Detailed information for compound 430942

Basic information

Technical information
  • TDR Targets ID: 430942
  • Name: (2S)-2-acetamido-3-[4-[2-[4-(4-chlorobenzoyl) phenoxy]ethoxy]phenyl]propanoic acid
  • MW: 481.925 | Formula: C26H24ClNO6
  • H donors: 2 H acceptors: 4 LogP: 4.73 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)N[C@H](C(=O)O)Cc1ccc(cc1)OCCOc1ccc(cc1)C(=O)c1ccc(cc1)Cl
  • InChi: 1S/C26H24ClNO6/c1-17(29)28-24(26(31)32)16-18-2-10-22(11-3-18)33-14-15-34-23-12-6-20(7-13-23)25(30)19-4-8-21(27)9-5-19/h2-13,24H,14-16H2,1H3,(H,28,29)(H,31,32)/t24-/m0/s1
  • InChiKey: YUKMJPLTJFSCAN-DEOSSOPVSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-acetamido-3-[4-[2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]ethoxy]phenyl]propanoic acid
  • (2S)-2-acetamido-3-[4-[2-[4-(4-chlorophenyl)carbonylphenoxy]ethoxy]phenyl]propanoic acid
  • (2S)-2-acetamido-3-[4-[2-[4-(4-chlorobenzoyl)phenoxy]ethoxy]phenyl]propionic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni nuclear hormone receptor 0.003 0.01 0.0349
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0201 0.1184 1
Brugia malayi Pax transcription activation domain interacting protein 0.005 0.0228 0.0798
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0048 0.0211 0.0737
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0226 0.1757
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0061 0.0293 0.1024
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0089 0.0311
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0127 0.0127
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.005 0.0228 0.4092
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0017 0.0016 0.0054
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0089 0.2618
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0075 0.0263
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0521 0.1751
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.01 0.0349
Leishmania major glycerol uptake protein, putative 0.0025 0.0066 0.0819
Echinococcus multilocularis Niemann Pick C1 protein 0.0198 0.1165 0.1165
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.004 0.0296
Echinococcus granulosus carboxylesterase 5A 0.0282 0.1701 0.5948
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0698 0.2442
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.004 0.0127
Brugia malayi TAR-binding protein 0.0125 0.0698 0.2442
Entamoeba histolytica glycogenphosphorylase, putative 0.0201 0.1184 0.4108
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.004 0.0139
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0282 0.1701 0.5948
Loa Loa (eye worm) hypothetical protein 0.0071 0.0358 0.1251
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.005 0.0228 0.0748
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0075 0.0263
Trypanosoma cruzi FHA domain containing protein, putative 0.005 0.0228 0.4092
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0269 0.094
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0047 0.0165
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0269 0.0859
Schistosoma mansoni hypothetical protein 0.008 0.0418 0.1461
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0698 0.2442
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0025 0.0066 0.1858
Onchocerca volvulus Bile acid receptor homolog 0.003 0.01 0.0349
Brugia malayi MH2 domain containing protein 0.0117 0.065 0.2273
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0108 0.0377
Echinococcus granulosus Niemann Pick C1 protein 0.0283 0.1704 0.5961
Echinococcus granulosus glycogen phosphorylase 0.0465 0.286 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.01 0.0349
Echinococcus multilocularis protein dispatched 1 0.0097 0.0523 0.0523
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0158
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0521 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0047 0.0047
Onchocerca volvulus Putative nachr subunit 0.0032 0.0108 0.0377
Loa Loa (eye worm) mbt repeat family protein 0.0061 0.0293 0.1024
Onchocerca volvulus 0.0021 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0228 0.4092
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.004 0.0158
Schistosoma mansoni ran 0.0022 0.0047 0.0165
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0108 0.0377
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0379 0.1327
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0089 0.0311
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0269 0.4907
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0025 0.0066 0.0177
Leishmania major glycerol uptake protein, putative 0.0025 0.0066 0.0819
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0228 0.0716
Schistosoma mansoni neuroligin 3 (S09 family) 0.0048 0.0211 0.0737
Schistosoma mansoni glycogen phosphorylase 0.0465 0.286 1
Plasmodium vivax importin-beta 2, putative 0.003 0.0097 0.329
Onchocerca volvulus Glycogen phosphorylase homolog 0.0465 0.286 1
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0269 0.0859
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0025 0.0066 0.0066
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.005 0.0228 0.1753
Schistosoma mansoni hypothetical protein 0.0094 0.0506 0.1771
Brugia malayi AMP-binding enzyme family protein 0.0021 0.004 0.0139
Schistosoma mansoni acetylcholinesterase 0.0048 0.0211 0.0737
Brugia malayi RNA, U transporter 1 0.0085 0.0447 0.1562
Loa Loa (eye worm) hypothetical protein 0.0053 0.0244 0.0853
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.01 0.0349
Leishmania major importin beta-1 subunit, putative 0.0024 0.0061 0.0729
Brugia malayi steroid hormone receptor 0.003 0.01 0.0349
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0521 0.1823
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0047 0.0165
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.004 0.067
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0025 0.0066 0.0066
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0158
Entamoeba histolytica vacuolar protein sorting 26 0.0025 0.0066 0.0177
Loa Loa (eye worm) hypothetical protein 0.0462 0.2843 0.9944
Leishmania major glycerol uptake protein, putative 0.0025 0.0066 0.0819
Schistosoma mansoni patched 1 0.0085 0.0447 0.1564
