Detailed information for compound 675946

Basic information

Technical information
  • TDR Targets ID: 675946
  • Name: (2,4-dimethylphenyl) 5-bromo-2-methoxybenzene sulfonate
  • MW: 371.246 | Formula: C15H15BrO4S
  • H donors: 0 H acceptors: 2 LogP: 4.41 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1S(=O)(=O)Oc1ccc(cc1C)C)Br
  • InChi: 1S/C15H15BrO4S/c1-10-4-6-13(11(2)8-10)20-21(17,18)15-9-12(16)5-7-14(15)19-3/h4-9H,1-3H3
  • InChiKey: KAKOONUDMATZFW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2,4-dimethylphenyl) 5-bromo-2-methoxy-benzenesulfonate
  • 5-bromo-2-methoxybenzenesulfonic acid (2,4-dimethylphenyl) ester
  • 5-bromo-2-methoxy-benzenesulfonic acid (2,4-dimethylphenyl) ester
  • ZINC02999810

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0143 0.0569 0.0899
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0031 0.0046
Onchocerca volvulus 0.0143 0.0569 0.0899
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Schistosoma mansoni neuropeptide F-like receptor 0.0143 0.0569 0.0903
Brugia malayi Carboxylesterase family protein 0.0019 0.0032 0.0028
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0257 0.1061 0.0986
Brugia malayi prolyl oligopeptidase family protein 0.0031 0.0083 0.0078
Echinococcus multilocularis Glutaredoxin protein 5 0.0058 0.0198 0.0312
Loa Loa (eye worm) neuropeptide F receptor 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0014 0.0007 0.0008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0038 0.0111 0.1922
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0131 0.0517 0.082
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.0035 0.0031
Onchocerca volvulus 0.0076 0.0278 0.0435
Brugia malayi G-protein coupled receptor 0.0143 0.0569 0.0565
Schistosoma mansoni neuropeptide F-like receptor 0.0143 0.0569 0.0903
Onchocerca volvulus 0.0019 0.0032 0.0044
Loa Loa (eye worm) AGC/NDR protein kinase 0.003 0.008 0.0075
Schistosoma mansoni neurotransmitter gated ion channel 0.0023 0.005 0.0076
Brugia malayi G protein-coupled receptor 0.0143 0.0569 0.0565
Echinococcus multilocularis neuropeptide FF receptor 2 0.0143 0.0569 0.0903
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0143 0.0569 0.0565
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0278 0.0439
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0044 0.0137 0.0215
Brugia malayi hypothetical protein 0.025 0.103 0.1025
Echinococcus granulosus neuropeptides capa receptor 0.0143 0.0569 0.0903
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0035 0.0031
Entamoeba histolytica prolyl oligopeptidase family protein 0.0031 0.0083 0.0608
Trypanosoma brucei C-8 sterol isomerase, putative 0.2322 1 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0076 0.0278 0.0273
Schistosoma mansoni kinesin eg-5 0.002 0.0035 0.0052
Onchocerca volvulus 0.0143 0.0569 0.0899
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0143 0.0569 0.0903
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.1285 1
Onchocerca volvulus 0.0348 0.1456 0.2312
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0022 0.0044 0.0186
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0019 0.0032 0.0048
Echinococcus granulosus neuropeptide Y receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis nAChR subunit 0.0023 0.005 0.0076
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0023 0.0018
Loa Loa (eye worm) neuropeptide F receptor 0.0143 0.0569 0.0565
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0054 0.0231
Echinococcus granulosus serotonin transporter 0.0348 0.1456 0.2315
Loa Loa (eye worm) hypothetical protein 0.0594 0.2519 0.2515
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0143 0.0569 0.0565
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0022 0.0044 0.0186
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.004 0.0122 0.0118
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0557 0.2361 1
Toxoplasma gondii aspartyl protease 0.0076 0.0278 0.486
Echinococcus granulosus 7tm_1 domain containing protein 0.0143 0.0569 0.0903
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0044 0.0137 0.0132
Onchocerca volvulus 0.0038 0.0111 0.017
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.0035 0.0053
Plasmodium vivax aspartyl protease, putative 0.0076 0.0278 0.4829
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus tm gpcr rhodopsin 0.0143 0.0569 0.0903
Brugia malayi prolyl oligopeptidase family protein 0.0257 0.1061 0.1056
Echinococcus multilocularis rac serine:threonine kinase 0.0064 0.0227 0.0359
Plasmodium falciparum plasmepsin IV 0.0144 0.057 1
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0029 0.0074 0.0111
Echinococcus granulosus g protein coupled receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Echinococcus granulosus hypothetical protein 0.0728 0.3098 0.493
Trichomonas vaginalis AGC family protein kinase 0.003 0.008 0.0589
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0028
Schistosoma mansoni cathepsin D (A01 family) 0.0316 0.1315 0.2091
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0044 0.0137 0.0132
Onchocerca volvulus 0.0143 0.0569 0.0899
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0019 0.0032 0.0048
Echinococcus multilocularis serine:threonine protein kinase N2 0.003 0.008 0.0124
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0111 0.0174
Echinococcus granulosus BC026374 protein S09 family 0.0019 0.0032 0.0048
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0183 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0012 0.0002 0.0009
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0137 0.0132
Echinococcus multilocularis para nitrobenzyl esterase 0.0019 0.0032 0.0048
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.001 0.0038
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0044 0.0137 0.0215
Schistosoma mansoni nAChR subunit 0.0044 0.0137 0.0215
Echinococcus multilocularis carboxylesterase 5A 0.0114 0.0444 0.0704
Onchocerca volvulus 0.002 0.0035 0.0049
Mycobacterium tuberculosis Probable reductase 0.0022 0.0044 0.0186
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.0035 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.003 0.008 0.0124
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus glycine receptor subunit alpha 1 0.0044 0.0137 0.0215
Echinococcus multilocularis orexin receptor type 2 0.0143 0.0569 0.0903
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0278 0.4825
Echinococcus granulosus sodium and chloride dependent glycine 0.0161 0.0645 0.1023
Loa Loa (eye worm) hypothetical protein 0.0076 0.0278 0.0273
Trichomonas vaginalis set domain proteins, putative 0.0299 0.1241 0.9657
Brugia malayi Carboxylesterase family protein 0.0019 0.0032 0.0028
Echinococcus granulosus dro:myosuppressin receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.0158 0.0631 0.0626
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0019 0.0032 0.0215
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0278 0.0439
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0059 0.0202 0.3485
