Detailed information for compound 282258

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 221.209 | Formula: C11H11NO4
  • H donors: 1 H acceptors: 2 LogP: 1.56 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1C1OC(=O)NC1=O)C
  • InChi: 1S/C11H11NO4/c1-6-4-3-5-7(15-2)8(6)9-10(13)12-11(14)16-9/h3-5,9H,1-2H3,(H,12,13,14)
  • InChiKey: KKSLMDSQQBSFCC-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0041 0.0101 0.0269
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0022 0.0026 0.0034
Echinococcus multilocularis ecdysone induced protein 78C 0.0036 0.0083 0.0083
Brugia malayi jmjC domain containing protein 0.0126 0.0437 0.1214
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0034 0.0074 0.068
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0037 0.0096
Echinococcus multilocularis muscleblind protein 0.0311 0.117 0.117
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0022 0.0026 0.0086
Schistosoma mansoni jumonji domain containing protein 0.0123 0.0424 0.0749
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Mycobacterium tuberculosis Conserved protein 0.0037 0.0087 0.0237
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0115 0.0396 0.0396
Schistosoma mansoni hypothetical protein 0.0037 0.0087 0.0149
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0123 0.0424 0.0424
Entamoeba histolytica P-glyco protein 6, putative 0.0022 0.0026 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0036 0.0083 0.0218
Loa Loa (eye worm) fibroinase 0.0017 0.0008 0.001
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.077 0.2979 0.4679
Echinococcus granulosus geminin 0.0175 0.0632 0.1125
Schistosoma mansoni agrin 0.0079 0.0251 0.0441
Entamoeba histolytica P-glycoprotein 5, putative 0.0022 0.0026 0.0076
Schistosoma mansoni loxhd1 0.0041 0.0101 0.0174
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0091 0.0136
Echinococcus multilocularis expressed protein 0.0079 0.0251 0.0251
Echinococcus multilocularis caspase 8 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0245 0.0906 0.2518
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0008 0.0003
Onchocerca volvulus 0.0017 0.0008 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.2346 1
Leishmania major basic transcription factor 3a, putative 0.0036 0.0083 0.0123
Loa Loa (eye worm) hypothetical protein 0.0923 0.3586 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.2346 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.0437 0.1209
Onchocerca volvulus 0.0115 0.0396 0.1085
Trypanosoma brucei RNA helicase, putative 0.01 0.0336 0.0521
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Mycobacterium ulcerans hypothetical protein 0.0025 0.0037 0.0097
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Mycobacterium leprae Probable lipase LipE 0.0037 0.0087 0.0318
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0067 0.0607
Schistosoma mansoni nuclear hormone receptor 0.0036 0.0083 0.0142
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0087 0.0149
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0199 0.0199
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0037 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Schistosoma mansoni rab6-interacting 0.0041 0.0101 0.0174
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0087 0.0237
Schistosoma mansoni zinc finger protein 0.0017 0.0007 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0632 0.2696
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0127 0.0226
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0229 0.0843 0.1319
Schistosoma mansoni follistatin 0.0079 0.0251 0.0441
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0279 0.104 0.1629
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0026 0.0111
Loa Loa (eye worm) hypothetical protein 0.0033 0.0069 0.018
Echinococcus granulosus phd:f box containing protein 0.0033 0.0069 0.0123
Brugia malayi jmjC domain containing protein 0.0033 0.0069 0.0186
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0632 0.2696
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0632 0.2696
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0192 0.0696 1
Onchocerca volvulus 0.0247 0.0914 0.2533
Loa Loa (eye worm) beta-lactamase 0.0037 0.0087 0.023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Mycobacterium ulcerans NAD synthetase 0.0085 0.0276 0.0817
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0101 0.018
Entamoeba histolytica hypothetical protein 0.0036 0.0083 0.0319
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0079 0.0251 0.0694
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0796 0.2209
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0016
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0298 0.1115 0.3347
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0017 0.0039
Onchocerca volvulus 0.0017 0.0008 0.0003
Schistosoma mansoni organic anion transporter 0.0115 0.0396 0.0699
Loa Loa (eye worm) hypothetical protein 0.0022 0.0025 0.0057
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0022 0.0025 0.0045
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0008 0.001
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0026 0.0046
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0052
Plasmodium falciparum metacaspase-like protein 0.0018 0.0012 0.0024
Brugia malayi sodium-independent organic anion transporter family protein 0.0115 0.0396 0.1097
Schistosoma mansoni nuclear receptor 0.0017 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0083 0.0353
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0995 0.4243
Brugia malayi nuclear hormone receptor 0.0017 0.0007 0.0013
Brugia malayi hypothetical protein 0.0115 0.0396 0.1097
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0425 0.1619 0.486
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0052
Onchocerca volvulus 0.0032 0.0067 0.0167
Schistosoma mansoni inositol monophosphatase 0.0038 0.0091 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0036 0.0083 0.0224
Echinococcus multilocularis phd:f box containing protein 0.0033 0.0069 0.0069
Leishmania major hypothetical protein, conserved 0.0033 0.0069 0.0101
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0087 0.0237
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0446 0.0788
Trichomonas vaginalis abcb9, putative 0.0022 0.0026 0.0111
Echinococcus granulosus jumonji domain containing 1A 0.0033 0.0069 0.0123