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0269 0.0859
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0215 0.0752
Loa Loa (eye worm) hypothetical protein 0.003 0.0097 0.034
Echinococcus granulosus tumor protein p63 0.0331 0.2009 0.7024
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0226 0.1757
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0358 0.2893
Giardia lamblia Replication factor C, subunit 1 0.005 0.0228 0.0717
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0104 0.0363
Echinococcus granulosus survival motor neuron protein 1 0.0462 0.2843 0.9944
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0349
Brugia malayi Latrophilin receptor protein 2 0.008 0.0418 0.1461
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Onchocerca volvulus 0.0103 0.0562 0.1967
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0358 0.6703
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0269 0.4907
Loa Loa (eye worm) hypothetical protein 0.005 0.0228 0.0798
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.01 0.0349
Echinococcus granulosus polycomb protein SCMH1 0.0061 0.0293 0.1024
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0032 0.0108 0.0377
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0032 0.0108 0.0377
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.005 0.0228 0.5925
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0103 0.0562 0.1967
Schistosoma mansoni chromosome transmission fidelity factor 0.005 0.0228 0.0798
Schistosoma mansoni topbp1 0.005 0.0228 0.0798
Brugia malayi Cation transporter family protein 0.0103 0.0562 0.1967
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0139
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.01 0.0349
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.004 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.01 0.0349
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0447 0.1564
Echinococcus granulosus peregrin 0.0029 0.0089 0.0311
Trypanosoma cruzi hypothetical protein, conserved 0.005 0.0228 0.4092
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.01 0.0349
Brugia malayi Carboxylesterase family protein 0.0282 0.1701 0.5948
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.01 0.0349
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0054
Echinococcus granulosus lamin dm0 0.0026 0.0075 0.0263
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0269 0.4907
Brugia malayi Carboxylesterase family protein 0.0048 0.0211 0.0737
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0061 0.0729
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Entamoeba histolytica glycogen phosphorylase, putative 0.0201 0.1184 0.4108
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0501 0.0501
Trypanosoma brucei glycerol uptake protein, putative 0.0025 0.0066 0.0819
Mycobacterium tuberculosis Carboxylesterase LipT 0.0048 0.0211 0.1628
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0521 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0228 0.0798
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0025 0.0066 0.1858
Echinococcus multilocularis glycogen phosphorylase 0.0465 0.286 0.286
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0269 0.4907
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0521 0.1823
Loa Loa (eye worm) hypothetical protein 0.0049 0.0218 0.0764
Echinococcus granulosus BC026374 protein S09 family 0.0048 0.0211 0.0737
Schistosoma mansoni hypothetical protein 0.008 0.0418 0.1461
Trichomonas vaginalis porcupine, putative 0.0025 0.0066 0.0143
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0032 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0349
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0054
Entamoeba histolytica glycogen phosphorylase, putative 0.0465 0.286 1
Schistosoma mansoni zinc finger protein 0.0025 0.0066 0.023
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.004 0.0296
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0025 0.0066 0.023
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0418 0.0418
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0358 0.2871
Loa Loa (eye worm) carboxylesterase 0.0048 0.0211 0.0737
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.004 0.0052
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0269 0.094
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0358 0.2893
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0269 0.0859
Toxoplasma gondii hypothetical protein 0.0025 0.0066 0.167
Brugia malayi Carboxylesterase family protein 0.0048 0.0211 0.0737
Brugia malayi MBOAT family protein 0.0025 0.0066 0.023
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0201 0.1184 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.01 0.0349
Plasmodium falciparum replication factor C subunit 1, putative 0.005 0.0228 0.9279
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Schistosoma mansoni sterol O-acyltransferase 1 0.0255 0.1527 0.534
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0139
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0104 0.0104
Schistosoma mansoni nAChR subunit 0.0032 0.0108 0.0377
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.004 0.0296
Loa Loa (eye worm) hypothetical protein 0.0053 0.0244 0.0853
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Echinococcus granulosus glycine receptor subunit beta 0.0032 0.0108 0.0377
Brugia malayi intermediate filament protein 0.0026 0.0075 0.0263
Loa Loa (eye worm) hypothetical protein 0.0048 0.0211 0.0737
Leishmania major glycerol uptake protein, putative 0.0025 0.0066 0.0819
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0089 0.0089
Echinococcus multilocularis glycine receptor subunit beta 0.0032 0.0108 0.0108
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.004 0.0127
Schistosoma mansoni hypothetical protein 0.0319 0.1931 0.6752
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0447 0.1564
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0025 0.0066 0.023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0211 0.0737
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0025 0.0066 0.023
Loa Loa (eye worm) MBOAT family protein 0.0025 0.0066 0.023
Schistosoma mansoni hypothetical protein 0.0174 0.101 0.3532
