Detailed information for compound 446249

Basic information

Technical information
  • TDR Targets ID: 446249
  • Name: 1-(3-azidopropyl)-5-methoxyindole
  • MW: 230.266 | Formula: C12H14N4O
  • H donors: 0 H acceptors: 0 LogP: 3.17 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: [N-]=[N+]=NCCCn1ccc2c1ccc(c2)OC
  • InChi: 1S/C12H14N4O/c1-17-11-3-4-12-10(9-11)5-8-16(12)7-2-6-14-15-13/h3-5,8-9H,2,6-7H2,1H3
  • InChiKey: AGAOFAFOFGRIFT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(3-azidopropyl)-5-methoxy-indole

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0048 0.0254 0.1243
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Schistosoma mansoni hypothetical protein 0.0019 0.0083 0.0408
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0047 0.0251 0.3605
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0047 0.0251 0.1004
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0014 0.0199
Plasmodium vivax serine/threonine protein phosphatase PP1, putative 0.0033 0.0165 0.4654
Echinococcus granulosus protein phosphatase 2c 0.0014 0.0053 0.0257
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme 0.0033 0.0165 0.0809
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0008 0.0014 0.0199
Schistosoma mansoni coup transcription factor 0.002 0.0089 0.0435
Schistosoma mansoni ap endonuclease 0.0012 0.0036 0.0178
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0029 0.014 0.0686
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0061 0.0329 0.4739
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0057 0.0814
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0038 0.0553
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0025 0.0025
Trichomonas vaginalis penicillin-binding protein, putative 0.0048 0.0254 0.3658
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0048 0.0254 0.0229
Brugia malayi phosphofructokinase 0.0067 0.0367 0.1982
Mycobacterium ulcerans sulfatase 0.0011 0.0036 0.001
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme 0.0033 0.0165 0.0167
Toxoplasma gondii LsmAD domain-containing protein 0.0016 0.006 0.2296
Schistosoma mansoni survival motor neuron protein 0.0064 0.0352 0.172
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0017 0.0066 0.0323
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0031 0.0155 0.2226
Echinococcus multilocularis geminin 0.0348 0.2044 0.2064
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0028 0.0133 0.1908
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0123 0.1765
Schistosoma mansoni zinc finger protein 0.001 0.0025 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0067 0.0367 0.5281
Echinococcus multilocularis Ankyrin 0.0009 0.0021 0.0021
Echinococcus granulosus 6 phosphofructokinase 0.0067 0.0367 0.1795
Trypanosoma brucei DNA polymerase IV, putative 0.003 0.0144 0.2065
Brugia malayi ImpB/MucB/SamB family protein 0.001 0.0029 0.0159
Echinococcus granulosus tumor protein p63 0.0208 0.121 0.5917
Trichomonas vaginalis phosphofructokinase, putative 0.0067 0.0367 0.5281
Trichomonas vaginalis phosphofructokinase, putative 0.0067 0.0367 0.5281
Loa Loa (eye worm) serine/threonine protein phosphatase 2A 0.0122 0.0695 0.2786
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0061 0.0334 0.1804
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0028 0.0133 0.1908
Leishmania major serine/threonine protein phosphatase type 5, putative 0.0046 0.0239 0.3441
Trypanosoma brucei DNA polymerase IV, putative 0.0025 0.0115 0.1658
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0025 0.0355
Schistosoma mansoni protein phosphatase-1 0.0033 0.0165 0.0809
Echinococcus multilocularis Niemann Pick C1 protein 0.0061 0.0329 0.0332
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0.002 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Brugia malayi 6-phosphofructokinase 0.0067 0.0367 0.1982
Toxoplasma gondii ABC1 family protein 0.0048 0.0254 1
Brugia malayi Bloom's syndrome protein homolog 0.0013 0.0046 0.0247
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0254 0.7249
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0021 0.0092 0.0368
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0009 0.0021 0.0101
Mycobacterium tuberculosis Conserved protein 0.0048 0.0254 0.0229
Schistosoma mansoni nuclear hormone receptor 0.002 0.0089 0.0435
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0018 0.0075 0.2021
Brugia malayi acetyltransferase, GNAT family protein 0.0089 0.05 0.2702
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0025 0.0121
Schistosoma mansoni protein phosphatase 2C 0.0097 0.0543 0.2658
Onchocerca volvulus 0.0048 0.0254 0.3658
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0254 0.3658
Schistosoma mansoni nuclear receptor 0.001 0.0025 0.0121
Echinococcus multilocularis jun protein 0.0029 0.014 0.0141
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.002 0.0089 0.0064
Schistosoma mansoni hypothetical protein 0.0025 0.0117 0.0573
Brugia malayi ecdysone receptor 0.001 0.0025 0.0133
Onchocerca volvulus Putative protein phosphatase 2C 0.0014 0.0053 0.0756
Loa Loa (eye worm) hypothetical protein 0.0022 0.0101 0.0404
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0014 0.0199
Onchocerca volvulus 0.002 0.0089 0.1278
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0048 0.0254 0.1243
Schistosoma mansoni inositol monophosphatase 0.0023 0.0103 0.0504
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0089 0.0435
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Echinococcus multilocularis transfer RNA-Lys 0.0022 0.01 0.0101
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.0014 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0178 0.0714
Echinococcus granulosus dna polymerase eta 0.001 0.0029 0.0144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0066 0.0951
Entamoeba histolytica acetyltransferase, GNAT family 0.0024 0.0111 0.1597
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0021 0.0092 0.132
Mycobacterium ulcerans isocitrate lyase Icl 0.1681 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.009 0.1298
Loa Loa (eye worm) phosphofructokinase 0.0067 0.0367 0.1471
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0025 0.0099
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0033 0.0165 0.0167
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0089 0.0435
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0089 0.0435
Toxoplasma gondii exonuclease III APE 0.0012 0.0036 0.1362
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0012 0.0036 0.0886
Brugia malayi ecdysteroid receptor 0.002 0.0089 0.048
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.001 0.0025 0.0026
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.001 0.0029 0.0118
Mycobacterium tuberculosis Possible hydrolase 0.0011 0.0036 0.001
Schistosoma mansoni hypothetical protein 0.0019 0.0083 0.0408
Echinococcus granulosus Ankyrin 0.0009 0.0021 0.0101
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0089 0.009
Echinococcus multilocularis isocitrate dehydrogenase 0.001 0.0025 0.0026
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.0014 0.0053 0.0257
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.1019
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0009 0.002 0.0099
Loa Loa (eye worm) hypothetical protein 0.0316 0.1851 0.7421
Trypanosoma cruzi DNA polymerase kappa, putative 0.003 0.0144 0.2065
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0064 0.0348 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0023 0.0103 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0026 0.0123 0.0492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0089 0.0356
Brugia malayi hypoxia-induced factor 1 0.0093 0.0521 0.2814
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0066 0.0951
Loa Loa (eye worm) RecQ helicase 0.0013 0.0046 0.0184
Brugia malayi hypothetical protein 0.0162 0.0937 0.5062
