Detailed information for compound 573482

Basic information

Technical information
  • TDR Targets ID: 573482
  • Name: Prestwick_557
  • MW: 400.264 | Formula: C17H22BrNO5
  • H donors: 1 H acceptors: 3 LogP: 1.73 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H](c1ccccc1)C(=O)OC1C[C@@H]2[C@@H]3[C@H]([C@H](C1)[N+]2([O-])C)O3.Br
  • InChi: 1S/C17H21NO5.BrH/c1-18(21)13-7-11(8-14(18)16-15(13)23-16)22-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11?,12-,13-,14+,15-,16+,18?;/m1./s1
  • InChiKey: MGNNYKWRWHQLCR-RDYQINQZSA-N  

Network

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Synonyms

  • Scopolamin-N-oxide hydrobromide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis sex peptide receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Schistosoma mansoni glutaminase 0.0636 0.2016 0.2016
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0226 0.0836
Brugia malayi follicle stimulating hormone receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0084 0.0221 0.0221
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0059 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0019
Loa Loa (eye worm) hypothetical protein 0.0119 0.0336 0.0409
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0335 0.0407
Schistosoma mansoni survival motor neuron protein 0.0106 0.0292 0.0292
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0052 0.5
Onchocerca volvulus 0.0106 0.0292 0.0742
Echinococcus multilocularis tumor protein p63 0.0337 0.1044 0.1044
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Plasmodium falciparum thioredoxin reductase 0.0038 0.007 0.3284
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Brugia malayi nuclear receptor RXR 0.0018 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Loa Loa (eye worm) inositol-1 0.0043 0.0086 0.0105
Echinococcus multilocularis muscleblind protein 0.0489 0.1537 0.1537
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0086 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.0059 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Schistosoma mansoni lamin 0.0122 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0002 0.0002
Brugia malayi phosphofructokinase 0.0119 0.0335 0.0407
Echinococcus granulosus mothers against decapentaplegic 5 0.0035 0.006 0.006
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.0059 0.0072
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0072 0.0012
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0335 0.0335
Echinococcus granulosus serotonin receptor 0.0022 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0045 0.0048
Brugia malayi hypothetical protein 0.0425 0.1331 0.1619
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0018 0.0018
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Echinococcus granulosus hypothetical protein 0.0022 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0072 0.17
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.035 0.1087 0.1321
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Brugia malayi hypothetical protein 0.035 0.1087 0.1321
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) RNA binding protein 0.0063 0.0153 0.0186
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0018 0.0018
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0084 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0226 0.0836
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.0059 0.0072
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.007 0.0177 0.0177
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0018 0.0018
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0012
Schistosoma mansoni myosin xvIII 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0047 0.0101 0.0123
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0034 0.0059 0.0059
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.0059 0.015
Loa Loa (eye worm) latrophilin receptor protein 2 0.007 0.0177 0.0215
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0774 0.2465 0.2465
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Onchocerca volvulus 0.0022 0.0018 0.0046
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0052 0.0937
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0059 0.0072
Brugia malayi G protein-coupled receptor 0.0022 0.0018 0.0021
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0018 0.0018
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0071 0.0071
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.0059 0.0072
Onchocerca volvulus 0.0022 0.0018 0.0045
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.004 0.0077 0.4137
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0221 0.0488
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0059 0.0138 0.0138
Brugia malayi Inositol-1 0.0043 0.0086 0.0105
Brugia malayi MH1 domain containing protein 0.0035 0.006 0.0073
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0013 0.0013
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0086 0.1875
Loa Loa (eye worm) hypothetical protein 0.0122 0.0343 0.0418
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Onchocerca volvulus 0.0061 0.0147 0.0374
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0018 0.0018
Brugia malayi intermediate filament protein 0.0122 0.0343 0.0418
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0072 0.0115
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0106 0.0292 0.0355
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0072 0.0012
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0108 0.0108
Echinococcus granulosus muscleblind protein 0.0489 0.1537 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0034 0.0019
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.0059 0.0059
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0122 0.0343 0.0418
Schistosoma mansoni prolyl 4-hydroxylase alpha subunit 1 0.0022 0.0018 0.0018
Echinococcus granulosus lamin dm0 0.0122 0.0343 0.0343
