Detailed information for compound 266456

Basic information

Technical information
  • TDR Targets ID: 266456
  • Name: 4-chloro-2-[(2-fluorophenyl)carbamoylamino]be nzoic acid
  • MW: 308.692 | Formula: C14H10ClFN2O3
  • H donors: 3 H acceptors: 3 LogP: 3.29 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cc(Cl)ccc1C(=O)O)Nc1ccccc1F
  • InChi: 1S/C14H10ClFN2O3/c15-8-5-6-9(13(19)20)12(7-8)18-14(21)17-11-4-2-1-3-10(11)16/h1-7H,(H,19,20)(H2,17,18,21)
  • InChiKey: ULRPSUUXJOSUHQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-chloro-2-[[(2-fluoroanilino)-oxomethyl]amino]benzoic acid
  • 4-chloro-2-[[[(2-fluorophenyl)amino]-oxomethyl]amino]benzoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tar DNA binding protein 0.0063 0.0522 0.0522
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0006 0.0017 0.0017
Brugia malayi nuclear hormone receptor 0.001 0.0049 0.0083
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0017 0.011 0.0097
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0023 0.0163 0.0163
Entamoeba histolytica phosphoglycerate kinase, putative 0.0109 0.0923 0.101
Leishmania major DNA polymerase kappa, putative 0.0052 0.0418 0.2393
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0047 0.038 0.038
Brugia malayi hypothetical protein 0.0005 0.0006 0.0011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Entamoeba histolytica diacylglycerol kinase, putative 0.0039 0.0308 0.032
Echinococcus multilocularis neuropeptide Y receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Echinococcus granulosus orexin receptor type 2 0.0006 0.0017 0.0017
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0127 0.1293
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Leishmania major tyrosine specific protein phosphatase, putative 0.0017 0.011 0.0525
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0039 0.0308 0.0308
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0006 0.0017 0.0017
Echinococcus granulosus phosphoglycerate kinase 1 0.0109 0.0923 0.0923
Schistosoma mansoni adenoreceptor 0.0006 0.0017 0.0017
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0019 0.0125 0.1131
Echinococcus multilocularis neuropeptide FF receptor 2 0.0006 0.0017 0.0017
Leishmania major DNA polymerase eta, putative 0.0064 0.0525 0.3042
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0091 0.0769 0.4526
Loa Loa (eye worm) ceramide kinase 0.0039 0.0308 0.0345
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0093 0.0424
Leishmania major hypothetical protein, conserved 0.0039 0.0308 0.173
Echinococcus granulosus neuropeptides capa receptor 0.0006 0.0017 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0049 0.0049
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0017 0.011 0.0097
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0017 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0252 0.0282
Treponema pallidum phosphoglycerate kinase 0.0109 0.0923 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0042 0.0333 0.0347
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0063 0.0517 0.0554
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0049 0.0083
Onchocerca volvulus 0.0006 0.0017 0.0336
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0006 0.0009 0.0015
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0047 0.038 0.0426
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0522 0.0522
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0256 0.0286
Schistosoma mansoni amine GPCR 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0055
Echinococcus granulosus voltage dependent calcium channel 0.0013 0.0073 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0224 0.2227
Echinococcus multilocularis rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Trypanosoma cruzi DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Schistosoma mansoni nuclear hormone receptor 0.001 0.0049 0.0049
Echinococcus granulosus 7tm_1 domain containing protein 0.0006 0.0017 0.0017
Brugia malayi larval opioid receptor 0.0006 0.0017 0.0028
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0007
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0012 0.0065 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0049 0.0083
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0525 0.3042
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0017 0.011 0.0188
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0249 0.0253
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0049 0.0985
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0053 0.0428 0.0428
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0304 0.0304
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0005 0.0001 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0333 0.1879
Echinococcus granulosus sex peptide receptor 0.0006 0.0017 0.0017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0006 0.0009 0.0009
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0049 0.0049
Brugia malayi Tachykinin-like peptides receptor 99D 0.0006 0.0017 0.0028
Schistosoma mansoni survival motor neuron protein 0.0031 0.0232 0.0232
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0049 0.0055
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0049 0.0049
Echinococcus multilocularis serotonin receptor 0.0006 0.0017 0.0017
Leishmania major mitochondrial DNA polymerase beta 0.0193 0.167 1
Trichomonas vaginalis bmru protein, putative 0.0039 0.0308 0.3165
Schistosoma mansoni thyroid hormone receptor 0.001 0.0049 0.0049
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0047 0.038 0.038
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0001 0.0001
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0109 0.0923 1
Brugia malayi neuropeptide F receptor 0.0006 0.0017 0.0028
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0017 0.011 0.011
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0061 0.0503 0.0503
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0017 0.011 0.0525
Mycobacterium ulcerans DNA polymerase IV 0.0064 0.0531 0.0532
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Leishmania major diacylglycerol kinase-like protein 0.0039 0.0308 0.173
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0017 0.011 0.011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Onchocerca volvulus 0.0031 0.0232 0.4699
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0017 0.011 0.011
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0017 0.011 0.0188
Schistosoma mansoni hypothetical protein 0.0053 0.0428 0.0428
Trichomonas vaginalis DNA polymerase eta, putative 0.0064 0.0531 0.5638
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0061 0.0503 0.0503
Onchocerca volvulus 0.0017 0.011 0.2225
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0091 0.0769 0.4526
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Brugia malayi G protein-coupled receptor 0.0006 0.0017 0.0028
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.02 0.1069
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0017 0.011 0.2225
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0053 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0001 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0522 0.0522
Loa Loa (eye worm) hypothetical protein 0.0032 0.024 0.0269
Plasmodium vivax phosphoglycerate kinase, putative 0.0109 0.0923 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0012 0.0065 0.0065
Toxoplasma gondii phosphofructokinase PFKII 0.0019 0.0125 0.1274
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.0006 0.0007
Entamoeba histolytica phosphofructokinase, putative 0.0069 0.0575 0.0619
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Entamoeba histolytica hypothetical protein 0.0023 0.0163 0.0156
Echinococcus granulosus neuropeptides capa receptor 0.0006 0.0017 0.0017
