Detailed information for compound 407048

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1398.31 | Formula: C62H80IN17O13
  • H donors: 15 H acceptors: 13 LogP: -1.26 Rotable bonds: 44
    Rule of 5 violations (Lipinski): 4
  • SMILES: NC(=O)C[C@@H](C(=O)N[C@H](C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1ccc(c(c1)I)O)CCCN=C(N)N)CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)NC(=O)C)Cc1ccccc1)CCC(=O)N
  • InChi: 1S/C62H80IN17O13/c1-34(81)73-45(31-36-18-21-39(22-19-36)52(85)38-13-6-3-7-14-38)56(89)78-46(30-35-11-4-2-5-12-35)57(90)74-42(23-25-50(64)83)55(88)79-47(33-51(65)84)58(91)76-43(16-9-27-72-62(69)70)60(93)80-28-10-17-48(80)59(92)75-41(15-8-26-71-61(67)68)54(87)77-44(53(66)86)32-37-20-24-49(82)40(63)29-37/h2-7,11-14,18-22,24,29,41-48,82H,8-10,15-17,23,25-28,30-33H2,1H3,(H2,64,83)(H2,65,84)(H2,66,86)(H,73,81)(H,74,90)(H,75,92)(H,76,91)(H,77,87)(H,78,89)(H,79,88)(H4,67,68,71)(H4,69,70,72)/t41-,42-,43-,44-,45-,46-,47-,48+/m0/s1
  • InChiKey: RQMATGFLPHRUQG-GEUZJVICSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens arginine vasopressin receptor 1A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni neurotransmitter gated ion channel 0.0032 0.0001 0.0002
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0059 0.0082 0.0205
Echinococcus granulosus signal transduction protein lnk realted 0.0075 0.0129 0.0323
Loa Loa (eye worm) hypothetical protein 0.0036 0.0015 0.0038
Echinococcus granulosus NCK adaptor protein 0.0148 0.0345 0.0867
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0224 0.0573 0.1367
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0123 0.1535
Schistosoma mansoni tyrosine kinase 0.0097 0.0195 0.0466
Loa Loa (eye worm) hypothetical protein 0.0084 0.0157 0.0394
Schistosoma mansoni nuclear hormone receptor 0.0075 0.013 0.031
Brugia malayi steroid hormone receptor 0.0159 0.038 0.1692
Onchocerca volvulus 0.0032 0.0001 0.0014
Echinococcus multilocularis signal transduction protein lnk realted 0.0075 0.0129 0.0129
Schistosoma mansoni neuropeptide receptor 0.0224 0.0573 0.1367
Echinococcus granulosus g-protein coupled receptor 0.0224 0.0573 0.1439
Onchocerca volvulus 0.0224 0.0573 0.9047
Onchocerca volvulus 0.0036 0.0015 0.0237
Echinococcus granulosus nostrin 0.0073 0.0123 0.031
Schistosoma mansoni peptidylglycine monooxygenase 0.0762 0.2171 0.5177
Brugia malayi nuclear receptor NHR-88 0.0075 0.013 0.0579
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0215 0.0545 0.1369
Echinococcus multilocularis tyrosine protein kinase shark 0.0097 0.0195 0.0195
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0073 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.008 0.0146 0.0347
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0205 0.0516 0.1295
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0159 0.038 0.1692
Echinococcus granulosus rhodopsin orphan GPCR 0.0224 0.0573 0.1439
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0059 0.0082 0.0194
Schistosoma mansoni nAChR subunit 0.0059 0.0082 0.0194
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0043
Brugia malayi hypothetical protein 0.0084 0.0157 0.0698
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0059 0.0082 0.0205
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0224 0.0573 0.1367
Schistosoma mansoni hypothetical protein 0.0075 0.0129 0.0307
Onchocerca volvulus 0.0037 0.0017 0.0272
Brugia malayi chromobox protein homolog 3 0.0039 0.0023 0.0102
Loa Loa (eye worm) TYRA-2 protein 0.0224 0.0573 0.1439
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0123 0.0549
Echinococcus granulosus tumor protein p63 0.0338 0.0912 0.2289
Echinococcus multilocularis rhodopsin orphan GPCR 0.0224 0.0573 0.0573
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0059 0.0082 0.0363
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Schistosoma mansoni alpha-1 adrenergic receptor 0.0224 0.0573 0.1367
Schistosoma mansoni growth factor receptor-bound protein 0.0148 0.0345 0.0824
Echinococcus granulosus SH2 motif 0.0075 0.0129 0.0323
Schistosoma mansoni thyroid hormone receptor 0.0159 0.038 0.0906
Echinococcus granulosus nAChR subunit 0.0059 0.0082 0.0205
Loa Loa (eye worm) ACC-1 protein 0.0059 0.0082 0.0205
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0804 1
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0467 0.5817
Echinococcus multilocularis peregrin 0.0063 0.0093 0.0093
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0075 0.0129 0.0307
Giardia lamblia PHD finger protein 15 0.0063 0.0093 0.1153
Entamoeba histolytica hypothetical protein 0.0073 0.0123 0.0975
Onchocerca volvulus Protein ultraspiracle homolog 0.0159 0.038 0.5998
Schistosoma mansoni biogenic amine receptor 0.0224 0.0573 0.1367
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0032 0.0001 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0047 0.0118
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0059 0.0082 0.0194
Onchocerca volvulus 0.0075 0.013 0.2052
Echinococcus multilocularis Niemann Pick C1 protein 0.011 0.0233 0.0233
Schistosoma mansoni biogenic amine receptor 0.0224 0.0573 0.1367
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Echinococcus granulosus tyrosine protein kinase Lyn 0.0605 0.1704 0.4278
Onchocerca volvulus 0.0075 0.0129 0.2033
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Brugia malayi beta-lactamase 0.0037 0.0017 0.0077
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0123 0.1535
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0224 0.0573 0.1367
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Echinococcus multilocularis Niemann Pick C1 protein 0.0157 0.0372 0.0372
Loa Loa (eye worm) hypothetical protein 0.0084 0.0157 0.0394
Echinococcus multilocularis epidermal growth factor receptor 0.0154 0.0364 0.0364
Giardia lamblia Fructose-bisphosphate aldolase 0.0302 0.0804 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0093 0.3318
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Entamoeba histolytica hypothetical protein 0.0073 0.0123 0.0975
Echinococcus granulosus c src tyrosine kinase 0.017 0.0412 0.1034
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0059 0.0082 0.0363
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0059 0.0082 0.0363
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0059 0.0082 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0123 0.1535
Entamoeba histolytica protein kinase, putative 0.0075 0.0129 0.1018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Trichomonas vaginalis replication factor C large subunit, putative 0.0031 0.00000034603 0.0000043061
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0017 0.0499
Schistosoma mansoni jumonji/arid domain-containing protein 0.0076 0.0132 0.0314
Loa Loa (eye worm) hypothetical protein 0.0159 0.038 0.0954
Loa Loa (eye worm) DOMON domain-containing protein 0.0146 0.034 0.0854
Loa Loa (eye worm) hypothetical protein 0.0159 0.038 0.0954
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0075 0.013 0.2052
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Echinococcus multilocularis neuropeptide FF receptor 2 0.0224 0.0573 0.0573
Onchocerca volvulus 0.0075 0.0129 0.2033
Onchocerca volvulus 0.0146 0.034 0.537
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0605 0.1704 0.1704
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Brugia malayi beta-lactamase family protein 0.0037 0.0017 0.0077
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0761 0.9474
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0084 0.0157 0.0157
Brugia malayi neuropeptide F receptor 0.0224 0.0573 0.2552
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0059 0.0082 0.0205
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0224 0.0573 0.1439
Brugia malayi Dopamine receptor 0.0224 0.0573 0.2552
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0017 0.0616
Schistosoma mansoni apoptosis stimulating of P53 0.0073 0.0123 0.0294
Schistosoma mansoni tyrosine kinase 0.0268 0.0704 0.1678
Echinococcus granulosus glycine receptor subunit beta 0.0059 0.0082 0.0205
Echinococcus multilocularis neuropeptide Y receptor 0.0224 0.0573 0.0573
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0159 0.038 0.1692
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0148 0.0345 0.0867
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0224 0.0573 0.0573
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Trypanosoma cruzi major cysteine proteinase, putative 0.0033 0.0004 0.0147
Echinococcus multilocularis serotonin transporter 0.0075 0.013 0.013
Echinococcus multilocularis g-protein coupled receptor 0.0224 0.0573 0.0573
Schistosoma mansoni nuclear receptor 0.0075 0.013 0.031
Echinococcus granulosus nuclear receptor nhr 48 0.0075 0.013 0.0326
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0123 0.0549
Echinococcus granulosus src region 0.0073 0.0123 0.031
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0017 0.0041
Loa Loa (eye worm) hypothetical protein 0.0039 0.0023 0.0057
Onchocerca volvulus 0.0073 0.0123 0.1946
Loa Loa (eye worm) hypothetical protein 0.0036 0.0015 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0159 0.038 0.0954
Schistosoma mansoni nuclear hormone receptor 0.0075 0.013 0.031
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0075 0.0129 0.0323