Brugia malayi MH1 domain containing protein 0.0035 0.006 0.0073
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.0127
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0018 0.0045
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0018 0.0018
Echinococcus multilocularis cpg binding protein 0.0067 0.0165 0.0165
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0076 0.1839
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Schistosoma mansoni bromodomain containing protein 0.0066 0.0162 0.0162
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Schistosoma mansoni histamine h1 receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.0059 0.0072
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0152 0.0443 0.0539
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0052 0.1193
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0072 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.0059 0.0072
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0055 0.0126 0.0126
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0018 0.0018
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0072 0.1954
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0018 0.0021
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0381 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0221 0.0221
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0335 0.0407
Echinococcus multilocularis geminin 0.0774 0.2465 0.2465
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.024 0.0728 0.0885
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Trichomonas vaginalis glutaminase, putative 0.0636 0.2016 0.4972
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus allatostatin A receptor 0.0022 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.0059 0.0059
Onchocerca volvulus 0.0022 0.0018 0.0045
Onchocerca volvulus 0.035 0.1087 0.2761
Schistosoma mansoni inositol monophosphatase 0.0043 0.0086 0.0086
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0728 0.0728
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Schistosoma mansoni hypothetical protein 0.0152 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0076 0.0125
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0055 0.0126 0.3404
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0381 0.1666
Brugia malayi N-terminal motif family protein 0.0179 0.053 0.0645
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0052 0.1193
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0052 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0223 0.0672 0.0817
Toxoplasma gondii isocitrate dehydrogenase 0.0055 0.0126 0.2968
Schistosoma mansoni hypothetical protein 0.0469 0.1472 0.1472
Brugia malayi hypothetical protein 0.0037 0.0069 0.0084
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0153 0.0186
Brugia malayi Latrophilin receptor protein 2 0.007 0.0177 0.0215
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.004 0.0077 0.0062
Trichomonas vaginalis esterase, putative 0.0038 0.0072 0.0114
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0018 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Brugia malayi GnHR receptor homolog 0.0022 0.0018 0.0021
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0335 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0018 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0018 0.0021
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0335 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0381 0.0381
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.0059 0.015
Echinococcus multilocularis thyroid hormone receptor alpha 0.0034 0.0059 0.0059
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.007 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Brugia malayi Pre-SET motif family protein 0.003 0.0046 0.0056
Brugia malayi Dopamine receptor protein 1 0.0022 0.0018 0.0021
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0076 0.0093
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0063 0.0063
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0613 0.1941 1
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0335 0.0335
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni hypothetical protein 0.0332 0.1029 0.1029
Schistosoma mansoni hypothetical protein 0.0037 0.0069 0.0069
Brugia malayi neuropeptide F receptor 0.0022 0.0018 0.0021
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0031 0.0031
Echinococcus multilocularis neuropeptide s receptor 0.1618 0.5213 0.5213
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0072 0.0012
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0018 0.0021
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.0059 0.0059
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.3607
Brugia malayi 6-phosphofructokinase 0.0119 0.0335 0.0407
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.0018 0.0021
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Echinococcus granulosus intermediate filament protein 0.0122 0.0343 0.0343
Brugia malayi hypothetical protein 0.0018 0.0006 0.0008
Loa Loa (eye worm) MH1 domain-containing protein 0.0035 0.006 0.0073
Echinococcus multilocularis lamin 0.0122 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0157 0.0458 0.0557
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0052 0.0937
Echinococcus granulosus tar DNA binding protein 0.0063 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.2543 0.8222 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0072 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.0059 0.0059
Brugia malayi beta-lactamase 0.0038 0.0072 0.0087
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0055 0.0126 0.0126
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0072 0.0114
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0072 0.0012
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.004 0.0077 0.1616
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0071 0.0071
