Detailed information for compound 505292

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 572.723 | Formula: C34H46F2O5
  • H donors: 0 H acceptors: 1 LogP: 11.96 Rotable bonds: 21
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCCCOc1ccc(cc1)c1coc2c(c1=O)c(OCCCCCCCCC)cc(c2)OC(F)F
  • InChi: 1S/C34H46F2O5/c1-3-5-7-9-11-13-15-21-38-27-19-17-26(18-20-27)29-25-40-31-24-28(41-34(35)36)23-30(32(31)33(29)37)39-22-16-14-12-10-8-6-4-2/h17-20,23-25,34H,3-16,21-22H2,1-2H3
  • InChiKey: WVEBAALQFWUCHO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei hypothetical protein 0.0113 0.1044 0.3532
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0208 0.0666
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Brugia malayi brahma associated protein 60 kDa 0.0042 0.0335 0.1057
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0243 0.0814
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0408 0.1286
Loa Loa (eye worm) brahma associated protein 0.0042 0.0335 0.1057
Echinococcus granulosus hypothetical protein 0.0027 0.0185 0.0185
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0039 0.0302 0.0436
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0015 0.0061 0.0479
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0312 0.0983
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0491 0.1725
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0067 0.0067
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0121 0.0368
Trypanosoma cruzi DNA damage repair protein, putative 0.001 0.0014 0.0032
Plasmodium falciparum thioredoxin reductase 0.0016 0.0075 0.1637
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0018 0.0094 0.0132
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0151 0.0471
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0201 0.0201
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0017 0.008 0.0644
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0191 0.0601
Mycobacterium ulcerans hypothetical protein 0.0158 0.1501 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0447
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0985
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0243 0.1047
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0075 0.021
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.1239 0.4219
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0015 0.0061 0.016
Brugia malayi YY1-associated factor 2 0.0015 0.0061 0.0191
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0009 0.0009
Echinococcus multilocularis caspase 2 0.0027 0.0178 0.0178
Brugia malayi Pre-SET motif family protein 0.0031 0.0218 0.0688
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0096 0.2199
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0094 0.0094
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0491 0.3209
Onchocerca volvulus Cell death protein 3 homolog 0.0027 0.0178 0.0769
Echinococcus multilocularis thyroid hormone receptor alpha 0.0179 0.1712 0.1712
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.1125 0.4357
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0022 0.0022
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0067 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0302 0.0951
Schistosoma mansoni DNA helicase recq1 0.0019 0.0096 0.0135
Echinococcus multilocularis ecdysone induced protein 78C 0.0039 0.0302 0.0302
Schistosoma mansoni lamin 0.0027 0.0183 0.0262
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0015 0.0061 0.0191
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0042 0.0335 0.0335
Schistosoma mansoni caspase-7 (C14 family) 0.0027 0.0178 0.0255
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0077 0.0247
Echinococcus granulosus snurportin 1 0.0306 0.2989 0.2989
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.0094 0.0094
Treponema pallidum NADH oxidase 0.0016 0.0075 1
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0015 0.0061 0.0192
Brugia malayi Nuclear hormone receptor-like 1 0.0039 0.0302 0.0951
Schistosoma mansoni hypothetical protein 0.0027 0.0185 0.0265
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0198 0.0198
Onchocerca volvulus 0.0015 0.0061 0.0261
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0143 0.055
Schistosoma mansoni ran 0.0021 0.0121 0.0172
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0247 0.0779
Schistosoma mansoni hypothetical protein 0.0034 0.025 0.0361
Onchocerca volvulus Protein ultraspiracle homolog 0.0039 0.0302 0.13
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0256 0.2486 1
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0735 0.5932
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1176 0.7812
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0389 0.1313
Brugia malayi Pre-SET motif family protein 0.021 0.2027 0.639
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0142 0.1138
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.1176 0.1176
Echinococcus multilocularis musashi 0.0027 0.0183 0.0183
Schistosoma mansoni terminal deoxycytidyl transferase 0.0034 0.0247 0.0356
Loa Loa (eye worm) hypothetical protein 0.0033 0.0243 0.0766
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0302 0.0436
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.01 0.0916 0.0916
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0039 0.0302 0.0951
Schistosoma mansoni hypothetical protein 0.0073 0.064 0.0933
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0034 0.0247 0.0247
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1176 0.172
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0096 0.0304
Brugia malayi Ubiquitin-like protein SMT3 0.003 0.0216 0.0681
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0116 0.0116
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0075 0.0256
Echinococcus granulosus GPCR family 2 0.0016 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0703
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0094 0.0297
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0198 0.063
Loa Loa (eye worm) hypothetical protein 0.015 0.1425 0.4491
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0094 0.0406
Leishmania major small ubiquitin protein, putative 0.003 0.0216 0.0693
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0151 0.0471
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.4002 0.4002
Echinococcus multilocularis ubiquitin 0.0011 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0312 0.0312