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Echinococcus granulosus Spectrin alpha actinin 0.0073 0.0123 0.031
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0159 0.038 0.0954
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0159 0.038 0.0954
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Echinococcus granulosus serotonin receptor 0.0224 0.0573 0.1439
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0017 0.0043
Echinococcus granulosus fch and double sh3 domains protein 2 0.0073 0.0123 0.031
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0605 0.1704 0.1704
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0036 0.0015 0.0425
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0059 0.0082 0.0082
Echinococcus granulosus thymidylate synthase 0.0089 0.0171 0.043
Echinococcus multilocularis fmrfamide receptor 0.0224 0.0573 0.0573
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0224 0.0573 0.1367
Echinococcus multilocularis lysine specific demethylase 5A 0.0076 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0159 0.038 0.0954
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0061 0.0272
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni hypothetical protein 0.0224 0.0573 0.1367
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0084 0.0157 0.0374
Onchocerca volvulus 0.0224 0.0573 0.9047
Echinococcus multilocularis neuropeptide receptor 0.0224 0.0573 0.0573
Loa Loa (eye worm) steroid hormone receptor 0.0159 0.038 0.0954
Schistosoma mansoni vav2 0.0075 0.0129 0.0307
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0017 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0224 0.0573 0.0573
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.008 0.0146 0.0146
Schistosoma mansoni tyrosine kinase 0.0131 0.0297 0.0709
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0043 0.0035 0.0155
Brugia malayi G protein-coupled receptor F59B2.13 0.0224 0.0573 0.2552
Schistosoma mansoni nuclear receptor 0.0075 0.013 0.031
Loa Loa (eye worm) hypothetical protein 0.0036 0.0015 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0224 0.0573 0.0573
Schistosoma mansoni tyrosine kinase 0.0154 0.0364 0.0867
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0075 0.0129 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0123 0.1535
Schistosoma mansoni hypothetical protein 0.0037 0.0017 0.0041
Loa Loa (eye worm) TK protein kinase 0.0532 0.1487 0.3734
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Onchocerca volvulus 0.0224 0.0573 0.9047
Echinococcus multilocularis epidermal growth factor receptor 0.0268 0.0704 0.0704
Echinococcus multilocularis expressed conserved protein 0.0103 0.0213 0.0213
Schistosoma mansoni neuropeptide receptor 0.0224 0.0573 0.1367
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Echinococcus granulosus PHD finger protein rhinoceros 0.0063 0.0093 0.0233
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0001 0.0004
Brugia malayi Melatonin receptor type 1A 0.0224 0.0573 0.2552
Schistosoma mansoni chromobox protein 0.007 0.0114 0.0272
Echinococcus multilocularis tyrosine protein kinase Src42A 0.051 0.1421 0.1421
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0224 0.0573 0.1439
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0224 0.0573 0.1367
Schistosoma mansoni jumonji/arid domain-containing protein 0.0076 0.0132 0.0314
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0032 0.0001 0.0002
Echinococcus multilocularis nuclear receptor nhr 48 0.0075 0.013 0.013
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0159 0.038 0.0906
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0017 0.0214
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni neuropeptide F-like receptor 0.0224 0.0573 0.1367
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0075 0.0129 0.2033
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0125 0.0279 1
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Brugia malayi Myosin tail family protein 0.0073 0.0123 0.0549
Echinococcus granulosus Niemann Pick C1 protein 0.0157 0.0372 0.0935
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0104 0.0216 0.0541
Echinococcus granulosus peptide allatostatin:somatostatin 0.0224 0.0573 0.1439
Schistosoma mansoni histamine h1 receptor 0.0224 0.0573 0.1367
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0224 0.0573 0.2552
Onchocerca volvulus 0.0097 0.0195 0.3083
Entamoeba histolytica hypothetical protein 0.0037 0.0017 0.0135
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0159 0.038 0.0906
Loa Loa (eye worm) hypothetical protein 0.0047 0.0047 0.0117
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0059 0.0082 0.0205
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0032 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Echinococcus granulosus Nuclear hormone receptor HR96 0.0075 0.013 0.0326
Echinococcus multilocularis rhodopsin orphan GPCR 0.0224 0.0573 0.0573
Schistosoma mansoni tyrosine kinase 0.01 0.0204 0.0486
Entamoeba histolytica unconventional myosin IB 0.0073 0.0123 0.0975
Schistosoma mansoni adapter molecule crk 0.0148 0.0345 0.0824
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0159 0.038 0.1692
Echinococcus granulosus chromobox protein 1 0.007 0.0114 0.0286
Schistosoma mansoni amine GPCR 0.0224 0.0573 0.1367
Schistosoma mansoni tyrosine kinase 0.0097 0.0195 0.0466
Echinococcus multilocularis tensin 0.0075 0.0129 0.0129
Brugia malayi Tensin 0.0075 0.0129 0.0574
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.0345 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0017 0.0041
Echinococcus multilocularis chromobox protein 1 0.007 0.0114 0.0114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Schistosoma mansoni hypothetical protein 0.0224 0.0573 0.1367
Brugia malayi DOMON domain containing protein 0.0146 0.034 0.1515
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0804 1
Loa Loa (eye worm) DOMON domain-containing protein 0.0146 0.034 0.0854
Onchocerca volvulus Glucosylceramidase homolog 0.0189 0.0467 0.7378
Schistosoma mansoni adenoreceptor 0.0224 0.0573 0.1367
Entamoeba histolytica hypothetical protein 0.0073 0.0123 0.0975
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0047 0.0112
Brugia malayi CHE-14 protein 0.0047 0.0047 0.0207
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Onchocerca volvulus 0.0224 0.0573 0.9047
Echinococcus granulosus neuropeptides capa receptor 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Brugia malayi ORL1-like opioid receptor 0.0224 0.0573 0.2552
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0075 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0063 0.0093 0.0233
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Brugia malayi SH2 domain containing protein 0.0075 0.0129 0.0574
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0017 0.0043
Echinococcus multilocularis c src tyrosine kinase 0.017 0.0412 0.0412
Onchocerca volvulus 0.0075 0.0129 0.2033
Echinococcus granulosus rhodopsin orphan GPCR 0.0224 0.0573 0.1439
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0375 0.1022 0.4549
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0125 0.0279 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0224 0.0573 0.0573
Schistosoma mansoni formin binding protein and related proteins 0.0073 0.0123 0.0294
Brugia malayi putative neuropeptide receptor 0.0224 0.0573 0.2552
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0023 0.0285
Schistosoma mansoni hypothetical protein 0.0224 0.0573 0.1367
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Entamoeba histolytica hypothetical protein 0.0073 0.0123 0.0975
Echinococcus multilocularis muscleblind protein 0.0304 0.0811 0.0811
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.008 0.0146 0.0648
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0111 0.0238 0.0567
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0059 0.0082 0.0082
Onchocerca volvulus 0.0036 0.0015 0.0237
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0073 0.0123 0.031
Toxoplasma gondii ABC1 family protein 0.0037 0.0017 0.0617
Echinococcus granulosus expressed conserved protein 0.0103 0.0213 0.0534
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0224 0.0573 0.0573
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0059 0.0082 0.0205
Echinococcus granulosus glycine receptor subunit alpha 1 0.0059 0.0082 0.0205
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0762 0.2171 0.9664
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) GABA receptor subunit 0.0032 0.0001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.019 0.0453
Echinococcus multilocularis neuropeptide Y receptor 0.0224 0.0573 0.0573
Echinococcus multilocularis Spectrin alpha actinin 0.0073 0.0123 0.0123
Onchocerca volvulus 0.0097 0.0195 0.3083
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0089 0.0171 0.4969
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Trypanosoma brucei conserved protein 0.0073 0.0123 0.4416
Onchocerca volvulus 0.0059 0.0082 0.1287
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Brugia malayi SH2 domain containing protein 0.0075 0.0129 0.0574
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0075 0.0129 0.0129
Brugia malayi ecdysone receptor 0.0075 0.013 0.0579
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.0804 0.6351
