK-HQRMLTQVSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	hypothetical protein	0.0074	0.0531	0.0566
Echinococcus granulosus	tumor protein p63	0.0382	0.5476	0.5476
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0088	0.0763	0.5
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0075	0.0551	0.0551
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0113	0.1155	0.1341
Echinococcus multilocularis	Netrin receptor DCC	0.0165	0.1991	0.1991
Trypanosoma brucei	protein kinase, putative	0.0075	0.0551	0.0136
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Loa Loa (eye worm)	acetyltransferase	0.017	0.2068	0.2305
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0412	0.5966	0.6363
Echinococcus multilocularis	fibronectin type III domain-containing protein	0.0165	0.1991	0.1991
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Schistosoma mansoni	myosin-binding protein-related	0.0204	0.2615	0.2789
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0577	0.8612	1
Echinococcus granulosus	low density lipoprotein receptor ldl	0.0048	0.0108	0.0108
Loa Loa (eye worm)	CAMK/CAMKL/NUAK protein kinase	0.0491	0.7229	0.8373
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0204	0.2615	0.3036
Onchocerca volvulus		0.0205	0.2635	0.3108
Brugia malayi	C-terminal src kinase protein 1	0.0074	0.0531	0.0616
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0048	0.0108	0.0125
Trypanosoma cruzi	hypothetical protein, conserved	0.0165	0.1991	1
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0252	0.3398	0.3869
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0067	0.0428	0.0456
Loa Loa (eye worm)	CAMK protein kinase	0.0205	0.2635	0.2971
Onchocerca volvulus		0.0074	0.0531	0.0375
Onchocerca volvulus		0.0165	0.1991	0.2271
Schistosoma mansoni	cell adhesion molecule	0.0251	0.3379	0.3603
Echinococcus granulosus	activated cdc42 kinase 1	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0732	0.0734
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0074	0.0531	0.0531
Loa Loa (eye worm)	MH2 domain-containing protein	0.014	0.1588	0.1741
Entamoeba histolytica	cysteine surface protein, putative	0.0074	0.0531	0.9121
Onchocerca volvulus		0.0165	0.1991	0.2271
Brugia malayi	Peroxidasin	0.0087	0.0735	0.0854
Schistosoma mansoni	cell adhesion molecule	0.0048	0.0108	0.0115
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	TK/INSR protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Onchocerca volvulus		0.0165	0.1991	0.2271
Loa Loa (eye worm)	hypothetical protein	0.0577	0.8612	1
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0428	0.0376
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0111	0.1135	0.1207
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0086	0.0732	0.085
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0531	0.0494
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0074	0.0531	0.0531
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0412	0.5966	0.5966
Brugia malayi	Furin-like cysteine rich region family protein	0.0074	0.0531	0.0616
Onchocerca volvulus		0.0074	0.0531	0.0375
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Entamoeba histolytica	acetyltransferase, GNAT family	0.0046	0.0079	0.1352
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0074	0.0531	0.0531
Brugia malayi	basement membrane proteoglycan	0.0048	0.0108	0.0125
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Echinococcus granulosus	usherin	0.0165	0.1991	0.1991
Schistosoma mansoni	protein kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	TK protein kinase	0.0113	0.1155	0.1231
Entamoeba histolytica	tyrosin kinase, putative	0.0077	0.0582	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Echinococcus multilocularis	peroxidasin	0.0087	0.0735	0.0735
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0074	0.0531	0.0497
Echinococcus multilocularis	Phosphotidylinositol phosphatase PTPRQ	0.0165	0.1991	0.1991
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0075	0.0551	0.0136
Entamoeba histolytica	hypothetical protein	0.0074	0.0531	0.9121
Echinococcus granulosus	hemicentin 1	0.0086	0.0732	0.0732
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.046	0.6729	0.7786
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	cell adhesion molecule	0.0165	0.1991	0.1991
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Entamoeba histolytica	receptor protein kinase, putative	0.0074	0.0531	0.9121
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0763	0.0771
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0531	0.0494
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0074	0.0531	0.0531
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Schistosoma mansoni	tyrosine protein kinase	0.0074	0.0531	0.0566
Echinococcus multilocularis	roundabout 2	0.0663	1	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0074	0.0531	0.9121
Echinococcus multilocularis	titin	0.0205	0.2635	0.2635
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0074	0.0531	0.0531
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0165	0.1991	0.1991
Echinococcus multilocularis	protein kinase	0.0074	0.0531	0.0531
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0251	0.3379	0.3379
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Schistosoma mansoni	neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule	0.0048	0.0108	0.0115
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0074	0.0531	0.0531
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0074	0.0531	0.6233
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0074	0.0531	0.0494
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0074	0.0531	0.0566
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0239	0.3177	0.3177
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0531	0.0494
Brugia malayi	hypothetical protein	0.0074	0.0531	0.0616