Loa Loa (eye worm) kinesin-like protein KLP2 0.002 0.0035 0.003
Brugia malayi Dopamine receptor protein 1 0.0143 0.0569 0.0565
Echinococcus granulosus g protein coupled receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) TYRA-2 protein 0.0143 0.0569 0.0565
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0014 0.001 0.0012
Brugia malayi Probable DNA topoisomerase II 0.004 0.0122 0.0118
Schistosoma mansoni DNA topoisomerase II 0.004 0.0122 0.0191
Schistosoma mansoni vesicular acetylcholine transporter 0.1463 0.6282 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0044 0.0137 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.1285 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0348 0.1456 0.1452
Schistosoma mansoni voltage-gated potassium channel 0.0063 0.0219 0.0346
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.0601 0.2546
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Trypanosoma brucei rac serine-threonine kinase, putative 0.0094 0.0355 0.0274
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0076 0.0278 0.044
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0044 0.0137 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0083 0.0608
Mycobacterium ulcerans aldehyde dehydrogenase 0.0012 0.0002 0.0009
Giardia lamblia Deoxynucleoside kinase 0.0222 0.0907 0.7052
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0355 0.2735
Echinococcus granulosus nervana 2 0.0058 0.0198 0.0312
Trypanosoma brucei DNA topoisomerase ii 0.0032 0.0085 0.0003
Echinococcus multilocularis protein kinase c epsilon type 0.003 0.008 0.0124
Echinococcus granulosus neuropeptide receptor A26 0.0143 0.0569 0.0903
Giardia lamblia Alanyl dipeptidyl peptidase 0.0031 0.0083 0.0608
Plasmodium falciparum kinesin-5 0.002 0.0035 0.0512
Onchocerca volvulus 0.0143 0.0569 0.0899
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.001 0.0038
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0032
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0023 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0111 0.0174
Schistosoma mansoni neuropeptide receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis serotonin receptor 0.0976 0.4174 0.6642
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0143 0.0569 0.0565
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0058 0.0198 0.0311
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.002 0.0035 0.0053
Echinococcus granulosus neuropeptides capa receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.016 0.0639 0.0635
Brugia malayi Kinesin motor domain containing protein 0.002 0.0035 0.003
Schistosoma mansoni amine GPCR 0.0143 0.0569 0.0903
Echinococcus multilocularis acetylcholinesterase 0.0114 0.0444 0.0704
Brugia malayi putative neuropeptide receptor NPR1 0.0143 0.0569 0.0565
Echinococcus multilocularis conserved hypothetical protein 0.0584 0.2478 0.3942
Entamoeba histolytica DNA topoisomerase II, putative 0.004 0.0122 0.0918
Brugia malayi Carboxylesterase family protein 0.0019 0.0032 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0031 0.0083 0.0128
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0031 0.0083 0.008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.1285 1
Echinococcus multilocularis protein kinase c iota type 0.003 0.008 0.0124
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Brugia malayi hypothetical protein 0.002 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Onchocerca volvulus Putative nachr subunit 0.0044 0.0137 0.0211
Loa Loa (eye worm) norepinephrine transporter 0.0348 0.1456 0.1452
Brugia malayi Protein kinase domain containing protein 0.003 0.008 0.0075
Loa Loa (eye worm) hypothetical protein 0.0114 0.0444 0.044
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Schistosoma mansoni sodium/chloride dependent transporter 0.0348 0.1456 0.2315
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0137 0.0132
Plasmodium vivax aspartyl protease, putative 0.0076 0.0278 0.4829
Brugia malayi hypothetical protein 0.002 0.0035 0.0031
Loa Loa (eye worm) carboxylesterase 0.0114 0.0444 0.044
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0019 0.0032 0.0048
Brugia malayi Protein kinase domain containing protein 0.003 0.008 0.0075
Loa Loa (eye worm) aspartyl protease 6 0.0076 0.0278 0.0274
Brugia malayi hypothetical protein 0.01 0.0383 0.0379
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0013 0.0005 0.0045
Echinococcus granulosus allatostatin A receptor 0.0143 0.0569 0.0903
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0143 0.0569 0.0903
Mycobacterium ulcerans aldehyde dehydrogenase 0.0012 0.0002 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Schistosoma mansoni serine/threonine protein kinase 0.003 0.008 0.0124
Echinococcus multilocularis neuroligin 0.0019 0.0032 0.0048
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0076 0.0278 0.0273
Plasmodium vivax amine transporter, putative 0.0076 0.0278 0.4825
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0014 0.0007 0.0008
Echinococcus multilocularis serine threonine protein kinase 0.003 0.008 0.0124
Brugia malayi Eukaryotic aspartyl protease family protein 0.0076 0.0278 0.0274
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0044 0.0137 0.0215
Onchocerca volvulus 0.0143 0.0569 0.0899
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0257 0.1061 0.1056
Echinococcus granulosus protein kinase c iota type 0.003 0.008 0.0124
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0044 0.0137 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni sodium-dependent amino acid transporter 0.0076 0.0278 0.0439
Plasmodium vivax plasmepsin IV, putative 0.0144 0.057 1
Brugia malayi hypothetical protein 0.0076 0.0278 0.0273
Schistosoma mansoni amine GPCR 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Brugia malayi Protein kinase domain containing protein 0.0094 0.0355 0.035
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0045
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0014 0.0007 0.0008
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.057 0.0904
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0143 0.0569 0.0903
Brugia malayi Muscleblind-like protein 0.0314 0.1307 0.1303
Echinococcus multilocularis GPCR, family 2 0.0017 0.0023 0.0032
Giardia lamblia DNA topoisomerase II 0.0038 0.0115 0.0858
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Loa Loa (eye worm) carboxylesterase 0.0019 0.0032 0.0028
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0023 0.0018
Onchocerca volvulus 0.016 0.0639 0.1011
Loa Loa (eye worm) hypothetical protein 0.0144 0.057 0.0566
Schistosoma mansoni serine/threonine protein kinase 0.003 0.008 0.0124
Schistosoma mansoni growth hormone secretagogue receptor 0.0143 0.0569 0.0903
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.001 0.0012
Brugia malayi GnHR receptor homolog 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0044 0.0137 0.0215
Giardia lamblia Kinase, AGC PKA 0.0059 0.0202 0.1544
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0044 0.0137 0.0215