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0762 0.2171 0.545
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0159 0.038 0.0954
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.0345 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0159 0.038 0.1692
Onchocerca volvulus 0.0042 0.0032 0.0509
Echinococcus multilocularis protein dispatched 1 0.0054 0.0066 0.0066
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0123 0.0549
Echinococcus multilocularis growth factor receptor bound protein 2 0.0148 0.0345 0.0345
Trypanosoma cruzi cruzipain precursor, putative 0.0042 0.0031 0.1096
Entamoeba histolytica hypothetical protein 0.0037 0.0017 0.0135
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0159 0.038 0.0954
Echinococcus multilocularis NCK adaptor protein 0.0148 0.0345 0.0345
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0159 0.038 0.0954
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0059 0.0082 0.0194
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0073 0.0123 0.031
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.0345 0.5522
Chlamydia trachomatis dihydrofolate reductase 0.0036 0.0015 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0205 0.0516 0.0516
Echinococcus granulosus neuropeptide Y receptor 0.0224 0.0573 0.1439
Brugia malayi Src substrate cortactin 0.0073 0.0123 0.0549
Echinococcus multilocularis rhodopsin orphan GPCR 0.0224 0.0573 0.0573
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0159 0.038 0.0954
Brugia malayi nuclear receptor RXR 0.0075 0.013 0.0579
Echinococcus granulosus tyrosine protein kinase HCK 0.0457 0.1265 0.3177
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0047 0.0112
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0017 0.0214
Echinococcus multilocularis G protein coupled receptor 139 0.0224 0.0573 0.0573
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0605 0.1704 0.1704
Echinococcus granulosus neuropeptide Y receptor 0.0224 0.0573 0.1439
Loa Loa (eye worm) TK/ABL protein kinase 0.1372 0.3983 1
Echinococcus multilocularis glycine receptor subunit beta 0.0059 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0304 0.0811 0.2036
Entamoeba histolytica protein kinase, putative 0.0073 0.0123 0.0975
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Loa Loa (eye worm) hypothetical protein 0.0304 0.0811 0.2036
Echinococcus granulosus tensin 0.0075 0.0129 0.0323
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.008 0.0146 0.0366
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0804 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0224 0.0573 0.0573
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0605 0.1704 0.4278
Schistosoma mansoni nAChR subunit 0.0059 0.0082 0.0194
Onchocerca volvulus 0.0224 0.0573 0.9047
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0467 0.5817
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0082 0.0363
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0097 0.0195 0.049
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0159 0.038 0.038
Loa Loa (eye worm) nuclear hormone receptor 0.0075 0.013 0.0326
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1372 0.3983 0.3983
Schistosoma mansoni tyrosine kinase 0.0154 0.0364 0.0867
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0043 0.0035 0.1251
Loa Loa (eye worm) hypothetical protein 0.0084 0.0157 0.0394
Brugia malayi Tyrosine-protein kinase abl-1 0.0787 0.2246 1
Entamoeba histolytica BAR/SH3 domain containing protein 0.0073 0.0123 0.0975
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0043
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Echinococcus granulosus SH2 domain containing adapter protein F 0.0075 0.0129 0.0323
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0159 0.038 0.0954
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0605 0.1704 0.1704
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Loa Loa (eye worm) hypothetical protein 0.011 0.0233 0.0584
Schistosoma mansoni SH2A 0.0075 0.0129 0.0307
Onchocerca volvulus 0.0037 0.0017 0.0272
Echinococcus granulosus muscleblind protein 0.0304 0.0811 0.2036
Brugia malayi Tachykinin-like peptides receptor 99D 0.0224 0.0573 0.2552
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0467 0.5817
Onchocerca volvulus 0.0075 0.0129 0.2033
Loa Loa (eye worm) TK protein kinase 0.0457 0.1265 0.3177
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0059 0.0082 0.0194
Loa Loa (eye worm) hypothetical protein 0.0084 0.0157 0.0394
Brugia malayi DOMON domain containing protein 0.0146 0.034 0.1515
Schistosoma mansoni organic anion transporter 0.0036 0.0015 0.0036
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0084 0.0157 0.0394
Schistosoma mansoni nuclear receptor nhr-48 0.0075 0.013 0.031
Schistosoma mansoni myosin xvIII 0.0224 0.0573 0.1367
Loa Loa (eye worm) serotonin transporter b 0.0075 0.013 0.0326
Echinococcus multilocularis nAChR subunit 0.0032 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0043
Onchocerca volvulus 0.005 0.0054 0.085
Loa Loa (eye worm) LGC-31 protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0159 0.038 0.0954
Trichomonas vaginalis set domain proteins, putative 0.0245 0.0634 0.7885
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0017 0.0617
Echinococcus granulosus SHC transforming protein 3 0.0075 0.0129 0.0323
Echinococcus multilocularis tyrosine protein kinase Abl 0.0657 0.186 0.186
Onchocerca volvulus 0.0075 0.013 0.2052
Echinococcus granulosus somatostatin receptor 0.0224 0.0573 0.1439
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0093 0.3318
Entamoeba histolytica hypothetical protein 0.0037 0.0017 0.0135
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0804 1
Entamoeba histolytica hypothetical protein 0.0073 0.0123 0.0975
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0017 0.0043
Echinococcus granulosus tyrosine protein kinase Fyn 0.0605 0.1704 0.4278
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Schistosoma mansoni thyroid hormone receptor 0.0159 0.038 0.0906
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0089 0.0171 0.2621
Schistosoma mansoni biogenic amine (5HT) receptor 0.0224 0.0573 0.1367
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0047 0.0118
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0224 0.0573 0.0573
Echinococcus granulosus sex peptide receptor 0.0224 0.0573 0.1439
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0082 0.0363
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0059 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Schistosoma mansoni hypothetical protein 0.0075 0.0129 0.0307
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0059 0.0082 0.0363
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Trypanosoma cruzi MFS transporter, putative 0.0036 0.0015 0.0538
Echinococcus multilocularis sex peptide receptor 0.0224 0.0573 0.0573
Brugia malayi Dopamine receptor protein 2 0.0224 0.0573 0.2552
Schistosoma mansoni sorbin 0.0073 0.0123 0.0294
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0075 0.0129 0.0129
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0075 0.0129 0.0129
Echinococcus multilocularis 0.0077 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0762 0.2171 0.545
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0123 0.1535
Echinococcus multilocularis rhodopsin orphan GPCR 0.0224 0.0573 0.0573
Onchocerca volvulus 0.0036 0.0015 0.0237
Brugia malayi sodium-independent organic anion transporter family protein 0.0036 0.0015 0.0067
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0288 0.0761 0.1911
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0017 0.0617
Echinococcus multilocularis SHC transforming protein 3 0.0075 0.0129 0.0129
Brugia malayi Furin-like cysteine rich region family protein 0.0268 0.0704 0.3133
Echinococcus multilocularis tyrosine protein kinase Srms 0.0532 0.1487 0.1487
Brugia malayi G protein-coupled receptor 0.0224 0.0573 0.2552
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0224 0.0573 0.0573
Brugia malayi protein-tyrosine kinase 0.0073 0.0123 0.0549
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0036 0.0015 0.0038
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0224 0.0573 0.1367
Echinococcus granulosus epidermal growth factor receptor 0.0268 0.0704 0.1767
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0036 0.0015 0.0015
Schistosoma mansoni opsin-like receptor 0.0224 0.0573 0.1367
Echinococcus multilocularis replication factor c subunit 1 0.0031 0.00000034603 0.00000034603
Brugia malayi PHD-finger family protein 0.0063 0.0093 0.0413
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0043 0.0035 0.1251
Schistosoma mansoni opsin-like receptor 0.0224 0.0573 0.1367
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Echinococcus multilocularis muscleblind protein 1 0.0304 0.0811 0.0811
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Echinococcus multilocularis tumor protein p63 0.0338 0.0912 0.0912
Schistosoma mansoni neuropeptide f receptor 76f 0.0224 0.0573 0.1367
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0023 0.0285
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0073 0.0123 0.1535
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0224 0.0573 0.0573
Entamoeba histolytica hypothetical protein 0.0073 0.0123 0.0975