Entamoeba histolytica	ankyrin repeat protein	0.0074	0.0531	0.9121
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0065	0.0388	0.0388
Echinococcus granulosus	Netrin receptor DCC	0.0165	0.1991	0.1991
Entamoeba histolytica	hypothetical protein	0.0074	0.0531	0.9121
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0204	0.2615	0.3036
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0165	0.1991	0.2123
Onchocerca volvulus		0.0204	0.2615	0.3082
Echinococcus multilocularis	Immunoglobulin	0.0412	0.5966	0.5966
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0074	0.0531	0.0497
Echinococcus granulosus	protein tyrosine kinase	0.0074	0.0531	0.0531
Echinococcus granulosus	roundabout 2	0.0251	0.3379	0.3379
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0074	0.0531	0.6233
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0113	0.1155	0.1155
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0074	0.0531	0.0531
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0074	0.0531	0.0531
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0074	0.0531	0.0531
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	histone acetyltransferase KAT2B	0.005	0.0145	0.0145
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Entamoeba histolytica	protein kinase domain containing protein	0.0077	0.0582	1
Schistosoma mansoni	protein kinase	0.0075	0.0551	0.0587
Trichomonas vaginalis	TK family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0074	0.0531	0.0531
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0531	0.0494
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Schistosoma mansoni	serine/threonine protein kinase	0.0074	0.0531	0.0566
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0074	0.0531	0.0531
Echinococcus granulosus	protein kinase	0.0074	0.0531	0.0531
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus granulosus	tyrosine protein kinase csk	0.0074	0.0531	0.0531
Schistosoma mansoni	protein kinase	0.0074	0.0531	0.0566
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0111	0.1135	0.1317
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Schistosoma mansoni	cellular tumor antigen P53	0.0056	0.0242	0.0258
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0075	0.0551	0.0551
Schistosoma mansoni	nephrin related	0.0048	0.0108	0.0115
Schistosoma mansoni	hypothetical protein	0.0048	0.0108	0.0115
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0165	0.1991	0.2214
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus granulosus	tyrosine protein kinase pr2	0.0074	0.0531	0.0531
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0048	0.0108	0.0108
Schistosoma mansoni	titin	0.0204	0.2615	0.2789
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0074	0.0531	0.0494
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Brugia malayi	protein-tyrosine kinase	0.0074	0.0531	0.0616
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0075	0.0551	0.0551
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Schistosoma mansoni	titin	0.0086	0.0732	0.0781
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0074	0.0531	0.0531
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0067	0.0428	0.0456
Schistosoma mansoni	receptor protein tyrosine phosphatase	0.0165	0.1991	0.2123
Brugia malayi	Pre-SET motif family protein	0.047	0.6898	0.801
Brugia malayi	Prion-like-	0.0086	0.0732	0.085
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0251	0.3379	0.3923
Loa Loa (eye worm)	hypothetical protein	0.0499	0.7353	0.852
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	TK/ACK protein kinase	0.0074	0.0531	0.0497
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0074	0.0531	0.0531
Entamoeba histolytica	serine/threonine kinase, putative	0.0074	0.0531	0.9121
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Loa Loa (eye worm)	hypothetical protein	0.0056	0.0242	0.0158
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 32	0.0165	0.1991	0.2312
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0111	0.1135	0.1317
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0533	0.7916	0.9191
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0088	0.0763	1
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0074	0.0531	0.0531
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0568	0.0541
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0086	0.0732	0.085
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0074	0.0531	0.0616
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0251	0.3379	0.3379
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0629	0.9456	0.9456
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0074	0.0531	0.6233
Echinococcus granulosus	titin	0.0205	0.2635	0.2635
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0074	0.0531	0.0497
Brugia malayi	Fibronectin type III domain containing protein	0.0165	0.1991	0.2312
Loa Loa (eye worm)	TK/ALK protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	TK/FAK protein kinase	0.0074	0.0531	0.0497
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0088	0.0763	1
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0165	0.1991	0.1991
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0048	0.0108	0.0115
Plasmodium vivax	SET domain protein, putative	0.0067	0.0428	0.4569
Loa Loa (eye worm)	TK/Met protein kinase	0.0074	0.0531	0.0497
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0074	0.0531	0.0531
Schistosoma mansoni	cell adhesion molecule	0.0204	0.2615	0.2789
Brugia malayi	MH2 domain containing protein	0.014	0.1588	0.1844
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	hypothetical protein	0.0165	0.1991	0.2312
Schistosoma mansoni	neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule	0.0086	0.0732	0.0781
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0412	0.5966	0.6363
