Detailed information for compound 1790797

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 353.392 | Formula: C19H15NO4S
  • H donors: 2 H acceptors: 4 LogP: 3.29 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1cc(c2c(c1/N=C/C=C/c1ccccc1)cccc2)S(=O)(=O)O
  • InChi: 1S/C19H15NO4S/c21-17-13-18(25(22,23)24)15-10-4-5-11-16(15)19(17)20-12-6-9-14-7-2-1-3-8-14/h1-13,21H,(H,22,23,24)/b9-6+,20-12+
  • InChiKey: LQDMBLDFPJKSTI-XCHVBMRISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0156 0.0479
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0013 0.0048 0.0048
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0226 0.2272
Loa Loa (eye worm) PXA domain-containing protein 0.0086 0.1126 0.1295
Loa Loa (eye worm) RGS-3 protein 0.0086 0.1126 0.1295
Schistosoma mansoni hypothetical protein 0.0015 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0156 0.0179
Loa Loa (eye worm) histone methyltransferase 0.001 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0156 0.0179
Brugia malayi nuclear receptor RXR 0.0011 0.0017 0.0036
Echinococcus multilocularis DCC interacting protein 13 beta 0.0013 0.0048 0.0048
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0013 0.0048 0.0055
Echinococcus multilocularis pleckstrin y domain containing family A 0.0013 0.0048 0.0048
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0013 0.0048 0.0048
Schistosoma mansoni dynamin 0.0013 0.0048 0.0048
Onchocerca volvulus 0.0013 0.0048 0.0147
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0015 0.0078 0.1226
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0017 0.0017
Brugia malayi Cytohesin 3 0.0013 0.0048 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0599 0.8694 0.8694
Echinococcus granulosus oxysterol binding protein 9 0.0013 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.1126 0.3367
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0086 0.0184
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0019
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0226 0.2272
Schistosoma mansoni serine/threonine protein kinase 0.0328 0.4691 0.4691
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0019
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0156 0.0479
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0156 0.0179
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0156 0.0156
Echinococcus granulosus serine/threonine protein kinase 0.0015 0.0078 0.0078
Toxoplasma gondii protein kinase domain-containing protein 0.0015 0.0078 0.0503
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) CWN-2 protein 0.0014 0.006 0.0069
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0422 0.0422
Leishmania major protein kinase, putative 0.0015 0.0078 0.0389
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0296 0.41
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0086 0.0086
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0831 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0156 0.0179
Echinococcus multilocularis expressed protein 0.0086 0.1126 0.1126
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0086 0.1126 0.1126
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0086 0.0184
Echinococcus granulosus dnaJ subfamily B 0.0396 0.5699 0.5699
Echinococcus granulosus Protein Wnt-11b 0.0014 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0296 0.4221 0.4854
Echinococcus granulosus regulator of G protein signaling 7 0.0086 0.1126 0.1126
Schistosoma mansoni axis inhibition protein axin 0.0086 0.1126 0.1126
Echinococcus granulosus GPCR family 2 0.0015 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.003 0.0296 0.034
Echinococcus granulosus Protein Wnt-04 0.0014 0.006 0.006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0156 0.0332
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Schistosoma mansoni regulator of G protein signaling 0.0086 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.0086 0.1126 0.1295
Loa Loa (eye worm) hypothetical protein 0.0025 0.0226 0.026
Schistosoma mansoni regulator of G protein signaling 0.0086 0.1126 0.1126
Schistosoma mansoni hypothetical protein 0.0013 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.002 0.0156 0.0179
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0296 0.0296
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0015 0.0078 0.0389
Plasmodium falciparum calcium-dependent protein kinase 7 0.0015 0.0078 0.171
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0242 0.3426 0.7303
Brugia malayi regulator of G-protein signaling rgs-7 0.0086 0.1126 0.2401
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Schistosoma mansoni rho gtpase activating protein 0.0013 0.0048 0.0048
