Detailed information for compound 457521

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 274.315 | Formula: C15H18N2O3
  • H donors: 3 H acceptors: 2 LogP: -0.07 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC1NC(C(=O)O)c2c(C1)c1cc(OC)ccc1[nH]2
  • InChi: 1S/C15H18N2O3/c1-3-8-6-11-10-7-9(20-2)4-5-12(10)17-13(11)14(16-8)15(18)19/h4-5,7-8,14,16-17H,3,6H2,1-2H3,(H,18,19)
  • InChiKey: XYWKVJOWOSIIEX-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0047 0.0047
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0039 0.0152 0.0226
Loa Loa (eye worm) hypothetical protein 0.0963 0.6379 1
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0158 0.0489
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0067 0.0292
Schistosoma mansoni organic anion transporter 0.0123 0.0719 0.0716
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0152 0.0233
Brugia malayi hypothetical protein 0.0043 0.0184 0.0281
Onchocerca volvulus 0.0018 0.0015 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Brugia malayi hypothetical protein 0.0123 0.0719 0.1121
Leishmania major cathepsin L-like protease 0.007 0.0364 0.1781
Brugia malayi jmjC domain containing protein 0.0034 0.012 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0015 0.0036
Onchocerca volvulus 0.0123 0.0719 0.1107
Schistosoma mansoni agrin 0.0084 0.0456 0.0453
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Echinococcus multilocularis pol protein 0.1072 0.7117 0.7117
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0022 0.0056
Mycobacterium tuberculosis Conserved hypothetical protein 0.0165 0.1006 0.3385
Echinococcus granulosus lysine specific demethylase 6a 0.0034 0.012 0.012
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0084 0.0456 0.0709
Schistosoma mansoni tar DNA-binding protein 0.007 0.0361 0.0358
Onchocerca volvulus 0.004 0.0158 0.0226
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Trypanosoma brucei metacaspase MCA3 0.0019 0.0022 0.0069
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0165 0.0395
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0039 0.0152 0.0233
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0022 0.0069
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0204 0.1265 0.3961
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0158 0.0158
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0047 0.0113
Plasmodium vivax hypothetical protein, conserved 0.004 0.0158 0.1144
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.1217 0.2916
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Entamoeba histolytica hypothetical protein 0.004 0.0158 0.0344
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0165 0.0395
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0158 0.0379
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0122 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0039 0.0152 0.0233
Onchocerca volvulus 0.0963 0.6379 1
Loa Loa (eye worm) TAR-binding protein 0.007 0.0361 0.0554
Brugia malayi hypothetical protein 0.0043 0.0184 0.0281
Loa Loa (eye worm) hypothetical protein 0.0261 0.1647 0.2571
Echinococcus multilocularis lysine specific demethylase 5A 0.0128 0.0752 0.0752
Schistosoma mansoni jumonji/arid domain-containing protein 0.0131 0.0776 0.0773
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.023 0.023
Schistosoma mansoni lipoxygenase 0.0191 0.1176 0.1173
Schistosoma mansoni retinoic acid receptor RXR 0.0147 0.0884 0.0881
Onchocerca volvulus Bile acid receptor homolog 0.0039 0.0152 0.0217
Entamoeba histolytica P-glycoprotein-5 0.0023 0.0047 0.0078
Echinococcus granulosus RUN 0.0043 0.0184 0.0184
Echinococcus multilocularis pol protein 0.1072 0.7117 0.7117
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.0014 0.0009
Onchocerca volvulus 0.0018 0.0015 0.0001
Onchocerca volvulus 0.004 0.0158 0.0226
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0152 0.0152
Echinococcus multilocularis mitogen activated protein kinase 3 0.0111 0.0637 0.0637
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0023 0.0047 0.0061
Entamoeba histolytica NAD synthetase, putative 0.009 0.0501 0.1168
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0122 0.0118
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0158 0.0158
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0067 0.0292
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0039 0.0152 0.0226
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0111 0.0637 0.0987
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0134 0.0791 0.0788
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0047 0.0047
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.031 0.1982 0.6729
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0022 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1149 0.2754
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0158 0.0749
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Trypanosoma cruzi NAD+ synthase, putative 0.009 0.0501 0.2463
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.012 0.0176
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.023 0.0227
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0111 0.0637 0.3146
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0188 0.09
Brugia malayi hypothetical protein 0.004 0.0158 0.0241
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0047 0.0113
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0165 0.0395
Onchocerca volvulus 0.0123 0.0719 0.1107
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0029 0.0029
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0158 0.0158
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.009 0.0501 0.12
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0047 0.0047
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.1647 0.1647
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0032
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0364 0.1781
Echinococcus multilocularis muscleblind protein 0.0325 0.2079 0.2079
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0637 0.1527
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0015 0.0001
Trichomonas vaginalis taga, putative 0.0023 0.0047 0.0113
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0067 0.0199
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4172 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.012 0.0561
Loa Loa (eye worm) hypothetical protein 0.0034 0.012 0.0176
Brugia malayi jmjC domain containing protein 0.0131 0.0776 0.1211