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0044 0.0137 0.0215
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0278 0.0439
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.003 0.008 0.0124
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0045
Onchocerca volvulus 0.0076 0.0278 0.0436
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0035 0.0053
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0143 0.0569 0.0903
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.063 0.2674 0.4254
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0044 0.0137 0.0132
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0023 0.005 0.0045
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0161 0.0645 0.064
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0257 0.1061 0.1056
Schistosoma mansoni voltage-gated potassium channel 0.0063 0.0219 0.0346
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Echinococcus granulosus neuropeptide receptor 0.0143 0.0569 0.0903
Giardia lamblia Fructose-bisphosphate aldolase 0.0309 0.1285 1
Brugia malayi Cation transporter family protein 0.016 0.0639 0.0635
Schistosoma mansoni alpha-1 adrenergic receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Loa Loa (eye worm) melatonin receptor type 1A 0.0143 0.0569 0.0565
Toxoplasma gondii prolyl endopeptidase 0.0031 0.0083 0.1416
Schistosoma mansoni acetylcholine receptor subunit beta 0.002 0.0035 0.0053
Loa Loa (eye worm) hypothetical protein 0.003 0.008 0.0075
Loa Loa (eye worm) hypothetical protein 0.0037 0.0109 0.0104
Schistosoma mansoni neuropeptide receptor 0.0143 0.0569 0.0903
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0013 0.0006 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.0976 0.4174 0.6642
Echinococcus granulosus neuropeptide receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0023 0.0032
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0044 0.0137 0.0215
Onchocerca volvulus 0.002 0.0035 0.0049
Leishmania major C-8 sterol isomerase-like protein 0.2322 1 1
Entamoeba histolytica hypothetical protein 0.0023 0.005 0.0354
Plasmodium vivax plasmepsin V, putative 0.0076 0.0278 0.4829
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0242 0.0995 0.158
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0031 0.0083 0.0128
Brugia malayi prolyl oligopeptidase family protein 0.0031 0.0083 0.0078
Chlamydia trachomatis DNA gyrase subunit B 0.0022 0.0043 0.1363
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0058 0.0198 0.0312
Echinococcus multilocularis serotonin transporter 0.0348 0.1456 0.2315
Brugia malayi hypothetical protein 0.0019 0.0032 0.0028
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0076 0.0278 0.0439
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Onchocerca volvulus 0.0143 0.0569 0.0899
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0083 0.1362
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0137 0.0132
Echinococcus granulosus Protein kinase C brain isozyme 0.003 0.008 0.0124
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0169 0.0164
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0144 0.057 0.4418
Loa Loa (eye worm) hypothetical protein 0.0076 0.0278 0.0273
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0348 0.1456 0.1452
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0083 0.0078
Onchocerca volvulus 0.0143 0.0569 0.0899
Trypanosoma cruzi DNA topoisomerase II, putative 0.0036 0.0105 0.01
Plasmodium vivax SET domain protein, putative 0.0038 0.0111 0.1872
Brugia malayi hypothetical protein 0.0076 0.0278 0.0274
Brugia malayi G protein-coupled receptor F59B2.13 0.0143 0.0569 0.0565
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0058 0.0198 0.0193
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0019 0.0032 0.0048
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0076 0.0278 0.044
Brugia malayi ORL1-like opioid receptor 0.0143 0.0569 0.0565
Echinococcus multilocularis BC026374 protein (S09 family) 0.0019 0.0032 0.0048
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0137 0.0132
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Brugia malayi hypothetical protein 0.002 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0183 0.0178
Brugia malayi aspartic protease BmAsp-1, identical 0.0076 0.0278 0.0274
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0355 0.2735
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0076 0.0278 0.0439
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0014 0.0007 0.0008
Brugia malayi AKH receptor 0.0143 0.0569 0.0565
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0152 0.0147
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.0601 0.2405
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Entamoeba histolytica protein kinase, putative 0.0094 0.0355 0.2735
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0044 0.0137 0.0215
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0045
Loa Loa (eye worm) hypothetical protein 0.0158 0.0631 0.0626
Schistosoma mansoni neuropeptide receptor 0.0143 0.0569 0.0903
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0031 0.0083 0.0078
Echinococcus granulosus neuropeptide Y receptor 0.0143 0.0569 0.0903
Plasmodium falciparum plasmepsin V 0.0076 0.0278 0.4829
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0044 0.0137 0.0132
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0023 0.005 0.0045
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0031 0.0046
Echinococcus granulosus acetylcholinesterase 0.0114 0.0444 0.0704
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0143 0.0569 0.0903
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.0601 0.2546
Echinococcus multilocularis fmrfamide receptor 0.0143 0.0569 0.0903
Echinococcus granulosus protein kinase c epsilon type 0.003 0.008 0.0124
Echinococcus granulosus muscleblind protein 0.0314 0.1307 0.2077
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.001 0.0012
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0029 0.0074 0.0111
Schistosoma mansoni opsin-like receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis glycine receptor subunit beta 0.0044 0.0137 0.0215
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni hypothetical protein 0.0143 0.0569 0.0903
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.002 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus GPCR family 2 0.0017 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Schistosoma mansoni serine/threonine kinase 0.003 0.008 0.0124
Onchocerca volvulus 0.0143 0.0569 0.0899
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.002 0.0035 0.0053
Brugia malayi Carboxylesterase family protein 0.0019 0.0032 0.0028
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0131 0.0517 0.082
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0031 0.0083 0.0608
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0076 0.0278 0.0439
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0076 0.0278 0.044
Echinococcus multilocularis glycine receptor subunit beta 0.0044 0.0137 0.0215