Echinococcus granulosus	tyrosine protein kinase Srms	0.0074	0.0531	0.0531
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0074	0.0531	0.0531
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0074	0.0531	0.0531
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0251	0.3379	0.3379
Trichomonas vaginalis	AGC family protein kinase	0.0074	0.0531	0.0494
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus granulosus	tyrosine kinase	0.0074	0.0531	0.0531
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0074	0.0531	0.0497
Schistosoma mansoni	protein kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Schistosoma mansoni	titin	0.0205	0.2635	0.281
Echinococcus multilocularis	cell adhesion molecule:down regulated by	0.0048	0.0108	0.0108
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	neuroglian	0.0451	0.659	0.659
Plasmodium falciparum	tyrosine kinase-like protein	0.0074	0.0531	0.66
Plasmodium falciparum	protein kinase, putative	0.0075	0.0551	0.6891
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0075	0.0551	0.0136
Brugia malayi	Immunoglobulin domain containing protein	0.0048	0.0108	0.0125
Schistosoma mansoni	protein tyrosine kinase	0.0074	0.0531	0.0566
Toxoplasma gondii	STE kinase	0.0074	0.0531	0.6233
Onchocerca volvulus		0.0165	0.1991	0.2271
Schistosoma mansoni	serine/threonine RGC	0.0074	0.0531	0.0566
Schistosoma mansoni	hypothetical protein	0.0048	0.0108	0.0115
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Echinococcus multilocularis	activated cdc42 kinase 1	0.0074	0.0531	0.0531
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Entamoeba histolytica	hypothetical protein, conserved	0.0074	0.0531	0.9121
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Echinococcus multilocularis	FL cytokine receptor	0.0074	0.0531	0.0531
Entamoeba histolytica	serine/threonine kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0074	0.0531	0.0566
Schistosoma mansoni	tyrosine kinase	0.016	0.1918	0.2046
Schistosoma mansoni	protein kinase	0.0074	0.0531	0.0566
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Loa Loa (eye worm)	hypothetical protein	0.0499	0.7353	0.852
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus multilocularis	c src tyrosine kinase	0.0074	0.0531	0.0531
Loa Loa (eye worm)	TK/CSK protein kinase	0.0074	0.0531	0.0497
Echinococcus multilocularis	low density lipoprotein receptor (ldl)	0.0048	0.0108	0.0108
Plasmodium falciparum	protein kinase, putative	0.0074	0.0531	0.66
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0074	0.0531	0.0531
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0251	0.3379	0.3923
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	tyrosine kinase	0.0074	0.0531	0.0531
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0531	0.0494
Loa Loa (eye worm)	hypothetical protein	0.0204	0.2615	0.2948
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Echinococcus granulosus	Down syndrome cell adhesion molecule	0.0212	0.2754	0.2754
Echinococcus multilocularis	usherin	0.0165	0.1991	0.1991
Entamoeba histolytica	protein kinase domain containing protein	0.0075	0.0551	0.9463
Loa Loa (eye worm)	hypothetical protein	0.0462	0.6763	0.7826
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0074	0.0531	0.0616
Onchocerca volvulus		0.0165	0.1991	0.2271
Echinococcus granulosus	twitchin	0.0452	0.661	0.661
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Echinococcus granulosus	Immunoglobulin	0.0412	0.5966	0.5966
Loa Loa (eye worm)	serine/threonine protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Brugia malayi	Heparan sulfate	0.0048	0.0108	0.0125
Entamoeba histolytica	protein kinase, putative	0.0074	0.0534	0.9177
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0074	0.0531	0.0531
Echinococcus multilocularis	contactin neuroglian septate junction protein	0.0251	0.3379	0.3379
Echinococcus granulosus	Fibronectin type III	0.0165	0.1991	0.1991
Onchocerca volvulus		0.0074	0.0531	0.0375
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0074	0.0531	0.0497
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	anosmin 1	0.0165	0.1991	0.1991
Loa Loa (eye worm)	hypothetical protein	0.0577	0.8612	1
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus granulosus	Immunoglobulin	0.0048	0.0108	0.0108
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.0088	0.0763	0.0763
Brugia malayi	hypothetical protein	0.0048	0.0108	0.0125
Schistosoma mansoni	nephrin	0.0616	0.9236	0.9851
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0074	0.0531	0.0497
Onchocerca volvulus		0.0074	0.0531	0.0375
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus multilocularis	Immunoglobulin	0.0048	0.0108	0.0108
Brugia malayi	Lethal protein 805	0.0165	0.1991	0.2312
Schistosoma mansoni	serine/threonine protein kinase	0.0074	0.0531	0.0566
Onchocerca volvulus		0.0074	0.0531	0.0375
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Trypanosoma cruzi	Fibronectin type III domain containing protein, putative	0.0165	0.1991	1
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	3'partial\|cell adhesion molecule:down regulated by	0.0048	0.0108	0.0108
Echinococcus multilocularis	tyrosine kinase	0.0074	0.0531	0.0531
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0074	0.0531	0.0531
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Schistosoma mansoni	basigin related	0.0048	0.0108	0.0115
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0251	0.3379	0.3846
Schistosoma mansoni	factor for adipocyte differentiation	0.0165	0.1991	0.2123
Loa Loa (eye worm)	hypothetical protein	0.0251	0.3379	0.3846
Echinococcus granulosus	tyrosine protein kinase shark	0.0074	0.0531	0.0531
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Entamoeba histolytica	hypothetical protein	0.0074	0.0534	0.9177
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	peroxidasin	0.0048	0.0111	0.0118
