Detailed information for compound 672787

Basic information

Technical information
  • TDR Targets ID: 672787
  • Name: Oprea1_585916
  • MW: 367.782 | Formula: C20H14ClNO4
  • H donors: 2 H acceptors: 3 LogP: 4.44 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)Oc1ccc(cc1)NC(=O)c1ccccc1C(=O)O
  • InChi: 1S/C20H14ClNO4/c21-13-5-9-15(10-6-13)26-16-11-7-14(8-12-16)22-19(23)17-3-1-2-4-18(17)20(24)25/h1-12H,(H,22,23)(H,24,25)
  • InChiKey: BPOAUEXGDJJVAJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • STK252444

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0538 0.0542
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Brugia malayi Glycosyl hydrolases family 31 protein 0.0181 0.1747 0.1993
Schistosoma mansoni sugar transporter 0.0031 0.0177 0.02
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0002
Brugia malayi jmjC domain containing protein 0.0057 0.0448 0.0511
Leishmania major cathepsin L-like protease 0.0019 0.0057 0.014
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0057 0.0047
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0067
Trypanosoma brucei ISWI complex protein 0.0033 0.0194 0.0549
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0178 0.1713 1
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0057 0.0769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0178 0.1713 1
Schistosoma mansoni alpha-glucosidase 0.0156 0.1484 0.1789
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0057 0.014
Toxoplasma gondii hypothetical protein 0.0054 0.042 0.0642
Echinococcus multilocularis muscleblind protein 1 0.0163 0.1556 0.1592
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.1515 0.4487
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0061 0.0494 0.0502
Brugia malayi PHD-finger family protein 0.0053 0.0408 0.0465
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0568 0.0574
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0177 0.0167
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0274 0.0264
Plasmodium vivax thioredoxin reductase, putative 0.0055 0.0428 0.0433
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0053 0.0049
Leishmania major hypothetical protein, conserved 0.0015 0.0012 0.0006
Leishmania major GTP-binding protein, putative 0.0021 0.0069 0.0174
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0375 0.0416
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0177 0.0167
Echinococcus granulosus methyl CpG binding domain protein 2 0.0036 0.0233 0.0269
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0538 0.0602
Onchocerca volvulus 0.0031 0.0177 0.0167
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0019 0.0053 0.0028
Plasmodium falciparum mitogen-activated protein kinase 2 0.0356 0.3579 0.3712
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0448 0.053
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0568 0.0574
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0057 0.0047
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0021 0.0073 0.1036
Brugia malayi Sugar transporter family protein 0.0031 0.0177 0.0202
Trypanosoma brucei sugar transporter, putative 0.0031 0.0177 0.0497
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Entamoeba histolytica Ran family GTPase 0.0021 0.0069 0.0954
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0021 0.0073 0.0189
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0177 0.0202
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0117 0.1072 0.619
Echinococcus multilocularis apoptotic protease activating factor 1 0.0212 0.2066 0.2118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0127 0.1182 0.1422
Toxoplasma gondii lysine-tRNA ligase 0.0049 0.0367 0.0559
Plasmodium falciparum glutathione reductase 0.0055 0.0428 0.0433
Plasmodium vivax metacaspase 1, putative 0.0146 0.1384 0.1428
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.012 0.1109 0.3276
Loa Loa (eye worm) hypothetical protein 0.0019 0.0049 0.0044
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0053 0.0127
Schistosoma mansoni protein kinase 0.0068 0.0568 0.0676
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0178 0.1713 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Schistosoma mansoni hypothetical protein 0.0298 0.2969 0.3595
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0124 0.1148 0.6646
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0021 0.0073 0.0189
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0274 0.0312
Echinococcus multilocularis Protein lozenge 0.0062 0.05 0.0503
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0367 0.1913
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0124 0.1148 0.6605
Loa Loa (eye worm) hypothetical protein 0.0163 0.1556 0.1765
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0076 0.0648 0.0772
Trichomonas vaginalis CMGC family protein kinase 0.012 0.1109 0.11
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0274 0.0264
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0048 0.0113
Loa Loa (eye worm) hypothetical protein 0.0076 0.0648 0.0728
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0621 0.0628
Onchocerca volvulus 0.0031 0.0177 0.0167
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0049 0.0005
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0066 0.0543 0.8728
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0658 0.193
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0159 0.1512 0.1823
Loa Loa (eye worm) hypothetical protein 0.0087 0.076 0.0856
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0274 0.0264
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.0448 0.053
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0049 0.0005
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0347 0.1005
Leishmania major cathepsin L-like protease 0.0074 0.0629 0.1845
Echinococcus multilocularis mitogen activated protein kinase 0.012 0.1109 0.1131
Trypanosoma brucei glucose transporter 2A 0.0068 0.0567 0.1659
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0177 0.0773
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0031 0.0177 0.0778
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Onchocerca volvulus 0.0031 0.0177 0.0167
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0029 0.0156 0.0177
Schistosoma mansoni bromodomain containing protein 0.0135 0.1262 0.1519
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0336 0.3364 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0068 0.0569 0.0579
Brugia malayi Probable ClpP-like protease 0.0178 0.1713 0.1953
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0356 0.3579 0.3712
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0177 0.0167
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0057 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Echinococcus granulosus zinc finger protein 0.0042 0.0289 0.0337
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.1384 0.1375
Schistosoma mansoni alpha-glucosidase 0.0156 0.1484 0.1789
Brugia malayi Pre-SET motif family protein 0.0122 0.1132 0.1291