Brugia malayi Serotonin receptor 0.0143 0.0569 0.0565
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0076 0.0278 0.0439
Loa Loa (eye worm) hypothetical protein 0.0031 0.0083 0.0078
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0143 0.0569 0.0903
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0023 0.005 0.0076
Brugia malayi Carboxylesterase family protein 0.0114 0.0444 0.044
Schistosoma mansoni adenoreceptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) AGC/AKT protein kinase 0.0094 0.0355 0.035
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0257 0.1061 0.0986
Echinococcus multilocularis G protein coupled receptor 139 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0076 0.0278 0.0273
Onchocerca volvulus 0.0023 0.005 0.0072
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0076 0.0278 0.0439
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.003 0.008 0.0124
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.005 0.0045
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0183 0.0178
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0144 0.057 0.0904
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0044 0.0137 0.0215
Onchocerca volvulus Prolyl endopeptidase homolog 0.0031 0.0083 0.0124
Echinococcus multilocularis somatostatin receptor 0.0143 0.0569 0.0903
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0143 0.0569 0.0903
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0242 0.0995 0.158
Brugia malayi RE15519p 0.0143 0.0569 0.0565
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0044 0.0137 0.0132
Onchocerca volvulus 0.0044 0.0137 0.0211
Schistosoma mansoni histamine h1 receptor 0.0143 0.0569 0.0903
Entamoeba histolytica protein kinase, putative 0.0088 0.033 0.254
Trichomonas vaginalis AGC family protein kinase 0.0036 0.0105 0.0784
Echinococcus granulosus nAChR subunit 0.0023 0.005 0.0076
Plasmodium vivax aspartyl proteinase, putative 0.0076 0.0278 0.4829
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0076 0.0278 0.0273
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0058 0.0198 0.0312
Mycobacterium ulcerans carboxylesterase, LipT 0.0019 0.0032 0.0137
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0023 0.0018
Toxoplasma gondii kinesin motor domain-containing protein 0.002 0.0035 0.057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0111 0.0107
Echinococcus multilocularis neuropeptides capa receptor 0.0143 0.0569 0.0903
Trichomonas vaginalis DNA topoisomerase II, putative 0.004 0.0122 0.0918
Brugia malayi prolyl oligopeptidase family protein 0.0031 0.0083 0.0078
Loa Loa (eye worm) G-protein coupled receptor 0.0143 0.0569 0.0565
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0029 0.0074 0.0111
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0028
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0054 0.0182 0.1388
Schistosoma mansoni opsin-like receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0024 0.0054 0.0231
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0044 0.0137 0.0215
Echinococcus granulosus NDR protein kinase 0.003 0.008 0.0124
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.003 0.008 0.0075
Entamoeba histolytica kinesin, putative 0.002 0.0035 0.0233
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0019 0.0032 0.0137
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0076 0.0278 0.044
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Echinococcus granulosus somatostatin receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0036 0.0105 0.0022
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0137 0.0132
Echinococcus granulosus tachykinin peptides receptor 99D 0.0397 0.1667 0.2652
Loa Loa (eye worm) G-protein coupled receptor 0.0143 0.0569 0.0565
Brugia malayi hypothetical protein 0.002 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0976 0.4174 0.4171
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.002 0.0035 0.0031
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0076 0.0278 0.044
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Plasmodium falciparum plasmepsin VI 0.0144 0.057 1
Echinococcus multilocularis fmrfamide receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis nAChR subunit 0.0044 0.0137 0.0215
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0031 0.0083 0.1416
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0021
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0257 0.1061 0.1685
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0038 0.0111 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Entamoeba histolytica prolyl oligopeptidase family protein 0.0031 0.0083 0.0608
Loa Loa (eye worm) AGC/PKN protein kinase 0.003 0.008 0.0075
Plasmodium falciparum plasmepsin III 0.0076 0.0278 0.4829
Loa Loa (eye worm) hypothetical protein 0.016 0.0639 0.0635
Echinococcus granulosus vesicular acetylcholine transporter 0.1463 0.6282 1
Brugia malayi Melatonin receptor type 1A 0.0143 0.0569 0.0565
Trypanosoma cruzi Protein kinase B 0.0064 0.0227 0.0223
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.001 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0143 0.0569 0.0903
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0044 0.0137 0.0215
Loa Loa (eye worm) hypothetical protein 0.0348 0.1456 0.1452
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Echinococcus multilocularis sex peptide receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Brugia malayi p70 ribosomal S6 kinase beta 0.0088 0.033 0.0325
Trichomonas vaginalis spcc417.12 protein, putative 0.0019 0.0032 0.0215
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Brugia malayi excitatory GABA receptor EXP-1A 0.0044 0.0137 0.0132
Onchocerca volvulus 0.0076 0.0278 0.0435
Echinococcus multilocularis dro:myosuppressin receptor 0.0143 0.0569 0.0903
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.0035 0.0053
Loa Loa (eye worm) hypothetical protein 0.0139 0.0552 0.0548
Schistosoma mansoni sodium/chloride dependent transporter 0.0161 0.0645 0.1023
Loa Loa (eye worm) serotonin transporter b 0.0348 0.1456 0.1452
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0058 0.0198 0.0193
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0137 0.0132
Brugia malayi sulfakinin receptor protein 0.0594 0.2519 0.2515
Echinococcus multilocularis neuropeptide Y receptor 0.0143 0.0569 0.0903
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0137 0.0132
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0021
Schistosoma mansoni hypothetical protein 0.0143 0.0569 0.0903
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0143 0.0569 0.0903
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.1285 1
Onchocerca volvulus 0.0023 0.005 0.0072
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0018
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.0557 0.2361 1
Echinococcus multilocularis serine:threonine protein kinase 38 0.003 0.008 0.0124
Entamoeba histolytica prolyl oligopeptidase family protein 0.0031 0.0083 0.0608
Echinococcus granulosus glycine receptor subunit alpha 1 0.0044 0.0137 0.0215
