Detailed information for compound 57696

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 272.302 | Formula: C14H16N4O2
  • H donors: 1 H acceptors: 3 LogP: 2.25 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1NCCN(C1)c1ccc2c(n1)ccc(c2)[N+](=O)[O-]
  • InChi: 1S/C14H16N4O2/c1-10-9-17(7-6-15-10)14-5-2-11-8-12(18(19)20)3-4-13(11)16-14/h2-5,8,10,15H,6-7,9H2,1H3
  • InChiKey: WIRIBEHWECMIRC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Serotonin transporter Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis sodium and chloride dependent glycine Serotonin transporter   630 aa 617 aa 39.4 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 582 aa 35.2 %
Drosophila melanogaster CG1698 gene product from transcript CG1698-RA Serotonin transporter   630 aa 585 aa 34.2 %
Onchocerca volvulus Serotonin transporter   630 aa 611 aa 26.4 %
Schistosoma mansoni sodium/chloride dependent transporter Serotonin transporter   630 aa 605 aa 37.7 %
Schistosoma japonicum ko:K05046 solute carrier family 6 (neurotransmitter transporter, GABA), member, putative Serotonin transporter   630 aa 581 aa 40.1 %
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 576 aa 31.8 %
Echinococcus granulosus sodium and chloride dependent glycine Serotonin transporter   630 aa 617 aa 39.4 %
Toxoplasma gondii Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 509 aa 28.3 %
Plasmodium knowlesi transporter, putative Serotonin transporter   630 aa 514 aa 20.2 %
Drosophila melanogaster CG13796 gene product from transcript CG13796-RD Serotonin transporter   630 aa 638 aa 25.1 %
Brugia malayi Sodium:neurotransmitter symporter family protein Serotonin transporter   630 aa 576 aa 30.9 %
Schistosoma mansoni sodium/chloride dependent transporter Serotonin transporter   630 aa 552 aa 41.5 %
Schistosoma japonicum ko:K05042 solute carrier family 6 (neurotransmitter transporter, glycine),, putative Serotonin transporter   630 aa 520 aa 36.2 %
Onchocerca volvulus High affinity copper uptake protein 1 homolog Serotonin transporter   630 aa 629 aa 47.1 %
Onchocerca volvulus Transmembrane protein 120 homolog Serotonin transporter   630 aa 571 aa 31.2 %
Plasmodium vivax hypothetical protein, conserved Serotonin transporter   630 aa 528 aa 21.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0074 0.0501
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0114 0.0362 0.2443
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0216 0.0542
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0073 0.0206 0.1006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0074 0.0187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0186 0.064 0.4312
Trichomonas vaginalis histone deacetylase, putative 0.0094 0.0286 0.1926
Schistosoma mansoni neuropeptide receptor 0.0045 0.0096 0.0096
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0045 0.0096 0.0096
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.015 0.1013
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0186 0.064 0.1213
Entamoeba histolytica hypothetical protein 0.0048 0.0108 0.0785
Brugia malayi Integrin beta pat-3 precursor 0.0708 0.2641 0.5008
Onchocerca volvulus 0.0186 0.064 0.4612
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0045 0.0096 0.0096
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0257 0.0911 0.1727
Plasmodium vivax importin-beta 2, putative 0.0059 0.015 0.0574
Schistosoma mansoni DNA polymerase eta 0.0039 0.0074 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Echinococcus granulosus 7TM GPCR rhodopsin 0.0045 0.0096 0.0096
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0186 0.064 0.064
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Schistosoma mansoni chromobox protein 0.0186 0.064 0.064
Toxoplasma gondii preprocathepsin c precursor, putative 0.0114 0.0362 0.2443
Schistosoma mansoni biogenic amine receptor 0.0045 0.0096 0.0096
Onchocerca volvulus 0.0045 0.0096 0.0596
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0108 0.0725
Brugia malayi Papain family cysteine protease containing protein 0.0114 0.0362 0.0687
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0073 0.0206 0.1389
Loa Loa (eye worm) hypothetical protein 0.0074 0.0209 0.0396
Schistosoma mansoni amine GPCR 0.0045 0.0096 0.0096
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0074 0.0074
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0377 0.137 1
Giardia lamblia Cathepsin L precursor 0.0114 0.0362 0.2443
Echinococcus granulosus prolyl endopeptidase 0.0128 0.0415 0.0415
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0186 0.064 0.4312
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0186 0.064 0.4312
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0128 0.0415 0.2796
Mycobacterium tuberculosis Probable peptidase 0.0051 0.012 0.0579
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0222 0.0556
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0096 0.0096
Brugia malayi cathepsin B-like cysteine proteinase 0.1059 0.3988 0.7562
Leishmania major histone deacetylase, putative 0.0077 0.0219 0.1477
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0154 0.0514 0.0514
Echinococcus granulosus histone deacetylase 7 0.0077 0.0219 0.0219
Plasmodium falciparum serine repeat antigen 3 0.0114 0.0362 0.2646
Schistosoma mansoni cathepsin F (C01 family) 0.0337 0.1218 0.1218
Echinococcus multilocularis glycoprotein Antigen 5 0.0025 0.0022 0.0022
Loa Loa (eye worm) glutamate receptor 1 0.0066 0.0176 0.0334
Entamoeba histolytica cysteine proteinase 2 0.0154 0.0514 0.3752
Onchocerca volvulus 0.0377 0.137 1
Echinococcus granulosus tissue type plasminogen activator 0.0053 0.0128 0.0128
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0186 0.064 0.4671
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1059 0.3988 0.3988
Trypanosoma cruzi histone deacetylase, putative 0.0077 0.0219 0.055
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0222 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Plasmodium vivax histone deacetylase, putative 0.0049 0.0111 0.0269
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0171 0.0579 0.0579
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0369 0.196
Onchocerca volvulus 0.0377 0.137 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.005 0.0095
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0074 0.0329
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0222 0.0556
Loa Loa (eye worm) hypothetical protein 0.0039 0.0076 0.0144
Loa Loa (eye worm) norepinephrine transporter 0.0073 0.0205 0.0388
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0911 0.6138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1027 0.6925
Entamoeba histolytica cysteine proteinase, putative 0.0154 0.0514 0.3752
Brugia malayi Calcitonin receptor-like protein seb-1 0.0245 0.0866 0.1642
Schistosoma mansoni hypothetical protein 0.0078 0.0222 0.0222
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0068 0.0187 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.015 0.1009
Schistosoma mansoni sex comb on midleg homolog 0.0096 0.0294 0.0294
Schistosoma mansoni growth hormone secretagogue receptor 0.0045 0.0096 0.0096
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Brugia malayi latrophilin 2 splice variant baaae 0.0168 0.0568 0.1077
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0074 0.0074
Brugia malayi AKH receptor 0.0045 0.0096 0.0181
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Onchocerca volvulus 0.0045 0.0096 0.0596
Echinococcus multilocularis histone deacetylase 6 0.0077 0.0219 0.0219
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0186 0.064 0.064
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0094 0.0286 0.1926
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0022 0.0022
Echinococcus multilocularis musashi 0.0026 0.0025 0.0025
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0186 0.064 0.1213
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0096 0.0096
Trypanosoma brucei prolyl endopeptidase 0.0128 0.0415 0.2796
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0222 0.1144
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Echinococcus granulosus alpha 1A adrenergic receptor 0.0045 0.0096 0.0096
Schistosoma mansoni myelin transcription factor 1 myt1 0.0109 0.0345 0.0345
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0045 0.0096 0.0096
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0114 0.0362 0.2646
Plasmodium falciparum histone deacetylase 2 0.0077 0.0219 0.16
Schistosoma mansoni opsin-like receptor 0.0045 0.0096 0.0096
Plasmodium falciparum serine repeat antigen 8 0.0114 0.0362 0.2646
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0377 0.137 0.2597
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0051 0.012 0.2334
Schistosoma mansoni chromobox protein 0.0186 0.064 0.064
Trypanosoma cruzi histone deacetylase 1, putative 0.0094 0.0286 0.0717
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0111 0.0351 0.0666
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0245 0.0866 0.1642
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0406 0.1484 1
Echinococcus multilocularis tissue type plasminogen activator 0.0053 0.0128 0.0128
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.007 0.0194 0.0194
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0222 0.042
Echinococcus multilocularis histone deacetylase 3 0.0094 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0714 0.2662 0.5049
Leishmania major hypothetical protein, conserved 0.0076 0.0216 0.1457
Echinococcus granulosus dro:myosuppressin receptor 0.0045 0.0096 0.0096
Trypanosoma cruzi histone deacetylase, putative 0.0049 0.0111 0.0278
Mycobacterium ulcerans beta-lactamase 0.0077 0.0222 0.4609
Echinococcus multilocularis cathepsin L cysteine protease 0.0377 0.137 0.137
Onchocerca volvulus 0.0049 0.0113 0.0724
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0096 0.0096
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0114 0.0362 0.2443
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Trypanosoma cruzi histone deacetylase, putative 0.0049 0.0111 0.0278
