Detailed information for compound 290856

Basic information

Technical information
  • TDR Targets ID: 290856
  • Name: (1-methylindol-5-yl) 3,4,5-trimethoxybenzenes ulfonate
  • MW: 377.412 | Formula: C18H19NO6S
  • H donors: 0 H acceptors: 2 LogP: 3.01 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(cc(c1OC)OC)S(=O)(=O)Oc1ccc2c(c1)ccn2C
  • InChi: 1S/C18H19NO6S/c1-19-8-7-12-9-13(5-6-15(12)19)25-26(20,21)14-10-16(22-2)18(24-4)17(11-14)23-3/h5-11H,1-4H3
  • InChiKey: LVPPMYDKCSYLSR-UHFFFAOYSA-N  


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Synonyms

  • 3,4,5-trimethoxybenzenesulfonic acid (1-methyl-5-indolyl) ester
  • 3,4,5-trimethoxybenzenesulfonic acid (1-methylindol-5-yl) ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Sus scrofa Tubulin alpha chain Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha-3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii alpha-tubulin I, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha-2/alpha-4 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Entamoeba histolytica tubulin alpha-1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii Tubulin/FtsZ family, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha-1C chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium berghei alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Theileria parva tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Babesia bovis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium parvum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Candida albicans cytoskeletal structural protein Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi tubulin alpha chain - mouse Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Babesia bovis tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum alpha tubulin 2 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Giardia lamblia Alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium knowlesi alpha-tubulin II, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania donovani alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Entamoeba histolytica tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Cryptosporidium hominis alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum Tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha-2 chain Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) tubulin alpha 2 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania braziliensis alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus tubulin alpha 3 chain Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium yoelii tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium vivax tubulin alpha chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Neospora caninum tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) alpha-tubulin isotype 2 Get druggable targets OG5_126605 All targets in OG5_126605
Toxoplasma gondii alpha tubulin TUBA1 Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Brugia malayi Tubulin alpha chain Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania infantum alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma japonicum ko:K07374 tubulin alpha, putative Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) alpha-tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis Tubulin alpha 1 chain Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin beta chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin epsilon chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126605 All targets in OG5_126605
Plasmodium falciparum alpha tubulin 1 Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin subunit TubB Get druggable targets OG5_126605 All targets in OG5_126605
Trichomonas vaginalis tubulin alpha-1 chain, putative Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania major alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus granulosus peroxisome assembly protein 26 Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma brucei gambiense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Echinococcus multilocularis tubulin alpha 1C chain Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma cruzi alpha tubulin, putative Get druggable targets OG5_126605 All targets in OG5_126605
Trypanosoma congolense alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Leishmania mexicana alpha tubulin Get druggable targets OG5_126605 All targets in OG5_126605
Schistosoma mansoni tubulin subunit alpha Get druggable targets OG5_126605 All targets in OG5_126605
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni tubulin subunit epsilon Tubulin alpha chain   451 aa 469 aa 27.9 %
Entamoeba histolytica tubulin family protein Tubulin alpha chain   451 aa 434 aa 39.4 %
Schistosoma mansoni tubulin subunit beta Tubulin alpha chain   451 aa 434 aa 40.1 %
Entamoeba histolytica tubulin family protein Tubulin alpha chain   451 aa 434 aa 40.1 %
Cryptosporidium hominis gamma-tubulin Tubulin alpha chain   451 aa 443 aa 30.9 %
Schistosoma mansoni tubulin subunit gamma Tubulin alpha chain   451 aa 451 aa 31.5 %
Loa Loa (eye worm) tubulin beta-1 chain Tubulin alpha chain   451 aa 437 aa 39.4 %
Drosophila melanogaster beta-Tubulin at 60D Tubulin alpha chain   451 aa 439 aa 39.2 %
Onchocerca volvulus Tubulin alpha chain   451 aa 434 aa 41.5 %
Echinococcus granulosus tubulin gamma 1 chain Tubulin alpha chain   451 aa 455 aa 31.4 %
Echinococcus granulosus Tubulin beta 2C chain Tubulin alpha chain   451 aa 434 aa 40.3 %
Giardia lamblia Gamma tubulin Tubulin alpha chain   451 aa 467 aa 29.6 %
Plasmodium yoelii tubulin beta chain Tubulin alpha chain   451 aa 455 aa 26.8 %
Onchocerca volvulus Tubulin alpha chain   451 aa 441 aa 74.4 %
Babesia bovis tubulin, putative Tubulin alpha chain   451 aa 463 aa 20.7 %
Theileria parva tubulin gamma chain, putative Tubulin alpha chain   451 aa 462 aa 29.7 %
Leishmania braziliensis epsilon tubulin, putative Tubulin alpha chain   451 aa 469 aa 29.4 %
Dictyostelium discoideum beta tubulin Tubulin alpha chain   451 aa 443 aa 40.4 %
Trypanosoma brucei gambiense epsilon tubulin Tubulin alpha chain   451 aa 479 aa 25.7 %
Plasmodium yoelii tubulin gamma chain Tubulin alpha chain   451 aa 431 aa 31.3 %
Plasmodium falciparum tubulin gamma chain Tubulin alpha chain   451 aa 431 aa 31.8 %
Giardia lamblia Epsilon tubulin Tubulin alpha chain   451 aa 457 aa 29.3 %
Plasmodium falciparum tubulin epsilon chain, putative Tubulin alpha chain   451 aa 465 aa 25.8 %
Echinococcus granulosus tubulin alpha Tubulin alpha chain   451 aa 433 aa 40.0 %
Leishmania major epsilon tubulin, putative Tubulin alpha chain   451 aa 469 aa 27.5 %
Neospora caninum Beta-tubulin, related Tubulin alpha chain   451 aa 417 aa 31.4 %
Leishmania mexicana epsilon tubulin, putative Tubulin alpha chain   451 aa 469 aa 27.7 %
Plasmodium vivax tubulin epsilon chain, putative Tubulin alpha chain   451 aa 458 aa 26.2 %
Schistosoma japonicum ko:K10389 tubulin gamma, putative Tubulin alpha chain   451 aa 434 aa 31.8 %
Plasmodium berghei tubulin epsilon chain, putative Tubulin alpha chain   451 aa 455 aa 27.7 %
Onchocerca volvulus Regulatory-associated protein of mTOR homolog Tubulin alpha chain   451 aa 439 aa 76.3 %
Plasmodium knowlesi tubulin epsilon chain, putative Tubulin alpha chain   451 aa 454 aa 26.2 %
Trypanosoma brucei epsilon tubulin Tubulin alpha chain   451 aa 479 aa 25.5 %
Echinococcus multilocularis tubulin, beta 4A class IVa Tubulin alpha chain   451 aa 388 aa 38.9 %
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein Tubulin alpha chain   451 aa 436 aa 38.8 %
Trypanosoma cruzi epsilon tubulin, putative Tubulin alpha chain   451 aa 474 aa 27.4 %
Trypanosoma cruzi epsilon tubulin, putative Tubulin alpha chain   451 aa 474 aa 27.4 %
Onchocerca volvulus Putative cytochrome c-type heme lyase Tubulin alpha chain   451 aa 434 aa 39.2 %
Neospora caninum tubulin alpha chain, putative Tubulin alpha chain   451 aa 436 aa 37.4 %
Leishmania mexicana beta tubulin Tubulin alpha chain   451 aa 434 aa 42.4 %