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Trichomonas vaginalis abcb9, putative 0.0022 0.0026 0.0111
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0012 0.0012
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0026 0.0183
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0083 0.0218
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0008 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0995 0.4243
Echinococcus multilocularis mitogen activated protein kinase 3 0.0106 0.0359 0.0359
Echinococcus granulosus lysine specific demethylase 6a 0.0033 0.0069 0.0123
Loa Loa (eye worm) hypothetical protein 0.0115 0.0396 0.1092
Schistosoma mansoni organic anion transporter 0.0115 0.0396 0.0699
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0036 0.0082 0.0147
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0037 0.0096
Giardia lamblia Kinase, CMGC MAPK 0.0106 0.0359 0.0405
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0199 0.0348
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0017 0.0007 0.0007
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0018 0.0012 0.0027
Echinococcus granulosus mitogen activated protein kinase 0.0106 0.0359 0.0639
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.2346 1
Echinococcus multilocularis microtubule associated protein 2 0.1439 0.5621 0.5621
Schistosoma mansoni lipoxygenase 0.0106 0.0357 0.0631
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0037 0.0097
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0435 0.1201
Onchocerca volvulus 0.0017 0.0008 0.0003
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0069 0.018
Brugia malayi hypothetical protein 0.0043 0.0108 0.0295
Echinococcus granulosus muscleblind protein 0.0311 0.117 0.2081
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0008 0.0035
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0008 0.0003
Brugia malayi orphan nuclear receptor NR2E1 0.0017 0.0007 0.0013
Mycobacterium ulcerans beta-lactamase 0.0037 0.0087 0.0248
Echinococcus multilocularis cysteine protease 0.0017 0.0008 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0127 0.0127
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0019 0.0015 0.003
Trypanosoma brucei NAD+ synthase, putative 0.0085 0.0276 0.0426
Onchocerca volvulus 0.0037 0.0087 0.0223
Plasmodium vivax JmjC domain containing protein 0.0033 0.0069 0.0882
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0026 0.0046
Toxoplasma gondii ABC1 family protein 0.0037 0.0087 0.0814
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0012 0.0016
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0026 0.0026
Trypanosoma cruzi metacaspase, putative 0.0018 0.0012 0.0012
Schistosoma mansoni glutaminase 0.0283 0.1057 0.1876
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0067 0.0114
Onchocerca volvulus Putative organic anion transporter 0.0115 0.0396 0.1085
Brugia malayi nuclear receptor NHR-88 0.0036 0.0083 0.0224
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0036 0.0083 0.0147
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0087 0.0371
Onchocerca volvulus Putative organic anion transporter 0.0115 0.0396 0.1085
Brugia malayi SPARC precursor 0.0079 0.0251 0.0694
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0026 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0995 0.4243
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0087 0.0237
Trypanosoma cruzi MFS transporter, putative 0.0115 0.0396 0.0615
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0267 0.0995 0.2771
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0091 0.026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Loa Loa (eye worm) hypothetical protein 0.0115 0.0396 0.1092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Schistosoma mansoni nuclear receptor 0.0017 0.0007 0.0007
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0019 0.0015 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0036 0.0083 0.0142
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0026 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0085 0.0276 0.2762
Plasmodium vivax GMP synthetase, putative 0.0034 0.0074 0.0956
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0007 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0052
Trypanosoma cruzi metacaspase, putative 0.0018 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0083 0.0218
Loa Loa (eye worm) hypothetical protein 0.0037 0.0087 0.023
Leishmania major NAD synthase, putative 0.0085 0.0276 0.0426
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0085 0.0276 0.0485
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0359 0.1532
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0106 0.0359 0.0558
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0036 0.0083 0.0147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0036 0.0083 0.0218
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Loa Loa (eye worm) hypothetical protein 0.0033 0.0069 0.018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0067 0.0119
Brugia malayi Nuclear hormone receptor E75 0.0017 0.0007 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0087 0.013
Brugia malayi GMP synthase 0.0034 0.0074 0.02
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0026 0.0111
Onchocerca volvulus 0.0017 0.0008 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0127 0.0226
Schistosoma mansoni polycystin 1-related 0.0041 0.0101 0.0174
Treponema pallidum fructose-bisphosphate aldolase 0.0609 0.2346 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.0219 0.0384
Loa Loa (eye worm) hypothetical protein 0.0115 0.0396 0.1092
Brugia malayi Steroid receptor seven-up type 2 0.0036 0.0083 0.0224
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0037 0.0086
Brugia malayi conserved hypotetical protein 0.0017 0.0007 0.0013
Echinococcus granulosus FTZ F1 alpha 0.0036 0.0083 0.0147
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0127 0.022
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0091 0.0853
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0199 0.0542
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0127 0.0347
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.0359 0.0558
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.003
Echinococcus granulosus transcription factor btf3 0.0036 0.0083 0.0147