Trypanosoma cruzi hexose transporter 0.0068 0.0567 0.1659
Schistosoma mansoni hypothetical protein 0.0065 0.0538 0.0639
Echinococcus granulosus solute carrier family 22 0.0031 0.0177 0.02
Loa Loa (eye worm) hypothetical protein 0.0065 0.0538 0.0602
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Schistosoma mansoni peptidase Clp (S14 family) 0.0178 0.1713 0.2067
Schistosoma mansoni ran 0.0021 0.0069 0.0068
Brugia malayi Muscleblind-like protein 0.0163 0.1556 0.1774
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.5469 0.5465
Leishmania major importin beta-1 subunit, putative 0.0023 0.009 0.0239
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0048 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.5469 0.5465
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.0658 0.193
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0048 0.0113
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0178 0.1713 1
Leishmania major DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Echinococcus granulosus solute carrier family 22 0.0031 0.0177 0.02
Trypanosoma cruzi cruzipain precursor, putative 0.0074 0.0629 0.1845
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0053 0.0127
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0049 0.0005
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0055 0.0428 0.2297
Echinococcus granulosus caspase 8 0.0146 0.1384 0.1668
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0049 0.0045
Echinococcus granulosus lysosomal alpha glucosidase 0.0181 0.1747 0.2109
Plasmodium vivax hexose transporter 0.022 0.2152 0.2227
Brugia malayi hypothetical protein 0.0031 0.0177 0.0202
Onchocerca volvulus 0.0019 0.0057 0.0047
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.016 0.0233
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0048 0.0113
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0178 0.1713 0.268
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Schistosoma mansoni hypothetical protein 0.0065 0.0538 0.0639
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Brugia malayi glutathione reductase 0.0055 0.0428 0.0488
Brugia malayi Calcitonin receptor-like protein seb-1 0.0207 0.2015 0.2298
Loa Loa (eye worm) hypothetical protein 0.0066 0.0543 0.0609
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.049 0.0581
Onchocerca volvulus 0.0031 0.0177 0.0167
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0274 0.027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0139 0.1311 0.7174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0012 0.0006
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0567 0.1659
Echinococcus granulosus mitogen activated protein kinase 0.012 0.1109 0.1333
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0629 0.1845
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0053 0.0127
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0543 0.0646
Trichomonas vaginalis glucosylceramidase, putative 0.0371 0.3737 0.373
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0048 0.0355 0.0354
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0073 0.0189
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.012 0.1109 0.1728
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0274 0.0318
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0139 0.1311 0.763
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0375 0.0374
Schistosoma mansoni sugar transporter 0.0031 0.0177 0.02
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0076 0.0653 0.0661
Plasmodium falciparum calcium-dependent protein kinase 5 0.0068 0.0569 0.0579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0012 0.0006
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0177 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Echinococcus granulosus neuropeptide s receptor 0.0543 0.5531 0.6709
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0061 0.0494 0.2679
Onchocerca volvulus 0.0105 0.0949 0.094
Leishmania major lysyl-tRNA synthetase, putative 0.0049 0.0367 0.1063
Loa Loa (eye worm) cysteine protease 0.0019 0.0057 0.0054
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0568 0.0574
Loa Loa (eye worm) hypothetical protein 0.0054 0.0414 0.0461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0124 0.1148 0.1171
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0057 0.0047
Schistosoma mansoni ap endonuclease 0.0019 0.0048 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.5469 0.5465
Schistosoma mansoni microtubule-associated protein tau 0.0802 0.8239 1
Schistosoma mansoni caspase-7 (C14 family) 0.0358 0.3596 0.4357
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0068 0.0569 0.0877
Echinococcus granulosus snurportin 1 0.0298 0.2969 0.3595
Loa Loa (eye worm) PHD-finger family protein 0.0044 0.0313 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0568 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0567 0.0557
Trichomonas vaginalis CMGC family protein kinase 0.012 0.1109 0.11
Schistosoma mansoni glucose transporter 0.0031 0.0177 0.02
Mycobacterium ulcerans hypothetical protein 0.0177 0.1703 0.9939
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.0174
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0621 0.1821
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.0448 0.0449
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.1384 0.1375
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0021 0.0073 0.0189
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0068 0.0568 0.0637
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Loa Loa (eye worm) sugar transporter 0.022 0.2152 0.2446
Echinococcus multilocularis neuropeptide receptor A26 0.0543 0.5531 0.5693
Echinococcus multilocularis calcium dependent protein kinase 0.0063 0.0514 0.0518
Loa Loa (eye worm) hypothetical protein 0.0082 0.0708 0.0796
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0061 0.0494 0.0502
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0057 0.0055
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0538 0.0639
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Schistosoma mansoni caspase-7 (C14 family) 0.0298 0.2974 0.36
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0053 0.0127
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Brugia malayi jmjC domain containing protein 0.0015 0.0012 0.0014
Echinococcus multilocularis lysosomal alpha glucosidase 0.0181 0.1747 0.179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Loa Loa (eye worm) runx1 0.0062 0.05 0.0559
Echinococcus multilocularis neuropeptide s receptor 0.0543 0.5531 0.5693
Trypanosoma brucei metacaspase MCA3 0.0146 0.1384 0.4097
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.0174
Brugia malayi jmjC domain containing protein 0.0015 0.0012 0.0014
Brugia malayi MAP kinase sur-1 0.012 0.1109 0.1265
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0049 0.0005
Echinococcus multilocularis General substrate transporter 0.0189 0.1829 0.1874
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.016 0.0154