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0108 0.0377
Echinococcus granulosus glycogen phosphorylase 0.0465 0.286 1
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0228 0.0716
Brugia malayi jmjC domain containing protein 0.0035 0.0127 0.0444
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0025 0.0066 0.0066
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.004 0.0158
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.01 0.0349
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.01 0.0349
Trypanosoma cruzi GUP1, putative 0.0025 0.0066 0.0819
Echinococcus granulosus neuroligin 0.0048 0.0211 0.0737
Schistosoma mansoni nAChR subunit 0.0032 0.0108 0.0377
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0025 0.0066 0.0066
Echinococcus granulosus glycine receptor subunit beta 0.0032 0.0108 0.0377
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0025 0.0066 0.023
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.005 0.0228 0.8339
Schistosoma mansoni BC026374 protein (S09 family) 0.0048 0.0211 0.0737
Onchocerca volvulus 0.0026 0.0075 0.0263
Loa Loa (eye worm) hypothetical protein 0.0053 0.0244 0.0853
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0025 0.0066 0.023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0211 0.0737
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0009 0.0032
Schistosoma mansoni nAChR subunit 0.0032 0.0108 0.0377
Echinococcus granulosus tar DNA binding protein 0.0125 0.0698 0.2442
Schistosoma mansoni lamin 0.0026 0.0075 0.0263
Loa Loa (eye worm) hypothetical protein 0.0031 0.0104 0.0363
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0054
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0025 0.0066 0.023
Schistosoma mansoni gliotactin 0.0048 0.0211 0.0737
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0213 0.0663
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0032 0.0108 0.0377
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.01 0.0349
Echinococcus granulosus glycine receptor subunit alpha 1 0.0032 0.0108 0.0377
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0017 0.0016 0.0054
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0097 0.1451
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0089 0.2913
Echinococcus multilocularis survival motor neuron protein 1 0.0462 0.2843 0.2843
Onchocerca volvulus 0.0048 0.0211 0.0737
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0025 0.0066 0.0066
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0061 0.0128
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.023
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0358 0.2871
Leishmania major glycerol uptake protein, putative 0.0025 0.0066 0.0819
Loa Loa (eye worm) hypothetical protein 0.0071 0.0358 0.1251
Echinococcus granulosus GPCR family 2 0.008 0.0418 0.1461
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0025 0.0066 0.0066
Echinococcus multilocularis peregrin 0.0029 0.0089 0.0089
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.01 0.0349
Echinococcus granulosus importin subunit beta 1 0.003 0.0097 0.034
Brugia malayi MBOAT family protein 0.0025 0.0066 0.023
Loa Loa (eye worm) hypothetical protein 0.005 0.0228 0.0798
Loa Loa (eye worm) hypothetical protein 0.0048 0.0211 0.0737
Onchocerca volvulus 0.0017 0.0016 0.0054
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.004 0.0052
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.004 0.0139
Echinococcus multilocularis jumonji domain containing protein 0.004 0.016 0.016
Schistosoma mansoni hypothetical protein 0.0029 0.0089 0.0311
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0025 0.0088
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.004 0.0296
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0269 0.0269
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.004 0.0296
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0358 0.1204
Trichomonas vaginalis ran, putative 0.0022 0.0047 0.0078
Brugia malayi hypothetical protein 0.0016 0.0009 0.0032
Echinococcus granulosus jumonji domain containing protein 0.004 0.016 0.0559
Entamoeba histolytica hypothetical protein, conserved 0.0025 0.0066 0.0177
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0108 0.0377
Trypanosoma cruzi glycerol uptake protein, putative 0.0025 0.0066 0.0819
Onchocerca volvulus Alhambra homolog 0.0029 0.0089 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0228 0.0716
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0358 0.2871
Loa Loa (eye worm) hypothetical protein 0.0089 0.047 0.1644
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0269 1
Trypanosoma brucei glycerol uptake protein, putative 0.0025 0.0066 0.0819
Brugia malayi nuclear receptor RXR 0.0016 0.0009 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0127
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0032 0.0108 0.0108
Echinococcus multilocularis Glycosyl transferase, family 35 0.0465 0.286 0.286
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0032 0.0108 0.0377
Entamoeba histolytica hypothetical protein 0.0024 0.0061 0.0161
Schistosoma mansoni nAChR subunit 0.0032 0.0108 0.0377
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.065 0.2273
Onchocerca volvulus 0.0026 0.0075 0.0263
Schistosoma mansoni topbp1 0.005 0.0228 0.0798
Echinococcus granulosus acetylcholinesterase 0.0282 0.1701 0.5948
Echinococcus multilocularis geminin 0.0334 0.2026 0.2026
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0698 0.0698
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0009 0.0009
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.01 0.0349
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0358 0.1204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0349
Echinococcus multilocularis carboxylesterase 5A 0.0282 0.1701 0.1701
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.01 0.0349
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0349
Loa Loa (eye worm) hypothetical protein 0.0048 0.0211 0.0737
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0698 0.2442
Treponema pallidum DNA ligase (lig) 0.005 0.0228 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0047 0.1004
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0521 0.1751
Schistosoma mansoni hypothetical protein 0.0082 0.0428 0.1496