Echinococcus multilocularis apoptotic protease activating factor 1 0.0043 0.0108 0.0108
Echinococcus granulosus Solute carrier organic anion transporter family 0.0115 0.0396 0.0704
Plasmodium vivax multidrug resistance protein 1, putative 0.0022 0.0026 0.0258
Brugia malayi Doublecortin family protein 0.0041 0.0101 0.0275
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0019 0.0015 0.0022
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0071 0.0219 0.0933
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0052
Brugia malayi hypothetical protein 0.0115 0.0396 0.1097
Loa Loa (eye worm) glutaminase 2 0.0283 0.1057 0.2939
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0017 0.0007 0.0007
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0033 0.0069 0.0627
Brugia malayi hypothetical protein 0.0026 0.0043 0.0113
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0067 0.0067
Brugia malayi MH2 domain containing protein 0.0125 0.0435 0.1206
Brugia malayi CXXC zinc finger family protein 0.006 0.0176 0.0485
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0006
Onchocerca volvulus 0.0017 0.0008 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0043 0.006
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0008 0.0006
Onchocerca volvulus 0.0037 0.0087 0.0223
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Mycobacterium ulcerans GMP synthase 0.0034 0.0074 0.0209
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0021
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0199 0.0548
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0087 0.0371
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0026 0.0111
Loa Loa (eye worm) hypothetical protein 0.0034 0.0074 0.0194
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0087 0.0371
Brugia malayi beta-NAC-like protein 0.0036 0.0083 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0036 0.0083 0.0224
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0026 0.0111
Leishmania major metacaspase, putative 0.0018 0.0012 0.0012
Schistosoma mansoni cpg binding protein 0.0063 0.019 0.0332
Echinococcus multilocularis caspase 2 0.0061 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0127 0.022
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.003
Trypanosoma cruzi NAD+ synthase, putative 0.0085 0.0276 0.0426
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Loa Loa (eye worm) hypothetical protein 0.0079 0.0251 0.0688
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0101 0.1348
Echinococcus granulosus agrin 0.0079 0.0251 0.0447
Echinococcus multilocularis muscleblind protein 1 0.0311 0.117 0.117
Brugia malayi Inositol-1 0.0038 0.0091 0.0247
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.001
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0034 0.0074 0.0109
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0036 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0036 0.0083 0.0218
Loa Loa (eye worm) hypothetical protein 0.0061 0.0181 0.0491
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0079 0.0251 0.0688
Brugia malayi hypothetical protein 0.0041 0.0101 0.0275
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0069 0.0101
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0026 0.0111
Onchocerca volvulus Bile acid receptor homolog 0.0036 0.0083 0.0211
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Loa Loa (eye worm) hypothetical protein 0.0025 0.0037 0.009
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0091 0.0387
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0359 0.1532
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Brugia malayi hypothetical protein 0.0923 0.3586 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0041 0.0101 0.0269
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0079 0.0251 0.2509
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0106 0.0359 0.0558
Loa Loa (eye worm) hypothetical protein 0.0115 0.0396 0.1092
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0067 0.0114
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.0007 0.0013
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0012 0.004
Trichomonas vaginalis set domain proteins, putative 0.0246 0.0913 0.3892
Trichomonas vaginalis hypothetical protein 0.0192 0.0696 0.2967
Plasmodium falciparum multidrug resistance protein 1 0.0022 0.0026 0.011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0083 0.0147
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0192 0.0696 0.2084
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0036 0.0083 0.0224
Trypanosoma brucei Metacaspase-4 0.0018 0.0012 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0632 0.2696
Brugia malayi hypothetical protein 0.0017 0.0007 0.0013
Brugia malayi sodium-independent organic anion transporter family protein 0.0115 0.0396 0.1097
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0036 0.0083 0.0142
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0425 0.1619 1
Trypanosoma brucei protein kinase, putative 0.0106 0.0359 0.0558
Brugia malayi photoreceptor-specific nuclear receptor 0.0036 0.0083 0.0224
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0017 0.0031
Loa Loa (eye worm) runx1 0.0116 0.0397 0.1096
Schistosoma mansoni smdr2 0.0022 0.0026 0.0041
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0036 0.0083 0.0147
Onchocerca volvulus 0.0115 0.0396 0.1085
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0026 0.0111
Echinococcus multilocularis nuclear receptor nhr 48 0.0017 0.0007 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0037 0.0051
Schistosoma mansoni cpg binding protein 0.006 0.0176 0.0308
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0036 0.0083 0.0147
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0012 0.0012
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0026 0.0076
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0087 0.013
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1627 0.6362 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0037 0.0051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0083 0.0218
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0026 0.0046
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0012 0.004
Leishmania major mitochondrial DNA polymerase beta 0.1627 0.6362 1
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0006
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0079 0.0251 0.0694