Echinococcus multilocularis beta LACTamase domain containing family member 0.0048 0.0254 0.0257
Loa Loa (eye worm) MH2 domain-containing protein 0.0074 0.0406 0.1629
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0021 0.0092 0.132
Trypanosoma brucei protein kinase, putative 0.0031 0.0155 0.2226
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0064 0.0348 0.1881
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0216 0.1256 0.6784
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0008 0.0016 0.0223
Echinococcus multilocularis transcription factor Dp 1 0.0027 0.0131 0.0132
Echinococcus multilocularis netrin receptor unc 5 0.0009 0.002 0.002
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0026 0.0124 0.4837
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0017 0.0066 0.0951
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0018 0.0075 0.2021
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0026 0.0102
Trichomonas vaginalis guanylate cyclase, putative 0.0008 0.0014 0.0199
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.001 0.0025 0.0026
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0089 0.0435
Schistosoma mansoni cellular tumor antigen P53 0.003 0.0149 0.073
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0048 0.0254 0.1373
Brugia malayi hypothetical protein 0.0011 0.0032 0.017
Entamoeba histolytica serine/threonine protein phosphatase PP1, putative 0.0021 0.0092 0.132
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.001 0.0029 0.0144
Schistosoma mansoni lamin 0.0036 0.0182 0.0891
Mycobacterium tuberculosis Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) 0.1681 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0089 0.009
Brugia malayi conserved hypotetical protein 0.001 0.0025 0.0133
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1665 0.9907 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0018 0.0075 0.1175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0023 0.0327
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0025 0.0121
Schistosoma mansoni transcription factor LCR-F1 0.0022 0.01 0.0487
Echinococcus multilocularis Serine threonine specific protein phosphatase bis(5 nucleosyl) tetraphosphatase 0.0014 0.0053 0.0053
Echinococcus granulosus protein phosphatase pp2a regulatory subunit b 0.0122 0.0695 0.3399
Trypanosoma brucei protein phosphatase 1 0.0021 0.0092 0.132
Echinococcus multilocularis protein phosphatase 2C 0.0014 0.0053 0.0053
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0089 0.048
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0126
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Toxoplasma gondii hypothetical protein 0.0017 0.0066 0.2537
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0057 0.0814
Loa Loa (eye worm) hypoxia-induced factor 1 0.0093 0.0521 0.2088
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0026 0.0124 0.3446
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0028 0.0133 0.1908
Echinococcus granulosus Niemann Pick C1 protein 0.0061 0.0329 0.1611
Giardia lamblia Hypothetical protein 0.0011 0.0036 0.0514
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0011 0.0036 0.0514
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0105 0.0595 0.2383
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Giardia lamblia Histone acetyltransferase GCN5 0.0024 0.0111 0.1597
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0033 0.0165 0.238
Trypanosoma brucei protein phosphatase 2A regulatory subunit, putative 0.0122 0.0695 1
Toxoplasma gondii phosphofructokinase PFKII 0.0018 0.0075 0.2903
Trichomonas vaginalis adenylate cyclase, putative 0.0008 0.0014 0.0199
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0012 0.0036 0.0011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0089 0.048
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0021 0.0092 0.0368
Plasmodium vivax 6-phosphofructokinase, putative 0.0018 0.0075 0.2021
Leishmania major DNA polymerase kappa, putative 0.0015 0.0058 0.0831
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0029 0.0143
Trichomonas vaginalis esterase, putative 0.0048 0.0254 0.3658
Brugia malayi Intermediate filament tail domain containing protein 0.0036 0.0182 0.0984
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0017 0.0066 0.0951
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0032 0.0154
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0025 0.0025
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0028 0.0133 0.1908
Brugia malayi RNA recognition motif domain containing protein 0.0046 0.0239 0.1292
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0089 0.048
Mycobacterium ulcerans esterase/lipase LipP 0.0048 0.0254 0.0229
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0103 0.1484
Echinococcus granulosus nuclear factor of activated T cells 5 0.0045 0.0238 0.1165
Entamoeba histolytica recQ family helicase, putative 0.0007 0.0009 0.0133
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0021 0.0092 0.132
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0022 0.0099 0.1423
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0067 0.0367 0.5281
Loa Loa (eye worm) hypothetical protein 0.001 0.0029 0.0118
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0032 0.0126
Brugia malayi Protein phosphatase 2C containing protein 0.0014 0.0053 0.0284
Echinococcus multilocularis survival motor neuron protein 1 0.0316 0.1851 0.1869
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0012 0.0036 0.0886
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0045 0.0238 0.024
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0089 0.0435
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0089 0.009
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0032 0.017
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0356
Schistosoma mansoni hypothetical protein 0.0009 0.002 0.0099
Echinococcus multilocularis mitogen activated protein kinase 3 0.0031 0.0155 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0057 0.0814
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.0155 0.2226
Mycobacterium ulcerans hydrolase 0.0011 0.0036 0.001
Loa Loa (eye worm) 6-phosphofructokinase 0.0067 0.0367 0.1471
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.001 0.0025 0.0563
Trichomonas vaginalis serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform, putative 0.0122 0.0695 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0023 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0089 0.048
Mycobacterium tuberculosis Probable esterase LipL 0.0048 0.0254 0.0229
Leishmania major hypothetical protein, conserved 0.0016 0.006 0.0864
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0015 0.0058 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0356
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.1421
Schistosoma mansoni nuclear hormone receptor 0.001 0.0025 0.0121
Loa Loa (eye worm) CYP4Cod1 0.001 0.0026 0.0102
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.001 0.0025 0.0366
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0216 0.1256 0.6144
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0064 0.0348 0.5012
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0008 0.0014 0.0068
Schistosoma mansoni hypothetical protein 0.0032 0.0157 0.077
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0089 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Brugia malayi hypothetical protein 0.0316 0.1851 1
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0356
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0126
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0033 0.0165 0.238
Loa Loa (eye worm) protein phosphatase 2C containing protein 0.011 0.0627 0.2513
Echinococcus multilocularis expressed conserved protein 0.0057 0.0307 0.031
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0009 0.0023 0.0327
Trypanosoma brucei serine/threonine protein phosphatase 2A regulatory subunit, putative 0.0007 0.0006 0.0089