Brugia malayi Calcitonin receptor-like protein seb-1 0.0223 0.0672 0.0817
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.0742 0.3596
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0055 0.0126 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0046 0.0046
Treponema pallidum fructose-bisphosphate aldolase 0.1254 0.4028 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0063 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0223 0.0672 0.0817
Brugia malayi latrophilin 2 splice variant baaae 0.0152 0.0443 0.0539
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2391
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0381 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Echinococcus multilocularis ubiquitin specific protease 41 0.0084 0.0221 0.0221
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.0257 0.1003
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.0059 0.0059
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi prolyl 4-hydroxylase 0.0022 0.0018 0.0022
Mycobacterium leprae Probable lipase LipE 0.0038 0.0072 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Echinococcus multilocularis neuropeptide receptor A26 0.1618 0.5213 0.5213
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Echinococcus granulosus TGF beta signal transducer SmadC 0.0035 0.006 0.006
Plasmodium falciparum glutathione reductase 0.0038 0.007 0.3284
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0226 0.0836
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Loa Loa (eye worm) hypothetical protein 0.0489 0.1537 0.187
Onchocerca volvulus 0.0022 0.0018 0.0045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0381 0.1592
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0018 0.0021
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0221 0.5597
Schistosoma mansoni biogenic amine (5HT) receptor 0.0157 0.0458 0.0458
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.007 0.3284
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.1854
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0086 0.015
Trypanosoma brucei 2OG-Fe(II) oxygenase superfamily, putative 0.0022 0.0018 0.0307
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0072 0.0011
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2151
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0226 0.0836
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0055 0.0126 1
Echinococcus multilocularis survival motor neuron protein 1 0.0519 0.1637 0.1637
Echinococcus multilocularis X box binding protein 1 0.0332 0.1029 0.1029
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0018 0.0018
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0076 0.1603
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi Bromodomain containing protein 0.0078 0.02 0.0243
Loa Loa (eye worm) hypothetical protein 0.0038 0.0071 0.0086
Onchocerca volvulus 0.1225 0.3935 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0018 0.0018
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.0257 0.1003
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) prolyl 4-hydroxylase 2 0.0022 0.0018 0.0022
Brugia malayi hypothetical protein 0.0019 0.0008 0.001
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0052 0.1193
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0381 0.0381
Brugia malayi Intermediate filament tail domain containing protein 0.0122 0.0343 0.0418
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis dnaJ subfamily B 0.0469 0.1472 0.1472
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0042 0.1043
Brugia malayi putative neuropeptide receptor 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0059 0.0138 0.0168
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0335 0.0335
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0018 0.0018
Brugia malayi ORL1-like opioid receptor 0.0022 0.0018 0.0021
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.2151
Echinococcus multilocularis smad 0.0035 0.006 0.006
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.0059 0.0059
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0042 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0093 0.2071
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi steroid hormone receptor 0.0034 0.0059 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0018 0.0021
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi nuclear receptor NHR-88 0.0034 0.0059 0.0072
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0072 0.0072
Echinococcus multilocularis isocitrate dehydrogenase 0.0055 0.0126 0.0126
Mycobacterium tuberculosis Conserved protein 0.0038 0.0072 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0093 0.2375
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.0059 0.0072
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.004 0.0077 0.0077
Echinococcus multilocularis muscleblind protein 1 0.0489 0.1537 0.1537
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0018 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.0059 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0076 0.1839
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.007 0.0177 0.0177
Schistosoma mansoni cpg binding protein 0.0067 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi neuropeptide F receptor 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0086 0.5
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0093 0.0093
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.002 0.0014 0.0014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.007 0.0177 0.0215
Trypanosoma brucei glucosidase, putative 0.004 0.0076 0.2089
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0031 0.0031
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0101 0.0101
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0002
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0052 0.5
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.004 0.0077 0.0077