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.01 0.01
Brugia malayi Pre-SET motif family protein 0.0031 0.0104 0.0363
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.005 0.0228 0.0798
Leishmania major GTP-binding protein, putative 0.0022 0.0047 0.0443
Onchocerca volvulus 0.0103 0.0562 0.1967
Echinococcus granulosus FTZ F1 alpha 0.003 0.01 0.0349
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.004 0.0158
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0418 0.0418
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0054
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0127 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0143
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0025 0.0066 0.167
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.004 0.0139
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.01 0.0349
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0418 0.1461
Echinococcus multilocularis para nitrobenzyl esterase 0.0048 0.0211 0.0211
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0418 0.1461
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0447 0.1564
Echinococcus granulosus nibrin 0.005 0.0228 0.0798
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0358 0.1251
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0108 0.0377
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0358 0.2871
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Brugia malayi excitatory GABA receptor EXP-1A 0.0032 0.0108 0.0377
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.01 0.0349
Schistosoma mansoni ap endonuclease 0.0019 0.0025 0.0088
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0048 0.0211 0.0654
Echinococcus multilocularis FTZ F1 alpha 0.003 0.01 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0104 0.0363
Loa Loa (eye worm) oxidoreductase 0.0021 0.004 0.0139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0104 0.0363
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0269 0.0859
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0521 0.1751
Schistosoma mansoni survival motor neuron protein 0.0094 0.0506 0.1771
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.004 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0127
Loa Loa (eye worm) hypothetical protein 0.0103 0.0562 0.1967
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0127
Loa Loa (eye worm) acetylcholinesterase 1 0.0282 0.1701 0.5948
Trichomonas vaginalis transmembrane protein nessy, putative 0.0025 0.0066 0.0143
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0075 0.0263
Echinococcus granulosus replication factor c subunit 1 0.005 0.0228 0.0798
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0521 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0244 0.0853
Loa Loa (eye worm) glycogen phosphorylase 0.0465 0.286 1
Entamoeba histolytica hypothetical protein 0.0147 0.0843 0.2911
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0032 0.0108 0.0377
Brugia malayi mbt repeat family protein 0.0061 0.0293 0.1024
Loa Loa (eye worm) hypothetical protein 0.0048 0.0211 0.0737
Schistosoma mansoni hypothetical protein 0.0334 0.2026 0.7085
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0048 0.0211 0.1628
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.01 0.0349
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0032 0.0108 0.0377
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0501 0.1753
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.004 0.0602
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0032 0.0108 0.0377
Entamoeba histolytica glycogen phosphorylase, putative 0.0201 0.1184 0.4108
Schistosoma mansoni lamin 0.0026 0.0075 0.0263
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.004 0.0158
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Brugia malayi Carboxylesterase family protein 0.0048 0.0211 0.0737
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0089 0.0311
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0025 0.0066 0.167
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0108 0.0377
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0032 0.0108 0.0377
Echinococcus multilocularis Niemann Pick C1 protein 0.0283 0.1704 0.1704
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0032 0.0108 0.0377
Trypanosoma cruzi glycerol uptake protein, putative 0.0025 0.0066 0.0819
Trypanosoma cruzi glycerol uptake protein, putative 0.0025 0.0066 0.0819
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0349
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.01 0.0349
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.004 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0021 0.004 0.0139
Echinococcus granulosus glycine receptor subunit alpha 1 0.0032 0.0108 0.0377
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0048 0.0211 0.1628
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0025 0.0066 0.023
Brugia malayi Importin beta-1 subunit 0.003 0.0097 0.034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0075 0.0263
Onchocerca volvulus 0.0048 0.0211 0.0737
Trichomonas vaginalis spcc417.12 protein, putative 0.0048 0.0211 0.0654
Loa Loa (eye worm) MBOAT family protein 0.0025 0.0066 0.023
Schistosoma mansoni hypothetical protein 0.0082 0.0428 0.1496
Schistosoma mansoni nAChR subunit 0.0032 0.0108 0.0377
Toxoplasma gondii propionate-CoA ligase 0.0021 0.004 0.0602
Onchocerca volvulus 0.0028 0.0088 0.0307
Onchocerca volvulus 0.0021 0.004 0.0139
Echinococcus granulosus o acyltransferase membrane bound domain 0.0025 0.0066 0.023
Onchocerca volvulus 0.0103 0.0562 0.1967
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0097 0.2957
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0032 0.0108 0.0377
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.005 0.0228 0.0717
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0009 0.0032
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.005 0.0228 0.4092
Echinococcus multilocularis acetylcholinesterase 0.0282 0.1701 0.1701
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0025 0.0066 0.023
Brugia malayi hypothetical protein 0.005 0.0228 0.0798
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0213 0.0663
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0226 0.1757