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0005 0.0001 0.0001
Brugia malayi sulfakinin receptor protein 0.0006 0.0017 0.0028
Brugia malayi CXXC zinc finger family protein 0.0018 0.0122 0.0208
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0176 0.152 0.152
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0006 0.0017 0.0028
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0006 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0017 0.011 0.2225
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0006 0.0017 0.0017
Schistosoma mansoni DNA polymerase IV / kappa 0.0015 0.009 0.009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Toxoplasma gondii transporter, cation channel family protein 0.0013 0.0073 0.0701
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Trichomonas vaginalis phosphofructokinase, putative 0.0019 0.0125 0.1131
Brugia malayi hypothetical protein 0.0017 0.011 0.0188
Entamoeba histolytica diacylglycerol kinase, putative 0.0039 0.0308 0.032
Schistosoma mansoni apoptosis regulator bax 0.0053 0.0428 0.0428
Schistosoma mansoni opsin-like receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0005 0.0001 0.0001
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.004 0.0313 0.1757
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0049 0.0083
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.038 0.0368
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0011 0.0055 0.0062
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0066
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Echinococcus granulosus rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0012 0.0065 0.0255
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0039 0.0308 0.3165
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.024 0.1317
Trichomonas vaginalis rotamase, putative 0.0033 0.0256 0.258
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0017 0.011 0.2225
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0039 0.0308 0.3165
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0006 0.0017 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.0023 0.0163 0.0163
Brugia malayi 6-phosphofructokinase 0.0069 0.0575 0.0983
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.006 0.0494 0.0553
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0001 0.0001
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0017 0.011 0.0123
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0042 0.0333 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0494 0.5231
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0049 0.0049
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0017 0.011 0.011
Schistosoma mansoni sphingoid long chain base kinase 0.101 0.893 0.893
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0522 0.0522
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0039 0.0308 0.3165
Brugia malayi tailless protein 0.0005 0.0001 0.0002
Loa Loa (eye worm) diacylglycerol kinase 2 0.0039 0.0308 0.0345
Brugia malayi hypothetical protein 0.0017 0.011 0.0188
Echinococcus multilocularis survival motor neuron protein 1 0.0151 0.1299 0.1299
Echinococcus granulosus cpg binding protein 0.0019 0.0131 0.0131
Echinococcus multilocularis neuropeptide receptor 0.0006 0.0017 0.0017
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0049 0.0985
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0064 0.0525 0.0587
Plasmodium vivax 6-phosphofructokinase, putative 0.0019 0.0125 0.0959
Brugia malayi hypothetical protein 0.0005 0.0006 0.0011
Onchocerca volvulus 0.0006 0.0017 0.0336
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0006 0.0017 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0198 0.1943
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0055
Onchocerca volvulus 0.0006 0.0017 0.0336
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Toxoplasma gondii hypothetical protein 0.0011 0.0059 0.0551
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0006 0.0017 0.0017
Echinococcus granulosus Protein patched homolog 1 0.0027 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.0525 0.0897
Brugia malayi diacylglycerol kinase 0.0039 0.0308 0.0527
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0066
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0365 0.0365
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0037 0.029 0.1619
Brugia malayi RE15519p 0.0006 0.0017 0.0028
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0042 0.0333 0.0333
Schistosoma mansoni amine GPCR 0.0006 0.0017 0.0017
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0091 0.0769 0.4526
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0093 0.0044
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0015 0.0093 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0287 0.1599
Trichomonas vaginalis DNA helicase recq1, putative 0.0014 0.008 0.0626
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0017 0.011 0.011
Entamoeba histolytica deoxycytidyl transferase, putative 0.0047 0.038 0.04
Brugia malayi Serotonin receptor 0.0006 0.0017 0.0028
Echinococcus granulosus Diacylglycerol kinase theta 0.0039 0.0308 0.0308
Echinococcus granulosus biogenic amine 5HT receptor 0.0006 0.0017 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0012 0.0065 0.0466
Echinococcus granulosus tachykinin peptides receptor 99D 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0017 0.011 0.2225
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Echinococcus multilocularis g-protein coupled receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0006 0.0017 0.0017
Echinococcus granulosus sterol regulatory element binding protein 0.0027 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Onchocerca volvulus 0.0017 0.011 0.2225
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0109 0.0923 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0061 0.0503 0.0503
Trichomonas vaginalis phosphofructokinase, putative 0.0019 0.0125 0.1131
Schistosoma mansoni 6-phosphofructokinase 0.0069 0.0575 0.0575
Plasmodium falciparum diacylglycerol kinase, putative 0.0039 0.0308 0.3275
Onchocerca volvulus 0.0017 0.011 0.2225
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0093 0.0038
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0308 0.3165
Brugia malayi hypothetical protein 0.0039 0.0308 0.0527
Loa Loa (eye worm) phosphofructokinase 0.0069 0.0575 0.0644
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.024 0.1317
Echinococcus granulosus nuclear receptor nhr 48 0.0005 0.0001 0.0001
Echinococcus granulosus FTZ F1 alpha 0.001 0.0049 0.0049
Schistosoma mansoni amyloid beta A4 protein related 0.0044 0.0348 0.0348
Schistosoma mansoni hypothetical protein 0.0031 0.0232 0.0232
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0006 0.0017 0.0017
Brugia malayi Dopamine receptor 0.0006 0.0017 0.0028
Plasmodium vivax DNA repair protein REV1, putative 0.0015 0.009 0.0555
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0012 0.0065 0.0616
Brugia malayi serine/threonine-protein kinase plk-2 0.006 0.0494 0.0845
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.009 0.0402
Trypanosoma brucei phosphoglycerate kinase 0.0109 0.0923 0.5464
Onchocerca volvulus 0.0006 0.0017 0.0336
Loa Loa (eye worm) hypothetical protein 0.0109 0.0923 0.1034
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0017 0.011 0.011
Brugia malayi nuclear receptor NHR-67 0.0005 0.0001 0.0002
Brugia malayi ecdysteroid receptor 0.001 0.0049 0.0083
Schistosoma mansoni kinase 0.0031 0.0231 0.0231
Brugia malayi Protein-tyrosine phosphatase 0.0017 0.011 0.0188
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0006 0.0009 0.0015
Echinococcus multilocularis neuropeptides capa receptor 0.0006 0.0017 0.0017
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0026 0.019 0.019
