Detailed information for compound 2072859

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 417.303 | Formula: C18H21BrN6O
  • H donors: 0 H acceptors: 4 LogP: 1.1 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cn1ncc(c1)CN1CCOC(C1)c1cccc(n1)c1cncnc1.Br
  • InChi: 1S/C18H20N6O.BrH/c1-23-10-14(7-21-23)11-24-5-6-25-18(12-24)17-4-2-3-16(22-17)15-8-19-13-20-9-15;/h2-4,7-10,13,18H,5-6,11-12H2,1H3;1H
  • InChiKey: SCKBSFDJUHKLNL-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0007 0.1372
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni histamine h1 receptor 0.0038 0.002 0.002
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Entamoeba histolytica major facilitator superfamily protein 0.0013 0.0003 0.2304
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.2304
Plasmodium falciparum pantothenate transporter 0.0013 0.0003 0.0978
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.002 0.002
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0012 0.0012
Brugia malayi Dopamine receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Giardia lamblia hypothetical protein 0.0013 0.0003 0.4205
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.002 0.002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0007 0.0006
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0007 0.0007
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0027 0.0012 0.0012
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.002 0.002
Onchocerca volvulus Putative solute carrier family 17, member 7 0.0013 0.0003 0.0002
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0003 0.0978
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0013 0.0003 0.0002
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0013 0.0003 0.007
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0007 0.0443
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.002 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.002 0.002
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0003 0.0978
Toxoplasma gondii hypothetical protein 0.0013 0.0003 0.0174
Schistosoma mansoni ap endonuclease 0.0019 0.0007 0.0007
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0005
Loa Loa (eye worm) ACC-1 protein 0.0011 0.0001 0.0001
Plasmodium falciparum glutathione reductase 0.0054 0.0031 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Echinococcus granulosus synaptic vesicle 2 protein 0.0013 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0158 0.0103 0.0103
Echinococcus multilocularis vesicular glutamate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0003 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.002 0.002
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.002 0.002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Onchocerca volvulus 0.0038 0.002 0.0019
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0011 0.0001 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0013 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Leishmania major MFS transporter, putative 0.0013 0.0003 0.0001
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni phosphate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Schistosoma mansoni sodium-dependent amino acid transporter 0.0027 0.0012 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0007 0.0286
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.002 0.002
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0138 0.0089 1
Brugia malayi neuropeptide F receptor 0.0038 0.002 0.002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.002 0.002
Echinococcus multilocularis glycine receptor subunit beta 0.0011 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Schistosoma mansoni biogenic amine receptor 0.0038 0.002 0.002
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Echinococcus granulosus synaptic vesicular amine transporter 0.0013 0.0003 0.0003
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Echinococcus granulosus somatostatin receptor 0.0038 0.002 0.002
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0011 0.0001 0.0001
Schistosoma mansoni inositol transporter 0.104 0.0709 0.0709
Brugia malayi excitatory GABA receptor EXP-1A 0.0011 0.0001 0.0001
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Onchocerca volvulus 0.0038 0.002 0.0019
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Onchocerca volvulus 0.0013 0.0003 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0007 0.0006
Trypanosoma brucei riboflavin transporter 0.0013 0.0003 0.0001
Toxoplasma gondii hypothetical protein 0.0027 0.0012 0.07
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Toxoplasma gondii hypothetical protein 0.0027 0.0012 0.07
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0007 0.0007
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus dna polymerase eta 0.0019 0.0007 0.0007
Entamoeba histolytica sucrose transporter, putative 0.0013 0.0003 0.2304
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.002 0.002
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0013 0.0003 0.007
Brugia malayi Thioredoxin reductase 0.0054 0.0031 0.0031
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Echinococcus multilocularis solute carrier family 5 0.104 0.0709 0.0709
Plasmodium falciparum monocarboxylate transporter, putative 0.0013 0.0003 0.0978
Echinococcus granulosus MFS transporter ceroid lipofuscinosis neuronal 0.0013 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0005
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.002 0.002
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.0158 0.0158