Onchocerca volvulus 0.0212 0.2066 0.2058
Toxoplasma gondii sugar transporter ST2 0.0031 0.0177 0.026
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0621 0.074
Trypanosoma cruzi metacaspase, putative 0.0146 0.1384 0.4097
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Leishmania major cathepsin L-like protease 0.0019 0.0057 0.014
Trypanosoma cruzi metacaspase 5, putative 0.0146 0.1384 0.4097
Mycobacterium tuberculosis Probable oxidoreductase 0.0139 0.1311 0.763
Schistosoma mansoni sugar transporter 0.0031 0.0177 0.02
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.016 0.0447
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.016 0.0447
Echinococcus multilocularis mitogen activated protein kinase 3 0.012 0.1109 0.1131
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0021 0.0073 0.0189
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0567 0.0557
Toxoplasma gondii thioredoxin reductase 0.0055 0.0428 0.0656
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0019 0.0053 0.0028
Onchocerca volvulus 0.0019 0.0057 0.0047
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0177 0.026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0375 0.0428
Loa Loa (eye worm) thioredoxin reductase 0.0055 0.0428 0.0477
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0019 0.0053 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0352 0.3538 0.3532
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0177 0.02
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0146 0.1384 0.2162
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0049 0.0044
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0053 0.0127
Loa Loa (eye worm) hypothetical protein 0.0146 0.1384 0.1569
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0125 0.1164 0.6746
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0053 0.0043
Echinococcus granulosus solute carrier family 22 0.0031 0.0177 0.02
Echinococcus granulosus GPCR family 2 0.0065 0.0538 0.0639
Mycobacterium tuberculosis Probable dehydrogenase 0.0125 0.1164 0.6746
Entamoeba histolytica protein kinase, putative 0.0068 0.0568 0.9141
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0117 0.1072 0.619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0074 0.019
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.049 0.0581
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0049 0.0367 0.0357
Trypanosoma cruzi metacaspase 5, putative 0.0146 0.1384 0.4097
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0053 0.0127
Brugia malayi hypothetical protein 0.0029 0.016 0.0183
Onchocerca volvulus 0.0031 0.0177 0.0167
Brugia malayi Cathepsin L-like precursor 0.0019 0.0057 0.0065
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2152 0.2207
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Schistosoma mansoni hypothetical protein 0.0044 0.0313 0.0366
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.012 0.1109 0.3276
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0621 1
Echinococcus granulosus neuropeptide receptor A26 0.0543 0.5531 0.6709
Trypanosoma brucei trypanothione reductase 0.0055 0.0428 0.1247
Echinococcus granulosus peptidase Clp S14 family 0.0117 0.1072 0.1289
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.049 0.0581
Trypanosoma brucei glucosidase, putative 0.004 0.0274 0.0786
Trichomonas vaginalis set domain proteins, putative 0.097 1 1
Plasmodium falciparum metacaspase-like protein 0.0146 0.1384 0.1428
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Onchocerca volvulus Putative transporter 0.0031 0.0177 0.0167
Schistosoma mansoni hypothetical protein 0.0518 0.527 0.6391
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.1132 0.1155
Plasmodium falciparum calcium-dependent protein kinase 1 0.0068 0.0569 0.0579
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0053 0.0042
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0049 0.0367 0.0543
Plasmodium falciparum proline--tRNA ligase 0.0077 0.0658 0.0672
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0114 0.1044 0.1254
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0068 0.0569 0.0877
Leishmania major myo-inositol/proton symporter (MIT) 0.0031 0.0177 0.0497
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0114 0.1044 0.1254
Onchocerca volvulus 0.0031 0.0177 0.0167
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0049 0.0116
Leishmania major cathepsin L-like protease 0.0019 0.0057 0.014
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0053 0.0127
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0367 0.0431
Echinococcus granulosus histone lysine methyltransferase setb 0.0159 0.1512 0.1823
Entamoeba histolytica cysteine protease, putative 0.0019 0.0057 0.0769
Brugia malayi Cathepsin L-like precursor 0.0019 0.0057 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.012 0.1109 0.1333
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0048 0.0043
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.012 0.1109 0.3276
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0568 0.0559
Trypanosoma brucei metacaspase 5, putative 0.0146 0.1384 0.4097
Trypanosoma brucei glucose transporter, putative 0.0068 0.0567 0.1659
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0375 0.0441
Plasmodium vivax vivapain-2 0.0019 0.0057 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0057 0.014
Schistosoma mansoni DNA polymerase eta 0.0019 0.0049 0.0045
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0043 0.0304 0.0294
Trypanosoma brucei Metacaspase-4 0.0146 0.1384 0.4097
Plasmodium falciparum importin beta, putative 0.0028 0.0146 0.0139
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0367 0.1913
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0146 0.0404
Toxoplasma gondii target of rapamycin (TOR), putative 0.0021 0.0073 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Plasmodium falciparum hexose transporter 0.022 0.2152 0.2227
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Leishmania major glucose transporter, lmgt1 0.0068 0.0567 0.1659
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Brugia malayi latrophilin 2 splice variant baaae 0.0141 0.1331 0.1518
Trypanosoma brucei glucose transporter, putative 0.0068 0.0567 0.1659
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.5469 0.5465
Onchocerca volvulus 0.0031 0.0177 0.0167
Schistosoma mansoni hypothetical protein 0.0033 0.0194 0.0221
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1062 0.1201
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0177 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2152 0.2601
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0538 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.0233 0.0269
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0146 0.1384 0.1668
Echinococcus multilocularis caspase 3 0.0152 0.1444 0.1476
Echinococcus multilocularis solute carrier family 22 0.0031 0.0177 0.017
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0658 0.193
Trypanosoma cruzi glucose transporter, putative 0.0031 0.0177 0.0497
