Detailed information for compound 1800247

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 418.614 | Formula: C22H43O3PS
  • H donors: 0 H acceptors: 0 LogP: 8.92 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOP(=S)(OCCC(CCC=C(C)C)C)OCCC(CCC=C(C)C)C
  • InChi: 1S/C22H43O3PS/c1-8-23-26(27,24-17-15-21(6)13-9-11-19(2)3)25-18-16-22(7)14-10-12-20(4)5/h11-12,21-22H,8-10,13-18H2,1-7H3
  • InChiKey: WZQRGRRDGCAVIJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0067 0.4727
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0027 0.0026
Brugia malayi N-terminal motif family protein 0.0192 0.0565 0.5968
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.012 0.0343 0.3487
Brugia malayi hypothetical protein 0.0039 0.0089 0.0936
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0035 0.0077 0.5405
Plasmodium vivax vivapain-2 0.0015 0.0016 0.1175
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0001 0.009
Onchocerca volvulus 0.0015 0.0016 0.0016
Echinococcus multilocularis JmjC domain containing protein 4 0.001 0.0001 0.0001
Trypanosoma brucei glycerolphosphate mutase, putative 0.0054 0.0139 0.0139
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0037 0.0084 0.0083
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.007 0.5075
Echinococcus multilocularis musashi 0.0029 0.006 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0666 0.2039 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0027 0.0027
Echinococcus multilocularis high affinity choline transporter 1 0.0314 0.0946 0.0946
Brugia malayi Cathepsin L-like precursor 0.0015 0.0016 0.0165
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0095 0.0463
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0046
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0007 0.0486
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0018 0.0017
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0035 0.0077 0.0077
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0314 0.0946 0.0946
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0102 0.0287 0.0287
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0027 0.0026
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0666 0.2039 0.3463
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0027 0.0027
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0067 0.4859
Onchocerca volvulus 0.0019 0.0027 0.0026
Echinococcus granulosus cathepsin l1 0.001 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.001 0.0001 0.0002
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0001
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0027 0.0026
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.0054 0.0139 0.1392
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.0047 0.0047
Onchocerca volvulus Protein UBASH3A homolog 0.0054 0.0139 0.0138
Leishmania major hypothetical protein, conserved 0.0054 0.0139 0.0139
Schistosoma mansoni rab6-interacting 0.0039 0.0089 0.0089
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0089 0.0088
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0054 0.0139 0.0139
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0016 0.0027
Plasmodium vivax thioredoxin reductase, putative 0.0044 0.0106 0.7661
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Schistosoma mansoni inositol transporter 0.0035 0.0077 0.0077
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0067 0.0067
Mycobacterium ulcerans phosphohistidine phosphatase SixA 0.0054 0.0139 0.0235
Echinococcus granulosus sodium:myo inositol cotransporter 0.0035 0.0077 0.0077
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0035 0.0077 0.0077
Brugia malayi Papain family cysteine protease containing protein 0.0015 0.0016 0.0165
Echinococcus multilocularis solute carrier family 5 0.0035 0.0077 0.0077
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.007 0.5075
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.3173 0.9831 0.9831
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0011 0.0002 0.0171
Trypanosoma cruzi trypanothione reductase, putative 0.0044 0.0106 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0027 0.0027
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.007 0.0265
Onchocerca volvulus 0.0015 0.0016 0.0016
Loa Loa (eye worm) fibroinase 0.0015 0.0016 0.0016
Onchocerca volvulus 0.3228 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0078 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0149 0.0149
Mycobacterium ulcerans acid phosphatase 0.0054 0.0139 0.0235
Trichomonas vaginalis aldo/keto reductase, putative 0.0037 0.0084 0.0407
Onchocerca volvulus 0.0029 0.006 0.0059
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0089 0.0089
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0095 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0127 0.0617
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0027 0.0277
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0054 0.0139 0.0139
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0089 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0027 0.0277
Schistosoma mansoni hypothetical protein 0.0054 0.0139 0.0139
Leishmania major phosphoglycerate mutase protein, putative 0.0054 0.0139 0.0139
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0093 0.0093
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0033 0.007 0.0119
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0015 0.0017 0.0017
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0016 0.0075
Chlamydia trachomatis protoporphyrinogen oxidase 0.0025 0.0047 0.2481
Leishmania major prostaglandin f synthase, putative 0.0037 0.0084 0.0084
Loa Loa (eye worm) histone methyltransferase 0.001 0.0001 0.0000073245
Schistosoma mansoni phd/f-box containing protein 0.001 0.0001 0.0001
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.012 0.0343 0.0343
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0001 0.0001
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.3173 0.9831 0.9831
Schistosoma mansoni lipoxygenase 0.0231 0.0687 0.0687
Mycobacterium ulcerans oxidoreductase 0.0025 0.0047 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0287 0.1405
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0095 0.0997
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0035 0.2501
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0027 0.0277
Trichomonas vaginalis aldo/keto reductase, putative 0.0037 0.0084 0.0407
Schistosoma mansoni hypothetical protein 0.0033 0.007 0.007
Schistosoma mansoni high-affinity choline transporter 0.0314 0.0946 0.0946
Brugia malayi Cathepsin L-like precursor 0.0015 0.0016 0.0165
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0054 0.0139 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0287 0.1405