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0015 0.0015
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0034
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0015 0.0011
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0017
Echinococcus multilocularis agrin 0.0084 0.0456 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0022 0.0053
Brugia malayi hypothetical protein 0.0028 0.0078 0.0116
Loa Loa (eye worm) hypothetical protein 0.0034 0.0122 0.0178
Mycobacterium ulcerans glutaminase 0.0301 0.1921 0.6519
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0018 0.0014 0.0011
Brugia malayi jmjC domain containing protein 0.0128 0.0752 0.1173
Echinococcus multilocularis jumonji domain containing 1A 0.0034 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0043 0.0184 0.0275
Schistosoma mansoni multidrug resistance protein 0.0023 0.0047 0.0044
Schistosoma mansoni lipoxygenase 0.0113 0.0649 0.0646
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0152 0.0233
Echinococcus granulosus apoptotic protease activating factor 1 0.0045 0.0197 0.0197
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0022
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0123 0.0719 0.0719
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0047 0.0078
Leishmania major cathepsin L-like protease 0.007 0.0364 0.1781
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0029 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0015 0.0036
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0022 0.0028
Loa Loa (eye worm) hypothetical protein 0.0036 0.0135 0.0198
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0017
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0054 0.0257 0.0253
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0034
Brugia malayi beta-lactamase 0.004 0.0158 0.0241
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0078 0.0503
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0039 0.0152 0.0226
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0022 0.0019
Echinococcus granulosus ecdysone induced protein 78C 0.0039 0.0152 0.0152
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0047 0.0113
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0022 0.0056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0235
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0158 0.0155
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0036 0.0135 0.0631
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0047 0.0113
Loa Loa (eye worm) steroid hormone receptor 0.0039 0.0152 0.0226
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0036 0.0135 0.0631
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0014 0.0011
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0165 0.0165
Loa Loa (eye worm) glutaminase 0.0301 0.1921 0.3001
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0084 0.0456 0.0709
Onchocerca volvulus 0.0062 0.0311 0.0467
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.015 0.071
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.009 0.0501 0.3885
Brugia malayi hypothetical protein 0.0021 0.0029 0.0039
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0311 0.0476
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.023 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Schistosoma mansoni nuclear receptor nhr-48 0.0018 0.0014 0.0011
Brugia malayi Cell death protein 3 precursor 0.0065 0.0328 0.0508
Echinococcus granulosus agrin 0.0084 0.0456 0.0456
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0184 0.0184
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0456 0.3529
Echinococcus granulosus cpg binding protein 0.0066 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0026 0.0067 0.0092
Leishmania major p-glycoprotein 0.0023 0.0047 0.0195
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0165 0.0784
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0047 0.0113
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.015 0.0462
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0184 0.0184
Brugia malayi jmjC domain containing protein 0.0034 0.012 0.0182
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.1445 0.2255
Plasmodium falciparum metacaspase-like protein 0.0019 0.0022 0.0024
Loa Loa (eye worm) nuclear hormone receptor 0.0018 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0123 0.0719 0.1115
Brugia malayi jmjC domain containing protein 0.0034 0.012 0.0182
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1149 0.2754
Schistosoma mansoni hypothetical protein 0.0889 0.5883 0.5881
Brugia malayi TAR-binding protein 0.007 0.0361 0.056
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0637 0.0634
Loa Loa (eye worm) hypothetical protein 0.0084 0.0456 0.0703
Echinococcus multilocularis mitogen activated protein kinase 0.0111 0.0637 0.0637
Brugia malayi Doublecortin family protein 0.0043 0.0184 0.0281
Mycobacterium tuberculosis Conserved protein 0.004 0.0158 0.0489
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0152 0.0233
Echinococcus multilocularis muscleblind protein 1 0.0325 0.2079 0.2079
Brugia malayi sodium-independent organic anion transporter family protein 0.0123 0.0719 0.1121
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0637 0.1527
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Trypanosoma brucei metacaspase MCA2 0.0019 0.0022 0.0069
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0039 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.0187 0.1149 0.1146
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0226
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0023 0.0047 0.011
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0892 0.4423
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Onchocerca volvulus Putative organic anion transporter 0.0123 0.0719 0.1107
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0047 0.0113
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0047 0.0113
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.0144 0.0144
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0022 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0067 0.0199
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0253 0.1226
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0152 0.0233
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0152 0.0149
Toxoplasma gondii transporter, major facilitator family protein 0.0123 0.0719 0.5632