Plasmodium vivax SET domain protein, putative 0.0032 0.0067 0.0854
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0079 0.0251 0.2509
Schistosoma mansoni hypothetical protein 0.0175 0.0632 0.112
Echinococcus multilocularis transcription factor btf3 0.0036 0.0083 0.0083
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0008 0.0008
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0392 0.3969
Onchocerca volvulus Putative organic anion transporter 0.0115 0.0396 0.1085
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0033 0.0069 0.0101
Onchocerca volvulus 0.0017 0.0008 0.0003
Brugia malayi RNA binding protein 0.0066 0.0199 0.0548
Brugia malayi jmjC domain containing protein 0.0123 0.0424 0.1176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0006
Echinococcus granulosus RUN 0.0041 0.0101 0.018
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0026 0.0111
Loa Loa (eye worm) hypothetical protein 0.0037 0.0087 0.023
Loa Loa (eye worm) inositol-1 0.0038 0.0091 0.0241
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0087 0.0237
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0199 0.0542
Loa Loa (eye worm) hypothetical protein 0.0037 0.0087 0.023
Brugia malayi Pre-SET motif family protein 0.0217 0.0796 0.2213
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0087 0.0155
Echinococcus granulosus tar DNA binding protein 0.0066 0.0199 0.0354
Echinococcus granulosus survival motor neuron protein 1 0.0245 0.0906 0.1612
Trypanosoma cruzi metacaspase, putative 0.0018 0.0012 0.0012
Brugia malayi beta-lactamase family protein 0.0037 0.0087 0.0236
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0036 0.0083 0.0224
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0091 0.0162
Onchocerca volvulus 0.005 0.0137 0.0363
Onchocerca volvulus Glucosylceramidase homolog 0.0175 0.0632 0.1747
Schistosoma mansoni jumonji/arid domain-containing protein 0.0126 0.0437 0.0773
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0101 0.0101
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0083 0.0462
Schistosoma mansoni multidrug resistance protein 0.0022 0.0026 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0632 0.2696
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0192 0.0696 0.4167
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0199 0.0348
Schistosoma mansoni microtubule-associated protein tau 0.1439 0.5621 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0067 0.0114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0036 0.0083 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0995 0.4243
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0101 0.018
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0067 0.0067
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.0359 0.0558
Brugia malayi hypothetical protein 0.0037 0.0087 0.0236
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0083 0.0224
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0037 0.0096
Onchocerca volvulus 0.0037 0.0087 0.0223
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1627 0.6362 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0007 0.0007
Entamoeba histolytica NAD synthetase, putative 0.0085 0.0276 0.1143
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0036 0.0083 0.0083
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0106 0.0359 0.0558
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0026 0.0026
Echinococcus granulosus caspase 0.0018 0.0012 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0012 0.0056
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0106 0.0359 0.099
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0008 0.0008
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0179 0.0647 0.1152
Entamoeba histolytica hypothetical protein 0.0037 0.0087 0.0336
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0632 0.2696
Loa Loa (eye worm) hypothetical protein 0.0311 0.117 0.3253
Trichomonas vaginalis abcb9, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0026 0.0111
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0085 0.0276 0.0806
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0087 0.0087
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0425 0.1619 1
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0201 0.0308
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0101 0.0101
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0015 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0995 0.4243
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0127 0.0341
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0106 0.0358 0.0358
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0067 0.0114
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0019 0.0015 0.0027
Onchocerca volvulus 0.0115 0.0396 0.1085
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0091 0.0136
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0087 0.0371
Echinococcus granulosus apoptotic protease activating factor 1 0.0043 0.0108 0.0193
Brugia malayi hypothetical protein 0.0017 0.0007 0.0013
Schistosoma mansoni retinoic acid receptor RXR 0.0138 0.0486 0.0859
Brugia malayi jmjC domain containing protein 0.0033 0.0069 0.0186
Echinococcus granulosus JmjC domain containing protein 4 0.0033 0.0069 0.0123
Schistosoma mansoni caspase-3 (C14 family) 0.0018 0.0012 0.0016
Loa Loa (eye worm) agrin synaptic family protein 0.0079 0.0251 0.0688
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0017 0.0007 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0007 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0037 0.0097
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0026 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0359 0.1532
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0008 0.0016
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.077 0.2979 0.4679
Brugia malayi hypothetical protein 0.0041 0.0101 0.0275
Trypanosoma brucei metacaspase 0.0018 0.0012 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0199 0.0348
Leishmania major hypothetical protein, conserved 0.0037 0.0087 0.013
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0043 0.006
Onchocerca volvulus 0.0025 0.0037 0.0083
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0106 0.0359 0.0558
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0008 0.0015
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0083 0.0224