Echinococcus multilocularis cathepsin L cysteine protease 0.0015 0.0016 0.0016
Schistosoma mansoni jumonji domain containing protein 0.001 0.0001 0.0001
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0037 0.0084 0.0877
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0077
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0027 0.0027
Schistosoma mansoni alpha glucosidase 0.004 0.0095 0.0095
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0586 0.0586
Trypanosoma brucei phosphoglycerate mutase, putative 0.0054 0.0139 0.0139
Mycobacterium ulcerans lipoprotein LpqD 0.0054 0.0139 0.0235
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Echinococcus granulosus thioredoxin glutathione reductase 0.0045 0.0108 0.0108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Echinococcus multilocularis phosphoglycerate mutase 0.0054 0.0139 0.0139
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0054 0.0139 0.0139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0078 0.0078
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0586 0.0586
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0343 0.1681
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0072 0.0072
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0054 0.0139 0.0139
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0035 0.0035
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0112 0.0316 0.3211
Schistosoma mansoni protein phosphatase 2C 0.001 0.0001 0.0001
Schistosoma mansoni cathepsin F (C01 family) 0.0015 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0027 0.0277
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0198 0.0586 0.0586
Loa Loa (eye worm) phosphofructokinase 0.012 0.0343 0.0343
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.1242 0.1242
Echinococcus multilocularis geminin 0.0764 0.2345 0.2345
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0015 0.0016 0.0016
Echinococcus multilocularis lysine specific demethylase 6a 0.001 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0139 0.0676
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.1377 0.4249 0.4249
Echinococcus multilocularis aldo keto reductase 0.0037 0.0084 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.0287 0.0287
Entamoeba histolytica aldose reductase, putative 0.0037 0.0084 0.0142
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.007 0.4401
Schistosoma mansoni hypothetical protein 0.0032 0.0067 0.0067
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.1905 0.5889 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0033 0.007 0.007
Mycobacterium tuberculosis Probable reductase 0.0101 0.0282 0.2855
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0035 0.0166
Echinococcus granulosus phosphoglycerate mutase 0.0054 0.0139 0.0139
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0015 0.0017 0.1203
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0089 0.0089
Echinococcus multilocularis peregrin 0.0032 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0011 0.0002 0.0017
Leishmania major cathepsin L-like protease 0.0058 0.0149 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0015 0.0016 0.0076
Mycobacterium ulcerans 6-phosphofructokinase 0.012 0.0343 0.0583
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0095 0.0463
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0027 0.0027
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0142 1
Plasmodium falciparum phd finger protein, putative 0.0032 0.0067 0.4859
Trypanosoma brucei polo-like protein kinase 0.0102 0.0287 0.0287
Echinococcus multilocularis cathepsin L cysteine protease 0.0015 0.0016 0.0016
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0054 0.0139 0.0139
Echinococcus granulosus dnaJ subfamily B 0.0409 0.1242 0.1242
Plasmodium falciparum phosphoglycerate mutase, putative 0.0054 0.0139 1
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0027 0.0052 0.3676
Onchocerca volvulus 0.0029 0.0059 0.0058
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0054 0.0139 0.0139
Mycobacterium tuberculosis Probable oxidoreductase 0.0112 0.0316 0.3211
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0666 0.2039 1
Onchocerca volvulus 0.0015 0.0016 0.0016
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0015 0.0016 0.1175
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.012 0.0343 0.3487
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0095 0.0095
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Onchocerca volvulus Protein UBASH3A homolog 0.0054 0.0139 0.0138
Brugia malayi Pre-SET motif family protein 0.0035 0.0078 0.0819
Echinococcus granulosus phosphoglycerate mutase 0.0054 0.0139 0.0139
Onchocerca volvulus 0.0015 0.0016 0.0016
Mycobacterium tuberculosis Probable oxidoreductase 0.0037 0.0084 0.0831
Schistosoma mansoni alpha-glucosidase 0.0157 0.0457 0.0457
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0026
Leishmania major hypothetical protein, conserved 0.001 0.0001 0.0001
Toxoplasma gondii histone lysine demethylase JMJD6a 0.001 0.0001 0.0062
Echinococcus granulosus 6 phosphofructokinase 0.012 0.0343 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0095 0.0095
Mycobacterium ulcerans hypothetical protein 0.1905 0.5889 1
Schistosoma mansoni hypothetical protein 0.0054 0.0139 0.0139
Leishmania major hypothetical protein, conserved 0.0054 0.0139 0.0139
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0106 0.0106
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.3228 1 1
Leishmania major cathepsin L-like protease 0.0015 0.0016 0.0016
Mycobacterium tuberculosis Possible oxidoreductase 0.0025 0.0047 0.0455
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0192 0.0565 0.0564
Trichomonas vaginalis aldo-keto reductase, putative 0.0011 0.0002 0.0008
Trichomonas vaginalis glutaminase, putative 0.0306 0.092 0.4511
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.0536 0.0536
Loa Loa (eye worm) ctsf protein 0.0015 0.0016 0.0016
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0054 0.0139 0.0139
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0011 0.0002 0.0008
Mycobacterium ulcerans phosphoglyceromutase 0.0054 0.0139 0.0235
Loa Loa (eye worm) cysteine protease 0.0015 0.0016 0.0016
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Echinococcus multilocularis thioredoxin glutathione reductase 0.0045 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0054 0.0139 0.0138
Leishmania major phosphoglycerate mutase, putative 0.0054 0.0139 0.0139
Echinococcus multilocularis phosphoglycerate mutase 0.0054 0.0139 0.0139
Echinococcus granulosus sodium:glucose cotransporter 0.0035 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Echinococcus granulosus voltage gated potassium channel subunit 0.0011 0.0002 0.0002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.001 0.0001 0.0001