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0047 0.0113
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0047 0.0113
Brugia malayi ecdysteroid receptor 0.0039 0.0152 0.0233
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0014 0.0014
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0047 0.0047
Mycobacterium ulcerans hypothetical protein 0.0026 0.0067 0.0199
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0122 0.0118
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0032
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0023 0.0047 0.0258
Loa Loa (eye worm) ctsf protein 0.0018 0.0015 0.0011
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0014 0.0011
Echinococcus granulosus caspase 2 0.0065 0.0328 0.0328
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0067 0.0177
Brugia malayi hypothetical protein 0.0963 0.6379 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0111 0.0637 0.0637
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0453 0.2942 1
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0022 0.0069
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0637 0.1527
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0113 0.0651 0.0651
Leishmania major hypothetical protein, conserved 0.0034 0.012 0.0561
Onchocerca volvulus 0.0262 0.166 0.2585
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0651 0.0648
Loa Loa (eye worm) hypothetical protein 0.0026 0.0067 0.0092
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0039 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0123 0.0719 0.1115
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0123 0.0719 0.1115
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.023 0.0355
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0158 0.0749
Loa Loa (eye worm) cysteine protease 0.0018 0.0015 0.0011
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0158 0.0379
Echinococcus granulosus jumonji domain containing 1A 0.0034 0.012 0.012
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0046 0.0046
Trypanosoma cruzi NAD+ synthase, putative 0.009 0.0501 0.2463
Mycobacterium ulcerans beta-lactamase 0.004 0.0158 0.051
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0029 0.0039
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0015 0.0034
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0127 0.0746 0.0746
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0014 0.0014
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.031 0.1982 0.6722
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0015 0.0015
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0188 0.09
Loa Loa (eye worm) hypothetical protein 0.0034 0.012 0.0176
Onchocerca volvulus 0.0018 0.0015 0.0001
Brugia malayi steroid hormone receptor 0.0039 0.0152 0.0233
Mycobacterium ulcerans lipase LipD 0.004 0.0158 0.051
Brugia malayi photoreceptor-specific nuclear receptor 0.0039 0.0152 0.0233
Loa Loa (eye worm) runx1 0.0121 0.0705 0.1093
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0034 0.012 0.0844
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1808 0.4334
Trypanosoma cruzi metacaspase, putative 0.0019 0.0022 0.0069
Trichomonas vaginalis abcb9, putative 0.0023 0.0047 0.0113
Loa Loa (eye worm) hypothetical protein 0.0123 0.0719 0.1115
Brugia malayi nuclear receptor RXR 0.0021 0.0029 0.0039
Loa Loa (eye worm) fibroinase 0.0018 0.0015 0.0011
Onchocerca volvulus 0.0123 0.0719 0.1107
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0398 0.0395
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0047 0.0113
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0165 0.0165
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0285 0.1808 0.2825
Loa Loa (eye worm) hypothetical protein 0.0123 0.0719 0.1115
Mycobacterium ulcerans hypothetical protein 0.004 0.0158 0.051
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1808 0.4334
Loa Loa (eye worm) agrin synaptic family protein 0.0084 0.0456 0.0703
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.009 0.0501 0.3885
Echinococcus granulosus cathepsin l1 0.0018 0.0015 0.0015
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0158 0.0241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0039 0.0152 0.0226
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0039 0.0152 0.0233
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.009 0.0501 0.1659
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0111 0.0637 0.4978
Brugia malayi GMP synthase 0.0036 0.0135 0.0204
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0456 0.3529
Onchocerca volvulus Cell death protein 3 homolog 0.0065 0.0328 0.0493
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0047 0.0113
Brugia malayi Steroid receptor seven-up type 2 0.0039 0.0152 0.0233
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0022 0.0058
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Brugia malayi orphan nuclear receptor NR2E1 0.0018 0.0014 0.0016
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.0014 0.0014
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0047 0.0047
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0136 0.0242
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4172 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0184 0.0275
Schistosoma mansoni hypothetical protein 0.0045 0.0197 0.0193
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0015 0.0017
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0047 0.0113
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0047 0.0047
Echinococcus granulosus FTZ F1 alpha 0.0039 0.0152 0.0152
Mycobacterium leprae Probable lipase LipE 0.004 0.0158 0.0318
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0014 0.0016
Echinococcus multilocularis JmjC domain containing protein 4 0.0034 0.012 0.012
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.0014 0.0014
Plasmodium vivax metacaspase 1, putative 0.0019 0.0022 0.0056
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0122 0.0122
Echinococcus multilocularis apoptotic protease activating factor 1 0.0045 0.0197 0.0197
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0039 0.0152 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0111 0.0637 0.3146
Brugia malayi hypothetical protein 0.0045 0.0197 0.0302
Schistosoma mansoni tar DNA-binding protein 0.007 0.0361 0.0358
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0165 0.12
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0067 0.0199
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0226