Plasmodium vivax vivapain-2 0.0019 0.0057 0.0047
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0049 0.0116
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.012 0.1109 0.3276
Trichomonas vaginalis glucosylceramidase, putative 0.0352 0.3538 0.3532
Plasmodium vivax CDK-related protein kinase 6, putative 0.0934 0.962 1
Brugia malayi Importin beta-1 subunit 0.0028 0.0146 0.0166
Leishmania major glucose transporter, lmgt3 0.0068 0.0567 0.1659
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0021 0.0073 0.0189
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0567 0.1659
Plasmodium vivax sugar transporter, putative 0.0031 0.0177 0.0171
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trichomonas vaginalis importin beta-1, putative 0.0023 0.009 0.008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0073 0.0084
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2152 0.2207
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0375 0.0441
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0274 0.0786
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0036 0.0233 0.0228
Brugia malayi Thioredoxin reductase 0.0055 0.0428 0.0488
Echinococcus multilocularis muscleblind protein 0.0163 0.1556 0.1592
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0053 0.0127
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0002
Echinococcus granulosus caspase 2 0.0358 0.3596 0.4357
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Echinococcus multilocularis caspase 0.0298 0.2974 0.3055
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0073 0.0072
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0053 0.0049
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0375 0.0441
Giardia lamblia Prolyl-tRNA synthetase 0.0066 0.0543 0.4667
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.1384 0.1375
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0076 0.0648 0.0772
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0057 0.0047
Brugia malayi follicle stimulating hormone receptor 0.0489 0.497 0.5668
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0049 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Leishmania major glucose transporter, lmgt2 0.0068 0.0567 0.1659
Brugia malayi hypothetical protein 0.0031 0.0177 0.0202
Schistosoma mansoni protein kinase 0.0068 0.0568 0.0676
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0061 0.0494 0.1439
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.1132 0.1362
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0159 0.1515 0.4487
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0057 0.0046
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0567 0.1659
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.0463 0.135
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0177 0.0773
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0066 0.0543 0.0534
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0066 0.0543 0.062
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0543 0.0646
Plasmodium vivax SET domain protein, putative 0.0122 0.1132 0.1166
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0127 0.1182 0.1207
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0073 0.0084
Onchocerca volvulus 0.0019 0.0057 0.0047
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0621 0.1821
Brugia malayi Pre-SET motif family protein 0.0852 0.8768 1
Echinococcus granulosus General substrate transporter 0.0189 0.1829 0.2208
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0053 0.0042
Plasmodium falciparum protein kinase 7 0.0622 0.6359 0.6606
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0048 0.0038
Trypanosoma brucei metacaspase MCA2 0.0146 0.1384 0.4097
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0021 0.0073 0.1036
Giardia lamblia Hexose transporter 0.0031 0.0177 0.1213
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0274 0.0412
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0146 0.1384 0.2162
Toxoplasma gondii Alpha-galactosidase 0.0016 0.0022 0.0016
Brugia malayi hypothetical protein 0.0031 0.0177 0.0202
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0177 0.0167
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0113 0.0307
Echinococcus multilocularis lysyl tRNA synthetase 0.0049 0.0367 0.0366
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0042 0.0289 0.1458
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0068 0.0568 0.1665
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0021 0.0073 0.0189
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2152 0.2601
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0068 0.0568 0.0637
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0049 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0177 0.0167
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0059
Onchocerca volvulus 0.0031 0.0177 0.0167
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0567 0.0557
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0347 0.1005
Toxoplasma gondii facilitative glucose transporter GT1 0.022 0.2152 0.3372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Echinococcus multilocularis GPCR, family 2 0.0065 0.0538 0.0542
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.009 0.008
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0057 0.0047
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0021 0.0073 0.0189
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0031 0.0177 0.0778
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0012 0.0002
Chlamydia trachomatis lysine--tRNA ligase 0.0049 0.0367 0.1891
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0178 0.1713 0.268
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0621 0.0697
Echinococcus multilocularis cysteine protease 0.0019 0.0057 0.0046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0053 0.0127
Brugia malayi Sugar transporter family protein 0.0031 0.0177 0.0202
Schistosoma mansoni hypothetical protein 0.0141 0.1331 0.1603
Plasmodium falciparum thioredoxin reductase 0.0019 0.0053 0.0042
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0274 0.0786
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.0448 0.0449
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0057 0.0055
Echinococcus multilocularis solute carrier family 22 0.0031 0.0177 0.017
Loa Loa (eye worm) hypothetical protein 0.0091 0.0803 0.0905
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0078
Trypanosoma brucei protein kinase, putative 0.012 0.1109 0.3276
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0021 0.0073 0.0075
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0049 0.0045
Onchocerca volvulus 0.0031 0.0177 0.0167
Trypanosoma brucei glucose transporter, putative 0.0068 0.0567 0.1659
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.0428 0.1247
Onchocerca volvulus 0.0031 0.0177 0.0167
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0568 0.0676
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0057 0.0055