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0027 0.0277
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.0054 0.0139 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0102 0.0287 0.0287
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0095 0.0161
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0067 0.0067
Brugia malayi hypothetical protein 0.0033 0.007 0.0736
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0027 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0586 0.0586
Loa Loa (eye worm) oxidoreductase 0.0037 0.0084 0.0083
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0054 0.0139 0.0139
Toxoplasma gondii NADPH-glutathione reductase 0.0015 0.0017 0.1171
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.0717 0.0716
Schistosoma mansoni intermediate filament proteins 0.0029 0.006 0.006
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0343 0.0583
Schistosoma mansoni pol-related 0.0037 0.0084 0.0084
Schistosoma mansoni coup transcription factor 0.0019 0.0027 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0343 0.1681
Echinococcus granulosus cathepsin l1 0.0015 0.0016 0.0016
Mycobacterium tuberculosis Possible hydrolase MutT1 0.0054 0.0139 0.1392
Onchocerca volvulus Cathepsin L homolog 0.0015 0.0016 0.0016
Plasmodium falciparum thioredoxin reductase 0.0015 0.0017 0.1203
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0027 0.0277
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.3173 0.9831 0.9831
Echinococcus granulosus phd:f box containing protein 0.001 0.0001 0.0001
Echinococcus granulosus peregrin 0.0032 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Giardia lamblia Fructose-bisphosphate aldolase 0.0666 0.2039 0.3444
Onchocerca volvulus Alhambra homolog 0.0032 0.0067 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0127 0.0617
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0054 0.0139 0.0676
Trypanosoma brucei glucosidase, putative 0.004 0.0095 0.0095
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.007 0.4937
Echinococcus granulosus aldehyde reductase 0.0026 0.0051 0.0051
Onchocerca volvulus 0.0037 0.0084 0.0083
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.001 0.0001 0.0001
Schistosoma mansoni lamin 0.0029 0.006 0.006
Plasmodium vivax aldehyde reductase, putative 0.0011 0.0002 0.0171
Echinococcus granulosus solute carrier family 5 0.0035 0.0077 0.0077
Mycobacterium leprae Possible phosphoglycerate mutase 0.0054 0.0139 0.1392
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.007 0.5075
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0341
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0033 0.0336
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0343 0.1681
Onchocerca volvulus 0.0037 0.0084 0.0083
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0016 0.0016
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0027 0.0027
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0089 0.0089
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0011 0.0002 0.0002
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0027 0.0027
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0078 0.0078
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.0054 0.0139 0.1392
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0054 0.0139 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0027 0.0026
Brugia malayi hypothetical protein 0.0025 0.0047 0.0488
Loa Loa (eye worm) intermediate filament protein 0.0029 0.006 0.0059
Loa Loa (eye worm) hypothetical protein 0.0039 0.0089 0.0088
Schistosoma mansoni loxhd1 0.0039 0.0089 0.0089
Leishmania major cathepsin L-like protease 0.0015 0.0016 0.0016
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0054 0.0139 0.0139
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0001
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0089 0.6436
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0095 0.0095
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0025 0.0047 0.3386
Mycobacterium ulcerans glutaminase 0.0306 0.092 0.1563
Schistosoma mansoni alpha-glucosidase 0.0157 0.0457 0.0457
Echinococcus granulosus high affinity choline transporter 1 0.0314 0.0946 0.0946
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0016 0.0162
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0044 0.0106 0.1061
Mycobacterium leprae conserved hypothetical protein 0.0054 0.0139 0.1392
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0325 0.098 0.1665
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0015 0.0017 0.0017
Leishmania major glycerolphosphate mutase, putative 0.0054 0.0139 0.0139
Onchocerca volvulus 0.0011 0.0002 0.0002
Onchocerca volvulus 0.0037 0.0084 0.0083
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0037 0.0084 0.0831
Echinococcus granulosus cathepsin l cysteine peptidase 0.0015 0.0016 0.0016
Treponema pallidum fructose-bisphosphate aldolase 0.0666 0.2039 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0015 0.0017 0.0146
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0046
Brugia malayi 6-phosphofructokinase 0.012 0.0343 0.3625
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0054 0.0139 0.0139
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0047 0.3386
Mycobacterium ulcerans hypothetical protein 0.0054 0.0139 0.0235
Onchocerca volvulus 0.0035 0.0078 0.0077
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0053 0.0133 0.0133
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0054 0.0139 0.0139
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0035 0.0166
Entamoeba histolytica alcohol dehydrogenase, putative 0.0011 0.0002 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0093 0.0092
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0078 0.5488
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0035 0.2501
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0006 0.0006
Brugia malayi AF-10 protein 0.001 0.0001 0.0006
Onchocerca volvulus 0.0054 0.0139 0.0138
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0088 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Mycobacterium ulcerans oxidoreductase 0.0037 0.0084 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0027 0.0277
Trichomonas vaginalis glutathione reductase, putative 0.0015 0.0017 0.0078
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0198 0.0586 0.0585
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0027 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0149 0.0149
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0015 0.0017 0.0017
Echinococcus granulosus sodium:glucose cotransporter 2 0.0035 0.0077 0.0077