Echinococcus multilocularis allatostatin A receptor 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Brugia malayi probable sodium-dependent inorganic phosphate cotransporter 0.0013 0.0003 0.0003
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0007 0.0492
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.002 0.002
Trichomonas vaginalis transport proetin, putative 0.0013 0.0003 0.007
Trypanosoma cruzi major facilitator superfamily, putative 0.0013 0.0003 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Echinococcus granulosus vesicular acetylcholine transporter 1.4562 1 1
Schistosoma mansoni feline leukemia virus subgroup C receptor-related 0.0013 0.0003 0.0003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.002 0.002
Echinococcus multilocularis thioredoxin glutathione reductase 0.0054 0.0031 0.0031
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.024 0.0159 0.0159
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0007 0.0007
Schistosoma mansoni transporter spinster-related 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0007 0.0005
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni tetracycline-efflux transporter 0.0013 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0019 0.0007 0.8997
Trypanosoma brucei Protein Associated with Differentiation 1 0.0013 0.0003 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.002 0.002
Echinococcus multilocularis sodium:myo inositol cotransporter 0.104 0.0709 0.0709
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0038 0.002 0.002
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.002 0.002
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.0138 0.0089 1
Echinococcus multilocularis geminin 0.0366 0.0246 0.0246
Leishmania major C-8 sterol isomerase-like protein 1.3484 0.926 1
Brugia malayi RE15519p 0.0038 0.002 0.002
Schistosoma mansoni sodium-dependent phosphate transporter 0.0013 0.0003 0.0003
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0007 0.0389
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.002 0.002
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0013 0.0003 0.007
Plasmodium falciparum thioredoxin reductase 0.0019 0.0007 0.219
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.024 0.0159 0.0159
Onchocerca volvulus 0.0013 0.0003 0.0002
Onchocerca volvulus 0.0038 0.002 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0009 0.0384
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.002 0.002
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0265 0.0176 0.0176
Plasmodium vivax amine transporter, putative 0.0027 0.0012 0.3284
Brugia malayi G-protein coupled receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis somatostatin receptor 0.0038 0.002 0.002
Loa Loa (eye worm) norepinephrine transporter 0.0158 0.0103 0.0103
Echinococcus multilocularis neuropeptide receptor 0.0038 0.002 0.002
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.002 0.002
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0158 0.0103 0.0103
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.002 0.002
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Leishmania major transporter-like protein 0.0013 0.0003 0.0001
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis sugar phosphate exchanger 3 0.0013 0.0003 0.0003
Trypanosoma brucei transporter protein, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.002 0.002
Schistosoma mansoni sialin (solute carrier family 17 member 5) (sodium/sialic acid cotransporter) (ast) (membrane glycoprotein hp59) 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Trypanosoma cruzi integral membrane transport protein, putative 0.0013 0.0003 0.0001
Echinococcus granulosus bloom syndrome protein 0.0022 0.0009 0.0009
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Echinococcus granulosus g-protein coupled receptor 0.0038 0.002 0.002
Leishmania major DNA polymerase eta, putative 0.0019 0.0007 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0005
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis Glycerol 3 phosphate transporter 0.0013 0.0003 0.0003
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4205
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0019 0.0007 0.8997
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0012 0.3284
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Giardia lamblia Multidrug resistance protein B 0.0013 0.0003 0.4205
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0007 0.0006
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0013 0.0003 0.0003
Trypanosoma brucei transporter, putative 0.0013 0.0003 0.0001
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0004 0.0297
Brugia malayi Cation transporter family protein 0.0011 0.0001 0.0001
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.002 0.002
Trypanosoma brucei protein associated with differentiation 8, putative 0.0013 0.0003 0.0001
Brugia malayi Dopamine receptor protein 1 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) thioredoxin reductase 0.0054 0.0031 0.0031
Schistosoma mansoni opsin-like receptor 0.0038 0.002 0.002
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni transport proetin (smap-4-related) 0.0013 0.0003 0.0003
Trypanosoma cruzi protein associated with differentiation 8, putative 0.0013 0.0003 0.0001
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Schistosoma mansoni inositol transporter 0.104 0.0709 0.0709
Echinococcus granulosus glycine receptor subunit beta 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0017 0.0017
Brugia malayi GnHR receptor homolog 0.0038 0.002 0.002
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0003 0.0978
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0013 0.0003 0.0978