Loa Loa (eye worm) hypothetical protein 0.0123 0.0719 0.1115
Schistosoma mansoni tar DNA-binding protein 0.007 0.0361 0.0358
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0123 0.0719 0.0719
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0047 0.0113
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0067 0.0292
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.031 0.1982 0.6663
Schistosoma mansoni GMP synthetase 0.0036 0.0135 0.0131
Brugia malayi beta-lactamase family protein 0.004 0.0158 0.0241
Schistosoma mansoni organic anion transporter 0.0123 0.0719 0.0716
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0113 0.0651 0.0651
Schistosoma mansoni cpg binding protein 0.0066 0.0335 0.0332
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.015 0.036
Schistosoma mansoni rab6-interacting 0.0043 0.0184 0.018
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0023 0.0047 0.0086
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0128 0.0752 0.0752
Schistosoma mansoni inositol monophosphatase 0.0041 0.0165 0.0162
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0027 0.0036
Loa Loa (eye worm) hypothetical protein 0.0084 0.0456 0.0703
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0892 0.4423
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4172 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0039 0.0152 0.0152
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0015 0.0012
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0047 0.0113
Schistosoma mansoni polycystin 1-related 0.0043 0.0184 0.018
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0047 0.0113
Echinococcus multilocularis follistatin 0.0084 0.0456 0.0456
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0067 0.0177
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0018 0.0014 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0067 0.0098
Brugia malayi beta-lactamase family protein 0.004 0.0158 0.0241
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0235
Onchocerca volvulus 0.0034 0.0122 0.0169
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.0144 0.0144
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0453 0.2942 1
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0034
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0039 0.0152 0.0217
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0015 0.0001
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0204 0.1265 0.4283
Onchocerca volvulus 0.0018 0.0015 0.0001
Loa Loa (eye worm) hypothetical protein 0.0123 0.0719 0.1115
Brugia malayi MH2 domain containing protein 0.0128 0.0753 0.1175
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.009 0.0501 0.1509
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0635 0.4172 1
Echinococcus granulosus dnaJ subfamily B 0.0889 0.5883 0.5883
Brugia malayi SPARC precursor 0.0084 0.0456 0.0709
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.023 0.023
Plasmodium falciparum enoyl-acyl carrier reductase 0.0204 0.1265 0.427
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0047 0.0047
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0034 0.012 0.0561
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1808 0.4334
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Mycobacterium leprae conserved hypothetical protein 0.004 0.0158 0.0318
Schistosoma mansoni rab6-interacting 0.0043 0.0184 0.018
Echinococcus granulosus tar DNA binding protein 0.007 0.0361 0.0361
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0147 0.0884 0.0884
Echinococcus granulosus lysine specific demethylase 5A 0.0131 0.0776 0.0776
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0122 0.0118
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0122 0.0122
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1149 0.2754
Loa Loa (eye worm) jmjC domain-containing protein 0.0131 0.0776 0.1205
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0398 0.0395
Onchocerca volvulus Protein ultraspiracle homolog 0.0039 0.0152 0.0217
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0361 0.056
Loa Loa (eye worm) glutaminase 2 0.0301 0.1921 0.3001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0197 0.1217 0.2916
Brugia malayi Pre-SET motif family protein 0.0231 0.1445 0.226
Loa Loa (eye worm) hypothetical protein 0.0084 0.0456 0.0703
Onchocerca volvulus 0.0043 0.0184 0.0266
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0158 0.0489
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.0014 0.0014
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0023 0.0047 0.0195
Leishmania major metacaspase, putative 0.0019 0.0022 0.0069
Trypanosoma cruzi metacaspase, putative 0.0019 0.0022 0.0069
Schistosoma mansoni zinc finger protein 0.0018 0.0014 0.0011
Echinococcus multilocularis Protein lozenge 0.0121 0.0705 0.0705
Trypanosoma cruzi MFS transporter, putative 0.0123 0.0719 0.3554
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0029 0.0039
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0047 0.0113
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0047 0.0047
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.0014 0.0014
Plasmodium vivax multidrug resistance protein 1, putative 0.0023 0.0047 0.0258
Mycobacterium tuberculosis Conserved protein 0.004 0.0158 0.0489
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.012 0.0176
Echinococcus granulosus transcription factor btf3 0.0039 0.015 0.015
Echinococcus multilocularis phd:f box containing protein 0.0034 0.012 0.012
Schistosoma mansoni jumonji domain containing protein 0.0128 0.0752 0.0749
Toxoplasma gondii melibiase subfamily protein 0.0113 0.0651 0.5091
Echinococcus granulosus muscleblind protein 0.0325 0.2079 0.2079
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Brugia malayi hypothetical protein 0.0261 0.1647 0.2576
Schistosoma mansoni RAR-like nuclear receptor 0.0039 0.0152 0.0149
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0165 0.0784
Echinococcus granulosus JmjC domain containing protein 4 0.0034 0.012 0.012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1149 0.2754
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0014 0.0014
Toxoplasma gondii NAC domain-containing protein 0.0039 0.015 0.1082
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.023 0.023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4172 1
Trichomonas vaginalis glutaminase, putative 0.0301 0.1921 0.4603