Loa Loa (eye worm) hypothetical protein 0.005 0.0228 0.0798
Schistosoma mansoni ap endonuclease 0.0019 0.0025 0.0088
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0047 0.0165
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0104 0.3232
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0244 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0047 0.0443
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.004 0.0127
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0009 0.0032
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0069 0.0346 0.121
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0032 0.0108 0.0108
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0244 0.006
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0047 0.0443
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.01 0.0349
Echinococcus multilocularis neuroligin 0.0048 0.0211 0.0211
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0358 0.6703
Echinococcus granulosus snurportin 1 0.0319 0.1931 0.6752
Loa Loa (eye worm) steroid hormone receptor 0.003 0.01 0.0349
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0061 0.0293 0.1024
Onchocerca volvulus 0.0017 0.0016 0.0054
Loa Loa (eye worm) LGC-31 protein 0.0032 0.0108 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0228 0.0716
Echinococcus granulosus intermediate filament protein 0.0026 0.0075 0.0263
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0521 0.1751
Echinococcus multilocularis glycine receptor subunit beta 0.0032 0.0108 0.0108
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.101 0.3532
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0269 0.4907
Brugia malayi MAP kinase sur-1 0.0057 0.0269 0.094
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0698 0.2442
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0127 0.0444
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.004 0.0127
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.004 0.0296
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0158
Echinococcus granulosus expressed conserved protein 0.0186 0.1089 0.3807
Onchocerca volvulus 0.005 0.0228 0.0798
Schistosoma mansoni sex comb on midleg homolog 0.0061 0.0293 0.1024
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0698 0.2442
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0025 0.0032
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0069 0.0346 0.121
Brugia malayi Calcitonin receptor-like protein seb-1 0.0254 0.152 0.5316
Schistosoma mansoni hypothetical protein 0.0025 0.0066 0.023
Loa Loa (eye worm) hypothetical protein 0.0282 0.1701 0.5948
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.01 0.0349
Echinococcus granulosus o acyltransferase membrane bound domain 0.0025 0.0066 0.023
Brugia malayi nuclear receptor NHR-88 0.003 0.01 0.0349
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0127
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0418 0.1461
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.01 0.0349
Brugia malayi Carboxylesterase family protein 0.0048 0.0211 0.0737
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0127 0.0444
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.01 0.01
Schistosoma mansoni glycogen phosphorylase 0.0201 0.1184 0.414
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0254 0.152 0.5316
Loa Loa (eye worm) hypothetical protein 0.0026 0.0072 0.0253
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.004 0.0158
Onchocerca volvulus 0.003 0.01 0.0349
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.005 0.0228 0.0716
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.01 0.0349
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.01 0.0349
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0358 1
Brugia malayi AMP-binding enzyme family protein 0.0021 0.004 0.0139
Brugia malayi Carboxylesterase family protein 0.0282 0.1701 0.5948
Loa Loa (eye worm) hypothetical protein 0.0103 0.0562 0.1967
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Schistosoma mansoni myelin transcription factor 1 myt1 0.0069 0.0346 0.121
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0358 0.6703
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0047 0.1004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.01 0.0349
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0032 0.0108 0.0377
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0025 0.0066 0.023
Onchocerca volvulus 0.0025 0.0066 0.023
Leishmania major hypothetical protein, conserved 0.0025 0.0066 0.0819
Echinococcus multilocularis expressed conserved protein 0.0186 0.1089 0.1089
Schistosoma mansoni transcription factor LCR-F1 0.0147 0.0843 0.295
Loa Loa (eye worm) hhat protein 0.0025 0.0066 0.023
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0097 0.0338
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0104 0.0363
Loa Loa (eye worm) hypothetical protein 0.008 0.0418 0.1461
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0009 0.0032
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.01 0.0349
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Entamoeba histolytica hypothetical protein 0.005 0.0228 0.0748
Echinococcus granulosus lamin 0.0026 0.0075 0.0263
Onchocerca volvulus 0.0032 0.0108 0.0377
Plasmodium vivax replication factor C subunit 1, putative 0.005 0.0228 0.9279
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0447 0.1489
Giardia lamblia Kinase, PLK 0.0097 0.0521 0.1751
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0025 0.0088
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.01 0.0349
Onchocerca volvulus 0.0032 0.0108 0.0377
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0025 0.0066 0.023
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0358 0.1251
Brugia malayi CHE-14 protein 0.0085 0.0447 0.1564
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0032 0.0108 0.0377
Brugia malayi ecdysteroid receptor 0.003 0.01 0.0349
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.01 0.0349
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0032 0.0108 0.0377
Trichomonas vaginalis set domain proteins, putative 0.0245 0.1465 0.5078
Entamoeba histolytica hypothetical protein 0.0147 0.0843 0.2911
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0069 0.0346 0.0346