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0425 0.1619 0.649
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0101 0.0101
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0106 0.0359 0.0558
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.067 0.2855
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0192 0.0696 0.3961
Mycobacterium tuberculosis Conserved protein 0.0037 0.0087 0.0237
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0101 0.018
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0026 0.0111
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0036 0.0083 0.0083
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0007 0.0007
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0033 0.0069 0.0627
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0037 0.0097
Schistosoma mansoni inositol monophosphatase 0.0038 0.0091 0.0156
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.2346 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0037 0.0097
Echinococcus granulosus Nuclear hormone receptor HR96 0.0017 0.0007 0.0013
Brugia malayi jmjC domain containing protein 0.0033 0.0069 0.0186
Entamoeba histolytica hypothetical protein 0.0037 0.0087 0.0336
Brugia malayi nuclear receptor NHR-67 0.0017 0.0007 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0229 0.0843 0.1319
Trichomonas vaginalis esterase, putative 0.0037 0.0087 0.0371
Entamoeba histolytica P-glycoprotein-5 0.0022 0.0026 0.0076
Loa Loa (eye worm) hypothetical protein 0.0025 0.0037 0.009
Schistosoma mansoni GMP synthetase 0.0034 0.0074 0.0126
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0021
Brugia malayi nuclear receptor RXR 0.0019 0.0015 0.0036
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0036 0.0083 0.0218
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0087 0.0248
Brugia malayi prostaglandin transporter 0.0115 0.0396 0.1097
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Onchocerca volvulus 0.0022 0.0026 0.0053
Brugia malayi Cytochrome P450 family protein 0.0027 0.0047 0.0124
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.2346 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0037 0.0097
Onchocerca volvulus 0.0923 0.3586 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0087 0.0237
Loa Loa (eye worm) hypothetical protein 0.0036 0.0083 0.0218
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0008 0.001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0037 0.0097
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0026 0.006
Leishmania major hypothetical protein, conserved 0.0026 0.0043 0.006
Schistosoma mansoni coup transcription factor 0.0036 0.0083 0.0142
Brugia malayi nuclear hormone receptor family member nhr-6 0.0017 0.0007 0.0013
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0091 0.0136
Onchocerca volvulus 0.0115 0.0396 0.1085
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0017 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0087 0.023
Brugia malayi TAR-binding protein 0.0066 0.0199 0.0548
Brugia malayi ABC transporter family protein 0.0022 0.0026 0.0066
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0179 0.0647 0.0647
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0008 0.0009
Echinococcus multilocularis JmjC domain containing protein 4 0.0033 0.0069 0.0069
Schistosoma mansoni lozenge 0.0116 0.0397 0.0702
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Trichomonas vaginalis taga, putative 0.0022 0.0026 0.0111
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0091 0.0353
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0026 0.0111
Loa Loa (eye worm) cysteine protease 0.0017 0.0008 0.001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1627 0.6362 1
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0632 0.2696
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0021
Schistosoma mansoni jumonji/arid domain-containing protein 0.0126 0.0437 0.0773
Echinococcus multilocularis pol protein 0.2548 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0107
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0425 0.1619 0.4866
Trypanosoma brucei metacaspase MCA3 0.0018 0.0012 0.0012
Brugia malayi Cell death protein 3 precursor 0.0061 0.0181 0.0497
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0036 0.0083 0.0218
Entamoeba histolytica P-glycoprotein-1 0.0022 0.0026 0.0076
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0026 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0036 0.0083 0.0147
Brugia malayi Cytochrome P450 family protein 0.0016 0.0005 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0017 0.0017
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0119 0.041 0.041
Onchocerca volvulus 0.0017 0.0008 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0083 0.0083
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0034 0.0074 0.0074
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0106 0.0358 0.0638
Schistosoma mansoni multidrug resistance protein 0.0022 0.0026 0.0041
Loa Loa (eye worm) DR-78 0.0017 0.0007 0.0007
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0241 0.0428
Loa Loa (eye worm) hypothetical protein 0.0115 0.0396 0.1092
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0036 0.0083 0.0142
Trypanosoma brucei metacaspase 5, putative 0.0018 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Schistosoma mansoni jumonji domain containing protein 0.0033 0.0069 0.0117
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0358 0.0633
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0145 0.0221
Schistosoma mansoni thyroid hormone receptor 0.0036 0.0083 0.0142
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0016
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0083 0.0123
Brugia malayi secreted modular calcium-binding protein 1 0.0079 0.0251 0.0694
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0022 0.0026 0.0183
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0298 0.1115 0.334
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0026 0.0111
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0923 0.3586 1
Echinococcus granulosus nuclear receptor nhr 48 0.0017 0.0007 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0036 0.0083 0.0224
Schistosoma mansoni nuclear receptor nhr-48 0.0017 0.0007 0.0007
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0036 0.0083 0.0211