Toxoplasma gondii protease inhibitor PI2 0.0084 0.0456 0.3529
Entamoeba histolytica hypothetical protein 0.004 0.0158 0.0344
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0029 0.0026
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0651 0.0648
Brugia malayi nuclear hormone receptor family member nhr-6 0.0018 0.0014 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1808 0.4334
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.0892 0.4423
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0226
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.009 0.0501 0.1659
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0022 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0067 0.0199
Brugia malayi RNA binding protein 0.007 0.0361 0.056
Treponema pallidum fructose-bisphosphate aldolase 0.0635 0.4172 1
Onchocerca volvulus 0.0043 0.0184 0.0266
Onchocerca volvulus 0.0053 0.0249 0.0369
Schistosoma mansoni hypothetical protein 0.0043 0.0184 0.018
Trichomonas vaginalis set domain proteins, putative 0.0262 0.1659 0.3976
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0165 0.0534
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0184 0.0275
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0029 0.0029
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0364 0.1781
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0039 0.0152 0.0152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0039 0.0152 0.0226
Brugia malayi hypothetical protein 0.0018 0.0014 0.0016
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0204 0.1265 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0158 0.0489
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0165 0.0784
Brugia malayi jmjC domain containing protein 0.0034 0.012 0.0182
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4172 1
Loa Loa (eye worm) beta-lactamase 0.004 0.0158 0.0235
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Plasmodium vivax GMP synthetase, putative 0.0036 0.0135 0.0956
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Echinococcus granulosus phd:f box containing protein 0.0034 0.012 0.012
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0158 0.0489
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0651 0.0648
Leishmania major cathepsin L-like protease 0.007 0.0364 0.1781
Plasmodium falciparum metacaspase 1 0.0019 0.0022 0.0024
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0023 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0106 0.0608 0.0605
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Loa Loa (eye worm) hypothetical protein 0.0045 0.0197 0.0296
Echinococcus multilocularis geminin 0.0187 0.1149 0.1149
Brugia malayi nuclear hormone receptor 0.0039 0.0152 0.0233
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0184 0.0184
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0128 0.0752 0.0752
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1808 0.4334
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0047 0.0113
Schistosoma mansoni cpg binding protein 0.0062 0.0311 0.0308
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0226
Echinococcus multilocularis caspase 0.0019 0.0022 0.0022
Schistosoma mansoni jumonji domain containing protein 0.0034 0.012 0.0117
Brugia malayi nuclear receptor NHR-88 0.0018 0.0014 0.0016
Schistosoma mansoni caspase-7 (C14 family) 0.0065 0.0328 0.0325
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1149 0.2754
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0226
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0235
Onchocerca volvulus 0.0018 0.0015 0.0001
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0204 0.1265 0.4167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0158 0.0379
Loa Loa (eye worm) hypothetical protein 0.0034 0.012 0.0176
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0184 0.0576
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0067 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.015 0.036
Trypanosoma brucei Metacaspase-4 0.0019 0.0022 0.0069
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0456 0.3529
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0226
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0111 0.0637 0.3146
Echinococcus multilocularis cpg binding protein 0.0066 0.0335 0.0335
Echinococcus multilocularis cysteine protease 0.0018 0.0015 0.0015
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0019 0.0022 0.0022
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0204 0.1265 0.4256
Onchocerca volvulus 0.0084 0.0456 0.0694
Brugia malayi nuclear receptor RXR 0.0018 0.0014 0.0016
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0263 0.1274
Echinococcus multilocularis tar DNA binding protein 0.007 0.0361 0.0361
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1149 0.2754
Brugia malayi conserved hypotetical protein 0.0018 0.0014 0.0016
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0158 0.0489
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Brugia malayi nuclear receptor NHR-67 0.0018 0.0014 0.0016
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.015 0.071
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0453 0.2942 1
Echinococcus granulosus geminin 0.0187 0.1149 0.1149
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0023 0.0046 0.0046
Trypanosoma cruzi metacaspase, putative 0.0019 0.0022 0.0069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0067 0.0092
Schistosoma mansoni tar DNA-binding protein 0.007 0.0361 0.0358
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0165 0.0784
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.1599 0.5411
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0456 0.3529
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0032
Schistosoma mansoni hypothetical protein 0.0187 0.1149 0.1146
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0158 0.0489
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0158 0.0379
Schistosoma mansoni hypothetical protein 0.004 0.0158 0.0155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Schistosoma mansoni glutaminase 0.0301 0.1921 0.1918
Entamoeba histolytica P-glycoprotein-2 0.0023 0.0047 0.0078
Trypanosoma cruzi metacaspase, putative 0.0019 0.0022 0.0069
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0039 0.0152 0.0152
Entamoeba histolytica P-glycoprotein-2, putative 0.0023 0.0047 0.0078
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0226
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0637 0.3146