Toxoplasma gondii sugar transporter ST1 0.0031 0.0177 0.026
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0066 0.0543 0.1783
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0049 0.0056
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0049 0.0039
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0048 0.0055
Echinococcus multilocularis serine protein kinase ATM 0.0029 0.0156 0.0148
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0049 0.0038
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0178 0.1713 1
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0076 0.0648 0.0638
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.012 0.1109 0.3276
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Echinococcus multilocularis solute carrier family 22 0.0031 0.0177 0.017
Brugia malayi hypothetical protein 0.0019 0.0051 0.0059
Schistosoma mansoni zinc finger protein 0.0033 0.0194 0.0221
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0124 0.1148 0.3392
Brugia malayi Bromodomain containing protein 0.0081 0.0706 0.0805
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.1384 0.1375
Schistosoma mansoni caspase-3 (C14 family) 0.0298 0.2974 0.36
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.0658 0.193
Leishmania major metacaspase, putative 0.0146 0.1384 0.4097
Trypanosoma brucei glucose transporter, putative 0.0068 0.0567 0.1659
Toxoplasma gondii hypothetical protein 0.0061 0.0494 0.076
Loa Loa (eye worm) hypothetical protein 0.0019 0.0057 0.0054
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0568 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.1384 0.1375
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0021 0.0073 0.0189
Echinococcus granulosus solute carrier family 22 0.0031 0.0177 0.02
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0049 0.0045
Schistosoma mansoni glucose transport protein 0.022 0.2152 0.2601
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0537 0.5469 0.6233
Schistosoma mansoni zinc finger protein 0.0042 0.0289 0.0337
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0055 0.0052
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0124 0.1148 0.1309
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0274 0.4318
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0243 0.0695
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2152 0.2601
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0178 0.1713 1
Brugia malayi MH2 domain containing protein 0.0116 0.1062 0.1211
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0112 0.1023 0.1157
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0068 0.0562 0.1644
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0125 0.1164 0.6746
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0356 0.3579 0.562
Toxoplasma gondii sugar transporter ST3 0.0031 0.0177 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.0371 0.3737 0.373
Toxoplasma gondii exonuclease III APE 0.0019 0.0048 0.0057
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0053 0.0127
Brugia malayi Cam kinase protein 1 0.0068 0.0568 0.0648
Echinococcus granulosus muscleblind protein 0.0163 0.1556 0.1876
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0021 0.0073 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Plasmodium falciparum lysine--tRNA ligase 0.0049 0.0367 0.0369
Schistosoma mansoni protein kinase 0.0068 0.0568 0.0676
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0177 0.0773
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0159 0.1515 0.4487
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0053 0.0043
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0021 0.0073 0.0063
Brugia malayi RNA, U transporter 1 0.0079 0.0684 0.078
Leishmania major mitochondrial DNA polymerase beta 0.0336 0.3364 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0055 0.0044
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0048 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0049 0.0116
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0029 0.0156 0.0433
Leishmania major cathepsin L-like protease 0.0074 0.0629 0.1845
Trypanosoma cruzi metacaspase, putative 0.0146 0.1384 0.4097
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0298 0.0347
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0053 0.006
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0146 0.0404
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0049 0.0636
Loa Loa (eye worm) bromodomain containing protein 0.0038 0.0247 0.027
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0073 0.0072
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0049 0.0367 0.1063
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0336 0.3364 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0146 0.1384 0.2162
Echinococcus multilocularis peptidase Clp (S14 family) 0.0117 0.1072 0.1094
Brugia malayi Cathepsin L-like precursor 0.0019 0.0057 0.0065
Treponema pallidum NADH oxidase 0.0019 0.0053 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0352 0.3538 0.3532
Giardia lamblia NADH oxidase lateral transfer candidate 0.0019 0.0053 0.0043
Loa Loa (eye worm) fibroinase 0.0019 0.0057 0.0054
Echinococcus multilocularis geminin 0.0518 0.527 0.5423
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.016 0.0154
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0066 0.0543 0.062
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0658 0.193
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Trypanosoma brucei glucose transporter, putative 0.0068 0.0567 0.1659
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.022 0.2152 0.2207
Giardia lamblia Kinase, CMGC MAPK 0.012 0.1109 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0048 0.0355 0.0417
Onchocerca volvulus 0.0019 0.0057 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.0118
Loa Loa (eye worm) hypothetical protein 0.0141 0.1331 0.1508
Brugia malayi Melibiase family protein 0.0076 0.0648 0.0739
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0114 0.1044 0.1065
Leishmania major trypanothione reductase 0.0055 0.0428 0.1247
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0057 0.0769
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0068 0.0568 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Mycobacterium tuberculosis Conserved hypothetical protein 0.0177 0.1703 1
Onchocerca volvulus Glucosylceramidase homolog 0.0352 0.3538 0.3532
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Onchocerca volvulus 0.0019 0.0057 0.0047
Leishmania major protein kinase, putative 0.0068 0.0568 0.1665
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0621 0.1821
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Trypanosoma brucei glucose transporter, putative 0.0068 0.0567 0.1659
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.001 0.0012
Leishmania major hypothetical protein, conserved 0.0033 0.0194 0.0549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0352 0.3538 0.3532
Echinococcus granulosus serine protein kinase ATM 0.0029 0.0156 0.0174