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0049 0.0156
Loa Loa (eye worm) hypothetical protein 0.0039 0.0308 0.0345
Mycobacterium tuberculosis Diacylglycerol kinase 0.0039 0.0308 0.0287
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0005 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0019 0.0125 0.1131
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Brugia malayi Protein-tyrosine phosphatase 1 0.0019 0.0125 0.0214
Onchocerca volvulus 0.0006 0.0017 0.0336
Onchocerca volvulus 0.0017 0.011 0.2225
Echinococcus multilocularis somatostatin receptor 0.0006 0.0017 0.0017
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0019 0.0125 0.0697
Trypanosoma brucei Sphingosine kinase 0.0039 0.0308 0.173
Brugia malayi 6-phosphofructokinase 0.0069 0.0575 0.0983
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0012 0.0065 0.062
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0005 0.0001 0.0002
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0333 0.1879
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0055
Schistosoma mansoni 6-phosphofructokinase 0.0069 0.0575 0.0575
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0049 0.0049
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.011 0.011
Trypanosoma brucei polo-like protein kinase 0.006 0.0494 0.2858
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Brugia malayi Dopamine receptor protein 1 0.0006 0.0017 0.0028
Schistosoma mansoni hypothetical protein 0.0006 0.0017 0.0017
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0015 0.0093 0.0038
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0061 0.0503 0.0503
Echinococcus multilocularis sodium channel protein 0.0026 0.019 0.019
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0017 0.011 0.011
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.0006 0.0006
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Brugia malayi hypothetical protein 0.0005 0.0001 0.0002
Brugia malayi G-protein coupled receptor 0.0006 0.0017 0.0028
Echinococcus multilocularis sphingosine kinase 1 0.101 0.893 0.893
Onchocerca volvulus 0.0006 0.0017 0.0336
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0001 0.0001
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0039 0.0308 0.0308
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0019 0.0125 0.1131
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0061 0.0503 0.0503
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0012 0.0065 0.0281
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0049 0.0049
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0064 0.0531 0.5638
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.038 0.3332 0.3731
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0522 0.0522
Entamoeba histolytica hypothetical protein 0.0023 0.0163 0.0156
Schistosoma mansoni amine GPCR 0.0006 0.0017 0.0017
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0069 0.0575 0.3348
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0176 0.152 0.2598
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0006 0.0017 0.0028
Trypanosoma cruzi diacylglycerol kinase, putative 0.0039 0.0308 0.173
Trypanosoma brucei unspecified product 0.006 0.0493 0.2854
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0049 0.0985
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0049 0.0055
Onchocerca volvulus 0.0017 0.011 0.2225
Brugia malayi Bloom's syndrome protein homolog 0.0014 0.008 0.0136
Toxoplasma gondii hypothetical protein 0.0031 0.0235 0.2473
Trypanosoma brucei phosphoglycerate kinase 0.004 0.0313 0.1757
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0049 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0287 0.1599
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Schistosoma mansoni diacylglycerol kinase theta 0.0039 0.0308 0.0308
Echinococcus granulosus serine:threonine protein kinase PLK1 0.006 0.0494 0.0494
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0663 0.585 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Loa Loa (eye worm) latrophilin receptor protein 2 0.0176 0.152 0.1702
Brugia malayi ORL1-like opioid receptor 0.0006 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Onchocerca volvulus 0.0017 0.011 0.2225
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.0006 0.0017 0.0017
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0061 0.0503 0.0861
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Giardia lamblia DINP protein human, muc B family 0.0052 0.0418 0.4469
Mycobacterium ulcerans hypothetical protein 0.101 0.893 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0049 0.0083
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0006 0.0017 0.0017
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0049 0.0049
Entamoeba histolytica phosphofructokinase, putative 0.0069 0.0575 0.0619
Trypanosoma cruzi DNA damage repair protein, putative 0.0015 0.009 0.0402
Echinococcus multilocularis ceramide kinase 0.0039 0.0308 0.0308
Trichomonas vaginalis sphingosine kinase, putative 0.0039 0.0308 0.3165
Echinococcus granulosus 7TM GPCR rhodopsin 0.0006 0.0017 0.0017
Plasmodium falciparum DNA repair protein REV1, putative 0.0015 0.009 0.0884
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0027 0.02 0.1069
Toxoplasma gondii diacylglycerol kinase, putative 0.0039 0.0308 0.3275
Brugia malayi ImpB/MucB/SamB family protein 0.0047 0.038 0.065
Trypanosoma cruzi phosphoglycerate kinase, putative 0.004 0.0313 0.1757
Schistosoma mansoni neuropeptide f receptor 76f 0.0006 0.0017 0.0017
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.004 0.0313 0.1757
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0249 0.2623
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.011 0.011
Brugia malayi nuclear hormone receptor family member odr-7 0.0005 0.0001 0.0002
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0151 0.1299 0.1454
Schistosoma mansoni cpg binding protein 0.0019 0.0131 0.0131
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0224 0.2227
Echinococcus multilocularis allatostatin A receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0053 0.0428 0.0479
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0012 0.0065 0.0047
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0093 0.0038
Schistosoma mansoni DNA helicase recq1 0.0006 0.0009 0.0009
Schistosoma mansoni sphingosine kinase A B 0.101 0.893 0.893
Trichomonas vaginalis phosphofructokinase, putative 0.0019 0.0125 0.1131
Brugia malayi AKH receptor 0.0006 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Echinococcus multilocularis Niemann Pick C1 protein 0.0063 0.0517 0.0517
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Entamoeba histolytica diacylglycerol kinase, putative 0.0039 0.0308 0.032
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0039 0.0308 0.0308
Onchocerca volvulus 0.0017 0.011 0.2225
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0012 0.0065 0.0187
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0102 0.086 0.0903
Loa Loa (eye worm) apoptosis regulator protein 0.0053 0.0428 0.0479
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0176 0.152 0.152
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0017 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Echinococcus granulosus Nuclear hormone receptor HR96 0.0005 0.0001 0.0001
Echinococcus granulosus g protein coupled receptor 0.0006 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0026 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0049 0.0049
Echinococcus multilocularis expressed conserved protein 0.0059 0.0483 0.0483
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0061 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0055
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0055