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0091 0.0091
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0222 0.1144
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0111 0.0351 0.0666
Onchocerca volvulus 0.0179 0.0612 0.441
Echinococcus multilocularis chromobox protein 2 0.2626 1 1
Brugia malayi histone deacetylase 3 (HD3) 0.0094 0.0286 0.0542
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0186 0.064 0.4312
Echinococcus multilocularis histone deacetylase 0.0077 0.0219 0.0219
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0114 0.0362 0.0362
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0036 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1027 0.6925
Loa Loa (eye worm) hypothetical protein 0.0077 0.0222 0.042
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0362 0.2443
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Schistosoma mansoni ran 0.0043 0.0091 0.0091
Brugia malayi Cathepsin L-like precursor 0.0337 0.1218 0.231
Entamoeba histolytica cysteine proteinase, putative 0.0154 0.0514 0.3752
Trypanosoma brucei trypanothione reductase 0.0046 0.01 0.0673
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0096 0.0096
Schistosoma mansoni hypothetical protein 0.0628 0.2333 0.2333
Plasmodium vivax unspecified product 0.0154 0.0514 0.3385
Schistosoma mansoni hypothetical protein 0.0045 0.0096 0.0096
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0055 0.0055
Schistosoma mansoni chromobox protein 0.0186 0.064 0.064
Echinococcus granulosus cathepsin b 0.1059 0.3988 0.3988
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0186 0.064 0.1213
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.0108 0.0205
Loa Loa (eye worm) hypothetical protein 0.0068 0.0187 0.0354
Brugia malayi beta-lactamase family protein 0.0077 0.0222 0.042
Echinococcus granulosus histone deacetylase 6 0.0083 0.0243 0.0243
Leishmania major histone deacetylase, putative 0.0094 0.0286 0.1926
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0477 0.0477
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trichomonas vaginalis histone deacetylase, putative 0.0094 0.0286 0.1926
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0216 0.0542
Leishmania major cathepsin L-like protease 0.0377 0.137 0.9231
Loa Loa (eye worm) serotonin transporter b 0.0073 0.0205 0.0388
Plasmodium falciparum serine repeat antigen 6 0.0114 0.0362 0.2646
Onchocerca volvulus 0.0377 0.137 1
Echinococcus multilocularis transient receptor potential gamma protein 0.0097 0.0295 0.0295
Echinococcus multilocularis prolyl endopeptidase 0.0128 0.0415 0.0415
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.017 0.017
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0911 0.6138
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Onchocerca volvulus Matrix metalloproteinase homolog 0.0104 0.0324 0.228
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0074 0.1327
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1027 0.6925
Onchocerca volvulus 0.0045 0.0096 0.0596
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0091 0.0611
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0154 0.0514 0.0514
Treponema pallidum exodeoxyribonuclease (exoA) 0.0073 0.0206 0.0018
Entamoeba histolytica hypothetical protein 0.0186 0.064 0.4671
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0114 0.0362 0.2443
Brugia malayi Papain family cysteine protease containing protein 0.0154 0.0514 0.0974
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0045 0.0096 0.0096
Brugia malayi cathepsin L-like cysteine proteinase 0.0114 0.0362 0.0687
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0606 0.4088
Loa Loa (eye worm) cathepsin B 0.0406 0.1484 0.2814
Loa Loa (eye worm) melatonin receptor type 1A 0.0045 0.0096 0.0181
Mycobacterium leprae PROBABLE HYDROLASE 0.0057 0.0144 0.2875
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0186 0.064 0.064
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0114 0.0362 0.2443
Schistosoma mansoni hypothetical protein 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0073 0.0205 0.0388
Echinococcus granulosus histone deacetylase 6 0.0077 0.0219 0.0219
Plasmodium vivax glutathione reductase, putative 0.0046 0.01 0.0184
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0096 0.0096
Schistosoma mansoni histone deacetylase 0.0094 0.0286 0.0286
Brugia malayi Kringle domain containing protein 0.0053 0.0128 0.0243
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0114 0.0362 0.2214
Echinococcus multilocularis serotonin transporter 0.0073 0.0205 0.0205
Brugia malayi Protein cec-1. 0.0186 0.064 0.1213
Echinococcus granulosus inhibitor of apoptosis protein 0.0054 0.0132 0.0132
Echinococcus multilocularis neuropeptide s receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis chromobox protein, putative 0.0186 0.064 0.4312
Onchocerca volvulus 0.0077 0.0222 0.1526
Leishmania major GTP-binding protein, putative 0.0043 0.0091 0.0611
Echinococcus granulosus enteropeptidase 0.0025 0.0022 0.0022
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.017 0.017
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0045 0.0096 0.0181
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.007 0.0194 0.0194
Loa Loa (eye worm) latrophilin receptor protein 2 0.0078 0.0222 0.0422
Trypanosoma cruzi histone deacetylase, putative 0.0077 0.0219 0.055
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0022 0.0022
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0054 0.0132 0.0132
Echinococcus granulosus integrin beta 2 0.0518 0.1913 0.1913
Schistosoma mansoni cathepsin s 0.0039 0.0076 0.0076
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0096 0.0096
Schistosoma mansoni histone deacetylase 4 5 0.0077 0.0219 0.0219
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0114 0.0362 0.0362
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Entamoeba histolytica cysteine proteinase 1, putative 0.0154 0.0514 0.3752
Giardia lamblia Histone deacetylase 0.0094 0.0286 0.1926
Brugia malayi G protein-coupled receptor 0.0045 0.0096 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0154 0.0514 0.3463
Plasmodium vivax serine-repeat antigen (SERA) 0.0114 0.0362 0.2214
Loa Loa (eye worm) hypothetical protein 0.0336 0.1213 0.23
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0096 0.0096
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0037 0.0067 0.045
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0025 0.0047
Schistosoma mansoni hypothetical protein 0.0053 0.0128 0.0128
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0245 0.0866 0.1642
Onchocerca volvulus 0.0045 0.0096 0.0596
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0222 0.1144
Giardia lamblia DINP protein human, muc B family 0.0039 0.0074 0.0501
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0222 0.042
Trypanosoma cruzi cysteine peptidase, putative 0.0154 0.0514 0.1289
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0073 0.0206 0.1389
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0073 0.0206 0.0517
Echinococcus multilocularis glutamate receptor 2 0.0066 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trypanosoma cruzi histone deacetylase 1, putative 0.0094 0.0286 0.0717
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0096 0.0096
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0073 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Onchocerca volvulus 0.0025 0.0022 0.0051
Schistosoma mansoni histone deacetylase hda2 0.0083 0.0243 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Onchocerca volvulus 0.0025 0.0022 0.0051
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0025 0.0047
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0054 0.0132 0.0251
Trichomonas vaginalis chromobox protein, putative 0.0186 0.064 0.4312
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0186 0.064 0.4612
Brugia malayi Muscleblind-like protein 0.0146 0.0486 0.0923
Echinococcus granulosus glutamate receptor 4 0.0041 0.0082 0.0082
Brugia malayi cathepsin F-like cysteine proteinase 0.0114 0.0362 0.0687
Echinococcus multilocularis transient receptor potential ion channel A 0.0093 0.0283 0.0283
Schistosoma mansoni adenoreceptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0078 0.0222 0.0422
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0477 0.0477
Echinococcus multilocularis histone deacetylase 6 0.0083 0.0243 0.0243
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0074 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0114 0.0362 0.0687
Loa Loa (eye worm) hypothetical protein 0.0168 0.0568 0.1077
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0028 0.0188
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0222 0.0222
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0074 0.0501
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Giardia lamblia Cathepsin B precursor 0.0114 0.0362 0.2443
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0186 0.064 0.1213
Onchocerca volvulus 0.0114 0.0362 0.2566
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0146 0.0486 0.0923
Brugia malayi Importin beta-1 subunit 0.0059 0.015 0.0285
Brugia malayi exodeoxyribonuclease III family protein 0.0073 0.0206 0.0391
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0171 0.0579 0.0579
Giardia lamblia Cathepsin L precursor 0.0114 0.0362 0.2443
Brugia malayi neuropeptide F receptor 0.0045 0.0096 0.0181
Echinococcus multilocularis Chromobox protein 3 0.0186 0.064 0.064
Brugia malayi beta-lactamase 0.0077 0.0222 0.042
Echinococcus multilocularis polycomb protein SCMH1 0.0096 0.0294 0.0294
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0054 0.0132 0.0251
Loa Loa (eye worm) hypothetical protein 0.0146 0.0486 0.0923
Trichomonas vaginalis ran, putative 0.0043 0.0091 0.0611
Entamoeba histolytica cysteine proteinase, putative 0.0377 0.137 1
Echinococcus multilocularis snurportin 1 0.0628 0.2333 0.2333
Giardia lamblia Cathepsin B precursor 0.0406 0.1484 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0045 0.0096 0.0596