Echinococcus multilocularis orexin receptor type 2 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni biogenic amine receptor 0.0038 0.002 0.002
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Brugia malayi glutathione reductase 0.0054 0.0031 0.0031
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0038 0.002 0.0019
Brugia malayi Abnormal catecholamine distribution protein 1 0.0013 0.0003 0.0003
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Leishmania major hypothetical protein, unknown function 0.0013 0.0003 0.0001
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0007 0.0007
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.002 0.002
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Echinococcus granulosus sodium dependent phosphate transport protein 1 0.0013 0.0003 0.0003
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0013 0.0003 0.0003
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0007 0.9789
Echinococcus granulosus neuropeptide receptor A26 0.0038 0.002 0.002
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0011 0.0001 0.0001
Trypanosoma cruzi protein associated with differentiation 4, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0038 0.002 0.002
Brugia malayi Sodium:solute symporter family protein 0.0265 0.0176 0.0176
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0158 0.0103 0.0103
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0013 0.0003 0.0978
Echinococcus granulosus feline leukemia virus subgroup C 0.0013 0.0003 0.0003
Trypanosoma cruzi MFS transporter, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Brugia malayi transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0011 0.0001 0.0001
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0007 0.0006
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.002 0.002
Trypanosoma brucei trypanothione reductase 0.0054 0.0031 0.0032
Schistosoma mansoni neuropeptide receptor 0.0038 0.002 0.002
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0007 0.9377
Schistosoma mansoni opsin-like receptor 0.0038 0.002 0.002
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.002 0.002
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus granulosus Solute carrier family 22 5 0.0013 0.0003 0.0003
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4205
Echinococcus granulosus sodium:myo inositol cotransporter 0.104 0.0709 0.0709
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Echinococcus multilocularis solute carrier family 43 0.0013 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Brugia malayi ORL1-like opioid receptor 0.0038 0.002 0.002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0011 0.0001 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0005
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0124 0.0079 0.8889
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.0038 0.002 0.002
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Onchocerca volvulus 0.0013 0.0003 0.0002
Trypanosoma cruzi major facilitator superfamily, putative 0.0013 0.0003 0.0001
Schistosoma mansoni amine GPCR 0.0038 0.002 0.002
Trypanosoma cruzi hypothetical protein 0.0013 0.0003 0.0001
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Giardia lamblia MDR-type permease 0.0013 0.0003 0.4205
Echinococcus granulosus vesicular glutamate transporter 0.0013 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0003 0.0001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0007 0.0007
Onchocerca volvulus 0.0038 0.002 0.0019
Loa Loa (eye worm) hippocampus abundant transcript 1a 0.0013 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.2304
Schistosoma mansoni vesicular amine transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis neuropeptide s receptor 0.0038 0.002 0.002
Trypanosoma brucei protein associated with differentiation 3, putative 0.0013 0.0003 0.0001
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0007 0.219
Plasmodium vivax thioredoxin reductase, putative 0.0054 0.0031 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.002 0.002
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.002 0.002
Echinococcus multilocularis feline leukemia virus subgroup C 0.0013 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Toxoplasma gondii thioredoxin reductase 0.0054 0.0031 0.1776
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0007
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.002 0.002
Onchocerca volvulus 0.0034 0.0018 0.0016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0018 0.0994
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis vesicular glutamate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0013 0.0003 0.0003
Brugia malayi Cation transporter family protein 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0366 0.0246 0.0246
Onchocerca volvulus 0.0265 0.0176 0.0175
Onchocerca volvulus 0.0038 0.002 0.0019
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Echinococcus granulosus geminin 0.0366 0.0246 0.0246
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.002 0.002
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.002 0.002
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.002 0.002
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 1.4562 1 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0124 0.0079 0.8889
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Entamoeba histolytica major facilitator superfamily protein 0.0013 0.0003 0.2304
Loa Loa (eye worm) hypothetical protein 0.0239 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.002 0.002
Echinococcus granulosus sugar phosphate exchanger 0.0013 0.0003 0.0003
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0013 0.0003 0.0001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0007 0.0452