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0159 0.038 0.0954
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0082 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0159 0.038 0.1692
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0159 0.038 0.0906
Echinococcus multilocularis SH2 motif 0.0075 0.0129 0.0129
Schistosoma mansoni GTPase activating protein 0.0075 0.0129 0.0307
Trichomonas vaginalis p67phox protein, putative 0.0073 0.0123 0.1535
Brugia malayi jmjC domain containing protein 0.0076 0.0132 0.0587
Schistosoma mansoni dihydrofolate reductase 0.0036 0.0015 0.0035
Echinococcus multilocularis thyroid hormone receptor alpha 0.0159 0.038 0.038
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0761 0.9474
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0012 0.0054
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0059 0.0082 0.0082
Onchocerca volvulus 0.0097 0.0195 0.3083
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0073 0.0123 0.0294
Onchocerca volvulus 0.0059 0.0082 0.1287
Mycobacterium tuberculosis Conserved protein 0.0037 0.0017 0.0043
Brugia malayi Bromodomain containing protein 0.0063 0.0093 0.0413
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0075 0.0129 0.0307
Loa Loa (eye worm) hypothetical protein 0.0762 0.2171 0.545
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0084 0.0157 0.0374
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0017 0.0214
Schistosoma mansoni nck2/grb4 0.0148 0.0345 0.0824
Onchocerca volvulus Putative nachr subunit 0.0059 0.0082 0.1287
Echinococcus granulosus suppressor of cytokine signaling 6 0.0075 0.0129 0.0323
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Brugia malayi Niemann-Pick C1 protein precursor 0.011 0.0233 0.1035
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0017 0.0043
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0224 0.0573 0.1439
Loa Loa (eye worm) beta-lactamase 0.0037 0.0017 0.0043
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Onchocerca volvulus 0.0097 0.0195 0.3083
Echinococcus granulosus nAChR subunit 0.0032 0.0001 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0123 0.4416
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Mycobacterium ulcerans lipase LipD 0.0037 0.0017 0.0499
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.01 0.0204 0.0204
Schistosoma mansoni tensin 0.0075 0.0129 0.0307
Loa Loa (eye worm) SRC-1 0.0605 0.1704 0.4278
Schistosoma mansoni run and tbc1 domain containing 0.0073 0.0123 0.0294
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0031 0 0.5
Brugia malayi Guanylate kinase family protein 0.0073 0.0123 0.0549
Mycobacterium tuberculosis Conserved protein 0.0037 0.0017 0.0043
Echinococcus granulosus geminin 0.014 0.0324 0.0814
Echinococcus granulosus SH2 domain containing protein 7 0.0075 0.0129 0.0323
Echinococcus granulosus ecdysone induced protein 78C 0.0159 0.038 0.0954
Echinococcus multilocularis SH2 domain containing protein 7 0.0075 0.0129 0.0129
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0159 0.038 0.0906
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0047 0.0118
Schistosoma mansoni dopamine-beta-monooxygenase 0.1443 0.4194 1
Brugia malayi hypothetical protein 0.0075 0.013 0.0579
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0467 0.5817
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.008 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0047 0.0579
Loa Loa (eye worm) jmjC domain-containing protein 0.0129 0.0291 0.073
Brugia malayi larval opioid receptor 0.0224 0.0573 0.2552
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0059 0.0082 0.0363
Echinococcus multilocularis serotonin receptor 0.0224 0.0573 0.0573
Brugia malayi prostaglandin transporter 0.0036 0.0015 0.0067
Echinococcus multilocularis protein patched 0.0047 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0075 0.013 0.031
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0059 0.0082 0.0205
Brugia malayi SRC-1 0.0605 0.1704 0.7586
Onchocerca volvulus 0.0073 0.0123 0.1946
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0224 0.0573 0.1367
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0761 0.9474
Echinococcus granulosus tm gpcr rhodopsin 0.0224 0.0573 0.1439
Echinococcus granulosus tyrosine kinase 0.0532 0.1487 0.3734
Echinococcus granulosus 7tm_1 domain containing protein 0.0224 0.0573 0.1439
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.011 0.0233 0.1838
Onchocerca volvulus 0.0059 0.0082 0.1287
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0059 0.0082 0.0082
Onchocerca volvulus 0.0224 0.0573 0.9047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0224 0.0573 0.1367
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0093 0.0222
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0467 0.5817
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0073 0.0123 0.0123
Brugia malayi neuropeptide F receptor 0.0224 0.0573 0.2552
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0082 0.0363
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0804 1
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0017 0.0214
Echinococcus granulosus tyrosine protein kinase Blk 0.0532 0.1487 0.3734
Treponema pallidum fructose-bisphosphate aldolase 0.0302 0.0804 1
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0073 0.0123 0.4416
Brugia malayi SH3 domain containing protein 0.0073 0.0123 0.0549
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Echinococcus granulosus neuropeptide receptor 0.0224 0.0573 0.1439
Schistosoma mansoni Dab2-interacting protein-like 0.0073 0.0123 0.0294
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0059 0.0082 0.0363
Schistosoma mansoni tyrosine kinase 0.0131 0.0297 0.0709
Brugia malayi SH2 domain containing protein 0.0097 0.0195 0.087
Brugia malayi Variant SH3 domain containing protein 0.0148 0.0345 0.1538
Echinococcus multilocularis tensin 0.0075 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Loa Loa (eye worm) ACC-1 protein 0.0059 0.0082 0.0205
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0059 0.0082 0.0205
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0093 0.3318
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0038 0.002 0.0712
Mycobacterium ulcerans beta-lactamase 0.0037 0.0017 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0123 0.1535
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0059 0.0082 0.0205
Echinococcus multilocularis orexin receptor type 2 0.0224 0.0573 0.0573
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0075 0.0129 0.0574
Loa Loa (eye worm) SH2 domain-containing protein 0.0075 0.0129 0.0323
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0017 0.0041
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0093 0.2699
Brugia malayi tailless protein 0.0075 0.013 0.0579
Schistosoma mansoni tyrosine kinase 0.0131 0.0297 0.0709
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0075 0.0129 0.0307
Echinococcus granulosus tyrosine protein kinase ABL1 0.1372 0.3983 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0043 0.0035 0.0083
Onchocerca volvulus 0.0059 0.0082 0.1287
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0123 0.4416
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0159 0.038 0.0954
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0762 0.2171 0.2171
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0224 0.0573 0.1439
Onchocerca volvulus 0.0245 0.0634 1
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Brugia malayi hypothetical protein 0.0036 0.0015 0.0067
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0093 0.1311
Brugia malayi hypothetical protein 0.0075 0.013 0.0579
Loa Loa (eye worm) hypothetical protein 0.0159 0.038 0.0954
Schistosoma mansoni hypothetical protein 0.0063 0.0093 0.0221
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.0157 0.0698
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0036 0.0015 0.0015
Trichomonas vaginalis chromobox protein, putative 0.007 0.0114 0.1418
Schistosoma mansoni sodium/chloride dependent transporter 0.0075 0.013 0.031
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0017 0.0077
Brugia malayi nuclear hormone receptor family member odr-7 0.0075 0.013 0.0579
Brugia malayi RhoGAP domain containing protein 0.0075 0.0129 0.0574
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0059 0.0082 0.0363
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.0804 0.6351
Schistosoma mansoni steroid hormone receptor ad4bp 0.0159 0.038 0.0906
Mycobacterium ulcerans hypothetical protein 0.0037 0.0017 0.0499
Loa Loa (eye worm) DR-78 0.0075 0.013 0.0326
Echinococcus multilocularis SH2 motif 0.0075 0.0129 0.0129
Onchocerca volvulus 0.0089 0.0171 0.2705
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0047 0.021
Loa Loa (eye worm) hypothetical protein 0.0097 0.0195 0.049
Brugia malayi Cation transporter family protein 0.0059 0.0082 0.0363
Brugia malayi thymidylate synthase 0.0089 0.0171 0.0763
Echinococcus multilocularis transfer RNA-Ala 0.0073 0.0123 0.0123
Onchocerca volvulus 0.0036 0.0015 0.0237
Echinococcus granulosus tyrosine protein kinase shark 0.0097 0.0195 0.049
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0224 0.0573 0.0573
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Brugia malayi Nuclear hormone receptor-like 1 0.0159 0.038 0.1692