Echinococcus granulosus glycine receptor subunit beta 0.0044 0.0137 0.0215
Echinococcus granulosus histone lysine methyltransferase setb 0.0038 0.0111 0.0174
Echinococcus granulosus neuropeptide FF receptor 2 0.0143 0.0569 0.0903
Loa Loa (eye worm) ACC-1 protein 0.0044 0.0137 0.0132
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0014 0.0007 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0083 0.0078
Echinococcus multilocularis allatostatin A receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0044 0.0137 0.0215
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni hypothetical protein 0.0037 0.0109 0.0169
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.001 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0028
Echinococcus multilocularis neuropeptide receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis neuropeptides capa receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0314 0.1307 0.1303
Giardia lamblia Kinesin-5 0.002 0.0035 0.0233
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0143 0.0569 0.0903
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0031 0.0083 0.0608
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0022 0.0044 0.0186
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.1285 1
Toxoplasma gondii hypothetical protein 0.0031 0.0083 0.1416
Onchocerca volvulus 0.0143 0.0569 0.0899
Echinococcus granulosus nervana 2 0.0058 0.0198 0.0312
Brugia malayi Pre-SET motif family protein 0.0262 0.1084 0.108
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Echinococcus multilocularis g-protein coupled receptor 0.0143 0.0569 0.0903
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0137 0.0132
Echinococcus multilocularis neuropeptide s receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0161 0.0645 0.064
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0038 0.0111 0.0174
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0076 0.0278 0.0439
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0059 0.0202 0.3485
Echinococcus granulosus orexin receptor type 2 0.0143 0.0569 0.0903
Plasmodium falciparum plasmepsin X 0.0076 0.0278 0.4829
Loa Loa (eye worm) hypothetical protein 0.2322 1 1
Brugia malayi Carboxylesterase family protein 0.0114 0.0444 0.044
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0278 0.4857
Loa Loa (eye worm) prolyl oligopeptidase 0.0031 0.0083 0.0078
Brugia malayi G-protein coupled receptor 0.0143 0.0569 0.0565
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0023 0.005 0.0076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0014 0.0007 0.0008
Schistosoma mansoni biogenic amine receptor 0.0143 0.0569 0.0903
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0143 0.0569 0.0903
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0144 0.057 1
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0143 0.0569 0.0565
Trichomonas vaginalis AGC family protein kinase 0.003 0.008 0.0589
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.001 0.0012
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0044 0.0137 0.0215
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0131 0.0517 0.082
Loa Loa (eye worm) hypothetical protein 0.0076 0.0278 0.0274
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0076 0.0278 0.044
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0031 0.0046
Trypanosoma cruzi DNA topoisomerase II, putative 0.0036 0.0105 0.01
Onchocerca volvulus 0.002 0.0035 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Echinococcus granulosus neuropeptide s receptor 0.0143 0.0569 0.0903
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0044 0.0137 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0028
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0022 0.0044 0.0186
Plasmodium falciparum plasmepsin IX 0.0076 0.0278 0.4829
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0031 0.0083 0.0078
Brugia malayi DNA topoisomerase II, alpha isozyme 0.004 0.0122 0.0118
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0076 0.0278 0.0439
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0032 0.0085 0.008
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0032
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis neuropeptide receptor A26 0.0143 0.0569 0.0903
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0143 0.0569 0.0903
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0076 0.0278 0.0439
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.016 0.0639 0.1014
Schistosoma mansoni nAChR subunit 0.002 0.0035 0.0053
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0044 0.0137 0.0132
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0076 0.0278 0.0439
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0355 0.2735
Loa Loa (eye worm) hypothetical protein 0.0054 0.0183 0.0178
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0076 0.0278 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0044 0.0137 0.0215
Schistosoma mansoni amine GPCR 0.0284 0.1176 0.1869
Onchocerca volvulus 0.0051 0.0169 0.0262
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.003 0.008 0.0124
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus glycine receptor subunit alpha 1 0.0044 0.0137 0.0215
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0014 0.001 0.0012
Onchocerca volvulus 0.0299 0.1241 0.1969
Loa Loa (eye worm) hypothetical protein 0.0157 0.0626 0.0622
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0044 0.0137 0.0215
Echinococcus granulosus peptide allatostatin:somatostatin 0.0143 0.0569 0.0903
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0013 0.0005 0.0004
Echinococcus granulosus hyperpolarization activated cyclic 0.0014 0.001 0.0012
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.001 0.0012
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0143 0.0569 0.0903
Brugia malayi neuropeptide F receptor 0.0143 0.0569 0.0565
Echinococcus granulosus acetylcholinesterase 0.0114 0.0444 0.0704
Echinococcus granulosus alpha 1A adrenergic receptor 0.0143 0.0569 0.0903
Schistosoma mansoni sodium/chloride dependent transporter 0.0162 0.0649 0.103
Plasmodium vivax DNA topoisomerase II, putative 0.004 0.0122 0.2065
Plasmodium vivax aspartyl proteinase, putative 0.0144 0.057 1
Echinococcus granulosus sex peptide receptor 0.0143 0.0569 0.0903
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0044 0.0137 0.0215
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0044 0.0137 0.0132
Entamoeba histolytica hypothetical protein, conserved 0.0031 0.0083 0.0608
Echinococcus multilocularis g protein coupled receptor 0.0143 0.0569 0.0903
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.1285 1
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0143 0.0569 0.0903
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0076 0.0278 0.486
Echinococcus multilocularis kinesin family 1 0.0153 0.0611 0.0969
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.006
Mycobacterium tuberculosis Probable dehydrogenase 0.0022 0.0044 0.0186
Onchocerca volvulus 0.0143 0.0569 0.0899