Schistosoma mansoni lozenge 0.0121 0.0705 0.0702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0325 0.2079 0.325
Entamoeba histolytica P-glycoprotein-1 0.0023 0.0047 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0039 0.0152 0.0226
Plasmodium falciparum JmjC domain-containing protein, putative 0.0034 0.012 0.036
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0061
Schistosoma mansoni microtubule-associated protein tau 0.15 1 1
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0047 0.0047
Echinococcus multilocularis multidrug resistance protein 1 0.0023 0.0047 0.0047
Trichomonas vaginalis abcb9, putative 0.0023 0.0047 0.0113
Toxoplasma gondii hypothetical protein 0.0051 0.0232 0.1737
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0453 0.2942 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0398 0.0611
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0152 0.0233
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0039 0.0152 0.0152
Entamoeba histolytica hypothetical protein 0.004 0.0158 0.0344
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Brugia malayi secreted modular calcium-binding protein 1 0.0084 0.0456 0.0709
Trichomonas vaginalis hypothetical protein 0.0204 0.1265 0.3031
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0204 0.1265 0.427
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.0753 0.1169
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0078 0.0503
Echinococcus multilocularis ecdysone induced protein 78C 0.0039 0.0152 0.0152
Brugia malayi Inositol-1 0.0041 0.0165 0.0252
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0158 0.0155
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0152 0.0152
Onchocerca volvulus 0.0023 0.0047 0.0052
Schistosoma mansoni follistatin 0.0084 0.0456 0.0453
Brugia malayi nuclear receptor NHR-88 0.0039 0.0152 0.0233
Echinococcus multilocularis caspase 8 0.0019 0.0022 0.0022
Brugia malayi sodium-independent organic anion transporter family protein 0.0123 0.0719 0.1121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4172 1
Echinococcus multilocularis transcription factor btf3 0.0039 0.015 0.015
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0111 0.0637 0.3146
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0635 0.4172 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0039 0.0152 0.0233
Echinococcus granulosus caspase 0.0019 0.0022 0.0022
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0014 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0152 0.0233
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0235
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0034 0.012 0.0117
Onchocerca volvulus 0.0123 0.0719 0.1107
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0047 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0078 0.0348
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0003 0.0003
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.1647 0.1647
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0028 0.0078 0.0109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0152 0.0233
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0061
Echinococcus granulosus nuclear factor of activated T cells 5 0.0081 0.0438 0.0438
Echinococcus multilocularis FTZ F1 alpha 0.0039 0.0152 0.0152
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0081 0.0438 0.0438
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0022 0.0047
Brugia malayi beta-NAC-like protein 0.0039 0.015 0.0229
Onchocerca volvulus 0.0123 0.0719 0.1107
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0039 0.0152 0.0152
Brugia malayi Muscleblind-like protein 0.0325 0.2079 0.3255
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0453 0.2942 1
Entamoeba histolytica P-glycoprotein 5, putative 0.0023 0.0047 0.0078
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0029 0.0026
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0184 0.0184
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0285 0.1808 0.283
Loa Loa (eye worm) RNA binding protein 0.007 0.0361 0.0554
Trypanosoma brucei protein kinase, putative 0.0111 0.0637 0.3146
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0122 0.0122
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0084 0.0456 0.0709
Brugia malayi Cytochrome P450 family protein 0.0017 0.0008 0.0006
Trypanosoma cruzi cruzipain precursor, putative 0.007 0.0364 0.1781
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0191 0.1176 0.1176
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0453 0.2942 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.0014 0.0014
Onchocerca volvulus 0.0045 0.0197 0.0287
Echinococcus multilocularis RUN 0.0043 0.0184 0.0184
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0651 0.0648
Echinococcus granulosus follistatin 0.0084 0.0456 0.0456
Toxoplasma gondii ABC1 family protein 0.004 0.0158 0.1144
Loa Loa (eye worm) hypothetical protein 0.0084 0.0456 0.0703
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0104 0.0104
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0067 0.0124
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0022 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Plasmodium vivax JmjC domain containing protein 0.0034 0.012 0.0844
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0158 0.051
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0188 0.09
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0361 0.0554
Brugia malayi MAP kinase sur-1 0.0111 0.0637 0.0993
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.2007 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0084 0.0456 0.0709
Schistosoma mansoni multidrug resistance protein 0.0023 0.0047 0.0044
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0039 0.0152 0.0149
Brugia malayi ecdysone receptor 0.0018 0.0014 0.0016
Echinococcus multilocularis dnaJ subfamily B 0.0889 0.5883 0.5883
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Schistosoma mansoni hypothetical protein 0.0053 0.0249 0.0246
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0015 0.0012
Onchocerca volvulus 0.0039 0.0152 0.0217
Mycobacterium ulcerans NAD synthetase 0.009 0.0501 0.1678
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0036 0.0135 0.0956
Brugia malayi prostaglandin transporter 0.0123 0.0719 0.1121
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0152 0.0152
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.015 0.071