Echinococcus multilocularis tubulin alpha Tubulin alpha chain   451 aa 436 aa 40.1 %
Echinococcus multilocularis Tubulin beta 2C chain Tubulin alpha chain   451 aa 434 aa 41.5 %
Cryptosporidium parvum gamma tubulin Tubulin alpha chain   451 aa 443 aa 30.9 %
Plasmodium vivax tubulin gamma chain, putative Tubulin alpha chain   451 aa 429 aa 30.8 %
Onchocerca volvulus Putative methyltransferase KIAA1456 Tubulin alpha chain   451 aa 441 aa 31.7 %
Babesia bovis tubulin gamma chain Tubulin alpha chain   451 aa 429 aa 31.7 %
Dictyostelium discoideum gamma tubulin Tubulin alpha chain   451 aa 436 aa 32.8 %
Echinococcus granulosus tubulin beta 4A class IVa Tubulin alpha chain   451 aa 388 aa 38.9 %
Echinococcus multilocularis tubulin gamma 1 chain Tubulin alpha chain   451 aa 455 aa 31.4 %
Schistosoma mansoni tubulin subunit beta Tubulin alpha chain   451 aa 435 aa 40.9 %
Brugia malayi Tubulin beta-1 chain Tubulin alpha chain   451 aa 434 aa 39.6 %
Loa Loa (eye worm) BEN-1 protein Tubulin alpha chain   451 aa 434 aa 41.5 %
Trypanosoma brucei epsilon tubulin Tubulin alpha chain   451 aa 478 aa 25.7 %
Leishmania infantum epsilon tubulin, putative Tubulin alpha chain   451 aa 471 aa 27.0 %
Trypanosoma brucei epsilon tubulin Tubulin alpha chain   451 aa 478 aa 25.7 %
Onchocerca volvulus Tubulin alpha chain   451 aa 438 aa 84.7 %
Echinococcus granulosus Tubulin beta 2C chain Tubulin alpha chain   451 aa 434 aa 41.5 %
Echinococcus multilocularis tubulin delta chain Tubulin alpha chain   451 aa 401 aa 22.9 %
Onchocerca volvulus Tyrosine kinase homolog Tubulin alpha chain   451 aa 439 aa 87.7 %
Trichomonas vaginalis tubulin gamma chain, putative Tubulin alpha chain   451 aa 422 aa 28.4 %
Echinococcus multilocularis Tubulin beta 2C chain Tubulin alpha chain   451 aa 434 aa 40.6 %
Plasmodium berghei tubulin gamma chain, putative Tubulin alpha chain   451 aa 431 aa 31.1 %
Trypanosoma congolense epsilon tubulin Tubulin alpha chain   451 aa 472 aa 26.5 %
Entamoeba histolytica tubulin gamma chain Tubulin alpha chain   451 aa 434 aa 30.9 %
Plasmodium knowlesi tubulin gamma chain, putative Tubulin alpha chain   451 aa 429 aa 30.8 %
Leishmania donovani epsilon tubulin, putative Tubulin alpha chain   451 aa 471 aa 27.0 %
Drosophila melanogaster gamma-Tubulin at 23C Tubulin alpha chain   451 aa 446 aa 32.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.006 0.0191 0.0248
Onchocerca volvulus 0.0141 0.0745 0.1323
Loa Loa (eye worm) TK protein kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis tyrosine protein kinase csk 0.0032 0.0003 0.0003
Giardia lamblia Kinase, CMGC MAPK 0.0041 0.0061 0.025
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0012
Brugia malayi serine/threonine-protein kinase 6 0.0299 0.1833 0.2505
Loa Loa (eye worm) TK protein kinase 0.0052 0.0139 0.0165
Schistosoma mansoni tyrosine kinase 0.0711 0.4653 0.6054
Echinococcus granulosus retinal guanylyl cyclase 2 0.0032 0.0003 0.0003
Loa Loa (eye worm) serine/threonine protein kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0053 0.0143 0.0185
Echinococcus granulosus raf serine:threonine protein kinase 0.0032 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0299 0.1833 0.7756
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0032 0.0003 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.0054 0.0064
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0032 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0017 0.0023
Schistosoma mansoni kinase 0.0544 0.3508 0.4564
Trichomonas vaginalis CAMK family protein kinase 0.0377 0.2362 1
Entamoeba histolytica cyclin family protein 0.0046 0.0094 0.0387
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0049 0.0117 0.0153
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0183 0.1035 0.564
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0041 0.0061 0.0322
Schistosoma mansoni protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK/INSR protein kinase 0.0944 0.6252 0.7394
Loa Loa (eye worm) TK/DDR protein kinase 0.0032 0.0003 0.0003
Toxoplasma gondii CMGC kinase, CK2 family 0.0183 0.1035 0.564
Schistosoma mansoni cell adhesion molecule 0.0045 0.0091 0.0118
Entamoeba histolytica protein kinase, putative 0.0044 0.0084 0.0345
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0609 0.2569
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0038 0.0039 0.0051
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0032 0.0003 0.0003
Trichomonas vaginalis cyclins, putative 0.0046 0.0094 0.0387
Echinococcus multilocularis protein kinase c epsilon type 0.0038 0.0039 0.0051
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0064 0.0216 0.1169
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0032 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0299 0.1833 0.7756
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0032 0.0003 0.0003
Echinococcus multilocularis cyclins 0.0046 0.0094 0.0122
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0091 0.0124
Trichomonas vaginalis cyclin B, putative 0.0046 0.0094 0.0387
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0438 0.1844
Schistosoma mansoni septate junction protein 0.0045 0.0091 0.0118
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0061 0.025
Giardia lamblia Kinase, AGC PKA 0.0064 0.0216 0.0906
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0038 0.0039 0.0051
Echinococcus granulosus tyrosine protein kinase csk 0.0032 0.0003 0.0003
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0038 0.0039 0.0051
Onchocerca volvulus 0.0046 0.0094 0.0167
Schistosoma mansoni aldehyde dehydrogenase 0.0036 0.003 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0061 0.025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Plasmodium falciparum cysteine repeat modular protein 2 0.0034 0.001 0.004
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0035 0.0022 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0041 0.0058 0.0237
Schistosoma mansoni cyclin B3 0.0046 0.0094 0.0122
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0091 0.0124
Loa Loa (eye worm) TK/ALK protein kinase 0.0032 0.0003 0.0003
Brugia malayi Raf kinase 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0032 0.0003 0.0005
Echinococcus multilocularis receptor type guanylyl cyclase 0.0032 0.0003 0.0003
Trypanosoma brucei protein kinase, putative 0.0043 0.0076 0.0313
Echinococcus granulosus tyrosine protein kinase Src64B 0.0127 0.065 0.0845
Schistosoma mansoni protein kinase 0.0043 0.0076 0.0099
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0127 0.065 0.0845
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0438 0.1844
Brugia malayi Cyclin, N-terminal domain containing protein 0.0046 0.0094 0.0128
Onchocerca volvulus 0.0034 0.0017 0.0029
Trypanosoma cruzi CYC2-like cyclin, putative 0.0046 0.0094 0.0387
Mycobacterium tuberculosis Conserved hypothetical protein 0.0049 0.0117 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.009 0.0118
Plasmodium vivax hypothetical protein, conserved 0.0034 0.001 0.004
Schistosoma mansoni protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0042 0.0069 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0675 0.2851
Echinococcus granulosus hemicentin 1 0.0045 0.0091 0.0118
Brugia malayi Prion-like- 0.0045 0.0091 0.0124
Loa Loa (eye worm) AUR protein kinase 0.0299 0.1833 0.2168
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.004 0.0051 0.0207
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0299 0.1833 1
Toxoplasma gondii aurora kinase 0.0299 0.1833 1
Trypanosoma brucei rac serine-threonine kinase, putative 0.0096 0.0438 0.1844
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Entamoeba histolytica cysteine-rich surface protein, putative 0.0034 0.001 0.0031
Brugia malayi serine/threonine kinase 12 0.0299 0.1833 0.2505
Trichomonas vaginalis cyclins, putative 0.0046 0.0094 0.0387
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Loa Loa (eye worm) cyclin domain-containing protein 0.0046 0.0094 0.0111