Echinococcus multilocularis wingless type MMTV integration site family 0.0014 0.006 0.006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0156 0.0332
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0226 1
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Echinococcus granulosus pdz domain containing protein 0.0013 0.0048 0.0048
Schistosoma mansoni zinc finger protein 0.0013 0.0048 0.0048
Schistosoma mansoni regulator of G protein signaling 0.0086 0.1126 0.1126
Echinococcus multilocularis Pleckstrin y 0.0013 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.002 0.0156 0.0179
Schistosoma mansoni thyroid hormone receptor 0.002 0.0156 0.0156
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0025 0.0025
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Loa Loa (eye worm) zinc finger protein 0.0308 0.4405 0.5066
Echinococcus multilocularis axis inhibition protein axin 0.0086 0.1126 0.1126
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0242 0.3426 0.3426
Schistosoma mansoni hypothetical protein 0.0015 0.0086 0.0086
Schistosoma mansoni serine/threonine-protein kinase 0.0015 0.0078 0.0078
Echinococcus granulosus FTZ F1 alpha 0.002 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Onchocerca volvulus 0.0013 0.0048 0.0147
Echinococcus multilocularis beta 1 syntrophin 0.0013 0.0048 0.0048
Brugia malayi Pleckstrin Homology Domain 0.0013 0.0048 0.0102
Brugia malayi probable spectrin beta chain 0.0013 0.0048 0.0102
Brugia malayi hypothetical protein 0.0086 0.1126 0.2401
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0831 0.7262
Schistosoma mansoni hypothetical protein 0.0015 0.0086 0.0086
Echinococcus multilocularis regulator of G protein signaling 7 0.0086 0.1126 0.1126
Schistosoma mansoni hypothetical protein 0.0013 0.0048 0.0048
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0015 0.0078 0.0389
Echinococcus multilocularis muscleblind protein 1 0.0296 0.4221 0.4221
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0572 0.122
Loa Loa (eye worm) hypothetical protein 0.0296 0.4221 0.4854
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Schistosoma mansoni wnt related 0.0014 0.006 0.006
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0013 0.0048 0.0048
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0002 0.0004
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0015 0.0078 0.0389
Brugia malayi Pre-SET motif family protein 0.003 0.0296 0.0631
Echinococcus multilocularis beta adrenergic receptor kinase 0.0599 0.8694 0.8694
Schistosoma mansoni centaurin alpha 0.0013 0.0048 0.0048
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0599 0.8694 1
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.284 0.3267
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Brugia malayi MAX-1A 0.0013 0.0048 0.0102
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0013 0.0048 0.0048
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0086 0.1126 0.3367
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0013 0.0048 0.0147
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0347 0.074
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0013 0.0048 0.000000055717
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0296 0.0296
Brugia malayi PXA domain containing protein 0.0086 0.1126 0.2401
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0572 0.0658
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0086 0.1126 0.1126
Echinococcus granulosus beta 1 syntrophin 0.0013 0.0048 0.0048
Onchocerca volvulus 0.023 0.3251 1
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.1126 0.3367
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Brugia malayi nuclear receptor NHR-88 0.002 0.0156 0.0332
Brugia malayi Oxysterol binding protein 0.0013 0.0048 0.0102
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0013 0.0048 0.0048
Echinococcus multilocularis Pleckstrin y 0.0013 0.0048 0.0048
Echinococcus multilocularis regulator of G protein signaling 3 0.0086 0.1126 0.1126
Onchocerca volvulus 0.0013 0.0048 0.0147
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0017 0.0017
Brugia malayi hypothetical protein 0.0011 0.0017 0.0036
Schistosoma mansoni hypothetical protein 0.0011 0.0025 0.0025
Brugia malayi hypothetical protein 0.0016 0.0096 0.0206
Trypanosoma cruzi NIMA-related kinase, putative 0.0015 0.0078 0.0389
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0156 0.0332
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0013 0.0048 0.0048
Echinococcus multilocularis dynamin 1 0.0013 0.0048 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0086 0.0086
Echinococcus granulosus dynamin 1 0.0013 0.0048 0.0048
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0013 0.0048 0.0055