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0249 0.1367
Echinococcus granulosus rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Mycobacterium ulcerans hypothetical protein 0.0015 0.0093 0.0038
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0006 0.0017 0.0028
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0494 0.5231
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0005 0.0001 0.0001
Echinococcus granulosus somatostatin receptor 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0017 0.011 0.2225
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0005 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0049 0.0055
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Onchocerca volvulus 0.0039 0.0308 0.6239
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0006 0.0017 0.0017
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.006 0.0494 0.2858
Entamoeba histolytica hypothetical protein, conserved 0.101 0.893 1
Trichomonas vaginalis rotamase, putative 0.0033 0.0249 0.2502
Onchocerca volvulus 0.0006 0.0017 0.0336
Echinococcus granulosus GPCR family 2 0.0176 0.152 0.152
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Echinococcus granulosus g protein coupled receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0052 0.0418 0.041
Schistosoma mansoni neuropeptide receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.011 0.011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Schistosoma mansoni hypothetical protein 0.0006 0.0017 0.0017
Schistosoma mansoni neuropeptide receptor 0.0006 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0119 0.1017 0.1017
Loa Loa (eye worm) hypothetical protein 0.0027 0.0198 0.0222
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Plasmodium falciparum acyl-CoA synthetase 0.0011 0.0059 0.0552
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0019 0.0125 0.1274
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Brugia malayi Latrophilin receptor protein 2 0.0176 0.152 0.2598
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0065 0.0255
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0049 0.0049
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0015 0.0093 0.0038
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Brugia malayi phosphofructokinase 0.0069 0.0575 0.0983
Schistosoma mansoni phosphoglycerate kinase 0.0109 0.0923 0.0923
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0006 0.0017 0.0017
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0006 0.0017 0.0017
Brugia malayi Phosphoglycerate kinase 0.004 0.0313 0.0535
Echinococcus multilocularis sterol regulatory element binding protein 0.0027 0.0198 0.0198
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0049 0.0055
Brugia malayi diacylglycerol kinase 0.0039 0.0308 0.0527
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0017 0.011 0.0525
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0249 0.1367
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0006 0.0017 0.0017
Trichomonas vaginalis bmru protein, putative 0.0039 0.0308 0.3165
Loa Loa (eye worm) hypothetical protein 0.0039 0.0308 0.0345
Schistosoma mansoni nuclear receptor 0.0005 0.0001 0.0001
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0017 0.011 0.0123
Echinococcus granulosus dnaJ subfamily B 0.0261 0.2277 0.2277
Echinococcus granulosus survival motor neuron protein 1 0.0151 0.1299 0.1299
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0049 0.0083
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Schistosoma mansoni pcd6 interacting protein-related 0.0017 0.011 0.011
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0494 0.5231
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0012 0.0065 0.0065
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0017 0.011 0.011
Echinococcus multilocularis voltage dependent calcium channel 0.0061 0.0503 0.0503
Giardia lamblia Protein tyrosine phosphatase 0.0017 0.011 0.1106
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0006 0.0006
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0066
Trypanosoma brucei phosphoglycerate kinase 0.0109 0.0923 0.5464
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Echinococcus granulosus geminin 0.0119 0.1017 0.1017
Echinococcus granulosus neuropeptide receptor 0.0006 0.0017 0.0017
Echinococcus granulosus neuropeptide FF receptor 2 0.0006 0.0017 0.0017
Echinococcus multilocularis dnaJ subfamily B 0.0261 0.2277 0.2277
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0109 0.0923 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0284 0.2478 0.2478
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0006 0.0009 0.0009
Onchocerca volvulus 0.0017 0.011 0.2225
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0006 0.0017 0.0017
Leishmania major sphingosine kinase A, B, putative 0.0039 0.0308 0.173
Entamoeba histolytica phosphofructokinase, putative 0.0069 0.0575 0.0619
Trichomonas vaginalis phosphofructokinase, putative 0.0069 0.0575 0.6127
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0494 0.5231
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0037 0.029 0.1619
Trypanosoma cruzi DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0006 0.0009 0.0009
Loa Loa (eye worm) TYRA-2 protein 0.0006 0.0017 0.0019
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0012 0.0065 0.062
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0256 0.0437
Trypanosoma cruzi polo-like protein kinase, putative 0.006 0.0494 0.2858
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0039 0.0308 0.173
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0093 0.0159
Schistosoma mansoni DNA polymerase eta 0.0064 0.0525 0.0525
Brugia malayi polk-prov protein 0.0032 0.024 0.0411
Echinococcus multilocularis g protein coupled receptor 0.0006 0.0017 0.0017
Echinococcus granulosus neuropeptide receptor A26 0.0006 0.0017 0.0017
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0249 0.1367
Schistosoma mansoni alpha-1 adrenergic receptor 0.0006 0.0017 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0256 0.258
Plasmodium falciparum phosphoglycerate kinase 0.0109 0.0923 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0019 0.0125 0.1274
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Echinococcus granulosus neuropeptide s receptor 0.0006 0.0017 0.0017
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0069 0.0575 0.0587
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Brugia malayi GnHR receptor homolog 0.0006 0.0017 0.0028
Loa Loa (eye worm) hypothetical protein 0.0061 0.0503 0.0564
Trypanosoma brucei DNA damage repair protein, putative 0.0015 0.009 0.0402
Brugia malayi Serotonin receptor 0.0006 0.0017 0.0028
Loa Loa (eye worm) neuropeptide F receptor 0.0006 0.0017 0.0019
Chlamydia trachomatis phosphoglycerate kinase 0.0109 0.0923 1
Schistosoma mansoni coup transcription factor 0.001 0.0049 0.0049
Trypanosoma brucei unspecified product 0.0033 0.0249 0.1372
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0494 0.5231
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0049 0.0055
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0055
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0019 0.0125 0.0125
Brugia malayi nuclear receptor NHR-88 0.001 0.0049 0.0083
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.009 0.0402
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Schistosoma mansoni hypothetical protein 0.0119 0.1017 0.1017
Onchocerca volvulus 0.0006 0.0017 0.0336
Brugia malayi F/Y-rich N-terminus family protein 0.0006 0.0009 0.0015
Brugia malayi Calcitonin receptor-like protein seb-1 0.0556 0.4893 0.8363
Leishmania major phosphoglycerate kinase C, glycosomal 0.0109 0.0923 0.5464
Schistosoma mansoni hypothetical protein 0.0053 0.0428 0.0428
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0049 0.0055