Onchocerca volvulus 0.0075 0.0129 0.2033
Echinococcus granulosus N chimaerin 0.0075 0.0129 0.0323
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0032 0.0395
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0224 0.0573 0.1439
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0159 0.038 0.1692
Schistosoma mansoni tyrosine kinase 0.0605 0.1704 0.4063
Loa Loa (eye worm) jmjC domain-containing protein 0.0076 0.0132 0.0331
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0093 0.0222
Trichomonas vaginalis esterase, putative 0.0037 0.0017 0.0214
Loa Loa (eye worm) hypothetical protein 0.0052 0.0061 0.0153
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0043
Echinococcus granulosus allatostatin A receptor 0.0224 0.0573 0.1439
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0036 0.0015 0.0038
Brugia malayi tRNA modification GTPase TrmE family protein 0.0075 0.0129 0.0574
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0073 0.0123 0.031
Brugia malayi sulfakinin receptor protein 0.0224 0.0573 0.2552
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0059 0.0082 0.0205
Echinococcus granulosus biogenic amine 5HT receptor 0.0224 0.0573 0.1439
Brugia malayi Nuclear hormone receptor E75 0.0075 0.013 0.0579
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Echinococcus multilocularis g protein coupled receptor 0.0224 0.0573 0.0573
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Onchocerca volvulus 0.0224 0.0573 0.9047
Brugia malayi conserved hypotetical protein 0.0075 0.013 0.0579
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0224 0.0573 0.0573
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0089 0.0171 0.0409
Schistosoma mansoni hypothetical protein 0.0073 0.0123 0.0294
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0532 0.1487 0.3734
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0073 0.0123 0.0294
Echinococcus multilocularis nAChR subunit 0.0059 0.0082 0.0082
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0159 0.038 0.038
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Schistosoma mansoni patched 1 0.0047 0.0047 0.0111
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0224 0.0573 0.9047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0159 0.038 0.0954
Onchocerca volvulus Putative organic anion transporter 0.0036 0.0015 0.0237
Brugia malayi Protein kinase domain containing protein 0.0097 0.0195 0.087
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0159 0.038 0.038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0123 0.0549
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0224 0.0573 0.0573
Loa Loa (eye worm) nuclear receptor NHR-67 0.0075 0.013 0.0326
Onchocerca volvulus Putative organic anion transporter 0.0036 0.0015 0.0237
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni dynamin-associated protein 0.0073 0.0123 0.0294
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0082 0.0363
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0075 0.0129 0.0323
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Onchocerca volvulus Putative cortactin 0.0073 0.0123 0.1946
Brugia malayi Variant SH3 domain containing protein 0.0148 0.0345 0.1538
Entamoeba histolytica hypothetical protein 0.0032 0.0001 0.0007
Schistosoma mansoni hypothetical protein 0.0224 0.0573 0.1367
Schistosoma mansoni nAChR subunit 0.0059 0.0082 0.0194
Echinococcus granulosus glycine receptor subunit alpha 1 0.0059 0.0082 0.0205
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0532 0.1487 0.1487
Schistosoma mansoni growth factor receptor-bound protein 0.0148 0.0345 0.0824
Echinococcus multilocularis endophilin A3 0.0073 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni nAChR subunit 0.0059 0.0082 0.0194
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0017 0.0499
Loa Loa (eye worm) SH2 domain-containing protein 0.0075 0.0129 0.0323
Echinococcus granulosus g protein coupled receptor 0.0224 0.0573 0.1439
Schistosoma mansoni zinc finger protein 0.0075 0.013 0.031
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Brugia malayi SH2 domain containing protein 0.0075 0.0129 0.0574
Echinococcus granulosus intersectin 2 0.0073 0.0123 0.031
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0761 0.9474
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Schistosoma mansoni suppressor of cytokine signaling 0.0075 0.0129 0.0307
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0047 0.0112
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0059 0.0082 0.0205
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0075 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0058 0.0078 0.0196
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0043
Loa Loa (eye worm) hypothetical protein 0.0073 0.0123 0.031
Echinococcus granulosus insulin receptor 0.01 0.0204 0.0512
Echinococcus multilocularis 0.0075 0.0129 0.0129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Echinococcus multilocularis neuropeptides capa receptor 0.0224 0.0573 0.0573
Brugia malayi hypothetical protein 0.0037 0.0017 0.0076
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.008 0.0146 0.0347
Echinococcus granulosus glycine receptor subunit beta 0.0059 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0159 0.038 0.0954
Onchocerca volvulus 0.0224 0.0573 0.9047
Onchocerca volvulus Bile acid receptor homolog 0.0159 0.038 0.5998
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Schistosoma mansoni retinoic acid receptor RXR 0.0159 0.038 0.0906
Schistosoma mansoni amine GPCR 0.0224 0.0573 0.1367
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0059 0.0082 0.0363
Echinococcus granulosus rhodopsin orphan GPCR 0.0224 0.0573 0.1439
Echinococcus granulosus growth factor receptor bound protein 2 0.0148 0.0345 0.0867
Schistosoma mansoni tensin-related 0.0075 0.0129 0.0307
Loa Loa (eye worm) G-protein coupled receptor 0.0224 0.0573 0.1439
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0387 0.1056 0.47
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0159 0.038 0.0906
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0017 0.0043
Echinococcus granulosus serotonin transporter 0.0075 0.013 0.0326
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0075 0.0129 0.0323
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0605 0.1704 0.1704
Brugia malayi Serotonin receptor 0.0224 0.0573 0.2552
Schistosoma mansoni hypothetical protein 0.014 0.0324 0.0773
Echinococcus multilocularis rhodopsin orphan GPCR 0.0224 0.0573 0.0573
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0224 0.0573 0.0573
Entamoeba histolytica hypothetical protein, conserved 0.0073 0.0123 0.0975
Loa Loa (eye worm) melatonin receptor type 1A 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0033 0.0406
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0159 0.038 0.0906
Brugia malayi hypothetical protein 0.0042 0.0033 0.0145
Echinococcus multilocularis tyrosine protein kinase HCK 0.0457 0.1265 0.1265
Loa Loa (eye worm) hypothetical protein 0.0036 0.0012 0.0031
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0073 0.0123 0.0123
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0043 0.0035 0.1251
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.0157 0.0698
Brugia malayi Steroid receptor seven-up type 2 0.0159 0.038 0.1692
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0159 0.038 0.1692
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0467 0.5817
Echinococcus multilocularis dihydrofolate reductase 0.0036 0.0015 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0159 0.038 0.0906
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0075 0.0129 0.0307
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0017 0.0043
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0063 0.0093 0.0221
Brugia malayi Serotonin receptor 0.0224 0.0573 0.2552
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0075 0.0129 0.0129
Onchocerca volvulus 0.0224 0.0573 0.9047
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0093 0.2894
Leishmania major cathepsin L-like protease 0.0042 0.0031 0.0512
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0073 0.0123 0.031
Schistosoma mansoni dreadlocks/dock 0.0073 0.0123 0.0294
Loa Loa (eye worm) STAT protein 0.0075 0.0129 0.0323
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0059 0.0082 0.0363
Brugia malayi hypothetical protein 0.0075 0.0129 0.0574
Schistosoma mansoni neuropeptide receptor 0.0224 0.0573 0.1367
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0159 0.038 0.5998
Loa Loa (eye worm) hypothetical protein 0.0036 0.0015 0.0038
Loa Loa (eye worm) DOMON domain-containing protein 0.0146 0.034 0.0854
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0075 0.0129 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0093 0.0234
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0605 0.1704 0.1704
Loa Loa (eye worm) hypothetical protein 0.008 0.0146 0.0366
Onchocerca volvulus 0.0224 0.0573 0.9047
Schistosoma mansoni hypothetical protein 0.008 0.0146 0.0347
Schistosoma mansoni coup transcription factor 0.0159 0.038 0.0906
Brugia malayi GnHR receptor homolog 0.0224 0.0573 0.2552
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.0031 0.1096
Echinococcus granulosus fmrfamide receptor 0.0224 0.0573 0.1439
Echinococcus granulosus dihydrofolate reductase 0.0036 0.0015 0.0037