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0035 0.006 0.006
Schistosoma mansoni adenoreceptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.0528 0.0642
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0337 0.8781
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0728 0.0728
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0018 0.0018
Brugia malayi Thioredoxin reductase 0.0038 0.007 0.0085
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0221 0.0488
Schistosoma mansoni cpg binding protein 0.0067 0.0165 0.0165
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.0127
Loa Loa (eye worm) hypothetical protein 0.0049 0.0108 0.0131
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0221 0.0221
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1254 0.4028 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.0257 0.0993
Echinococcus granulosus lamin 0.0122 0.0343 0.0343
Echinococcus granulosus survival motor neuron protein 1 0.0519 0.1637 0.1637
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.0059 0.0059
Schistosoma mansoni alpha-glucosidase 0.0154 0.0447 0.0447
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0069 0.0069
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0018 0.0021
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0035 0.006 0.006
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0018 0.0021
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0018 0.0021
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0093 0.2609
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0018 0.0018
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.0059 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi 6-phosphofructokinase 0.0119 0.0335 0.0407
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0018 0.0018
Echinococcus multilocularis mothers against decapentaplegic 5 0.0035 0.006 0.006
Schistosoma mansoni lamin 0.0122 0.0343 0.0343
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0018 0.0018
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0059 0.0059
Brugia malayi Dopamine receptor 0.0022 0.0018 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0221 0.0221
Brugia malayi MH2 domain containing protein 0.0507 0.1598 0.1943
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0052 0.0937
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0072 0.0072
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0086 0.0086
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0063 0.1437
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0018 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0093 0.2071
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1254 0.4028 1
Brugia malayi MH2 domain containing protein 0.0035 0.006 0.0073
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0093 0.2375
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0086 0.0086
Schistosoma mansoni microtubule-associated protein tau 0.3089 1 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0093 0.0093
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.0059 0.0059
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0063 0.17
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.0059 0.015
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0084 0.0221 0.0426
Echinococcus multilocularis lamin dm0 0.0122 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0052 0.1193
Brugia malayi RNA binding protein 0.0063 0.0153 0.0186
Trypanosoma brucei trypanothione reductase 0.0038 0.007 0.1885
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0069 0.0069
Echinococcus granulosus FTZ F1 alpha 0.0034 0.0059 0.0059
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.007 0.1628
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0335 0.0771
Echinococcus granulosus neuropeptide s receptor 0.1618 0.5213 0.5213
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0018 0.0021
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Brugia malayi larval opioid receptor 0.0022 0.0018 0.0021
Giardia lamblia Fructose-bisphosphate aldolase 0.1254 0.4028 1
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0381 0.0381
Loa Loa (eye worm) transcription factor SMAD2 0.0507 0.1598 0.1943
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.0257 0.1003
Mycobacterium tuberculosis Probable reductase 0.0086 0.0226 0.0836
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.007 0.0177 0.0177
Schistosoma mansoni intermediate filament proteins 0.0122 0.0343 0.0343
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.0059 0.0059
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0034 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Plasmodium vivax glutathione reductase, putative 0.0038 0.007 0.3284
Loa Loa (eye worm) hypothetical protein 0.0425 0.1331 0.1619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0034 0.0059 0.0059
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi ecdysteroid receptor 0.0034 0.0059 0.0072
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0076 0.0061
Loa Loa (eye worm) Smad1 0.0035 0.006 0.0073
Brugia malayi hypothetical protein 0.0519 0.1637 0.1991
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0034 0.0059 0.0059
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6419
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.0059 0.0072
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0093 0.0104
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0072 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.007 0.0177 0.0177
Brugia malayi sulfakinin receptor protein 0.0022 0.0018 0.0021
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0004 0.0005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0055 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0038 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.0116