Trichomonas vaginalis sphingosine kinase, putative 0.0039 0.0308 0.3165
Brugia malayi hypothetical protein 0.0151 0.1299 0.222
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0017 0.011 0.0097
Brugia malayi steroid hormone receptor 0.001 0.0049 0.0083
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0006 0.0017 0.0336
Toxoplasma gondii 6-phosphofructokinase 0.0019 0.0125 0.1274
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0017 0.011 0.0525
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.004 0.0338
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0522 0.0892
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0019 0.0125 0.014
Echinococcus multilocularis dna polymerase eta 0.0064 0.0525 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0049 0.0083
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0005 0.0001 0.0001
Echinococcus granulosus alpha 1A adrenergic receptor 0.0006 0.0017 0.0017
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0017 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0261 0.2277 0.2277
Brugia malayi Diacylglycerol kinase protein 2 0.0039 0.0308 0.0527
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.009 0.0402
Plasmodium vivax 6-phosphofructokinase, putative 0.0019 0.0125 0.0959
Schistosoma mansoni hypothetical protein 0.0176 0.152 0.152
Brugia malayi putative neuropeptide receptor 0.0006 0.0017 0.0028
Schistosoma mansoni amine GPCR 0.0006 0.0017 0.0017
Echinococcus multilocularis G-protein coupled receptor, putative 0.0006 0.0017 0.0017
Echinococcus multilocularis 6 phosphofructokinase 0.0069 0.0575 0.0575
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Brugia malayi G-protein coupled receptor 0.0006 0.0017 0.0028
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0054 0.0054
Onchocerca volvulus 0.0017 0.011 0.2225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Onchocerca volvulus Neuropeptide F receptor homolog 0.0006 0.0017 0.0336
Echinococcus multilocularis nuclear receptor nhr 48 0.0005 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0006 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0049 0.0083
Giardia lamblia Kinase, PLK 0.006 0.0494 0.5307
Onchocerca volvulus 0.0005 0.0001 0.0026
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.011 0.011
Echinococcus granulosus amyloid beta A4 protein 0.0044 0.0348 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Trypanosoma cruzi DNA damage repair protein, putative 0.0015 0.009 0.0402
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0093 0.0159
Schistosoma mansoni DNA helicase recq5 0.0006 0.0009 0.0009
Plasmodium vivax diacylglycerol kinase, putative 0.0039 0.0308 0.3033
Schistosoma mansoni nuclear receptor nhr-48 0.0005 0.0001 0.0001
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0019 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0063 0.0517 0.0579
Brugia malayi latrophilin 2 splice variant baaae 0.038 0.3332 0.5695
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Trypanosoma cruzi polo-like protein kinase, putative 0.006 0.0494 0.2858
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0049 0.0083
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0365 0.0365
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Echinococcus granulosus dro:myosuppressin receptor 0.0006 0.0017 0.0017
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0093 0.0159
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0006 0.0006
Echinococcus granulosus Diacylglycerol kinase zeta 0.0039 0.0308 0.0308
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.011 0.011
Onchocerca volvulus 4.1 G protein, putative homolog 0.0017 0.011 0.2225
Entamoeba histolytica hypothetical protein 0.0023 0.0163 0.0156
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.011 0.011
Echinococcus granulosus 6 phosphofructokinase 0.0069 0.0575 0.0575
Onchocerca volvulus 0.0017 0.011 0.2225
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0042 0.0333 0.1879
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Onchocerca volvulus 0.0006 0.0017 0.0336
Echinococcus multilocularis neuropeptides capa receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0006 0.0017 0.0019
Echinococcus multilocularis sex peptide receptor 0.0006 0.0017 0.0017
Schistosoma mansoni thyroid hormone receptor 0.001 0.0049 0.0049
Loa Loa (eye worm) histone methyltransferase 0.0006 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0006 0.0017 0.0336
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0039 0.0308 0.0308
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0039 0.0308 0.0345
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0006 0.0017 0.0017
Trypanosoma cruzi Sphingosine kinase 0.0039 0.0308 0.173
Echinococcus multilocularis fmrfamide receptor 0.0006 0.0017 0.0017
Schistosoma mansoni cpg binding protein 0.0019 0.0131 0.0131
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Echinococcus multilocularis hypothetical protein 0.0017 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0093 0.0104
Schistosoma mansoni rotamase 0.0033 0.0256 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0049 0.0055
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0027 0.02 0.1069
Schistosoma mansoni histamine h1 receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0007
Trypanosoma brucei diacylglycerol kinase, putative 0.0039 0.0308 0.173
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0039 0.0308 0.3275
Brugia malayi hypothetical protein 0.0017 0.011 0.0188
Onchocerca volvulus 0.0018 0.0122 0.2462
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0061 0.0503 0.0503
Brugia malayi exodeoxyribonuclease III family protein 0.0012 0.0065 0.0112
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0047 0.038 0.038
Loa Loa (eye worm) melatonin receptor type 1A 0.0006 0.0017 0.0019
Echinococcus multilocularis GPCR, family 2 0.0176 0.152 0.152
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0109 0.0923 0.098
Schistosoma mansoni opsin-like receptor 0.0006 0.0017 0.0017
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0061 0.0503 0.0503
Echinococcus granulosus peptide allatostatin:somatostatin 0.0006 0.0017 0.0017
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0031 0.0232 0.0397
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Schistosoma mansoni biogenic amine (5HT) receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) G-protein coupled receptor 0.0006 0.0017 0.0019
Onchocerca volvulus 0.001 0.0049 0.0985
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0049 0.0083
Trypanosoma brucei DNA polymerase IV, putative 0.0064 0.0531 0.3081
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0049 0.0083
Onchocerca volvulus 0.0006 0.0017 0.0336
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0053 0.0428 0.0732
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0049 0.0083
Brugia malayi Eye-specific diacylglycerol kinase 0.0039 0.0308 0.0527
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0017 0.011 0.011
Trichomonas vaginalis phosphofructokinase, putative 0.0069 0.0575 0.6127
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0042 0.0333 0.0333
Echinococcus multilocularis rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Schistosoma mansoni ap endonuclease 0.0012 0.0065 0.0065
Brugia malayi nuclear receptor NHR-88 0.0005 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0006 0.0017 0.0017
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.0006 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0093 0.0424
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0053 0.0428 0.0428
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0017 0.011 0.011
Echinococcus multilocularis Diacylglycerol kinase theta 0.0039 0.0308 0.0308
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0005 0.0001 0.0026