Brugia malayi cytoplasmic intermediate filament protein 0.0019 0.0082 0.0445
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0064 0.0348 0.5012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0012 0.0168
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0025 0.0121
Echinococcus multilocularis dna polymerase kappa 0.003 0.0144 0.0145
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0017 0.0071 0.0072
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0028 0.0133 0.0648
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0032 0.0154
Trichomonas vaginalis protein phosphatase-1, putative 0.0028 0.0132 0.1903
Schistosoma mansoni hypothetical protein 0.0025 0.0117 0.0573
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0033 0.0165 0.0893
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0031 0.0155 0.2226
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0009 0.0023 0.0023
Mycobacterium ulcerans 6-phosphofructokinase 0.0067 0.0367 0.0342
Plasmodium falciparum ataxin-2 like protein, putative 0.0016 0.006 0.1574
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0089 0.0435
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0211
Schistosoma mansoni hypothetical protein 0.0025 0.0117 0.0573
Brugia malayi follicle stimulating hormone receptor 0.0105 0.0595 0.3212
Mycobacterium tuberculosis Isocitrate lyase Icl (isocitrase) (isocitratase) 0.1681 1 1
Brugia malayi hypothetical protein 0.001 0.0025 0.0133
Onchocerca volvulus 0.001 0.0025 0.0355
Brugia malayi hypothetical protein 0.0022 0.01 0.0538
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0014 0.0053 0.0757
Entamoeba histolytica serine/threonine protein phosphatase PP1-2, putative 0.0014 0.0053 0.0757
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0022 0.0099 0.1423
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0013 0.0045 0.0654
Loa Loa (eye worm) hypothetical protein 0.003 0.0149 0.0598
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0089 0.0435
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0047 0.025 0.3591
Trichomonas vaginalis bromodomain-containing protein, putative 0.0026 0.0124 0.1785
Echinococcus granulosus intermediate filament protein 0.0036 0.0182 0.0891
Echinococcus multilocularis lamin dm0 0.0036 0.0182 0.0184
Echinococcus granulosus survival motor neuron protein 1 0.0316 0.1851 0.9056
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0025 0.0099
Trichomonas vaginalis phosphofructokinase, putative 0.0067 0.0367 0.5281
Entamoeba histolytica phosphofructokinase, putative 0.0067 0.0367 0.5281
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0062 0.0335 0.1638
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0009 0.0023 0.0111
Onchocerca volvulus 0.0048 0.0254 0.3658
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0356
Plasmodium falciparum ataxin-2 like protein, putative 0.0016 0.006 0.1574
Loa Loa (eye worm) intermediate filament protein 0.0036 0.0182 0.073
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0089 0.0356
Schistosoma mansoni protein phosphatase-1 0.0021 0.0092 0.0449
Trypanosoma brucei hypothetical protein, conserved 0.0122 0.0695 1
Echinococcus granulosus death domain containing protein 0.0009 0.002 0.0099
Leishmania major hypothetical protein, conserved 0.0122 0.0695 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0075 0.1073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.1908
Echinococcus multilocularis Serine:threonine protein phosphatase 2A 65 kDa 0.0007 0.0006 0.0006
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0023 0.0103 0.4007
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0009 0.002 0.002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0015 0.0058 0.0831
Schistosoma mansoni jun-related protein 0.0024 0.0108 0.0527
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0036 0.0525
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0025 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0066 0.0951
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0356
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0009 0.002 0.0081
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0008 0.0016 0.0223
Loa Loa (eye worm) hypothetical protein 0.0017 0.0071 0.0285
Echinococcus multilocularis Niemann Pick C1 protein 0.0087 0.0485 0.0489
Entamoeba histolytica hypothetical protein 0.0022 0.01 0.1433
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0089 0.0435
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0011 0.0036 0.0517
Mycobacterium ulcerans arylsulfatase AtsB 0.0011 0.0036 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0083 0.0408
Schistosoma mansoni serine/threonine protein phosphatase 2a regulatory subunit A 0.0008 0.0014 0.0071
Plasmodium falciparum protein phosphatase PPM2 0.0014 0.0053 0.1355
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0089 0.048
Echinococcus multilocularis GPCR, family 2 0.0019 0.0083 0.0084
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Echinococcus granulosus GPCR family 2 0.0019 0.0083 0.0408
Trypanosoma cruzi serine/threonine protein phosphatase 2A regulatory subunit, putative 0.0008 0.0014 0.0208
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0017 0.0066 0.0323
Schistosoma mansoni tar DNA-binding protein 0.0046 0.0239 0.117
Brugia malayi steroid hormone receptor 0.002 0.0089 0.048
Loa Loa (eye worm) hypothetical protein 0.0036 0.0182 0.073
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0089 0.009
Schistosoma mansoni DNA polymerase eta 0.001 0.0029 0.0144
Brugia malayi MAP kinase sur-1 0.0031 0.0155 0.0836
Brugia malayi tailless protein 0.001 0.0025 0.0133
Onchocerca volvulus Netrin receptor homolog 0.0009 0.002 0.0291
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0103 0.1484
Loa Loa (eye worm) hypothetical protein 0.0009 0.0021 0.0083
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0018 0.0075 1
Brugia malayi hypothetical protein 0.001 0.0025 0.0133
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0103 0.1484
Brugia malayi probable protein phosphatase 2C 0.0014 0.0053 0.0284
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0026 0.0124 0.4837
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.1908
Giardia lamblia Kinase, CMGC MAPK 0.0031 0.0155 0.2226
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0031 0.0155 0.2226
Mycobacterium ulcerans arylsulfatase AtsD 0.0011 0.0036 0.001
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0023 0.0103 0.0078
Onchocerca volvulus 0.0036 0.0182 0.2622
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0018 0.0075 0.1084
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Loa Loa (eye worm) cytochrome P450 family protein 0.001 0.0026 0.0102
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0025 0.0099
Echinococcus multilocularis bloom syndrome protein 0.0013 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.1019
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0199
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0089 0.009
Echinococcus granulosus protein phosphatase 5 0.0046 0.0239 0.117
Schistosoma mansoni serine/threonine protein phosphatase 2a regulatory subunit A 0.0011 0.0035 0.0173
Echinococcus multilocularis mitogen activated protein kinase 0.0031 0.0155 0.0156
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0008 0.0014 0.0199
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 0.0033 0.0165 0.0893
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.0155 0.2226
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0019 0.0082 0.033
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0011 0.0036 0.001
Loa Loa (eye worm) hypothetical protein 0.0423 0.2495 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0126
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.001 0.0025 0.0366
Schistosoma mansoni intermediate filament proteins 0.0036 0.0182 0.0891