Schistosoma mansoni wnt related 0.0014 0.006 0.006
Brugia malayi Protein kinase domain containing protein 0.0015 0.0078 0.0167
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Echinococcus multilocularis zinc finger transcription factor gli2 0.0308 0.4405 0.4405
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0653 1
Brugia malayi hypothetical protein 0.0086 0.1126 0.2401
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0328 0.4691 0.5396
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0013 0.0048 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0017 0.0036
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0831 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0296 0.0296
Brugia malayi wnt family protein 0.0014 0.006 0.0129
Onchocerca volvulus 0.0013 0.0048 0.0147
Trypanosoma brucei protein kinase, putative 0.0015 0.0078 0.0389
Brugia malayi wnt family protein 0.0014 0.006 0.0129
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.0086 0.1126 0.1295
Echinococcus multilocularis Ras associated and pleckstrin y 0.0013 0.0048 0.0048
Echinococcus multilocularis microtubule associated protein 2 0.0688 1 1
Echinococcus granulosus regulator of G protein signaling 7 0.0086 0.1126 0.1126
Echinococcus granulosus Oxysterol binding protein 11 0.0013 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0013 0.0048 0.0048
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0156 0.0156
Echinococcus multilocularis myotubularin protein 13 0.0013 0.0048 0.0048
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0156 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0328 0.4691 1
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0013 0.0048 0.0048
Leishmania major folate/biopterin transporter, putative 0.0015 0.0078 0.0389
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0013 0.0048 0.0048
Echinococcus granulosus regulator of G protein signaling 3 0.0086 0.1126 0.1126
Echinococcus multilocularis regulator of G protein signaling 3 0.0086 0.1126 0.1126
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0514 0.7429 0.7429
Brugia malayi Zinc finger, C2H2 type family protein 0.0308 0.4405 0.939
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0086 0.1126 0.1126
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0156 0.0156
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0296 0.0296
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0156 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.1126 0.3367
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0015 0.0078 0.0389
Entamoeba histolytica PH domain containing protein kinase, putative 0.0015 0.0078 0.0282
Loa Loa (eye worm) syntrophin-1 0.0013 0.0048 0.0055
Loa Loa (eye worm) hypothetical protein 0.002 0.0156 0.0179
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0015 0.0078 0.0389
Brugia malayi hypothetical protein 0.012 0.1633 0.3482
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0831 1
Echinococcus multilocularis actin binding protein anillin 0.0013 0.0048 0.0048
Onchocerca volvulus 0.0028 0.0271 0.0833
Echinococcus multilocularis WNT 0.0014 0.006 0.006
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0156 0.0479
Entamoeba histolytica protein kinase, putative 0.0015 0.0078 0.0282
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0013 0.0048 0.0055
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0013 0.0048 0.0048
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0572 0.122
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0003 0.0003
Schistosoma mansoni thyroid hormone receptor 0.002 0.0156 0.0156
Entamoeba histolytica hypothetical protein 0.0086 0.1126 1
Echinococcus granulosus regulator of G protein signaling 3 0.0086 0.1126 0.1126
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0156 0.0156
Entamoeba histolytica protein kinase, putative 0.0015 0.0078 0.0282
Brugia malayi Regulator of G protein signaling domain containing protein 0.0086 0.1126 0.2401
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0156 0.0332
Entamoeba histolytica protein kinase, putative 0.0015 0.0078 0.0282
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0013 0.0048 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0296 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0156 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Entamoeba histolytica p21-activated kinase 0.0015 0.0078 0.0282
Brugia malayi Variant SH3 domain containing protein 0.0013 0.0048 0.0102
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0156 0.0156
Echinococcus granulosus G protein coupled receptor kinase 1 0.0514 0.7429 0.7429
Brugia malayi nuclear hormone receptor 0.002 0.0156 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0242 0.3426 0.394