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis histone deacetylase, putative 0.0094 0.0286 0.1926
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0077 0.0222 0.042
Trypanosoma cruzi oligopeptidase b 0.0051 0.012 0.03
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0096 0.0096
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0114 0.0362 0.2646
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0045 0.0096 0.0096
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.015 0.015
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0015 0.0028
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0789 0.2953 0.2953
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0377 0.137 0.137
Onchocerca volvulus Prolyl endopeptidase homolog 0.0128 0.0415 0.2952
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0047
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Schistosoma mansoni inhibitor of apoptosis protein 0.0054 0.0132 0.0132
Echinococcus granulosus histone acetyltransferase MYST2 0.0109 0.0345 0.0345
Brugia malayi Matrixin family protein 0.0047 0.0105 0.0198
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0114 0.0362 0.0362
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0114 0.0362 0.0687
Onchocerca volvulus 0.0045 0.0096 0.0596
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Echinococcus granulosus cathepsin l1 0.0377 0.137 0.137
Echinococcus granulosus cathepsin b 0.1059 0.3988 0.3988
Schistosoma mansoni hypothetical protein 0.0186 0.064 0.064
Echinococcus multilocularis g-protein coupled receptor 0.0045 0.0096 0.0096
Echinococcus multilocularis lamin dm0 0.0026 0.0025 0.0025
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0394 0.1435 0.1435
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0025 0.0022 0.0022
Plasmodium falciparum cysteine repeat modular protein 1 0.0053 0.0128 0.0936
Plasmodium falciparum serine repeat antigen 9 0.0114 0.0362 0.2646
Giardia lamblia Cathepsin L precursor 0.0114 0.0362 0.2443
Echinococcus multilocularis dro:myosuppressin receptor 0.0045 0.0096 0.0096
Schistosoma mansoni ap endonuclease 0.0073 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0073 0.0205 0.0388
Plasmodium falciparum thioredoxin reductase 0.0046 0.01 0.0729
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.0214
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0037 0.0067 0.0067
Trypanosoma cruzi cysteine peptidase, putative 0.0377 0.137 0.3435
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0186 0.064 0.4671
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Echinococcus multilocularis glutamate receptor 4 0.0041 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0059 0.015 0.0285
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0222 0.1144
Trypanosoma cruzi cysteine peptidase, putative 0.0377 0.137 0.3435
Onchocerca volvulus 0.0073 0.0205 0.1401
Brugia malayi Trypsin family protein 0.0025 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0096 0.0294 0.0557
Onchocerca volvulus Cathepsin F homolog 0.0377 0.137 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0187 0.0354
Schistosoma mansoni neuropeptide receptor 0.0045 0.0096 0.0096
Brugia malayi Tachykinin-like peptides receptor 99D 0.0714 0.2662 0.5049
Echinococcus multilocularis importin subunit beta 1 0.0059 0.015 0.015
Brugia malayi Trypsin family protein 0.0025 0.0022 0.0041
Entamoeba histolytica hypothetical protein 0.0186 0.064 0.4671
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Echinococcus granulosus cathepsin L cysteine protease 0.0154 0.0514 0.0514
Loa Loa (eye worm) histone deacetylase 3 0.0094 0.0286 0.0542
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0091 0.0172
Giardia lamblia Cysteine protease 0.0114 0.0362 0.2443
Brugia malayi Serotonin receptor 0.0045 0.0096 0.0181
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0074 0.0543
Loa Loa (eye worm) hypothetical protein 0.0077 0.0222 0.042
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0186 0.064 0.064
Schistosoma mansoni amine GPCR 0.0045 0.0096 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Loa Loa (eye worm) glutamate receptor 2 0.0024 0.0018 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Echinococcus granulosus cathepsin l1 0.0337 0.1218 0.1218
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0109 0.0345 0.0345
Brugia malayi Hemopexin family protein 0.0067 0.018 0.0341
Loa Loa (eye worm) matrixin family protein 0.0104 0.0324 0.0614
Brugia malayi Glutamate receptor 1 precursor 0.0066 0.0176 0.0334
Echinococcus multilocularis serotonin receptor 0.0045 0.0096 0.0096
Trypanosoma brucei histone deacetylase 4 0.0077 0.0219 0.1477
Loa Loa (eye worm) hypothetical protein 0.0047 0.0105 0.0198
Loa Loa (eye worm) hypothetical protein 0.0047 0.0105 0.0198
Loa Loa (eye worm) hypothetical protein 0.0114 0.0362 0.0687
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1059 0.3988 0.3988
Trichomonas vaginalis chromobox protein, putative 0.0186 0.064 0.4312
Echinococcus granulosus transient receptor potential gamma protein 0.0097 0.0295 0.0295
Toxoplasma gondii prolyl endopeptidase 0.0128 0.0415 0.2796
Brugia malayi RNA, U transporter 1 0.0167 0.0566 0.1074
Onchocerca volvulus 0.0045 0.0096 0.0596
Mycobacterium ulcerans hypothetical protein 0.0025 0.0022 0.0154
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Brugia malayi glutathione reductase 0.0046 0.01 0.0189
Leishmania major oligopeptidase b 0.0051 0.012 0.0806
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0477 0.0477
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Echinococcus granulosus serotonin transporter 0.0073 0.0205 0.0205
Echinococcus granulosus neuropeptide receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1027 0.6925
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0028 0.0188
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0114 0.0362 0.2443
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0078 0.0222 0.0222
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0091 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0377 0.137 0.9231
Toxoplasma gondii cathepsin B 0.0406 0.1484 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Onchocerca volvulus Cathepsin L homolog 0.0114 0.0362 0.2566
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.0324 0.6902
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Echinococcus multilocularis histone deacetylase 1 0.0094 0.0286 0.0286
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0216 0.1578
Brugia malayi Matrixin family protein 0.0113 0.036 0.0682
Trypanosoma brucei oligopeptidase b 0.0051 0.012 0.0806
Brugia malayi sulfakinin receptor protein 0.0045 0.0096 0.0181
Leishmania major cysteine peptidase A (CPA) 0.0377 0.137 0.9231
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0114 0.0362 0.2443
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0477 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Brugia malayi Cathepsin L-like precursor 0.0377 0.137 0.2597
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0015 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Trichomonas vaginalis histone deacetylase, putative 0.0094 0.0286 0.1926
Echinococcus multilocularis allatostatin A receptor 0.0179 0.0612 0.0612
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0114 0.0362 0.2214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0406 0.1484 0.3721
Loa Loa (eye worm) mbt repeat family protein 0.0096 0.0294 0.0557
Echinococcus granulosus orexin receptor type 2 0.0045 0.0096 0.0096
Schistosoma mansoni transient receptor potential channel 0.0064 0.017 0.017
Brugia malayi Sodium:solute symporter family protein 0.0037 0.0067 0.0127
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0062 0.0062
Echinococcus granulosus neuropeptide receptor 0.0045 0.0096 0.0096
Plasmodium vivax ataxin-2 like protein, putative 0.0076 0.0216 0.1083
Schistosoma mansoni amine GPCR 0.0045 0.0096 0.0096
Trypanosoma cruzi cruzipain precursor, putative 0.0377 0.137 0.3435
Schistosoma mansoni glutamate receptor AMPA 0.0024 0.0018 0.0018
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0073 0.0206 0.5
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Brugia malayi intermediate filament protein 0.0026 0.0025 0.0047
Onchocerca volvulus 0.0045 0.0096 0.0596
Brugia malayi Cathepsin L-like cysteine proteinase 0.0337 0.1218 0.231
Plasmodium falciparum heterochromatin protein 1 0.0186 0.064 0.4671
Onchocerca volvulus 0.0045 0.0096 0.0596
Giardia lamblia Cathepsin L-like protease 0.0114 0.0362 0.2443
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Schistosoma mansoni ATP-binding cassette transporter 0.0024 0.0018 0.0018
Schistosoma mansoni neuropeptide receptor 0.0045 0.0096 0.0096
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Onchocerca volvulus 0.0045 0.0096 0.0596
Schistosoma mansoni transient receptor potential channel 0.0097 0.0295 0.0295
Echinococcus granulosus polycomb protein SCMH1 0.0096 0.0294 0.0294
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0114 0.0362 0.0362
Plasmodium falciparum serine repeat antigen 5 0.0114 0.0362 0.2646
Brugia malayi Dopamine receptor protein 2 0.0045 0.0096 0.0181
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0074 0.0074
Leishmania major DNA polymerase eta, putative 0.0039 0.0074 0.0501
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0078 0.0222 0.0222
Mycobacterium leprae Probable lipase LipE 0.0077 0.0222 0.4609
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0074 0.0501
Trypanosoma cruzi histone deacetylase, putative 0.0077 0.0219 0.055
Giardia lamblia Cathepsin L precursor 0.0114 0.0362 0.2443
Echinococcus granulosus intermediate filament protein 0.0026 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0156
Schistosoma mansoni transient receptor potential channel 0.0064 0.017 0.017
Echinococcus multilocularis cysteine protease 0.0377 0.137 0.137
Trichomonas vaginalis histone deacetylase, putative 0.0094 0.0286 0.1926
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Onchocerca volvulus 0.0186 0.064 0.4612