Plasmodium falciparum DNA topoisomerase 2 0.004 0.0122 0.2065
Brugia malayi NNMT/PNMT/TEMT family protein 0.0158 0.0631 0.0626
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.003 0.008 0.0124
Toxoplasma gondii aspartyl protease ASP3 0.0076 0.0278 0.486
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 0.1285 1
Echinococcus granulosus carboxylesterase 5A 0.0114 0.0444 0.0704
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0494 0.2086 0.2083
Echinococcus granulosus sodium and chloride dependent glycine 0.0161 0.0645 0.1023
Echinococcus granulosus kinesin family 1 0.0153 0.0611 0.0969
Schistosoma mansoni acetylcholine receptor-related 0.002 0.0035 0.0053
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0059 0.0202 0.0198
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Onchocerca volvulus 0.0044 0.0137 0.0211
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0348 0.1456 0.2315
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.002 0.0035 0.0053
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Onchocerca volvulus 0.016 0.0639 0.1011
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.003 0.008 0.0124
Echinococcus multilocularis survival motor neuron protein 1 0.025 0.103 0.1636
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.003 0.008 0.0124
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0036 0.0105 0.0164
Leishmania major mitochondrial DNA topoisomerase II 0.0032 0.0085 0.0083
Onchocerca volvulus 0.0019 0.0032 0.0044
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0044 0.0137 0.0215
Brugia malayi Tachykinin-like peptides receptor 99D 0.0143 0.0569 0.0565
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0013 0.0006 0.0061
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0083 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.003 0.008 0.0124
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0044 0.0137 0.0215
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0045
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0278 0.4857
Brugia malayi protein kinase C II. 0.003 0.008 0.0075
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0045
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0031 0.0083 0.0167
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0023 0.005 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.003 0.008 0.0124
Schistosoma mansoni survival motor neuron protein 0.0051 0.0169 0.0266
Mycobacterium leprae Probable cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.0557 0.2361 1
Schistosoma mansoni neuropeptide receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0143 0.0569 0.0903
Schistosoma mansoni opsin-like receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0059 0.0202 0.0319
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0355 0.2735
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.006
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0397 0.1667 0.2652
Plasmodium falciparum plasmepsin I 0.0144 0.057 1
Schistosoma mansoni cathepsin D (A01 family) 0.0316 0.1315 0.2091
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114 0.0444 0.0704
Loa Loa (eye worm) LGC-31 protein 0.0044 0.0137 0.0132
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0045
Echinococcus granulosus biogenic amine 5HT receptor 0.0143 0.0569 0.0903
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0024 0.0054 0.0231
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0143 0.0569 0.0903
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0131 0.0517 0.9068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0076 0.0278 0.044
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0278 0.0439
Echinococcus granulosus Dipeptidyl peptidase 9 0.0257 0.1061 0.1685
Loa Loa (eye worm) hypothetical protein 0.0976 0.4174 0.4171
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Echinococcus multilocularis serine:threonine protein kinase N2 0.003 0.008 0.0124
Loa Loa (eye worm) hypothetical protein 0.01 0.0383 0.0379
Loa Loa (eye worm) solute carrier family 6 member 4 0.0348 0.1456 0.1452
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0144 0.057 0.0566
Schistosoma mansoni nAChR subunit 0.002 0.0035 0.0053
Entamoeba histolytica PH domain containing protein kinase, putative 0.0064 0.0227 0.174
Echinococcus granulosus serotonin receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0242 0.0995 0.158
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0014 0.0007 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0038 0.0111 0.0174
Onchocerca volvulus 0.0076 0.0278 0.0435
Schistosoma mansoni serine/threonine-protein kinase 0.0064 0.0227 0.0359
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0076 0.0278 0.0439
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Echinococcus granulosus 7TM GPCR rhodopsin 0.0143 0.0569 0.0903
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0143 0.0569 0.0565
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.1285 1
Onchocerca volvulus 0.0143 0.0569 0.0899
Echinococcus granulosus tm gpcr rhodopsin 0.0143 0.0569 0.0903
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0031 0.0046
Giardia lamblia Alanyl dipeptidyl peptidase 0.0031 0.0083 0.0608
Brugia malayi larval opioid receptor 0.0143 0.0569 0.0565
Echinococcus granulosus Glutaredoxin protein 5 0.0058 0.0198 0.0312
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni nAChR subunit 0.0044 0.0137 0.0215
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0031 0.0083 0.0128
Mycobacterium ulcerans DNA gyrase subunit B 0.0013 0.0006 0.0024
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.003 0.008 0.0124
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0161 0.0645 0.064
Echinococcus granulosus fmrfamide receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.003 0.008 0.0075
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.0035 0.0031
Schistosoma mansoni memapsin-2 (A01 family) 0.0737 0.3138 0.4994
Echinococcus granulosus biogenic amine 5HT receptor 0.0976 0.4174 0.6642
Plasmodium falciparum plasmepsin VIII, putative 0.0076 0.0278 0.4829
Schistosoma mansoni myosin xvIII 0.0143 0.0569 0.0903
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.001 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Echinococcus multilocularis sodium and chloride dependent glycine 0.0161 0.0645 0.1023
Echinococcus multilocularis muscleblind protein 1 0.0314 0.1307 0.2077
Echinococcus multilocularis neuropeptide receptor 0.0143 0.0569 0.0903
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Brugia malayi Cyclic-nucleotide gated cation channel 0.0014 0.001 0.0005
Loa Loa (eye worm) acetylcholinesterase 1 0.0114 0.0444 0.044
Loa Loa (eye worm) ACC-1 protein 0.0044 0.0137 0.0132
Onchocerca volvulus 0.0143 0.0569 0.0899
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.1285 1
Echinococcus granulosus g-protein coupled receptor 0.0143 0.0569 0.0903
Brugia malayi aspartic protease BmAsp-2, identical 0.0076 0.0278 0.0274
Plasmodium falciparum amino acid transporter, putative 0.0076 0.0278 0.4825