Schistosoma mansoni thyroid hormone receptor 0.002 0.0089 0.0435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0056 0.0812
Echinococcus multilocularis protein phosphatase 2C 0.0014 0.0053 0.0053
Trichomonas vaginalis protein phosphatase pp2a regulatory subunit B, putative 0.0122 0.0695 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.001 0.0025 0.0366
Mycobacterium ulcerans DNA polymerase IV 0.003 0.0144 0.0118
Schistosoma mansoni 6-phosphofructokinase 0.0067 0.0367 0.1795
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0089 0.0356
Trypanosoma cruzi DNA polymerase eta, putative 0.001 0.0029 0.0423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.1421
Giardia lamblia Phosphatase 0.0014 0.0053 0.0757
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0047 0.0251 0.3605
Mycobacterium ulcerans putative regulatory protein 0.0022 0.01 0.0074
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0011 0.0036 0.0514
Mycobacterium tuberculosis Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) 0.1681 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0075 0.1084
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0083 0.045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0065 0.0937
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0009 0.0023 0.0327
Schistosoma mansoni hypothetical protein 0.0025 0.0117 0.0573
Echinococcus multilocularis protein phosphatase 1b 0.011 0.0627 0.0633
Entamoeba histolytica deoxycytidyl transferase, putative 0.001 0.0029 0.0423
Loa Loa (eye worm) hypothetical protein 0.0017 0.0067 0.0269
Echinococcus multilocularis tumor protein p63 0.0208 0.121 0.1221
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0089 0.1278
Loa Loa (eye worm) hypothetical protein 0.0033 0.0165 0.0663
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.0155 0.2226
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0023 0.0327
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0025 0.0025
Brugia malayi Calcitonin receptor-like protein seb-1 0.0061 0.0334 0.1804
Leishmania major protein kinase, putative 0.0008 0.0016 0.0223
Trypanosoma brucei cytochrome P450, putative 0.001 0.0026 0.0368
Echinococcus multilocularis protein dispatched 1 0.003 0.0145 0.0146
Leishmania major hypothetical protein, conserved 0.0048 0.0254 0.3658
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0103 0.1484
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0032 0.017
Onchocerca volvulus 0.0036 0.0182 0.2622
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0023 0.0103 0.1484
Trypanosoma brucei serine/threonine protein phosphatase 2A regulatory subunit, putative 0.0007 0.0006 0.0089
Echinococcus multilocularis 6 phosphofructokinase 0.0067 0.0367 0.037
Toxoplasma gondii protein phosphatase 2C domain-containing protein 0.0014 0.0053 0.1999
Entamoeba histolytica phosphofructokinase, putative 0.0067 0.0367 0.5281
Schistosoma mansoni serine/threonine protein phosphatase 2a regulatory subunit A 0.001 0.0027 0.0132
Schistosoma mansoni hypothetical protein 0.0348 0.2044 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0307 0.18 0.1779
Brugia malayi Serine/threonine protein phosphatase PP1 isozyme 1, putative 0.0021 0.0092 0.0496
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0048 0.0254 0.0229
Loa Loa (eye worm) 6-phosphofructokinase 0.0067 0.0367 0.1471
Loa Loa (eye worm) isocitrate dehydrogenase 0.001 0.0025 0.0102
Onchocerca volvulus 0.0017 0.0066 0.0951
Brugia malayi latrophilin 2 splice variant baaae 0.0042 0.0218 0.1177
Trypanosoma cruzi DNA polymerase kappa, putative 0.003 0.0144 0.2065
Schistosoma mansoni protein phosphatase type 1 0.0033 0.0165 0.0809
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0695 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.001 0.0025 0.0366
Trypanosoma brucei DNA polymerase IV, putative 0.003 0.0144 0.2065
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0047 0.0251 0.3605
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0089 0.048
Echinococcus granulosus expressed conserved protein 0.0057 0.0307 0.1504
Schistosoma mansoni ap endonuclease 0.0012 0.0036 0.0178
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0075 0.1084
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0028 0.0133 0.1908
Onchocerca volvulus Protein phosphatase PP2A 55 kDa regulatory subunit homolog 0.0122 0.0695 1
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0064 0.0348 0.0352
Echinococcus multilocularis inositol monophosphatase 1 0.0023 0.0103 0.0104
Trichomonas vaginalis penicillin-binding protein, putative 0.0048 0.0254 0.3658
Schistosoma mansoni patched 1 0.0026 0.0123 0.06
Schistosoma mansoni ankyrin 23/unc44 0.0009 0.002 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.009 0.1298
Mycobacterium ulcerans lipase LipD 0.0048 0.0254 0.0229
Loa Loa (eye worm) hypothetical protein 0.001 0.003 0.012
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0033 0.0165 0.0809
Loa Loa (eye worm) hypothetical protein 0.0061 0.0329 0.132
Trichomonas vaginalis serine/threonine protein phosphatase 2A regulatory subunit A, putative 0.0008 0.0014 0.0208
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0356
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0047 0.0251 0.1353
Echinococcus multilocularis dna polymerase eta 0.001 0.0029 0.003
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0067 0.0367 1
Leishmania major protein phosphatase 2A regulatory subunit, putative 0.0122 0.0695 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0089 0.05 0.0505
Loa Loa (eye worm) protein phosphatase 5 0.0044 0.0228 0.0912
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0012 0.0036 0.088
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0025 0.0355
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative 0.0033 0.0165 0.238
Trypanosoma cruzi serine/threonine protein phosphatase type 5, putative 0.0048 0.0253 0.3648
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0089 0.048
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0025 0.0133
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.001 0.0025 0.0124
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.003 0.0144 0.2065
Onchocerca volvulus 0.0008 0.0014 0.0199
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0008 0.0016 0.0223
Schistosoma mansoni hypothetical protein 0.0024 0.0108 0.0527
Echinococcus granulosus serine:threonine protein phosphatase 0.0012 0.0041 0.02
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0007 0.0009 0.0133
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0025 0.0121
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0018 0.0075 0.1084
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative 0.0033 0.0165 0.238
Brugia malayi polk-prov protein 0.0022 0.0101 0.0544
Trypanosoma brucei unspecified product 0.0007 0.001 0.0146
Brugia malayi Serine/threonine protein phosphatase PP1-gamma catalytic subunit 0.0021 0.0092 0.0496
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0066 0.0951
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0027 0.0128 0.0627
Brugia malayi putative serine/threonine phosphatase 0.0021 0.0092 0.0496
Giardia lamblia Ser/Thr protein phosphatase PP1-alpha 2 catalytic subunit 0.0033 0.0165 0.238
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0089 0.0356
Echinococcus granulosus single minded 2 0.0022 0.01 0.0488
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Mycobacterium tuberculosis Probable hydrolase 0.0048 0.0254 0.0229
Brugia malayi hypothetical protein 0.0011 0.0032 0.017
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0028 0.0133 0.0648
Toxoplasma gondii serine/threonine protein phosphatase 0.0046 0.0239 0.9404
Toxoplasma gondii serine/threonine phosophatase PP1 0.0033 0.0165 0.6478
Trichomonas vaginalis protein phosphatase-1, putative 0.0021 0.0092 0.132
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0008 0.0014 0.0014
Brugia malayi TAR-binding protein 0.0046 0.0239 0.1292