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0035 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0025 0.0047 0.0047
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0015 0.0017 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0016 0.0075
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0102 0.0287 0.0286
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0037 0.0084 0.0877
Schistosoma mansoni 6-phosphofructokinase 0.3228 1 1
Brugia malayi jmjC domain containing protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0026
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0035 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Brugia malayi phosphoglycerate mutase family protein 0.0054 0.0139 0.1458
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Entamoeba histolytica hypothetical protein 0.0033 0.007 0.0119
Trypanosoma brucei aldo/keto reductase, putative 0.0011 0.0002 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0172 0.0171
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Toxoplasma gondii phosphoglycerate mutase family protein 0.0054 0.0139 0.9729
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0027 0.0277
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0045 0.0108 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Toxoplasma gondii phosphoglycerate mutase PGMII 0.0054 0.0139 0.9729
Echinococcus granulosus phosphoglycerate mutase 0.0054 0.0139 0.0139
Brugia malayi CXXC zinc finger family protein 0.0029 0.0059 0.0612
Toxoplasma gondii exonuclease III APE 0.0021 0.0035 0.2433
Trypanosoma cruzi aldo-keto reductase 0.0037 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.0076
Schistosoma mansoni cathepsin F (C01 family) 0.0015 0.0016 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0054 0.0137 0.0137
Echinococcus granulosus lamin 0.0029 0.006 0.006
Trypanosoma cruzi aldo/keto reductase, putative 0.0037 0.0084 0.0084
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.3228 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.001 0.0001 0.0001
Trichomonas vaginalis set domain proteins, putative 0.0274 0.082 0.402
Loa Loa (eye worm) hypothetical protein 0.0029 0.006 0.0059
Schistosoma mansoni phosphoglycerate mutase 0.0054 0.0139 0.0139
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0015 0.0017 0.0028
Onchocerca volvulus Serine\/threonine kinase homolog 0.0102 0.0287 0.0286
Entamoeba histolytica hypothetical protein 0.0033 0.007 0.0119
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0027 0.0027
Onchocerca volvulus 0.0039 0.0089 0.0088
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0015 0.0017 0.0169
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0035 0.0077 0.0077
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0027 0.0277
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0035 0.0059
Echinococcus multilocularis phd:f box containing protein 0.001 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0012
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0101 0.0282 0.2855
Loa Loa (eye worm) oxidoreductase 0.0037 0.0084 0.0083
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0067 0.4727
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1377 0.4249 0.4249
Brugia malayi jmjC domain containing protein 0.0103 0.0291 0.3065
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0016 0.0016
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.0054 0.0139 0.0139
Brugia malayi PHD-finger family protein 0.0012 0.0006 0.006
Schistosoma mansoni potassium channel beta 0.0011 0.0002 0.0002
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0054 0.0139 0.1392
Trypanosoma brucei prostaglandin f synthase 0.0037 0.0084 0.0084
Plasmodium falciparum aldehyde reductase, putative 0.0011 0.0002 0.0171
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0067
Brugia malayi Thioredoxin reductase 0.0044 0.0106 0.1115
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0054 0.0139 0.0139
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0001 0.009
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0095 0.0463
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0006
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.0054 0.0139 0.1392
Schistosoma mansoni hypothetical protein 0.0054 0.0139 0.0139
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1377 0.4249 0.4249
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0025 0.0047 0.3386
Toxoplasma gondii histone lysine-specific demethylase 0.0025 0.0047 0.3294
Echinococcus multilocularis lamin dm0 0.0029 0.006 0.006
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0112 0.0316 0.3211
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0016 0.0075
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0027 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Brugia malayi Cathepsin L-like precursor 0.0015 0.0016 0.0165
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0046
Leishmania major hypothetical protein, conserved 0.0054 0.0139 0.0139
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0006 0.0006
Mycobacterium ulcerans bifunctional RNase H/acid phosphatase 0.0054 0.0139 0.0235
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Onchocerca volvulus 0.0029 0.006 0.0059
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.0054 0.0139 0.1392
Plasmodium falciparum JmjC domain-containing protein, putative 0.001 0.0001 0.0064
Onchocerca volvulus 0.0106 0.0297 0.0296
Brugia malayi steroid hormone receptor 0.0019 0.0027 0.0277
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0027 0.0027
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Toxoplasma gondii thioredoxin reductase 0.0044 0.0106 0.7454
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0016 0.0075
Trichomonas vaginalis aldo/keto reductase, putative 0.0037 0.0084 0.0407
Onchocerca volvulus Protein UBASH3A homolog 0.0054 0.0139 0.0138
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.3228 1 1
Leishmania major trypanothione reductase 0.0044 0.0106 0.0106
Echinococcus granulosus phosphoglycerate mutase 0.0054 0.0139 0.0139
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0027 0.0027
Echinococcus granulosus cpg binding protein 0.003 0.0064 0.0064
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0666 0.2039 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.007 0.0341
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0046
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0013 0.0013
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0059 0.0058
Giardia lamblia Hypothetical protein 0.1905 0.5889 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0089 0.0089
Brugia malayi Sodium:solute symporter family protein 0.0035 0.0077 0.0806
Mycobacterium tuberculosis Conserved protein 0.0054 0.0139 0.1392