Entamoeba histolytica PH domain containing protein kinase, putative 0.0015 0.0078 0.0282
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0025 0.0025
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0013 0.0048 0.0048
Schistosoma mansoni microtubule-associated protein tau 0.0688 1 1
Echinococcus granulosus Regulator of G protein signaling 20 0.0086 0.1126 0.1126
Loa Loa (eye worm) uncoordinated protein 104 0.0013 0.0048 0.0055
Trichomonas vaginalis centaurin gamma, putative 0.0013 0.0048 0.000000055717
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0156 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.1126 0.3367
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.0048 0.0572 0.0658
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Echinococcus multilocularis muscleblind protein 0.0296 0.4221 0.4221
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Brugia malayi hypothetical protein 0.0025 0.0226 0.0481
Onchocerca volvulus 0.0013 0.0048 0.0147
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0086 0.0086
Echinococcus multilocularis cytohesin 1 0.0013 0.0048 0.0048
Onchocerca volvulus Protein melted homolog 0.0013 0.0048 0.0147
Entamoeba histolytica protein kinase, putative 0.0015 0.0078 0.0282
Echinococcus multilocularis oxysterol binding protein 1 0.0013 0.0048 0.0048
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0013 0.0048 0.0147
Echinococcus granulosus Pleckstrin y 0.0013 0.0048 0.0048
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0831 0.1771
Schistosoma mansoni regulator of G protein signaling 0.0086 0.1126 0.1126
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0156 0.0156
Echinococcus granulosus GRB2 associated binding protein 3 0.0013 0.0048 0.0048
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0296 0.0296
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Brugia malayi Wnt-2 protein precursor 0.0014 0.006 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0156 0.0179
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0156 0.0156
Schistosoma mansoni hypothetical protein 0.0013 0.0048 0.0048
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0015 0.0078 0.0389
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0242 0.3426 0.3426
Schistosoma mansoni myotubularin-related protein 0.0013 0.0048 0.0048
Trichomonas vaginalis set domain proteins, putative 0.023 0.3251 1
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Loa Loa (eye worm) hypothetical protein 0.002 0.0156 0.0179
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0156 0.0179
Schistosoma mansoni nuclear hormone receptor 0.002 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0156 0.0156
Schistosoma mansoni wnt related 0.0014 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0033 0.0347 0.0347
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Loa Loa (eye worm) wnt-4 protein 0.0014 0.006 0.0069
Echinococcus granulosus oxysterol binding protein 1 0.0013 0.0048 0.0048
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0156 0.0332
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0015 0.0078 0.0389
Trypanosoma brucei rac serine-threonine kinase, putative 0.0015 0.0078 0.0389
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0017 0.0017
Onchocerca volvulus 0.0013 0.0048 0.0147
Leishmania major serine/threonine-protein kinase a, putative 0.0015 0.0078 0.0389
Loa Loa (eye worm) hypothetical protein 0.0015 0.0086 0.0099
Echinococcus granulosus DCC interacting protein 13 beta 0.0013 0.0048 0.0048
Trichomonas vaginalis centaurin/arf, putative 0.0013 0.0048 0.000000055717
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0156 0.0156
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0015 0.0078 0.0389
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0156 0.0332
Schistosoma mansoni wnt related 0.0014 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0013 0.0048 0.0048
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0156 0.0156
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0013 0.0048 0.000000055717
Echinococcus granulosus Protein Wnt-111 0.0014 0.006 0.006
Entamoeba histolytica protein kinase, putative 0.0015 0.0078 0.0282
Echinococcus granulosus calcium dependent secretion activator 1 0.0013 0.0048 0.0048
Loa Loa (eye worm) cytohesin 3 0.0013 0.0048 0.0055
Brugia malayi Uncoordinated protein 104 0.0013 0.0048 0.0102
Echinococcus granulosus axis inhibition protein axin 0.0086 0.1126 0.1126
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0013 0.0048 0.0102
Plasmodium vivax SET domain protein, putative 0.003 0.0296 1
Echinococcus multilocularis oxysterol binding protein 9 0.0013 0.0048 0.0048