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0067	0.0428	0.4569
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	myotactin form A	0.0165	0.1991	0.2214
Brugia malayi	ephrin receptor 1 precursor	0.0074	0.0531	0.0616
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0533	0.7916	0.9181
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Brugia malayi	Pre-SET motif family protein	0.0067	0.0428	0.0497
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Tyrosine-protein kinase PR2	0.0074	0.0531	0.0616
Echinococcus multilocularis	tyrosine protein kinase csk	0.0074	0.0531	0.0531
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0088	0.0763	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0074	0.0531	0.0531
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0074	0.0531	0.0531
Schistosoma mansoni	basigin related	0.0048	0.0108	0.0115
Onchocerca volvulus		0.0074	0.0531	0.0375
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0074	0.0531	0.0566
Entamoeba histolytica	hypothetical protein	0.0074	0.0531	0.9121
Echinococcus multilocularis	protein tyrosine kinase	0.0074	0.0531	0.0531
Brugia malayi	protein unc-22	0.0205	0.2635	0.3059
Brugia malayi	Fibronectin type III domain containing protein	0.0577	0.8612	1
Echinococcus multilocularis	hemicentin 1	0.0086	0.0732	0.0732
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Echinococcus granulosus	fibronectin type III domain-containing protein	0.0165	0.1991	0.1991
Entamoeba histolytica	ankyrin repeat protein	0.0074	0.0531	0.9121
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Echinococcus granulosus	tyrosine protein kinase Blk	0.0074	0.0531	0.0531
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Schistosoma mansoni	gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2	0.017	0.2068	0.2206
Brugia malayi	Receptor family ligand binding region containing protein	0.0074	0.0531	0.0616
Echinococcus multilocularis	neurotracting:lsamp:neurotrimin:obcam	0.0086	0.0732	0.0732
Plasmodium vivax	protein kinase, putative	0.0074	0.0531	0.6233
Echinococcus granulosus	activated cdc42 kinase 1	0.0074	0.0531	0.0531
Trypanosoma cruzi	Fibronectin type III domain containing protein, putative	0.0165	0.1991	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0204	0.2615	0.3036
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Echinococcus granulosus	tyrosine kinase	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Brugia malayi	Fibronectin type III domain containing protein	0.0165	0.1991	0.2312
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	EG95	0.0165	0.1991	0.1991
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0088	0.0763	0.5
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0088	0.0763	1
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus granulosus	anosmin 1	0.0165	0.1991	0.1991
Echinococcus granulosus	anosmin 1	0.0165	0.1991	0.1991
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0531	0.0494
Onchocerca volvulus		0.0074	0.0531	0.0375
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0251	0.3379	0.3603
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0204	0.2615	0.3036
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Echinococcus granulosus	nephrin	0.0204	0.2615	0.2615
Trypanosoma brucei	Fibronectin type III domain containing protein, putative	0.0165	0.1991	1
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0074	0.0531	0.0531
Echinococcus granulosus	Phosphotidylinositol phosphatase PTPRQ	0.0165	0.1991	0.1991
Echinococcus granulosus	epidermal growth factor receptor	0.0074	0.0531	0.0531
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0086	0.0732	0.0734
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Schistosoma mansoni	basigin related	0.0048	0.0108	0.0115
Trichomonas vaginalis	conserved hypothetical protein	0.0074	0.0531	0.0494
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0074	0.0531	0.0531
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0205	0.2635	0.3059
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	set domain proteins, putative	0.0535	0.7942	1
Schistosoma mansoni	septate junction protein	0.0086	0.0732	0.0781
Echinococcus granulosus	netrin receptor unc 5	0.0048	0.0108	0.0108
Schistosoma mansoni	cell adhesion molecule	0.0204	0.2615	0.2789
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.046	0.6729	0.6729
Echinococcus granulosus	titin	0.0205	0.2635	0.2635
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Echinococcus granulosus	anosmin 1	0.0165	0.1991	0.1991
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0048	0.0108	0.0125
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Echinococcus granulosus	STE20 serine:threonine protein kinase	0.0463	0.6783	0.6783
Echinococcus multilocularis	integrin linked protein kinase	0.0074	0.0531	0.0531
Brugia malayi	Immunoglobulin domain containing protein	0.0048	0.0108	0.0125
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0074	0.0531	0.0531
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	epidermal growth factor receptor	0.0074	0.0531	0.0531
Loa Loa (eye worm)	TK/RYK protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0204	0.2615	0.3036
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0074	0.0531	0.0566
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Entamoeba histolytica	hypothetical protein	0.0074	0.0531	0.9121
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0212	0.2754	0.3198
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0165	0.1991	0.1991
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0074	0.0531	0.0375
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0732	0.0734
Entamoeba histolytica	hypothetical protein	0.0074	0.0531	0.9121
Schistosoma mansoni	peptidase Clp (S14 family)	0.0088	0.0763	0.0814
Loa Loa (eye worm)	transcription factor SMAD2	0.014	0.1588	0.1741