Onchocerca volvulus 0.0048 0.0211 0.0737
Echinococcus multilocularis sterol O acyltransferase 1 0.0255 0.1527 0.1527
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0017 0.0016 0.0054
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.01 0.0349
Schistosoma mansoni sex comb on midleg homolog 0.0061 0.0293 0.1024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0147 0.0843 0.295
Brugia malayi STAT protein, DNA binding domain containing protein 0.0128 0.0723 0.2528
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0025 0.0066 0.0177
Echinococcus multilocularis glycogen phosphorylase 0.0465 0.286 0.286
Entamoeba histolytica Ran family GTPase 0.0022 0.0047 0.0111
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0269 0.4907
Echinococcus granulosus nAChR subunit 0.0017 0.0016 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0228 0.0716
Echinococcus granulosus para nitrobenzyl esterase 0.0048 0.0211 0.0737
Brugia malayi Hhat protein 0.0025 0.0066 0.023
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0269 0.094
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0201 0.1184 0.4142
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0198 0.1165 0.4041
Loa Loa (eye worm) GABA receptor subunit 0.0017 0.0016 0.0054
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0025 0.0066 0.0066
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.004 0.0139
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.01 0.0349
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0521 0.1751
Onchocerca volvulus 0.0021 0.004 0.0139
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0032 0.0108 0.0377
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0104 0.0104
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.004 0.0139
Schistosoma mansoni hypothetical protein 0.0082 0.0428 0.1496
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0009 0.0032
Schistosoma mansoni thyroid hormone receptor 0.003 0.01 0.0349
Onchocerca volvulus 0.0061 0.0293 0.1024
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0521 0.1823
Brugia malayi Pre-SET motif family protein 0.0215 0.1276 0.4461
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0032 0.0108 0.0377
Echinococcus granulosus Glycosyl transferase family 35 0.0465 0.286 1
Schistosoma mansoni neurotransmitter gated ion channel 0.0017 0.0016 0.0054
Schistosoma mansoni coup transcription factor 0.003 0.01 0.0349
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0032 0.0108 0.0377
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.01 0.01
Brugia malayi Cation transporter family protein 0.0032 0.0108 0.0377
Brugia malayi carbohydrate phosphorylase 0.0465 0.286 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.005 0.0228 0.0717
Echinococcus multilocularis acetylcholinesterase 0.0282 0.1701 0.1701
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0698 0.2442
Echinococcus granulosus SAM and MBT domain containing protein 0.0061 0.0293 0.1024
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.01 0.0349
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Echinococcus granulosus sterol O acyltransferase 1 0.0255 0.1527 0.534
Schistosoma mansoni hypothetical protein 0.008 0.0418 0.1461
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.005 0.0228 1
Brugia malayi RNA binding protein 0.0125 0.0698 0.2442
Loa Loa (eye worm) hypothetical protein 0.023 0.1369 0.4787
Entamoeba histolytica hypothetical protein 0.0147 0.0843 0.2911
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0097 0.1451
Schistosoma mansoni hypothetical protein 0.0372 0.2272 0.7945
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0025 0.0066 0.023
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0244 0.1915
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0127
Trypanosoma brucei protein kinase, putative 0.0057 0.0269 0.4907
Echinococcus multilocularis importin subunit beta 1 0.003 0.0097 0.0097
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0127
Echinococcus granulosus o acyltransferase membrane bound domain 0.0025 0.0066 0.023
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0358 1
Treponema pallidum alginate O-acetylation protein (algI) 0.0025 0.0066 0.2002
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0349
Echinococcus multilocularis protein patched 0.0085 0.0447 0.0447
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0054
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0243 0.1449 0.5066
Loa Loa (eye worm) hypothetical protein 0.005 0.0228 0.0798
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0698 0.2442
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0521 0.1751
Onchocerca volvulus 0.0048 0.0211 0.0737
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0244 0.1889
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.01 0.01
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0032 0.0108 0.0377
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.01 0.0349
Trichomonas vaginalis glycogen phosphorylase, putative 0.0465 0.286 1
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0349
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0243 0.1449 0.1449
Giardia lamblia PHD finger protein 15 0.0029 0.0089 0.0225
Brugia malayi hypothetical protein 0.0016 0.0009 0.0032
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0358 0.1251
Echinococcus multilocularis nAChR subunit 0.0032 0.0108 0.0108
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0269 0.4907
Brugia malayi mbt repeat family protein 0.0061 0.0293 0.1024
Entamoeba histolytica glycogen phosphorylase, putative 0.0465 0.286 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.023
Schistosoma mansoni kinase 0.0049 0.0221 0.0774
Brugia malayi jmjC domain containing protein 0.0093 0.0501 0.1753
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.004 0.0296
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.01 0.0349
Loa Loa (eye worm) hypothetical protein 0.0029 0.0089 0.0311
Brugia malayi MBOAT family protein 0.0025 0.0066 0.023
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0418 0.1461
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.004 0.0127
Loa Loa (eye worm) hypothetical protein 0.0198 0.1165 0.4074
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0009 0.0032
Entamoeba histolytica hypothetical protein 0.0147 0.0843 0.2911