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0074 0.0501
Echinococcus multilocularis chromobox protein 1 0.0186 0.064 0.064
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0025 0.0022 0.0022
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.1027 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0144 0.0273
Loa Loa (eye worm) hypothetical protein 0.0053 0.0128 0.0243
Giardia lamblia Cysteine protease 0.0114 0.0362 0.2443
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0051 0.012 0.0579
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0091 0.0611
Brugia malayi putative neuropeptide receptor NPR1 0.0045 0.0096 0.0181
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0477 0.0477
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0486 0.0486
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0186 0.064 0.4312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0337 0.1218 0.8211
Entamoeba histolytica cysteine protease, putative 0.0114 0.0362 0.2646
Brugia malayi Trypsin family protein 0.0025 0.0022 0.0041
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0015 0.01
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0045 0.0096 0.0181
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0091 0.0662
Brugia malayi cathepsin F-like cysteine proteinase 0.0039 0.0076 0.0144
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0628 0.2333 0.4425
Echinococcus granulosus transient receptor potential ion channel A 0.0093 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Plasmodium falciparum cysteine proteinase falcipain 3 0.0377 0.137 1
Echinococcus granulosus dna polymerase kappa 0.0039 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0096 0.0096
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0096 0.0096
Entamoeba histolytica cysteine proteinase, putative 0.0337 0.1218 0.8895
Trichomonas vaginalis esterase, putative 0.0077 0.0222 0.1493
Plasmodium falciparum importin beta, putative 0.0059 0.015 0.1097
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0114 0.0362 0.2443
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0245 0.0866 0.1642
Echinococcus granulosus G protein coupled receptor 139 0.0045 0.0096 0.0096
Onchocerca volvulus 0.0186 0.064 0.4612
Schistosoma mansoni ran 0.0043 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0034 0.0057 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0154 0.0514 0.3463
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Loa Loa (eye worm) hypothetical protein 0.0061 0.0157 0.0299
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0051 0.012 0.2334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Echinococcus granulosus dna polymerase eta 0.0039 0.0074 0.0074
Echinococcus granulosus tachykinin peptides receptor 99D 0.0045 0.0096 0.0096
Schistosoma mansoni cathepsin B (C01 family) 0.0114 0.0362 0.0362
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0114 0.0362 0.2443
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0114 0.0362 0.0362
Brugia malayi histone deacetylase 1 (HD1) 0.0094 0.0286 0.0542
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.017 0.017
Plasmodium falciparum histone deacetylase 1 0.0094 0.0286 0.2087
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0572 0.3853
Onchocerca volvulus Histone deacetylase 10 homolog 0.0049 0.0111 0.0708
Giardia lamblia Cathepsin L-like protease 0.0114 0.0362 0.2443
Echinococcus multilocularis Chromo domain 0.0186 0.064 0.064
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0222 0.0222
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0128 0.0321
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0572 0.3853
Loa Loa (eye worm) beta-lactamase 0.0077 0.0222 0.042
Echinococcus granulosus sodium:glucose cotransporter 2 0.0037 0.0067 0.0067
Brugia malayi Dopamine receptor 0.0045 0.0096 0.0181
Brugia malayi beta-lactamase family protein 0.0077 0.0222 0.042
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Echinococcus multilocularis Mastin 0.0025 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Onchocerca volvulus 0.0047 0.0105 0.0662
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0369 0.196
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0025 0.0022 0.0022
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0039 0.0076 0.0144
Mycobacterium tuberculosis Probable reductase 0.0104 0.0324 0.1713
Plasmodium vivax vivapain-3 0.0154 0.0514 0.3385
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0062 0.0118
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.017 0.017
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0037 0.0067 0.0067
Schistosoma mansoni inositol transporter 0.0037 0.0067 0.0067
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1394 0.5273 1
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0222 0.1493
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0477 0.0477
Echinococcus multilocularis glutamate receptor 2 0.0061 0.0159 0.0159
Schistosoma mansoni inositol transporter 0.0037 0.0067 0.0067
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.015 0.1013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0222 0.1125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0514 0.3463
Loa Loa (eye worm) hypothetical protein 0.0128 0.0415 0.0787
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0114 0.0362 0.0687
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0037 0.0067 0.0067
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0463 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0073 0.0206 0.1058
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Echinococcus granulosus chromobox protein 1 0.0186 0.064 0.064
Onchocerca volvulus 0.0045 0.0096 0.0596
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0018 0.0018
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0186 0.064 0.4671
Schistosoma mansoni amine GPCR 0.0045 0.0096 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0572 0.3853
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Brugia malayi Thioredoxin reductase 0.0046 0.01 0.0189
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0096 0.0096
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0074 0.0187
Schistosoma mansoni cathepsin S (C01 family) 0.0114 0.0362 0.0362
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0028 0.0188
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0073 0.0206 0.1505
Echinococcus granulosus Mastin 0.0025 0.0022 0.0022
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0091 0.0227
Echinococcus granulosus geminin 0.0532 0.1965 0.1965
Plasmodium falciparum serine repeat antigen 4 0.0114 0.0362 0.2646
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0096 0.0181
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0077 0.0222 0.042
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0045 0.0096 0.0181
Brugia malayi Heterochromatin protein 1 0.0186 0.064 0.1213
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0377 0.137 0.2597
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0114 0.0363 0.1929
Brugia malayi RE15519p 0.0045 0.0096 0.0181
Toxoplasma gondii exonuclease III APE 0.0073 0.0206 0.1389
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.01 0.0184
Brugia malayi Associated with TFs and helicases family protein 0.0186 0.064 0.1213
Echinococcus multilocularis cysteine protease 0.0377 0.137 0.137
Echinococcus granulosus solute carrier family 5 0.0037 0.0067 0.0067
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0096 0.0096
Brugia malayi hypothetical protein 0.0049 0.0113 0.0214
Onchocerca volvulus 0.0045 0.0096 0.0596
Plasmodium vivax vivapain-2 0.0377 0.137 1
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0222 0.1144
Brugia malayi Cytochrome P450 family protein 0.0048 0.0108 0.0205
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0154 0.0514 0.0514
Trypanosoma cruzi cysteine protease, putative 0.0154 0.0514 0.1289
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0222 0.1493
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Brugia malayi MH2 domain containing protein 0.025 0.0885 0.1678
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0114 0.0362 0.0362
Echinococcus multilocularis G-protein coupled receptor, putative 0.0045 0.0096 0.0096
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0074 0.0501
Echinococcus multilocularis lamin 0.0026 0.0025 0.0025
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.1027 0.6925
Schistosoma mansoni importin beta-1 0.0059 0.015 0.015
Trypanosoma cruzi cysteine proteinase, putative 0.0154 0.0514 0.1289
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0222 0.4609
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0054 0.0132 0.0251
Brugia malayi GnHR receptor homolog 0.0045 0.0096 0.0181
Plasmodium vivax vivapain-2 0.0377 0.137 1
Echinococcus multilocularis solute carrier family 5 0.0037 0.0067 0.0067
Onchocerca volvulus 0.0077 0.0222 0.1526
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0186 0.064 0.4312
Onchocerca volvulus 0.0045 0.0096 0.0596
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.01 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0074 0.0141
Loa Loa (eye worm) hypothetical protein 0.0186 0.064 0.1213
Loa Loa (eye worm) hypothetical protein 0.0077 0.0222 0.042
Trypanosoma brucei cysteine peptidase C (CPC) 0.0406 0.1484 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0257 0.0911 0.1727
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Echinococcus multilocularis neuropeptide FF receptor 2 0.0714 0.2662 0.2662
Giardia lamblia Cathepsin B precursor 0.0114 0.0362 0.2443
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0015 0.01
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0114 0.0362 0.2214
Schistosoma mansoni sodium/chloride dependent transporter 0.0073 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0039 0.0076 0.0144
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0108 0.027
Brugia malayi SWIRM domain containing protein 0.0074 0.0209 0.0396
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1059 0.3988 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0094 0.0286 0.1926