Echinococcus granulosus	lachesin	0.0086	0.0732	0.0732
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0074	0.0531	0.0616
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0204	0.2615	0.2948
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Onchocerca volvulus		0.0165	0.1991	0.2271
Onchocerca volvulus		0.0074	0.0531	0.0375
Schistosoma mansoni	hypothetical protein	0.0048	0.0108	0.0115
Echinococcus multilocularis	STE20 serine:threonine protein kinase	0.0463	0.6783	0.6783
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0074	0.0531	0.0531
Brugia malayi	myotactin form A	0.0165	0.1991	0.2312
Schistosoma mansoni	protein kinase	0.0074	0.0531	0.0566
Echinococcus granulosus	kinase suppressor of Ras 1	0.0074	0.0531	0.0531
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP)	0.0058	0.0275	0.5
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Entamoeba histolytica	tyrosin kinase, putative	0.0074	0.0531	0.9121
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0074	0.0531	0.0531
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Loa Loa (eye worm)	TK/EPH protein kinase	0.0074	0.0531	0.0497
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0074	0.0531	0.0531
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.0088	0.0763	0.5
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Echinococcus granulosus	neuroglian	0.0251	0.3379	0.3379
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0048	0.0108	0.0125
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	SH2 domain containing protein	0.0074	0.0531	0.0616
Schistosoma mansoni	hemicentin	0.0204	0.2615	0.2789
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus multilocularis	tyrosine protein kinase csk	0.0074	0.0531	0.0531
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Echinococcus multilocularis	netrin receptor unc 5	0.0048	0.0108	0.0108
Echinococcus multilocularis	tyrosine protein kinase otk	0.0086	0.0732	0.0732
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0165	0.1991	0.2214
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0074	0.0531	0.0497
Brugia malayi	hypothetical protein	0.0074	0.0531	0.0616
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus multilocularis	tyrosine protein kinase csk	0.0074	0.0531	0.0531
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus granulosus	cell adhesion molecule	0.0165	0.1991	0.1991
Loa Loa (eye worm)	TK/DDR protein kinase	0.0074	0.0531	0.0497
Brugia malayi	Guanylyl cyclase protein 23	0.0074	0.0531	0.0616
Schistosoma mansoni	netrin receptor unc5	0.0048	0.0108	0.0115
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0074	0.0531	0.9121
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0075	0.0551	0.6555
Echinococcus multilocularis	gcn5proteinral control of amino acid synthesis	0.017	0.2068	0.2068
Echinococcus granulosus	integrin linked protein kinase	0.0074	0.0531	0.0531
Brugia malayi	acetyltransferase, GNAT family protein	0.017	0.2068	0.2402
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0086	0.0732	0.085
Echinococcus granulosus	Phosphotidylinositol phosphatase PTPRQ	0.0165	0.1991	0.1991
Brugia malayi	Probable ClpP-like protease	0.0088	0.0763	0.0887
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Schistosoma mansoni	factor for adipocyte differentiation	0.0165	0.1991	0.2123
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0732	0.0734
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus multilocularis	Fibronectin type III domain containing protein	0.0165	0.1991	0.1991
Schistosoma mansoni	cell adhesion molecule	0.0251	0.3379	0.3603
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 30.	0.0165	0.1991	0.2312
Onchocerca volvulus	Tyrosine kinase homolog	0.0113	0.1155	0.1186
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0165	0.1991	0.2214
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0074	0.0531	0.0531
Echinococcus granulosus	Fibronectin type III domain containing protein	0.0165	0.1991	0.1991
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Schistosoma mansoni	tripartite motif protein trim9	0.0165	0.1991	0.2123
Entamoeba histolytica	serine/threonine kinase, putative	0.0074	0.0531	0.9121
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0074	0.0531	0.6233
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0113	0.1155	0.1155
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0074	0.0531	0.0531
Brugia malayi	Tyrosine-protein kinase abl-1	0.0074	0.0531	0.0616
Echinococcus multilocularis	anosmin 1	0.0165	0.1991	0.1991
Loa Loa (eye worm)	projectin	0.0204	0.2615	0.2948
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	tyrosine protein kinase	0.0074	0.0531	0.0531
Echinococcus multilocularis	tyrosine protein kinase shark	0.0074	0.0531	0.0531
Loa Loa (eye worm)	TK protein kinase	0.0074	0.0531	0.0497
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Schistosoma mansoni	ephrin receptor	0.0074	0.0531	0.0566
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0074	0.0531	0.0531
Onchocerca volvulus		0.0165	0.1991	0.2271
Entamoeba histolytica	tyrosin kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0067	0.0428	0.0456
Onchocerca volvulus		0.0535	0.7942	1
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Echinococcus multilocularis	tyrosine protein kinase csk	0.0074	0.0531	0.0531
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0239	0.3177	0.3177
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.0088	0.0763	0.0763
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0086	0.0732	0.085
Schistosoma mansoni	neuroglian	0.0251	0.3379	0.3603
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0075	0.0551	0.0136
Echinococcus multilocularis	Immunoglobulin	0.0412	0.5966	0.5966
Echinococcus granulosus	roundabout 2	0.0251	0.3379	0.3379
Schistosoma mansoni	septate junction protein	0.0048	0.0108	0.0115