Echinococcus granulosus RUN 0.0039 0.0089 0.0089
Loa Loa (eye worm) oxidoreductase 0.0037 0.0084 0.0083
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0027 0.0027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0025 0.0047 0.0455
Brugia malayi SWIRM domain containing protein 0.0025 0.0047 0.0488
Leishmania major hypothetical protein, unknown function 0.0054 0.0139 0.0139
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.1851 0.572 0.572
Trypanosoma cruzi cruzipain precursor, putative 0.0058 0.0149 0.0149
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0015 0.0017 0.1203
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.007 0.4401
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0016 0.0028
Brugia malayi glutathione reductase 0.0044 0.0106 0.1115
Plasmodium falciparum thioredoxin reductase 0.0044 0.0106 0.7661
Entamoeba histolytica serine/threonine protein kinase, putative 0.0102 0.0287 0.0487
Giardia lamblia PHD finger protein 15 0.0032 0.0067 0.0086
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0054 0.0139 0.0235
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.1905 0.5889 1
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0025 0.0047 0.3386
Brugia malayi 6-phosphofructokinase 0.0121 0.0344 0.3628
Giardia lamblia Aldose reductase 0.0037 0.0084 0.0114
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Schistosoma mansoni rab6-interacting 0.0039 0.0089 0.0089
Plasmodium vivax phosphoglycerate mutase, putative 0.0054 0.0139 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0001
Giardia lamblia Hypothetical protein 0.1905 0.5889 1
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0054 0.0139 0.0139
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0027 0.0277
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.035 0.0349
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0011
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0047 0.3386
Echinococcus granulosus aldo keto reductase 0.0037 0.0084 0.0084
Brugia malayi jmjC domain containing protein 0.004 0.0093 0.0977
Loa Loa (eye worm) hypothetical protein 0.3173 0.9831 0.9831
Trichomonas vaginalis mercuric reductase, putative 0.0015 0.0017 0.0078
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0035 0.0035
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0095 0.0161
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.0047 0.0047
Onchocerca volvulus Cathepsin L homolog 0.0015 0.0016 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0341
Brugia malayi Cathepsin L-like precursor 0.0015 0.0016 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0139 0.0676
Entamoeba histolytica alcohol dehydrogenase, putative 0.0011 0.0002 0.0004
Echinococcus multilocularis RUN 0.0039 0.0089 0.0089
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0103 0.0291 0.0291
Plasmodium falciparum glutathione reductase 0.0015 0.0017 0.1203
Giardia lamblia Kinase, PLK 0.0102 0.0287 0.046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Echinococcus granulosus JmjC domain containing protein 4 0.001 0.0001 0.0001
Mycobacterium ulcerans phosphoglycerate mutase 0.0054 0.0139 0.0235
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0231 0.0687 0.0687
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.0054 0.0139 0.1392
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0037 0.0084 0.0084
Toxoplasma gondii phosphoglycerate mutase family protein 0.0054 0.0139 0.9729
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0017 0.0017
Echinococcus granulosus lysosomal alpha glucosidase 0.0182 0.0536 0.0536
Mycobacterium leprae probable isochorismate synthase EntC 0.0054 0.0139 0.1392
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0002 0.0008
Plasmodium falciparum protoporphyrinogen oxidase 0.0025 0.0047 0.3386
Treponema pallidum phosphoglyceromutase 0.0054 0.0139 0.0603
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.012 0.0343 0.0343
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.001 0.0001 0.0062
Echinococcus granulosus cathepsin L cysteine proteinase 0.0015 0.0016 0.0016
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0015 0.0017 0.0017
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0016 0.0028
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0016 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0027 0.0026
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0078 0.0078
Loa Loa (eye worm) 6-phosphofructokinase 0.012 0.0343 0.0343
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.0054 0.0139 0.1392
Echinococcus multilocularis voltage gated potassium channel subunit 0.0011 0.0002 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0163 0.0163
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0054 0.0139 0.0139
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0027 0.0027
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0078 0.0078
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0011 0.0002 0.0166
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0095 0.0095
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0011 0.0004 0.0035
Echinococcus granulosus intermediate filament protein 0.0029 0.006 0.006
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0035 0.033
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0095 0.0463
Giardia lamblia Aldose reductase 0.0037 0.0084 0.0114
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0015 0.0017 0.0017
Schistosoma mansoni cellular tumor antigen P53 0.0045 0.0108 0.0108
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0054 0.0139 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Loa Loa (eye worm) glutathione reductase 0.0044 0.0106 0.0105
Schistosoma mansoni inositol transporter 0.0035 0.0077 0.0077
Onchocerca volvulus 0.0045 0.0108 0.0108
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.0054 0.0139 0.0139
Echinococcus multilocularis aldo keto reductase 0.0037 0.0084 0.0084
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0095 0.0463
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0054 0.0139 0.0676
Schistosoma mansoni ap endonuclease 0.0021 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0054 0.0139 0.0138
Schistosoma mansoni jumonji domain containing protein 0.0082 0.0224 0.0224
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.007 0.5075
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0015 0.0017 0.1171
Brugia malayi Pre-SET motif family protein 0.0241 0.0717 0.7577
Onchocerca volvulus 0.0037 0.0084 0.0083
Echinococcus multilocularis protoporphyrinogen oxidase 0.0025 0.0047 0.0047
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.3228 1 1
Mycobacterium ulcerans hydrolase MutT1 0.0054 0.0139 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0027 0.0277