Schistosoma mansoni hypothetical protein 0.0176 0.152 0.152
Onchocerca volvulus 0.0006 0.0017 0.0336
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0066
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0019 0.0125 0.0764
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0049 0.0049
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0006 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0494 0.5231
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis fmrfamide receptor 0.0006 0.0017 0.0017
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0109 0.0923 1
Echinococcus multilocularis G protein coupled receptor 139 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0234 0.1278
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0039 0.0308 0.173
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0039 0.0307 0.0525
Giardia lamblia Phosphoglycerate kinase 0.0109 0.0923 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0006 0.0017 0.0017
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0019 0.0125 0.1274
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0365 0.0409
Brugia malayi nuclear receptor RXR 0.0005 0.0001 0.0002
Loa Loa (eye worm) voltage-dependent calcium channel 0.0013 0.0073 0.0082
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0193 0.167 1
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0049 0.0156
Schistosoma mansoni diacylglycerol kinase theta 0.0039 0.0308 0.0308
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Echinococcus multilocularis Niemann Pick C1 protein 0.009 0.0756 0.0756
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0365 0.0365
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0006 0.0009 0.0009
Echinococcus multilocularis voltage dependent calcium channel 0.0061 0.0503 0.0503
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0049 0.0441
Echinococcus granulosus rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Echinococcus granulosus expressed protein 0.0033 0.0256 0.0256
Mycobacterium ulcerans hypothetical protein 0.0015 0.009 0.0034
Brugia malayi CHE-14 protein 0.0027 0.0198 0.0339
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0012 0.0065 0.0007
Trypanosoma brucei protein tyrosine phosphatase 1 0.0017 0.011 0.0525
Schistosoma mansoni growth hormone secretagogue receptor 0.0006 0.0017 0.0017
Echinococcus granulosus transcription factor Dp 1 0.0024 0.0175 0.0175
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0049 0.0049
Toxoplasma gondii exonuclease III APE 0.0012 0.0065 0.062
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0012 0.0065 0.0013
Brugia malayi hypothetical protein 0.0017 0.011 0.0188
Leishmania major ATP-dependent phosphofructokinase 0.0069 0.0575 0.3348
Leishmania major hypothetical protein, conserved 0.0039 0.0308 0.173
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Onchocerca volvulus 0.0017 0.011 0.2225
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Mycobacterium ulcerans phosphoglycerate kinase 0.0109 0.0923 0.0974
Brugia malayi nuclear receptor RXR 0.0005 0.0006 0.0011
Loa Loa (eye worm) DR-78 0.0005 0.0001 0.0001
Entamoeba histolytica acyl-coA synthetase, putative 0.0015 0.0093 0.0078
Echinococcus granulosus ceramide kinase 0.0039 0.0308 0.0308
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0193 0.167 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0.0093 0.0078
Brugia malayi Ceramide kinase 0.0039 0.0308 0.0527
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0049 0.0049
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0522 0.0522
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0006 0.0011
Echinococcus granulosus tm gpcr rhodopsin 0.0006 0.0017 0.0017
Trichomonas vaginalis diacylglycerol kinase, putative 0.0039 0.0308 0.3165
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0019 0.0125 0.0764
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0069 0.0575 0.5802
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0006 0.0011
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0006 0.0017 0.0019
Schistosoma mansoni hypothetical protein 0.0053 0.0428 0.0428
Brugia malayi RNA binding protein 0.0063 0.0522 0.0892
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0049 0.0156
Entamoeba histolytica diacylglycerol kinase, putative 0.0039 0.0308 0.032
Trypanosoma brucei DNA polymerase IV, putative 0.0064 0.0531 0.3081
Entamoeba histolytica hypothetical protein 0.0023 0.0163 0.0156
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0019 0.0125 0.0114
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0006 0.0017 0.0019
Trichomonas vaginalis ap endonuclease, putative 0.0012 0.0065 0.0466
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Echinococcus granulosus dna polymerase eta 0.0064 0.0525 0.0525
Echinococcus granulosus G protein coupled receptor 139 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0093 0.0104
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Onchocerca volvulus 0.0006 0.0017 0.0336
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Echinococcus multilocularis microtubule associated protein 2 0.1131 1 1
Onchocerca volvulus Ceramide kinase 1 homolog 0.0039 0.0308 0.6239
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0049 0.0055
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0333 0.1879
Onchocerca volvulus 0.0017 0.011 0.2225
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0006 0.0017 0.0017
Echinococcus granulosus g protein coupled receptor 0.0006 0.0017 0.0017
Brugia malayi putative neuropeptide receptor NPR1 0.0006 0.0017 0.0028
Brugia malayi hypothetical protein 0.0005 0.0001 0.0002
Trypanosoma brucei chrX additional, unordered contigs 0.0015 0.009 0.0402
Mycobacterium ulcerans diacylglycerol kinase 0.0039 0.0308 0.0281
Schistosoma mansoni zinc finger protein 0.0005 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Trypanosoma brucei DNA polymerase eta, putative 0.0064 0.0525 0.3042
Loa Loa (eye worm) X11 protein 0.0044 0.0348 0.039
Leishmania major DNA polymerase kappa, putative 0.0015 0.009 0.0402
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.008 0.0626
Echinococcus granulosus biogenic amine 5HT receptor 0.0006 0.0017 0.0017
Onchocerca volvulus Serine\/threonine kinase homolog 0.006 0.0494 1
Onchocerca volvulus 0.0017 0.011 0.2225
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0049 0.0083
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0017 0.0017
Loa Loa (eye worm) neuropeptide F receptor 0.0006 0.0017 0.0019
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0011 0.0059 0.0006
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0006 0.0017 0.0336
Trichomonas vaginalis phosphofructokinase, putative 0.0019 0.0125 0.1131
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0006 0.0017 0.0017
Trichomonas vaginalis diacylglycerol kinase, putative 0.0039 0.0308 0.3165
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0287 0.1599
Loa Loa (eye worm) RNA binding protein 0.0063 0.0522 0.0584
Echinococcus multilocularis expressed protein 0.0033 0.0256 0.0256
Schistosoma mansoni amine GPCR 0.0006 0.0017 0.0017
Echinococcus granulosus voltage dependent calcium channel 0.0061 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0066
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0049 0.0049
Brugia malayi hypothetical protein 0.0042 0.0333 0.0569
Echinococcus multilocularis serotonin receptor 0.0006 0.0017 0.0017
Echinococcus granulosus protein tyrosine phosphatase n9 0.0017 0.011 0.011
Echinococcus granulosus Niemann Pick C1 protein 0.009 0.0756 0.0756
Schistosoma mansoni phosphoglycerate kinase 0.0109 0.0923 0.0923
Toxoplasma gondii histone lysine methyltransferase SET1 0.0035 0.0267 0.2826
Mycobacterium ulcerans DNA polymerase IV 0.0064 0.0531 0.0532