Brugia malayi	latrophilin 2 splice variant baaae	0.0076	0.0568	0.066
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Toxoplasma gondii	protein kinase	0.0074	0.0531	0.6233
Loa Loa (eye worm)	hypothetical protein	0.0412	0.5969	0.6892
Schistosoma mansoni	cell adhesion molecule	0.0624	0.9376	1
Brugia malayi	Fibronectin type III domain containing protein	0.0165	0.1991	0.2312
Echinococcus granulosus	tyrosine protein kinase HCK	0.0074	0.0531	0.0531
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0067	0.0428	0.0428
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0074	0.0531	0.0531
Onchocerca volvulus		0.0074	0.0531	0.0375
Echinococcus multilocularis	tyrosine protein kinase	0.0074	0.0531	0.0531
Echinococcus granulosus	natriuretic peptide receptor 1	0.0074	0.0531	0.0531
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0204	0.2615	0.2948
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0074	0.0531	0.0566
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0074	0.0531	0.0531
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Schistosoma mansoni	netrin receptor unc5	0.0048	0.0108	0.0115
Schistosoma mansoni	hypothetical protein	0.0204	0.2615	0.2789
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	hypothetical protein	0.0111	0.1135	0.1207
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Onchocerca volvulus		0.0074	0.0531	0.0375
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Schistosoma mansoni	protein kinase	0.0074	0.0531	0.0566
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0165	0.1991	0.2123
Entamoeba histolytica	hypothetical protein	0.0074	0.0534	0.9177
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	serine/threonine kinase, putative	0.0074	0.0531	0.9121
Echinococcus granulosus	insulin receptor	0.0074	0.0531	0.0531
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Brugia malayi	myotactin form B	0.0165	0.1991	0.2312
Entamoeba histolytica	hypothetical protein	0.0074	0.0531	0.9121
Echinococcus granulosus	basement membrane specific heparan sulfate	0.0048	0.0108	0.0108
Schistosoma mansoni	nephrin	0.0251	0.3379	0.3603
Trichomonas vaginalis	STE family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	tyrosine kinase	0.0074	0.0531	0.0531
Echinococcus granulosus	Netrin receptor DCC	0.0165	0.1991	0.1991
Echinococcus multilocularis	neuroglian	0.0251	0.3379	0.3379
Entamoeba histolytica	hypothetical protein	0.0074	0.0531	0.9121
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0251	0.3379	0.3379
Schistosoma mansoni	hypothetical protein	0.0165	0.1991	0.2123
Giardia lamblia	Kinase, NEK	0.0074	0.0531	1
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus multilocularis	transfer RNA-Phe	0.0204	0.2615	0.2615
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	epidermal growth factor receptor	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Onchocerca volvulus		0.0067	0.0428	0.0241
Toxoplasma gondii	protein kinase domain-containing protein	0.0074	0.0531	0.6233
Onchocerca volvulus		0.0165	0.1991	0.2271
Echinococcus multilocularis	Immunoglobulin	0.0048	0.0108	0.0108
Schistosoma mansoni	serine/threonine protein kinase	0.0074	0.0531	0.0566
Echinococcus granulosus	tyrosine protein kinase csk	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0204	0.2615	0.2948
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0088	0.0763	0.5
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0074	0.0531	0.0531
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0074	0.0531	0.0497
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	hypothetical protein	0.0577	0.8612	1
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0074	0.0531	0.0531
Leishmania major	protein kinase, putative	0.0075	0.0551	0.0136
Onchocerca volvulus		0.0165	0.1991	0.2271
Giardia lamblia	Kinase	0.0074	0.0531	1
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Brugia malayi	Raf kinase	0.0074	0.0531	0.0616
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0212	0.2754	0.3112
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0052	0.0179	0.0083
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0074	0.0531	0.0531
Schistosoma mansoni	protein kinase	0.0075	0.0551	0.0587
Brugia malayi	hypothetical protein	0.0074	0.0531	0.0616
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0048	0.0108	0.0115
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Echinococcus granulosus	G1Y162 protein	0.0165	0.1991	0.1991
Echinococcus granulosus	histone acetyltransferase KAT2B	0.0165	0.1992	0.1992
Loa Loa (eye worm)	TK/ROR protein kinase	0.0113	0.1155	0.1231
Schistosoma mansoni	protein kinase	0.0074	0.0531	0.0566
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	Down syndrome cell adhesion molecule	0.0212	0.2754	0.2754
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus multilocularis	lachesin	0.0086	0.0732	0.0732
Echinococcus multilocularis	hemicentin 1	0.0086	0.0732	0.0732
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0165	0.1991	0.1991
Echinococcus multilocularis	peptidase Clp (S14 family)	0.0058	0.0275	0.0275
Echinococcus granulosus	pro neuregulin 2 membrane bound	0.0048	0.0108	0.0108
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0074	0.0531	0.0531
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0251	0.3379	0.3923
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0074	0.0531	0.0531
Onchocerca volvulus		0.0074	0.0531	0.0375
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus multilocularis	Netrin receptor DCC	0.0165	0.1991	0.1991
Onchocerca volvulus		0.0165	0.1991	0.2271
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0074	0.0531	0.0531
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0086	0.0732	0.085
Echinococcus multilocularis	roundabout 2	0.0251	0.3379	0.3379
Entamoeba histolytica	serine/threonine kinase, putative	0.0074	0.0531	0.9121