Onchocerca volvulus 0.0013 0.0003 0.0002
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.002 0.002
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.002 0.002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis hypothetical protein 0.0013 0.0003 0.007
Echinococcus multilocularis high affinity choline transporter 1 0.0265 0.0176 0.0176
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0265 0.0176 0.0176
Schistosoma mansoni amine GPCR 0.0038 0.002 0.002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0027 0.0012 0.0012
Echinococcus granulosus synaptic vesicle 2 protein 0.0013 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis nAChR subunit 0.0011 0.0001 0.0001
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.002 0.002
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.002 0.002
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0007 0.1343
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.002 0.002
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Schistosoma mansoni neuropeptide receptor 0.0038 0.002 0.002
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.002 0.0019
Treponema pallidum sodium- and chloride- dependent transporter 0.0158 0.0103 1
Echinococcus granulosus allatostatin A receptor 0.0038 0.002 0.002
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.002 0.002
Onchocerca volvulus 0.0013 0.0003 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trypanosoma brucei transporter, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis solute carrier family 43 0.0013 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0038 0.002 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0007
Onchocerca volvulus Sialin homolog 0.0013 0.0003 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.002 0.002
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.002 0.002
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.0031 0.0032
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.002 0.002
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Trypanosoma brucei protein associated with differentiation 6, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0007 0.0282
Echinococcus granulosus high affinity choline transporter 1 0.0265 0.0176 0.0176
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0124 0.0079 0.8889
Onchocerca volvulus 0.0027 0.0012 0.0011
Onchocerca volvulus 0.0038 0.002 0.0019
Echinococcus multilocularis sex peptide receptor 0.0038 0.002 0.002
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.07
Schistosoma mansoni feline leukemia virus subgroup C receptor-related 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Onchocerca volvulus 0.0038 0.002 0.0019
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0007 0.2203
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0049 0.0027 0.0027
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0012 0.0012
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0007 0.0007
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0011 0.0001 0.0001
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0011 0.0001 0.0001
Echinococcus granulosus fmrfamide receptor 0.0038 0.002 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0007 0.0286
Onchocerca volvulus 0.0038 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis sodium dependent phosphate transport protein 1 0.0013 0.0003 0.0003
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Onchocerca volvulus Vesicular acetylcholine transporter homolog 1.4562 1 1
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0012 0.0012
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0366 0.0246 0.0246
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0003
Echinococcus granulosus orexin receptor type 2 0.0038 0.002 0.002
Schistosoma mansoni drug efflux protein-related 0.0013 0.0003 0.0003
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis serotonin transporter 0.0158 0.0103 0.0103
Onchocerca volvulus 0.0038 0.002 0.0019
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Onchocerca volvulus 0.0038 0.002 0.0019
Echinococcus multilocularis synaptic vesicular amine transporter 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0013 0.0003 0.0002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis synaptic vesicle 2 protein 0.0013 0.0003 0.0003
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.002 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Echinococcus granulosus sodium:glucose cotransporter 0.104 0.0709 0.0709
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.002 0.002
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0011 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Giardia lamblia Sugar transport family protein 0.0013 0.0003 0.4205
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.002 0.002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0007 0.0007
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.002 0.002
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0013 0.0003 0.0003
Brugia malayi Cation transporter family protein 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0007 0.0005
Echinococcus granulosus glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.002 0.002
Schistosoma mansoni sugar transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) RecQ helicase 0.0022 0.0009 0.0009
Echinococcus granulosus glycine receptor subunit beta 0.0011 0.0001 0.0001
Echinococcus multilocularis transfer RNA-Leu 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0013 0.0003 0.0002
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4205