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0193 0.167 1
Leishmania major DNA damage repair protein, putative 0.0015 0.009 0.0402
Echinococcus multilocularis protein dispatched 1 0.0031 0.0232 0.0232
Echinococcus granulosus serotonin receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis transcription factor Dp 1 0.0024 0.0175 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Echinococcus granulosus fmrfamide receptor 0.0006 0.0017 0.0017
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0109 0.0923 1
Schistosoma mansoni voltage-gated cation channel 0.0061 0.0503 0.0503
Brugia malayi G protein-coupled receptor F59B2.13 0.0006 0.0017 0.0028
Brugia malayi conserved hypotetical protein 0.0005 0.0001 0.0002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0284 0.2478 0.2478
Loa Loa (eye worm) hypothetical protein 0.0015 0.0093 0.0104
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0012 0.0065 0.0073
Schistosoma mansoni patched 1 0.0027 0.0198 0.0198
Schistosoma mansoni hypothetical protein 0.0026 0.019 0.019
Brugia malayi Melatonin receptor type 1A 0.0006 0.0017 0.0028
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0017 0.011 0.011
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Schistosoma mansoni hypothetical protein 0.0039 0.0308 0.0308
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0517 0.4554 0.4554
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0049 0.0049
Echinococcus multilocularis neuropeptide Y receptor 0.0006 0.0017 0.0017
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0093 0.0424
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0109 0.0923 1
Leishmania major diacylglycerol kinase, putative 0.0039 0.0308 0.173
Echinococcus granulosus allatostatin A receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Echinococcus granulosus bloom syndrome protein 0.0014 0.008 0.008
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.009 0.0402
Echinococcus multilocularis geminin 0.0119 0.1017 0.1017
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0005 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0053 0.0428 0.0428
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0039 0.0308 0.173
Echinococcus multilocularis protein patched 0.0027 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0017 0.011 0.011
Echinococcus granulosus neuropeptide Y receptor 0.0006 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.038 0.3332 0.3332
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Brugia malayi TAR-binding protein 0.0063 0.0522 0.0892
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0663 0.585 0.6551
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0042 0.0333 0.0569
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0069 0.0575 0.5938
Onchocerca volvulus 0.0017 0.011 0.2225
Echinococcus multilocularis amyloid beta A4 protein 0.0044 0.0348 0.0348
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Echinococcus multilocularis orexin receptor type 2 0.0006 0.0017 0.0017
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0017 0.011 0.011
Schistosoma mansoni biogenic amine receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0522 0.0584
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0176 0.152 0.152
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0017 0.011 0.011
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0049 0.0083
Echinococcus multilocularis cpg binding protein 0.0019 0.0131 0.0131
Entamoeba histolytica serine/threonine protein kinase, putative 0.006 0.0494 0.0528
Trypanosoma brucei phosphoglycerate kinase, putative 0.004 0.0313 0.1757
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.011 0.0188
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0023 0.0163 0.0163
Brugia malayi Dopamine receptor protein 2 0.0006 0.0017 0.0028
Echinococcus multilocularis neuropeptide s receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0027 0.0198 0.0222
Schistosoma mansoni microtubule-associated protein tau 0.1131 1 1
Trypanosoma cruzi Sphingosine kinase 0.0039 0.0308 0.173
Brugia malayi Nuclear hormone receptor E75 0.0005 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Echinococcus granulosus hypothetical protein 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Echinococcus multilocularis g protein coupled receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.001 0.0049 0.0055
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Schistosoma mansoni neuropeptide receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.02 0.1069
Echinococcus multilocularis phosphoglycerate kinase 1 0.0109 0.0923 0.0923
Echinococcus multilocularis bloom syndrome protein 0.0014 0.008 0.008
Mycobacterium ulcerans 6-phosphofructokinase 0.0069 0.0575 0.0581
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0494 0.0494
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0039 0.0308 0.173
Echinococcus multilocularis dna polymerase kappa 0.0064 0.0531 0.0531
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0017 0.011 0.011
Brugia malayi nuclear hormone receptor family member nhr-6 0.0005 0.0001 0.0002
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0006 0.0009 0.0009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0012 0.0065 0.0255
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Echinococcus granulosus dna polymerase kappa 0.0064 0.0531 0.0531
Echinococcus multilocularis rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Trichomonas vaginalis pten, drome, putative 0.0017 0.011 0.0961
Echinococcus granulosus sphingosine kinase 1 0.101 0.893 0.893
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Brugia malayi neuropeptide F receptor 0.0006 0.0017 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0418 0.2393
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0006 0.0009 0.001
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0017 0.011 0.011
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0019 0.0125 0.1274
Echinococcus multilocularis rhodopsin orphan GPCR 0.0006 0.0017 0.0017
Plasmodium vivax diacylglycerol kinase, putative 0.0039 0.0308 0.3033
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.004 0.0313 0.1757
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0039 0.0308 0.0308
Plasmodium falciparum diacylglycerol kinase, putative 0.0039 0.0308 0.3275
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0015 0.009 0.0884
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Loa Loa (eye worm) protein tyrosine phosphatase 0.0017 0.011 0.0123
Schistosoma mansoni biogenic amine receptor 0.0006 0.0017 0.0017
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.011 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0308 0.173
Echinococcus multilocularis 0.0017 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0109 0.0923 0.5464
Echinococcus granulosus Niemann Pick C1 protein 0.0063 0.0517 0.0517
Brugia malayi Niemann-Pick C1 protein precursor 0.0063 0.0517 0.0883
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0049 0.0083
Schistosoma mansoni neuropeptide receptor 0.0006 0.0017 0.0017
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.006 0.0494 0.0494
Trypanosoma cruzi diacylglycerol kinase, putative 0.0039 0.0308 0.173
Trichomonas vaginalis phosphofructokinase, putative 0.0069 0.0575 0.6127
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Giardia lamblia DNA damage repair protein 0.0015 0.009 0.0884
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Leishmania major phosphoglycerate kinase B, cytosolic 0.0109 0.0923 0.5464
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0049 0.0049
Onchocerca volvulus 0.0006 0.0017 0.0336
Echinococcus multilocularis neuropeptide receptor A26 0.0006 0.0017 0.0017
Echinococcus granulosus neuropeptide Y receptor 0.0006 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0176 0.152 0.152