Echinococcus granulosus SAM and MBT domain containing protein 0.0096 0.0294 0.0294
Onchocerca volvulus 0.0045 0.0096 0.0596
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0039 0.0076 0.0144
Loa Loa (eye worm) hypothetical protein 0.0337 0.1218 0.231
Trypanosoma brucei histone deacetylase 1 0.0094 0.0286 0.1926
Trypanosoma brucei unspecified product 0.0027 0.0028 0.0188
Onchocerca volvulus 0.0025 0.0022 0.0051
Schistosoma mansoni neuropeptide receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0362 0.2443
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Echinococcus granulosus allatostatin A receptor 0.0179 0.0612 0.0612
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0091 0.0611
Onchocerca volvulus 0.0026 0.0025 0.0072
Trichomonas vaginalis chromobox protein, putative 0.0186 0.064 0.4312
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0036 0.0036
Trypanosoma brucei histone deacetylase 2 0.0049 0.0111 0.0747
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0362 0.2443
Brugia malayi follicle stimulating hormone receptor 0.0045 0.0096 0.0181
Brugia malayi Glutamate receptor 2 precursor 0.0066 0.0176 0.0334
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0495 0.1822 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.0324 0.1713
Echinococcus multilocularis enteropeptidase 0.0025 0.0022 0.0022
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.1027 0.7502
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0045 0.0096 0.0096
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0096 0.0096
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0045 0.0096 0.0096
Echinococcus multilocularis SAM and MBT domain containing protein 0.0096 0.0294 0.0294
Giardia lamblia Cathepsin L precursor 0.0114 0.0362 0.2443
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Brugia malayi G protein-coupled receptor F59B2.13 0.0045 0.0096 0.0181
Trypanosoma cruzi prolyl endopeptidase 0.0128 0.0415 0.104
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0025 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0109 0.0345 0.0654
Trichomonas vaginalis glucosylceramidase, putative 0.0178 0.0606 0.4088
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0047 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0128 0.0415 0.0415
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1027 0.6925
Echinococcus granulosus glutamate receptor 1 0.0041 0.0082 0.0082
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis ap endonuclease, putative 0.0073 0.0206 0.1389
Loa Loa (eye worm) hypothetical protein 0.0114 0.0362 0.0687
Leishmania major cathepsin L-like protease 0.0377 0.137 0.9231
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Mycobacterium tuberculosis Conserved protein 0.0077 0.0222 0.1144
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0477 0.0477
Loa Loa (eye worm) hypothetical protein 0.0179 0.0612 0.1161
Trypanosoma cruzi cysteine peptidase, putative 0.0377 0.137 0.3435
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0547 0.2023 0.2023
Schistosoma mansoni histone deacetylase 4 5 0.0077 0.0219 0.0219
Brugia malayi Histone deacetylase 1 0.0094 0.0286 0.0542
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0114 0.0362 0.2214
Brugia malayi Histone deacetylase family protein 0.0077 0.0219 0.0416
Entamoeba histolytica cysteine protease, putative 0.0114 0.0362 0.2646
Echinococcus granulosus histone deacetylase 3 0.0094 0.0286 0.0286
Brugia malayi neuropeptide F receptor 0.0045 0.0096 0.0181
Entamoeba histolytica cysteine proteinase, putative 0.0154 0.0514 0.3752
Brugia malayi Trypsin family protein 0.0025 0.0022 0.0041
Loa Loa (eye worm) histone deacetylase 0.0077 0.0219 0.0416
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0051 0.012 0.03
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Trichomonas vaginalis hypothetical protein 0.0186 0.064 0.4312
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0186 0.064 0.4671
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0074 0.0141
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0222 0.1493
Brugia malayi cathepsin Z-like cysteine proteinase 0.0114 0.0362 0.0687
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1059 0.3988 0.3988
Echinococcus granulosus high affinity choline transporter 1 0.0336 0.1213 0.1213
Mycobacterium tuberculosis Conserved protein 0.0077 0.0222 0.1144
Echinococcus granulosus sex peptide receptor 0.0045 0.0096 0.0096
Entamoeba histolytica cysteine proteinase, putative 0.0377 0.137 1
Echinococcus multilocularis high affinity choline transporter 1 0.0336 0.1213 0.1213
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0096 0.0096
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0186 0.064 0.064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0186 0.064 0.4312
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0045 0.0096 0.0096
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0073 0.0206 0.0517
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0186 0.064 0.064
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0114 0.0362 0.2214
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0073 0.0206 0.1389
Echinococcus multilocularis cathepsin L cysteine protease 0.0377 0.137 0.137
Loa Loa (eye worm) fibroinase 0.0377 0.137 0.2597
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0362 0.2443
Echinococcus multilocularis geminin 0.0532 0.1965 0.1965
Echinococcus multilocularis cathepsin b 0.1059 0.3988 0.3988
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) histone deacetylase 11 0.0049 0.0111 0.021
Brugia malayi Serotonin receptor 0.0045 0.0096 0.0181
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0053 0.0128 0.0403
Trypanosoma cruzi major cysteine proteinase, putative 0.0114 0.0362 0.0909
Schistosoma mansoni sodium/solute symporter 0.0037 0.0067 0.0067
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0094 0.0286 0.1926
Loa Loa (eye worm) hypothetical protein 0.0186 0.064 0.1213
Echinococcus multilocularis muscleblind protein 0.0146 0.0486 0.0486
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0096 0.0294 0.2057
Echinococcus granulosus importin subunit beta 1 0.0059 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0186 0.064 0.1213
Echinococcus granulosus g-protein coupled receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0041
Echinococcus multilocularis cathepsin L 0.0154 0.0514 0.0514
Leishmania major cathepsin L-like protease 0.0377 0.137 0.9231
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0572 0.3853
Loa Loa (eye worm) matrix metalloproteinase 0.0047 0.0105 0.0198
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0186 0.064 0.4312
Echinococcus granulosus lamin dm0 0.0026 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0073 0.0205 0.0205
Echinococcus multilocularis G protein coupled receptor 139 0.0045 0.0096 0.0096
Leishmania major cathepsin L-like protease 0.0377 0.137 0.9231
Giardia lamblia Cathepsin B precursor 0.0406 0.1484 1
Trypanosoma brucei PAB1-binding protein , putative 0.0076 0.0216 0.1457
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Leishmania major cathepsin L-like protease 0.0377 0.137 0.9231
Brugia malayi Cathepsin L-like precursor 0.0337 0.1218 0.231
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0091 0.0113
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0015 0.0028
Trypanosoma cruzi cruzipain precursor, putative 0.0039 0.0076 0.0191
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0222 0.1493
Echinococcus multilocularis GPCR, family 2 0.0078 0.0222 0.0222
Onchocerca volvulus 0.0074 0.0209 0.1432
Brugia malayi hypothetical protein 0.0111 0.0351 0.0666
Echinococcus granulosus tm gpcr rhodopsin 0.0547 0.2023 0.2023
Onchocerca volvulus 0.0045 0.0096 0.0596
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0055 0.0055
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0045 0.0096 0.0096
Onchocerca volvulus 0.0053 0.0128 0.0836
Schistosoma mansoni hypothetical protein 0.0045 0.0096 0.0096
Echinococcus granulosus Chromobox protein 3 0.0186 0.064 0.064
Brugia malayi Dopamine receptor protein 1 0.0045 0.0096 0.0181
Echinococcus granulosus chromobox protein 1 0.0186 0.064 0.064
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0074 0.0329
Schistosoma mansoni hypothetical protein 0.0045 0.0096 0.0096
Schistosoma mansoni chromobox protein 0.2626 1 1
Schistosoma mansoni hypothetical protein 0.0078 0.0222 0.0222
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0222 0.1493
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0022 0.0022
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0045 0.0096 0.0181
Loa Loa (eye worm) glutathione reductase 0.0046 0.01 0.0189
Loa Loa (eye worm) hypothetical protein 0.0076 0.0216 0.041
Brugia malayi fibroinase precursor 0.0114 0.0362 0.0687
Brugia malayi Trypsin-like protease protein 5 0.0025 0.0022 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0025 0.0022 0.0022
Onchocerca volvulus Cathepsin L homolog 0.0377 0.137 1
Echinococcus granulosus glutamate receptor 2 0.007 0.0194 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0514 0.3463
Leishmania major hypothetical protein, conserved 0.0053 0.0128 0.0864
Echinococcus multilocularis glutamate receptor subunit protein glur 0.005 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0041 0.0082 0.0156
Schistosoma mansoni cathepsin F (C01 family) 0.0377 0.137 0.137
Entamoeba histolytica cysteine protease, putative 0.0114 0.0362 0.2646
Loa Loa (eye worm) ctsf protein 0.0377 0.137 0.2597
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0186 0.064 0.4312
Loa Loa (eye worm) hypothetical protein 0.0094 0.0286 0.0542
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0406 0.1484 0.1484
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0114 0.0362 0.2214
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0041
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Onchocerca volvulus Matrilysin homolog 0.0047 0.0105 0.0662
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0477 0.0904