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0054 0.0139 0.0139
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0149 0.0149
Brugia malayi nuclear hormone receptor 0.0019 0.0027 0.0277
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0037 0.0084 0.0877
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0013 0.0013
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0341
Onchocerca volvulus 0.0039 0.0089 0.0088
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0015 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Brugia malayi serine/threonine-protein kinase plk-2 0.0102 0.0287 0.3029
Schistosoma mansoni ap endonuclease 0.0021 0.0035 0.0035
Onchocerca volvulus 0.0037 0.0084 0.0083
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0011 0.0002 0.0166
Schistosoma mansoni lamin 0.0029 0.006 0.006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0198 0.0586 0.0586
Schistosoma mansoni kinase 0.0052 0.0131 0.0131
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0027 0.0027
Entamoeba histolytica aldose reductase, putative 0.0037 0.0084 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0666 0.2039 1
Brugia malayi amine oxidase, flavin-containing family protein 0.0025 0.0047 0.0488
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0095 0.0463
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0015 0.0016 0.1175
Trypanosoma cruzi aldo/keto reductase, putative 0.0011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0026
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.012 0.0343 0.1615
Mycobacterium ulcerans hypothetical protein 0.0054 0.0139 0.0235
Loa Loa (eye worm) phosphoglycerate mutase 0.0054 0.0139 0.0138
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0035 0.0031
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0015 0.0016 0.0016
Loa Loa (eye worm) oxidoreductase 0.0037 0.0084 0.0083
Plasmodium falciparum cysteine proteinase falcipain 3 0.0015 0.0016 0.1175
Plasmodium vivax glutathione reductase, putative 0.0044 0.0106 0.7661
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.001 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0027 0.0027
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0037 0.0084 0.0084
Plasmodium falciparum aldo-keto reductase, putative 0.0011 0.0002 0.0171
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0035 0.0035
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0027 0.0027
Brugia malayi hypothetical protein 0.0039 0.0089 0.0936
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0027 0.0026
Brugia malayi intermediate filament protein 0.0029 0.006 0.0627
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0089 0.6436
Echinococcus multilocularis 6 phosphofructokinase 0.012 0.0343 0.0343
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.3228 1 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0027 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0287 0.1405
Loa Loa (eye worm) glutaminase 2 0.0306 0.092 0.092
Brugia malayi nuclear receptor NHR-88 0.0019 0.0027 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0027 0.0277
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0037 0.0084 0.0407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Echinococcus multilocularis cysteine protease 0.0015 0.0016 0.0016
Toxoplasma gondii phosphoglycerate mutase 0.0054 0.0139 0.9729
Entamoeba histolytica cysteine protease, putative 0.0015 0.0016 0.0028
Echinococcus granulosus aldo keto reductase 0.0037 0.0084 0.0084
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0015 0.0017 0.0017
Schistosoma mansoni cpg binding protein 0.0029 0.0059 0.0059
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0054 0.0139 0.0138
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0325 0.098 1
Loa Loa (eye worm) 6-phosphofructokinase 0.012 0.0343 0.0343
Mycobacterium ulcerans hypothetical protein 0.0011 0.0002 0.0004
Schistosoma mansoni 6-phosphofructokinase 0.012 0.0343 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Toxoplasma gondii aldo-keto reductase 0.0011 0.0002 0.0166
Trypanosoma cruzi major cysteine proteinase, putative 0.0045 0.011 0.011
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0343 0.0583
Onchocerca volvulus Cathepsin F homolog 0.0015 0.0016 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0341
Schistosoma mansoni 6-phosphofructokinase 0.012 0.0343 0.0343
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.0287 0.0287
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0054 0.0139 0.0676
Leishmania major phosphoglycerate mutase family member 5, putative 0.0054 0.0139 0.0139
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0037 0.0084 0.0877
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0054 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0016
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0409 0.1242 0.1242
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0666 0.2039 0.3463
Onchocerca volvulus 0.0035 0.0077 0.0076
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0015 0.0016 0.0076
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0054 0.0139 0.0139
Plasmodium vivax phosphoglucomutase-2, putative 0.0054 0.0139 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0027 0.0277
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.007 0.0091
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0025 0.0047 0.008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0015 0.0016 0.0016
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0093 0.0093
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0011 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0027 0.0027
Schistosoma mansoni cpg binding protein 0.003 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Trichomonas vaginalis phosphofructokinase, putative 0.012 0.0343 0.1681
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0027 0.0026
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0037 0.0084 0.0407
Schistosoma mansoni amine oxidase 0.0025 0.0047 0.0047
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.001 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0035 0.0035
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0054 0.0139 0.1392
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Onchocerca volvulus 0.0015 0.0016 0.0016
Loa Loa (eye worm) glutaminase 0.0306 0.092 0.092
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0016 0.0016
Brugia malayi Cathepsin L-like precursor 0.0015 0.0016 0.0165
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0025 0.0047 0.0455
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0182 0.0536 0.0535
Echinococcus multilocularis phosphoglycerate mutase 0.0054 0.0139 0.0139