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0038 0.0039 0.0046
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0032 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0017 0.0023
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0032 0.0003 0.0003
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0117 0.0585 0.0761
Schistosoma mansoni vesicular amine transporter 0.0088 0.0383 0.0499
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0042 0.0069 0.0123
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0032 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0042 0.0069 0.0094
Echinococcus multilocularis protein tyrosine kinase 0.0681 0.4452 0.5793
Echinococcus granulosus defective proboscis extension response 0.0088 0.0383 0.0499
Brugia malayi Protein kinase domain containing protein 0.0042 0.0069 0.0094
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0108
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Loa Loa (eye worm) hypothetical protein 0.011 0.0535 0.0633
Echinococcus granulosus tyrosine protein kinase otk 0.0045 0.0091 0.0118
Trypanosoma brucei polo-like protein kinase 0.0377 0.2362 1
Echinococcus multilocularis aurora kinase A 0.0299 0.1833 0.2384
Brugia malayi bone morphogenetic protein type 1 receptor 0.0032 0.0003 0.0003
Echinococcus granulosus nephrin 0.0034 0.0017 0.0021
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0052 0.0139 0.0181
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.006 0.0191 0.0226
Loa Loa (eye worm) TK protein kinase 0.0117 0.0585 0.0692
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0113 0.0558 0.0726
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0032 0.0003 0.0003
Schistosoma mansoni cell adhesion molecule 0.006 0.0191 0.0248
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.1035 0.4375
Leishmania major protein kinase, putative 0.0299 0.1833 0.7756
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0127 0.065 0.0845
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0052 0.0139 0.019
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.003 0.003
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0041 0.0061 0.025
Onchocerca volvulus 0.0032 0.0003 0.0005
Loa Loa (eye worm) TK/CSK protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK/Met protein kinase 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0042 0.0069 0.0123
Echinococcus multilocularis tyrosine protein kinase shark 0.0042 0.0069 0.009
Echinococcus multilocularis cyclins 0.0046 0.0094 0.0122
Brugia malayi integrin-linked kinase 0.0032 0.0003 0.0003
Leishmania major cyclin 0.0046 0.0094 0.0387
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0022 0.0028
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0017 0.0023
Echinococcus granulosus protein kinase c iota type 0.0038 0.0039 0.0051
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0121 0.0609 0.072
Trypanosoma cruzi polo-like protein kinase, putative 0.0377 0.2362 1
Echinococcus multilocularis neuroglian 0.0108 0.052 0.0676
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0127 0.065 0.0845
Brugia malayi cell division control protein 2 homolog 0.0121 0.0609 0.0832
Echinococcus multilocularis tyrosine protein kinase otk 0.0045 0.0091 0.0118
Loa Loa (eye worm) hypothetical protein 0.0103 0.0483 0.0572
Brugia malayi Protein kinase domain containing protein 0.0042 0.0069 0.0094
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Loa Loa (eye worm) TK/FAK protein kinase 0.0689 0.4505 0.5329
Onchocerca volvulus 0.0034 0.001 0.0018
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0049 0.0117 0.0139
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0127 0.065 0.0845
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0042 0.0069 0.009
Echinococcus granulosus tyrosine protein kinase shark 0.0042 0.0069 0.009
Echinococcus multilocularis tyrosine protein kinase csk 0.0032 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0438 0.1844
Echinococcus granulosus contactin 0.006 0.0191 0.0248
Schistosoma mansoni titin 0.0045 0.009 0.0118
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0049 0.0117 0.0117
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0127 0.065 0.0845
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0049 0.0117 0.0627
Schistosoma mansoni cell adhesion molecule 0.0034 0.0017 0.0021
Schistosoma mansoni hemicentin 0.0034 0.0017 0.0021
Trichomonas vaginalis cyclins, putative 0.0046 0.0094 0.0387
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Entamoeba histolytica PH domain containing protein kinase, putative 0.0069 0.0253 0.106
Loa Loa (eye worm) TK/RYK protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0069 0.0253 0.106
Brugia malayi Protein kinase domain containing protein 0.0401 0.2527 0.3454
Loa Loa (eye worm) TK protein kinase 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0032 0.0003 0.0003
Giardia lamblia Hypothetical protein 0.0046 0.0094 0.0387
Schistosoma mansoni tyrosine kinase 0.0042 0.0069 0.009
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0086 0.0367 0.0367
Toxoplasma gondii GCC2 and GCC3 domain-containing protein 0.0034 0.001 0.004
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0032 0.0003 0.0005
Brugia malayi Protein kinase domain containing protein 0.0121 0.0609 0.0832
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0038 0.0039 0.0051
Brugia malayi jmjC domain containing protein 0.0035 0.0022 0.003
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0947 0.6271 0.7417
Brugia malayi Immunoglobulin I-set domain containing protein 0.0103 0.0483 0.066
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0127 0.065 0.0845
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.004 0.0051 0.0061
Loa Loa (eye worm) AUR protein kinase 0.0299 0.1833 0.2168
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0108
Echinococcus granulosus tyrosine kinase 0.0117 0.0585 0.0761
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0041 0.0061 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0039 0.0154
Schistosoma mansoni myosin-binding protein-related 0.0034 0.0017 0.0021
Echinococcus granulosus tyrosine kinase 0.0032 0.0003 0.0003
Trypanosoma cruzi cdc2-related kinase 1 0.0121 0.0609 0.2569
Trypanosoma brucei cdc2-related kinase 1 0.0121 0.0609 0.2569
Echinococcus granulosus titin 0.0045 0.009 0.0118
Entamoeba histolytica protein kinase, putative 0.0299 0.1833 0.7756
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0076 0.0313
Echinococcus granulosus cyclin b3 0.0046 0.0094 0.0122
Loa Loa (eye worm) AGC/PKN protein kinase 0.0038 0.0039 0.0046
Loa Loa (eye worm) hypothetical protein 0.0081 0.0335 0.0396
Schistosoma mansoni tyrosine kinase 0.0681 0.4452 0.5793
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0091 0.0124
Echinococcus granulosus cyclins 0.0046 0.0094 0.0122
Trichomonas vaginalis cyclin D, putative 0.0046 0.0094 0.0387
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0003 0.0003
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0043 0.0076 0.0099
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0049 0.0117 0.0153
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0121 0.0609 0.072
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0034 0.0017 0.002
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0121 0.0609 0.2569
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0032 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0377 0.2362 1
Brugia malayi GCC2 and GCC3 family protein 0.0034 0.001 0.0014
Schistosoma mansoni protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0038 0.0039 0.0046
Toxoplasma gondii hypothetical protein 0.0034 0.001 0.004
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0038 0.0039 0.0051
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0032 0.0003 0.0003
Echinococcus granulosus serine:threonine protein kinase N2 0.0038 0.0039 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0091 0.0124