Echinococcus granulosus microtubule associated protein 2 0.0802 0.8239 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0057 0.0054
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0567 0.1659
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0156 0.0145
Plasmodium falciparum calcium-dependent protein kinase 4 0.0068 0.0569 0.0579
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0274 0.0264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Loa Loa (eye worm) hypothetical protein 0.0028 0.0146 0.0155
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0097 0.0268
Trichomonas vaginalis sugar transport protein, putative 0.0031 0.0177 0.0167
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0114 0.1044 0.1254
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0068 0.0569 0.0579
Giardia lamblia Lysyl-tRNA synthetase 0.0049 0.0367 0.3003
Giardia lamblia Sugar-proton symporter 0.0031 0.0177 0.1213
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0178 0.1713 1
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0049 0.0367 0.1063
Brugia malayi hypothetical protein 0.0492 0.5002 0.5704
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.2969 0.3379
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0053 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Loa Loa (eye worm) hypothetical protein 0.0029 0.016 0.0171
Onchocerca volvulus 0.0019 0.0057 0.0047
Echinococcus multilocularis lysosomal alpha glucosidase 0.0181 0.1747 0.179
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Entamoeba histolytica hypothetical protein 0.0023 0.009 0.1312
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0177 0.017
Schistosoma mansoni hypothetical protein 0.0065 0.0538 0.0639
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0181 0.1747 0.1983
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Schistosoma mansoni hypothetical protein 0.0212 0.2066 0.2497
Trichomonas vaginalis myo-inositol transporter, putative 0.0031 0.0177 0.0167
Trypanosoma brucei glucose transporter, putative 0.0068 0.0567 0.1659
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.5469 0.5465
Schistosoma mansoni glucose transport protein 0.022 0.2152 0.2601
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0568 0.0574
Entamoeba histolytica hypothetical protein 0.0049 0.0367 0.5837
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0146 0.1384 0.1579
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0068 0.0568 0.0648
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0117 0.1072 0.55
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0489 0.497 0.5663
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0019 0.0053 0.0028
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0016 0.0022 0.0012
Onchocerca volvulus 0.0019 0.0057 0.0047
Loa Loa (eye worm) hypothetical protein 0.015 0.1428 0.1618
Toxoplasma gondii FATC domain-containing protein 0.0029 0.0156 0.0226
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0274 0.0264
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Loa Loa (eye worm) hypothetical protein 0.0068 0.0568 0.0637
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0298 0.2974 0.36
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0178 0.1713 0.177
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0274 0.0786
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0031 0.0177 0.0497
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.009 0.0239
Schistosoma mansoni importin beta-1 0.0028 0.0146 0.0162
Trichomonas vaginalis glucosylceramidase, putative 0.0352 0.3538 0.3532
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0942 0.9707 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0021 0.0073 0.0075
Echinococcus multilocularis microtubule associated protein 2 0.0802 0.8239 0.8486
Echinococcus granulosus fetal alzheimer antigen falz 0.0048 0.0355 0.0417
Trichomonas vaginalis glucosylceramidase, putative 0.0352 0.3538 0.3532
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0336 0.3364 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0053 0.0064
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0567 0.1659
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.1132 0.1362
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0053 0.0064
Plasmodium vivax proline--tRNA ligase, putative 0.0077 0.0658 0.0672
Brugia malayi Cell death protein 3 precursor 0.0358 0.3596 0.4102
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0021 0.0073 0.0075
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0125 0.1164 0.6746
Trypanosoma brucei unspecified product 0.0019 0.0049 0.0116
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0068 0.0569 0.0877
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0077 0.0658 0.1017
Trypanosoma cruzi target of rapamycin kinase 3 0.0021 0.0073 0.0189
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1062 0.1201
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0053 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0057 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.1384 0.1375
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0021 0.0073 0.0189
Trypanosoma cruzi ISWI complex protein 0.0033 0.0194 0.0549
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2152 0.2601
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trichomonas vaginalis CMGC family protein kinase 0.012 0.1109 0.11
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Loa Loa (eye worm) hypothetical protein 0.0049 0.0367 0.0407
Echinococcus granulosus thioredoxin glutathione reductase 0.0055 0.0428 0.0506
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2152 0.2207
Toxoplasma gondii cathepsin CPL 0.0019 0.0057 0.0071
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0375 0.0374
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.1085 0.1304
Schistosoma mansoni hypothetical protein 0.022 0.2152 0.2601
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0057 0.0047
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0125 0.1164 0.6746
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0274 0.0264
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0159 0.1512 0.1547
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0177 0.0773
Leishmania major phosphatidylinositol 3-kinase, putative 0.0021 0.0073 0.0189
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0298 0.0295
Loa Loa (eye worm) glutathione reductase 0.0055 0.0428 0.0477
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0177 0.0202
Leishmania major hypothetical protein, conserved 0.0029 0.016 0.0447
Schistosoma mansoni alpha glucosidase 0.004 0.0274 0.0318
Onchocerca volvulus 0.0031 0.0177 0.0167
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0177 0.0171
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0178 0.1713 0.1754
Brugia malayi hypothetical protein 0.0212 0.2066 0.2356
Brugia malayi Cathepsin L-like precursor 0.0019 0.0057 0.0065
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0455 0.1327