Echinococcus multilocularis jumonji domain containing 1A 0.001 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0054 0.0139 0.0139
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.007 0.4937
Brugia malayi UBASH3A protein homolog 0.0054 0.0139 0.1458
Brugia malayi NADH-dependent xylose reductase 0.0011 0.0002 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0095 0.0463
Echinococcus multilocularis phosphoglycerate mutase 0.0054 0.0139 0.0139
Plasmodium falciparum phosphoglucomutase-2 0.0054 0.0139 1
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0037 0.0084 0.0407
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0016 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0027 0.0026
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0015 0.0017 0.0017
Echinococcus multilocularis phosphoglycerate mutase 0.0054 0.0139 0.0139
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0018 0.0181
Loa Loa (eye worm) oxidoreductase 0.0037 0.0084 0.0083
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0015 0.0017 0.0017
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0025 0.0047 0.008
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0016 0.0075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0198 0.0586 0.0586
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.007 0.0119
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0666 0.2039 1
Plasmodium vivax vivapain-2 0.0015 0.0016 0.1175
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0017 0.0017
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0054 0.0139 0.0676
Onchocerca volvulus Protein UBASH3A homolog 0.0054 0.0139 0.0138
Mycobacterium leprae conserved hypothetical protein 0.0054 0.0139 0.1392
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0058
Echinococcus granulosus jumonji domain containing 1A 0.001 0.0001 0.0001
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0035 0.0077 0.0077
Leishmania major cathepsin L-like protease 0.0058 0.0149 0.0149
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0101 0.0282 0.2855
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0341
Echinococcus multilocularis aldo keto reductase 0.0037 0.0084 0.0084
Schistosoma mansoni sodium/solute symporter 0.0035 0.0077 0.0077
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0035 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Schistosoma mansoni hypothetical protein 0.0764 0.2345 0.2345
Schistosoma mansoni aldo-keto reductase 0.0037 0.0084 0.0084
Trichomonas vaginalis aldo-keto reductase, putative 0.0011 0.0002 0.0008
Onchocerca volvulus 0.0015 0.0016 0.0016
Mycobacterium leprae conserved hypothetical protein 0.0054 0.0139 0.1392
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0666 0.2039 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0666 0.2039 1
Echinococcus granulosus phosphoglycerate mutase 0.0054 0.0139 0.0139
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0016 0.0075
Echinococcus multilocularis lamin 0.0029 0.006 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Schistosoma mansoni phosphoglycerate mutase 0.0054 0.0139 0.0139
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0198 0.0586 0.0586
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0106 0.0106
Leishmania major ATP-dependent phosphofructokinase 0.012 0.0343 0.0343
Schistosoma mansoni cpg binding protein 0.003 0.0064 0.0064
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0054 0.0139 0.0676
Brugia malayi Bromodomain containing protein 0.0032 0.0067 0.0704
Trypanosoma cruzi trypanothione reductase, putative 0.0015 0.0017 0.0017
Brugia malayi phosphofructokinase 0.012 0.0343 0.3625
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0198 0.0586 0.6185
Mycobacterium ulcerans dehydrogenase 0.0025 0.0047 0.008
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0037 0.0084 0.0084
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0019 0.0027 0.0026
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.3173 0.9831 0.9831
Leishmania major cysteine peptidase A (CPA) 0.0015 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Trypanosoma brucei trypanothione reductase 0.0044 0.0106 0.0106
Loa Loa (eye worm) thioredoxin reductase 0.0044 0.0106 0.0105
Brugia malayi phosphoglycerate mutase family protein 0.0054 0.0139 0.1458
Leishmania major cathepsin L-like protease 0.0015 0.0016 0.0016
Leishmania major aldo-keto reductase-like protein 0.0037 0.0084 0.0084
Schistosoma mansoni transcription factor LCR-F1 0.0033 0.007 0.007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0054 0.0139 0.1392
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0025 0.0047 0.0047
Onchocerca volvulus Protein ultraspiracle homolog 0.0019 0.0027 0.0026
Schistosoma mansoni hypothetical protein 0.0764 0.2345 0.2345
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0015 0.0017 0.0028
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.0536 0.0536
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0054 0.0139 0.0139
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0103 0.0291 0.0291
Onchocerca volvulus 0.0054 0.0139 0.0138
Schistosoma mansoni amine oxidase 0.0025 0.0047 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0287 0.1405
Brugia malayi MH2 domain containing protein 0.0122 0.035 0.3689
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0095 0.0463
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0095 0.0463
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0026
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0015 0.0017 0.1203
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0287 0.1405
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.006 0.0059
Leishmania major cathepsin L-like protease 0.0015 0.0016 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0027 0.0027
Schistosoma mansoni aldo-keto reductase 0.0037 0.0084 0.0084
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.006 0.0627
Leishmania major UDP-galactopyranose mutase 0.0025 0.0047 0.0047
Plasmodium vivax SET domain protein, putative 0.0035 0.0078 0.5641
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Trypanosoma brucei aldo-keto reductase, putative 0.0037 0.0084 0.0084
Plasmodium vivax JmjC domain containing protein 0.001 0.0001 0.0064
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0112 0.0316 0.3211
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0017 0.0017
Entamoeba histolytica phosphofructokinase, putative 0.012 0.0343 0.0583
Echinococcus multilocularis aldo keto reductase 0.0037 0.0084 0.0084
Trichomonas vaginalis aldo-keto reductase, putative 0.0011 0.0002 0.0008
Entamoeba histolytica aldose reductase, putative 0.0037 0.0084 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0025 0.0047 0.008
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0035 0.0059