Schistosoma mansoni cyclin B 0.0046 0.0094 0.0122
Schistosoma mansoni protein kinase 0.0183 0.1035 0.1346
Entamoeba histolytica protein kinase domain containing protein 0.0043 0.0076 0.0313
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Trypanosoma cruzi polo-like protein kinase, putative 0.0377 0.2362 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.006 0.0191 0.0261
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Echinococcus granulosus lachesin 0.0045 0.0091 0.0118
Echinococcus granulosus Glutaredoxin protein 5 0.0053 0.0143 0.0185
Brugia malayi serine/threonine-protein kinase plk-2 0.0377 0.2362 0.3229
Echinococcus multilocularis tyrosine kinase 0.0032 0.0003 0.0003
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0049 0.0117 0.0487
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0022 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0034 0.001 0.004
Onchocerca volvulus 0.0042 0.0069 0.0123
Echinococcus multilocularis cyclin dependent kinase 0.0121 0.0609 0.0792
Echinococcus granulosus cyclin dependent kinase 0.0121 0.0609 0.0792
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0049 0.0117 0.0487
Schistosoma mansoni tyrosine kinase 0.0127 0.065 0.0845
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0032 0.0003 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0017 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0039 0.0051
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0039 0.0154
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Entamoeba histolytica cyclin, putative 0.0046 0.0094 0.0387
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0127 0.065 0.0845
Echinococcus multilocularis serine:threonine protein kinase 38 0.0038 0.0039 0.0051
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0051 0.0207
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0064 0.0216 0.0906
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0086 0.0367 0.0252
Schistosoma mansoni protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0003 0.0003
Toxoplasma gondii aldehyde dehydrogenase 0.0036 0.003 0.0148
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0032 0.0003 0.0005
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0052 0.0134 0.0174
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0045 0.0091 0.0162
Echinococcus multilocularis casein kinase ii subunit alpha 0.0183 0.1035 0.1346
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0121 0.0609 0.3312
Onchocerca volvulus 0.0042 0.0069 0.0123
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0108
Echinococcus multilocularis Immunoglobulin 0.0088 0.0383 0.0499
Schistosoma mansoni ephrin receptor 0.0047 0.0102 0.0133
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0034 0.001 0.004
Echinococcus granulosus cyclin dependent kinase 1 0.0121 0.0609 0.0792
Echinococcus multilocularis heat shock protein 70 0.0032 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Loa Loa (eye worm) plexin A 0.0053 0.0141 0.0167
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0043 0.0076 0.0404
Loa Loa (eye worm) TK/EPH protein kinase 0.0212 0.1232 0.1457
Brugia malayi ephrin receptor 1 precursor 0.0099 0.0457 0.0625
Trypanosoma cruzi Protein kinase B 0.0069 0.0253 0.106
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0049 0.0117 0.0487
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0049 0.0117 0.0487
Brugia malayi SH2 domain containing protein 0.0042 0.0069 0.0094
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1491 1 1
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0049 0.0117 0.016
Trypanosoma brucei mitotic cyclin 6 0.0046 0.0094 0.0387
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0022 0.0026
Brugia malayi p70 ribosomal S6 kinase beta 0.0091 0.0401 0.0549
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0003 0.0003
Trypanosoma brucei cdc2-related kinase 3 0.0121 0.0609 0.2569
Echinococcus granulosus protein tyrosine kinase 0.0681 0.4452 0.5793
Trichomonas vaginalis CAMK family protein kinase 0.0377 0.2362 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0041 0.0061 0.025
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0034 0.001 0.004
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0032 0.0003 0.0003
Brugia malayi SH2 domain containing protein 0.0042 0.0069 0.0094
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0032 0.0003 0.0003
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0032 0.0003 0.0003
Echinococcus multilocularis kinase suppressor of Ras 1 0.0032 0.0003 0.0003
Echinococcus multilocularis cyclin dependent kinase 5 0.0121 0.0609 0.0792
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0017 0.002
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0958 0.6351 0.8264
Plasmodium falciparum cysteine repeat modular protein 3 0.0034 0.001 0.004
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0298 0.1821 0.2369
Echinococcus multilocularis serine threonine protein kinase 0.0038 0.0039 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.009 0.0124
Echinococcus multilocularis cyclin dependent kinase 1 0.0121 0.0609 0.0792
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0088 0.0383 0.0499
Echinococcus granulosus mitogen activated protein kinase 3 0.0041 0.0061 0.008
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0032 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0032 0.0003 0.0005
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0032 0.0003 0.0003
Echinococcus granulosus retinal guanylyl cyclase 2 0.0032 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Trichomonas vaginalis CAMK family protein kinase 0.0377 0.2362 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0032 0.0003 0.0003
Echinococcus multilocularis cyclin b3 0.0046 0.0094 0.0122
Trichomonas vaginalis cyclins, putative 0.0046 0.0094 0.0387
Echinococcus granulosus tyrosine protein kinase csk 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK/ABL protein kinase 0.0042 0.0069 0.0082
Brugia malayi Protein kinase domain containing protein 0.0038 0.0039 0.0053
Schistosoma mansoni hypothetical protein 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0042 0.0069 0.009
Echinococcus multilocularis mitogen activated protein kinase 0.0041 0.0061 0.008
Schistosoma mansoni roundabout 0.0045 0.0091 0.0118
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0183 0.1035 0.1224
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0012
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.006 0.0191 0.0248
Plasmodium falciparum conserved protein, unknown function 0.0034 0.001 0.004
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0071 0.0265 0.0313
Entamoeba histolytica protein kinase domain containing protein 0.0183 0.1035 0.4375
Entamoeba histolytica serine/threonine protein kinase, putative 0.0377 0.2362 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.0032 0.0003 0.0003
Echinococcus multilocularis mitogen activated protein kinase 3 0.0041 0.0061 0.008
Echinococcus multilocularis protein KINase family member (kin 25) 0.0032 0.0003 0.0003
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0045 0.0091 0.0118
Echinococcus multilocularis activin receptor type 0.0043 0.0076 0.0099
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Echinococcus multilocularis cyclin dependent kinase 1 0.0121 0.0609 0.0792
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0049 0.0117 0.0487
Loa Loa (eye worm) hypothetical protein 0.0038 0.0039 0.0046
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0003 0.0003
Plasmodium falciparum protein kinase 5 0.0121 0.0609 0.3312
Loa Loa (eye worm) TK protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.1265 0.8454 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0046 0.0094 0.0128
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0438 0.1844
Echinococcus multilocularis endonuclease reverse transcriptase 0.0034 0.001 0.0013
Echinococcus multilocularis roundabout 2 0.0148 0.0794 0.1033