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0155 0.0757
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0089 0.0356
Echinococcus multilocularis Serine threonine specific protein phosphatase bis(5 nucleosyl) tetraphosphatase 0.0014 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trichomonas vaginalis D-aminoacylase, putative 0.0048 0.0254 0.3658
Entamoeba histolytica hypothetical protein 0.0022 0.01 0.1433
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0695 1
Brugia malayi hypothetical protein 0.0101 0.0567 0.3065
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0067 0.0367 0.0342
Leishmania major protein phosphatase 2C-like protein 0.0014 0.0053 0.0756
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0012 0.0036 0.0525
Giardia lamblia Rab geranylgeranyltransferase 0.0064 0.0348 0.5012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0074 0.0298
Trypanosoma cruzi protein phosphatase 2A regulatory subunit, putative 0.0122 0.0695 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0061 0.0334 0.1338
Echinococcus granulosus lamin 0.0036 0.0182 0.0891
Trypanosoma brucei serine/threonine protein phosphatase 5 0.0048 0.0253 0.3648
Mycobacterium tuberculosis Conserved hypothetical protein 0.001 0.0029 0.0004
Trichomonas vaginalis serine/threonine protein phosphatase 2A regulatory subunit A, putative 0.0007 0.0006 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Echinococcus granulosus FTZ F1 alpha 0.002 0.0089 0.0435
Trichomonas vaginalis phosphofructokinase, putative 0.0067 0.0367 0.5281
Plasmodium falciparum serine/threonine protein phosphatase PP1 0.0033 0.0165 0.4654
Brugia malayi nuclear hormone receptor 0.001 0.0025 0.0133
Mycobacterium ulcerans DNA polymerase IV 0.003 0.0144 0.0118
Trichomonas vaginalis DNA polymerase eta, putative 0.003 0.0144 0.2065
Brugia malayi hypothetical protein 0.0011 0.0036 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.1421
Trichomonas vaginalis inositol monophosphatase, putative 0.0023 0.0103 0.1484
Loa Loa (eye worm) phosphatidylinositol 3 0.0028 0.0133 0.0531
Loa Loa (eye worm) serine/threonine protein phosphatase PP1 isozyme 1 0.0021 0.0092 0.0368
Loa Loa (eye worm) hypothetical protein 0.0101 0.0567 0.2274
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0025 0.0133
Schistosoma mansoni protein phosphatase type 1 0.0033 0.0165 0.0809
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0075 0.1084
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0023 0.0103 0.1484
Loa Loa (eye worm) inositol-1 0.0023 0.0103 0.0413
Brugia malayi bZIP transcription factor family protein 0.0029 0.014 0.0757
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Echinococcus multilocularis sterol regulatory element binding protein 0.0026 0.0123 0.0124
Plasmodium vivax protein phosphatase PPM2, putative 0.0014 0.0053 0.1355
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0211
Brugia malayi Isocitrate dehydrogenase 0.001 0.0025 0.0137
Schistosoma mansoni inositol monophosphatase 0.0023 0.0103 0.0504
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0058 0.0831
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0064 0.0348 0.1396
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Mycobacterium tuberculosis Probable sulfatase 0.0011 0.0036 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0056 0.0812
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.009 0.1298
Loa Loa (eye worm) hypothetical protein 0.0009 0.002 0.0081
Schistosoma mansoni hypothetical protein 0.0022 0.01 0.0487
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.1019
Brugia malayi nuclear receptor NHR-67 0.001 0.0025 0.0133
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0012 0.0036 0.0178
Giardia lamblia Phosphatase 0.0014 0.0053 0.0756
Brugia malayi Serine/threonine protein phosphatase PP1 isozyme 1, putative 0.0021 0.0092 0.0496
Entamoeba histolytica protein phosphatase, putative 0.0028 0.0132 0.1903
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0032 0.0032
Echinococcus multilocularis tar DNA binding protein 0.0046 0.0239 0.0241
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0064 0.0348 1
Schistosoma mansoni netrin receptor unc5 0.0009 0.002 0.0099
Schistosoma mansoni terminal deoxycytidyl transferase 0.001 0.0029 0.0144
Brugia malayi Cytochrome P450 family protein 0.001 0.0026 0.0138
Trypanosoma brucei DNA polymerase eta, putative 0.001 0.0029 0.0423
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0012 0.0036 0.0037
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0008 0.0014 0.0199
Echinococcus multilocularis protein phosphatase pp2a regulatory subunit b 0.0122 0.0695 0.0701
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0065 0.0937
Schistosoma mansoni protein phosphatase-5 0.0048 0.0253 0.124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0066 0.0951
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0083 0.0084
Trichomonas vaginalis protein phosphatase-1, putative 0.0021 0.0092 0.132
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0048 0.0254 0.0229
Brugia malayi PAS domain containing protein 0.003 0.0146 0.079
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0089 0.0435
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0012 0.0036 0.0011
Mycobacterium tuberculosis Conserved protein 0.0048 0.0254 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0011 0.0036 0.001
Mycobacterium tuberculosis Probable lipase LipD 0.0048 0.0254 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.009 0.1298
Brugia malayi serine/threonine protein phosphatase 2A 0.0122 0.0695 0.3754
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0009 0.0023 0.0327
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0018 0.0075 0.2903
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0017 0.0066 0.1752
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0028 0.0133 0.1908
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0047 0.0251 0.0253
Toxoplasma gondii 6-phosphofructokinase 0.0018 0.0075 0.2903
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0028 0.0133 0.0716
Loa Loa (eye worm) hypothetical protein 0.0061 0.0334 0.1338
Loa Loa (eye worm) hypothetical protein 0.0032 0.0158 0.0632
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.1449
Echinococcus granulosus tar DNA binding protein 0.0046 0.0239 0.117
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0033 0.0165 0.0809
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0199
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0028 0.0133 0.1908
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0008 0.0014 0.0199
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0046 0.0239 0.0958
Trypanosoma brucei protein phosphatase 1 0.0021 0.0092 0.132
Leishmania major protein kinase, putative 0.0008 0.0016 0.0223
Echinococcus granulosus protein phosphatase 2c 0.0014 0.0053 0.0257
Loa Loa (eye worm) hypothetical protein 0.0017 0.0067 0.0269
Trypanosoma cruzi DNA polymerase kappa, putative 0.003 0.0144 0.2065
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0216 0.1256 0.6144
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0002 0.0031
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0017 0.0066 0.0951
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta 0.0033 0.0165 0.0167
Loa Loa (eye worm) phosphatidylinositol 3 0.0009 0.0023 0.0091
Trypanosoma cruzi protein phosphatase 2C-like, putative 0.0014 0.0053 0.0756
Brugia malayi RNA binding protein 0.0046 0.0239 0.1292
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-gamma catalytic subunit 0.0021 0.0092 0.0368
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0066 0.0951
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0025 0.0121
Schistosoma mansoni nuclear hormone receptor 0.001 0.0025 0.0121
Brugia malayi beta-lactamase family protein 0.0048 0.0254 0.1373
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0018 0.0075 0.1084