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0095 0.6671
Onchocerca volvulus 0.0025 0.0047 0.0046
Plasmodium falciparum glutathione reductase 0.0044 0.0106 0.7661
Echinococcus granulosus lamin dm0 0.0029 0.006 0.006
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0027 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0027 0.0277
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0054 0.0139 0.0139
Schistosoma mansoni glutaminase 0.0306 0.092 0.092
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0078 0.0078
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Echinococcus multilocularis phosphoglycerate mutase 0.0054 0.0139 0.0139
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0054 0.0139 0.0235
Mycobacterium ulcerans monoamine oxidase 0.0025 0.0047 0.008
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0015 0.0017 0.0028
Brugia malayi Doublecortin family protein 0.0039 0.0089 0.0936
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0015 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0016 0.0076
Loa Loa (eye worm) hypothetical protein 0.3228 1 1
Leishmania major cathepsin L-like protease 0.0015 0.0016 0.0016
Echinococcus multilocularis 0.0025 0.0047 0.0047
Echinococcus granulosus lysine specific demethylase 6a 0.001 0.0001 0.0001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0037 0.0084 0.0084
Trichomonas vaginalis aldo-keto reductase, putative 0.0037 0.0084 0.0407
Brugia malayi Cathepsin L-like precursor 0.0015 0.0016 0.0165
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0078 0.0078
Onchocerca volvulus 0.0015 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0033 0.007 0.0119
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0011 0.0004 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0666 0.2039 1
Leishmania major cathepsin L-like protease 0.0058 0.0149 0.0149
Onchocerca volvulus 0.0274 0.082 0.0819
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0054 0.0139 0.0139
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0033 0.007 0.007
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0016 0.0075
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0192 0.0565 0.0564
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Echinococcus multilocularis aldehyde reductase 0.0026 0.0051 0.0051
Schistosoma mansoni phosphatidylserine receptor 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0089 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0287 0.0287
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0149 0.0149
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0101 0.0282 0.2855
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.0054 0.0139 0.1392
Toxoplasma gondii phosphoglycerate mutase family protein 0.0054 0.0139 0.9729
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0015 0.0017 0.1203
Brugia malayi Glycosyl hydrolases family 31 protein 0.0182 0.0536 0.5663
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0325 0.098 1
Brugia malayi jmjC domain containing protein 0.001 0.0001 0.0002
Toxoplasma gondii aldose reductase, putative 0.0037 0.0084 0.5873
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0035 0.0359
Mycobacterium ulcerans phosphoglycerate mutase 0.0054 0.0139 0.0235
Brugia malayi GH02984p 0.0314 0.0946 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0015 0.0017 0.0017
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0027 0.0277
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0054 0.0139 0.0139
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0047 0.3386
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.0054 0.0139 0.0139
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.0054 0.0139 0.0235
Mycobacterium tuberculosis Probable dehydrogenase 0.0101 0.0282 0.2855
Schistosoma mansoni hypothetical protein 0.0039 0.0089 0.0089
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0007 0.0486
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0067 0.0067
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1377 0.4249 0.4249
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0027 0.0027
Schistosoma mansoni lipoxygenase 0.0161 0.0471 0.0471
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.035 0.0349
Schistosoma mansoni hypothetical protein 0.0054 0.0139 0.0139
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0027 0.0027
Mycobacterium leprae Conserved hypothetical protein 0.0026 0.0051 0.0492
Toxoplasma gondii phosphoglycerate mutase family protein 0.0054 0.0139 0.9729
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0101 0.0282 0.2855
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0011
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0027 0.0027
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0054 0.0139 0.0139
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0231 0.0687 0.0687
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.007 0.4937
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0015 0.0017 0.0017
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0025 0.0047 0.0047
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0027 0.0027
Echinococcus granulosus geminin 0.0764 0.2345 0.2345
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.0047 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0341
Brugia malayi PHD-finger family protein 0.0032 0.0067 0.0704
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0287 0.1405
Echinococcus multilocularis tumor protein p63 0.0306 0.0919 0.0919
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0101 0.0282 0.2855
Echinococcus granulosus tumor protein p63 0.0306 0.0919 0.0919
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0035 0.0089
Toxoplasma gondii cathepsin CPL 0.0015 0.0016 0.1143
Echinococcus multilocularis cysteine protease 0.0015 0.0016 0.0016
Onchocerca volvulus 0.0037 0.0084 0.0083
Onchocerca volvulus 0.0054 0.0139 0.0138
Mycobacterium tuberculosis Conserved protein 0.0054 0.0139 0.1392
Schistosoma mansoni polycystin 1-related 0.0039 0.0089 0.0089
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.0047 0.0047
Brugia malayi glutaminase DH11.1 0.0306 0.092 0.9727
Echinococcus multilocularis cpg binding protein 0.003 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0016 0.0076
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0102 0.0287 0.0287
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0287 0.1405
Onchocerca volvulus Bile acid receptor homolog 0.0019 0.0027 0.0026
Echinococcus granulosus aldo keto reductase 0.0037 0.0084 0.0084
Echinococcus granulosus hypothetical protein 0.0037 0.0084 0.0084
Brugia malayi ecdysteroid receptor 0.0019 0.0027 0.0277

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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