Onchocerca volvulus Huntingtin homolog 0.012 0.1633 0.5025
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0086 0.1126 0.1295
Onchocerca volvulus 0.003 0.0296 0.0911
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0831 0.0831
Onchocerca volvulus Huntingtin homolog 0.012 0.1633 0.5025
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.0033 0.0347 0.04
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0013 0.0048 0.0048
Echinococcus multilocularis pdz domain containing protein 0.0013 0.0048 0.0048
Entamoeba histolytica hypothetical protein 0.0086 0.1126 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Entamoeba histolytica PH domain containing protein kinase, putative 0.0015 0.0078 0.0282
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0015 0.0078 0.0389
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0015 0.0078 0.0389
Entamoeba histolytica PH domain containing protein kinase, putative 0.0015 0.0078 0.0282
Echinococcus multilocularis protein Wnt 2 0.0014 0.006 0.006
Schistosoma mansoni goodpasture antigen-binding protein 0.0013 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0086 0.1126 0.1295
Trypanosoma cruzi NIMA-related kinase, putative 0.0015 0.0078 0.0389
Schistosoma mansoni dynamin 0.0013 0.0048 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.1126 0.3367
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0226 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0156 0.0179
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.0086 0.1126 0.1295
Echinococcus granulosus Pleckstrin y 0.0013 0.0048 0.0048
Onchocerca volvulus 0.0013 0.0048 0.0147
Echinococcus granulosus expressed protein 0.0086 0.1126 0.1126
Brugia malayi Dynamin 0.0013 0.0048 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0156 0.0332
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0015 0.0078 0.0095
Loa Loa (eye worm) AGC/AKT protein kinase 0.0015 0.0078 0.009
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0226 0.2939
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0013 0.0048 0.0048
Schistosoma mansoni regulator of G protein signaling 0.0086 0.1126 0.1126
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0015 0.0078 0.0389
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0156 0.0156
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0015 0.0078 0.0503
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0015 0.0078 0.0389
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0242 0.3426 0.394
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0086 0.1126 0.1126
Schistosoma mansoni oxysterol-binding protein 1 0.0013 0.0048 0.0048
Brugia malayi CXXC zinc finger family protein 0.0028 0.0271 0.0577
Schistosoma mansoni zinc finger protein 0.0013 0.0048 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Echinococcus granulosus zinc finger transcription factor gli2 0.0308 0.4405 0.4405
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0017 0.0019
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0156 0.0156
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0746 0.0746
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0156 0.0156
Schistosoma mansoni oxysterol-binding protein 1 0.0013 0.0048 0.0048
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0226 0.2272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0156 0.0179
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0156 0.0179
Brugia malayi Wnt-4 protein precursor 0.0014 0.006 0.0129
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Echinococcus multilocularis Oxysterol binding protein 11 0.0013 0.0048 0.0048
Entamoeba histolytica PH domain containing protein kinase, putative 0.0015 0.0078 0.0282
Schistosoma mansoni wnt-5 0.0014 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.012 0.1633 0.1879
Leishmania major protein kinase, putative 0.0015 0.0078 0.0389
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0013 0.0048 0.0048
Schistosoma mansoni hypothetical protein 0.0013 0.0048 0.0048
Echinococcus multilocularis WNT 0.0014 0.006 0.006
Echinococcus multilocularis cpg binding protein 0.0029 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.5699 0.5699
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0013 0.0048 0.0048
Echinococcus multilocularis GPCR, family 2 0.0015 0.0086 0.0086
Echinococcus multilocularis calcium dependent secretion activator 1 0.0013 0.0048 0.0048
Trypanosoma cruzi Protein kinase B 0.0015 0.0078 0.0389
Schistosoma mansoni goodpasture antigen-binding protein 0.0013 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0019
Echinococcus granulosus cytohesin 1 0.0013 0.0048 0.0048
Onchocerca volvulus 0.002 0.0156 0.0479