Schistosoma mansoni vesicular amine transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.002 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Trypanosoma brucei major facilitator superfamily protein (MFS), putative 0.0013 0.0003 0.0001
Trypanosoma brucei protein associated with differentiation 4, putative 0.0013 0.0003 0.0001
Trichomonas vaginalis glucose-6-phosphate translocase, putative 0.0013 0.0003 0.007
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Brugia malayi sulfakinin receptor protein 0.0038 0.002 0.002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0007
Onchocerca volvulus 0.0049 0.0027 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Echinococcus granulosus protein spinster 0.0013 0.0003 0.0003
Brugia malayi Serotonin receptor 0.0038 0.002 0.002
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Giardia lamblia TM efflux prot 0.0013 0.0003 0.4205
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0018 0.0018
Schistosoma mansoni sodium/solute symporter 0.0265 0.0176 0.0176
Onchocerca volvulus 0.0013 0.0003 0.0002
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0011 0.0001 0.0001
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0007 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0005
Echinococcus granulosus solute carrier family 43 0.0013 0.0003 0.0003
Echinococcus granulosus thioredoxin glutathione reductase 0.0054 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0007 0.219
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Echinococcus granulosus g protein coupled receptor 0.0038 0.002 0.002
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0007 0.0006
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0007 0.0007
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0019 0.0007 0.409
Loa Loa (eye worm) hypothetical protein 0.0158 0.0103 0.0103
Onchocerca volvulus 0.0273 0.0181 0.018
Leishmania major monocarboxylate transporter-like protein 0.0013 0.0003 0.0001
Schistosoma mansoni biogenic amine receptor 0.0038 0.002 0.002
Echinococcus granulosus neuropeptide receptor 0.0038 0.002 0.002
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0007 0.0009
Schistosoma mansoni adenylate cyclase 0.0013 0.0003 0.0003
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0007 1
Brugia malayi AKH receptor 0.0038 0.002 0.002
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 1.3484 0.926 0.926
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0012 0.0012
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0124 0.0079 0.8889
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi C-8 sterol isomerase, putative 1.3484 0.926 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.002 0.002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.002 0.002
Schistosoma mansoni phosphate transporter 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0265 0.0176 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0011 0.0001 0.0001
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0005
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis glycine receptor subunit beta 0.0011 0.0001 0.0001
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0007 0.9191
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0011 0.0001 0.0001
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Schistosoma mansoni high-affinity choline transporter 0.0265 0.0176 0.0176
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.0012 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0158 0.0103 0.0103
Loa Loa (eye worm) ACC-1 protein 0.0011 0.0001 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.002 0.002
Trypanosoma cruzi protein associated with differentiation 8, putative 0.0013 0.0003 0.0001
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0009 0.0384
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0138 0.0089 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.002 0.002
Trypanosoma cruzi drug resistance protein, putative 0.0013 0.0003 0.0001
Onchocerca volvulus 0.0013 0.0003 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0007 0.9789
Loa Loa (eye worm) major facilitator superfamily transporter 0.0013 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0013 0.0003 0.0978
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.002 0.002
Plasmodium falciparum glutathione reductase 0.0019 0.0007 0.219
Echinococcus granulosus tm gpcr rhodopsin 0.3269 0.224 0.224
Echinococcus multilocularis oxalate:formate antiporter 0.0013 0.0003 0.0003
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0001 0.0001
Toxoplasma gondii hypothetical protein 0.0013 0.0003 0.0174
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Onchocerca volvulus 0.0013 0.0003 0.0002
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Entamoeba histolytica phosphate transporter, putative 0.0013 0.0003 0.2304
Onchocerca volvulus Sialin homolog 0.0013 0.0003 0.0002
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0007 0.0005
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Trypanosoma cruzi integral membrane transport protein, putative 0.0013 0.0003 0.0001
Schistosoma mansoni drug efflux protein-related 0.0013 0.0003 0.0003
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0007 0.0006
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Giardia lamblia NADH oxidase lateral transfer candidate 0.0019 0.0007 0.9419
Echinococcus multilocularis sodium:glucose cotransporter 2 0.104 0.0709 0.0709
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Giardia lamblia Major facilitator family transporter 0.0013 0.0003 0.4205
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0027 0.0012 0.0012
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.0012 0.0012