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Schistosoma mansoni amine GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0042 0.0662
Brugia malayi Dopamine receptor protein 2 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus granulosus sex peptide receptor 0.0022 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.0059 0.0072
Loa Loa (eye worm) MH2 domain-containing protein 0.0035 0.006 0.0073
Plasmodium vivax SET domain protein, putative 0.003 0.0046 0.0477
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0122 0.0343 0.0873
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0072 0.0087
Brugia malayi beta-lactamase family protein 0.0038 0.0072 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0059 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi Pre-SET motif family protein 0.0203 0.0609 0.0741
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0076 0.0125
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6419
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0519 0.1637 0.1991
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0018 0.0045
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0226 0.0827
Toxoplasma gondii ABC1 family protein 0.0038 0.0072 0.1482
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.3404
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0076 0.0093
Brugia malayi G-protein coupled receptor 0.0022 0.0018 0.0021
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0042 0.0759
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0072 0.0087
Schistosoma mansoni retinoic acid receptor RXR 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0031 0.0031
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0056 0.1042
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0223 0.0672 0.0817
Brugia malayi MH1 domain containing protein 0.0019 0.001 0.0012
Toxoplasma gondii thioredoxin reductase 0.0038 0.007 0.142
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0059 0.0059
Loa Loa (eye worm) glutaminase 2 0.0636 0.2016 0.2452
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0018 0.0018
Schistosoma mansoni alpha glucosidase 0.004 0.0076 0.0076
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.004 0.0077 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0072 0.3555
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Onchocerca volvulus 0.003 0.0046 0.0117
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus granulosus geminin 0.0774 0.2465 0.2465
Echinococcus granulosus neuropeptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0335 0.8719
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Brugia malayi hypothetical protein 0.0018 0.0006 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0018 0.0018
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.004 0.0077 0.1616
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0335 0.1352
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Onchocerca volvulus 0.0038 0.0072 0.0183
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Leishmania major hypothetical protein, conserved 0.0029 0.0042 0.0662
Echinococcus multilocularis zinc finger protein 0.0023 0.0022 0.0022
Onchocerca volvulus 0.0022 0.0018 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Leishmania major hypothetical protein, conserved 0.0038 0.0072 0.1482
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.0059 0.0072
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis serotonin receptor 0.0157 0.0458 0.0458
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0018 0.0021
Echinococcus granulosus neuropeptide receptor A26 0.1618 0.5213 0.5213
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Schistosoma mansoni opsin-like receptor 0.0022 0.0018 0.0018
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0076 0.1603
Echinococcus multilocularis musashi 0.0122 0.0343 0.0343
Onchocerca volvulus 0.0034 0.0059 0.015
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0018 0.0021
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0101 0.0101
Echinococcus granulosus biogenic amine 5HT receptor 0.0157 0.0458 0.0458
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis Smad4 0.0035 0.006 0.006
Onchocerca volvulus 0.0049 0.0108 0.0274
Echinococcus granulosus Smad4 0.0035 0.006 0.006
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0018 0.0018
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0006 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0122 0.0343 0.0873
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0018 0.0018
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0093 0.0104
Brugia malayi AKH receptor 0.0022 0.0018 0.0021
Brugia malayi PHD-finger family protein 0.0028 0.0039 0.0047
Loa Loa (eye worm) MH2 domain-containing protein 0.0507 0.1598 0.1943
Loa Loa (eye worm) hypothetical protein 0.2543 0.8222 1
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0381 0.0381
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0018 0.0018
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0335 0.0407
Brugia malayi Serotonin receptor 0.0022 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.0059 0.0072
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.015 0.015
Echinococcus granulosus fmrfamide receptor 0.0022 0.0018 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0059 0.0059
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0221 0.0221
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0018 0.0018
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0018 0.0018
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi Muscleblind-like protein 0.0489 0.1537 0.187
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0018 0.0018
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.015 0.015
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0221 0.6529
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Echinococcus granulosus smad 0.0035 0.006 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0093 0.0168