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0025 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0089 0.048
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0017 0.0066 0.0951
Schistosoma mansoni tar DNA-binding protein 0.0046 0.0239 0.117
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0064 0.0352 0.1899
Trypanosoma brucei unspecified product 0.0007 0.001 0.0146
Entamoeba histolytica serine/threonine protein phosphatase PP1-2, putative 0.0014 0.0053 0.0757
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Onchocerca volvulus 0.0023 0.0103 0.1483
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0047 0.0251 0.3605
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0254 0.3658
Echinococcus granulosus transcription factor Dp 1 0.0027 0.0131 0.0642
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0033 0.0165 0.0663
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0083 0.045
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0017 0.0066 0.0951
Trichomonas vaginalis ap endonuclease, putative 0.0012 0.0036 0.0525
Leishmania major serine/threonine protein phosphatase 2A regulatory subunit, putative 0.001 0.0027 0.039
Trypanosoma cruzi protein phosphatase 2A regulatory subunit, putative 0.0122 0.0695 1
Echinococcus granulosus Protein patched homolog 1 0.0026 0.0123 0.06
Loa Loa (eye worm) DR-78 0.001 0.0025 0.0099
Toxoplasma gondii isocitrate dehydrogenase 0.001 0.0025 0.0923
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.009 0.1298
Trichomonas vaginalis protein phosphatase-1, putative 0.0028 0.0132 0.1903
Loa Loa (eye worm) hypothetical protein 0.0026 0.0123 0.0492
Trichomonas vaginalis D-aminoacylase, putative 0.0048 0.0254 0.3658
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.0143
Giardia lamblia Rab geranylgeranyltransferase 0.0017 0.0066 0.0951
Schistosoma mansoni hypothetical protein 0.0348 0.2044 1
Onchocerca volvulus 0.0022 0.01 0.1435
Brugia malayi Ser/Thr protein phosphatase family protein 0.002 0.0086 0.0464
Trypanosoma cruzi cytochrome P450, putative 0.001 0.0026 0.0368
Trypanosoma brucei serine threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.002 0.0089 0.0075
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0018 0.0075 1
Leishmania major cytochrome p450-like protein 0.001 0.0026 0.0368
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0008 0.0015 0.0506
Brugia malayi CHE-14 protein 0.0026 0.0123 0.0663
Schistosoma mansoni single-minded 0.003 0.0146 0.0715
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0038 0.0553
Echinococcus granulosus lamin dm0 0.0036 0.0182 0.0891
Brugia malayi hypothetical protein 0.0023 0.0103 0.0557
Trichomonas vaginalis guanylate cyclase, putative 0.0008 0.0014 0.0199
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0075 0.1084
Trichomonas vaginalis DNA helicase recq, putative 0.0007 0.0009 0.0133
Echinococcus granulosus aryl hydrocarbon receptor 0.0008 0.0014 0.0068
Toxoplasma gondii protein phosphatase 2C domain-containing protein 0.0014 0.0053 0.1999
Echinococcus granulosus mitogen activated protein kinase 0.0031 0.0155 0.0757
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.001 0.0025 0.0026
Mycobacterium ulcerans beta-lactamase 0.0048 0.0254 0.0229
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0126
Trichomonas vaginalis protein phosphatase-5, putative 0.0021 0.0092 0.132
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Loa Loa (eye worm) hypothetical protein 0.0008 0.0014 0.0055
Trypanosoma cruzi serine/threonine protein phosphatase type 5, putative 0.0048 0.0253 0.3648
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0025 0.0025
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0031 0.0155 0.062
Echinococcus multilocularis protein phosphatase 1b 0.0097 0.0543 0.0549
Trypanosoma cruzi serine/threonine protein phosphatase 2A regulatory subunit, putative 0.0007 0.0006 0.0089
Brugia malayi Protein phosphatase 2C containing protein 0.011 0.0627 0.3386
Loa Loa (eye worm) serine/threonine protein phosphatase PP1 isozyme 1 0.0021 0.0092 0.0368
Onchocerca volvulus 0.003 0.0149 0.2147
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.1019
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0014 0.0199
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0089 0.048
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Trypanosoma cruzi protein phosphatase 2C, putative 0.0014 0.0053 0.0756
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0007 0.0009 0.0009
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0022 0.01 0.0101
Trichomonas vaginalis serine/threonine protein phosphatase 2A regulatory subunit A, putative 0.0007 0.0006 0.0089
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0033 0.0165 0.238
Entamoeba histolytica HEAT repeat domain containing protein 0.0008 0.0014 0.0208
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0126
Giardia lamblia Ser/Thr phosphatase 2C, putative 0.0014 0.0053 0.0756
Echinococcus multilocularis protein patched 0.0026 0.0123 0.0124
Loa Loa (eye worm) transcription factor SMAD2 0.0074 0.0406 0.1629
Brugia malayi intermediate filament protein 0.0036 0.0182 0.0984
Echinococcus granulosus netrin receptor unc 5 0.0009 0.002 0.0099
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0031 0.0155 0.2226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0056 0.0812
Brugia malayi Death domain containing protein 0.0009 0.002 0.0109
Brugia malayi isocitrate dehydrogenase 0.001 0.0025 0.0137
Leishmania major serine/threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0017 0.0066 0.0067
Echinococcus granulosus beta LACTamase domain containing family member 0.0048 0.0254 0.1243
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0025 0.0133
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0025 0.0121
Leishmania major ATP-dependent phosphofructokinase 0.0067 0.0367 0.5281
Trypanosoma brucei protein phosphatase 2C, putative 0.0014 0.0053 0.0756
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0012 0.0036 0.0525
Echinococcus multilocularis aryl hydrocarbon receptor 0.0008 0.0014 0.0014
Mycobacterium tuberculosis Conserved protein 0.0048 0.0254 0.0229
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0089 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trypanosoma brucei protein phosphatase 1, putative 0.0033 0.0165 0.238
Giardia lamblia Protein phosphatase PP2A regulatory subunit B 0.0122 0.0695 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0007 0.0009 0.0133
Giardia lamblia Ser/Thr phosphatase 2A, 65kDa reg sub A 0.0011 0.0035 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Loa Loa (eye worm) protein phosphatase PP2A regulatory subunit 0.0011 0.0035 0.0142
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0025 0.0121
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta 0.0033 0.0165 0.0809
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0031 0.0155 0.2226
Onchocerca volvulus 0.0048 0.0254 0.3658
Plasmodium vivax 6-phosphofructokinase, putative 0.0018 0.0075 0.2021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.009 0.1298
Echinococcus granulosus histone acetyltransferase KAT2B 0.0087 0.0485 0.2374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.009 0.1298
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0009 0.0023 0.0111
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Brugia malayi Niemann-Pick C1 protein precursor 0.0061 0.0329 0.1779
Trichomonas vaginalis ap endonuclease, putative 0.0012 0.0036 0.0525
Trypanosoma cruzi PAB1-binding protein , putative 0.0016 0.006 0.0864
Brugia malayi Uncoordinated protein 44 0.0009 0.002 0.0109
Plasmodium falciparum histone acetyltransferase GCN5 0.0024 0.0111 0.3064
Mycobacterium ulcerans arylsulfatase AtsD 0.0011 0.0036 0.001
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0012 0.0036 0.0525
Echinococcus granulosus protein phosphatase 1b 0.0097 0.0543 0.2658