Brugia malayi	Immunoglobulin domain containing protein	0.0048	0.0108	0.0125
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0074	0.0531	0.0531
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0074	0.0531	0.0531
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0732	0.0734
Schistosoma mansoni	roundabout	0.0086	0.0732	0.0781
Schistosoma mansoni	cell adhesion molecule	0.0048	0.0108	0.0115
Echinococcus granulosus	neuroglian	0.0451	0.659	0.659
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Echinococcus granulosus	tyrosine protein kinase csk	0.0074	0.0531	0.0531
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0074	0.0531	0.0531
Schistosoma mansoni	ephrin receptor	0.0239	0.3177	0.3389
Schistosoma mansoni	hypothetical protein	0.0048	0.0108	0.0115
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Echinococcus multilocularis	protein kinase	0.0074	0.0531	0.0531
Schistosoma mansoni	protein kinase	0.0074	0.0531	0.0566
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Entamoeba histolytica	hypothetical protein	0.0074	0.0531	0.9121
Schistosoma mansoni	hypothetical protein	0.0048	0.0108	0.0115
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0205	0.2635	0.2971
Echinococcus granulosus	tyrosine protein kinase otk	0.0086	0.0732	0.0732
Echinococcus granulosus	c src tyrosine kinase	0.0074	0.0531	0.0531
Echinococcus multilocularis	insulin receptor	0.0074	0.0531	0.0531
Brugia malayi	protein-tyrosine phosphatase Lar-like precursor, putative	0.0165	0.1991	0.2312
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Echinococcus multilocularis	anosmin 1	0.0165	0.1991	0.1991
Brugia malayi	Protein-tyrosine phosphatase	0.0165	0.1991	0.2312
Schistosoma mansoni	cell adhesion molecule	0.0086	0.0732	0.0781
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Plasmodium falciparum	protein kinase, putative	0.0074	0.0531	0.66
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	protein kinase atn1, putative	0.0074	0.0531	0.0494
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0067	0.0428	0.0456
Echinococcus multilocularis	tumor protein p63	0.0382	0.5476	0.5476
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	histone lysine methyltransferase setb	0.0067	0.0428	0.0428
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Giardia lamblia	Kinase, NEK	0.0074	0.0531	1
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0074	0.0531	0.0531
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0732	0.0734
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0074	0.0531	0.9121
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.047	0.6898	0.7984
Brugia malayi	SH2 domain containing protein	0.0074	0.0531	0.0616
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0074	0.0531	0.0566
Schistosoma mansoni	hypothetical protein	0.0048	0.0108	0.0115
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0074	0.0531	0.0531
Schistosoma mansoni	hypothetical protein	0.0165	0.1991	0.2123
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Loa Loa (eye worm)	STE/STE20/SLK protein kinase	0.0161	0.1934	0.2148
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0074	0.0531	0.0531
Schistosoma mansoni	protein kinase	0.0161	0.1934	0.2063
Schistosoma mansoni	neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule	0.0048	0.0108	0.0115
Loa Loa (eye worm)	lethal protein 805	0.0165	0.1991	0.2214
Echinococcus multilocularis	leucine rich repeat containing protein 4	0.0048	0.0108	0.0108
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0074	0.0531	0.0531
Onchocerca volvulus		0.0074	0.0531	0.0375
Echinococcus granulosus	raf serine:threonine protein kinase	0.0074	0.0531	0.0531
Schistosoma mansoni	hypothetical protein	0.0076	0.0568	0.0606
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0074	0.0531	0.0616
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0074	0.0531	0.0531
Brugia malayi	basement membrane proteoglycan precursor	0.0048	0.0108	0.0125
Echinococcus multilocularis	heat shock protein 70	0.0074	0.0531	0.0531
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0048	0.0111	0.0129
Plasmodium falciparum	tyrosine kinase-like protein	0.0074	0.0531	0.66
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	hypothetical protein	0.0577	0.8612	1
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus multilocularis	Fibronectin, type III	0.0165	0.1991	0.1991
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	receptor type guanylyl cyclase	0.0074	0.0531	0.0531
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0074	0.0531	0.0531
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.0088	0.0763	1
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Schistosoma mansoni	serine/threonine protein kinase	0.0074	0.0531	0.0566
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0165	0.1991	0.1991
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0204	0.2615	0.2948
Schistosoma mansoni	septate junction protein	0.0048	0.0108	0.0115
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Entamoeba histolytica	hypothetical protein	0.0074	0.0534	0.9177
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2)	0.0058	0.0275	0.5
Echinococcus multilocularis	titin	0.0165	0.1991	0.1991
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0074	0.0531	0.0531
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0074	0.0531	0.0497
Brugia malayi	integrin-linked kinase	0.0074	0.0531	0.0616
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0074	0.0531	0.0531
Echinococcus multilocularis	activin receptor type	0.0075	0.0551	0.0551
Brugia malayi	Fibronectin type III domain containing protein	0.0165	0.1991	0.2312
Echinococcus granulosus	epidermal growth factor receptor	0.0074	0.0531	0.0531
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0074	0.0531	0.0616
Leishmania major	hypothetical protein, conserved	0.0165	0.1991	1