Schistosoma mansoni solute carrier family 17 member 7 (vesicular glutamate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.6892 0.473 0.473
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0018 0.0018
Trypanosoma brucei unspecified product 0.0019 0.0007 0.0006
Echinococcus granulosus serotonin transporter 0.0158 0.0103 0.0103
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.002 0.0019
Onchocerca volvulus Uncharacterized transporter homolog 0.0013 0.0003 0.0002
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0265 0.0176 0.0176
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0007 0.0282
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Trypanosoma brucei major facilitator superfamily, putative 0.0013 0.0003 0.0001
Onchocerca volvulus 0.0013 0.0003 0.0002
Echinococcus multilocularis dna polymerase eta 0.0019 0.0007 0.0007
Trypanosoma brucei C-8 sterol isomerase, putative 1.3484 0.926 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0018 0.0018
Echinococcus granulosus serotonin receptor 0.0038 0.002 0.002
Brugia malayi ERG2 and Sigma1 receptor like protein 1.3484 0.926 0.926
Onchocerca volvulus 0.0027 0.0012 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.002 0.002
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0007 0.0007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0038 0.002 0.0019
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0271 0.018 0.018
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.002 0.002
Echinococcus granulosus vesicular glutamate transporter 0.0013 0.0003 0.0003
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0011 0.0001 0.0001
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.002 0.002
Trypanosoma brucei protein associated with differentiation 7, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.002 0.002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Schistosoma mansoni amine GPCR 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus multilocularis MFS transporter ceroid lipofuscinosis neuronal 0.0013 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0011 0.0001 0.0001
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Plasmodium falciparum major facilitator superfamily-related transporter, putative 0.0013 0.0003 0.0978
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0011 0.0001 0.0001
Schistosoma mansoni solute carrier family 37 member 2 (glycerol-3-phosphate transporter 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0027 0.0012 0.0011
Echinococcus multilocularis serotonin receptor 0.0038 0.002 0.002
Onchocerca volvulus 0.0038 0.002 0.0019
Trypanosoma cruzi hypothetical protein 0.0013 0.0003 0.0001
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Plasmodium falciparum metabolite/drug transporter, putative 0.0013 0.0003 0.0978
Leishmania major trypanothione reductase 0.0054 0.0031 0.0032
Schistosoma mansoni vesicular acetylcholine transporter 1.4562 1 1
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis Hippocampus abundant transcript 1 protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0007 0.0006
Echinococcus multilocularis protein spinster 0.0013 0.0003 0.0003
Schistosoma mansoni sodium/sialic acid cotransporter 0.0013 0.0003 0.0003
Echinococcus multilocularis serotonin receptor 0.0038 0.002 0.002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.002 0.002
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.002 0.002
Trypanosoma brucei Protein Associated with Differentiation, putative 0.0013 0.0003 0.0001
Trypanosoma brucei unspecified product 0.0013 0.0003 0.0001
Plasmodium falciparum thioredoxin reductase 0.0054 0.0031 1
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0013 0.0003 0.007
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.002 0.002
Echinococcus granulosus neuropeptide s receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.002 0.002
Leishmania major integral membrane transport protein, putative,drug resistence protein, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Echinococcus multilocularis monocarboxylate transporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.07
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0018 0.0018
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0007 0.0005
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.002 0.002
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus granulosus major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma cruzi major facilitator superfamily, putative 0.0013 0.0003 0.0001
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Schistosoma mansoni survival motor neuron protein 0.0049 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus g protein coupled receptor 0.0038 0.002 0.002
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0011 0.0001 0.0001
Brugia malayi G protein-coupled receptor 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Onchocerca volvulus 0.0038 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Onchocerca volvulus 0.0158 0.0103 0.0101
Echinococcus granulosus glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Schistosoma mansoni protein transport protein Sec13 0.0013 0.0003 0.0003
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0007 0.0005
Brugia malayi neuropeptide F receptor 0.0038 0.002 0.002
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0007 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Probable reductase 0.0124 0.0079 0.8889
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma brucei protein associated with differentiation 5, putative 0.0013 0.0003 0.0001
Onchocerca volvulus Sugar phosphate exchanger 3 homolog 0.0013 0.0003 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.002 0.002