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0059 0.0082 0.0363
Echinococcus granulosus rhodopsin orphan GPCR 0.0224 0.0573 0.1439
Schistosoma mansoni nAChR subunit 0.0059 0.0082 0.0194
Schistosoma mansoni nAChR subunit 0.0059 0.0082 0.0194
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0032 0.05
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0047 0.0117
Onchocerca volvulus Neuropeptide F receptor homolog 0.0224 0.0573 0.9047
Loa Loa (eye worm) hypothetical protein 0.0036 0.0015 0.0038
Brugia malayi sodium-independent organic anion transporter family protein 0.0036 0.0015 0.0067
Brugia malayi nuclear receptor NHR-67 0.0075 0.013 0.0579
Brugia malayi Protein kinase domain containing protein 0.0097 0.0195 0.087
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0123 0.1535
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0123 0.0549
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Onchocerca volvulus 0.0073 0.0123 0.1946
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0224 0.0573 0.0573
Onchocerca volvulus 0.0073 0.0123 0.1946
Schistosoma mansoni tensin 0.0075 0.0129 0.0307
Echinococcus granulosus tachykinin peptides receptor 99D 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Entamoeba histolytica BAR/SH3 domain containing protein 0.0073 0.0123 0.0975
Schistosoma mansoni signal transduction protein lnk-related 0.0075 0.0129 0.0307
Onchocerca volvulus 0.0097 0.0195 0.3083
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0059 0.0082 0.0194
Loa Loa (eye worm) hypothetical protein 0.005 0.0054 0.0135
Echinococcus multilocularis g protein coupled receptor 0.0224 0.0573 0.0573
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0017 0.0043
Brugia malayi Cation transporter family protein 0.0059 0.0082 0.0363
Schistosoma mansoni RAR-like nuclear receptor 0.0159 0.038 0.0906
Echinococcus granulosus g protein coupled receptor 0.0224 0.0573 0.1439
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0097 0.0195 0.0195
Schistosoma mansoni opsin-like receptor 0.0224 0.0573 0.1367
Brugia malayi excitatory GABA receptor EXP-1A 0.0059 0.0082 0.0363
Entamoeba histolytica hypothetical protein 0.0037 0.0017 0.0135
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0224 0.0573 0.1439
Echinococcus multilocularis jumonji domain containing protein 0.0087 0.0165 0.0165
Brugia malayi Nuclear hormone receptor E75 0.0075 0.013 0.0579
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0075 0.013 0.0579
Schistosoma mansoni chromobox protein 0.007 0.0114 0.0272
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Echinococcus multilocularis insulin receptor 0.01 0.0204 0.0204
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0047 0.0117
Brugia malayi SH2 domain containing protein 0.0075 0.0129 0.0574
Echinococcus granulosus orexin receptor type 2 0.0224 0.0573 0.1439
Loa Loa (eye worm) solute carrier family 6 member 4 0.0075 0.013 0.0326
Schistosoma mansoni tensin-related 0.0075 0.0129 0.0307
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0043 0.0035 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0123 0.4416
Schistosoma mansoni shc transforming protein 0.0075 0.0129 0.0307
Leishmania major cathepsin L-like protease 0.0042 0.0031 0.0512
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0075 0.013 0.031
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0159 0.038 0.1692
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Echinococcus granulosus lysine specific demethylase 5A 0.0076 0.0132 0.0331
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0059 0.0082 0.0205
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0073 0.0123 0.0123
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0224 0.0573 0.1439
Echinococcus granulosus 7TM GPCR rhodopsin 0.0224 0.0573 0.1439
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0159 0.038 0.0954
Echinococcus granulosus tyrosine protein kinase Fyn 0.0605 0.1704 0.4278
Schistosoma mansoni jumonji domain containing protein 0.0163 0.0391 0.0931
Onchocerca volvulus 0.0097 0.0195 0.3083
Echinococcus granulosus epidermal growth factor receptor kinase 0.0073 0.0123 0.031
Onchocerca volvulus 0.0075 0.0129 0.2033
Echinococcus granulosus FTZ F1 alpha 0.0159 0.038 0.0954
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0125 0.0279 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Schistosoma mansoni hypothetical protein 0.014 0.0324 0.0773
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.0093 0.0233
Echinococcus multilocularis nostrin 0.0073 0.0123 0.0123
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0059 0.0082 0.0363
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0043 0.0035 0.0088
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0017 0.0499
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Echinococcus granulosus tyrosine protein kinase Src42A 0.0605 0.1704 0.4278
Echinococcus granulosus neuropeptide receptor 0.0224 0.0573 0.1439
Echinococcus multilocularis FTZ F1 alpha 0.0159 0.038 0.038
Brugia malayi nuclear hormone receptor 0.0075 0.013 0.0579
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0075 0.0129 0.0323
Brugia malayi beta-lactamase family protein 0.0037 0.0017 0.0077
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0032 0.0077
Treponema pallidum sodium- and chloride- dependent transporter 0.0075 0.013 0.1618
Brugia malayi Muscleblind-like protein 0.0304 0.0811 0.3609
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0073 0.0123 0.1946
Echinococcus granulosus replication factor c subunit 1 0.0031 0.00000034603 0.00000086874
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0224 0.0573 0.1367
Brugia malayi cytokine inducible SH2-containing protein 5 0.0075 0.0129 0.0574
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0061 0.0153
Schistosoma mansoni growth hormone secretagogue receptor 0.0224 0.0573 0.1367
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) norepinephrine transporter 0.0075 0.013 0.0326
Echinococcus multilocularis ecdysone induced protein 78C 0.0159 0.038 0.038
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Echinococcus granulosus Nuclear hormone receptor HR96 0.0075 0.013 0.0326
Echinococcus multilocularis SH2 motif 0.0075 0.0129 0.0129
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0047 0.0047
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0804 1
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0031 0.00000034603 0.0000027348
Echinococcus granulosus tm gpcr rhodopsin 0.0224 0.0573 0.1439
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0224 0.0573 0.1439
Brugia malayi SH2 domain containing protein 0.0075 0.0129 0.0574
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Entamoeba histolytica SH2 domain containing protein 0.0075 0.0129 0.1018
Echinococcus multilocularis intersectin 2 0.0073 0.0123 0.0123
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0075 0.0129 0.0323
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0054 0.0128
Brugia malayi Pre-SET motif family protein 0.0215 0.0545 0.2428
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0075 0.013 0.0326
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Brugia malayi G-protein coupled receptor 0.0224 0.0573 0.2552
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0159 0.038 0.0954
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Echinococcus multilocularis serotonin receptor 0.0224 0.0573 0.0573
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0224 0.0573 0.1367
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0075 0.013 0.0579
Schistosoma mansoni neuropeptide F-like receptor 0.0224 0.0573 0.1367
Echinococcus granulosus Niemann Pick C1 protein 0.011 0.0233 0.0584
Loa Loa (eye worm) TK/INSR protein kinase 0.01 0.0204 0.0512
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.0031 0.1096
Echinococcus multilocularis N chimaerin 0.0075 0.0129 0.0129
Brugia malayi Dihydrofolate reductase 0.0036 0.0015 0.0065
Schistosoma mansoni C-fyn 0.0073 0.0123 0.0294
Onchocerca volvulus 0.0224 0.0573 0.9047
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0114 0.0286
Echinococcus granulosus dro:myosuppressin receptor 0.0224 0.0573 0.1439
Brugia malayi sodium-independent organic anion transporter family protein 0.0036 0.0015 0.0067
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0224 0.0573 0.2552
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0075 0.0129 0.0323
Schistosoma mansoni organic anion transporter 0.0036 0.0015 0.0036
Onchocerca volvulus 0.0224 0.0573 0.9047
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0148 0.0345 0.0824
Brugia malayi G-protein coupled receptor 0.0224 0.0573 0.2552
Loa Loa (eye worm) thymidylate synthase 0.0089 0.0171 0.043
Brugia malayi Protein kinase domain containing protein 0.01 0.0204 0.0907
Onchocerca volvulus 0.0146 0.034 0.537
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0059 0.0082 0.0082
Brugia malayi hypothetical protein 0.0084 0.0157 0.0698
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0073 0.0123 0.0123
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.0613 1
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Echinococcus granulosus glycine receptor subunit alpha 1 0.0059 0.0082 0.0205
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0605 0.1704 0.1704