Echinococcus multilocularis c src tyrosine kinase 0.0052 0.0134 0.0174
Brugia malayi plexin A 0.0053 0.0141 0.0193
Echinococcus multilocularis hemicentin 1 0.0045 0.0091 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0039 0.0051
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0377 0.2362 0.2794
Plasmodium falciparum cysteine repeat modular protein 4 0.0034 0.001 0.004
Entamoeba histolytica protein kinase , putative 0.0299 0.1833 0.7756
Trypanosoma cruzi cdc2-related kinase 1 0.0121 0.0609 0.2569
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0609 0.2569
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0091 0.0108
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0711 0.4653 0.6054
Loa Loa (eye worm) hypothetical protein 0.0088 0.0383 0.0453
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0032 0.0003 0.0003
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0052 0.0134 0.0174
Loa Loa (eye worm) SRC-1 0.0127 0.065 0.0768
Echinococcus granulosus NDR protein kinase 0.0038 0.0039 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0947 0.6271 0.8572
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0054 0.0074
Schistosoma mansoni tyrosine kinase 0.0052 0.0134 0.0174
Plasmodium vivax protein kinase Crk2 0.0121 0.0609 0.3312
Trichomonas vaginalis cyclin B3, putative 0.0046 0.0094 0.0387
Entamoeba histolytica casein kinase, putative 0.0183 0.1035 0.4375
Echinococcus granulosus cyclins 0.0046 0.0094 0.0122
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0045 0.009 0.0107
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0049 0.0117 0.0091
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.006 0.0191 0.0226
Echinococcus granulosus integrin linked protein kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0049 0.0117 0.0153
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Schistosoma mansoni protein tyrosine kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0127 0.065 0.0845
Brugia malayi Furin-like cysteine rich region family protein 0.1099 0.7316 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.0558 0.066
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0108
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0003 0.0003
Echinococcus granulosus roundabout 2 0.0148 0.0794 0.1033
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0032 0.0003 0.0003
Brugia malayi hypothetical protein 0.0032 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0299 0.1833 0.2384
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1441 0.9663 1
Entamoeba histolytica cyclin family protein 0.0046 0.0094 0.0387
Trichomonas vaginalis CMGC family protein kinase 0.0121 0.0609 0.2569
Echinococcus multilocularis epidermal growth factor receptor 0.1099 0.7316 0.9518
Echinococcus granulosus ephrin type A receptor 4 A 0.0207 0.1197 0.1558
Schistosoma mansoni tyrosine kinase 0.1099 0.7316 0.9518
Echinococcus multilocularis transfer RNA-Thr 0.0032 0.0003 0.0003
Echinococcus granulosus protein kinase C gamma type 0.0038 0.0039 0.0051
Echinococcus multilocularis integrin linked protein kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0036 0.003 0.0038
Trichomonas vaginalis cyclin B, putative 0.0046 0.0094 0.0387
Trypanosoma cruzi cdc2-related kinase 3 0.0121 0.0609 0.2569
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Brugia malayi Guanylyl cyclase protein 23 0.0032 0.0003 0.0003
Entamoeba histolytica cell division protein kinase 2, putative 0.0121 0.0609 0.2569
Onchocerca volvulus 0.0042 0.0069 0.0123
Echinococcus multilocularis tyrosine protein kinase csk 0.0032 0.0003 0.0003
Echinococcus granulosus roundabout 2 0.006 0.0191 0.0248
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0042 0.0069 0.0282
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0299 0.1833 0.7756
Onchocerca volvulus 0.0801 0.5271 0.9362
Schistosoma mansoni nephrin 0.0122 0.062 0.0806
Echinococcus multilocularis 0.0326 0.2018 0.2625
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0067 0.0088
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0438 0.1844
Echinococcus granulosus tyrosine protein kinase Src42A 0.0127 0.065 0.0845
Echinococcus granulosus tyrosine protein kinase Fyn 0.0127 0.065 0.0845
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.1035 0.4375
Echinococcus multilocularis roundabout 2 0.006 0.0191 0.0248
Schistosoma mansoni serine/threonine kinase 0.0038 0.0039 0.0051
Loa Loa (eye worm) hypothetical protein 0.0141 0.0745 0.0881
Echinococcus granulosus kinase suppressor of Ras 1 0.0032 0.0003 0.0003
Brugia malayi SRC-1 0.0127 0.065 0.0888
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.1035 0.4375
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Echinococcus granulosus twitchin 0.0119 0.0594 0.0773
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0108
Entamoeba histolytica cell division protein kinase 2, putative 0.0121 0.0609 0.2569
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Trypanosoma cruzi casein kinase II, putative 0.0183 0.1035 0.4375
Loa Loa (eye worm) TK/ACK protein kinase 0.0032 0.0003 0.0003
Echinococcus granulosus cyclins 0.0046 0.0094 0.0122
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0091 0.0401 0.0475
Entamoeba histolytica hypothetical protein 0.0034 0.001 0.0031
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0038 0.0039 0.0051
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0032 0.0003 0.0003
Plasmodium falciparum cyclin 0.0046 0.0094 0.0499
Schistosoma mansoni cell adhesion molecule 0.0128 0.0657 0.0855
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0022 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Echinococcus granulosus peroxidasin 0.0045 0.0091 0.0118
Echinococcus multilocularis nervana 2 0.0053 0.0143 0.0185
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) projectin 0.0034 0.0017 0.002
Toxoplasma gondii kringle domain-containing protein 0.0034 0.001 0.004
Echinococcus granulosus Immunoglobulin 0.0088 0.0383 0.0499
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0091 0.0124
Schistosoma mansoni protein kinase 0.0032 0.0003 0.0003
Echinococcus granulosus activated cdc42 kinase 1 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK protein kinase 0.0108 0.0518 0.0613
Loa Loa (eye worm) protein kinase domain-containing protein 0.0032 0.0003 0.0003
Echinococcus multilocularis tyrosine kinase 0.0042 0.0069 0.009
Schistosoma mansoni ephrin receptor 0.0173 0.0967 0.1259
Treponema pallidum fructose-bisphosphate aldolase 0.0175 0.0981 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0003 0.0003
Brugia malayi hypothetical protein 0.0103 0.0483 0.066
Brugia malayi Protein kinase domain containing protein 0.0944 0.6252 0.8545
Entamoeba histolytica protein kinase, putative 0.0299 0.1833 0.7756
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0003 0.0003
Brugia malayi protein-tyrosine kinase 0.0117 0.0585 0.0799
Loa Loa (eye worm) hypothetical protein 0.0034 0.0017 0.002
Trypanosoma cruzi aurora B kinase, putative 0.0299 0.1833 0.7756
Echinococcus granulosus tyrosine protein kinase Srms 0.0042 0.0069 0.009
Echinococcus multilocularis neuroglian 0.006 0.0191 0.0248
Echinococcus multilocularis activated cdc42 kinase 1 0.0032 0.0003 0.0003
Echinococcus multilocularis Immunoglobulin 0.0088 0.0383 0.0499
Brugia malayi Fibronectin type III domain containing protein 0.0103 0.0483 0.066
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.006 0.0191 0.0248
Leishmania major protein kinase, putative 0.0043 0.0076 0.0313
Loa Loa (eye worm) hypothetical protein 0.0045 0.0086 0.0101
Schistosoma mansoni neuroglian 0.006 0.0191 0.0248
Brugia malayi Receptor family ligand binding region containing protein 0.0032 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.1035 0.4375
Brugia malayi hypothetical protein 0.0042 0.0069 0.0094
Echinococcus multilocularis tyrosine protein kinase 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0127 0.065 0.0845