Echinococcus granulosus microtubule associated protein 2 0.0685 0.6814 0.6814
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Echinococcus multilocularis GPCR, family 2 0.0016 0.0067 0.0067
Echinococcus multilocularis dna polymerase kappa 0.006 0.0513 0.0513
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0243 0.0766
Brugia malayi hypothetical protein 0.0027 0.0185 0.0584
Toxoplasma gondii thioredoxin reductase 0.0048 0.0389 0.3281
Loa Loa (eye worm) hypothetical protein 0.0027 0.0185 0.0584
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0208 0.0666
Brugia malayi orphan nuclear receptor NR2E1 0.0018 0.0094 0.0297
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0243 0.2035
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0031 0.0098
Schistosoma mansoni hypothetical protein 0.0027 0.0185 0.0265
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0951
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0008 0.0025
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0408 0.1286
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0491 0.3209
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.1239 0.42
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0014 0.0032
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1176 0.7812
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0151 0.1216
Echinococcus granulosus peroxidasin 0.0028 0.0191 0.0191
Trypanosoma brucei metacaspase 5, putative 0.0027 0.0178 0.0564
Trypanosoma brucei trypanothione reductase 0.0048 0.0389 0.1285
Brugia malayi tumor suppressor. 0.0324 0.3172 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0513 0.1738
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Echinococcus granulosus zinc finger protein Ran binding 0.0015 0.0061 0.0061
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0178 0.0594
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0075 0.0242
Loa Loa (eye worm) hypothetical protein 0.0015 0.0061 0.0191
Echinococcus multilocularis protein quaking 0.0027 0.0185 0.0185
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0075 0.0413
Brugia malayi hypothetical protein 0.0018 0.0094 0.0297
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0077 0.0242
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0183 0.0576
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0312 0.1052
Brugia malayi CXXC zinc finger family protein 0.0029 0.0196 0.0619
Trypanosoma brucei calpain, putative 0.0113 0.1044 0.3532
Echinococcus granulosus dnaJ subfamily B 0.0406 0.4002 0.4002
Plasmodium falciparum importin beta, putative 0.0029 0.0198 0.4899
Chlamydia trachomatis pyruvate kinase 0.0033 0.0243 0.6446
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0116 0.0367
Trypanosoma cruzi DNA polymerase eta, putative 0.001 0.0014 0.0032
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0075 0.1918
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0218 0.0314
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0312 0.1285
Echinococcus granulosus jun protein 0.0089 0.0809 0.0809
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0121 0.0383
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0096 0.0096
Loa Loa (eye worm) beta-lactamase 0.004 0.0312 0.0985
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0075 0.021
Trypanosoma brucei calpain-like protein, putative 0.0113 0.1044 0.3532
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0389 0.0389
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0075 0.1637
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0513 0.3357
Loa Loa (eye worm) hypothetical protein 0.0015 0.0061 0.0191
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0951
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0077 0.0242
Brugia malayi hypothetical protein 0.0016 0.0072 0.0227
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0039 0.0302 0.0302
Echinococcus granulosus transcription factor Dp 1 0.0076 0.0679 0.0679
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.008 0.0648
Echinococcus granulosus intermediate filament protein 0.0027 0.0183 0.0183
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0312 0.0452
Onchocerca volvulus 0.004 0.0312 0.1347
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.0094 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0039 0.0302 0.0951
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0363 0.1504
Schistosoma mansoni hypothetical protein 0.0016 0.0067 0.0092
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0042 0.0335 0.2824
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.0562
Loa Loa (eye worm) hypothetical protein 0.0049 0.0408 0.1286
Echinococcus granulosus importin subunit beta 1 0.0029 0.0198 0.0198
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0389 0.0389
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0113 0.1044 0.3532
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0491 0.0714
Echinococcus multilocularis FTZ F1 alpha 0.0039 0.0302 0.0302
Brugia malayi hypothetical protein 0.007 0.0616 0.1941
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0015 0.0061 0.0261
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0985
Chlamydia trachomatis SWIB complex protein 0.0042 0.0335 1
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0243 0.0983
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0039 0.0302 0.0951
Onchocerca volvulus 0.007 0.0616 0.2655
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0075 0.0242
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0075 0.1918
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.1339 0.4561
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1044 0.3532
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1044 0.3532
Onchocerca volvulus 0.0239 0.2319 1
Schistosoma mansoni hypothetical protein 0.0011 0.0022 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0039 0.0302 0.0951
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.1044 0.3553
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0015 0.0061 0.0192
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1044 0.3553
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.0247 0.0779
Trypanosoma cruzi DNA damage repair protein, putative 0.001 0.0014 0.0032
Leishmania major DNA polymerase eta, putative 0.0034 0.0247 0.0799
Loa Loa (eye worm) tumor suppressor 0.0324 0.3172 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0039 0.0302 0.0302
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0513 0.1738