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0017 0.0017
Brugia malayi Variant SH3 domain containing protein 0.0013 0.0048 0.0102
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0226 0.7167
Schistosoma mansoni hypothetical protein 0.0396 0.5699 0.5699
Loa Loa (eye worm) hypothetical protein 0.0014 0.006 0.0069
Echinococcus granulosus Pleckstrin y 0.0013 0.0048 0.0048
Echinococcus multilocularis regulator of G protein signaling 0.0086 0.1126 0.1126
Brugia malayi A-kinase anchor protein 10, precursor 0.0086 0.1126 0.2401
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0156 0.0332
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0013 0.0048 0.0048
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0013 0.0048 0.0048
Echinococcus granulosus myotubularin protein 13 0.0013 0.0048 0.0048
Onchocerca volvulus Putative zinc finger protein 0.0013 0.0048 0.0147
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0013 0.0048 0.0048
Echinococcus granulosus Protein Wnt-5 0.0014 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Brugia malayi Syntrophin-1 0.0013 0.0048 0.0102
Brugia malayi TBC domain containing protein 0.0013 0.0048 0.0102
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0013 0.0048 0.000000055717
Echinococcus granulosus axis inhibition protein axin 0.0086 0.1126 0.1126
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0013 0.0048 0.0102
Echinococcus multilocularis axis inhibition protein axin 0.0086 0.1126 0.1126
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0156 0.0332
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Echinococcus multilocularis protein Wnt 1 0.0014 0.006 0.006
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Echinococcus multilocularis rac serine:threonine kinase 0.0015 0.0078 0.0078
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) hypothetical protein 0.012 0.1633 0.1879
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0086 0.1126 0.1295
Brugia malayi PXA domain containing protein 0.0086 0.1126 0.2401
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Echinococcus granulosus beta-adrenergic receptor kinase 0.0599 0.8694 0.8694
Brugia malayi ecdysteroid receptor 0.002 0.0156 0.0332
Brugia malayi Pre-SET motif family protein 0.0202 0.284 0.6055
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Loa Loa (eye worm) hypothetical protein 0.0086 0.1126 0.1295
Brugia malayi Regulator of G protein signaling domain containing protein 0.0086 0.1126 0.2401
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0156 0.0156
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0422 0.0422
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0831 1
Entamoeba histolytica protein kinase, putative 0.0015 0.0078 0.0282
Brugia malayi Dynamin 0.0013 0.0048 0.0102
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0271 0.0271
Entamoeba histolytica ARF GTPase activating protein, putative 0.0013 0.0048 0.00000016549
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0003 0.0003
Schistosoma mansoni cpg binding protein 0.0029 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Loa Loa (eye worm) hypothetical protein 0.002 0.0156 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.1126 0.3367
Echinococcus multilocularis Regulator of G protein signaling 20 0.0086 0.1126 0.1126
Schistosoma mansoni serine/threonine-protein kinase 0.0015 0.0078 0.0078
Brugia malayi PH domain containing protein 0.0013 0.0048 0.0102
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0156 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0156 0.0332
Echinococcus multilocularis regulator of G protein signaling 7 0.0086 0.1126 0.1126
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0015 0.0078 0.0095
Schistosoma mansoni growth factor receptor-bound protein 0.0013 0.0048 0.0048
Echinococcus multilocularis wnt family member wnt11 2 0.0014 0.006 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0599 0.8694 0.8694
Brugia malayi wnt family protein 0.0014 0.006 0.0129
Loa Loa (eye worm) hypothetical protein 0.002 0.0156 0.0179
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0015 0.0078 0.0389
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0156 0.0156
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0831 0.0831
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0013 0.0048 0.000000055717
Schistosoma mansoni vav2 0.0013 0.0048 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0156 0.0332
Echinococcus multilocularis Pleckstrin y 0.0013 0.0048 0.0048
Onchocerca volvulus outspread protein homolog 0.0013 0.0048 0.0147
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.002 0.0156 0.0179
Loa Loa (eye worm) Wnt2 protein 0.0014 0.006 0.0069