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0064 0.0323 0.1576
Echinococcus multilocularis caspase 2 0.0065 0.0328 0.0328
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.023 0.0227
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0015 0.0015
Echinococcus multilocularis microtubule associated protein 2 0.15 1 1
Brugia malayi tailless protein 0.0018 0.0014 0.0016
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0158 0.051
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.012 0.0176
Loa Loa (eye worm) hypothetical protein 0.0123 0.0719 0.1115
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0019 0.0022 0.0022
Schistosoma mansoni protein phosphatase 2C 0.0034 0.012 0.0117
Echinococcus multilocularis expressed protein 0.0084 0.0456 0.0456
Leishmania major cathepsin L-like protease 0.0018 0.0015 0.0034
Brugia malayi nuclear hormone receptor family member odr-7 0.0018 0.0014 0.0016
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0113 0.0651 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0022 0.0053
Loa Loa (eye worm) hypothetical protein 0.0963 0.6379 1
Leishmania major basic transcription factor 3a, putative 0.0039 0.015 0.071
Entamoeba histolytica hypothetical protein 0.0039 0.015 0.0325
Schistosoma mansoni thyroid hormone receptor 0.0039 0.0152 0.0149
Leishmania major mitochondrial DNA polymerase beta 0.0314 0.2007 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4172 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0131 0.0776 0.0773
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0015 0.0015
Loa Loa (eye worm) ICD-1 protein 0.0039 0.015 0.0223
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0226
Brugia malayi sodium-independent organic anion transporter family protein 0.0123 0.0719 0.1121
Giardia lamblia Kinase, CMGC MAPK 0.0111 0.0637 0.0372
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.009 0.0501 0.0497
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0111 0.0637 0.3146
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0034 0.012 0.0844
Schistosoma mansoni smdr2 0.0023 0.0047 0.0044
Leishmania major NAD synthase, putative 0.009 0.0501 0.2463
Brugia malayi Pre-SET motif family protein 0.0034 0.0122 0.0184
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0158 0.0489
Trichomonas vaginalis glucosylceramidase, putative 0.0285 0.1808 0.4334
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0067 0.0124
Loa Loa (eye worm) hypothetical protein 0.0325 0.2079 0.325
Loa Loa (eye worm) hypothetical protein 0.0023 0.0046 0.0058
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0188 0.09
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0039 0.0152 0.0152
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0039 0.0152 0.0149
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Schistosoma mansoni phosphatidylserine receptor 0.0034 0.012 0.0117
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.023 0.0349
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0152 0.0152
Schistosoma mansoni survival motor neuron protein 0.0053 0.0249 0.0246
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0235
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0111 0.0637 0.3146
Schistosoma mansoni coup transcription factor 0.0039 0.0152 0.0149
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0003 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0014 0.0014
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0456 0.0703
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.015 0.1082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0032
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0023 0.0047 0.0047
Onchocerca volvulus 0.0018 0.0015 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0065 0.0328 0.0502
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0078 0.0348
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0039 0.0152 0.0149
Schistosoma mansoni tar DNA-binding protein 0.007 0.0361 0.0358
Brugia malayi hypothetical protein 0.0018 0.0012 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0078 0.0215
Schistosoma mansoni caspase-3 (C14 family) 0.0019 0.0022 0.0019
Loa Loa (eye worm) multidrug resistance protein 3 0.0023 0.0047 0.0061
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0047 0.0113
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0036 0.0135 0.0135
Trichomonas vaginalis esterase, putative 0.004 0.0158 0.0379
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Echinococcus granulosus caspase 8 0.0019 0.0022 0.0022
Entamoeba histolytica P-glyco protein 6, putative 0.0023 0.0047 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Brugia malayi hypothetical protein 0.0123 0.0719 0.1121
Brugia malayi Cathepsin L-like precursor 0.0018 0.0015 0.0017
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0039 0.0152 0.0149
Brugia malayi Cytochrome P450 family protein 0.0029 0.0085 0.0127
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0022 0.0025
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0036 0.0135 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0023 0.0047 0.0113
Schistosoma mansoni phd/f-box containing protein 0.0034 0.012 0.0117
Mycobacterium ulcerans GMP synthase 0.0036 0.0135 0.043
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0158 0.0158
Leishmania major hypothetical protein, conserved 0.004 0.0158 0.0749
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0018 0.0014 0.0011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.2007 1
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0047 0.0047
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0039 0.0152 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0022 0.0053
Brugia malayi nuclear hormone receptor 0.0018 0.0014 0.0016
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0191 0.1176 0.1176
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1149 0.2754
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0184 0.0184
Echinococcus granulosus mitogen activated protein kinase 0.0111 0.0637 0.0637
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0078 0.0215
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0067 0.0199
Trypanosoma brucei metacaspase 0.0019 0.0022 0.0069
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0158 0.0379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.007 0.0364 0.1781
Schistosoma mansoni loxhd1 0.0043 0.0184 0.018
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.0637 0.1527