Schistosoma mansoni protein kinase 0.0043 0.0076 0.0099
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) AUR protein kinase 0.0299 0.1833 0.2168
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0108
Schistosoma mansoni cell adhesion molecule 0.0034 0.0017 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0299 0.1833 0.7756
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0377 0.2362 0.3073
Entamoeba histolytica protein kinase 2, putative 0.0064 0.0216 0.0906
Echinococcus multilocularis FL cytokine receptor 0.0032 0.0003 0.0003
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0049 0.0117 0.0487
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.004 0.0051 0.0067
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0049 0.0117 0.0487
Echinococcus multilocularis cyclin B3 1 0.0046 0.0094 0.0122
Onchocerca volvulus Serine\/threonine kinase homolog 0.0377 0.2362 0.4196
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0377 0.2362 1
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0039 0.0051
Echinococcus granulosus protein kinase c epsilon type 0.0038 0.0039 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Loa Loa (eye worm) hypothetical protein 0.0368 0.2305 0.2726
Entamoeba histolytica protein kinase, putative 0.0108 0.0518 0.2185
Loa Loa (eye worm) TK/ROR protein kinase 0.0052 0.0139 0.0165
Schistosoma mansoni serine/threonine-protein kinase 0.0069 0.0253 0.0329
Trypanosoma cruzi cdc2-related kinase 3 0.0121 0.0609 0.2569
Brugia malayi Hr1 repeat family protein 0.0038 0.0039 0.0053
Echinococcus granulosus tyrosine protein kinase HCK 0.0108 0.0518 0.0674
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Trypanosoma cruzi cyclin 6, putative 0.0046 0.0094 0.0387
Echinococcus granulosus microtubule associated protein 2 0.1153 0.7686 1
Echinococcus granulosus insulin receptor 0.0944 0.6252 0.8134
Schistosoma mansoni microtubule-associated protein tau 0.1153 0.7686 1
Echinococcus multilocularis protein kinase 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0032 0.0003 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0091 0.0124
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0051 0.0207
Schistosoma mansoni aldehyde dehydrogenase 0.0036 0.003 0.0038
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Echinococcus granulosus epidermal growth factor receptor 0.0743 0.4875 0.6343
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Brugia malayi Peroxidasin 0.0045 0.0091 0.0124
Echinococcus granulosus tyrosine protein kinase Lyn 0.0138 0.0723 0.0941
Mycobacterium ulcerans aldehyde dehydrogenase 0.0036 0.003 0.003
Echinococcus granulosus titin 0.0045 0.009 0.0118
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0061 0.025
Echinococcus granulosus protein kinase 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0032 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0096 0.0438 0.0598
Schistosoma mansoni tyrosine kinase 0.0711 0.4653 0.6054
Loa Loa (eye worm) hypothetical protein 0.0103 0.0483 0.0572
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0032 0.0003 0.0003
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0298 0.1821 0.2369
Echinococcus multilocularis insulin receptor 0.0944 0.6252 0.8134
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0085 0.0362 0.0471
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase Src42A 0.0085 0.0362 0.0471
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.1035 0.4375
Trichomonas vaginalis cyclin A, putative 0.0046 0.0094 0.0387
Entamoeba histolytica protein kinase domain containing protein 0.0299 0.1833 0.7756
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0032 0.0003 0.0003
Brugia malayi Tyrosine-protein kinase abl-1 0.0052 0.0134 0.0183
Giardia lamblia Kinase, CMGC CK2 0.0183 0.1035 0.4375
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0034 0.0017 0.0029
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0042 0.0069 0.009
Echinococcus multilocularis peroxidasin 0.0045 0.0091 0.0118
Echinococcus multilocularis hemicentin 1 0.0045 0.0091 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Schistosoma mansoni protein kinase 0.0032 0.0003 0.0003
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0299 0.1833 0.7756
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0039 0.0051
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0012
Schistosoma mansoni jumonji domain containing protein 0.0035 0.0022 0.0028
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) TK protein kinase 0.0032 0.0003 0.0003
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0046 0.0094 0.0387
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.004 0.0051 0.007
Entamoeba histolytica tyrosin kinase, putative 0.0041 0.0058 0.0237
Schistosoma mansoni serine/threonine RGC 0.0032 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0043 0.0075 0.0308
Schistosoma mansoni protein kinase 0.0043 0.0076 0.0099
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0111
Schistosoma mansoni tyrosine protein kinase 0.0032 0.0003 0.0003
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0049 0.0117 0.0487
Echinococcus multilocularis plexin a4 0.0053 0.0141 0.0184
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.1035 0.4375
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0127 0.065 0.0845
Schistosoma mansoni hypothetical protein 0.0034 0.0017 0.0021
Schistosoma mansoni tyrosine kinase 0.0743 0.4875 0.6343
Onchocerca volvulus 0.0032 0.0003 0.0005
Echinococcus multilocularis cyclins 0.0046 0.0094 0.0122
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0045 0.0091 0.0118
Schistosoma mansoni hypothetical protein 0.0034 0.001 0.0013
Onchocerca volvulus 0.0032 0.0003 0.0005
Echinococcus granulosus activated cdc42 kinase 1 0.0032 0.0003 0.0003
Echinococcus granulosus nervana 2 0.0053 0.0143 0.0185
Echinococcus multilocularis microtubule associated protein 2 0.1153 0.7686 1
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0377 0.2362 1
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0061 0.025
Echinococcus multilocularis cyclin B 0.0046 0.0094 0.0122
Echinococcus granulosus endonuclease reverse transcriptase 0.0034 0.001 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0438 0.1844
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0133 0.0694 0.0821
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0032 0.0003 0.0005
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0032 0.0003 0.0003
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0043 0.0076 0.0099
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0035 0.0022 0.0028
Echinococcus multilocularis cyclins 0.0046 0.0094 0.0122
Schistosoma mansoni plexin 0.0045 0.0086 0.0111
Brugia malayi Immunoglobulin I-set domain containing protein 0.006 0.0191 0.0261
Loa Loa (eye worm) hypothetical protein 0.0133 0.0694 0.0821
Onchocerca volvulus 0.0042 0.0069 0.0123
Schistosoma mansoni atypical protein kinase C 0.0038 0.0039 0.0051
Echinococcus multilocularis serine:threonine protein kinase N2 0.0038 0.0039 0.0051
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0041 0.0061 0.025
Giardia lamblia Kinase, CMGC CDK 0.0121 0.0609 0.2569
Giardia lamblia G2/mitotic-specific cyclin B 0.0046 0.0094 0.0387
Echinococcus granulosus c src tyrosine kinase 0.0052 0.0134 0.0174
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0108
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0053 0.0143 0.0185
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0117 0.0585 0.0761
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0036 0.003 0.0115
Echinococcus granulosus activin receptor type 0.0043 0.0076 0.0099
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0017 0.0023
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.006 0.0191 0.0248
Echinococcus granulosus neuroglian 0.006 0.0191 0.0248
Echinococcus granulosus tyrosine protein kinase ABL1 0.0042 0.0069 0.009
Echinococcus granulosus aurora kinase A 0.0299 0.1833 0.2384
Echinococcus multilocularis cyclins 0.0046 0.0094 0.0122