Plasmodium falciparum pyruvate kinase 0.0033 0.0243 0.6107
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0089 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0146 0.1386 0.437
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0039 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0161 0.3931
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0513 0.2157
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0039 0.0302 0.0436
Schistosoma mansoni lamin 0.0027 0.0183 0.0262
Brugia malayi brahma associated protein 60 kDa 0.0042 0.0335 0.1057
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0015 0.0061 0.0192
Giardia lamblia DINP protein human, muc B family 0.004 0.0313 1
Onchocerca volvulus 0.0146 0.1386 0.5978
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0312 0.0452
Onchocerca volvulus 0.0039 0.0302 0.13
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0143 0.055
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1044 0.3532
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0389 0.1301
Brugia malayi Blistered cuticle protein 3 0.0028 0.0191 0.0601
Schistosoma mansoni hypothetical protein 0.0348 0.342 0.5016
Schistosoma mansoni hypothetical protein 0.0306 0.2989 0.4383
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1044 0.3532
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.1003 0.3851
Schistosoma mansoni retinoic acid receptor RXR 0.0039 0.0302 0.0436
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0465 0.3929
Onchocerca volvulus 0.0015 0.0061 0.0261
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0312 0.2007
Plasmodium falciparum pyruvate kinase 2 0.0017 0.008 0.1773
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0334 0.1126
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1176 0.172
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0015 0.0061 0.016
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.1339 0.4543
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1044 0.3532
Schistosoma mansoni RNA binding protein 0.0015 0.0061 0.0082
Loa Loa (eye worm) RecQ helicase 0.0045 0.0363 0.1144
Echinococcus granulosus lamin 0.0027 0.0183 0.0183
Echinococcus multilocularis transcription factor Dp 1 0.0076 0.0679 0.0679
Mycobacterium leprae Probable lipase LipE 0.004 0.0312 0.0787
Plasmodium vivax glutathione reductase, putative 0.0048 0.0389 1
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0191 0.0601
Entamoeba histolytica deoxycytidyl transferase, putative 0.0034 0.0247 0.1987
Brugia malayi steroid hormone receptor 0.0039 0.0302 0.0951
Toxoplasma gondii ran binding protein 0.0015 0.0061 0.0479
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0018 0.0094 0.0406
Schistosoma mansoni thyroid hormone receptor 0.0179 0.1712 0.2507
Schistosoma mansoni zinc finger protein 0.0018 0.0094 0.0132
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.0562
Schistosoma mansoni hypothetical protein 0.0015 0.0061 0.0082
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0312 0.0983
Leishmania major hypothetical protein, conserved 0.0015 0.0061 0.016
Schistosoma mansoni hypothetical protein 0.0348 0.342 0.5016
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0075 0.021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0312 0.0312
Leishmania major DNA polymerase kappa, putative 0.004 0.0313 0.1025
Schistosoma mansoni RAR-like nuclear receptor 0.0039 0.0302 0.0436
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0075 0.0104
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0335 0.0335
Plasmodium falciparum metacaspase 1 0.0027 0.0178 0.4386
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0513 0.1738
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0031 0.0098
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0161 0.3931
Onchocerca volvulus 0.004 0.0312 0.1347
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0243 0.0766
Schistosoma mansoni hypothetical protein 0.0016 0.0067 0.0092
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0312 0.1285
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0243 0.0766
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0491 0.1548
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0951
Loa Loa (eye worm) hypothetical protein 0.0015 0.0061 0.0191
Schistosoma mansoni fusion 0.0015 0.0061 0.0082
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0302 0.0951
Brugia malayi RNA, U transporter 1 0.0081 0.073 0.23
Mycobacterium ulcerans hypothetical protein 0.004 0.0312 0.2007
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0178 0.1484
Trichomonas vaginalis set domain proteins, putative 0.0239 0.2319 1
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0116 0.0367
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0014
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0243 0.0766
Loa Loa (eye worm) hypothetical protein 0.0137 0.1288 0.4062
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0096 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0703
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0161 0.0536
Echinococcus multilocularis tumor protein p63 0.1001 1 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0075 0.0237
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0218 0.0218
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0334 0.1126
Brugia malayi nuclear hormone receptor family member nhr-6 0.0018 0.0094 0.0297
Giardia lamblia Sentrin 0.003 0.0216 0.6757
Onchocerca volvulus 0.0015 0.0061 0.0261
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.1044 0.3553
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0218 0.0314
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.1176 0.4565
Schistosoma mansoni ran 0.0021 0.0121 0.0172
Onchocerca volvulus 0.0027 0.0183 0.0788
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0015 0.0061 0.0191
Brugia malayi hypothetical protein 0.0021 0.0116 0.0367
Echinococcus multilocularis ring and YY1 binding protein 0.0015 0.0061 0.0061
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0077 0.0215
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0243 0.0766
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0096 0.0096
Schistosoma mansoni pyruvate kinase 0.0033 0.0243 0.035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0302 0.0302
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0161 0.1339
Schistosoma mansoni hypothetical protein 0.014 0.1319 0.193
Loa Loa (eye worm) hypothetical protein 0.015 0.1425 0.4491