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0067	0.0428	0.0428
Echinococcus granulosus	peptidase Clp S14 family	0.0058	0.0275	0.0275
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Schistosoma mansoni	vesicular amine transporter	0.0412	0.5966	0.6363
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0052	0.0179	0.0208
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0074	0.0534	0.9177
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0074	0.0531	0.0494
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0074	0.0531	0.0497
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0074	0.0531	0.0616
Entamoeba histolytica	receptor protein kinase, putative	0.0074	0.0531	0.9121
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	SRC-1	0.0074	0.0531	0.0497
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Onchocerca volvulus		0.0204	0.2615	0.3082
Onchocerca volvulus		0.0074	0.0531	0.0375
Brugia malayi	Protein kinase domain containing protein	0.0161	0.1934	0.2246
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Echinococcus granulosus	peroxidasin	0.0087	0.0735	0.0735
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	SRC-1	0.0074	0.0531	0.0616
Echinococcus granulosus	defective proboscis extension response	0.0412	0.5966	0.5966
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0074	0.0531	0.0531
Onchocerca volvulus		0.0074	0.0531	0.0375
Giardia lamblia	Protein 21.1	0.0074	0.0531	1
Onchocerca volvulus		0.0165	0.1991	0.2271
Entamoeba histolytica	tyrosine kinase, putative	0.0074	0.0531	0.9121
Brugia malayi	Lethal protein 805	0.0165	0.1991	0.2312
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0074	0.0531	0.9121
Brugia malayi	Fibronectin type III domain containing protein	0.0165	0.1991	0.2312
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0074	0.0531	0.0616
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0074	0.0531	0.0531
Schistosoma mansoni	titin	0.0165	0.1991	0.2123
Schistosoma mansoni	septate junction protein	0.0086	0.0732	0.0781
Echinococcus multilocularis	transfer RNA-Thr	0.0074	0.0531	0.0531
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	UNCoordinated family member	0.0165	0.1991	0.2214
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0074	0.0531	0.0494
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0086	0.0732	0.085
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0735	0.0738
Entamoeba histolytica	protein kinase domain containing protein	0.0074	0.0531	0.9121
Loa Loa (eye worm)	TK/ABL protein kinase	0.0074	0.0531	0.0497
Brugia malayi	SPRY domain containing protein	0.0165	0.1991	0.2312
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	hypothetical protein	0.0165	0.1991	0.2214
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0165	0.1991	0.2214
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0074	0.0531	0.0531
Loa Loa (eye worm)	hypothetical protein	0.0086	0.0732	0.0734
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0531	0.0497
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0074	0.0531	0.0375
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0074	0.0531	0.0566
Echinococcus multilocularis	Immunoglobulin subtype	0.0048	0.0108	0.0108
Echinococcus granulosus	Immunoglobulin	0.0048	0.0108	0.0108
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Echinococcus granulosus	ephrin type A receptor 4 A	0.0074	0.0531	0.0531
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0048	0.0108	0.0115
Entamoeba histolytica	tyrosin kinase, putative	0.0074	0.0531	0.9121
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Trichomonas vaginalis	TKL family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0074	0.0531	0.0494
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0204	0.2615	0.3036
Trichomonas vaginalis	CAMK family protein kinase	0.0074	0.0531	0.0494
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Echinococcus granulosus	activin receptor type	0.0075	0.0551	0.0551
Echinococcus granulosus	Immunoglobulin subtype	0.0048	0.0108	0.0108
Schistosoma mansoni	protein kinase	0.0075	0.0551	0.0587
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0088	0.0763	0.5
Echinococcus multilocularis	pro neuregulin 2, membrane bound	0.0048	0.0108	0.0108
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0086	0.0732	0.0734
Schistosoma mansoni	tyrosine kinase	0.0074	0.0531	0.0566
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Loa Loa (eye worm)	TK/FER protein kinase	0.0074	0.0531	0.0497
Echinococcus granulosus	contactin	0.0251	0.3379	0.3379
Entamoeba histolytica	protein kinase, putative	0.0074	0.0531	0.9121
Schistosoma mansoni	serine/threonine protein kinase	0.0205	0.2635	0.281
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0074	0.0531	0.0531
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Onchocerca volvulus	Basement membrane proteoglycan homolog	0.0086	0.0732	0.0637
Onchocerca volvulus		0.0074	0.0531	0.0375
Loa Loa (eye worm)	hypothetical protein	0.0412	0.5966	0.6888
Echinococcus multilocularis	roundabout 2	0.0251	0.3379	0.3379
Schistosoma mansoni	protein tyrosine phosphatase	0.0165	0.1991	0.2123
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0074	0.0531	0.0531
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0074	0.0531	0.9121
Schistosoma mansoni	factor for adipocyte differentiation	0.0165	0.1991	0.2123
Brugia malayi	Protein kinase domain containing protein	0.0074	0.0531	0.0616
Loa Loa (eye worm)	hypothetical protein	0.0412	0.5966	0.6888
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0204	0.2615	0.2615
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0088	0.0763	1
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0165	0.1991	0.2123

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL2358803

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1749973