Echinococcus granulosus survival motor neuron protein 1 0.025 0.103 0.1636
Echinococcus granulosus glycine receptor subunit beta 0.0044 0.0137 0.0215
Onchocerca volvulus 0.0019 0.0032 0.0044
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0031 0.0083 0.008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.039 0.1636 0.2602
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.003 0.008 0.0075
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0109 0.0104
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0143 0.0569 0.0903
Brugia malayi hypothetical protein 0.0076 0.0278 0.0274
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.003 0.008 0.0075
Brugia malayi follicle stimulating hormone receptor 0.0143 0.0569 0.0565
Echinococcus multilocularis rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0058 0.0198 0.0311
Brugia malayi Cation transporter family protein 0.0044 0.0137 0.0132
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0014 0.001 0.0012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0023 0.0032
Trypanosoma cruzi prolyl endopeptidase 0.0031 0.0083 0.0078
Schistosoma mansoni amine GPCR 0.0143 0.0569 0.0903
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0262 0.1084 0.108
Echinococcus multilocularis G-protein coupled receptor, putative 0.0143 0.0569 0.0903
Trypanosoma cruzi oligopeptidase b 0.0031 0.0083 0.0078
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0044 0.0137 0.0215
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0035 0.0053
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.1463 0.6282 1
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0014 0.001 0.0012
Plasmodium vivax aspartyl protease, putative 0.0076 0.0278 0.4829
Schistosoma mansoni acetylcholinesterase 0.0019 0.0032 0.0048
Echinococcus granulosus nAChR subunit 0.0044 0.0137 0.0215
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0013 0.0006 0.0024
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0036 0.0105 0.0022
Toxoplasma gondii hypothetical protein 0.0076 0.0278 0.4857
Entamoeba histolytica protein kinase, putative 0.003 0.008 0.0589
Leishmania major oligopeptidase b 0.0031 0.0083 0.008
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.016 0.0639 0.1014
Echinococcus granulosus serine/threonine protein kinase 0.0064 0.0227 0.0359
Echinococcus multilocularis serotonin receptor 0.0976 0.4174 0.6642
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0019 0.0032 0.0048
Schistosoma mansoni hypothetical protein 0.0143 0.0569 0.0903
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0013 0.0005 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0038 0.0111 0.0174
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0032 0.0085 0.008
Echinococcus multilocularis prolyl endopeptidase 0.0031 0.0083 0.0128
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0031 0.0083 0.0608
Schistosoma mansoni neuropeptide f receptor 76f 0.0143 0.0569 0.0903
Treponema pallidum fructose-bisphosphate aldolase 0.0309 0.1285 0.8817
Loa Loa (eye worm) hypothetical protein 0.0114 0.0444 0.044
Echinococcus granulosus tm gpcr rhodopsin 0.039 0.1636 0.2602
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni nAChR subunit 0.0044 0.0137 0.0215
Echinococcus granulosus DNA topoisomerase 2 alpha 0.004 0.0122 0.0191
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0044 0.0137 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 0.1285 1
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0088 0.033 0.0325
Schistosoma mansoni nAChR subunit 0.0044 0.0137 0.0215
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Loa Loa (eye worm) TOPoisomerase family member 0.004 0.0122 0.0118
Mycobacterium tuberculosis Probable peptidase 0.0031 0.0083 0.035
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni nAChR subunit 0.0044 0.0137 0.0215
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.002 0.0035 0.0031
Echinococcus granulosus protein kinase C gamma type 0.003 0.008 0.0124
Loa Loa (eye worm) hypothetical protein 0.0158 0.0631 0.0626
Brugia malayi Hr1 repeat family protein 0.003 0.008 0.0075
Onchocerca volvulus 0.0143 0.0569 0.0899
Echinococcus multilocularis sodium and chloride dependent glycine 0.0161 0.0645 0.1023
Plasmodium falciparum transporter, putative 0.0076 0.0278 0.4825
Onchocerca volvulus Neuropeptide F receptor homolog 0.0143 0.0569 0.0899
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0029 0.0076 0.0556
Plasmodium falciparum plasmepsin II 0.0144 0.057 1
Brugia malayi Pepsin A precursor 0.0076 0.0278 0.0274
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0143 0.0569 0.0903
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0031 0.0083 0.035
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0114 0.0444 0.0704
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0028
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0013 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus neuroligin 0.0019 0.0032 0.0048
Loa Loa (eye worm) hypothetical protein 0.0161 0.0645 0.064
Loa Loa (eye worm) hypothetical protein 0.0076 0.0278 0.0273
Echinococcus granulosus prolyl endopeptidase 0.0031 0.0083 0.0128
Echinococcus multilocularis acetylcholinesterase 0.0114 0.0444 0.0704
Echinococcus multilocularis hyperpolarization activated cyclic 0.0014 0.001 0.0012
Toxoplasma gondii AGC kinase 0.0088 0.033 0.5768
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0026
Plasmodium vivax kinesin-5 0.002 0.0035 0.0512
Schistosoma mansoni biogenic amine receptor 0.0143 0.0569 0.0903
Onchocerca volvulus 0.0019 0.0032 0.0044
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0076 0.0278 0.044
Loa Loa (eye worm) hypothetical protein 0.0314 0.1307 0.1303
Plasmodium falciparum plasmepsin VII 0.0076 0.0278 0.4829
Entamoeba histolytica protein kinase 2, putative 0.0059 0.0202 0.1544
Brugia malayi Cation transporter family protein 0.0044 0.0137 0.0132
Brugia malayi Serotonin receptor 0.0533 0.2255 0.2251
Schistosoma mansoni serine/threonine-protein kinase 0.0064 0.0227 0.0359
Echinococcus multilocularis acylamino acid releasing enzyme 0.0031 0.0083 0.0128
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0143 0.0569 0.0903
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0143 0.0569 0.0565
Toxoplasma gondii aspartyl protease ASP1 0.0144 0.057 1
Echinococcus multilocularis nervana 2 0.0058 0.0198 0.0312
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.1463 0.6282 0.628
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0012 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Brugia malayi prolyl oligopeptidase family protein 0.0131 0.0517 0.0513
Echinococcus granulosus para nitrobenzyl esterase 0.0019 0.0032 0.0048
Loa Loa (eye worm) acetylcholine receptor protein 0.002 0.0035 0.0031
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.001 0.0012
Treponema pallidum sodium- and chloride- dependent transporter 0.0348 0.1456 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0076 0.0278 0.0274
Schistosoma mansoni atypical protein kinase C 0.003 0.008 0.0124
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0064 0.0227 0.0223