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0204 0.1265 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0015 0.0015
Mycobacterium tuberculosis Conserved protein 0.004 0.0158 0.0489
Echinococcus multilocularis lysine specific demethylase 6a 0.0034 0.012 0.012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0136 0.0414
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0022 0.0053
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0047 0.0113
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0067 0.0124
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0158 0.0235
Loa Loa (eye worm) DR-78 0.0018 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.015 0.036
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0023 0.0047 0.0258
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0184 0.1348
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0158 0.0749
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0453 0.2942 0.6649
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0067 0.0199
Loa Loa (eye worm) inositol-1 0.0041 0.0165 0.0246
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0067 0.0199
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0122 0.0852
Toxoplasma gondii histone lysine methyltransferase SET1 0.0119 0.0696 0.5448
Schistosoma mansoni nuclear receptor 0.0018 0.0014 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0067 0.0098
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0047 0.0113
Giardia lamblia Fructose-bisphosphate aldolase 0.0635 0.4172 1
Onchocerca volvulus 0.0018 0.0015 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0022 0.0053
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0023 0.0047 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0085 0.012
Brugia malayi Cytochrome P450 family protein 0.0017 0.0008 0.0006
Brugia malayi hypothetical protein 0.0021 0.0029 0.0039
Entamoeba histolytica hypothetical protein 0.004 0.0158 0.0344
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0039 0.0152 0.0152
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0152 0.0149
Leishmania major hypothetical protein, conserved 0.0028 0.0078 0.0348
Onchocerca volvulus 0.004 0.0158 0.0226
Brugia malayi hypothetical protein 0.0018 0.0014 0.0016
Echinococcus granulosus Solute carrier organic anion transporter family 0.0123 0.0719 0.0719
Echinococcus multilocularis cysteine protease 0.0018 0.0015 0.0015
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0165 0.0361
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0015 0.0015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0039 0.0152 0.0149
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0635 0.4172 1
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0158 0.0155
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0047 0.0113
Onchocerca volvulus 0.0026 0.0067 0.0083
Schistosoma mansoni multidrug resistance protein 0.0023 0.0047 0.0044
Schistosoma mansoni inositol monophosphatase 0.0041 0.0165 0.0162
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Mycobacterium ulcerans hypothetical protein 0.0165 0.1006 0.34
Echinococcus multilocularis pol protein 0.1072 0.7117 0.7117
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0014 0.0014
Trichomonas vaginalis abcb9, putative 0.0023 0.0047 0.0113
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.0014 0.0009
Onchocerca volvulus Glucosylceramidase homolog 0.0187 0.1149 0.1783
Brugia malayi ABC transporter family protein 0.0023 0.0047 0.0068
Schistosoma mansoni cpg binding protein 0.0066 0.0335 0.0332
Onchocerca volvulus Putative organic anion transporter 0.0123 0.0719 0.1107
Plasmodium vivax SET domain protein, putative 0.0034 0.0122 0.0852
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0003 0.0003
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0123 0.0719 0.0719
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0029 0.0029
Trichomonas vaginalis ABC transporter, putative 0.0023 0.0047 0.0113
Plasmodium falciparum multidrug resistance protein 1 0.0023 0.0047 0.011
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0039 0.0152 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0039 0.0152 0.0233
Trypanosoma cruzi cysteine peptidase, putative 0.007 0.0364 0.1781
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Echinococcus multilocularis pol protein 0.1072 0.7117 0.7117
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0078 0.0348
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0314 0.2007 1
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.0753 0.1169
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0022 0.0053
Schistosoma mansoni thyroid hormone receptor 0.0039 0.0152 0.0149
Brugia malayi CXXC zinc finger family protein 0.0062 0.0311 0.0482
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0022 0.0056
Schistosoma mansoni transcription factor btf3 0.0039 0.015 0.0147
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0015 0.0034
Onchocerca volvulus Putative organic anion transporter 0.0123 0.0719 0.1107
Trypanosoma brucei NAD+ synthase, putative 0.009 0.0501 0.2463
Echinococcus granulosus multidrug resistance protein 1 0.0023 0.0047 0.0047
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0036 0.0135 0.0408
Brugia malayi Melibiase family protein 0.0075 0.0398 0.0618
Schistosoma mansoni nuclear receptor 0.0018 0.0014 0.0011
Brugia malayi glutaminase DH11.1 0.0301 0.1921 0.3006
Brugia malayi multidrug resistance protein 3 0.0023 0.0047 0.0068
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0398 0.0954
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0015 0.0036
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0023 0.0047 0.0113
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0015 0.0001
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.015 0.0325
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0249 0.0384
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0039 0.0152 0.0233
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0015 0.0036
Trypanosoma brucei RNA helicase, putative 0.0106 0.0608 0.2999
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0022 0.0053
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0034 0.012 0.0561

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 64 uM Inhibition of MK2 ChEMBL. 17570666
IC50 (binding) = 64 uM Inhibition of MK2 ChEMBL. 17570666

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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