Schistosoma mansoni cpg binding protein 0.003 0.0213 0.0306
Echinococcus granulosus protein quaking 0.0027 0.0185 0.0185
Plasmodium vivax hypothetical protein, conserved 0.004 0.0312 0.8029
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0096 0.2756
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0178 0.1484
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.1003 0.3851
Loa Loa (eye worm) hypothetical protein 0.0082 0.0735 0.2319
Leishmania major hypothetical protein, conserved 0.0015 0.0061 0.016
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1044 0.3532
Giardia lamblia Pyruvate kinase 0.0033 0.0243 0.7654
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0075 0.0242
Schistosoma mansoni steroid hormone receptor ad4bp 0.0039 0.0302 0.0436
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0039 0.0302 0.0302
Brugia malayi polk-prov protein 0.0037 0.028 0.0883
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.0247 0.0356
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0075 0.0256
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Schistosoma mansoni pyruvate kinase 0.0033 0.0243 0.035
Loa Loa (eye worm) hypothetical protein 0.0013 0.0036 0.0114
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0142 0.0447
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0243 0.0785
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0015 0.0061 0.0061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0027 0.0178 0.056
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0312 0.1285
Schistosoma mansoni intermediate filament proteins 0.0027 0.0183 0.0262
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0042 0.0335 0.862
Loa Loa (eye worm) hypothetical protein 0.0021 0.0116 0.0367
Plasmodium falciparum metacaspase-like protein 0.0027 0.0178 0.4386
Trypanosoma cruzi metacaspase, putative 0.0027 0.0178 0.0594
Echinococcus granulosus lamin dm0 0.0027 0.0183 0.0183
Brugia malayi tailless protein 0.0018 0.0094 0.0297
Echinococcus multilocularis pyruvate kinase 0.0026 0.0172 0.0172
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0075 0.5
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0075 0.0242
Leishmania major metacaspase, putative 0.0027 0.0178 0.0564
Echinococcus granulosus pyruvate kinase 0.0033 0.0243 0.0243
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0267 0.0386
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0075 0.0075
Brugia malayi nuclear receptor NHR-88 0.0039 0.0302 0.0951
Loa Loa (eye worm) hypothetical protein 0.0021 0.0116 0.0367
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0039 0.0302 0.13
Loa Loa (eye worm) histone methyltransferase 0.001 0.0009 0.0029
Echinococcus multilocularis jun protein 0.0089 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0025 0.0161 0.0508
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.053 0.0771
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.014 0.1319 0.1319
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0312 0.2007
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0067 0.0067
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 0.2989 0.9425
Trypanosoma cruzi metacaspase, putative 0.0027 0.0178 0.0594
Brugia malayi hypothetical protein 0.0028 0.0191 0.0601
Loa Loa (eye worm) hypothetical protein 0.0016 0.0067 0.0211
Onchocerca volvulus Dual oxidase homolog 0.0028 0.0191 0.0822
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0312 0.0983
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0735 0.5932
Trypanosoma brucei mitochondrial DNA polymerase beta 0.03 0.2931 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0015 0.0061 0.0191
Echinococcus multilocularis snurportin 1 0.0306 0.2989 0.2989
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0312 0.1285
Echinococcus multilocularis dna polymerase eta 0.0034 0.0247 0.0247
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0313 0.0986
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0363 0.0363
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0178 0.4575
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0302 0.0302
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0018 0.0094 0.0297
Schistosoma mansoni cpg binding protein 0.003 0.0213 0.0306
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0094 0.0132
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.0094 0.0297
Trypanosoma brucei small ubiquitin-related modifier 0.003 0.0216 0.0693
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0061 0.016
Echinococcus multilocularis zinc finger protein Ran binding 0.0015 0.0061 0.0061
Echinococcus multilocularis microtubule associated protein 2 0.0685 0.6814 0.6814
Leishmania major pyruvate kinase 0.0033 0.0243 0.0785
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0132 0.1239 0.1239
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0094 0.0094
Trypanosoma cruzi small ubiquitin protein, putative 0.003 0.0216 0.0723
Onchocerca volvulus 0.0028 0.0191 0.0822
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0304
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1044 0.3532
Brugia malayi nuclear hormone receptor 0.0039 0.0302 0.0951
Brugia malayi beta-lactamase 0.004 0.0312 0.0985
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0056 0.0175
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0121 0.0399
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0491 0.0491
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0196 0.0619
Echinococcus granulosus ubiquitin 0.0011 0.0016 0.0016
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.0094 0.0094
Schistosoma mansoni coup transcription factor 0.0039 0.0302 0.0436
Toxoplasma gondii ABC1 family protein 0.004 0.0312 0.2628
Loa Loa (eye worm) hypothetical protein 0.0034 0.025 0.0788
Schistosoma mansoni nuclear receptor nhr-48 0.0018 0.0094 0.0132
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.1125 0.4357
Echinococcus granulosus pyruvate kinase 0.0017 0.008 0.008
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0308 0.7837
Onchocerca volvulus 0.0031 0.0218 0.0941
Onchocerca volvulus 0.0018 0.0094 0.0406
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0191 0.0601
Onchocerca volvulus 0.0027 0.0183 0.0788
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0491 0.1636
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0039 0.0302 0.0436
Onchocerca volvulus Peroxidase homolog 0.0028 0.0191 0.0822
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.014 0.1319 0.1319