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0176 0.0479
Leishmania major cathepsin L-like protease 0.0066 0.0201 0.0308
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0201 0.0308
Loa Loa (eye worm) hypothetical protein 0.0043 0.0108 0.0289
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0087 0.0237
Schistosoma mansoni phosphatidylserine receptor 0.0033 0.0069 0.0117
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0026 0.0026
Toxoplasma gondii protease inhibitor PI2 0.0079 0.0251 0.2509
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0425 0.1619 1
Echinococcus multilocularis mitogen activated protein kinase 0.0106 0.0359 0.0359
Loa Loa (eye worm) hypothetical protein 0.0115 0.0396 0.1092
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0069 0.018
Plasmodium falciparum metacaspase 1 0.0018 0.0012 0.0024
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0087 0.0318
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.0007 0.0007
Loa Loa (eye worm) ctsf protein 0.0017 0.0008 0.001
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0079 0.0251 0.0694
Brugia malayi jmjC domain containing protein 0.0033 0.0069 0.0186
Echinococcus multilocularis FTZ F1 alpha 0.0036 0.0083 0.0083
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0083 0.077
Echinococcus granulosus caspase 8 0.0018 0.0012 0.0022
Echinococcus multilocularis Protein lozenge 0.0116 0.0397 0.0397
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0358 0.0633
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0075 0.0242
Echinococcus multilocularis pol protein 0.2548 1 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0137 0.0375
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0017 0.0007 0.0007
Echinococcus multilocularis cpg binding protein 0.0063 0.019 0.019
Onchocerca volvulus Cell death protein 3 homolog 0.0061 0.0181 0.0484
Loa Loa (eye worm) hypothetical protein 0.0311 0.117 0.3253
Loa Loa (eye worm) hypothetical protein 0.0036 0.0083 0.0218
Schistosoma mansoni hypothetical protein 0.0853 0.3307 0.5881
Echinococcus granulosus cathepsin l1 0.0017 0.0008 0.0015
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0138 0.0486 0.0864
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Echinococcus granulosus microtubule associated protein 2 0.1439 0.5621 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.0396 0.1092
Schistosoma mansoni transcription factor btf3 0.0036 0.0083 0.0142
Loa Loa (eye worm) hypothetical protein 0.0036 0.0083 0.0218
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0036 0.0083 0.0218
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0037 0.0122
Trichomonas vaginalis glutaminase, putative 0.0283 0.1057 0.4506
Echinococcus multilocularis jumonji domain containing 1A 0.0033 0.0069 0.0069
Mycobacterium ulcerans lipase LipD 0.0037 0.0087 0.0248
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0085 0.0276 0.1659
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0026 0.006
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0069 0.0101
Loa Loa (eye worm) steroid hormone receptor 0.0036 0.0083 0.0218
Trypanosoma cruzi NAD+ synthase, putative 0.0085 0.0276 0.0426
Brugia malayi MAP kinase sur-1 0.0106 0.0359 0.0996
Toxoplasma gondii melibiase subfamily protein 0.0106 0.0358 0.362
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0123 0.0424 0.0754
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0087 0.0149
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.0178 0.0273
Echinococcus granulosus ecdysone induced protein 78C 0.0036 0.0083 0.0147
Schistosoma mansoni survival motor neuron protein 0.005 0.0137 0.0238
Loa Loa (eye worm) hypothetical protein 0.0036 0.0083 0.0218
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0106 0.0358 0.0358
Echinococcus multilocularis thyroid hormone receptor alpha 0.0036 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0043 0.0108 0.0187
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0036 0.0082 0.0082
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0026 0.0111
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0425 0.1619 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0174
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0021
Echinococcus granulosus cpg binding protein 0.0063 0.019 0.0338
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0008 0.0006
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0199 0.0348
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0036 0.0083 0.0224
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0043 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0003 0.0003
Brugia malayi hypothetical protein 0.0019 0.0015 0.0036
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0036 0.0083 0.0142
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Echinococcus granulosus follistatin 0.0079 0.0251 0.0447
Entamoeba histolytica hypothetical protein 0.0037 0.0087 0.0336
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0012 0.0025
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0034 0.0074 0.0408
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0026 0.0046
Brugia malayi nuclear receptor NHR-88 0.0017 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0021
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0043 0.0215
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.0052
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0034 0.0074 0.0132
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0033 0.0069 0.0117
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0026 0.0111
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0087 0.0371
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0087 0.023
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0047 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0083 0.0353
Echinococcus multilocularis lysine specific demethylase 5A 0.0123 0.0424 0.0424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0075 0.0201
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0008 0.0035
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0015 0.0036
Brugia malayi beta-lactamase 0.0037 0.0087 0.0236
Mycobacterium tuberculosis Conserved protein 0.0037 0.0087 0.0237
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0012 0.0058
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0025 0.0025
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0298 0.1115 0.6815