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.0059 0.0059
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi cytoplasmic intermediate filament protein 0.0065 0.016 0.0194
Loa Loa (eye worm) hypothetical protein 0.0489 0.1537 0.187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus neuropeptide receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0157 0.0458 0.0557
Schistosoma mansoni inositol monophosphatase 0.0043 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Onchocerca volvulus Huntingtin homolog 0.0425 0.1331 0.3383
Schistosoma mansoni alpha-glucosidase 0.0154 0.0447 0.0447
Loa Loa (eye worm) histone methyltransferase 0.002 0.0013 0.0015
Schistosoma mansoni hypothetical protein 0.0106 0.0292 0.0292
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0084 0.0221 0.0426
Echinococcus granulosus orexin receptor type 2 0.0022 0.0018 0.0018
Echinococcus granulosus zinc finger protein 0.0023 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0063 0.0093
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.0077 0.1854
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0093 0.0113
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0076 0.0125
Echinococcus granulosus tumor protein p63 0.0337 0.1044 0.1044
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0076 0.0076
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0929 0.297 0.297
Loa Loa (eye worm) isocitrate dehydrogenase 0.0055 0.0126 0.0153
Brugia malayi Isocitrate dehydrogenase 0.0055 0.0126 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0059 0.0072
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0006 0.0008
Leishmania major trypanothione reductase 0.0038 0.007 0.142
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0018 0.0021
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0076 0.0125
Schistosoma mansoni biogenic amine receptor 0.0022 0.0018 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.0059 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0059 0.0072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Onchocerca volvulus 0.0038 0.0072 0.0183
Brugia malayi beta-lactamase family protein 0.0038 0.0072 0.0087
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0728 0.0728
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.004 0.0077 0.0093
Brugia malayi CXXC zinc finger family protein 0.0061 0.0147 0.0179
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0335 0.1417
Loa Loa (eye worm) beta-lactamase 0.0038 0.0072 0.0087
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi nuclear hormone receptor 0.0034 0.0059 0.0072
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0086 0.015
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.0528 0.0528
Brugia malayi Smad1 0.0035 0.006 0.0073
Onchocerca volvulus Huntingtin homolog 0.0425 0.1331 0.3383
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0375 0.0375
Echinococcus granulosus prolyl 4 hydroxylase subunit alpha 1 0.0022 0.0018 0.0018
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0076 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0221 0.0488
Echinococcus multilocularis prolyl 4 hydroxylase subunit alpha 1 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0056 0.0131 0.016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0046 0.0772
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Giardia lamblia GTOR 0.0045 0.0093 0.0104
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.0059 0.0059
Trichomonas vaginalis set domain proteins, putative 0.0231 0.07 0.1684
Loa Loa (eye worm) glutathione reductase 0.0038 0.007 0.0085
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Brugia malayi MH2 domain containing protein 0.0035 0.006 0.0073
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0093 0.0093
Echinococcus multilocularis serotonin receptor 0.0157 0.0458 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0076 0.0125
Onchocerca volvulus 0.0038 0.0072 0.0183
Schistosoma mansoni cpg binding protein 0.0061 0.0147 0.0147
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0069 0.0069
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0018 0.0018
Echinococcus granulosus cpg binding protein 0.0067 0.0165 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0035 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0072 0.17
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0728 0.0728
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni neuropeptide receptor 0.0022 0.0018 0.0018
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0084 0.0221 0.0269
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0101 0.0101
Brugia malayi TAR-binding protein 0.0063 0.0153 0.0186
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.0087
Loa Loa (eye worm) hypothetical protein 0.0179 0.053 0.0645
Loa Loa (eye worm) nuclear factor I 0.0019 0.001 0.0012
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0093 0.2609
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0055 0.0126 0.0301
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0014 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Mycobacterium ulcerans glutaminase 0.0636 0.2016 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Echinococcus granulosus somatostatin receptor 0.0022 0.0018 0.0018
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.0528 0.0642
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0059 0.0138 0.0138
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.053 0.1348
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.024 0.0728 0.0885
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0008
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0065 0.016 0.0194
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0018 0.0018
Schistosoma mansoni zinc finger protein 0.0023 0.0022 0.0022
Toxoplasma gondii isocitrate dehydrogenase 0.0055 0.0126 0.2968
Trypanosoma brucei ubiquitin-protein ligase, putative 0.004 0.0077 0.2103