Plasmodium vivax importin-beta 2, putative 0.0028 0.0146 0.0139
Echinococcus granulosus lysyl tRNA synthetase 0.0049 0.0367 0.0431
Brugia malayi Sugar transporter family protein 0.022 0.2152 0.2454
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0114 0.1044 0.1254
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0057 0.0065
Leishmania major cathepsin L-like protease 0.0074 0.0629 0.1845
Echinococcus granulosus geminin 0.0518 0.527 0.6391
Echinococcus multilocularis solute carrier family 22 0.0031 0.0177 0.017
Brugia malayi Cathepsin L-like precursor 0.0019 0.0057 0.0065
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0125 0.1164 0.6147
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0207 0.2015 0.2289
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0069 0.0089
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0057 0.0055
Onchocerca volvulus 0.0492 0.5002 0.4997
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Echinococcus granulosus caspase 3 0.0152 0.1444 0.174
Brugia malayi jmjC domain containing protein 0.0015 0.0012 0.0014
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0621 0.074
Entamoeba histolytica hypothetical protein 0.0029 0.0156 0.238
Plasmodium falciparum glutathione reductase 0.0019 0.0053 0.0042
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0048 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0352 0.3538 0.3532
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0053 0.0127
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0298 0.2974 0.3055
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Schistosoma mansoni ran 0.0021 0.0069 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.016 0.0447
Leishmania major glucose transporter/membrane transporter D2, putative 0.0068 0.0567 0.1659
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0178 0.1713 0.177
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0124 0.1148 0.138
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0048 0.0038
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0053 0.0127
Brugia malayi jmjC domain containing protein 0.0015 0.0012 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0177 0.0167
Loa Loa (eye worm) hypothetical protein 0.0066 0.0543 0.0609
Entamoeba histolytica protein kinase, putative 0.0068 0.0568 0.9141
Brugia malayi lysyl-tRNA synthetase 0.0049 0.0367 0.0418
Schistosoma mansoni lozenge 0.0062 0.05 0.0592
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0621 0.0708
Loa Loa (eye worm) hypothetical protein 0.0178 0.1713 0.1944
Loa Loa (eye worm) hypothetical protein 0.0212 0.2066 0.2347
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0137 0.0144
Brugia malayi Bromodomain containing protein 0.016 0.1523 0.1737
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0375 0.0441
Echinococcus multilocularis thioredoxin glutathione reductase 0.0055 0.0428 0.0429
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0069 0.0068
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Plasmodium vivax glutathione reductase, putative 0.0055 0.0428 0.0433
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0124 0.1148 0.6605
Brugia malayi major facilitator superfamily protein 0.0031 0.0177 0.0202
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0274 0.0264
Echinococcus granulosus importin subunit beta 1 0.0028 0.0146 0.0162
Toxoplasma gondii melibiase subfamily protein 0.0114 0.1044 0.1626
Loa Loa (eye worm) ctsf protein 0.0019 0.0057 0.0054
Echinococcus granulosus dna polymerase eta 0.0019 0.0049 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.012 0.1109 0.11
Onchocerca volvulus 0.0122 0.1132 0.1123
Loa Loa (eye worm) hypothetical protein 0.0492 0.5002 0.5699
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0029 0.0156 0.0433
Leishmania major cathepsin L-like protease 0.0019 0.0057 0.014
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0053 0.0042
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.0289 0.1458
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0074 0.019
Echinococcus granulosus caspase 0.0298 0.2974 0.36
Echinococcus granulosus calcium dependent protein kinase 0.0063 0.0514 0.061
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0097 0.0295
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0066 0.0543 0.0548
Toxoplasma gondii protein kinase, putative 0.0622 0.6359 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0076 0.0653 0.0779
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.1132 0.1765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0146 0.021
Leishmania major DNA polymerase eta, putative 0.0019 0.0049 0.0116
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0053 0.0127
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0029 0.0156 0.0174
Echinococcus multilocularis zinc finger protein 0.0042 0.0289 0.0286
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0538 0.0613
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0048 0.0037
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0274 0.0264
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0178 0.1713 0.2067
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0012 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.049 0.0548
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0053 0.0127
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0069 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0567 0.0557
Brugia malayi Cathepsin L-like precursor 0.0019 0.0057 0.0065
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0012 0.0002
Plasmodium falciparum calcium-dependent protein kinase 3 0.0068 0.0569 0.0579
Trypanosoma brucei metacaspase 0.0146 0.1384 0.4097
Onchocerca volvulus 0.0031 0.0177 0.0167
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0124 0.1148 0.138
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0567 0.0557
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0367 0.0431
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.012 0.1109 0.3276
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0069 0.0174
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0852 0.8768 1
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0049 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Echinococcus multilocularis caspase 8 0.0146 0.1384 0.1415
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0568 0.0676
Trypanosoma brucei glucose transporter 1E 0.0068 0.0567 0.1659
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0049 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.022 0.2152 0.2144
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Schistosoma mansoni sugar transporter 0.0031 0.0177 0.02
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0207 0.2015 0.2298
Echinococcus multilocularis snurportin 1 0.0298 0.2969 0.305
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0114 0.1044 0.1254
Brugia malayi jmjC domain containing protein 0.0061 0.049 0.0559
Brugia malayi major facilitator superfamily protein 0.0031 0.0177 0.0202
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0538 0.0542