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0132 0.1239 0.3907
Schistosoma mansoni hypothetical protein 0.0055 0.0463 0.0673
Leishmania major hypothetical protein, conserved 0.0015 0.0061 0.016
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0985
Onchocerca volvulus 0.0028 0.0191 0.0822
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0151 0.0586
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0513 0.1711
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0985
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0039 0.0302 0.0302
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.001 0.0032
Echinococcus granulosus pyruvate kinase 0.0017 0.008 0.008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0075 0.021
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0075 0.5
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.2027 0.639
Mycobacterium ulcerans lipase LipD 0.004 0.0312 0.2007
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0015 0.0061 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0703
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0427 0.1443
Leishmania major cytochrome p450-like protein 0.0017 0.0077 0.0215
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0018 0.0094 0.0094
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.1044 0.3553
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0015 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0034 0.0247 0.0779
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0015 0.0061 0.0061
Schistosoma mansoni cellular tumor antigen P53 0.0146 0.1386 0.2029
Giardia lamblia Pyruvate kinase 0.0017 0.008 0.2222
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0116 0.0164
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0039 0.0302 0.0951
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Brugia malayi beta-lactamase family protein 0.004 0.0312 0.0985
Echinococcus granulosus dna polymerase eta 0.0034 0.0247 0.0247
Trypanosoma brucei unspecified product 0.0053 0.0447 0.1485
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0075 0.021
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0363 0.1144
Leishmania major pyruvate kinase 0.0033 0.0243 0.0785
Loa Loa (eye worm) steroid hormone receptor 0.0039 0.0302 0.0951
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Loa Loa (eye worm) hypothetical protein 0.0087 0.0784 0.2472
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0042 0.0335 0.8572
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0116 0.0164
Entamoeba histolytica recQ family DNA helicase 0.0009 0.0004 0.0029
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0183 0.0576
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0151 0.0502
Toxoplasma gondii ImpB/MucB/SamB family protein 0.001 0.0014 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0116 0.0116
Schistosoma mansoni DNA polymerase IV / kappa 0.001 0.0014 0.0014
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0191 0.0601
Brugia malayi SWIB/MDM2 domain containing protein 0.0042 0.0335 0.1057
Brugia malayi hypothetical protein 0.0018 0.0094 0.0297
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0312 0.0983
Loa Loa (eye worm) hypothetical protein 0.0021 0.0116 0.0367
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.03 0.2931 1
Onchocerca volvulus Peroxidase homolog 0.0028 0.0191 0.0822
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0075 0.0242
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0452 0.1425
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0039 0.0302 0.0436
Onchocerca volvulus 0.0015 0.0061 0.0261
Onchocerca volvulus 0.0018 0.0094 0.0406
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0161 0.0505
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0302 0.0951
Echinococcus multilocularis pyruvate kinase 0.0033 0.0243 0.0243
Echinococcus multilocularis pyruvate kinase 0.0017 0.008 0.008
Brugia malayi beta-lactamase family protein 0.004 0.0312 0.0985
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.025 0.0788
Trypanosoma cruzi WLM domain containing protein, putative 0.0015 0.0061 0.0192
Entamoeba histolytica hypothetical protein 0.0023 0.0143 0.1148
Brugia malayi intermediate filament protein 0.0027 0.0183 0.0576
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0198 0.1649
Trypanosoma brucei metacaspase MCA2 0.0027 0.0178 0.0564
Loa Loa (eye worm) SMO-1 protein 0.003 0.0216 0.0681
Echinococcus multilocularis geminin 0.0348 0.342 0.342
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0121 0.0121
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0075 0.0413
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.028 0.0912
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0247 0.0829
Brugia malayi Importin beta-1 subunit 0.0029 0.0198 0.0623
Loa Loa (eye worm) hypothetical protein 0.0013 0.0041 0.0129
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0039 0.0302 0.0436
Trypanosoma brucei DNA polymerase IV, putative 0.0053 0.0447 0.1485
Echinococcus multilocularis lamin dm0 0.0027 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0029 0.0198 0.0623
Plasmodium falciparum thioredoxin reductase 0.0048 0.0389 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0116 0.0367
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0096 0.0784
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0017 0.0077 0.0422
Schistosoma mansoni thyroid hormone receptor 0.0179 0.1712 0.2507
Echinococcus granulosus Zinc finger RanBP2 type 0.0015 0.0061 0.0061
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0015 0.0061 0.0191
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0009 0.0009
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0334 0.1126
Schistosoma mansoni caspase-3 (C14 family) 0.01 0.0916 0.1339
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0075 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0039 0.0302 0.0951
Toxoplasma gondii small ubiquitin family modifier, putative 0.003 0.0216 0.1806
Schistosoma mansoni pyruvate kinase 0.0017 0.008 0.0111
Echinococcus granulosus dna polymerase kappa 0.006 0.0513 0.0513
Brugia malayi nuclear receptor NHR-67 0.0018 0.0094 0.0297
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0056 0.0175
Echinococcus multilocularis Small ubiquitin modifier 2 0.003 0.0216 0.0216
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0216 0.5542
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0096 0.0304