Echinococcus multilocularis somatostatin receptor 0.0022 0.0018 0.0018
Brugia malayi Serotonin receptor 0.0022 0.0018 0.0021
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0072 0.0012
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0016 0.0257
Echinococcus granulosus dnaJ subfamily B 0.0469 0.1472 0.1472
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0072 0.0072
Brugia malayi Bromodomain containing protein 0.0038 0.007 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0037 0.0069 0.0044
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.0059 0.0059
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0018 0.0018
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0063 0.1253
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0006 0.0006
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0613 0.1941 1
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Echinococcus granulosus ubiquitin specific protease 41 0.0084 0.0221 0.0221
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0335 0.1408
Brugia malayi glutaminase DH11.1 0.0636 0.2016 0.2452
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0153 0.0153
Onchocerca volvulus 0.0022 0.0018 0.0045
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0093 0.0113
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0018 0.0018
Echinococcus multilocularis microtubule associated protein 2 0.3089 1 1
Onchocerca volvulus 0.0022 0.0018 0.0045
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0018 0.0018
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0059 0.0059
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0728 0.0728
Onchocerca volvulus 0.0231 0.07 0.1779
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0018 0.0018
Loa Loa (eye worm) intermediate filament protein 0.0122 0.0343 0.0418
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0153 0.0186
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.0059 0.0072
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.0059 0.0059
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0072 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0147 0.0179
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0018 0.0018
Schistosoma mansoni Smad4 0.0035 0.006 0.006
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0335 0.0711
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Echinococcus multilocularis GPCR, family 2 0.007 0.0177 0.0177
Schistosoma mansoni hypothetical protein 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0072 0.0012
Schistosoma mansoni smad 0.0035 0.006 0.006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.0059 0.0072
Brugia malayi hypothetical protein 0.0029 0.0042 0.0051
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.004 0.0077 0.4137
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1254 0.4028 1
Echinococcus granulosus g protein coupled receptor 0.0022 0.0018 0.0018
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0084 0.0221 0.0269
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0086 0.1875
Echinococcus multilocularis FTZ F1 alpha 0.0034 0.0059 0.0059
Brugia malayi Melatonin receptor type 1A 0.0022 0.0018 0.0021
Schistosoma mansoni coup transcription factor 0.0034 0.0059 0.0059
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0018 0.0021
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0042 0.0759
Echinococcus granulosus X box binding protein 1 0.0332 0.1029 0.1029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0022
Brugia malayi G-protein coupled receptor 0.0022 0.0018 0.0021
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0056 0.0131 0.016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0056 0.0075
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0072 0.0114
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0153 0.0186
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi RE15519p 0.0022 0.0018 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0153 0.0153
Schistosoma mansoni smad1 5 8 and 0.0035 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.0059 0.0072
Loa Loa (eye worm) glutaminase 0.0636 0.2016 0.2452
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0613 0.1941 0.9614
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0335 0.0711
Loa Loa (eye worm) hypothetical protein 0.0034 0.0059 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0059 0.0072
Loa Loa (eye worm) hypothetical protein 0.004 0.0078 0.0095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0018 0.0018
Brugia malayi hypothetical protein 0.0022 0.0018 0.0021
Schistosoma mansoni hypothetical protein 0.007 0.0177 0.0177
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0226 0.0836
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0052 0.0065
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0055 0.0126 0.3607
Loa Loa (eye worm) hypothetical protein 0.0425 0.1331 0.1619
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0086 0.015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0021
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0055 0.0126 0.2968
Schistosoma mansoni hypothetical protein 0.0774 0.2465 0.2465
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.0609 0.0741
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0006 0.0006
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0018 0.0021
Brugia malayi isocitrate dehydrogenase 0.0055 0.0126 0.0153
Loa Loa (eye worm) hypothetical protein 0.007 0.0177 0.0215
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0046 0.0046
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0018 0.0018
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0076 0.0061
Echinococcus granulosus GPCR family 2 0.007 0.0177 0.0177
Brugia malayi glutathione reductase 0.0038 0.007 0.0085
Onchocerca volvulus 0.0103 0.0283 0.072

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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