Echinococcus granulosus oxysterol binding protein 3 0.0013 0.0048 0.0048
Echinococcus granulosus muscleblind protein 0.0296 0.4221 0.4221
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Echinococcus multilocularis GRB2 associated binding protein 3 0.0013 0.0048 0.0048
Echinococcus multilocularis oxysterol binding protein 3 0.0013 0.0048 0.0048
Echinococcus granulosus Rho GTPase activating protein 24 0.0013 0.0048 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0017 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0156 0.0156
Brugia malayi Cadps2 protein 0.0013 0.0048 0.0102
Loa Loa (eye worm) rho-GTPase-activating 0.0013 0.0048 0.0055
Brugia malayi Plekhf2 protein 0.0013 0.0048 0.0102
Loa Loa (eye worm) hypothetical protein 0.0013 0.0048 0.0055
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Schistosoma mansoni z-protein (S1r protein) 0.0086 0.1126 0.1126
Leishmania major hypothetical protein, conserved 0.0025 0.0226 0.2272
Loa Loa (eye worm) Plekhf2 protein 0.0013 0.0048 0.0055
Entamoeba histolytica protein kinase, putative 0.0015 0.0078 0.0282
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0156 0.0332
Entamoeba histolytica hypothetical protein 0.0015 0.0078 0.0282
Echinococcus granulosus protein Wnt 1 0.0014 0.006 0.006
Entamoeba histolytica PH domain containing protein kinase, putative 0.0015 0.0078 0.0282
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0086 0.1126 0.1126
Loa Loa (eye worm) oxysterol binding protein 0.0013 0.0048 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0156 0.0156
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0013 0.0048 0.0055
Brugia malayi Muscleblind-like protein 0.0296 0.4221 0.8997
Echinococcus granulosus pleckstrin y domain containing family A 0.0013 0.0048 0.0048
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0019
Brugia malayi wnt family protein 0.0014 0.006 0.0129
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0013 0.0048 0.0102
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0015 0.0078 0.0389
Brugia malayi steroid hormone receptor 0.002 0.0156 0.0332
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0831 0.0956
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0015 0.0078 0.0389
Schistosoma mansoni axis inhibition protein axin 0.0086 0.1126 0.1126
Entamoeba histolytica hypothetical protein 0.0086 0.1126 1
Echinococcus granulosus protein Wnt 2 0.0014 0.006 0.006
Schistosoma mansoni syntrophin 0.0013 0.0048 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Schistosoma mansoni hypothetical protein 0.0015 0.0086 0.0086
Schistosoma mansoni cpg binding protein 0.0028 0.0271 0.0271
Brugia malayi Oxysterol-binding protein 0.0013 0.0048 0.0102
Brugia malayi regulator of G-protein signaling egl-10 0.0086 0.1126 0.2401
Schistosoma mansoni coup transcription factor 0.002 0.0156 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0156 0.0332
Schistosoma mansoni cpg binding protein 0.0029 0.0294 0.0294
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0156 0.0156
Echinococcus multilocularis Rho GTPase activating protein 24 0.0013 0.0048 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0296 0.0296
Brugia malayi hypothetical protein 0.0013 0.0048 0.0102
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0156 0.0156
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0831 0.0831
Echinococcus granulosus cpg binding protein 0.0029 0.0294 0.0294
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0086 0.0099
Brugia malayi hypothetical protein 0.0011 0.0017 0.0036
Entamoeba histolytica hypothetical protein 0.0015 0.0078 0.0282
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0078 0.0095
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0271 0.0312
Loa Loa (eye worm) PH domain-containing protein 0.0013 0.0048 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0156 0.0332

Activities

Activity type Activity value Assay description Source Reference
-logMIC (functional) = 1.45 Antibacterial activity against Escherichia coli MTCC 1652 after 24 hr by tube dilution method ChEMBL. No reference
-logMIC (functional) = 1.45 Antifungal activity against Candida albicans MTCC 227 after 48 hr by tube dilution method ChEMBL. No reference
MBC (functional) > 0.14 uM/ml Bactericidal activity against Escherichia coli MTCC 1652 ChEMBL. No reference
MFC (functional) > 0.14 uM/ml Fungicidal activity against Candida albicans MTCC 227 ChEMBL. No reference
Ratio (functional) = 3 Ratio of MFC to MIC for Candida albicans MTCC 227 ChEMBL. No reference
Ratio (functional) = 3 Ratio of MBC to MIC for Escherichia coli MTCC 1652 ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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