Brugia malayi hypothetical protein 0.0048 0.0211 0.0737
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0698 0.2442
Loa Loa (eye worm) hypothetical protein 0.0061 0.0293 0.1024
Echinococcus multilocularis musashi 0.0026 0.0075 0.0075
Echinococcus multilocularis lamin 0.0026 0.0075 0.0075
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0061 0.0128
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0032 0.0108 0.0377
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0032 0.0108 0.0377
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.065 0.2273
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.01 0.0349
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0254 0.152 0.5316
Schistosoma mansoni intermediate filament proteins 0.0026 0.0075 0.0263
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0048 0.0211 0.0211
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0521 0.1779
Echinococcus multilocularis tumor protein p63 0.0331 0.2009 0.2009
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.004 0.0127
Loa Loa (eye worm) MBCTL1 0.0069 0.0346 0.121
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.01 0.0349
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0025 0.0066 0.0177
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0269 0.094
Echinococcus granulosus nAChR subunit 0.0032 0.0108 0.0377
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0108 0.0377
Echinococcus multilocularis snurportin 1 0.0319 0.1931 0.1931
Echinococcus multilocularis GPCR, family 2 0.008 0.0418 0.0418
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0521 0.1823
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0032
Echinococcus multilocularis histone acetyltransferase MYST2 0.0069 0.0346 0.0346
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.004 0.067
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Loa Loa (eye worm) hypothetical protein 0.0254 0.152 0.5316
Mycobacterium ulcerans hypothetical protein 0.0071 0.0358 0.2871
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0282 0.0986
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0521 0.1751
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0025 0.0066 0.0066
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.004 0.0127
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0158
Trypanosoma cruzi GUP1, putative 0.0025 0.0066 0.0819
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.0349
Brugia malayi Steroid receptor seven-up type 2 0.003 0.01 0.0349
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0143
Loa Loa (eye worm) ACC-1 protein 0.0032 0.0108 0.0377
Schistosoma mansoni thyroid hormone receptor 0.003 0.01 0.0349
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0032 0.0108 0.0377
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0048 0.0211 0.0737
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0244 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0127
Brugia malayi Niemann-Pick C1 protein precursor 0.0198 0.1165 0.4074
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.1931 0.6752
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.004 0.0158
Loa Loa (eye worm) STAT protein 0.0128 0.0723 0.2528
Schistosoma mansoni nAChR subunit 0.0032 0.0108 0.0377
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0032 0.0108 0.0377
Loa Loa (eye worm) MBOAT family protein 0.0025 0.0066 0.023
Onchocerca volvulus 0.0031 0.0104 0.0363
Onchocerca volvulus 0.0245 0.1465 0.5122
Toxoplasma gondii ATPase, AAA family protein 0.005 0.0228 0.8339
Echinococcus multilocularis SAM and MBT domain containing protein 0.0061 0.0293 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0521 0.1823
Chlamydia trachomatis glycogen phosphorylase 0.0465 0.286 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0032
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0032 0.0108 0.0108
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.004 0.0296
Echinococcus multilocularis polycomb protein SCMH1 0.0061 0.0293 0.0293
Echinococcus granulosus geminin 0.0334 0.2026 0.7085
Schistosoma mansoni glycogen phosphorylase 0.0465 0.286 1
Echinococcus multilocularis lamin dm0 0.0026 0.0075 0.0075
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.01 0.0349
Brugia malayi AMP-binding enzyme family protein 0.0021 0.004 0.0139
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.004 0.0158
Loa Loa (eye worm) hypothetical protein 0.0048 0.0215 0.0752
Echinococcus multilocularis nibrin 0.005 0.0228 0.0228
Onchocerca volvulus 0.0094 0.0506 0.1771
Echinococcus granulosus glycine receptor subunit alpha 1 0.0032 0.0108 0.0377
Mycobacterium ulcerans carboxylesterase, LipT 0.0048 0.0211 0.1601
Plasmodium vivax SET domain protein, putative 0.0031 0.0104 0.3596
Brugia malayi hypothetical protein 0.0462 0.2843 0.9944
Trypanosoma brucei polo-like protein kinase 0.0097 0.0521 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0358 0.1204
Schistosoma mansoni DNA ligase IV 0.005 0.0228 0.0798
Echinococcus granulosus acetylcholinesterase 0.0282 0.1701 0.5948
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0061 0.0128
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0215 0.1276 0.4461
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0104 0.0363
Loa Loa (eye worm) hypothetical protein 0.0071 0.0358 0.1251
Schistosoma mansoni importin beta-1 0.003 0.0097 0.034
Onchocerca volvulus 0.0048 0.0211 0.0737
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.023
Loa Loa (eye worm) carboxylesterase 0.0048 0.0211 0.0737
Schistosoma mansoni hypothetical protein 0.0147 0.0843 0.295
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0047 0.0078
Echinococcus multilocularis replication factor c subunit 1 0.005 0.0228 0.0228
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0147 0.0843 0.0843
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Brugia malayi MBOAT family protein 0.0025 0.0066 0.023
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0017 0.0016 0.0054
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.01 0.01
Onchocerca volvulus 0.0048 0.0215 0.0752
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0089 0.2618
Loa Loa (eye worm) hypothetical protein 0.0282 0.1701 0.5948
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0226 0.1757