Brugia malayi beta-lactamase family protein 0.0037 0.0087 0.0236
Echinococcus granulosus thyroid hormone receptor alpha 0.0017 0.0007 0.0013
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0251 0.0688
Brugia malayi hypothetical protein 0.0019 0.0015 0.0036
Toxoplasma gondii hypothetical protein 0.0262 0.0976 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0091 0.0136
Loa Loa (eye worm) hypothetical protein 0.0025 0.0037 0.009
Leishmania major cathepsin L-like protease 0.0066 0.0201 0.0308
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0192 0.0696 0.4256
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0026 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.2346 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Toxoplasma gondii transporter, major facilitator family protein 0.0115 0.0396 0.4004
Echinococcus granulosus mitogen activated protein kinase 3 0.0106 0.0359 0.0639
Onchocerca volvulus Protein ultraspiracle homolog 0.0036 0.0083 0.0211
Schistosoma mansoni multidrug resistance protein 0.0022 0.0026 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0083 0.0224
Onchocerca volvulus 0.0036 0.0083 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0079 0.0251 0.2509
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0241 0.0241
Entamoeba histolytica hypothetical protein 0.0037 0.0087 0.0336
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0036 0.0083 0.0218
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0036 0.0083 0.0142
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0435 0.1201
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0012 0.004
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0229 0.0843 0.1319
Brugia malayi hypothetical protein 0.0245 0.0906 0.2522
Brugia malayi multidrug resistance protein 3 0.0022 0.0026 0.0066
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0026 0.0111
Echinococcus multilocularis pol protein 0.2548 1 1
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0016
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0069 0.018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.2346 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0079 0.0251 0.0694
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0026 0.0111
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0051 0.0141 0.0246
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0026 0.0111
Brugia malayi ecdysteroid receptor 0.0036 0.0083 0.0224
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0359 0.1532
Echinococcus granulosus dnaJ subfamily B 0.0853 0.3307 0.5884
Brugia malayi nuclear hormone receptor family member odr-7 0.0017 0.0007 0.0013
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0026 0.0111
Brugia malayi steroid hormone receptor 0.0036 0.0083 0.0224
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0087 0.0155
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0091 0.0091
Schistosoma mansoni RAR-like nuclear receptor 0.0036 0.0083 0.0142
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0043 0.0357
Onchocerca volvulus 0.0115 0.0396 0.1085
Mycobacterium tuberculosis Conserved hypothetical protein 0.0857 0.3323 1
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.0012 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0036 0.0083 0.0224
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0085 0.0276 0.1509
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0003 0.0005
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0043 0.0503
Leishmania major cathepsin L-like protease 0.0066 0.0201 0.0308
Entamoeba histolytica P-glycoprotein-2, putative 0.0022 0.0026 0.0076
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0115 0.0396 0.1092
Schistosoma mansoni protein phosphatase 2C 0.0033 0.0069 0.0117
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0087 0.1144
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0043 0.0215
Leishmania major cathepsin L-like protease 0.0017 0.0008 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0267 0.0995 0.4243
Schistosoma mansoni hypothetical protein 0.005 0.0137 0.0238
Brugia malayi nuclear receptor RXR 0.0017 0.0007 0.0013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0083 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0036 0.0083 0.0224
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0012 0.0052
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0083 0.0123
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0115 0.0396 0.0396
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0036 0.0083 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0609 0.2346 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0609 0.2346 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0036 0.0083 0.0083
Echinococcus multilocularis agrin 0.0079 0.0251 0.0251
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0026 0.0046
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0008 0.0003
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0036 0.0083 0.0142
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0018 0.0012 0.0012
Echinococcus multilocularis follistatin 0.0079 0.0251 0.0251
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0199 0.0348
Mycobacterium ulcerans glutaminase 0.0283 0.1057 0.3172
Loa Loa (eye worm) hypothetical protein 0.0079 0.0251 0.0688
Schistosoma mansoni phd/f-box containing protein 0.0033 0.0069 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0359 0.0634
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.003
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0026 0.0026
Schistosoma mansoni rab6-interacting 0.0041 0.0101 0.0174
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0085 0.0276 0.3885
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0106 0.0359 0.3629
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0087 0.013
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0101 0.0576
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0201 0.0308
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0012 0.0012
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0057 0.0102
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0037 0.0051
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0085 0.0276 0.1174
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0609 0.2346 1
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0192 0.0696 0.711