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0032 0.0395
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0075 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Brugia malayi Variant SH3 domain containing protein 0.0075 0.0129 0.0574
Echinococcus multilocularis dro:myosuppressin receptor 0.0224 0.0573 0.0573
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0159 0.038 0.1692
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0467 0.5817
Loa Loa (eye worm) hypothetical protein 0.0107 0.0226 0.0566
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Echinococcus granulosus tyrosine protein kinase Fyn 0.0605 0.1704 0.4278
Echinococcus granulosus epidermal growth factor receptor 0.0154 0.0364 0.0913
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0043 0.0035 0.0088
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0093 0.0093
Brugia malayi nuclear hormone receptor family member nhr-6 0.0075 0.013 0.0579
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0073 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.008 0.0146 0.0347
Brugia malayi Fes/CIP4 homology domain containing protein 0.0073 0.0123 0.0549
Loa Loa (eye worm) hypothetical protein 0.0036 0.0015 0.0038
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0001 0.0004
Leishmania major cathepsin L-like protease 0.0042 0.0031 0.0512
Echinococcus multilocularis G-protein coupled receptor, putative 0.0224 0.0573 0.0573
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Loa Loa (eye worm) hypothetical protein 0.0036 0.0015 0.0038
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Onchocerca volvulus 0.0036 0.0015 0.0237
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0036 0.0015 0.0425
Echinococcus granulosus G protein coupled receptor 139 0.0224 0.0573 0.1439
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0017 0.0043
Loa Loa (eye worm) protein-tyrosine kinase 0.0073 0.0123 0.031
Onchocerca volvulus 0.0059 0.0082 0.1287
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0059 0.0082 0.0205
Echinococcus multilocularis geminin 0.014 0.0324 0.0324
Echinococcus multilocularis chromobox protein 1 0.007 0.0114 0.0114
Echinococcus granulosus suppressor of cytokine signaling 7 0.0075 0.0129 0.0323
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0159 0.038 0.038
Onchocerca volvulus 0.0075 0.013 0.2052
Brugia malayi SH2 domain containing protein 0.0075 0.0129 0.0574
Loa Loa (eye worm) hypothetical protein 0.0159 0.038 0.0954
Onchocerca volvulus 0.0224 0.0573 0.9047
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0075 0.013 0.013
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0075 0.0129 0.2033
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.017 0.0412 0.0412
Loa Loa (eye worm) neuropeptide F receptor 0.0224 0.0573 0.1439
Schistosoma mansoni hypothetical protein 0.0045 0.0042 0.0099
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0605 0.1704 0.1704
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0159 0.038 0.038
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0023 0.0361
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0075 0.013 0.2052
Brugia malayi SH2 domain containing protein 0.0075 0.0129 0.0574
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Entamoeba histolytica hypothetical protein 0.0073 0.0123 0.0975
Schistosoma mansoni sorting nexin 0.0073 0.0123 0.0294
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0032 0.0001 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0017 0.0214
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0125 0.0279 1
Onchocerca volvulus 0.0224 0.0573 0.9047
Echinococcus granulosus neuropeptide FF receptor 2 0.0224 0.0573 0.1439
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0159 0.038 0.1692
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0148 0.0345 0.0867
Loa Loa (eye worm) dihydrofolate reductase 0.0036 0.0015 0.0037
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Brugia malayi Peripheral plasma membrane protein CASK 0.0073 0.0123 0.0549
Echinococcus granulosus Solute carrier organic anion transporter family 0.0036 0.0015 0.0038
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Brugia malayi Angiotensin-converting enzyme family protein 0.0104 0.0216 0.096
Brugia malayi hypothetical protein 0.0097 0.0195 0.087
Echinococcus multilocularis tyrosine kinase 0.0097 0.0195 0.0195
Brugia malayi STAT protein, DNA binding domain containing protein 0.0075 0.0129 0.0574
Echinococcus multilocularis allatostatin A receptor 0.0224 0.0573 0.0573
Echinococcus multilocularis fmrfamide receptor 0.0224 0.0573 0.0573
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0093 0.2699
Schistosoma mansoni biogenic amine receptor 0.0224 0.0573 0.1367
Brugia malayi orphan nuclear receptor NR2E1 0.0075 0.013 0.0579
Schistosoma mansoni tensin 0.0075 0.0129 0.0307
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Schistosoma mansoni tyrosine kinase 0.01 0.0204 0.0486
Echinococcus granulosus g protein coupled receptor 0.0224 0.0573 0.1439
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0075 0.013 0.013
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0059 0.0082 0.0082
Echinococcus multilocularis glycine receptor subunit beta 0.0059 0.0082 0.0082
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0061 0.0272
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0059 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Schistosoma mansoni amine GPCR 0.0224 0.0573 0.1367
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0224 0.0573 0.0573
Schistosoma mansoni suppressor of cytokine signaling 0.0075 0.0129 0.0307
Schistosoma mansoni biogenic amine (5HT) receptor 0.0224 0.0573 0.1367
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0761 0.9474
Loa Loa (eye worm) SH2 domain-containing protein 0.0075 0.0129 0.0323
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0043 0.0035 0.0676
Brugia malayi follicle stimulating hormone receptor 0.0224 0.0573 0.2552
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Brugia malayi Variant SH3 domain containing protein 0.0075 0.0129 0.0574
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0047 0.0047
Onchocerca volvulus 0.0224 0.0573 0.9047
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Brugia malayi jmjC domain containing protein 0.0205 0.0516 0.2296
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0288 0.0761 0.3389
Leishmania major hypothetical protein, conserved 0.0073 0.0123 0.4049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0804 1
Echinococcus granulosus chromobox protein 1 0.007 0.0114 0.0286
Entamoeba histolytica hypothetical protein, conserved 0.0073 0.0123 0.0975
Echinococcus granulosus tyrosine protein kinase Src64B 0.0605 0.1704 0.4278
Schistosoma mansoni hypothetical protein 0.0036 0.0012 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0042 0.0031 0.1096
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0075 0.0129 0.0129
Echinococcus granulosus tm gpcr rhodopsin 0.0224 0.0573 0.1439
Brugia malayi hypothetical protein 0.0036 0.0015 0.0067
Schistosoma mansoni tyrosine kinase 0.017 0.0412 0.0982
Onchocerca volvulus Alhambra homolog 0.0063 0.0093 0.1463
Brugia malayi Dopamine receptor protein 1 0.0224 0.0573 0.2552
Loa Loa (eye worm) G-protein coupled receptor 0.0224 0.0573 0.1439
Echinococcus multilocularis g protein coupled receptor 0.0224 0.0573 0.0573
Echinococcus granulosus thyroid hormone receptor alpha 0.0075 0.013 0.0326
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.00000034603 0.0000043061
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0159 0.038 0.038
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0154 0.0364 0.0913
Loa Loa (eye worm) hypothetical protein 0.0084 0.0157 0.0394
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0047 0.0117
Schistosoma mansoni hypothetical protein 0.0045 0.0042 0.0099
Schistosoma mansoni hypothetical protein 0.0045 0.0042 0.0099
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0224 0.0573 0.1367
Brugia malayi Protein kinase domain containing protein 0.0097 0.0195 0.087
Schistosoma mansoni tyrosine kinase 0.017 0.0412 0.0982
Echinococcus granulosus hypothetical protein 0.0075 0.0129 0.0323
Loa Loa (eye worm) TK/FER protein kinase 0.0097 0.0195 0.049
Brugia malayi SH2 domain containing protein 0.0097 0.0195 0.087
Schistosoma mansoni amine GPCR 0.0224 0.0573 0.1367
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0159 0.038 0.1692
Onchocerca volvulus 0.0159 0.038 0.5998
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0017 0.0043
Schistosoma mansoni tyrosine kinase 0.1297 0.3761 0.8969
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Onchocerca volvulus 0.0073 0.0123 0.1946
Brugia malayi DOMON domain containing protein 0.0146 0.034 0.1515
Brugia malayi Protein kinase domain containing protein 0.0097 0.0195 0.087
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0075 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0043
Loa Loa (eye worm) guanylate kinase 0.0073 0.0123 0.031
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0073 0.0123 0.031
Echinococcus granulosus tyrosine kinase 0.0097 0.0195 0.049
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0075 0.013 0.0326
Echinococcus granulosus peregrin 0.0063 0.0093 0.0233
Echinococcus granulosus insulin growth factor 1 receptor beta 0.01 0.0204 0.0512