Schistosoma mansoni hypothetical protein 0.008 0.0418 0.1461
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.01 0.0349
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0032 0.0108 0.0377
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0032
Schistosoma mansoni hypothetical protein 0.0082 0.0428 0.1496
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0521 0.0521
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0025 0.0025
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.005 0.0228 0.0716
Brugia malayi nuclear hormone receptor 0.003 0.01 0.0349
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0358 0.2871
Brugia malayi diacylglycerol acyltransferase 0.0025 0.0066 0.023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0054
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0025 0.0088
Onchocerca volvulus 0.0071 0.0358 0.1251
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0032 0.0108 0.0377
Plasmodium falciparum phd finger protein, putative 0.0029 0.0089 0.2913
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.01 0.0349
Brugia malayi Cation transporter family protein 0.0032 0.0108 0.0377
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0032 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0174 0.101 0.3532
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0054
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0103 0.0562 0.1967
Echinococcus multilocularis nAChR subunit 0.0017 0.0016 0.0016
Giardia lamblia Glycogen phosphorylase 0.0465 0.286 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0048 0.0211 0.0737
Loa Loa (eye worm) hypothetical protein 0.0255 0.1527 0.534
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0025 0.0066 0.023
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.004 0.0086
Schistosoma mansoni hypothetical protein 0.0334 0.2026 0.7085
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0032 0.0108 0.0377
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0032 0.0108 0.0108
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0032 0.0108 0.0377
Loa Loa (eye worm) hypothetical protein 0.005 0.0228 0.0798
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0127 0.0444
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0447 0.0447
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0047 0.0443
Brugia malayi DKFZp564C0469 protein 0.005 0.0228 0.0798
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0032 0.0108 0.0108
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0032 0.0108 0.0377
Loa Loa (eye worm) hypothetical protein 0.0085 0.0447 0.1564
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.004 0.0602
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0047 0.0902
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0025 0.0066 0.023
Schistosoma mansoni nAChR subunit 0.0032 0.0108 0.0377
Echinococcus granulosus histone acetyltransferase MYST2 0.0069 0.0346 0.121
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0032 0.0108 0.0108
Brugia malayi PHD-finger family protein 0.0029 0.0089 0.0311
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.004 0.004
Brugia malayi hypothetical protein 0.0147 0.0843 0.295
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0025 0.0034
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0053 0.0244 0.0853
Loa Loa (eye worm) hypothetical protein 0.0048 0.0211 0.0737
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.01 0.01
Loa Loa (eye worm) ACC-1 protein 0.0032 0.0108 0.0377
Brugia malayi MBOAT family protein 0.0025 0.0066 0.023
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0048 0.0211 0.0737
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.01 0.0349
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0017 0.0016 0.0054
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0032 0.0108 0.0377
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0017 0.0016 0.0054
Trichomonas vaginalis glycogen phosphorylase, putative 0.0465 0.286 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0066 0.0143
Loa Loa (eye worm) RNA binding protein 0.0125 0.0698 0.2442
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0032 0.0108 0.0108
Loa Loa (eye worm) hhat protein 0.0025 0.0066 0.023
Loa Loa (eye worm) carboxylesterase 0.0282 0.1701 0.5948
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.0506 0.1771
Echinococcus multilocularis BC026374 protein (S09 family) 0.0048 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0104 0.0569 0.1988
Brugia malayi hypothetical protein 0.005 0.0228 0.0798
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0377
Loa Loa (eye worm) hypothetical protein 0.0069 0.0346 0.121
Schistosoma mansoni ran 0.0022 0.0047 0.0165
Onchocerca volvulus 0.0032 0.0108 0.0377
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0032 0.0108 0.0108
Echinococcus granulosus Niemann Pick C1 protein 0.0198 0.1165 0.4074
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0358 0.2871
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.01 0.0349
Brugia malayi topoisomerase 0.005 0.0228 0.0798
Brugia malayi Bromodomain containing protein 0.0029 0.0089 0.0311
Trichomonas vaginalis replication factor C large subunit, putative 0.005 0.0228 0.0717
Entamoeba histolytica hypothetical protein 0.0025 0.0066 0.0177
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0358 0.2871
Plasmodium falciparum importin beta, putative 0.003 0.0097 0.329
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.01 0.0349

Activities

Activity type Activity value Assay description Source Reference
Fold change (functional) = 2.4 Agonist activity at human recombinant PPARgamma at 30 uM by GAL4 transactivation assay relative to control ChEMBL. 17187904
Fold change (functional) = 4.6 Agonist activity at human recombinant PPARalpha at 50 uM by GAL4 transactivation assay relative to control ChEMBL. 17187904
Fold change (functional) = 2.4 Agonist activity at human recombinant PPARgamma at 30 uM by GAL4 transactivation assay relative to control ChEMBL. 17187904
Fold change (functional) = 4.6 Agonist activity at human recombinant PPARalpha at 50 uM by GAL4 transactivation assay relative to control ChEMBL. 17187904

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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