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0075 0.0075
Echinococcus multilocularis caspase 0.01 0.0916 0.0916
Loa Loa (eye worm) DR-78 0.0018 0.0094 0.0297
Trypanosoma cruzi WLM domain containing protein, putative 0.0015 0.0061 0.0192
Plasmodium vivax SET domain protein, putative 0.0031 0.0218 0.5602
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0041 0.0041
Schistosoma mansoni DNA polymerase eta 0.0034 0.0247 0.0356
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Schistosoma mansoni hypothetical protein 0.0016 0.0067 0.0092
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0951
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0243 0.1047
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0243 0.0695
Loa Loa (eye worm) hypothetical protein 0.0021 0.0116 0.0367
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0039 0.0302 0.0951
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.0094 0.0297
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0212 0.1774
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0335 0.862
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0039 0.0302 0.0951
Mycobacterium leprae conserved hypothetical protein 0.004 0.0312 0.0787
Schistosoma mansoni hypothetical protein 0.0042 0.0335 0.0486
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0312 0.0983
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0208 0.0666
Schistosoma mansoni jun-related protein 0.0073 0.064 0.0933
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0363 0.1504
Loa Loa (eye worm) hypothetical protein 0.0037 0.028 0.0883
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0161 0.4135
Trypanosoma brucei unspecified product 0.0023 0.0142 0.0439
Brugia malayi Steroid receptor seven-up type 2 0.0039 0.0302 0.0951
Trypanosoma brucei unspecified product 0.0023 0.0142 0.0439
Mycobacterium tuberculosis Conserved hypothetical protein 0.0158 0.1501 0.5915
Echinococcus multilocularis cpg binding protein 0.003 0.0213 0.0213
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0389 0.1226
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0075 0.021
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0389 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0067 0.0211
Echinococcus multilocularis pyruvate kinase 0.0017 0.008 0.008
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0191 0.0601
Schistosoma mansoni hypothetical protein 0.0042 0.0335 0.0486
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Mycobacterium tuberculosis Conserved protein 0.004 0.0312 0.0983
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0335 0.0335
Brugia malayi glutathione reductase 0.0048 0.0389 0.1226
Schistosoma mansoni importin beta-1 0.0029 0.0198 0.0284
Plasmodium falciparum glutathione reductase 0.0016 0.0075 0.1637
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0039 0.0302 0.0951
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0218 0.0218
Onchocerca volvulus 0.0028 0.0191 0.0822
Trypanosoma brucei DNA polymerase eta, putative 0.0034 0.0247 0.0799
Plasmodium vivax importin-beta 2, putative 0.0029 0.0198 0.5071
Mycobacterium tuberculosis Conserved protein 0.004 0.0312 0.0983
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0121 0.2867
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0198 0.063
Plasmodium vivax small ubiquitin-related modifier, putative 0.003 0.0216 0.5546
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0312 0.1052
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0143 0.055
Brugia malayi nuclear hormone receptor family member odr-7 0.0018 0.0094 0.0297
Plasmodium vivax DNA repair protein REV1, putative 0.001 0.0014 0.0337
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0243 0.1539
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0039 0.0302 0.0951
Loa Loa (eye worm) hypothetical protein 0.0009 0.0003 0.0009
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0183 0.0576
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0075 0.0413
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0161 0.0536
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0985
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0132 0.1239 0.4219
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0191 0.0601
Onchocerca volvulus Bile acid receptor homolog 0.0039 0.0302 0.13
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0243 0.0983
Loa Loa (eye worm) hypothetical protein 0.0031 0.0218 0.0688
Brugia malayi Cytochrome P450 family protein 0.0017 0.0077 0.0242
Trichomonas vaginalis esterase, putative 0.004 0.0312 0.1285
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0039 0.0302 0.0302
Onchocerca volvulus 0.0011 0.0016 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0039 0.0302 0.0951
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1044 0.3532
Schistosoma mansoni peroxidasin 0.0028 0.0191 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0039 0.0302 0.0951
Leishmania major hypothetical protein, conserved 0.0015 0.0061 0.016
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0513 0.2157
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0312 0.1285
Echinococcus multilocularis caspase 3 0.0073 0.0647 0.0647
Echinococcus granulosus muscleblind protein 0.015 0.1425 0.1425
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0143 0.0473
Schistosoma mansoni caspase-7 (C14 family) 0.01 0.0916 0.1339
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0077 0.0247
Brugia malayi ecdysone receptor 0.0018 0.0094 0.0297
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0113 0.1044 0.3553
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0132 0.1239 0.3907
Brugia malayi Muscleblind-like protein 0.015 0.1425 0.4491
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0218 0.1825
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0513 0.1738
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0075 0.021
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0094 0.0132
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0951
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0243 0.0785
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0243 0.1047
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0027 0.0178 0.0562
Leishmania major mitochondrial DNA polymerase beta 0.03 0.2931 1
Entamoeba histolytica hypothetical protein 0.0011 0.0016 0.0126
Loa Loa (eye worm) blistered cuticle protein 3 0.0028 0.0191 0.0601
Echinococcus granulosus cpg binding protein 0.003 0.0213 0.0213