Schistosoma mansoni protein phosphatase 2C 0.0097 0.0543 0.2658
Plasmodium vivax serine/threonine protein phosphatase 5, putative 0.0046 0.0239 0.681
Trypanosoma cruzi DNA polymerase kappa, putative 0.003 0.0144 0.2065
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.001 0.0025 0.0026
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0089 0.0435
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.1019
Plasmodium vivax ataxin-2 like protein, putative 0.0016 0.006 0.1574
Brugia malayi Sulfatase family protein 0.0011 0.0036 0.0193
Loa Loa (eye worm) hypothetical protein 0.0064 0.0348 0.1396
Mycobacterium ulcerans hypothetical protein 0.0048 0.0254 0.0229
Brugia malayi exodeoxyribonuclease III family protein 0.0012 0.0036 0.0197
Brugia malayi Serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0021 0.0092 0.0496
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0089 0.0435
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.0143
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0048 0.0254 0.1019
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0089 0.05 0.2447
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0025 0.0133
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0046 0.0659
Trichomonas vaginalis DNA helicase recq1, putative 0.0013 0.0046 0.0659
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0089 0.048
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0075 0.1084
Brugia malayi Cytochrome P450 family protein 0.001 0.0026 0.0138
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0089 0.048
Schistosoma mansoni aryl hydrocarbon receptor 0.003 0.0146 0.0715
Entamoeba histolytica phosphofructokinase, putative 0.0067 0.0367 0.5281
Loa Loa (eye worm) serine/threonine protein phosphatase 5 0.0046 0.0239 0.0959
Schistosoma mansoni tar DNA-binding protein 0.0046 0.0239 0.117
Trypanosoma cruzi PAB1-binding protein , putative 0.0016 0.006 0.0864
Echinococcus granulosus bloom syndrome protein 0.0013 0.0046 0.0224
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0012 0.0036 0.0525
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Schistosoma mansoni hypothetical protein 0.0007 0.0009 0.0044
Mycobacterium leprae Isocitrate lyase 0.0788 0.467 0.4663
Loa Loa (eye worm) serine/threonine-protein phosphatase PP1-beta 0.0014 0.0053 0.0211
Echinococcus granulosus histone acetyltransferase KAT2B 0.0026 0.0124 0.0607
Echinococcus granulosus Serine:threonine protein phosphatase 2A 65 kDa 0.0007 0.0006 0.003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0083 0.0084
Loa Loa (eye worm) hypothetical protein 0.0028 0.0135 0.0543
Schistosoma mansoni 6-phosphofructokinase 0.0067 0.0367 0.1795
Schistosoma mansoni hypothetical protein 0.0019 0.0083 0.0408
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0036 0.0182 0.073
Brugia malayi hypothetical protein 0.001 0.0027 0.0147
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0089 0.0435
Brugia malayi bHLH-PAS transcription factor 0.0022 0.01 0.0539
Giardia lamblia Hypothetical protein 0.0011 0.0036 0.0514
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0089 0.048
Mycobacterium tuberculosis Probable lipase LipE 0.0048 0.0254 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0065 0.0934
Loa Loa (eye worm) hypothetical protein 0.0016 0.006 0.0241
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0012 0.0036 0.0525
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0089 0.009
Mycobacterium leprae Probable lipase LipE 0.0048 0.0254 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0089 0.0356
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0017 0.0066 0.0357
Echinococcus multilocularis Serine:threonine protein phosphatase 2A 65 kDa 0.0011 0.0035 0.0036
Echinococcus granulosus Niemann Pick C1 protein 0.0087 0.0485 0.2371
Echinococcus granulosus geminin 0.0348 0.2044 1
Leishmania major DNA polymerase eta, putative 0.001 0.0029 0.0423
Giardia lamblia GTOR 0.0028 0.0133 0.1908
Loa Loa (eye worm) hypothetical protein 0.0021 0.0092 0.0368
Schistosoma mansoni protein phosphatase-7 0.002 0.0086 0.042
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0023 0.0103 0.1484
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0023 0.0327
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0064 0.0348 0.5012
Brugia malayi serine/threonine protein phosphatase 5 0.0046 0.0239 0.1292
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0038 0.0553
Onchocerca volvulus 0.001 0.0025 0.0355
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0089 0.0435
Trypanosoma cruzi serine/threonine-protein phosphatase PP1, putative 0.0021 0.0092 0.132
Trypanosoma cruzi serine/threonine-protein phosphatase PP1 alpha 0.0021 0.0092 0.132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.1421
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0028 0.0133 0.1908
Schistosoma mansoni protein phosphatase-1 0.0021 0.0092 0.0449
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0008 0.0014 0.0055
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0064 0.0348 0.1704
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0089 0.0435
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0089 0.009
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.001 0.0029 0.003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0083 0.0408
Schistosoma mansoni thyroid hormone receptor 0.002 0.0089 0.0435
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0089 0.0356
Trichomonas vaginalis phosphofructokinase, putative 0.0018 0.0075 0.1084
Echinococcus multilocularis lamin 0.0036 0.0182 0.0184
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0026 0.0124 0.1785
Echinococcus granulosus jun protein 0.0029 0.014 0.0686
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.001 0.0025 0.0366
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0017 0.0066 0.0951
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0101 0.1449
Brugia malayi 6-phosphofructokinase 0.0067 0.0367 0.1982
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0031 0.0155 0.6052
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.0155 0.2226
Trichomonas vaginalis protein phosphatase PP2A regulatory subunit B, putative 0.0122 0.0695 1
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0006 0.0089
Echinococcus granulosus protein phosphatase 1b 0.011 0.0627 0.3066
Echinococcus multilocularis musashi 0.0036 0.0182 0.0184
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0144 0.2065
Brugia malayi hypothetical protein 0.0016 0.006 0.0324
Echinococcus granulosus mitogen activated protein kinase 3 0.0031 0.0155 0.0757
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Schistosoma mansoni tar DNA-binding protein 0.0046 0.0239 0.117
Mycobacterium ulcerans isocitrate lyase AceAb 0.1681 1 1
Entamoeba histolytica protein phosphatase regulatory subunit, putative 0.0122 0.0695 1
Loa Loa (eye worm) acetyltransferase 0.0089 0.05 0.2005
Toxoplasma gondii isocitrate dehydrogenase 0.001 0.0025 0.0923
Echinococcus granulosus sterol regulatory element binding protein 0.0026 0.0123 0.06
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0356
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0017 0.0071 0.0347
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0089 0.0435
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.001 0.0025 0.0124
Trypanosoma cruzi cytochrome P450, putative 0.001 0.0026 0.0368
Brugia malayi Nuclear hormone receptor E75 0.001 0.0025 0.0133
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0064 0.0348 0.5012
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0031 0.0155 0.2226
Schistosoma mansoni protein phosphatase 2c gamma 0.0014 0.0053 0.0257
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0029 0.014 0.0141
Giardia lamblia DINP protein human, muc B family 0.0015 0.0058 0.0831
Loa Loa (eye worm) RNA binding protein 0.0046 0.0239 0.0958
Toxoplasma gondii target of rapamycin (TOR), putative 0.0021 0.009 0.3495