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0068 0.0569 0.0579
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0021 0.0073 0.0189
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0177 0.017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Echinococcus multilocularis caspase 2 0.0358 0.3596 0.3697
Echinococcus granulosus apoptotic protease activating factor 1 0.0212 0.2066 0.2497
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0567 0.1659
Trypanosoma cruzi metacaspase, putative 0.0146 0.1384 0.4097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0537 0.5469 0.5465
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0049 0.0039
Onchocerca volvulus 0.0031 0.0177 0.0167
Onchocerca volvulus 0.0031 0.0177 0.0167
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.012 0.1109 0.1255
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0347 0.1005
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0177 0.02
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0274 0.0301
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0057 0.0047
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0567 0.0557
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0053 0.0127
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0567 0.0557
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0048 0.0622
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0066 0.0543 0.0646
Echinococcus granulosus dna polymerase kappa 0.0019 0.0049 0.0045
Loa Loa (eye worm) hypothetical protein 0.0159 0.1512 0.1715
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0621 0.1821
Leishmania major hypothetical protein, conserved 0.0031 0.0177 0.0497
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0069 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0159 0.1512 0.1823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0274 0.4318
Onchocerca volvulus Cell death protein 3 homolog 0.0358 0.3596 0.359
Echinococcus multilocularis cysteine protease 0.0019 0.0057 0.0046
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Echinococcus multilocularis dna polymerase eta 0.0019 0.0049 0.0038
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.012 0.1109 0.3276
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0057 0.0046
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Giardia lamblia DINP protein human, muc B family 0.0019 0.0049 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0629 0.1845
Loa Loa (eye worm) hypothetical protein 0.0207 0.2015 0.2289
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0538 0.0613
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0177 0.02
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0069 0.0191
Giardia lamblia GTOR 0.0021 0.0073 0.0238
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0177 0.019
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Plasmodium falciparum thioredoxin reductase 0.0055 0.0428 0.0433
Loa Loa (eye worm) hypothetical protein 0.0163 0.1556 0.1765
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0048 0.0113
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0347 0.1005
Trypanosoma cruzi metacaspase, putative 0.0146 0.1384 0.4097
Onchocerca volvulus 0.0031 0.0177 0.0167
Schistosoma mansoni hypothetical protein 0.0065 0.0538 0.0639
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0012 0.0002
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0049 0.0116
Echinococcus granulosus mitogen activated protein kinase 3 0.012 0.1109 0.1333
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0053 0.0127
Plasmodium vivax hypothetical protein, conserved 0.0146 0.1384 0.1428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0537 0.5469 0.6238
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0053 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0629 0.1845
Loa Loa (eye worm) hypothetical protein 0.0492 0.5002 0.5699
Schistosoma mansoni glucose transport protein 0.022 0.2152 0.2601
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0057 0.0046
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0057 0.0046
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0146 0.0138
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0139 0.1311 0.763
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Trypanosoma brucei glucose transporter, putative 0.0068 0.0567 0.1659
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0146 0.1384 0.1375
Trypanosoma cruzi ISWI complex protein 0.0033 0.0194 0.0549
Schistosoma mansoni ap endonuclease 0.0019 0.0048 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0057 0.0047
Schistosoma mansoni hypothetical protein 0.0518 0.527 0.6391
Loa Loa (eye worm) hypothetical protein 0.0031 0.0177 0.019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0375 0.0441
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0021 0.0073 0.0189
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0114 0.1044 0.1065
Mycobacterium tuberculosis Probable reductase 0.0125 0.1164 0.6746
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0053 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Loa Loa (eye worm) hypothetical protein 0.0358 0.3596 0.4095
Loa Loa (eye worm) sugar transporter 0.0031 0.0177 0.019
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Plasmodium vivax lysine--tRNA ligase, putative 0.0049 0.0367 0.0369
Leishmania major cathepsin L-like protease 0.0019 0.0057 0.014
Echinococcus granulosus cathepsin l1 0.0019 0.0057 0.0055
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.009 0.008
Plasmodium falciparum protein kinase 6 0.0934 0.962 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0073 0.0063
Plasmodium falciparum calcium-dependent protein kinase 2 0.0068 0.0569 0.0579
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0097 0.0295
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0057 0.0054
Trypanosoma cruzi sugar transporter, putative 0.0031 0.0177 0.0497
Plasmodium vivax calcium-dependent protein kinase, putative 0.0068 0.0569 0.0579
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0021 0.0073 0.0075
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0019 0.0053 0.0028
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0177 0.0202
Onchocerca volvulus 0.0031 0.0177 0.0167
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0021 0.0073 0.0189
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.0233 0.0269
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0177 0.0167
Mycobacterium ulcerans sugar transporter 0.0031 0.0177 0.0773
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0049 0.0116
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.016 0.0154
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0274 0.0264
Trichomonas vaginalis ran, putative 0.0021 0.0069 0.0058
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0629 0.1845
Plasmodium falciparum metacaspase 1 0.0146 0.1384 0.1428

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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