Leishmania major hypothetical protein, conserved 0.0013 0.0003 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.002 0.002
Onchocerca volvulus 0.0013 0.0003 0.0002
Brugia malayi larval opioid receptor 0.0038 0.002 0.002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0124 0.0079 0.8889
Echinococcus multilocularis MFS transporter ceroid lipofuscinosis neuronal 0.0013 0.0003 0.0003
Onchocerca volvulus 0.0013 0.0003 0.0002
Schistosoma mansoni neuropeptide receptor 0.0038 0.002 0.002
Plasmodium vivax SET domain protein, putative 0.0034 0.0018 0.5116
Echinococcus granulosus hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0007 0.0305
Trypanosoma cruzi transporter, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.002 0.002
Brugia malayi Dopamine receptor protein 2 0.0038 0.002 0.002
Brugia malayi hypothetical protein 0.0239 0.0158 0.0158
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0011 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.002 0.002
Brugia malayi putative neuropeptide receptor 0.0038 0.002 0.002
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4205
Giardia lamblia Multidrug resistance protein B 0.0013 0.0003 0.4205
Plasmodium vivax glutathione reductase, putative 0.0054 0.0031 1
Echinococcus granulosus monocarboxylate transporter 0.0013 0.0003 0.0003
Brugia malayi transporter 0.0013 0.0003 0.0003
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Brugia malayi hypothetical protein 0.0027 0.0012 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0011 0.0001 0.0001
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Echinococcus granulosus Hippocampus abundant transcript 1 protein 0.0013 0.0003 0.0003
Echinococcus multilocularis fmrfamide receptor 0.0038 0.002 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.002 0.002
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0138 0.0089 1
Leishmania major DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.002 0.002
Brugia malayi follicle stimulating hormone receptor 0.0271 0.018 0.018
Schistosoma mansoni adenoreceptor 0.0038 0.002 0.002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0007 0.0005
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.0012 0.0012
Echinococcus multilocularis vesicular acetylcholine transporter 1.4562 1 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0007 0.0006
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Onchocerca volvulus EG:103B4.3 protein homolog 0.0013 0.0003 0.0002
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0027 0.0012 0.0012
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Echinococcus multilocularis sugar phosphate exchanger solute carrier family 0.0013 0.0003 0.0003
Echinococcus granulosus oxalate:formate antiporter 0.0013 0.0003 0.0003
Trypanosoma brucei Protein Associated with Differentiation 0.0013 0.0003 0.0001
Plasmodium falciparum transporter, putative 0.0027 0.0012 0.3941
Brugia malayi Pre-SET motif family protein 0.0034 0.0018 0.0018
Brugia malayi Melatonin receptor type 1A 0.0038 0.002 0.002
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.002 0.002
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0013 0.0003 0.0003
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0007 0.0007
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0007 0.0007
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0019 0.0007 0.8997
Mycobacterium tuberculosis Probable dehydrogenase 0.0124 0.0079 0.8889
Leishmania major hypothetical protein, unknown function 0.0013 0.0003 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0038 0.002 0.002
Trichomonas vaginalis sucrose transport protein, putative 0.0013 0.0003 0.007
Brugia malayi G-protein coupled receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Hypothetical transporter C09D4.1 0.0013 0.0003 0.0003
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0011 0.0001 0.0001
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0011 0.0001 0.0001
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0007 0.0305
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.002 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0011 0.0001 0.0001
Trichomonas vaginalis Hexuronate transporter, putative 0.0013 0.0003 0.007
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0027 0.0012 0.0012
Leishmania major hypothetical protein, conserved in leishmania 0.0013 0.0003 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0007 0.0005
Echinococcus granulosus sex peptide receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Trichomonas vaginalis sugar transporter, putative 0.0013 0.0003 0.007
Toxoplasma gondii hypothetical protein 0.0013 0.0003 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Echinococcus multilocularis major facilitator superfamily domain containing protein 0.0013 0.0003 0.0003
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Echinococcus granulosus dna polymerase kappa 0.0019 0.0007 0.0007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0007 0.2216
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Echinococcus multilocularis synaptic vesicle 2 protein 0.0013 0.0003 0.0003
Schistosoma mansoni amine GPCR 0.0038 0.002 0.002
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.002 0.002
Echinococcus granulosus g protein coupled receptor 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.07
Schistosoma mansoni drug transporter 0.0013 0.0003 0.0003
Trypanosoma cruzi major facilitator superfamily, putative 0.0013 0.0003 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Trypanosoma brucei transporter, putative 0.0013 0.0003 0.0001
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.002 0.002