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Brugia malayi Cytochrome P450 family protein 0.0016 0.0005 0.0006
Loa Loa (eye worm) nuclear hormone receptor 0.0017 0.0007 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0127 0.022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.003
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0087 0.0248
Schistosoma mansoni hypothetical protein 0.0175 0.0632 0.112
Loa Loa (eye worm) glutaminase 0.0283 0.1057 0.2939
Brugia malayi sodium-independent organic anion transporter family protein 0.0115 0.0396 0.1097
Loa Loa (eye worm) nuclear receptor NHR-67 0.0017 0.0007 0.0007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0036 0.0083 0.0083
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0127 0.0127
Brugia malayi hypothetical protein 0.0017 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Echinococcus multilocularis geminin 0.0175 0.0632 0.0632
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0079 0.0251 0.2509
Brugia malayi Muscleblind-like protein 0.0311 0.117 0.3257
Mycobacterium ulcerans hypothetical protein 0.0857 0.3323 1
Echinococcus multilocularis RUN 0.0041 0.0101 0.0101
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.077 0.2979 0.4679
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0201 0.0308
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0091 0.0387
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0267 0.0995 0.2766
Schistosoma mansoni hypothetical protein 0.0041 0.0101 0.0174
Onchocerca volvulus 0.006 0.0176 0.0472
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0083 0.0353
Echinococcus multilocularis caspase 0.0018 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.01 0.0336 0.0593
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0037 0.0097
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0091 0.0387
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0087 0.0237
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.088 0.263
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0034 0.0074 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0008 0.0035
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0087 0.0236
Echinococcus multilocularis dnaJ subfamily B 0.0853 0.3307 0.3307
Echinococcus multilocularis lysine specific demethylase 6a 0.0033 0.0069 0.0069
Loa Loa (eye worm) histone methyltransferase 0.002 0.0017 0.0036
Onchocerca volvulus 0.0041 0.0101 0.0262
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0036 0.0083 0.0224
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0083 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0026 0.0026
Loa Loa (eye worm) RNA binding protein 0.0066 0.0199 0.0542
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0358 0.0633
Echinococcus granulosus lysine specific demethylase 5A 0.0126 0.0437 0.0778
Brugia malayi glutaminase DH11.1 0.0283 0.1057 0.2943
Entamoeba histolytica P-glycoprotein-2 0.0022 0.0026 0.0076
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0101 0.0269
Onchocerca volvulus 0.0043 0.0108 0.0282
Brugia malayi nuclear hormone receptor 0.0036 0.0083 0.0224
Plasmodium falciparum enoyl-acyl carrier reductase 0.0192 0.0696 0.427
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0115 0.0396 0.0704
Mycobacterium ulcerans hypothetical protein 0.0037 0.0087 0.0248
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0069 0.018
Echinococcus multilocularis cysteine protease 0.0017 0.0008 0.0008
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0012 0.0023
Brugia malayi Melibiase family protein 0.0071 0.0219 0.0604
Schistosoma mansoni thyroid hormone receptor 0.0036 0.0083 0.0142
Schistosoma mansoni lipoxygenase 0.0179 0.0647 0.1147
Schistosoma mansoni cpg binding protein 0.0063 0.019 0.0332
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0229 0.0843 0.1319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0008 0.0035
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0087 0.0149
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0018 0.0012 0.0022
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0083 0.0123
Schistosoma mansoni caspase-7 (C14 family) 0.0061 0.0181 0.0316
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0016
Brugia malayi Pre-SET motif family protein 0.0032 0.0067 0.018
Loa Loa (eye worm) hypothetical protein 0.0079 0.0251 0.0688
Plasmodium vivax metacaspase 1, putative 0.0018 0.0012 0.0056
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.0083 0.0319
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0037 0.0122
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0083 0.1082
Loa Loa (eye worm) hypothetical protein 0.0037 0.0087 0.023
Loa Loa (eye worm) hypothetical protein 0.0071 0.0219 0.0599
Onchocerca volvulus 0.0041 0.0101 0.0262
Plasmodium falciparum JmjC domain-containing protein, putative 0.0033 0.0069 0.0377
Onchocerca volvulus 0.0079 0.0251 0.0681
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0358 0.0633
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Echinococcus multilocularis survival motor neuron protein 1 0.0245 0.0906 0.0906
Trypanosoma brucei metacaspase MCA2 0.0018 0.0012 0.0012
Brugia malayi tailless protein 0.0017 0.0007 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0036 0.0083 0.0224
Brugia malayi Cathepsin L-like precursor 0.0017 0.0008 0.0016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.0219 0.0384
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0015 0.0022
Trypanosoma cruzi metacaspase, putative 0.0018 0.0012 0.0012
Leishmania major p-glycoprotein 0.0022 0.0026 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.067 0.2855
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0609 0.2346 1
Echinococcus granulosus caspase 2 0.0061 0.0181 0.0321
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0201 0.0308
Brugia malayi ecdysone receptor 0.0017 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0087 0.023
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0192 0.0696 0.2075
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0008 0.0008

Activities

Activity type Activity value Assay description Source Reference
Blood sugar lowering (functional) = 10 % Ability to lower blood sugar level at the dose of 10 mg/kg in fasted rats, by using glucose tolerance test(GTT) ChEMBL. 3701788

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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