Schistosoma mansoni nuclear receptor 0.001 0.0025 0.0121
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0031 0.0155 0.2226
Trichomonas vaginalis protein phosphatase type 2C, putative 0.0014 0.0053 0.0756
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0032 0.0154
Schistosoma mansoni protein phosphatase pp2a regulatory subunit B 0.0122 0.0695 0.3399
Brugia malayi ImpB/MucB/SamB family protein 0.001 0.0029 0.0159
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0067 0.0367 0.0354
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0083 0.0334
Schistosoma mansoni protein phosphatase 2C 0.0014 0.0053 0.0257
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0133 0.1908
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0008 0.0014 0.0199
Brugia malayi nuclear hormone receptor 0.002 0.0089 0.048
Echinococcus granulosus dna polymerase kappa 0.003 0.0144 0.0702
Trichomonas vaginalis D-aminoacylase, putative 0.0048 0.0254 0.3658
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0009 0.0023 0.0123
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0008 0.0016 0.0223
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0089 0.1278
Brugia malayi beta-lactamase family protein 0.0048 0.0254 0.1373
Entamoeba histolytica hypothetical protein 0.0022 0.01 0.1433
Brugia malayi beta-lactamase 0.0048 0.0254 0.1373
Echinococcus multilocularis protein phosphatase 5 0.0046 0.0239 0.0241
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.002 0.0698
Schistosoma mansoni protein phosphatase 2C 0.011 0.0627 0.3066
Brugia malayi Protein kinase domain containing protein 0.0009 0.0022 0.0118
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0017 0.0066 0.0951
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0048 0.0254 0.0229
Schistosoma mansoni lamin 0.0036 0.0182 0.0891
Schistosoma mansoni hypothetical protein 0.0042 0.0218 0.1066
Schistosoma mansoni hypothetical protein 0.0019 0.0083 0.0408
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0017 0.0066 0.0067
Trypanosoma brucei PAB1-binding protein , putative 0.0016 0.006 0.0864
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0099 0.1421
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0009 0.0023 0.0327
Schistosoma mansoni hypothetical protein 0.0064 0.0352 0.172
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.0033 0.0165 0.0809
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0254 0.0241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0089 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0017 0.0066 0.0951
Plasmodium falciparum serine/threonine protein phosphatase 5 0.0046 0.0239 0.681
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0033 0.0165 0.238
Schistosoma mansoni protein phosphatase-1 0.0033 0.0165 0.0809
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0011 0.0036 0.0514
Entamoeba histolytica protein phosphatase, putative 0.0014 0.0053 0.0756
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.1019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0089 0.009
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.001 0.0025 0.0563
Mycobacterium ulcerans arylsulfatase, AslA 0.0011 0.0036 0.001
Leishmania major protein phosphatase 2C, putative 0.0014 0.0053 0.0756
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0047 0.0251 0.1226
Onchocerca volvulus 0.0064 0.0352 0.5059
Leishmania major serine/threonine protein phosphatase pp1(5.9), putative 0.0021 0.0092 0.132
Brugia malayi nuclear receptor NHR-88 0.002 0.0089 0.048
Schistosoma mansoni tar DNA-binding protein 0.0046 0.0239 0.117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0078 0.1125
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0022 0.01 0.0487
Trypanosoma brucei protein phosphatase 2C, putative 0.0014 0.0053 0.0756
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0012 0.0036 0.0146
Brugia malayi Inositol-1 0.0023 0.0103 0.0557
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0007 0.0009 0.0133
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0007 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0006 0.0001 0.0004
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0017 0.0066 0.0951
Brugia malayi nuclear receptor NHR-88 0.001 0.0025 0.0133
Trichomonas vaginalis protein phosphatase-5, putative 0.0028 0.0132 0.1903
Trichomonas vaginalis protein phosphatase 2A, caeel, putative 0.0014 0.0053 0.0757
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0047 0.0251 0.1226
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0047 0.0251 0.3605
Trypanosoma cruzi target of rapamycin kinase 3 0.0022 0.0099 0.1423
Brugia malayi nuclear receptor RXR 0.001 0.0025 0.0133
Schistosoma mansoni protein phosphatase type 1 0.0021 0.0092 0.0449
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0216 0.1256 0.5034
Loa Loa (eye worm) hypothetical protein 0.002 0.0089 0.0356
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0108 0.156
Echinococcus granulosus inositol monophosphatase 1 0.0023 0.0103 0.0504
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0025 0.0121
Loa Loa (eye worm) hypothetical protein 0.0019 0.0083 0.0334
Toxoplasma gondii hypothetical protein 0.0047 0.025 0.9816
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0009 0.0023 0.0327
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0089 0.0435
Entamoeba histolytica hypothetical protein 0.0022 0.01 0.1433
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0017 0.0066 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0036 0.0514
Brugia malayi protein phosphatase PP2A regulatory subunit 0.0011 0.0035 0.0191
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0009 0.002 0.0416
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0099
Leishmania major phosphatidylinositol 3-kinase, putative 0.0009 0.0023 0.0327
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0089 0.0435
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0089 0.1278
Trichomonas vaginalis protein phosphatase-1, putative 0.0033 0.0165 0.238
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0089 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0014 0.0199
Echinococcus granulosus Serine:threonine protein phosphatase 2A 65 kDa 0.0011 0.0035 0.0173
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0033 0.0165 0.0167
Brugia malayi MH2 domain containing protein 0.0074 0.0406 0.2195
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0089 0.048
Loa Loa (eye worm) beta-lactamase 0.0048 0.0254 0.1019
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.0254 0.3658
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0216 0.1256 0.1268
Brugia malayi Nuclear hormone receptor E75 0.001 0.0025 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0089 0.048
Trypanosoma brucei unspecified product 0.0025 0.0115 0.1658
Loa Loa (eye worm) TAR-binding protein 0.0046 0.0239 0.0958
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0021 0.0092 0.132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0044 0.0628
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0028 0.0133 0.0134
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0017 0.0066 0.1752
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0033 0.0165 0.238
Loa Loa (eye worm) hypothetical protein 0.0042 0.0218 0.0874
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.0033 0.0165 0.0167
Brugia malayi nuclear receptor RXR 0.0011 0.0032 0.017
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0064 0.0348 0.1704

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Agonist activity at melatonin receptor in Xenopus laevis melanophores assessed as effect on pigment granule distribution at 100 uM ChEMBL. 17988084
Log IC50 (functional) = 4.81 Antagonist activity at melatonin receptor in Xenopus laevis melanophores assessed as reduction of melatonin-induced pigment aggregation ChEMBL. 17988084

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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