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Onchocerca volvulus 0.0026 0.0025 0.0072
Echinococcus granulosus glutamate receptor subunit protein glur 0.005 0.0117 0.0117
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0074 0.1327
Toxoplasma gondii cathepsin CPC1 0.0114 0.0362 0.2443
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0128 0.0415 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0114 0.0362 0.2443
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0114 0.0362 0.0362
Schistosoma mansoni histamine h1 receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) CHromoDomain protein family member 0.0186 0.064 0.1213
Brugia malayi Valyl-tRNA synthetase 0.0186 0.064 0.1213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0337 0.1218 0.8211
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Echinococcus granulosus tumor protein p63 0.0335 0.1211 0.1211
Echinococcus granulosus peptide allatostatin:somatostatin 0.0045 0.0096 0.0096
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0096 0.0294 0.0294
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.01 0.047
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0028
Onchocerca volvulus 0.0377 0.137 1
Echinococcus multilocularis somatostatin receptor 0.0045 0.0096 0.0096
Onchocerca volvulus 0.0067 0.018 0.1217
Giardia lamblia Cysteine protease 0.0114 0.0362 0.2443
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0377 0.137 0.137
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0073 0.0205 0.0388
Echinococcus multilocularis dna polymerase eta 0.0039 0.0074 0.0074
Giardia lamblia Cysteine protease 0.0114 0.0362 0.2443
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0111 0.021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Trypanosoma brucei histone deacetylase, putative 0.0077 0.0219 0.1477
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.01 0.025
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0028
Echinococcus granulosus neuropeptide s receptor 0.0045 0.0096 0.0096
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0037 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0073 0.0205 0.0388
Onchocerca volvulus Deterin homolog 0.0054 0.0132 0.0867
Echinococcus multilocularis histone deacetylase 6 0.0077 0.0219 0.0219
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0463 1
Giardia lamblia Cathepsin B precursor 0.0114 0.0362 0.2443
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0096 0.0096
Onchocerca volvulus 0.0025 0.0022 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0186 0.064 0.4312
Loa Loa (eye worm) helicase 0.0186 0.064 0.1213
Plasmodium falciparum cysteine proteinase falcipain 1 0.0154 0.0514 0.3752
Schistosoma mansoni ap endonuclease 0.0073 0.0206 0.0206
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Loa Loa (eye worm) matrixin family protein 0.0113 0.036 0.0682
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0109 0.0345 0.0345
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0045 0.0096 0.0181
Entamoeba histolytica hypothetical protein 0.0114 0.0362 0.2646
Loa Loa (eye worm) hypothetical protein 0.0337 0.1218 0.231
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Loa Loa (eye worm) TK/ROR protein kinase 0.0053 0.0128 0.0243
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Brugia malayi G-protein coupled receptor 0.0045 0.0096 0.0181
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0097 0.0295 0.056
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0062 0.0062
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0222 0.1144
Toxoplasma gondii histone deacetylase HDAC2 0.0094 0.0286 0.1926
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0078 0.0222 0.0222
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Brugia malayi SET domain containing protein 0.0186 0.064 0.1213
Echinococcus granulosus histone deacetylase 0.0077 0.0219 0.0219
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0078 0.0222 0.0422
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0015 0.0109
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0022 0.0022
Onchocerca volvulus 0.0096 0.0294 0.2057
Echinococcus granulosus neuropeptide FF receptor 2 0.0714 0.2662 0.2662
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0186 0.064 0.4312
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1027 0.6925
Brugia malayi Matrixin family protein 0.0047 0.0105 0.0198
Echinococcus granulosus muscleblind protein 0.0146 0.0486 0.0486
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0216 0.1578
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0045 0.0096 0.0181
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.015 0.3006
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0024 0.0018 0.0018
Schistosoma mansoni myosin xvIII 0.0045 0.0096 0.0096
Brugia malayi mbt repeat family protein 0.0096 0.0294 0.0557
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0362 0.2443
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0082 0.024 0.5024
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Loa Loa (eye worm) histone deacetylase 1 0.0094 0.0286 0.0542
Trypanosoma cruzi cysteine proteinase, putative 0.0154 0.0514 0.1289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0362 0.2443
Loa Loa (eye worm) hypothetical protein 0.0114 0.0362 0.0687
Toxoplasma gondii LsmAD domain-containing protein 0.0076 0.0216 0.1457
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.01 0.0189
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0362 0.2443
Brugia malayi G-protein coupled receptor 0.0045 0.0096 0.0181
Schistosoma mansoni cathepsin C 0.0114 0.0362 0.0362
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.015 0.3006
Entamoeba histolytica cysteine protease, putative 0.0114 0.0362 0.2646
Entamoeba histolytica cysteine proteinase, putative 0.0154 0.0514 0.3752
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.015 0.015
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0074 0.0501
Entamoeba histolytica histone deacetylase, putative 0.0094 0.0286 0.2087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0463 0.2482
Loa Loa (eye worm) hypothetical protein 0.0337 0.1218 0.231
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0377 0.137 0.2597
Loa Loa (eye worm) histone deacetylase 7A 0.0077 0.0219 0.0416
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Echinococcus granulosus cathepsin L cysteine proteinase 0.0377 0.137 0.137
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0406 0.1484 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0114 0.0362 0.2443
Brugia malayi mbt repeat family protein 0.0096 0.0294 0.0557
Loa Loa (eye worm) MH2 domain-containing protein 0.025 0.0885 0.1678
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0057 0.0144 0.0714
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0057 0.0144 0.0273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0362 0.2443
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0073 0.0206 0.4265
Echinococcus granulosus GPCR family 2 0.0078 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.0078 0.0222 0.0222
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0096 0.0096
Echinococcus multilocularis tumor protein p63 0.0335 0.1211 0.1211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0362 0.2443
Mycobacterium tuberculosis Conserved protein 0.0077 0.0222 0.1144
Loa Loa (eye worm) hypothetical protein 0.0114 0.0362 0.0687
Onchocerca volvulus 0.0025 0.0022 0.0051
Trypanosoma brucei histone deacetylase 3 0.0077 0.0219 0.1477
Entamoeba histolytica hypothetical protein 0.0186 0.064 0.4671
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0096 0.0096
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0186 0.064 0.4671
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0337 0.1218 0.3055
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0051 0.012 0.03
Brugia malayi putative neuropeptide receptor 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0114 0.0362 0.2443
Toxoplasma gondii ABC1 family protein 0.0077 0.0222 0.1493
Mycobacterium ulcerans lipase LipD 0.0077 0.0222 0.4609
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Echinococcus granulosus sodium:myo inositol cotransporter 0.0037 0.0067 0.0067
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0074 0.0501
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0074 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0572 0.3853
Plasmodium falciparum serine repeat antigen 1 0.0114 0.0362 0.2646
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Trypanosoma cruzi oligopeptidase b 0.0051 0.012 0.03
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Toxoplasma gondii histone deacetylase HDAC4 0.0049 0.0111 0.0747
Brugia malayi Angiotensin-converting enzyme family protein 0.1394 0.5273 1
Echinococcus multilocularis histone deacetylase 8 0.0049 0.0111 0.0111
Leishmania major importin beta-1 subunit, putative 0.0048 0.0108 0.0725
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0114 0.0362 0.0362
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0068 0.0187 0.0187
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.015 0.015
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0051 0.012 0.0806
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0109 0.0345 0.0654
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0015 0.0028
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0186 0.064 0.064
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Schistosoma mansoni glutamate receptor NMDA 0.0024 0.0018 0.0018
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0015 0.0109
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0045 0.0096 0.0181
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.01 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0039 0.0074 0.0141
Onchocerca volvulus 0.0337 0.1218 0.8882
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0062
Loa Loa (eye worm) trypsin family protein 0.0025 0.0022 0.0041
Brugia malayi Papain family cysteine protease containing protein 0.0377 0.137 0.2597
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0039 0.0076 0.0144