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Trypanosoma brucei unspecified product 0.0013 0.0003 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Schistosoma mansoni DNA polymerase eta 0.0019 0.0007 0.0007
Echinococcus granulosus sodium:glucose cotransporter 2 0.104 0.0709 0.0709
Echinococcus granulosus solute carrier family 5 0.104 0.0709 0.0709
Plasmodium falciparum amino acid transporter, putative 0.0027 0.0012 0.3941
Schistosoma mansoni myosin xvIII 0.0038 0.002 0.002
Schistosoma mansoni ap endonuclease 0.0019 0.0007 0.0007
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Echinococcus multilocularis fmrfamide receptor 0.0038 0.002 0.002
Loa Loa (eye worm) serotonin transporter b 0.0158 0.0103 0.0103
Toxoplasma gondii transporter, major facilitator family protein 0.0013 0.0003 0.0174
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.002 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0018 0.0018
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0007 1
Echinococcus granulosus neuropeptide receptor 0.0038 0.002 0.002
Loa Loa (eye worm) solute carrier family 6 member 4 0.0158 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0005
Toxoplasma gondii exonuclease III APE 0.0019 0.0007 0.0394
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Loa Loa (eye worm) glutathione reductase 0.0054 0.0031 0.0031
Schistosoma mansoni selectively expressed in embryonic epithelia protein-1 0.0013 0.0003 0.0003
Onchocerca volvulus Putative transporter 0.0013 0.0003 0.0002
Schistosoma mansoni sodium/chloride dependent transporter 0.0158 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.002 0.002
Onchocerca volvulus 0.0038 0.002 0.0019
Onchocerca volvulus 0.0013 0.0003 0.0002
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0027 0.0012 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.002 0.002
Plasmodium falciparum monocarboxylate transporter, putative 0.0013 0.0003 0.0978
Echinococcus multilocularis neuropeptide receptor A26 0.0038 0.002 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.002 0.002
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0011 0.0001 0.0001
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.002 0.002
Schistosoma mansoni neuropeptide receptor 0.0038 0.002 0.002
Onchocerca volvulus 0.0038 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0007 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0003 0.007
Schistosoma mansoni nAChR subunit 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Echinococcus granulosus Glycerol 3 phosphate transporter 0.0013 0.0003 0.0003
Brugia malayi GH02984p 0.0265 0.0176 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.002 0.002
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.0158 0.0158
Onchocerca volvulus 0.0013 0.0003 0.0002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0001 0.0001
Schistosoma mansoni sugar transporter 0.0013 0.0003 0.0003
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0011 0.0001 0.0001
Leishmania major transporter, putative,major facilitator superfamily protein (MFS), putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus sugar phosphate exchanger 3 0.0013 0.0003 0.0003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0011 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0007 1
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Loa Loa (eye worm) LGC-31 protein 0.0011 0.0001 0.0001
Entamoeba histolytica major facilitator superfamily transporter, putative 0.0013 0.0003 0.2304
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.002 0.002
Toxoplasma gondii zinc finger protein 36 family 3 protein 0.0013 0.0003 0.0174
Schistosoma mansoni oxalate:formate antiporter 0.0013 0.0003 0.0003
Schistosoma mansoni monocarboxylate transporter 0.0013 0.0003 0.0003
Entamoeba histolytica transporter, major facilitator family 0.0013 0.0003 0.2304
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0004 0.0215
Trichomonas vaginalis set domain proteins, putative 0.0273 0.0181 1
Brugia malayi Serotonin receptor 0.0038 0.002 0.002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3269 0.224 0.224
Loa Loa (eye worm) hypothetical protein 0.0265 0.0176 0.0176
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0003 0.0001
Echinococcus granulosus solute carrier family 43 0.0013 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0007 0.9531
Schistosoma mansoni opsin-like receptor 0.0038 0.002 0.002
Giardia lamblia Hypothetical protein 0.0013 0.0003 0.4205
Onchocerca volvulus 0.0013 0.0003 0.0002
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0027 0.0027
Brugia malayi Major Facilitator Superfamily protein 0.0013 0.0003 0.0003
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0007 0.0389
Giardia lamblia DINP protein human, muc B family 0.0019 0.0007 1
Trypanosoma brucei drug resistence protein, putative 0.0013 0.0003 0.0001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.0012 0.0012
Entamoeba histolytica major facilitator superfamily protein 0.0013 0.0003 0.2304
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.002 0.002
Echinococcus granulosus MFS transporter ceroid lipofuscinosis neuronal 0.0013 0.0003 0.0003
Echinococcus granulosus nAChR subunit 0.0011 0.0001 0.0001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.0012 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0007 0.0005
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.002 0.002
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0054 0.0031 0.3296
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0007 0.1343

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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