Echinococcus granulosus SWI:SNF matrix associated 0.0042 0.0335 0.0335
Echinococcus granulosus bloom syndrome protein 0.0045 0.0363 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0039 0.0302 0.0951
Brugia malayi nuclear receptor RXR 0.0018 0.0094 0.0297
Brugia malayi hypothetical protein 0.0021 0.0116 0.0367
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0094 0.0094
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0243 0.0814
Schistosoma mansoni nuclear receptor 0.0018 0.0094 0.0132
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0218 0.0314
Plasmodium vivax metacaspase 1, putative 0.0027 0.0178 0.4575
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0191 0.0822
Echinococcus multilocularis lamin 0.0027 0.0183 0.0183
Onchocerca volvulus 0.0042 0.0335 0.1446
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.01 0.0916 0.0916
Leishmania major trypanothione reductase 0.0048 0.0389 0.1285
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0061 0.016
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0018 0.0094 0.0132
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0015 0.0061 0.0192
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.1003 0.3851
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0075 0.021
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.0094 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0039 0.0302 0.0951
Entamoeba histolytica Ran family GTPase 0.0021 0.0121 0.0973
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0042 0.0335 0.0335
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0313 0.1025
Mycobacterium ulcerans beta-lactamase 0.004 0.0312 0.2007
Onchocerca volvulus 0.0029 0.0196 0.0847
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0042 0.0335 0.2824
Loa Loa (eye worm) hypothetical protein 0.0013 0.0036 0.0114
Toxoplasma gondii hypothetical protein 0.0048 0.0396 0.3347
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.03 0.2931 1
Echinococcus granulosus pyruvate kinase 0.0033 0.0243 0.0243
Brugia malayi Peroxidasin 0.0028 0.0191 0.0601
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.1125 0.4357
Onchocerca volvulus 0.004 0.0312 0.1347
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0703
Mycobacterium tuberculosis Conserved protein 0.004 0.0312 0.0983
Echinococcus multilocularis peroxidasin 0.0028 0.0191 0.0191
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0075 0.1637
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0075 0.0242
Echinococcus granulosus Small ubiquitin modifier 2 0.003 0.0216 0.0216
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0121 0.0399
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0183 0.0576
Plasmodium falciparum glutathione reductase 0.0048 0.0389 1
Brugia malayi Temporarily assigned gene name protein 44 0.0027 0.0185 0.0584
Loa Loa (eye worm) hypothetical protein 0.0015 0.0061 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Echinococcus granulosus ecdysone induced protein 78C 0.0039 0.0302 0.0302
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.028 0.0912
Trypanosoma brucei Metacaspase-4 0.0027 0.0178 0.0564
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0094 0.0094
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1044 0.3532
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0041 0.0041
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.1339 0.4543
Schistosoma mansoni hypothetical protein 0.0016 0.0067 0.0092
Brugia malayi Nuclear hormone receptor E75 0.0018 0.0094 0.0297
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0014 0.0032
Brugia malayi photoreceptor-specific nuclear receptor 0.0039 0.0302 0.0951
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0191 0.0601
Schistosoma mansoni brg-1 associated factor 0.0042 0.0335 0.0486
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0039 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0094 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0039 0.0302 0.0951
Brugia malayi bZIP transcription factor family protein 0.0089 0.0809 0.255
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0061 0.0192
Toxoplasma gondii ImpB/MucB/SamB family protein 0.001 0.0014 0.008
Trypanosoma brucei metacaspase MCA3 0.0027 0.0178 0.0564
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0121 0.0121
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.0247 0.0712
Schistosoma mansoni peroxidasin 0.0028 0.0191 0.0273
Schistosoma mansoni nuclear receptor 0.0018 0.0094 0.0132
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0075 0.0242
Loa Loa (eye worm) hypothetical protein 0.004 0.0312 0.0985
Leishmania major hypothetical protein, conserved 0.004 0.0312 0.1023
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0334 0.1097
Trichomonas vaginalis ran, putative 0.0021 0.0121 0.0456
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0075 0.2051
Trypanosoma cruzi metacaspase, putative 0.0027 0.0178 0.0594
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0312 0.0985
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0089 0.0809 0.0809
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0218 0.0218
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0075 0.0604
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0096 0.0096
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0121 0.0383
Leishmania major hypothetical protein, conserved 0.0025 0.0161 0.0505
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0312 0.0985
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0408 0.1286
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0312 0.0983
Brugia malayi nuclear receptor RXR 0.0021 0.0116 0.0367
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0132 0.1239 0.1813
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0335 0.1385
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0513 0.3357
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0218 0.0314
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0027 0.0178 0.0255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0039 0.0302 0.0951
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Plasmodium falciparum small ubiquitin-related modifier 0.003 0.0216 0.5391
Loa Loa (eye worm) hypothetical protein 0.0028 0.0191 0.0601
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0191 0.0601
Leishmania major hypothetical protein, conserved 0.0015 0.0061 0.016
Echinococcus multilocularis pyruvate kinase 0.0017 0.008 0.008