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0394 0.1435 0.1435
Entamoeba histolytica cysteine protease, putative 0.0377 0.137 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1027 0.6925
Plasmodium vivax hypothetical protein, conserved 0.0186 0.064 0.4357
Echinococcus multilocularis integrin beta 2 0.0518 0.1913 0.1913
Echinococcus granulosus glutamate NMDA receptor subunit 0.0024 0.0018 0.0018
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0179 0.0612 0.0612
Loa Loa (eye worm) MBCTL1 0.0109 0.0345 0.0654
Plasmodium vivax unspecified product 0.0114 0.0362 0.2214
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0127
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1059 0.3988 0.3988
Toxoplasma gondii cathepsin CPC2 0.0114 0.0362 0.2443
Plasmodium falciparum histone deacetylase, putative 0.0077 0.0219 0.16
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0096 0.0096
Brugia malayi Cathepsin L-like precursor 0.0377 0.137 0.2597
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0096 0.0096
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.0324 0.1713
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.015 0.0746
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0043
Brugia malayi hypothetical protein 0.0076 0.0216 0.041
Brugia malayi Kelch motif family protein 0.0111 0.0351 0.0666
Onchocerca volvulus 0.0377 0.137 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.015 0.1009
Leishmania major hypothetical protein, conserved 0.0077 0.0222 0.1493
Trypanosoma brucei unspecified product 0.0039 0.0074 0.0501
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0074 0.0141
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0091 0.0172
Leishmania major cathepsin L-like protease 0.0377 0.137 0.9231
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0222 0.0222
Echinococcus granulosus cysteine protease 0.0154 0.0514 0.0514
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0025 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0572 0.3853
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0186 0.064 0.4312
Brugia malayi Cathepsin L-like precursor 0.0377 0.137 0.2597
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0054 0.0132 0.0132
Onchocerca volvulus 0.0037 0.0067 0.0383
Toxoplasma gondii histone deacetylase HDAC3 0.0094 0.0286 0.1926
Echinococcus granulosus histone deacetylase 6 0.0077 0.0219 0.0219
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0045 0.0096 0.0096
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.1027 0.7502
Loa Loa (eye worm) hypothetical protein 0.0077 0.0222 0.042
Onchocerca volvulus Glucosylceramidase homolog 0.0169 0.0572 0.411
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0074 0.0074
Plasmodium vivax hypothetical protein, conserved 0.0186 0.064 0.4357
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) transcription factor SMAD2 0.025 0.0885 0.1678
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0114 0.0362 0.0362
Echinococcus granulosus somatostatin receptor 0.0045 0.0096 0.0096
Schistosoma mansoni neuropeptide f receptor 76f 0.0045 0.0096 0.0096
Entamoeba histolytica cysteine protease, putative 0.0114 0.0362 0.2646
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Giardia lamblia Hypothetical protein 0.0114 0.0362 0.2443
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0045 0.0096 0.0181
Echinococcus granulosus histone deacetylase 1 0.0094 0.0286 0.0286
Trichomonas vaginalis histone deacetylase, putative 0.0094 0.0286 0.1926
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.015 0.3006
Schistosoma mansoni opsin-like receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1027 0.6925
Toxoplasma gondii histone deacetylase HDAC1 0.0077 0.0219 0.1477
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0096 0.0096
Echinococcus granulosus fmrfamide receptor 0.0045 0.0096 0.0096
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0222 0.1144
Plasmodium vivax heterochromatin protein 1, putative 0.0186 0.064 0.4357
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0186 0.064 0.4312
Onchocerca volvulus 0.0025 0.0022 0.0051
Loa Loa (eye worm) integrin beta-2 0.0708 0.2641 0.5008
Echinococcus multilocularis histone acetyltransferase MYST2 0.0109 0.0345 0.0345
Plasmodium vivax histone deacetylase 1, putative 0.0094 0.0286 0.1622
Schistosoma mansoni hypothetical protein 0.0025 0.0022 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Schistosoma mansoni sex comb on midleg homolog 0.0096 0.0294 0.0294
Onchocerca volvulus 0.0377 0.137 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0036 0.0062 0.0118
Echinococcus multilocularis chromobox protein 1 0.0186 0.064 0.064
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0096 0.0096
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0114 0.0362 0.2443
Echinococcus granulosus g protein coupled receptor 0.0045 0.0096 0.0096
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Schistosoma mansoni opsin-like receptor 0.0045 0.0096 0.0096
Onchocerca volvulus Neuropeptide F receptor homolog 0.0045 0.0096 0.0596
Leishmania major DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Trypanosoma cruzi major cysteine proteinase, putative 0.0114 0.0362 0.0909
Brugia malayi CHD4 protein 0.0186 0.064 0.1213
Entamoeba histolytica Ran family GTPase 0.0043 0.0091 0.0662
Loa Loa (eye worm) solute carrier family 6 member 4 0.0073 0.0205 0.0388
Brugia malayi Cathepsin L-like precursor 0.0039 0.0076 0.0144
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0911 0.6138
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0186 0.064 0.4612
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trypanosoma cruzi cysteine peptidase, putative 0.0039 0.0076 0.0191
Brugia malayi Melatonin receptor type 1A 0.0045 0.0096 0.0181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0377 0.137 0.9231
Trichomonas vaginalis Heterochromatin protein, putative 0.0186 0.064 0.4312
Brugia malayi histone deacetylase 11 0.0049 0.0111 0.021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0041
Echinococcus granulosus Chromo domain 0.0186 0.064 0.064
Onchocerca volvulus 0.0045 0.0096 0.0596
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.015 0.015
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0477 0.0477
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Giardia lamblia Cathepsin L precursor 0.0114 0.0362 0.2443
Schistosoma mansoni hypothetical protein 0.0168 0.0568 0.0568
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0911 0.6138
Leishmania major trypanothione reductase 0.0046 0.01 0.0673
Schistosoma mansoni hypothetical protein 0.0532 0.1965 0.1965
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0096 0.0096
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0222 0.4609
Onchocerca volvulus Matrilysin homolog 0.0104 0.0324 0.228
Echinococcus granulosus neuropeptide receptor A26 0.0045 0.0096 0.0096
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0045 0.0096 0.0181
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Schistosoma mansoni hypothetical protein 0.0034 0.0055 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0078 0.0222 0.0222
Echinococcus granulosus cathepsin l cysteine peptidase 0.0377 0.137 0.137
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Brugia malayi M-phase phosphoprotein, mpp8 0.0186 0.064 0.1213
Echinococcus granulosus g protein coupled receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0186 0.064 0.1213
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0186 0.064 0.064
Echinococcus multilocularis neuropeptide receptor A26 0.0045 0.0096 0.0096
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0096 0.0181
Echinococcus granulosus hypothetical protein 0.0045 0.0096 0.0096
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0096 0.0181
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0073 0.0206 0.0206
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0096 0.0096
Schistosoma mansoni alpha-1 adrenergic receptor 0.0045 0.0096 0.0096
Schistosoma mansoni lamin 0.0026 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0222 0.1493
Brugia malayi larval opioid receptor 0.0045 0.0096 0.0181
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0114 0.0362 0.2214
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0154 0.0514 0.1289
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0041
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0186 0.064 0.4312
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Brugia malayi Cathepsin L-like precursor 0.0377 0.137 0.2597
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0377 0.137 0.9231
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0025 0.0022 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Trypanosoma brucei prolyl oligopeptidase, putative 0.0051 0.012 0.0806
Brugia malayi ORL1-like opioid receptor 0.0045 0.0096 0.0181
Trypanosoma cruzi cysteine peptidase, putative 0.0377 0.137 0.3435
Brugia malayi Latrophilin receptor protein 2 0.0078 0.0222 0.0422
Brugia malayi Cathepsin L-like precursor 0.0377 0.137 0.2597
Echinococcus multilocularis transmembrane protease serine 3 0.0025 0.0022 0.0022
Plasmodium falciparum glutathione reductase 0.0046 0.01 0.0729
Plasmodium falciparum serine repeat antigen 2 0.0114 0.0362 0.2646
Brugia malayi Matrixin family protein 0.0047 0.0105 0.0198
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0045 0.0096 0.0181
Schistosoma mansoni histone deacetylase hda2 0.0049 0.0111 0.0111
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0051 0.012 0.0806
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0911 0.6138
Echinococcus multilocularis histone deacetylase 7 0.0077 0.0219 0.0219
Brugia malayi cathepsin L-like precursor 0.0337 0.1218 0.231
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0114 0.0362 0.2214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Echinococcus granulosus glycoprotein Antigen 5 0.0025 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0114 0.0362 0.2443
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0114 0.0362 0.2646