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0006 0.0017 0.0028
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.004 0.0313 0.1757
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0365 0.0365
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0017 0.011 0.011
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.011 0.011
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0017 0.011 0.011
Brugia malayi follicle stimulating hormone receptor 0.0006 0.0017 0.0028
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0017 0.011 0.011
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0052 0.0418 0.2393
Onchocerca volvulus 0.0017 0.011 0.2225
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0061 0.0503 0.0503
Schistosoma mansoni terminal deoxycytidyl transferase 0.0047 0.038 0.038
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0493 0.2854
Loa Loa (eye worm) hypothetical protein 0.0013 0.0073 0.0082
Echinococcus multilocularis g protein coupled receptor 0.0006 0.0017 0.0017
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0093 0.0038
Onchocerca volvulus 0.0005 0.0001 0.0026
Loa Loa (eye worm) nuclear receptor NHR-67 0.0005 0.0001 0.0001
Brugia malayi ecdysone receptor 0.0005 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0109 0.0923 0.5464
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0234 0.2462
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0017 0.011 0.0123
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0064 0.0525 0.0525
Loa Loa (eye worm) hypothetical protein 0.0039 0.0308 0.0345
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0005 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0365 0.0365
Schistosoma mansoni biogenic amine receptor 0.0006 0.0017 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0093 0.0038
Echinococcus granulosus neuropeptide receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0018 0.0122 0.0136
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0017 0.011 0.011
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.011 0.0123
Trichomonas vaginalis CAMK family protein kinase 0.006 0.0494 0.5231
Brugia malayi Protein-tyrosine phosphatase 0.0017 0.011 0.0188
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0006 0.0009 0.00000000024857
Loa Loa (eye worm) hypothetical protein 0.101 0.893 1
Mycobacterium tuberculosis Conserved protein 0.101 0.893 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0556 0.4893 0.5479
Trypanosoma brucei unspecified product 0.0033 0.0249 0.1372
Brugia malayi hypothetical protein 0.0023 0.0163 0.0278
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0385 0.3379 0.3379
Schistosoma mansoni hypothetical protein 0.0026 0.019 0.019
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0308 0.173
Schistosoma mansoni neuropeptide F-like receptor 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0015 0.0093 0.1887
Schistosoma mansoni myosin xvIII 0.0006 0.0017 0.0017
Loa Loa (eye worm) calcium channel 0.0061 0.0503 0.0564
Schistosoma mansoni hypothetical protein 0.0026 0.019 0.019
Echinococcus multilocularis neuropeptide receptor 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0017 0.011 0.2225
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0015 0.0093 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0053 0.0428 0.0428
Schistosoma mansoni ap endonuclease 0.0012 0.0065 0.0065
Brugia malayi hypothetical protein 0.0006 0.0017 0.0028
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0365 0.0624
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0006 0.0017 0.0017
Echinococcus granulosus g-protein coupled receptor 0.0006 0.0017 0.0017
Loa Loa (eye worm) RecQ helicase 0.0014 0.008 0.0089
Loa Loa (eye worm) 6-phosphofructokinase 0.0069 0.0575 0.0644
Schistosoma mansoni nuclear receptor 0.0005 0.0001 0.0001
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0017 0.011 0.011
Schistosoma mansoni opsin-like receptor 0.0006 0.0017 0.0017
Onchocerca volvulus 0.0017 0.011 0.2225
Trypanosoma cruzi DNA polymerase kappa, putative 0.0064 0.0531 0.3081
Schistosoma mansoni hypothetical protein 0.0023 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0176 0.152 0.1702
Echinococcus granulosus thyroid hormone receptor alpha 0.0005 0.0001 0.0001
Leishmania major DNA polymerase eta, putative 0.0031 0.0234 0.1278
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0049 0.0083
Loa Loa (eye worm) nuclear hormone receptor 0.0005 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Trichomonas vaginalis phosphofructokinase, putative 0.0069 0.0575 0.6127
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.0252 0.1389
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0522 0.0522
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0017 0.011 0.0525
Brugia malayi hypothetical protein 0.0017 0.011 0.0188
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0365 0.0365
Onchocerca volvulus 0.0006 0.0017 0.0336
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0522 0.0584
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0042 0.0333 0.0333
Loa Loa (eye worm) G-protein coupled receptor 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123
Loa Loa (eye worm) hypothetical protein 0.0005 0.0006 0.0007
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0017 0.011 0.011
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0049 0.0083
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0039 0.0308 0.3275
Schistosoma mansoni hypothetical protein 0.0006 0.0017 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.0006 0.0017 0.0017
Echinococcus multilocularis dro:myosuppressin receptor 0.0006 0.0017 0.0017
Echinococcus granulosus expressed conserved protein 0.0059 0.0483 0.0483
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0049 0.0049
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0049 0.0156
Loa Loa (eye worm) 6-phosphofructokinase 0.0069 0.0575 0.0644
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.011 0.011
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0006 0.0017 0.0019
Onchocerca volvulus 0.0017 0.011 0.2225
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0069 0.0575 0.3348
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0001
Trypanosoma brucei DNA damage repair protein, putative 0.0015 0.009 0.0402
Schistosoma mansoni cpg binding protein 0.0018 0.0122 0.0122
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0006 0.0017 0.0017
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0049 0.0049
Plasmodium vivax acyl-CoA synthetase, putative 0.0011 0.0059 0.0211
Brugia malayi nuclear hormone receptor 0.0005 0.0001 0.0002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0.0093 0.0078
Trypanosoma cruzi phosphoglycerate kinase, putative 0.004 0.0313 0.1757
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0249 0.1367
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0006 0.0017 0.0028
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0042 0.0333 0.0373
Loa Loa (eye worm) hypothetical protein 0.0011 0.0059 0.0066
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0049 0.0049
Brugia malayi orphan nuclear receptor NR2E1 0.0005 0.0001 0.0002
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0006 0.0017 0.0017
Brugia malayi Phosphoglycerate kinase 0.0109 0.0923 0.1578
Mycobacterium tuberculosis Conserved hypothetical protein 0.0102 0.086 0.0909
Loa Loa (eye worm) hypothetical protein 0.0017 0.011 0.0123

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 20 uM In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells. ChEMBL. 14667236
IC50 (binding) = 20 uM In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells. ChEMBL. 14667236

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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