Schistosoma mansoni amine GPCR 0.0224 0.0573 0.1367
Echinococcus granulosus rhodopsin orphan GPCR 0.0224 0.0573 0.1439
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0073 0.0123 0.0123
Entamoeba histolytica hypothetical protein 0.0073 0.0123 0.0975
Brugia malayi Cation transporter family protein 0.0059 0.0082 0.0363
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0047 0.0047
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0059 0.0082 0.0194
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0762 0.2171 0.9664
Schistosoma mansoni cell polarity protein 0.0073 0.0123 0.0294
Echinococcus granulosus neuropeptide receptor A26 0.0224 0.0573 0.1439
Onchocerca volvulus 0.0059 0.0082 0.1287
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0075 0.013 0.031
Echinococcus multilocularis neuropeptides capa receptor 0.0224 0.0573 0.0573
Trichomonas vaginalis glucosylceramidase, putative 0.0288 0.0761 0.9474
Echinococcus granulosus neuropeptide s receptor 0.0224 0.0573 0.1439
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0059 0.0082 0.0082
Brugia malayi nuclear receptor RXR 0.0084 0.0157 0.0698
Echinococcus multilocularis thymidylate synthase 0.0089 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.051 0.1422 0.3569
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0093 0.2699
Loa Loa (eye worm) p53BP2 0.0073 0.0123 0.031
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0605 0.1704 0.4278
Trichomonas vaginalis chromobox protein, putative 0.007 0.0114 0.1418
Schistosoma mansoni eps8-related protein 0.0073 0.0123 0.0294
Brugia malayi dihydrofolate reductase family protein 0.0036 0.0015 0.0065
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0224 0.0573 0.1439
Schistosoma mansoni hypothetical protein 0.0073 0.0123 0.0294
Brugia malayi nuclear receptor NHR-88 0.0159 0.038 0.1692
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0224 0.0573 0.1367
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0059 0.0082 0.0082
Brugia malayi photoreceptor-specific nuclear receptor 0.0159 0.038 0.1692
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0075 0.0129 0.0129
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0224 0.0573 0.2552
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0762 0.2171 0.5177
Loa Loa (eye worm) thyroid receptor interactor 0.0073 0.0123 0.031
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0017 0.0617
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0043 0.0035 0.0035
Loa Loa (eye worm) TK/EGFR protein kinase 0.0268 0.0704 0.1767
Brugia malayi Sex muscle abnormal protein 5 0.0148 0.0345 0.1538
Trypanosoma cruzi cysteine peptidase, putative 0.0042 0.0031 0.1096
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.008 0.0146 0.0366
Echinococcus multilocularis expressed protein 0.0073 0.0123 0.0123
Echinococcus multilocularis somatostatin receptor 0.0224 0.0573 0.0573
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0224 0.0573 0.0573
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0123 0.0549
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0042 0.0033 0.1168
Brugia malayi AKH receptor 0.0224 0.0573 0.2552
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0084 0.0157 0.0394
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0075 0.0129 0.1018
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0224 0.0573 0.2552
Brugia malayi protein-tyrosine kinase 0.0532 0.1487 0.6622
Loa Loa (eye worm) hypothetical protein 0.0032 0.0001 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0159 0.038 0.1692
Loa Loa (eye worm) hypothetical protein 0.0148 0.0345 0.0867
Schistosoma mansoni neuropeptide receptor 0.0224 0.0573 0.1367
Onchocerca volvulus 0.0032 0.0001 0.0014
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0224 0.0573 0.1367
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0097 0.0195 0.1544
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0017 0.0017
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0073 0.0123 0.0294
Toxoplasma gondii transporter, major facilitator family protein 0.0036 0.0015 0.0538
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0205
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0075 0.0129 0.0323
Echinococcus multilocularis neuropeptide s receptor 0.0224 0.0573 0.0573
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0224 0.0573 0.1367
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0017 0.0017
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0224 0.0573 0.2552
Schistosoma mansoni tyrosine kinase 0.0605 0.1704 0.4063
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Brugia malayi Tyrosine-protein kinase abl-1 0.0657 0.186 0.8281
Loa Loa (eye worm) hypothetical protein 0.0075 0.0129 0.0323
Echinococcus granulosus tyrosine protein kinase Src42A 0.051 0.1421 0.3567
Mycobacterium leprae Probable lipase LipE 0.0037 0.0017 0.0499
Echinococcus granulosus jumonji domain containing protein 0.0087 0.0165 0.0415
Brugia malayi RE15519p 0.0224 0.0573 0.2552
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0224 0.0573 0.0573
Mycobacterium tuberculosis Conserved protein 0.0037 0.0017 0.0043
Onchocerca volvulus 0.0224 0.0573 0.9047
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.017 0.0412 0.0982
Schistosoma mansoni chromosome transmission fidelity factor 0.0031 0.00000034603 0.00000082513
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.00000034603 0.0000043061
Loa Loa (eye worm) hypothetical protein 0.0224 0.0573 0.1439
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0804 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0159 0.038 0.0954
Echinococcus granulosus tyrosine protein kinase Btk29A 0.017 0.0412 0.1034
Entamoeba histolytica protein kinase, putative 0.0457 0.1265 1
Echinococcus granulosus endophilin A3 0.0073 0.0123 0.031
Echinococcus granulosus expressed conserved protein 0.0075 0.0129 0.0323
Echinococcus granulosus SH2 motif 0.0075 0.0129 0.0323
Loa Loa (eye worm) hypothetical protein 0.0159 0.038 0.0954
Echinococcus multilocularis neuropeptide receptor 0.0224 0.0573 0.0573
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0075 0.013 0.0326
Echinococcus granulosus neuropeptides capa receptor 0.0224 0.0573 0.1439
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.0498 0.6193
Echinococcus granulosus rhodopsin orphan GPCR 0.0224 0.0573 0.1439
Brugia malayi Spectrin alpha chain 0.0073 0.0123 0.0549
Brugia malayi hypothetical protein 0.0224 0.0573 0.2552
Brugia malayi putative neuropeptide receptor NPR1 0.0224 0.0573 0.2552
Schistosoma mansoni hypothetical protein 0.0045 0.0042 0.0099
Echinococcus granulosus hypothetical protein 0.0224 0.0573 0.1439
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0125 0.0279 1
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0125 0.0279 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0605 0.1704 0.1704
Echinococcus multilocularis neuropeptide receptor A26 0.0224 0.0573 0.0573
Echinococcus multilocularis tyrosine protein kinase Blk 0.0532 0.1487 0.1487
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0159 0.038 0.1692
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0059 0.0082 0.0205
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Brugia malayi ecdysteroid receptor 0.0159 0.038 0.1692
Onchocerca volvulus Putative organic anion transporter 0.0036 0.0015 0.0237
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0073 0.0123 0.0294
Echinococcus multilocularis PHD finger protein rhinoceros 0.0063 0.0093 0.0093
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0073 0.0123 0.031
Echinococcus granulosus tyrosine protein kinase Srms 0.0097 0.0195 0.049
Brugia malayi Protein kinase domain containing protein 0.0097 0.0195 0.087
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0075 0.0129 0.0323
Mycobacterium ulcerans thymidylate synthase 0.0089 0.0171 0.4969
Brugia malayi Heterochromatin protein 1 0.007 0.0114 0.0507
Schistosoma mansoni nAChR subunit 0.0059 0.0082 0.0194
Echinococcus granulosus biogenic amine 5HT receptor 0.0224 0.0573 0.1439
Loa Loa (eye worm) apoptosis regulator protein 0.008 0.0146 0.0366
Echinococcus granulosus alpha 1A adrenergic receptor 0.0224 0.0573 0.1439
Echinococcus granulosus expressed protein 0.0073 0.0123 0.031
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0093 0.3332
Brugia malayi nuclear hormone receptor 0.0159 0.038 0.1692
Schistosoma mansoni apoptosis regulator bax 0.008 0.0146 0.0347
Plasmodium falciparum phd finger protein, putative 0.0063 0.0093 0.3318
Mycobacterium tuberculosis Hypothetical protein 0.0042 0.0033 0.0301
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0073 0.0123 0.031
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.0498 0.6193
Onchocerca volvulus 0.0224 0.0573 0.9047
Loa Loa (eye worm) neuropeptide F receptor 0.0224 0.0573 0.1439
Loa Loa (eye worm) hypothetical protein 0.0075 0.013 0.0326
Onchocerca volvulus 0.0037 0.0017 0.0272

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1492 nM Binding affinity against human vasopressin V1a receptor expressed in CHO cells ChEMBL. 15857144
Ki (binding) = 1492 nM Binding affinity against human vasopressin V1a receptor expressed in CHO cells ChEMBL. 15857144

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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