Echinococcus granulosus cyclins 0.0046 0.0094 0.0122
Toxoplasma gondii AGC kinase 0.0091 0.0401 0.2179
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0039 0.0051
Echinococcus granulosus neuroglian 0.0108 0.052 0.0676
Onchocerca volvulus Tyrosine kinase homolog 0.0853 0.563 1
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0743 0.4875 0.6343
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0111
Leishmania major casein kinase II, putative 0.0183 0.1035 0.4375
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0438 0.1844
Trichomonas vaginalis cyclin D, putative 0.0046 0.0094 0.0387
Plasmodium vivax protein kinase, putative 0.0043 0.0078 0.0414
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0059 0.0186 0.0242
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0076 0.0313
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0032 0.0003 0.0003
Onchocerca volvulus 0.0045 0.0086 0.0152
Loa Loa (eye worm) TK protein kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis tyrosine protein kinase Abl 0.0052 0.0134 0.0174
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0086 0.0367 0.035
Giardia lamblia Kinase, CMGC CDK 0.0121 0.0609 0.2569
Loa Loa (eye worm) hypothetical protein 0.0103 0.0483 0.0572
Trichomonas vaginalis cyclin B, putative 0.0046 0.0094 0.0387
Echinococcus multilocularis serine:threonine protein kinase N2 0.0038 0.0039 0.0051
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0049 0.0117 0.0627
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Schistosoma mansoni cell adhesion molecule 0.006 0.0191 0.0248
Brugia malayi Cyclin, N-terminal domain containing protein 0.0046 0.0094 0.0128
Trichomonas vaginalis cyclin B, putative 0.0046 0.0094 0.0387
Entamoeba histolytica cyclin, putative 0.0046 0.0094 0.0387
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0127 0.065 0.0845
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0039 0.0154
Echinococcus multilocularis protein kinase c iota type 0.0038 0.0039 0.0051
Brugia malayi Casein kinase II, alpha chain 0.0183 0.1035 0.1414
Trypanosoma brucei aurora B kinase 0.0299 0.1833 0.7756
Brugia malayi Plexin repeat family protein 0.0045 0.0086 0.0117
Schistosoma mansoni lipoxygenase 0.0059 0.0186 0.0242
Giardia lamblia CEGP1 protein 0.0034 0.001 0.0031
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0064 0.0216 0.0282
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0091 0.0108
Entamoeba histolytica protein kinase, putative 0.0091 0.0401 0.169
Loa Loa (eye worm) AGC/AKT protein kinase 0.0096 0.0438 0.0518
Echinococcus granulosus cyclin dependent kinase 5 0.0121 0.0609 0.0792
Brugia malayi Immunoglobulin I-set domain containing protein 0.006 0.0191 0.0261
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0064 0.0216 0.0282
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0743 0.4875 0.6343
Echinococcus granulosus serine threonine protein kinase nrc 0.0064 0.0216 0.0282
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0038 0.0039 0.0046
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0064 0.0216 0.1169
Entamoeba histolytica PH domain containing protein kinase, putative 0.0069 0.0253 0.106
Plasmodium falciparum protein kinase, putative 0.0043 0.0076 0.0404
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0032 0.0003 0.0003
Echinococcus multilocularis Glutaredoxin protein 5 0.0053 0.0143 0.0185
Echinococcus multilocularis cyclins 0.0046 0.0094 0.0122
Plasmodium vivax unspecified product 0.0183 0.1035 0.564
Echinococcus granulosus natriuretic peptide receptor 1 0.0032 0.0003 0.0003
Echinococcus granulosus mitogen activated protein kinase 0.0041 0.0061 0.008
Echinococcus granulosus cyclin B 0.0046 0.0094 0.0122
Echinococcus granulosus cyclins 0.0046 0.0094 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0377 0.2362 1
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis tyrosine protein kinase csk 0.0032 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0944 0.6252 0.8134
Echinococcus multilocularis transfer RNA-Phe 0.0034 0.0017 0.0021
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0059 0.0186 0.0242
Brugia malayi GCC2 and GCC3 family protein 0.0034 0.001 0.0014
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0046 0.0094 0.0122
Schistosoma mansoni tyrosine kinase 0.0052 0.0134 0.0174
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0034 0.0017 0.0021
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Brugia malayi hypothetical protein 0.0032 0.0003 0.0003
Echinococcus multilocularis nervana 2 0.0053 0.0143 0.0185
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0377 0.2362 0.3073
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0038 0.0039 0.0051
Onchocerca volvulus 0.0032 0.0003 0.0005
Schistosoma mansoni titin 0.0034 0.0017 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0032 0.0003 0.0003
Echinococcus granulosus Protein kinase C brain isozyme 0.0038 0.0039 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0017 0.0023
Entamoeba histolytica protein kinase, putative 0.0096 0.0438 0.1844
Echinococcus multilocularis rac serine:threonine kinase 0.0069 0.0253 0.0329
Giardia lamblia Aurora kinase 0.0299 0.1833 0.7756
Loa Loa (eye worm) CAMK protein kinase 0.0045 0.009 0.0107
Echinococcus granulosus casein kinase ii subunit alpha 0.0183 0.1035 0.1346
Schistosoma mansoni nephrin 0.006 0.0191 0.0248
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0049 0.0117 0.0627
Echinococcus granulosus tyrosine protein kinase csk 0.0032 0.0003 0.0003
Brugia malayi serine/threonine protein kinase 6 0.0299 0.1833 0.2505
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0032 0.0003 0.0003
Echinococcus granulosus epidermal growth factor receptor 0.1099 0.7316 0.9518
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0038 0.0039 0.0154
Echinococcus multilocularis protein kinase 0.0032 0.0003 0.0003
Brugia malayi Protein kinase domain containing protein 0.0689 0.4505 0.6158
Echinococcus multilocularis titin 0.0045 0.009 0.0118
Schistosoma mansoni septate junction protein 0.0045 0.0091 0.0118
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0127 0.065 0.0845
Echinococcus granulosus plexin a4 0.0053 0.0141 0.0184
Onchocerca volvulus 0.0045 0.009 0.0161
Brugia malayi GCC2 and GCC3 family protein 0.0034 0.001 0.0014
Schistosoma mansoni tyrosine kinase 0.0078 0.0313 0.0408
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.004 0.0051 0.0207
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Giardia lamblia Kinase, PLK 0.0377 0.2362 1
Schistosoma mansoni protein kinase 0.0032 0.0003 0.0003
Trichomonas vaginalis cyclin B, putative 0.0046 0.0094 0.0387
Brugia malayi jmjC domain containing protein 0.0035 0.0022 0.003
Brugia malayi GCC2 and GCC3 family protein 0.0034 0.001 0.0014
Schistosoma mansoni serine/threonine-protein kinase 0.0069 0.0253 0.0329
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0052 0.0139 0.0181
Trypanosoma brucei protein kinase, putative 0.0041 0.0061 0.025
Entamoeba histolytica hypothetical protein 0.0034 0.001 0.0031
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0299 0.1833 0.2384
Giardia lamblia Fructose-bisphosphate aldolase 0.0175 0.0981 0.4146
Onchocerca volvulus 0.0032 0.0003 0.0005
Entamoeba histolytica protein kinase, putative 0.0096 0.0438 0.1844
Trypanosoma brucei Casein kinase II 0.0183 0.1035 0.4375
Brugia malayi Protein kinase domain containing protein 0.0038 0.0039 0.0053
Brugia malayi MAP kinase sur-1 0.0041 0.0061 0.0084
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Echinococcus granulosus retinal guanylyl cyclase 2 0.0032 0.0003 0.0003
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.006 0.0191 0.0248
Echinococcus multilocularis raf serine:threonine protein kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis natriuretic peptide receptor 1 0.0032 0.0003 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0377 0.2362 0.3073
Brugia malayi Protein kinase domain containing protein 0.0042 0.0069 0.0094