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Schistosoma mansoni hypothetical protein 0.0025 0.0022 0.0022
Echinococcus multilocularis cathepsin L 0.0114 0.0362 0.0362
Trichomonas vaginalis glucosylceramidase, putative 0.0169 0.0572 0.3853
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0114 0.0362 0.2646
Brugia malayi Papain family cysteine protease containing protein 0.0114 0.0362 0.0687
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0045 0.0096 0.0096
Onchocerca volvulus 0.0077 0.0222 0.1526
Brugia malayi Matrixin family protein 0.0047 0.0105 0.0198
Brugia malayi prolyl oligopeptidase family protein 0.0128 0.0415 0.0787
Brugia malayi cathepsin Z-like cysteine proteinase 0.0114 0.0362 0.0687
Trichomonas vaginalis ap endonuclease, putative 0.0073 0.0206 0.1389
Toxoplasma gondii cathepsin CPL 0.0377 0.137 0.9231
Loa Loa (eye worm) hypothetical protein 0.0047 0.0105 0.0198
Schistosoma mansoni glutamate receptor AMPA 0.0024 0.0018 0.0018
Leishmania major histone deacetylase, putative 0.0094 0.0286 0.1926
Echinococcus granulosus lysine specific histone demethylase 1A 0.0068 0.0187 0.0187
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0096 0.0096
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0186 0.064 0.4312
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0114 0.0362 0.2214
Brugia malayi Protein kinase domain containing protein 0.0053 0.0128 0.0243
Schistosoma mansoni amine GPCR 0.0045 0.0096 0.0096
Mycobacterium ulcerans hypothetical protein 0.0077 0.0222 0.4609
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0073 0.0206 0.0391
Schistosoma mansoni hypothetical protein 0.0078 0.0222 0.0222
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0369 0.196
Echinococcus granulosus lamin 0.0026 0.0025 0.0025
Echinococcus multilocularis sex peptide receptor 0.0045 0.0096 0.0096
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0074 0.0187
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0096 0.0096
Echinococcus granulosus 7tm_1 domain containing protein 0.0045 0.0096 0.0096
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0045 0.0096 0.0096
Echinococcus granulosus sodium:glucose cotransporter 0.0037 0.0067 0.0067
Echinococcus granulosus glutamate receptor 2 0.0061 0.0159 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Onchocerca volvulus 0.0054 0.0132 0.0867
Brugia malayi hypothetical protein 0.0025 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Echinococcus multilocularis orexin receptor type 2 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.1059 0.3988 0.7562
Brugia malayi Cathepsin L-like precursor 0.0377 0.137 0.2597
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.015 0.1013
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0096 0.0096
Echinococcus multilocularis serotonin receptor 0.0045 0.0096 0.0096
Plasmodium falciparum serine repeat antigen 7 0.0114 0.0362 0.2646
Trichomonas vaginalis glucosylceramidase, putative 0.0257 0.0911 0.6138
Loa Loa (eye worm) TYRA-2 protein 0.0045 0.0096 0.0181
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0018 0.0018
Brugia malayi hypothetical protein 0.0186 0.064 0.1213
Brugia malayi chromobox protein homolog 3 0.0186 0.064 0.1213
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0114 0.0362 0.2214
Plasmodium vivax serine-repeat antigen (SERA) 0.0114 0.0362 0.2214
Leishmania major cathepsin L-like protease 0.0377 0.137 0.9231
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0377 0.137 0.9231
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0369 0.7896
Echinococcus granulosus cathepsin L 0.0154 0.0514 0.0514
Giardia lamblia Cathepsin B precursor 0.0406 0.1484 1
Onchocerca volvulus Cathepsin L homolog 0.0377 0.137 1
Echinococcus granulosus histone deacetylase 8 0.0049 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0114 0.0362 0.0687
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.0324 0.1713
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0186 0.064 0.1213
Schistosoma mansoni biogenic amine receptor 0.0045 0.0096 0.0096
Schistosoma mansoni intermediate filament proteins 0.0026 0.0025 0.0025
Echinococcus granulosus g protein coupled receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis chromobox protein, putative 0.0186 0.064 0.4312
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.0324 0.1713
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0114 0.0362 0.0687
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0377 0.137 0.9231
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.0324 0.1713
Entamoeba histolytica cysteine protease, putative 0.0154 0.0514 0.3752
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0096 0.0096
Trichomonas vaginalis chromobox protein, putative 0.0186 0.064 0.4312
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.00000000003432 0.00000000023132
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0096 0.0096
Giardia lamblia Cathepsin B precursor 0.0114 0.0362 0.2443
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0074 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.0362 0.2443
Brugia malayi Histone deacetylase family protein 0.0077 0.0219 0.0416
Schistosoma mansoni hypothetical protein 0.0067 0.018 0.018
Leishmania major histone deacetylase, putative 0.0077 0.0219 0.1477
Plasmodium vivax histone deacetylase, putative 0.0077 0.0219 0.1106
Schistosoma mansoni histone deacetylase 1 2 3 0.0049 0.0111 0.0111
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0377 0.137 1
Echinococcus multilocularis inhibitor of apoptosis protein 0.0054 0.0132 0.0132
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0036 0.0036
Brugia malayi cathepsin L precursor 0.0114 0.0362 0.0687
Toxoplasma gondii histone deacetylase HDAC5 0.0049 0.0111 0.0747
Plasmodium vivax histone deacetylase 2, putative 0.0077 0.0219 0.1106
Giardia lamblia Hypothetical protein 0.0114 0.0362 0.2443
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0045 0.0096 0.0096
Schistosoma mansoni cathepsin F (C01 family) 0.0377 0.137 0.137
Schistosoma mansoni hypothetical protein 0.0532 0.1965 0.1965
Toxoplasma gondii kringle domain-containing protein 0.0053 0.0128 0.0864
Leishmania major cathepsin L-like protease 0.0377 0.137 0.9231
Echinococcus multilocularis glutamate receptor 2 0.007 0.0194 0.0194
Toxoplasma gondii thioredoxin reductase 0.0046 0.01 0.0673
Brugia malayi hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0041
Brugia malayi Papain family cysteine protease containing protein 0.0114 0.0362 0.0687
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0186 0.064 0.4312
Loa Loa (eye worm) hypothetical protein 0.0045 0.0096 0.0181
Giardia lamblia Encystation-specific protease 0.0114 0.0362 0.2443
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0073 0.0206 0.1505
Schistosoma mansoni hypothetical protein 0.0599 0.2224 0.2224
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0074 0.0501
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0054 0.0132 0.0132
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0108 0.0725
Schistosoma mansoni biogenic amine receptor 0.0045 0.0096 0.0096
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0113 0.0113
Trypanosoma brucei unspecified product 0.0027 0.0028 0.0188
Schistosoma mansoni high-affinity choline transporter 0.0336 0.1213 0.1213
Echinococcus granulosus serotonin receptor 0.0045 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0114 0.0362 0.0687
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0015 0.0109
Schistosoma mansoni cercarial elastase (S01 family) 0.0025 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0022 0.0041
Giardia lamblia Cathepsin B precursor 0.0114 0.0362 0.2443
Brugia malayi GH02984p 0.0336 0.1213 0.23
Loa Loa (eye worm) hypothetical protein 0.0054 0.0132 0.0251
Schistosoma mansoni transient receptor potential channel 4 0.0097 0.0295 0.0295
Schistosoma mansoni histone deacetylase 0.0094 0.0286 0.0286
Schistosoma mansoni integrin beta subunit 0.0407 0.1487 0.1487
Loa Loa (eye worm) heterochromatin protein 1 0.0186 0.064 0.1213
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0114 0.0362 0.2646
Echinococcus granulosus cathepsin L 0.0114 0.0362 0.0362
Schistosoma mansoni hypothetical protein 0.0054 0.0132 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0186 0.064 0.4312
Echinococcus granulosus transmembrane protease serine 3 0.0025 0.0022 0.0022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0096 0.0096
Echinococcus granulosus snurportin 1 0.0628 0.2333 0.2333
Entamoeba histolytica cysteine protease, putative 0.0114 0.0362 0.2646
Mycobacterium ulcerans hydrolase 0.0057 0.0144 0.2875
Echinococcus multilocularis cathepsin b 0.1059 0.3988 0.3988
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0186 0.064 0.064
Loa Loa (eye worm) cysteine protease 0.0377 0.137 0.2597
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0091 0.0227
Onchocerca volvulus 0.0045 0.0096 0.0596
Plasmodium vivax vivapain-1 0.0154 0.0514 0.3385
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0096 0.0096
Schistosoma mansoni lamin 0.0026 0.0025 0.0025
Trichomonas vaginalis chromobox protein, putative 0.0186 0.064 0.4312
Onchocerca volvulus 0.0377 0.137 1
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0108 0.0725
Brugia malayi Papain family cysteine protease containing protein 0.0154 0.0514 0.0974

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 4.56 nM In vitro radioligand [3H]-paroxetine from rat cortical Serotonin transporter ChEMBL. 11128642
Ki (binding) = 4.56 nM In vitro radioligand [3H]-paroxetine from rat cortical Serotonin transporter ChEMBL. 11128642
Ki (binding) = 22.19 nM Inhibition of [3H]-citalopram binding to Serotonin transporter of rat cerebral cortex ChEMBL. 10915050
Ki (binding) = 22.19 nM Inhibition of [3H]-citalopram binding to Serotonin transporter of rat cerebral cortex ChEMBL. 10915050
Ratio (binding) = 28 Equipotent molar ratio of compound to that of standard (compound 1) was evaluated ChEMBL. 11128642

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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