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0042 0.0335 0.1057
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.1003 0.8616
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0243 0.6238
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0191 0.0601
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.003 0.0216 0.0311
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0039 0.0302 0.0302
Schistosoma mansoni TRABID protein (C64 family) 0.0015 0.0061 0.0082
Echinococcus granulosus geminin 0.0348 0.342 0.342
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.1176 1
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0067 0.0211
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0121 0.0998
Brugia malayi Cell death protein 3 precursor 0.0027 0.0178 0.0562
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0075 0.0242
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0491 0.0491
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0052
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.1176 0.3982
Echinococcus multilocularis muscleblind protein 1 0.015 0.1425 0.1425
Schistosoma mansoni hypothetical protein 0.0042 0.0335 0.0486
Schistosoma mansoni microtubule-associated protein tau 0.0685 0.6814 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0951
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0067 0.0211
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0096 0.0304
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0302 0.0302
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0312 0.1023
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0132 0.1239 0.42
Echinococcus multilocularis muscleblind protein 0.015 0.1425 0.1425
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0039 0.0302 0.0951
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0951
Mycobacterium tuberculosis Probable reductase 0.0109 0.1003 0.3851
Entamoeba histolytica ubiquitin like protein 0.003 0.0216 0.1737
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0121 0.3107
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0039 0.0302 0.0302
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0015 0.0061 0.1246
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0034 0.0247 0.0779
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0313 0.1025
Brugia malayi hypothetical protein 0.0025 0.0161 0.0508
Loa Loa (eye worm) hypothetical protein 0.0015 0.0061 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0703
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0191 0.0822
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0027 0.0178 0.1484
Onchocerca volvulus Chorion peroxidase homolog 0.0028 0.0191 0.0822
Trypanosoma cruzi metacaspase, putative 0.0027 0.0178 0.0594
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.1003 0.3851
Trypanosoma cruzi small ubiquitin protein, putative 0.003 0.0216 0.0723
Leishmania major importin beta-1 subunit, putative 0.0023 0.0143 0.0442
Loa Loa (eye worm) hypothetical protein 0.0018 0.0094 0.0297
Echinococcus granulosus caspase 8 0.0027 0.0178 0.0178
Brugia malayi nuclear hormone receptor 0.0018 0.0094 0.0297
Brugia malayi hypothetical protein 0.0011 0.0016 0.0052
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1176 0.7812
Brugia malayi Thioredoxin reductase 0.0048 0.0389 0.1226
Echinococcus granulosus pyruvate kinase 0.0017 0.008 0.008
Trypanosoma brucei metacaspase 0.0027 0.0178 0.0564
Schistosoma mansoni cpg binding protein 0.0029 0.0196 0.0282
Brugia malayi Cytochrome P450 family protein 0.0017 0.0077 0.0242
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0513 0.1711
Echinococcus granulosus caspase 0.01 0.0916 0.0916
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0075 0.0604
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0096 0.0784
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0513 0.1711
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0039 0.0302 0.0436
Echinococcus granulosus ring and YY1 binding protein 0.0015 0.0061 0.0061
Chlamydia trachomatis DNA topoisomerase I 0.0042 0.0335 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.0094 0.0094
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0132 0.1239 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0132 0.1239 0.1239
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0061 0.0192
Echinococcus multilocularis pyruvate kinase 0.0033 0.0243 0.0243
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0077 0.0242
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0121 0.3593
Echinococcus granulosus caspase 3 0.0073 0.0647 0.0647
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.008 0.2049
Leishmania major GTP-binding protein, putative 0.0021 0.0121 0.0368
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0116 0.0367
Brugia malayi ecdysteroid receptor 0.0039 0.0302 0.0951
Loa Loa (eye worm) glutathione reductase 0.0048 0.0389 0.1226
Trypanosoma cruzi metacaspase 5, putative 0.0027 0.0178 0.0594
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0061 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0216 0.0867
Echinococcus multilocularis caspase 8 0.0027 0.0178 0.0178
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0312 0.0983
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0178 0.0703
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.1003 0.3851
Echinococcus granulosus FTZ F1 alpha 0.0039 0.0302 0.0302
Echinococcus granulosus caspase 2 0.0027 0.0178 0.0178
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0034 0.0247 0.0247
Brugia malayi conserved hypotetical protein 0.0018 0.0094 0.0297
Schistosoma mansoni hypothetical protein 0.0406 0.4002 0.587
Loa Loa (eye worm) nuclear hormone receptor 0.0018 0.0094 0.0297
Brugia malayi nuclear receptor NHR-88 0.0018 0.0094 0.0297
Schistosoma mansoni DNA helicase recq5 0.0019 0.0096 0.0135
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0042 0.0335 0.8572
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0335 0.0335
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.1125 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0027 0.0178 0.0703
Loa Loa (eye worm) hypothetical protein 0.0039 0.0302 0.0951
Schistosoma mansoni zinc finger protein 0.0015 0.0061 0.0082

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Reversal of hydrogen peroxide-induced LDH activity in human HUVE12 cells ChEMBL. 18068980

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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