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Plasmodium falciparum serine/threonine protein kinase, putative 0.0299 0.1833 1
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.1035 0.4375
Echinococcus granulosus nervana 2 0.0053 0.0143 0.0185
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0052 0.0134 0.0174
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0069 0.0082
Onchocerca volvulus 0.0034 0.001 0.0018
Echinococcus granulosus cyclin B3 1 0.0046 0.0094 0.0122
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.004 0.0051 0.0067
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0032 0.0003 0.0003
Echinococcus multilocularis tyrosine protein kinase HCK 0.0108 0.0518 0.0674
Echinococcus granulosus Down syndrome cell adhesion molecule 0.004 0.0054 0.0071
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0032 0.0003 0.0003
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0299 0.1833 0.7756
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0017 0.002
Echinococcus granulosus receptor type guanylyl cyclase 0.0032 0.0003 0.0003
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0121 0.0609 0.2569
Entamoeba histolytica hypothetical protein, conserved 0.0034 0.001 0.0031
Giardia lamblia Cyclin A 0.0046 0.0094 0.0387
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0032 0.0003 0.0003
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0041 0.0061 0.025
Trypanosoma cruzi cyclin, putative 0.0046 0.0094 0.0387
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0032 0.0003 0.0003
Echinococcus multilocularis cyclins 0.0046 0.0094 0.0122
Echinococcus granulosus tyrosine kinase 0.0042 0.0069 0.009
Schistosoma mansoni protein kinase 0.0299 0.1833 0.2384
Plasmodium falciparum cysteine repeat modular protein 1 0.0034 0.001 0.004
Schistosoma mansoni protein kinase 0.0032 0.0003 0.0003
Echinococcus multilocularis lachesin 0.0045 0.0091 0.0118
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0036 0.003 0.0038
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase Fyn 0.0127 0.065 0.0845
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0042 0.0069 0.009
Schistosoma mansoni tyrosine kinase 0.0944 0.6252 0.8134
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0034 0.001 0.004
Trypanosoma cruzi cyclin, putative 0.0046 0.0094 0.0387
Trichomonas vaginalis CAMK family protein kinase 0.0377 0.2362 1
Brugia malayi protein kinase C II. 0.0038 0.0039 0.0053
Echinococcus multilocularis ephrin type A receptor 4 A 0.0207 0.1197 0.1558
Echinococcus multilocularis tyrosine protein kinase Srms 0.0117 0.0585 0.0761
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0958 0.6351 0.8264
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0039 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0039 0.0051
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0022 0.0028
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.004 0.0054 0.0071
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Echinococcus granulosus roundabout 2 0.006 0.0191 0.0248
Loa Loa (eye worm) hypothetical protein 0.0034 0.001 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0675 0.2851
Giardia lamblia Hypothetical protein 0.0034 0.001 0.0031
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0088 0.0383 0.0453
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0041 0.0061 0.025
Loa Loa (eye worm) TK/EGFR protein kinase 0.1099 0.7316 0.8653
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0017 0.0023
Trichomonas vaginalis cyclins, putative 0.0046 0.0094 0.0387
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0038 0.0039 0.0046
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.004 0.0051 0.0067
Echinococcus multilocularis tyrosine protein kinase pr2 0.0032 0.0003 0.0003
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0299 0.1833 0.2384
Trichomonas vaginalis AGC family protein kinase 0.0299 0.1833 0.7756
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.004 0.0051 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0609 0.0792
Echinococcus granulosus serine/threonine protein kinase 0.0069 0.0253 0.0329
Brugia malayi Protein kinase domain containing protein 0.0032 0.0003 0.0003
Plasmodium falciparum casein kinase 2, alpha subunit 0.0183 0.1035 0.564
Echinococcus granulosus tyrosine protein kinase 0.0032 0.0003 0.0003
Echinococcus granulosus tyrosine protein kinase Fyn 0.0127 0.065 0.0845
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0121 0.0609 0.072
Brugia malayi Tyrosine-protein kinase PR2 0.0032 0.0003 0.0003
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0121 0.0609 0.0792
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0088 0.0383 0.0499
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0041 0.0061 0.025
Schistosoma mansoni titin 0.0045 0.0091 0.0118
Echinococcus granulosus tyrosine protein kinase Blk 0.0117 0.0585 0.0761
Loa Loa (eye worm) hypothetical protein 0.0088 0.0383 0.0453
Loa Loa (eye worm) hypothetical protein 0.0032 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0094 0.0387
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0046 0.0094 0.0122
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0032 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0175 0.0981 0.4146
Echinococcus multilocularis tyrosine protein kinase Blk 0.0117 0.0585 0.0761
Echinococcus multilocularis epidermal growth factor receptor 0.0743 0.4875 0.6343
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0076 0.0313
Schistosoma mansoni cyclins 0.0046 0.0094 0.0122
Toxoplasma gondii hypothetical protein 0.0035 0.0018 0.0085
Brugia malayi Protein kinase domain containing protein 0.0042 0.0069 0.0094
Brugia malayi C-terminal src kinase protein 1 0.0032 0.0003 0.0003
Echinococcus multilocularis roundabout 2 0.006 0.0191 0.0248
Echinococcus multilocularis contactin neuroglian septate junction protein 0.006 0.0191 0.0248
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0041 0.0061 0.025
Loa Loa (eye worm) AGC/NDR protein kinase 0.0038 0.0039 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0061 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0609 0.0792
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0088 0.0383 0.0499
Schistosoma mansoni tyrosine kinase 0.0032 0.0003 0.0003
Brugia malayi protein unc-22 0.0045 0.009 0.0124

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3.1 nM Concentration required to inhibit proliferation of Human lung carcinoma NCI-H460 cell line ChEMBL. 11294380
IC50 (functional) = 3.1 nM Concentration required to inhibit proliferation of Human lung carcinoma NCI-H460 cell line ChEMBL. 11294380
IC50 (functional) = 3.3 nM Concentration required to inhibit proliferation of multidrug resistant Human colon carcinoma HCT-15 cell line ChEMBL. 11294380
IC50 (functional) = 3.3 nM Concentration required to inhibit proliferation of multidrug resistant Human colon carcinoma HCT-15 cell line ChEMBL. 11294380
IC50 (functional) = 1.4 uM Concentration required to inhibit polymerization of tubulin ChEMBL. 11294380
IC50 (functional) = 1.4 uM Concentration required to inhibit polymerization of tubulin ChEMBL. 11294380
Inhibition (binding) = 63 % Percent inhibition of colchicine(5 microM) binding to tubulin(10 microM) at the compound concentration of 5 microM ChEMBL. 11294380
Inhibition (binding) = 63 % Percent inhibition of colchicine(5 microM) binding to tubulin(10 microM) at the compound concentration of 5 microM ChEMBL. 11294380
Inhibition (binding) = 95 % Percent inhibition of colchicine(5 microM) binding to tubulin(10 microM) at the compound concentration of 50 microM ChEMBL. 11294380
Inhibition (binding) = 95 % Percent inhibition of colchicine(5 microM) binding to tubulin(10 microM) at the compound concentration of 50 microM ChEMBL. 11294380

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 11294380

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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