Schistosoma mansoni BC026374 protein (S09 family) 0.0019 0.0032 0.0048
Loa Loa (eye worm) hypothetical protein 0.025 0.103 0.1025
Onchocerca volvulus 0.0019 0.0032 0.0044
Mycobacterium tuberculosis Carboxylesterase LipT 0.0019 0.0032 0.0137
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0076 0.0278 0.0274
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Brugia malayi Pre-SET motif family protein 0.0038 0.0111 0.0107
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0076 0.0278 0.0439
Trypanosoma cruzi oligopeptidase b 0.0031 0.0083 0.0078
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0044 0.0137 0.0132
Leishmania major DNA topoisomerase ii 0.0036 0.0105 0.0103
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni amine GPCR 0.0143 0.0569 0.0903
Echinococcus granulosus acylamino acid releasing enzyme 0.0031 0.0083 0.0128
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0355 0.2735
Schistosoma mansoni nAChR subunit 0.0044 0.0137 0.0215
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2322 1 1
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0257 0.1061 0.1685
Echinococcus multilocularis Protein kinase C, brain isozyme 0.003 0.008 0.0124
Schistosoma mansoni hypothetical protein 0.0051 0.0169 0.0266
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0031 0.0083 0.035
Echinococcus multilocularis g protein coupled receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0019 0.0032 0.0028
Echinococcus multilocularis neuropeptide Y receptor 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0076 0.0278 0.0273
Echinococcus granulosus G protein coupled receptor 139 0.0143 0.0569 0.0903
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0032
Schistosoma mansoni nAChR subunit 0.0044 0.0137 0.0215
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0024 0.0054 0.0046
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0044 0.0137 0.0215
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0143 0.0569 0.0899
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0131 0.0517 0.0816
Brugia malayi neuropeptide F receptor 0.0143 0.0569 0.0565
Echinococcus granulosus g protein coupled receptor 0.0143 0.0569 0.0903
Schistosoma mansoni neuroligin 3 (S09 family) 0.0019 0.0032 0.0048
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0144 0.057 0.0904
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0023 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0031 0.0083 0.0608
Loa Loa (eye worm) carboxylesterase 0.0019 0.0032 0.0028
Schistosoma mansoni gliotactin 0.0019 0.0032 0.0048
Toxoplasma gondii DNA topoisomerase 2, putative 0.004 0.0122 0.2114
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0019 0.0032 0.0137
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0044 0.0137 0.0132
Brugia malayi Dopamine receptor 0.0143 0.0569 0.0565
Schistosoma mansoni hypothetical protein 0.0133 0.0525 0.0832
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0143 0.0569 0.0565
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0143 0.0569 0.0903
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0076 0.0278 0.4857
Loa Loa (eye worm) GABA receptor subunit 0.0023 0.005 0.0045
Trichomonas vaginalis AGC family protein kinase 0.003 0.008 0.0589
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0143 0.0569 0.0565
Onchocerca volvulus 0.0044 0.0137 0.0211
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0045
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0032
Plasmodium falciparum peptidase, putative 0.0031 0.0083 0.1362
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Schistosoma mansoni biogenic amine (5HT) receptor 0.0143 0.0569 0.0903
Onchocerca volvulus 0.0143 0.0569 0.0899
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0257 0.1061 0.1059
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0044 0.0137 0.0215
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0143 0.0569 0.0903
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Brugia malayi putative neuropeptide receptor 0.0143 0.0569 0.0565
Schistosoma mansoni biogenic amine receptor 0.0143 0.0569 0.0903
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0143 0.0569 0.0903
Onchocerca volvulus 0.016 0.0639 0.1011
Toxoplasma gondii hypothetical protein 0.0076 0.0278 0.4857
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0031 0.0083 0.0128
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0076 0.0278 0.0273
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.004 0.0122 0.0191
Brugia malayi hypothetical protein 0.0594 0.2519 0.2515
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0031
Entamoeba histolytica PH domain containing protein kinase, putative 0.0064 0.0227 0.174
Loa Loa (eye worm) prolyl oligopeptidase 0.0131 0.0517 0.0513
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0143 0.0569 0.0903
Brugia malayi hypothetical protein 0.002 0.0035 0.0031
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0014 0.001 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.003 0.008 0.0124
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0014 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.005 0.0045
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0059 0.0202 0.0319
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0132
Onchocerca volvulus 0.0143 0.0569 0.0899
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0143 0.0569 0.0565
Schistosoma mansoni hypothetical protein 0.0143 0.0569 0.0903
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0054 0.0182 0.1388
Echinococcus multilocularis vesicular acetylcholine transporter 0.1463 0.6282 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0143 0.0569 0.0903
Onchocerca volvulus 0.0076 0.0278 0.0436
Entamoeba histolytica protein kinase, putative 0.0094 0.0355 0.2735
Brugia malayi vesicular acetylcholine transporter unc-17 0.1463 0.6282 0.628
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0143 0.0569 0.0903
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Loa Loa (eye worm) hypothetical protein 0.0494 0.2086 0.2083
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0031 0.0026
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0355 0.2735
Trichomonas vaginalis AGC family protein kinase 0.0094 0.0355 0.2735
Echinococcus granulosus serine:threonine protein kinase N2 0.003 0.008 0.0124
Echinococcus multilocularis nervana 2 0.0058 0.0198 0.0312
Onchocerca volvulus 0.0143 0.0569 0.0899
Loa Loa (eye worm) hypothetical protein 0.0143 0.0569 0.0565
Echinococcus granulosus serine threonine protein kinase nrc 0.0059 0.0202 0.0319
Loa Loa (eye worm) hypothetical protein 0.1187 0.5086 0.5084
Brugia malayi hypothetical protein 0.0143 0.0569 0.0565
Echinococcus multilocularis muscleblind protein 0.0314 0.1307 0.2077
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0137 0.0132
Brugia malayi Dopamine receptor protein 2 0.0143 0.0569 0.0565
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0348 0.1456 0.1452

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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